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1 No improvement occurred when frequencies mismatched.
2 CB) units and patients are often HLA class I mismatched.
3 tion, which is MHC-matched but minor antigen-mismatched.
4 3% [n = 142]; 8/10, 38.2% [n = 60]; MICA-129 mismatched 10/10, 3.9% [n = 54]; 9/10, 10.2% [n = 65]; 8
5 ased with the number of HLA mismatches (MICA mismatched 10/10, 9.2% [n = 127]; 9/10, 22.3% [n = 142];
6 ved in the 10/10 match group if MICA-129 was mismatched (10/10, hazard ratio [HR], 1.77; confidence i
7 le mismatched, 70% (65-75) after two alleles mismatched, 62% (57-68) after three alleles mismatched,
8 er HLA matched, 76% (71-81) after one allele mismatched, 70% (65-75) after two alleles mismatched, 62
9 is compact structure by an electrostatically mismatched A86K mutation profoundly affected the DNA bin
10 resent a new statistical algorithm, MACHETE (Mismatched Alignment CHimEra Tracking Engine), which ach
13 rsus-solid tumor (GvT) effects following MHC-mismatched allogeneic bone marrow transplantation (allo-
14 MDSCs significantly prolonged the fully MHC mismatched allogeneic cardiac graft survival in a donor-
15 reliably evade immune rejection in fully MHC-mismatched allogeneic recipients and survive long-term w
16 se interactions induces tolerance in a fully mismatched allogeneic splenocyte transfer model in mice.
17 ing an immunocompetent murine model of minor mismatched allogeneic transplantation followed by donor-
19 m and immunosuppression withdrawal in highly mismatched allograft recipients using a bioengineered st
21 ed multiple minor histocompatibility antigen-mismatched alloHCT using bone marrow (BM) cells and sple
23 rovided by specificity analysis using single mismatched and complementary oligonucleotide sequences.
24 Using major histocompatibility complex (MHC)-mismatched and MHC-matched murine BMT models, we found t
27 ecipients, including 125 cord blood, 125 HLA-mismatched, and 154 HLA-matched HCTs, detection of multi
28 mismatched, 62% (57-68) after three alleles mismatched, and 49% (41-57) after four or more alleles m
30 to Mycobacterium tuberculosis in MHC class I-mismatched animals, as well as from Th1-biased dams to T
31 his phase 1 and 2 trial, we administered HLA-mismatched anti-CD19 CAR-NK cells derived from cord bloo
33 In both a minor histocompatibility antigen-mismatched as well as a MHC-haploidentical model of scle
34 unrelated donor (fully matched or one-locus mismatched at HLA-A, HLA-B, HLA-C, or DRB1 loci) graft f
35 nce of transfused semiallogeneic donor cells mismatched at major histocompatibility class I can enhan
36 tween transplantations that were matched and mismatched at one allele (HR 1.18, 95% CI 0.80-1.72, p=0
37 , mortality was higher with transplantations mismatched at two (hazard ratio [HR] 1.55, 95% CI 1.08-2
38 accelerated in KO recipients of MHC class II-mismatched B6.C-H-2(bm12) heart transplants versus wild-
39 ney transplantation model that subjected MHC-mismatched BALB/c kidney allografts to cold-ischemia sto
40 howed that CC (PEG MG) islets from fully MHC-mismatched Balb/c mice supported long-term (>100 days) s
43 e of efficiency for incorporation of various mismatched base pairs and have uncovered a mechanism in
44 mainly include DNAzymes, G-quadruplexes, and mismatched base pairs and nanomaterials cover gold nanop
49 iniscent of DNA repair enzymes that displace mismatched bases, and is differentiated from other DNA-t
53 enotoxic conditioning protocol for fully MHC-mismatched bone marrow allotransplantation in mice invol
55 hibitory and excitatory inputs are initially mismatched but become co-tuned or balanced with experien
56 ed major histocompatibility complex class II mismatched C57BL/6N (H-2; B6) or B6.RIP3 (H-2; RIP3) mic
59 Tregs led to long-term survival of fully MHC-mismatched cardiac allografts, and prevented development
61 ) but not wild-type mice receiving fully MHC-mismatched cardiac transplants became tolerant and showe
62 ceded by a briefly presented matched-case or mismatched-case identity prime (e.g., ALTAR-ALTAR vs. al
65 In contrast, we observe that binocularly mismatched cells are more mismatched in orientation tuni
67 uses, the utility of vaccines in the face of mismatched circulating strains remains questionable.
69 ClpP rings, it remains unknown how symmetry mismatched ClpX and ClpP work in tandem for processive s
70 vity of neurons only from the same region in mismatched cocultures, exhibiting region-matched astrocy
71 ts complexes with perfect-matched and single-mismatched complementary DNA molecules were examined by
72 th of epitaxial nanocomposites using lattice-mismatched constituents also enables strain-engineering,
73 rget miRNA-21 from its single- and four-base-mismatched counterparts and another non-complementary mi
74 Simulations using 46 ICPs and 11 fully HLA-mismatched CPs were undertaken using the Australian KPD
75 of an RPBA cutoff with RPBA data) and assay-mismatched cutoffs (e.g., with the use of microbiologic
77 ciency for assay-matched compared with assay-mismatched cutoffs were 5.6% compared with 16% (serum fo
78 s that use ecologically- and physiologically-mismatched diets over-estimate susceptibility and under-
79 4) tetrahedron binds to single stranded DNA, mismatched DNA base pairs, and three-way DNA junctions.
81 a high selectivity that discriminates single-mismatched DNA from fully matched target DNA under optim
84 EcMutL formed cascading sliding clamps on a mismatched DNA that together assisted EcMutH in introduc
85 after the first MVA-CMDR boost, the sequence-mismatched DNA-prime MVA-boost vaccine strategy induced
86 ear of transplant (P = 0.015), having an HLA-mismatched donor (P < 0.001), and being a male recipient
87 alysis, GF was associated with having an HLA-mismatched donor (P < 0.05) or MUD (P = 0.015) and with
88 s of acute leukemia, a transplant from a HLA-mismatched donor and from cord blood, older age, and dur
89 med bone marrow transplantations between age-mismatched donor and recipient mice to test the influenc
90 n associated with de novo antibodies against mismatched donor HLA antigens in kidney transplantation.
92 r-specific antibodies (DSA) directed against mismatched donor human leukocyte antigen (HLA) is a majo
94 ound that human and minor histocompatibility-mismatched donor mouse heart allografts with alloimmune-
101 ues with two sequential skin grafts from MHC-mismatched donors; four of them were also desensitized w
105 This work showcases how to resolve symmetry-mismatched elements in a large eukaryotic virus and prov
107 131 is responsible for the great majority of mismatched empirical antibiotic prescriptions for suspec
110 reen for antibodies against genotype-derived mismatched epitopes in 25 patients with biopsy-confirmed
113 lly, these gamma rhythms were linked back to mismatched expectations or "luck" occurring in past tria
117 bserved in a patient, HLA 10/10 matched, but mismatched for HLA-DRB3 and HLA-DPB1 compared with the d
118 thin each HLA match group, cases matched and mismatched for MICA and MICA-129 were analyzed for the e
119 ol schemes considered for neural systems are mismatched for the unique needs of manipulating neural d
121 (MVA)-boost vaccination strategy, which uses mismatched Gag immunogens in the TamoVac 01 phase IIa tr
122 donors were increasingly older, female sex, mismatched gender (female donor with a male recipient),
126 ion where early rejection of immunologically mismatched grafts is driven by the recipient's natural k
128 with primary immunodeficiencies received 155 mismatched grafts: 30 T-cell receptor (TCR) alphabeta/CD
129 d ratios were lower (hazard ratio in the HLA-mismatched group, 1.36; 95% CI, 0.76 to 2.46; P=0.30; ha
130 he cord-blood group (hazard ratio in the HLA-mismatched group, 3.01; 95% CI, 1.22 to 7.38; P=0.02; ha
133 biology of human leukocyte antigen haplotype mismatched ("haploidentical") transplantation, its trans
134 multiple viruses included cord blood or HLA-mismatched HCT, myeloablative conditioning, and acute gr
136 transplantation of a minor antigen (HY) sex-mismatched heart graft, the lymphatic flow index was sig
137 oablative conditioning for HLA class I or II mismatched hematopoietic cell transplantation (HCT).
139 a new defect elimination strategy in highly mismatched heteroepitaxy is demonstrated to achieve a ul
141 s recognized primary leukemic cells when the mismatched HLA class II allele was shared between NE-CBU
145 clonal CD4 T cell response against patient's mismatched HLA-DRB3 molecule was found in addition to an
148 approaches for transplanting immunologically mismatched HSCs and solid organs with limited toxicity.
149 he decreased melting temperature of the tL.C mismatched hybrid as compared to that of the t.C mismatc
150 atched hybrid as compared to that of the t.C mismatched hybrid, while the melting temperatures of the
155 d excitatory neural responses were initially mismatched in the cortex of naive mice, with untuned inh
157 s were influenza A(H1N1) and vaccine lineage-mismatched influenza B/Victoria; the VE for fully vaccin
158 17-2018, influenza A(H3N2), H1N1 and lineage-mismatched influenza B/Yamagata cocirculated; VE was sta
160 ch as lithium polysulfide shuttling effects, mismatched interfaces, Li dendrite growth, and the gap b
164 Here we addressed these questions using HLA-mismatched liver allografts to discriminate the liver-re
165 en achieved in recipients of HLA-matched and mismatched living donor kidney transplants in 3 medical
168 owever, when two Y-STR haplotypes have a few mismatched loci, it is difficult to determine if they ar
169 ciated with higher irritability, only in the mismatched, low-high and high-low maternal anxiety group
177 ngent major histocompatibility complex fully mismatched mouse models were used to evaluate the alloim
178 full major histocompatibility complex (MHC)-mismatched, multiorgan system model with BO, donor T-cel
179 indefinite allograft survival in a fully MHC mismatched murine cardiac transplant model in the absenc
180 ted significantly improved discrimination of mismatched (mutant) alleles from matched (wild-type) all
181 The direct growth of Pt islands on lattice mismatched Ni nanoparticles is a major synthetic challen
182 owing double selection, recipient cells with mismatched nuclear (nDNA) and mitochondrial (mtDNA) geno
184 the capacity of CoVs to proofread and remove mismatched nucleotides during genome replication and tra
185 utative off-target sites, which have 3 and 1 mismatched nucleotides with GhMYB25-like-sgRNA1 and GhMY
187 ng the proportions of reacting peptides with mismatched numbers of complementary reactive groups resu
190 ligation of pol beta insertion products with mismatched or damaged nucleotides, with the exception of
192 nger than the geranylated T-A pair and other mismatched pairs in the B-form DNA duplex context, which
195 nor-derived target cells transduced with the mismatched patient variant HLA-DRB3 and HLA-DPB1 molecul
197 that depend on resources showing temporally mismatched patterns should be expected to schedule routi
199 gainst 2 meningococcal outbreak strains with mismatched PorA and heterologous FHbp subfamily B sequen
203 copy synthetic and natural templates, extend mismatched primer termini, and bypass secondary DNA stru
205 ion with isothermal DNA amplification, using mismatched primers in conjunction with a two-round enric
209 rain (44/76-SL, which included fHbp) and one mismatched reference strain (5/99, which included neisse
210 ion from matched unrelated donors (MUDs) and mismatched related donors (MMRDs) in patients with prima
212 with myeloid malignancy and those receiving mismatched related/haploidentical grafts, were 80% (+/-6
215 zation strategy, we sensitized maximally MHC-mismatched rhesus pairs with two sequential skin transpl
217 tients with suspected CTEPH, the presence of mismatched segmental defects being consistent with the d
220 ing difficulties in heteroepitaxy of lattice-mismatched semiconductors of desired functionalities but
222 ete discrimination against single nucleotide mismatched sequences under practical conditions and high
223 etection limits (<7 pM) "perfect-match" from mismatched sequences, down to a single nucleotide mutati
230 mice prior to transplantation of a fully MHC mismatched skin allograft resulted in prolonged allograf
231 mice also delayed rejection of major antigen-mismatched skin and MHC class II-mismatched cardiac allo
232 ansplant of minor histocompatibility Ag (HY)-mismatched skin grafts from TORC2(DC-/-) donors into wil
236 resonance (MR) imaging of donor-matched and mismatched stem cell transplants demonstrated decreased
240 predetermined angles of the ligands and the mismatched structural tensions created from the multi-la
241 th syngenic MHC-matched and in allogenic MHC-mismatched studies as C57BL/6 (H-2(b)) and BALB/cBy (H-2
242 hrough an interface of refractive index (RI)-mismatched substances (i.e., a discrepancy between the R
247 he monolithic integration of largely lattice-mismatched systems by covering a wide range of the misfi
248 time, conventional heteroepitaxy of lattice-mismatched systems produces dislocations above a critica
250 NA distinguishing perfect-matched and single-mismatched target DNA molecules to the best extent, like
252 ound that xCas9 has the lowest tolerance for mismatched target sequences and that SpCas9-NG has the b
253 ing for both perfectly matched and partially mismatched target sequences in a Saccharomyces cerevisia
255 MgdNTP-prebinding ability could stabilize a mismatched ternary complex and destabilize a matched ter
256 ion performance, when it matched rather than mismatched the concurrently memorized content, despite i
257 dent on whether the TMS frequency matched or mismatched the expected underlying task-driven oscillati
258 ystem in which MHC-matched but minor antigen-mismatched tissue (skin) grafts were transplanted into M
260 forests to become increasingly structurally mismatched to water availability and thus overbuilt duri
264 3%) HLA-matched and 1457 (4.3%) single HLA-B-mismatched transplantations using multivariate regressio
268 ndicated proper discrimination capability to mismatched two-base, three-base, and non-complementary s
269 HCT using matched unrelated (n = 25, 55.5%), mismatched unrelated (n = 14, 31.1%), or mismatched rela
270 (n = 1), HLA-matched unrelated (n = 9), HLA-mismatched unrelated (n = 3), and HLA haploidentical sib
272 y and long-term outcome in matched (MUD) and mismatched unrelated donor (mMUD) setting is not well de
274 ny age with a haploidentical relative or HLA-mismatched unrelated donor and patients age 13 years or
275 han 25 x 10(9)/L before transplantation, HLA-mismatched unrelated donor, ASXL1 mutation, and non-CALR
276 related donors (1.43, 0.81-2.50; p=0.21) or mismatched unrelated donors (1.17, 0.67-2.05; p=0.58) ve
277 ated donors (3.71, 2.39-5.75; p<0.0001), and mismatched unrelated donors (4.34, 2.58-7.32; p<0.0001)
278 cell donors were matched unrelated donors or mismatched unrelated donors (n = 18) and matched related
279 nors were matched unrelated donors (n = 72), mismatched unrelated donors (n = 37), matched sibling do
280 .58) versus HLA-matched unrelated donors, or mismatched unrelated donors versus haploidentical relate
284 e HLA-B leader informs GVHD risk after HLA-B-mismatched unrelated HCT and differentiates high-risk HL
286 D-related outcomes were higher in HLA-DP GVH-mismatched unrelated recipients than in HLA-matched sibl
288 ied were matched sibling, matched unrelated, mismatched unrelated, haploidentical, and cord blood don
289 r types (matched sibling, matched unrelated, mismatched unrelated, haploidentical, and umbilical cord
290 ted: 49.1% [48.0-50.2] to 51.6% [50.7-52.6]; mismatched unrelated: 37.4% [35.7-39.2] to 41.3% [39.5-4
292 rall graft failure risk was higher among HLA-mismatched versus HLA-matched transplants (adjusted haza
293 ates a unique and unusually dynamic symmetry-mismatched vertex that is central to building an infecti
294 the parental T3D strain, we found that this mismatched virus was less stable and completed conformat
296 rs to fully major histocompatibility complex-mismatched Wistar Furth rat or C57 mouse recipients with
297 phic levels may result in predators becoming mismatched with prey availability, reducing fitness and
298 hanced neural representations of speech that mismatched with prior expectations, but led to greater s
299 form of the query - a text-based string - is mismatched with the form of the target - a genomic profi