ライフサイエンスコーパス: misuse

1 ption drug misuse, and over-the-counter drug misuse).

2 rge codes included opioid and/or amphetamine misuse.

3 avoidance strategy which can lead to alcohol misuse.

4 avoidance strategy that can lead to alcohol misuse.

5 re often excessive in size, which encourages misuse.

6 leave unused opioids available for potential misuse.

7 as the most commonly reported motivation for misuse.

8 s may be associated with prescription opioid misuse.

9 r relatives for their most recent episode of misuse.

10 d the first GEWIS examining risk for alcohol misuse.

11 ures, which would help preventing antibiotic misuse.

12 heir importance across dimensions of alcohol misuse.

13 s that target opioid storage, packaging, and misuse.

14 icularly if they are comorbid with substance misuse.

15 ve approach to help screen for possible drug misuse.

16 e of this subthalamic network across alcohol misuse.

17 chronic pain promotes higher rates of opioid misuse.

18 erventions) may improve treatment of alcohol misuse.

19 t score positively on the M-SASQ for alcohol misuse.

20 and oral cancer that can result from alcohol misuse.

21 order, criminality, accidents, and substance misuse.

22 consistently associated with greater alcohol misuse.

23 us diseases, mental disorders, and substance misuse.

24 itiation of substance use and progression to misuse.

25 are effective in the reduction of substance misuse.

26 ng substantial risk of misinterpretation and misuse.

27 l counseling interventions to reduce alcohol misuse.

28 number of misconceptions and their frequent misuse.

29 sistant infections and preventing antibiotic misuse.

30 y its potential for accidental or deliberate misuse.

31 ave an elevated risk of subsequent substance misuse.

32 s of neighborhood social distress and opioid misuse.

33 therapy and to potentially reduce antibiotic misuse.

34 determined for respondents reporting opioid misuse.

35 Citation metrics are widely used and misused.

36 etworks, the MM rate law has frequently been misused.

37 88-4.56]; p<0.001) and no history of alcohol misuse (0.47 [0.24-0.92]; p=0.027).

38 ession or anxiety (0.91, 0.71-1.16), alcohol misuse (0.88, 0.73-1.06), or seeking support for mental

39 ogical distress 1.34, 0.98-1.85), or alcohol misuse (1.32, 0.97-1.80).

40 atient with mental illness, alcohol and drug misuse (19 victims [66%], 27 perpetrators [93%]) and pre

41 Among adults with misuse, 59.9% reported using opioids without a prescript

42 duce the risk of adverse outcomes, including misuse, abuse, addiction, and overdose, arising from use

43 adverse effects of opioids and the risks of misuse, abuse, and overdose in the nonpatient population

44 ntin (GBP), a prescription drug, is prone to misuse, abuse, withdrawal, and dependence.

45 medication compliance, drug substitution, or misuse/abuse and require follow-up confirmatory testing

46 Previous work has shown patients commonly misuse adrenaline autoinjectors (AAI).

47 na and recreational drugs, prescription drug misuse (adult gender expression only), and consumption o

48 Minimal data exists regarding opioid misuse after endocrine surgical operations.

49 rventions most effective at reducing alcohol misuse after traumatic injury is not known.

50 in those without, particularly in people who misuse alcohol and hard drugs.

51 of IPV and (b) their male partner's alcohol misuse among couples in urban Zambia.

52 ndary care to detect alcohol consumption and misuse among people diagnosed with psoriasis.

53 d call for a proactive step away from colour misuse among the community, publishers, and the press.

54 isuse, and use disorders and motivations for misuse among U.S. adults.

55 sics for clinical pain management, but their misuse and abuse have led to the current opioid epidemic

56 Australia, experiencing epidemics of opioid misuse and abuse over this period.

57 pioids and hence risk of prescription opioid misuse and abuse remains a healthcare concern and a chal

58 Among PLHIV on COT, opioid misuse and awareness of the addictive potential of COT a

59 rmed diagnosis is a key driver of antibiotic misuse and could inform antimicrobial stewardship interv

60 Opioid misuse and deaths are increasing in the United States.

61 tment, and prevention of prescription opioid misuse and dependence.

62 nges in gene expression that lead to alcohol misuse and dependence.

63 accompanying Special Issue on Substance Use, Misuse and Dependence.

64 he further benefit of obviating the risk for misuse and diversion of daily buprenorphine while retain

65 collects and analyzes postmarketing data on misuse and diversion of prescription opioid analgesics a

66 Unused opioids are also subject to misuse and diversion, and they may cause addiction.

67 ation in susceptibility to opioid medication misuse and eventual addiction in the context of chronic

68 Recent trends in methamphetamine (METH) misuse and overdose suggest society is inadvertently ove

69 susceptibility testing (AST) would decrease misuse and overuse of antibiotics.

70 Further interventions to reduce misuse and overuse of antimicrobials in high-consumption

71 antidoping fight is the elimination of drug misuse and prevention of severe adverse effects caused b

72 , there is evidence of widespread continuing misuse and promulgation of poor-quality and insufficient

73 en adults aged 18 years or older for alcohol misuse and provide persons engaged in risky or hazardous

74 ine the feasibility of screening for alcohol misuse and providing brief intervention in a primary den

75 potential contributor to patterns of opioid misuse and related harm.

76 odels shed light on the aetiology of alcohol misuse and suggest targets for prevention.

77 to estimate associations between opioid use/misuse and suicidal behaviors and propensity score-weigh

78 search has shown associations between opioid misuse and suicidal behaviors, but the relationship betw

79 y measure of alcohol consumption and alcohol misuse and to explore the shared genetic basis between t

80 wide Association Study (GWAS) of alcohol use/misuse and two family history (mother DSM-5 AUD and fath

81 Misuse and use disorders were most commonly reported in

82 in 2015, with substantial numbers reporting misuse and use disorders.

83 hes toward infectious diseases in people who misuse and/or are addicted to opioids and to concurrentl

84 . opioid crisis primarily target opioid use, misuse, and addiction, but because the opioid crisis inc

85 ch suggests that conduct disorder, substance misuse, and ADHD involve both unique forms of dysfunctio

86 ems such as accidental exposure, intentional misuse, and food and water contamination.

87 jor depression, generalised anxiety, alcohol misuse, and functional impairment.

88 unger age, female sex, unemployment, alcohol misuse, and greater opioid use in the ICU were significa

89 Coordinated mental health, substance misuse, and hepatitis treatment services increased HCV t

90 , frequent binge drinking, prescription drug misuse, and over-the-counter drug misuse).

91 h antisocial personality disorder, substance misuse, and suicide attempts were explained by factors o

92 ence perpetration, mental illness, substance misuse, and suicide ideation or attempt; number and type

93 ures of maternal opioid use, other substance misuse, and treatments or supports received.

94 e the prevalence of prescription opioid use, misuse, and use disorders and motivations for misuse amo

95 n the prevalence of prescription opioid use, misuse, and use disorders are limited.

96 Prescription opioid use, misuse, and use disorders.

97 tors shared between each disorder, substance misuse, and violence.

98 entions for psychiatric disorders, substance misuse, and violence.

99 (schizophrenia, bipolar disorder, substance misuse, and violent crime) were highly heritable (h(2)=5

100 Biology can be misused, and the risk of this causing widespread harm in

101 in close proximity; (2) frequent antibiotic misuse; and (3) insufficient drinking water, drainage an

102 Much of this misuse appears to be owing to the widespread, mistaken b

103 Although drugs of misuse appropriate ORs, conflicting reports indicate imm

104 intimate partner violence (IPV) and alcohol misuse are highly prevalent, and partner alcohol misuse

105 Gallstones and alcohol misuse are long-established risk factors, but several ne

106 Alcohol and cannabis misuse are related to impaired cognition.

107 n growth, soil degradation, and agrochemical misuse are significant challenges that agriculture must

108 Due to the potential misuse as a biothreat agent, abrin is in the focus of su

109 a first line treatment for ADHD and is also misused as a purported cognitive enhancer, yet its effec

110 hich may be associated with risk for alcohol misuse, as well as those which may occur as a result of

111 rug misuse high frequency peaked: rare or no misuse at any age, peak at age 18 years, peak at ages 19

112 or generalised anxiety disorder, and alcohol misuse at follow-up.

113 n for illicit drug use and prescription drug misuse, based in part on evidence of efficacy for unheal

114 evelopmental interval when continued alcohol misuse becomes more deviant.

115 utic approaches to prevent and treat alcohol misuse by understanding the molecular mechanisms of alco

116 the same mechanism is used by symbionts and misused by parasites to evade innate immune responses of

117 ow some specific toxicological data has been misused by those aiming to disingenuously influence publ

118 ale, and the secondary outcome, male alcohol misuse, by the Alcohol Use Disorders Identification Test

119 e to externalizing disorders such as alcohol misuse calls urgently for effective prevention and inter

120 ssing past-year frequency use for 8 commonly misused categories of substances appears to be a valid m

121 Substance misuse contributed most to the increased risk of BBV: af

122 unities come with privacy concerns, and data misuse could potentially lead to privacy infringement fo

123 y intervention programs for drug and alcohol misuse could substantially decrease the greatly elevated

124 In people with a prior history of opioid misuse, cues associated with previous drug intake can tr

125 Despite the continuing epidemic of opioid misuse, data on the prevalence of prescription opioid us

126 reatment for alcohol, cannabis, or hard drug misuse), date of death, primary cause of death, and educ

127 cipants; 1.84, 1.41-2.39, p<0.0001), alcohol misuse disorder (eight studies, 5040 participants; 1.44,

128 of both behaviours who also have a substance misuse disorder are at particularly high risk of dying f

129 ng disorders, personality disorders, alcohol misuse disorder, and substance misuse disorder.

130 ders, alcohol misuse disorder, and substance misuse disorder.

131 pants; 1.90, 1.39-2.61, p<0.0001), substance misuse disorders (11 studies, 5469 participants; 1.84, 1

132 reatment exist-comes from studies of alcohol misuse disorders or non-alcohol-related Wernicke-Korsako

133 Substance misuse disorders, particularly multiple drug use, was mo

134 disease especially in the absence of alcohol misuse disorders.

135 smucosal formulations can be associated with misuse, diversion, and nonadherence; these limitations m

136 potential association with subsequent opioid misuse, diversion, and the development of opioid use dis

137 a health-care setting also mitigates abuse, misuse, diversion, and unintentional exposure.

138 those which may occur as a result of alcohol misuse during adolescence and emerging adulthood.

139 The ongoing substance misuse epidemic in the United States is complex and dyna

140 but their addictive potential has sparked a misuse epidemic.

141 imary cause of this resistance is antibiotic misuse, especially routine inappropriate use of antibiot

142 h low socioeconomic status, drug and alcohol misuse, ethnic origin, and sex.

143 influences that were unrelated to substance misuse explained approximately a fifth (21%; 20-22%) of

144 ounger and had a higher incidence of alcohol misuse, fewer comorbidities, lower severity of illness,

145 improvement efforts suggest that antibiotic misuse for surgical disease is common.

146 s of a mental health condition and substance misuse for the respondent in 40% and 47% of cases, respe

147 cioeconomic status, education, and substance misuse) for BBV infection.

148 ty and the microbiome in relation to alcohol misuse- from binge drinking to addiction.

149 ounterfactual scenario in which persons with misuse had instead not misused opioids.

150 Prescription opioid misuse has become a leading cause of unintentional injur

151 ature suggest that toxicities may result and misuse has been underestimated, yet little information i

152 The current epidemic of prescription opioid misuse has increased scrutiny of postoperative opioid pr

153 with opioid misuse, similar persons without misuse have a reduced risk of suicidal behaviors.

154 The rates of cannabis misuse have been increasing.

155 AUD and aspects of alcohol misuse have been shown to overlap strongly with psychiat

156 was the age when past-year prescription drug misuse high frequency peaked: rare or no misuse at any a

157 for basic needs, combat experience, alcohol misuse, history of violence and arrests, and anger assoc

158 atient treatment for alcohol intoxication or misuse (HR = 1.98, 95% CI 1.76-2.21, p < 0.001).

159 lts suggest that chronic and current alcohol misuse in critically ill patients is associated with kid

160 ion to the loss of tax revenue, with alcohol misuse in England and Wales costing pound21 billion a ye

161 cesses linking avoidance tendency to alcohol misuse in punishment-sensitive drinkers.

162 rticle discusses the scope of the antibiotic misuse in surgery for surgical patients, and provides im

163 and reinforce the need to consider substance misuse in the context of ADHD in clinical interventions.

164 have been found to reduce substance use and misuse in those with elevated personality profiles.

165 nd hypothesis testing methods are frequently misused in clinical research.

166 eceived only limited attention and have been misused in many instances.

167 rdose deaths (largely attributable to opioid misuse) in the United States have grown exponentially fo

168 te to their (intended) benefit in preventing misuse, in these 11 European countries.

169 Alcohol misuse is a major public health problem originating from

170 se are highly prevalent, and partner alcohol misuse is a significant contributor to women's risk for

171 us, and any high-frequency prescription drug misuse is a strong risk factor for development of substa

172 Prescription opioid misuse is an ongoing crisis and a risk factor for inject

173 These findings suggest that opioid misuse is associated with greater odds of suicidal behav

174 Opioid misuse is at historically high levels in the United Stat

175 Reported prescription opioid misuse is common among adolescents and young adults and

176 Antibiotic use and misuse is driving drug resistance.

177 Inhalant (e.g., toluene) misuse is linked to behavioral and cognitive deficits in

178 Prescription drug misuse is most prevalent during young adulthood (ages 18

179 f suicidal behaviors, but opioid use without misuse is not.

180 Alcohol misuse is the leading cause of cirrhosis and the second

181 rate identification of patients with alcohol misuse may allow for the prevention of acute kidney inju

182 Propensity for alcohol misuse may be linked to an individuals' response to alco

183 id monitoring, and associated Current Opioid Misuse Measure (COMM) scores of PLHIV on COT.

184 diseases (men: 0.9; women: 1.4) and alcohol misuse (men: 2.8; women: 1.2).

185 nia) and one psychosocial outcome (substance misuse) met high quality standards.

186 , cognitive training intervention for opioid misuse, Mindfulness-Oriented Recovery Enhancement (MORE)

187 mprehensive account of the causes of alcohol misuse must accommodate individual differences in biolog

188 As commonly misused, null-hypothesis significance testing combines t

189 Accidental or intentional misuse of acetaminophen (APAP) is the leading cause of a

190 From 2004 to 2013, underuse and misuse of AET have decreased for patients with breast ca

191 d with long-term, daily clinical use or even misuse of amphetamine.

192 on developing rapid AST techniques to avoid misuse of antibiotics and provide effective treatment.

193 ading threat to global health because of the misuse of antibiotics and the rise in drug-resistant pat

194 The overuse and misuse of antibiotics has been identified as a significa

195 The misuse of antibiotics in health care and agriculture has

196 first century lifestyle practices, including misuse of antibiotics, dietary changes, and higher rates

197 athogenic bacteria, made worse by widespread misuse of antibiotics.

198 has been attributed to long-term, widespread misuse of antimonial drugs within the Indian private hea

199 threat and is often linked with overuse and misuse of clinical and veterinary chemotherapeutic agent

200 ntific community to identify and prevent the misuse of colour in science, and call for a proactive st

201 anium is necessary to minimize the potential misuse of highly enriched uranium in the world for nonpe

202 ine has the additional risk of diversion and misuse of medication.

203 re is work to be done to avoid the potential misuse of metrics like the JIF.

204 on with behavioral disinhibition and the use/misuse of nicotine, alcohol, and illicit drugs.

205 hosphate-stressed environments, reducing the misuse of nonrenewable fertilizers and their consequent

206 matically increased, including incidences of misuse of opioid drugs prescribed for pain control.

207 Control measures designed to prevent the misuse of opioid medicines can often unintentionally res

208 , which, in turn, will hopefully help lessen misuse of opioid pain medications and address the ongoin

209 lth interventions should focus on preventing misuse of opioids.

210 The use and misuse of P values has generated extensive debates.

211 Misuse of prescription and illegal opioids (e.g., morphi

212 Moreover, misuse of prescription and illicit narcotics has resulte

213 The diversion and misuse of prescription opioids along with increased use

214 Misuse of prescription opioids is a leading cause of pre

215 demonstrate critical issues arising from the misuse of principal component regression that result in

216 though futile treatment is acknowledged as a misuse of resources by many, no study has evaluated its

217 nsmission of infectious agents caused by the misuse of respiratory precautions.

218 Although misuse of social networking sites, particularly Twitter,

219 lways utilise consistent terminology and the misuse of some expressions in epidemiology is rife.

220 tractive non-invasive alternative to control misuse of such antibiotic and to ensure food safety by p

221 gens, and thus protect against the potential misuse of synthetic biology.

222 ed with AR determination to avoid overuse or misuse of the antibiotic.

223 an adequate analytical method to detect the misuse of the CRISPR/Cas system by athletes.

224 umerous studies in the past have illustrated misuse of the FOBT.

225 Anecdotal reports have surfaced concerning misuse of the HIV antiretroviral medication efavirenz ((

226 earch is needed to characterize the use (and misuse) of DTS.

227 with prescription opioid use, 12.5% reported misuse; of these, 16.7% reported a prescription opioid u

228 results characterize the effects of ketamine misuse on brain structure and function and highlight the

229 But regression is often misused on such data, ignoring statistical issues relate

230 core-weighted analyses, compared with opioid misuse, opioid use without misuse was associated with lo

231 in which persons with misuse had instead not misused opioids.

232 Among those misusing opioids, 55.7% obtained them from friends or re

233 f life, functional outcomes, adverse events, misuse or diversion, and risk assessment or mitigation.

234 Instead of misused or misinterpreted E-values, the authors recommen

235 n increased risk of any subsequent substance misuse outcomes (adjusted hazard ratio [aHR], 3.11; 95%

236 , which attenuated the risk of any substance misuse outcomes (aHR, 2.00; 95% CI, 1.82-2.19).

237 The risk of any substance misuse outcomes in individuals with TS/CTD was substanti

238 Substance misuse outcomes were defined as an ICD code of substance

239 etween ICD diagnoses of TS/CTD and substance misuse outcomes, accounting for psychiatric comorbidity

240 d with various types of subsequent substance misuse outcomes, independently of psychiatric comorbidit

241 at heightened risk for long-term opioid use, misuse, overdose, and death.

242 However, there is growing concerns about PPI misuse, overuse and abuse.

243 identify predictors of adolescent substance misuse, particularly if it can incorporate a wide range

244 lity (e.g., marijuana, alcohol, and caffeine misuse, perceived stress, and impulsive behavior).

245 ng for the discovery that adapted herbivores misuse plant secondary metabolites for multiple purposes

246 nto account that greater than half of youths misusing prescription opioids obtain these medications t

247 valence of additional drug abuse among those misusing prescription opioids.

248 ntal disorders, and programmes for substance misuse prevention and treatment.

249 0.91, 95% CI 0.40-2.05; p=0.82) or substance misuse problems (0.55, 0.27-1.17; p=0.12).

250 ly problems, and mental health and substance misuse problems.

251 istress, multiple physical symptoms, alcohol misuse, problems at home during and after deployment, an

252 ate substitution treatments reduce substance misuse relapse and possibly reoffending.

253 Those with opioid misuse reported high prevalence of prior cocaine (35.5%)

254 in decreasing prescription opioid abuse and misuse, research focusing on the development and evaluat

255 nts, we derived separate dimensional alcohol misuse scales and applied a proxy-phenotype study design

256 on of illicit drug use and prescription drug misuse screening and brief intervention.

257 Alcohol misuse screening and treatment was feasible in a primary

258 Compared with persons with opioid misuse, similar persons without misuse have a reduced ri

259 ar prevalence of prescription opioid use and misuse, sources of prescription opioids, and additional

260 Cocaine is one of the most commonly misused stimulant which could influence the central nerv

261 Exclusions included alcohol/drug misuse, suicidal plan or recent attempt, bipolar disorde

262 nding, 3.62; 95% CI, 3.41-3.84) and cannabis misuse (suicide attempt, 3.57; 95% CI, 3.25-3.92; violen

263 gh shares of excess mortality due to alcohol misuse, suicide, and accidents.

264 EHV1 infection of T lymphocytes and how EHV1 misuses T lymphocytes as a vehicle to reach the endothel

265 els of current and future adolescent alcohol misuse that incorporate brain structure and function, in

266 nt to know what would happen if a researcher misused their health information; fewer (51%, CI: 47%-55

267 who are prescribed opioids for chronic pain misuse them, and 5 to 10% develop an opioid use disorder

268 ed prescription opioids; 11.5 million (4.7%) misused them; and 1.9 million (0.8%) had a use disorder.

269 underlying individual differences in alcohol misuse, these models shed light on the aetiology of alco

270 ributions of human and veterinary antibiotic misuse to this crisis are well-recognized, environmental

271 determinants of health (SDHs, including drug misuse, tobacco smoking and alcohol), and TB, taking int

272 rculosis in England, including through drugs misuse, tobacco smoking, and homelessness.

273 Prescription drug misuse trajectories are heterogeneous, and any high-freq

274 We aimed to identify prescription drug misuse trajectories for three drug classes (opioids, sti

275 Prescription drug misuse trajectories were all associated with significant

276 Five prescription drug misuse trajectories were identified and the defining cha

277 Similar prescription drug misuse trajectories were identified for each prescriptio

278 ood, especially later-peak prescription drug misuse trajectories.

279 associated with high-risk prescription drug misuse trajectories.

280 The later peak misuse trajectory for sedatives and tranquilisers creste

281 the high-risk latest peak prescription drug misuse trajectory included high school heavy drinking, c

282 Prevalence of opioid use, misuse, use disorder, and additional substance use were

283 pared with opioid misuse, opioid use without misuse was associated with lower odds of suicidal ideati

284 95% CI 3.9%-26.3%), while alcohol/substance misuse was commonly reported by adults (12.9%, 95% CI 9.

285 rder (PTSD), depression, anxiety, or alcohol misuse was effective.

286 Opioid misuse was reported by 1,050 adolescents (3.8%; 95% CI 3

287 Alcohol misuse was the highest risk factor for DALYs (7.0% overa

288 The most commonly reported motivation for misuse was to relieve physical pain (63.4%).

289 he COMM score, a measure of potential opioid misuse, was high.

290 some other health outcomes including alcohol misuse, well-being, change in haemoglobin A1c (HbA1c), a

291 some other health outcomes including alcohol misuse, well-being, change in HbA1c, and smoking cessati

292 behaviour, anxiety disorders, and substance misuse were identified in 19% (1%-36%) and 11% (7%-16%)

293 nia) and one psychosocial outcome (substance misuse) were of a high quality.

294 oking, marijuana use, poly-prescription drug misuse, white race, and not completing a 4-year universi

295 lated past-year prevalence of opioid use and misuse with or without use disorder, sources of prescrip

296 We assessed associations of opioid use and misuse with suicidal ideation, suicide plans, and suicid

297 rne viruses (including risks related to drug misuse) with people who have serious mental illness, as

298 sing opioids were more likely to have opioid misuse without use disorder compared with females (23.2%

299 Targeting of comorbid substance misuse would have particular effect on reduction of BBV

300 enetic engineering attribution', would deter misuse, yet is still considered unsolved.