ライフサイエンスコーパス: mitis

1 China was caused by a toxigenic clone of S. mitis.

2 regions contribute to platelet binding by S. mitis.

3 understanding the population structure of S. mitis.

4 a protective function for the capsule in S. mitis.

5 aphylococcus and the other for Streptococcus mitis.

6 both platelet binding and aggregation by S. mitis.

7 of Selenomonas, Neisseria, and Streptococcus mitis.

8 the mitilysin gene from seven isolates of S. mitis.

9 els of bacteremia caused predominantly by S. mitis.

10 ver, hybridized to DNA from S. oralis and S. mitis.

11 cus gordonii Blackburn, 10558, Streptococcus mitis 10712, 903, Streptococcus oralis 10557, 9811, and

12 Streptococcus spp. were found, including S. mitis (25 strains, 50.0% of 50); currently unnamed Strep

13 Recently, Streptococcus mitis, a human commensal and a close relative of S. pneu

14 Streptococcus mitis, a human commensal, acts as a genetic diversity re

15 mutant showed that the capsule protected S. mitis against phagocytosis by RAW 264.7 macrophages.

16 typing and strain clustering schemes for S. mitis allow for the integration of new strain data, are

17 Streptococcus mitis, although not previously reported as a cause of pn

18 obe not only to image the permeability of S. mitis and C. matruchotii membranes to tetraethylammonium

19 ) or increased growth (such as Streptococcus mitis and Corynebacterium matruchotii) across anthropome

20 he human supragingival plaque, Streptococcus mitis and Corynebacterium matruchotii, to elucidate thei

21 antigens in certain strains of Streptococcus mitis and Eikenella corrodens.

22 No differences in the tox regions between mitis and gravis biotype strains were observed.

23 oxigenic Corynebacterium diphtheriae of both mitis and gravis biotypes, showing that the organism is

24 s with various Streptococcus spp., including mitis and mutans group streptococci.

25 ups demonstrated increased proportions of S. mitis and S. oralis by day 1.

26 eumococci and the closely related species S. mitis and S. oralis, showing up to 10.4% nucleotide dive

27 han to most CSPs previously reported from S. mitis and S. oralis, suggesting that these particular or

28 ae, isolates phenotypically identified as S. mitis and S. oralis, which included isolates previously

29 l CSPs from disease-associated strains of S. mitis and S. oralis.

30 shared by eight species in the Streptococcus mitis and Streptococcus anginosus groups, is regulated b

31 bits natural transformation of Streptococcus mitis and Streptococcus gordonii.

32 s particularly problematic for Streptococcus mitis and Streptococcus oralis isolates.

33 ted oral streptococcal species Streptococcus mitis and Streptococcus oralis on the basis of three dif

34 Together, Streptococcus mitis and Streptococcus oralis were significantly more l

35 enetic exchange is known to occur between S. mitis and Streptococcus pneumoniae, this finding may hav

36 Eight species including Streptococcus mitis and Streptococcus species HOT070 were prevalent in

37 ccus pseudopneumoniae, 12 were Streptococcus mitis, and 1 were Streptococcus oralis.

38 , Streptococcus parasanguinis, Streptococcus mitis, and Corynebacterium pseudogenitalium.

39 ns of S. gordonii, S. sanguis, S. mutans, S. mitis, and S. oralis but only weakly by S. salivarius.

40 characterized isolates of S. pneumoniae, S. mitis, and S. oralis.

41 killed Pseudomonas aeruginosa, Streptococcus mitis, and Streptococcus pneumoniae in a dose-dependent

42 S. mitis appear to release mitilysin extracellularly.

43 ity and biology, but schemes specific for S. mitis are not currently available.

44 of the competence regulon QS circuitry in S. mitis are yet to be explored.

45 the effects temporal QS modulation has on S. mitis as it inhabits its natural niche.

46 ncorrect identification (e.g., Streptococcus mitis), as did matrix-assisted laser desorption ionizati

47 The organism was identified as Streptococcus mitis based on biochemical and 16S rRNA sequence analyse

48 of multiple transposases in a Streptococcus mitis biofilm when the periodontopathogen P. gingivalis

49 , and dtxR type 1 was characteristic for the mitis biotype strains.

50 rains (62 of the gravis biotype and 4 of the mitis biotype) isolated during the Georgian diphtheria e

51 the pioneer oral streptococci Streptococcus mitis biovar 1 and Streptococcus oralis, the late oral c

52 from Streptococcus oralis and Streptococcus mitis biovar 1 strains but were cleaved to various degre

53 the components in unripe calamondin (Citrus mitis Blanco) peel were investigated by performing bioas

54 ds of mature and immature calamondin (Citrus mitis Blanco) peel were investigated.

55 ere we use whole genome sequencing of 129 S. mitis bloodstream infection (BSI) isolates collected bet

56 d genetically are most closely related to S. mitis but which harbor genes encoding the virulence dete

57 ng Cercopithecus sp (C.ascanius, C.cephus, C.mitis, C.nictitans, C.neglectus, C.pogonias), Cercocebus

58 we hypothesize that P. gingivalis induces S. mitis cell death by an unknown mechanism, shaping the or

59 ble new insights into the epidemiology of S. mitis colonization, disease and transmission.

60 h the pneumococcus ComD receptors and the S. mitis ComD-2 receptor with high potencies.

61 In a multivariate analysis, S. aureus, S. mitis, Corynebacterium accolens, and bacilli were signif

62 re, our analysis revealed that the native S. mitis CSP signal can modulate QS response in S. pneumoni

63 demonstrating that P. gingivalis induces S. mitis death and DNA fragmentation in an in vitro biofilm

64 h concordance (100%), capturing extensive S. mitis diversity with strains assigned to multiple unique

65 mmon among the strains of S. gordonii and S. mitis examined.

66 the toxic effect of E. corrodens extract S. mitis extracts contained a single, strongly reactive ant

67 et of oral microbes, including Streptococcus mitis, Gemella haemolysans, and, most prominently, Strep

68 Several genera such as Streptococcus mitis, Gemella parahaemolysans, Lactococcus lactis, and

69 tified extensive within- and between-host S. mitis genetic diversity among isolates sampled from a co

70 majority of episodes were categorized in the Mitis group (348 episodes; 40%), followed by the Pyogeni

71 ity was produced only by some members of the mitis group (Streptococcus mitis, Streptococcus oralis,

72 Eighty-four species verified mitis group isolates were subjected to our bile solubili

73 In general, Streptococcus mitis group organisms are resistant to more antimicrobia

74 ptococcus pneumoniae from nonpneumococcal S. mitis group species.

75 neumoniae strains but misidentified 13 other mitis group strains.

76 pseudopneumoniae but misidentified 16 other mitis group strains.

77 The mitis group streptococci (MGS) are widespread in the ora

78 ntiated S. pneumoniae from all but one other mitis group streptococci (one S. mitis isolate generated

79 ation of Streptococcus pneumoniae from other mitis group streptococci, including differentiation of S

80 communities rich in Candida are also rich in mitis group Streptococci,a community pattern associated

81 Streptococcus gordonii (mitis group) has been shown to bind avidly to C. albican

82 newly described member of the Streptococcus mitis group.

83 ecies Streptococcus mutans and Streptococcus mitis, however, lactoferrin containing Lys at position 2

84 Our findings suggest that S. mitis in patients with clinically diagnosed IE is not pr

85 hting the accidental pathogenic nature of S. mitis in patients with clinically diagnosed IE.

86 te the competence regulon QS circuitry in S. mitis, including confirming the identity of the native C

87 l from the chamber compared to cells from S. mitis-infected chambers.

88 Streptococcus mitis is a common oral commensal and an opportunistic pa

89 Streptococcus mitis is a leading cause of infective endocarditis (IE).

90 iology and pathogenicity of IE-associated S. mitis is hampered by low IE incidence.

91 These results suggest that S. mitis is the most common cause of viridans streptococcal

92 t one other mitis group streptococci (one S. mitis isolate generated an OD-value above 2.1).

93 tes did fall into a well-separated group, S. mitis isolates did not cluster into a well-separated gro

94 itilysin, in a small number of Streptococcus mitis isolates.

95 cell wall polysaccharide from Streptococcus mitis J22 are correlated with individual glycosidic dihe

96 e show that while the polysaccharide from S. mitis J22 is flexible, requiring multiple conformations,

97 i and Endangered golden guenon Cercopithecus mitis kandti.

98 oral streptococci, including isolates of S. mitis known to possess pneumolysin and autolysin.

99 tralization assay results, one isolate of S. mitis may produce a further hemolytic toxin in addition

100 rom ten JEB patients (JEB gravis, n = 4; JEB mitis, n = 3; JEB plus pyloric atresia [JEB/PA], n = 3)

101 7.7 years) from an outbreak of Streptococcus mitis/oralis endophthalmitis after bevacizumab injection

102 S. mitis/oralis endophthalmitis is a devastating complicati

103 gordonii, S sanguinis, S gallolyticus, and S mitis/oralis having the highest IE prevalence and the hi

104 presence of a common strain of Streptococcus mitis/oralis in vitreous specimens and 7 unused syringes

105 olyticus odds ratio (OR) 31.0 (18.8-51.1), S mitis/oralis OR 31.6 (19.8-50.5), S sanguinis OR 59.1 (3

106 vitreal bevacizumab injection, Streptococcus mitis/oralis was cultured from the majority of patients

107 ular testing confirmed a common strain of S. mitis/oralis.

108 affected patients also were positive for S. mitis/oralis.

109 10 patients were positive for Streptococcus mitis/oralis.

110 eptococcus viridans (P = .46), Streptococcus mitis (P = .83), and Enterococcus faecalis (P = .46).

111 nts, and 13 of those cases were caused by S. mitis (P = 0.007).

112 bacterium acnes phage PA6, and Streptococcus mitis phage SM1.

113 egulon QS circuitry in initiating various S. mitis phenotypes.

114 The oral streptococcal group (mitis phylogenetic group) currently consists of nine rec

115 S. mitis possesses a typical comABCDE competence regulon QS

116 e were followed by a switch to Streptococcus mitis predominance after 3 months of age.

117 Under such conditions, S. mitis resistance to clearance could be enhanced by capsu

118 ogenic oral bacterial species, Streptococcus mitis, resulted in well-controlled infection, with bacte

119 Oral taxon 44, while Streptococcus mitis, Rothia mucilaginosa and Haemophilus parainfluenza

120 gainst challenge by the oral streptococci S. mitis, S. mutans, and S. salivarius.

121 ion observed for other species, including S. mitis, S. oralis, and S. pseudopneumoniae.

122 We found that S. mitis, S. oralis, and S. sanguis, as well as oral actino

123 SSA-3 hybridized to DNA from S. gordonii, S. mitis, S. oralis, S. parasanguinis, and S. vestibularis.

124 The LLY gene was identified in strains of S. mitis, S. pneumoniae, and Streptococcus pseudopneumoniae

125 icantly decreased included the Streptococcus mitis-S. pneumoniae-S. infantis group, Corynebacterium m

126 ks, and 6 mos, and were cultured on modified Mitis Salivarius agar for mutans streptococci and on blo

127 occi (MS) on mitis-salivarius-bacitracin and mitis-salivarius agar; (2) non-mutans streptococci (non-

128 gar; (2) non-mutans streptococci (non-MS) on mitis-salivarius agar; (3) organisms that were categoriz

129 lood agar or the predominant non-MS flora on mitis-salivarius agar; and (4) iodophilic polysaccharide

130 bjects were: (1) mutans streptococci (MS) on mitis-salivarius-bacitracin and mitis-salivarius agar; (

131 ne the MLST scheme and derived the global S. mitis sequence clusters using the PopPUNK clustering alg

132 Platelet binding by Streptococcus mitis SF100 is mediated in part by a lysin encoded by th

133 atelet aggregation factor from Streptococcus mitis (Sm-hPAF) was characterized and shown to be a func

134 s genus was mainly composed of Streptococcus mitis species.

135 The oral commensal S. mitis spp associates with preserved lung function and im

136 opneumoniae strains but misidentified one S. mitis strain as S. pseudopneumoniae, and fastANI differe

137 actate concentration produced by a single S. mitis strain at a rate of 2.7 x 10(-4) cm/s, and (3) a l

138 This effect was enhanced in the S. mitis strain expressing the S. pneumoniae capsule, which

139 Platelet binding by Streptococcus mitis strain SF100 (an endocarditis isolate) was recentl

140 d a Tn916deltaE-derived mutant library of S. mitis strain SF100 for reduced binding to human platelet

141 Platelet binding by Streptococcus mitis strain SF100 is mediated in part by two bacterioph

142 e prophage-encoded proteins of Streptococcus mitis strain SF100 that mediate binding to human platele

143 . mitis strains (28.0%, 7/25) and not non-S. mitis strains (0/25) (P = 0.004).

144 MIC, 4 to 12 mug/ml) was noted only among S. mitis strains (28.0%, 7/25) and not non-S. mitis strains

145 the antigenic profile, we found that some S. mitis strains (P066 and P107) reacted with both serotype

146 When the direct binding of S. mitis strains SF100 and PS344 to immobilized ganglioside

147 Significantly more S. mitis strains than non-S. mitis strains were resistant t

148 nificantly more S. mitis strains than non-S. mitis strains were resistant to fluoroquinolones and to

149 iae strains, 59 S. pneumoniae strains, 22 S. mitis strains, 24 S. oralis strains, 6 S. infantis strai

150 iae, Streptococcus oralis, and Streptococcus mitis strains.

151 lassification schemes within members of the "mitis" streptococcal group.

152 gher counts and proportions of Streptococcus mitis, Streptococcus oralis, and Streptococcus mutans, w

153 guinis, Abiotrophia defectiva, Streptococcus mitis, Streptococcus oralis, and Streptococcus sanguinis

154 me members of the mitis group (Streptococcus mitis, Streptococcus oralis, Streptococcus gordonii, Str

155 erase chain reaction to detect Streptococcus mitis, Streptococcus sobrinus, Streptococcus mutans, Str

156 5 clinical blood cultures with Streptococcus mitis/Streptococcus oralis and 1/3 blood cultures spiked

157 S. mitis survival in horse blood or in a mouse model of bac

158 Since SM1 is the first prophage of S. mitis that has been identified and because of the possib

159 8) also inhibited the binding in vitro of S. mitis to human fibrinogen and platelets.

160 The direct binding of Streptococcus mitis to human platelets is mediated in part by two prot

161 life cycle, lysin mediates the binding of S. mitis to human platelets via its interaction with fibrin

162 pblA and pblB mediate the attachment of S. mitis to platelets and play a significant role in S. mit

163 lpA (5 to 100 microg/ml), from Streptococcus mitis, to induce the production of proinflammatory cytok

164 hen species (Evernia mesomorpha and Cladonia mitis), two vascular plant species (Rhododendron groenla

165 A recessively inherited variant, the mitis type of DEB (M-RDEB), is characterized by a mild p

166 showed higher rates of survival than the S. mitis type strain or the capsule-switching mutant, excep

167 In this study, the S. mitis type strain switched capsule by acquisition of the

168 defined sequence clusters or lineages of S. mitis using a comprehensive global data set of 322 genom

169 ing in either a deficiency (in the nonlethal mitis variety) or a complete absence (in lethal Herlitz-

170 eslundii, Lactobacillus casei, Streptococcus mitis, Veillonella parvula, and Fusobacterium nucleatum)

171 platelets and play a significant role in S. mitis virulence in the endocardium, but have never previ

172 at mediate platelet binding by Streptococcus mitis, we screened a Tn916deltaE-derived mutant library

173 All 8 isolates of Streptococcus mitis were misidentified as being Streptococcus pneumoni

174 o HL60 cells, whereas similar extracts of S. mitis were nontoxic.

175 cells in chambers from mice infected with S. mitis were PI positive (apoptotic) or negative (live).

176 cterium diphtheriae strains; six were biovar mitis, which were associated with recent travel abroad.

177 w high genetic diversity of IE-associated S. mitis with virtually all isolates belonging to distinct

178 ng oral streptococci including Streptococcus mitis (with the exception of 1 of 14 strains), Streptoco