ライフサイエンスコーパス: mitochondrial biogenesis

1 was decreased, likely secondary to decreased mitochondrial biogenesis.

2 xidative stress, and apoptosis and increased mitochondrial biogenesis.

3 supporting a key role for Nrf2 in control of mitochondrial biogenesis.

4 min inhibits the opening of mPTP and induces mitochondrial biogenesis.

5 tors), and to change cell energetics through mitochondrial biogenesis.

6 to control BAT-selective gene expression and mitochondrial biogenesis.

7 a key regulator of antioxidant response and mitochondrial biogenesis.

8 nstrated that cryptolepine treatment reduced mitochondrial biogenesis.

9 ls resulted in reduced autophagy and reduced mitochondrial biogenesis.

10 ription of PGC-1alpha, a master regulator of mitochondrial biogenesis.

11 ed reduced expression of PGC-1beta, PRC, and mitochondrial biogenesis.

12 of mitochondrial dynamics and a reduction in mitochondrial biogenesis.

13 sis, foetal gene reprogramming, and impaired mitochondrial biogenesis.

14 increased fatty acid oxidation and enhanced mitochondrial biogenesis.

15 s an energy-sensing enzyme known to modulate mitochondrial biogenesis.

16 the role of labile heme in the regulation of mitochondrial biogenesis.

17 ation of BSM cells in asthmatic patients and mitochondrial biogenesis.

18 roliferation and has also been implicated in mitochondrial biogenesis.

19 mitochondrial fission-fusion, mitophagy, and mitochondrial biogenesis.

20 he preprotein import reactions essential for mitochondrial biogenesis.

21 d-induced BAT expansion and severely impairs mitochondrial biogenesis.

22 muscle mitochondrial function by increasing mitochondrial biogenesis.

23 s on muscle function, including induction of mitochondrial biogenesis.

24 mitochondrial oxygen consumption and induced mitochondrial biogenesis.

25 abolic genes, oxidative phosphorylation, and mitochondrial biogenesis.

26 pensatory mechanism is indeed an increase in mitochondrial biogenesis.

27 lin enhances physical endurance by promoting mitochondrial biogenesis.

28 oxia in kidney epithelial cells by improving mitochondrial biogenesis.

29 cond step mTOR activation leads to increased mitochondrial biogenesis.

30 o been shown to up-regulate ROS by promoting mitochondrial biogenesis.

31 eled an increase in autophagy, mitophagy and mitochondrial biogenesis.

32 TFAM, TFB1M, and TFB2M, resulting in reduced mitochondrial biogenesis.

33 , plays a critical role in the regulation of mitochondrial biogenesis.

34 tional program, which has been implicated in mitochondrial biogenesis.

35 tivate their own transcriptional program for mitochondrial biogenesis.

36 no further changes seen across indicators of mitochondrial biogenesis.

37 ndent matrix processes that are critical for mitochondrial-biogenesis.

38 ignaling was sufficient to promote beta-cell mitochondrial biogenesis, a shift to oxidative metabolis

39 4) copy number, intracellular ATP level, and mitochondrial biogenesis activators (TFAM, PGC-1alpha an

40 at enhancing Parkin-associated mitophagy and mitochondrial biogenesis after infarction is a viable ta

41 of EF-Tu and induction of genes involved in mitochondrial biogenesis, along with increased expressio

42 gnaling cascades such as mTor that influence mitochondrial biogenesis also affect ciliogenesis, and c

43 tional studies demonstrate that PK2 promotes mitochondrial biogenesis and activates ERK and Akt survi

44 n rodent models, exercise training increases mitochondrial biogenesis and activity in both these adip

45 ing degrees, owing to its ability to enhance mitochondrial biogenesis and activity in megakaryocytes

46 Our study demonstrates induction of mitochondrial biogenesis and aerobic glycolysis in respo

47 short-term stress responses, an increase in mitochondrial biogenesis and an increase in some catabol

48 ing glycolytic-to-oxidative myofiber switch, mitochondrial biogenesis and angiogenesis in lean mice.

49 ssion of the AMPK cascade genes, involved in mitochondrial biogenesis and antioxidant defences, was a

50 lpha) via in vivo transfection would promote mitochondrial biogenesis and antioxidant defense, thus a

51 PRC) has a dual function in growth-regulated mitochondrial biogenesis and as a sensor of metabolic st

52 otein kinase (AMPK) signaling and stimulated mitochondrial biogenesis and autophagy to maintain energ

53 dation and are involved in the regulation of mitochondrial biogenesis and bioenergetics.

54 drial interface and acts as a checkpoint for mitochondrial biogenesis and bioenergetics.

55 Moreover, markers of mitochondrial biogenesis and cardiolipin content were st

56 quently, we found that labile heme regulates mitochondrial biogenesis and cell growth.

57 ted by cocaine inducing energy sensor AMPKs, mitochondrial biogenesis and chromatin remodeling comple

58 al mechanism, as FXN-dependent deficiency in mitochondrial biogenesis and consequent mitochondrial bi

59 ivator (PGC)-1alpha is a master regulator of mitochondrial biogenesis and controls metabolism by coor

60 mitochondria, and all external regulators of mitochondrial biogenesis and dynamics can influence the

61 y and expression levels of genes involved in mitochondrial biogenesis and dynamics in the prelimbic m

62 empt to recover OXPHOS activity by promoting mitochondrial biogenesis and dynamics.

63 crobiota-metabolites-brain axis: IF enhances mitochondrial biogenesis and energy metabolism gene expr

64 their coregulators in the dynamic control of mitochondrial biogenesis and energy metabolism in the no

65 d an adaptive stress response that activated mitochondrial biogenesis and enhanced mitochondrial fatt

66 eatment of aged CPCs also failed to increase mitochondrial biogenesis and expression of the mitochond

67 ve strategy to induce adaptations related to mitochondrial biogenesis and fat oxidation.

68 eved by delaying cell division and enhancing mitochondrial biogenesis and fatty acid oxidation, witho

69 uman liver via CYP26 inhibition may increase mitochondrial biogenesis and fatty acidbeta-oxidation an

70 ome wide regulation of genes responsible for mitochondrial biogenesis and function by Galpha(13) in o

71 Mitochondrial biogenesis and function defects in these c

72 thyl fumarate (DMF) dose-dependently induces mitochondrial biogenesis and function dosed to cells in

73 ed differentiation place variable demands on mitochondrial biogenesis and function for cell types wit

74 gs identify 5-HT as an upstream regulator of mitochondrial biogenesis and function in cortical neuron

75 s required to mediate the effects of 5-HT on mitochondrial biogenesis and function in cortical neuron

76 activator pyrroloquinoline quinone enhances mitochondrial biogenesis and function in lung endotheliu

77 ort a transcriptional program that represses mitochondrial biogenesis and function in lysosomal stora

78 However, the factors that influence mitochondrial biogenesis and function in neurons remain

79 role for serotonin (5-HT) as a regulator of mitochondrial biogenesis and function in rodent cortical

80 nd signaling networks that serve to regulate mitochondrial biogenesis and function in the mammalian h

81 on of 5-HT neurons also resulted in enhanced mitochondrial biogenesis and function in vivo.

82 NA (mtDNA) mutations leads to alterations of mitochondrial biogenesis and function that might produce

83 Moreover, the genes involved in mitochondrial biogenesis and function were significantly

84 ranscription factor PPAR-gamma that controls mitochondrial biogenesis and function, has a pivotal rol

85 nown transcriptional regulators of postnatal mitochondrial biogenesis and function, serve a role in t

86 elow toxic levels, hydrogen sulfide promotes mitochondrial biogenesis and function, thereby conferrin

87 rilipin 5 (PLIN5), which is known to enhance mitochondrial biogenesis and function, to be a fatty-aci

88 PGC-1alpha is a master regulator of mitochondrial biogenesis and function.

89 duction of "adult" AChRepsilon, and impaired mitochondrial biogenesis and function.

90 ption factor A (TFAM) that normally supports mitochondrial biogenesis and functional recovery.

91 functional analyses revealed an increase of mitochondrial biogenesis and global translational rate i

92 equence, p53 is unable to slow the increased mitochondrial biogenesis and hence the subsequent increa

93 elta, PGC-1alpha signaling pathway, enhanced mitochondrial biogenesis and improved antioxidant defens

94 ar nucleus of hypertensive rats by promoting mitochondrial biogenesis and improving mitochondrial dyn

95 Aged CPCs fail to activate mitochondrial biogenesis and increase proteins involved

96 F contributes to neurotoxicity by modulating mitochondrial biogenesis and inflammatory pathways.

97 demonstrates cellular mechanisms that couple mitochondrial biogenesis and inheritance with oocyte dev

98 pability of metformin to stimulate placental mitochondrial biogenesis and inhibit the aberrant epigen

99 muscle cell signalling pathways (regulating mitochondrial biogenesis and lipid metabolism) and indic

100 in-related protein 1 (Drp1) is necessary for mitochondrial biogenesis and maintenance of healthy mito

101 ystem is the result of a remarkable surge in mitochondrial biogenesis and maturation during the fetal

102 This regulation in turn inhibits mitochondrial biogenesis and metabolic activity and prot

103 Here we show that shear stress favours mitochondrial biogenesis and metabolic reprogramming to

104 We identified four proteins implicated in mitochondrial biogenesis and metabolism regulation as ca

105 both Nox4 and Nrf2 in counter-regulation of mitochondrial biogenesis and metabolism.

106 Our results point to the conclusion that mitochondrial biogenesis and mitochondrial dysfunction i

107 nd, most notably, age-related impairments in mitochondrial biogenesis and mitochondrial function.

108 We conclude that although increase in mitochondrial biogenesis and other pathways may contribu

109 coactivator-1alpha (PGC-1a), which mediates mitochondrial biogenesis and oxidative capacity in skele

110 ngs suggest that Perm1 selectively regulates mitochondrial biogenesis and oxidative function, and imp

111 promotes transcription of genes that mediate mitochondrial biogenesis and oxidative function.

112 Lipolysis promotes mitochondrial biogenesis and oxidative metabolism via a

113 alpha (PGC-1alpha) plays a critical role in mitochondrial biogenesis and oxidative metabolism.

114 Mitochondrial biogenesis and oxidative phosphorylation p

115 ains mitochondrial homeostasis by modulating mitochondrial biogenesis and PINK-1/DCT-1-dependent mito

116 esults indicate that TGR5 activation induces mitochondrial biogenesis and prevents renal oxidative st

117 cluding metabolic alterations and changes in mitochondrial biogenesis and protein homeostasis.

118 Indeed, mitochondrial biogenesis and quality control are often u

119 s improved by exercise training through both mitochondrial biogenesis and removal of damaged/dysfunct

120 Regulation of mitochondrial biogenesis and respiration is a complex pr

121 tection from oxidative stress, necessary for mitochondrial biogenesis and respiration upon activation

122 fferentiation of murine brown adipocytes and mitochondrial biogenesis and respiration, leading to att

123 ugh the transcriptional programs that govern mitochondrial biogenesis and respiratory function are we

124 5, we observed transcriptional activation of mitochondrial biogenesis and restoration of mitochondria

125 associated alterations on energy metabolism, mitochondrial biogenesis and restores mitochondrial memb

126 ferentiation of CD8(+) T cells and increased mitochondrial biogenesis and spare respiratory capacity

127 ll viability by reducing apoptosis, inducing mitochondrial biogenesis and strongly reducing the level

128 genes related to the mitochondrial dynamics, mitochondrial biogenesis and synapses from 6-month-old D

129 aintains mitochondrial dynamics and enhances mitochondrial biogenesis and synaptic activity in APP mi

130 d maintains mitochondrial dynamics, enhances mitochondrial biogenesis and synaptic activity in APP mi

131 d maintains mitochondrial dynamics, enhances mitochondrial biogenesis and synaptic activity in Tau mi

132 hondrial damage is reversed by activation of mitochondrial biogenesis and that gene transcripts measu

133 C-1 transcriptional coactivators, drivers of mitochondrial biogenesis and the browning program.

134 y metabolism, fatty acid beta-oxidation, and mitochondrial biogenesis and their key regulator Ppargc1

135 efect, suggesting that vitamin B12 regulates mitochondrial biogenesis and then affects mitochondrial

136 ipose tissue and suppression of lipogenesis, mitochondrial biogenesis and thermogenesis.

137 ion despite MAPKi treatment showed increased mitochondrial biogenesis and tumor bioenergetics.

138 ng cancer cell viability by stimulating both mitochondrial biogenesis and turnover through BNIP3 indu

139 energetics support transformation, including mitochondrial biogenesis and turnover, fission and fusio

140 eeds to be confirmed is blunting of reactive mitochondrial biogenesis and unfolded protein response.

141 lpha (PGC1alpha) is the primary regulator of mitochondrial biogenesis and was recently found to be hi

142 Germline loss triggers H2S production, mitochondrial biogenesis, and a dynamic pattern of ROS i

143 d in postnatal premature mortality, impaired mitochondrial biogenesis, and altered mitochondrial matu

144 of its classic targets, such as metabolism, mitochondrial biogenesis, and cellular respiration in th

145 traction speed), but not endurance capacity, mitochondrial biogenesis, and fiber type transformation.

146 , increases the expression of PGC-1alpha and mitochondrial biogenesis, and improves phenotype and sur

147 Decreased ovarian reserve, dysregulation of mitochondrial biogenesis, and increased lipid peroxidati

148 enes required for oxidative phosphorylation, mitochondrial biogenesis, and maintenance.

149 rough the inhibition of PI3K-mTOR signaling, mitochondrial biogenesis, and metabolic activity.

150 Impaired exercise tolerance, mitochondrial biogenesis, and muscle fiber maintenance i

151 chitecture, excitation-contraction coupling, mitochondrial biogenesis, and oxidative phosphorylation

152 he increased PGC1alpha and UCP1 expressions, mitochondrial biogenesis, and oxygen consumption.

153 n and matrix and increased levels of fusion, mitochondrial biogenesis, and synaptic genes were found

154 nd PPARdeltarevealed that the enhancement of mitochondrial biogenesis andbeta-oxidation byatRA requir

155 r-1alpha (PGC-1alpha), a master regulator of mitochondrial biogenesis, antioxidant defense, and cellu

156 include cell cycle progression, senescence, mitochondrial biogenesis, apoptosis, and glutaminolysis.

157 Telomere shortening and alterations of mitochondrial biogenesis are involved in cellular aging.

158 ally, primary cilium-dependent lipophagy and mitochondrial biogenesis are required to support energy-

159 rvations suggest that lipid peroxidation and mitochondrial biogenesis are the key intracellular pathw

160 rvations suggest that lipid peroxidation and mitochondrial biogenesis are the key intracellular pathw

161 tein response, additional roles for ClpXP in mitochondrial biogenesis are unclear.

162 model of ED-related behaviors and identifies mitochondrial biogenesis as a potential molecular pathwa

163 il, a phosphodiesterase 5 inhibitor, induced mitochondrial biogenesis as measured by increased uncoup

164 mitochondrial myopathies, with induction of mitochondrial biogenesis as the suggested main mechanism

165 ogical approaches resulted in stimulation of mitochondrial biogenesis, as evidenced by elevated mitoc

166 This holistic view places mitochondrial biogenesis at a central position of the ce

167 initiates signaling to provoke increases in mitochondrial biogenesis, balanced by the onset of organ

168 cise training has long been known to promote mitochondrial biogenesis, but recent work has demonstrat

169 ghlight a new mechanism in the regulation of mitochondrial biogenesis by cellular metabolites.

170 ies of p53 such as apoptosis but retains its mitochondrial biogenesis capacity, showed preservation o

171 at Pparg is critical in urothelial cells for mitochondrial biogenesis, cellular differentiation and r

172 pathway enzymes and the enhanced autophagy, mitochondrial biogenesis, collagen deposition and endopl

173 ression of transcription factors involved in mitochondrial biogenesis compared to a healthy control c

174 ression of transcription factors involved in mitochondrial biogenesis compared to HC.

175 al, adaptive response in muscle that invokes mitochondrial biogenesis, compensatory peroxisomal fat o

176 regulation of myogenesis and a downregulated mitochondrial biogenesis contribute to pathologic change

177 e response (DDR) towards PGC-1beta-dependent mitochondrial biogenesis, contributing to aROS-mediated

178 ctor (NRF)-1, a key transcription factor for mitochondrial biogenesis, cooperated with DNA methylatio

179 ns may also have translational potential, as mitochondrial biogenesis could now be followed as a clin

180 The induction of mitochondrial biogenesis could potentially alleviate mit

181 Our study establishes mitochondrial biogenesis, coupled with aberrant tumor bi

182 cultured with high glucose, INT-777 induced mitochondrial biogenesis, decreased oxidative stress, an

183 ted melanoma cells with a low basal level of mitochondrial biogenesis depend on this process to survi

184 scriptome analysis revealed the induction of mitochondrial biogenesis, down-regulation of diabetes-re

185 might be essential for mtDNA replication and mitochondrial biogenesis during oogenesis.

186 ibitor 1 (Mdivi-1) on mitochondrial fission, mitochondrial biogenesis, electron transport activities

187 At night retinas undergo a mitochondrial biogenesis event, corresponding to an incr

188 ssential role of miR-133a in skeletal muscle mitochondrial biogenesis, exercise tolerance, and respon

189 s appear to be regulated, with levels of the mitochondrial biogenesis factor PGC-1alpha falling, and

190 but was reversible by overexpression of the mitochondrial biogenesis factor, mitochondrial transcrip

191 ron reinnervation, myonuclear accretion, and mitochondrial biogenesis for skeletal muscle regeneratio

192 mitochondrial function and repression of the mitochondrial biogenesis gene PGC-1alpha.

193 The observation that DMF stimulates mitochondrial biogenesis, gene expression and function s

194 Interestingly, the mitochondrial biogenesis genes PGC1alpha, PGC1beta, Nrf1

195 duction of transcriptional regulators of the mitochondrial biogenesis, glucose and fatty acid metabol

196 vely required for regulation of B cell size, mitochondrial biogenesis, glycolysis and production of r

197 he role of p53 in BSM cell proliferation and mitochondrial biogenesis has not been investigated thus

198 However, BSM remodeling and mitochondrial biogenesis have not been examined in nonse

199 epair, mitochondrial dynamics, mitophagy and mitochondrial biogenesis, have evolved to preserve mitoc

200 After bleomycin-induced injury, TH promoted mitochondrial biogenesis, improved mitochondrial bioener

201 Here we show that IGF-1 stimulates mitochondrial biogenesis in a range of cell lines.

202 mption in part by inducing thermogenesis and mitochondrial biogenesis in BAT along with enhanced expr

203 Therefore, boosting mitochondrial biogenesis in CAR T cells might improve th

204 These deficiencies of mitochondrial biogenesis in FRDA cells and patient blood

205 Additionally,atRA increased mitochondrial biogenesis in human hepatocytes and in Hep

206 was associated with epigenetic regulation of mitochondrial biogenesis in human placenta in a fetal se

207 ts on genes involved in lipid metabolism and mitochondrial biogenesis in liver and adipose tissue.

208 Our previous studies demonstrated impaired mitochondrial biogenesis in male human placenta of diabe

209 n of genes for oxidative phosphorylation and mitochondrial biogenesis in metabolically active tissues

210 tudies, epigenetic marks possibly related to mitochondrial biogenesis in placentae of women with diab

211 to increase thermogenic gene expression and mitochondrial biogenesis in subcutaneous WAT.

212 Although the role of mitochondrial biogenesis in the adaptive responses of sk

213 Despite no clear signs of increased mitochondrial biogenesis in the liver, CIII assembly and

214 This signaling relay promotes mitochondrial biogenesis in the ovary, and thereby plays

215 scriptional level of miR-133a and stimulated mitochondrial biogenesis in wild-type mice, but failed t

216 ucidate the detrimental effect of hypoxia on mitochondrial-biogenesis in activated CD8(+) T cells, an

217 we show the detrimental effect of hypoxia on mitochondrial-biogenesis in activated mouse CD8(+) T cel

218 Notably, we identified suppression of mitochondrial biogenesis, in particular via peroxisome p

219 Evidence of SIRT1-RELB induction of mitochondrial biogenesis included increases in mitochond

220 Bioinformatic analysis identifies mitochondrial biogenesis including synthesis of glutamat

221 These changes cause decreased mitochondrial biogenesis, increased ROS production, and

222 activator 1alpha (PGC1alpha), which programs mitochondrial biogenesis, induced by chronic Akt signali

223 ced renal expression of master regulators of mitochondrial biogenesis, inhibitors of oxidative stress

224 consistent with the idea that the decreased mitochondrial biogenesis is a consequence of FXN deficie

225 This is the first demonstration that mitochondrial biogenesis is deficient in Multiple Sclero

226 ed BSM mass are complex but involve enhanced mitochondrial biogenesis, leading to increased prolifera

227 0 (mtHsp70) mediates essential functions for mitochondrial biogenesis, like import and folding of pro

228 to mitochondria to present precursors to the mitochondrial biogenesis machinery.

229 In vivo in mice,atRA treatment increased mitochondrial biogenesis markers after an overnight fast

230 c inhibitor, increased the effects ofatRA on mitochondrial biogenesis markers in HepG2 cells and in v

231 quired for the coordinate control of cardiac mitochondrial biogenesis, maturation, and high-capacity

232 , the inhibition of mPTP and the increase in mitochondrial biogenesis may account for the poor pro-ap

233 This study reveals that BSM remodeling and mitochondrial biogenesis may play a critical role in the

234 any acute and chronic degenerative diseases, mitochondrial biogenesis (MB) is a therapeutic target fo

235 GC-1alpha gene expression and its downstream mitochondrial biogenesis (MB) targets under physiologica

236 eceptor (beta2AR) agonist formoterol induces mitochondrial biogenesis (MB), but other beta2AR agonist

237 Mitochondrial biogenesis, membrane potential, and functi

238 factor Kruppel-like factor 4 (KLF4) governs mitochondrial biogenesis, metabolic function, dynamics,

239 We also found increased mitochondrial biogenesis, mitochondrial fusion and synap

240 This altered mitochondrial biogenesis, mitochondrial size, lipid cont

241 tal oxidation-reduction processes, including mitochondrial biogenesis, mitophagy, inflammasome activa

242 There were no compensatory mitochondrial biogenesis (no induction of nuclear respir

243 arkers of mitochondrial injury and recovery (mitochondrial biogenesis) noninvasively in peripheral bl

244 Mfn1, Mfn2 and Opa1 (fusion), CypD (matrix), mitochondrial biogenesis-Nrf1, Nrf2, PGC1alpha and TFAM

245 generation in muscle that was independent of mitochondrial biogenesis or activation of uncoupling pro

246 e improves metabolism partly by upregulating mitochondrial biogenesis or function, via increased leve

247 netic or pharmacologic approaches that block mitochondrial biogenesis or glycolysis resulted in decre

248 urprisingly do not exhibit changes in muscle mitochondrial biogenesis or mitochondrial function and a

249 cytidine monophosphate kinase 1 axis and the mitochondrial biogenesis pathway as targets of the 4EBP1

250 restored expression of the key regulator of mitochondrial biogenesis, peroxisome proliferator-activa

251 of this pathway along with the expression of mitochondrial biogenesis (PGC-1alpha [peroxisome prolife

252 nd ER stress-induced apoptosis, and improved mitochondrial biogenesis, possibly through SERCA2-mediat

253 Thus, DMF induces mitochondrial biogenesis primarily through its action on

254 to chemotherapy (re-)treatment and induced a mitochondrial biogenesis program with increased mitochon

255 a transcriptional coactivator that promotes mitochondrial biogenesis, protects against oxidative str

256 -1alpha K224R mutant significantly increases mitochondrial biogenesis, reactive oxygen species (ROS)

257 We found that 5-HT increased mitochondrial biogenesis, reflected through enhanced mtD

258 Here we show that the mitochondrial biogenesis regulator, PGC1alpha, is a pivo

259 Transcription of the mitochondrial biogenesis regulators peroxisome prolifera

260 oxygen consumption, ATP generation, and key mitochondrial biogenesis regulators were enhanced in NSC

261 s consistent with lower transcription of the mitochondrial biogenesis regulators.

262 APN(-/-) mice showed decreased expression of mitochondrial biogenesis regulatory protein peroxisome p

263 id synthesis and its downregulation improves mitochondrial biogenesis, respiratory capacity and lipid

264 Overall, this leads to reduced mitochondrial biogenesis, resulting in a metabolic switc

265 lation of transcription factors that promote mitochondrial biogenesis, resulting in greater numbers o

266 Exercise training-mediated mitochondrial biogenesis, running endurance, and benefic

267 e 5-HT(2A) receptor and master modulators of mitochondrial biogenesis, SIRT1 and PGC-1alpha.

268 e nucleus coincides with the peak of somatic mitochondrial biogenesis that occurs around a transition

269 d protein response (UPR(mt)), autophagy, and mitochondrial biogenesis, thereby rescuing the mitochond

270 ated, at least in part, by an enhancement of mitochondrial biogenesis through a mechanism involving P

271 These data reveal that necdin promotes mitochondrial biogenesis through stabilization of endoge

272 initiates a rapid and reversible decrease in mitochondrial biogenesis through unclear means.

273 wth, indicating an unknown mechanism linking mitochondrial biogenesis to cell size.

274 ly of transcriptional coactivators regulates mitochondrial biogenesis to control the cellular bioener

275 on of toxic glucose metabolites and inducing mitochondrial biogenesis to restore mitochondrial functi

276 a transcriptional coactivator that promotes mitochondrial biogenesis, to determine whether increased

277 tor gamma coactivator 1-alpha expression and mitochondrial biogenesis, together with a number of BAT

278 th an increased pool of free NADH, increased mitochondrial biogenesis, triggering of the mitochondria

279 , CLL-derived CD8(+) T cells showed impaired mitochondrial biogenesis upon stimulation.

280 a potent PGC-1alpha stabilizer that promotes mitochondrial biogenesis via PGC-1alpha in mammalian neu

281 TFEB activation concomitantly stimulates mitochondrial biogenesis via PGC1alpha induction to rest

282 scle angiogenesis (VEGFA) and (v) energy and mitochondrial biogenesis (via PGC, UCP3, NRF2, AMPK, MAP

283 Induction of mitochondrial biogenesis was dependent on TFAM up-regula

284 dynamics and mitophagy were induced at P1-7, mitochondrial biogenesis was enhanced after P14.

285 scle were swollen with abnormal cristae, and mitochondrial biogenesis was increased.

286 gy markers were examined by western blot and mitochondrial biogenesis was inferred from MitoTimer pro

287 Mitochondrial biogenesis was inhibited as suggested by t

288 links to PGC-1alpha, the master regulator of mitochondrial biogenesis, we searched for compounds that

289 Patients with early activation of mitochondrial biogenesis were ICU-free by 1 week.

290 cose transporters, oxidative metabolism, and mitochondrial biogenesis were induced to similar levels

291 and immunoblotting, whereas genes related to mitochondrial biogenesis were measured via a quantitativ

292 ression of transcription factors involved in mitochondrial biogenesis were quantified by real-time qP

293 1 mRNAs, which encode proteins that regulate mitochondrial biogenesis, were increased following 1alph

294 xpression in Saccharomyces cerevisiae during mitochondrial biogenesis, when OXPHOS complexes are synt

295 ng fibroblasts with the Ras oncogene induced mitochondrial biogenesis, which further elevated OXPHOS.

296 We show that lysosomal dysfunction induced mitochondrial biogenesis, which is mediated by vitamin B

297 pression of Pgc1alpha/beta leads to impaired mitochondrial biogenesis, which, in conjunction with the

298 Therefore, we targeted mitochondrial biogenesis with a mitochondrium-targeted,

299 vides the first evidence of an alteration of mitochondrial biogenesis with early life stress and with

300 d is the first drug demonstrated to increase mitochondrial biogenesis with in vivo human dosing.