ライフサイエンスコーパス: mitochondrial fission

1 le within the nucleus, we observed increased mitochondrial fission.

2 role in mitochondrial dynamics by mediating mitochondrial fission.

3 ial for physiological and pathophysiological mitochondrial fission.

4 cium ([Ca(2+)]cyto), aerobic glycolysis, and mitochondrial fission.

5 -related protein 1 (Drp1), a key mediator of mitochondrial fission.

6 EtOAc on activation of AMPK and promotion of mitochondrial fission.

7 min-related protein 1) is a key regulator of mitochondrial fission.

8 concentrations (e.g., 50 muM) used to target mitochondrial fission.

9 anti-aging effects of midlife Drp1-mediated mitochondrial fission.

10 gene encoding an annotated protein promoting mitochondrial fission.

11 reticulum and a pattern suggesting increased mitochondrial fission.

12 ribosomal disassembly, calcium overload and mitochondrial fission.

13 the AMPK-mediated blockage of Drp1-mediated mitochondrial fission.

14 30c-5p-dependent inhibition of Drp1-mediated mitochondrial fission.

15 smic guanosine triphosphatase that catalyzes mitochondrial fission.

16 regulated S637 phosphorylation, resulting in mitochondrial fission.

17 d that it is a key effector of AMPK-mediated mitochondrial fission.

18 1 is implicated as a passive tether in yeast mitochondrial fission.

19 function could be prevented by inhibition of mitochondrial fission.

20 nvasion, Drp1 mitochondrial localization, or mitochondrial fission.

21 tion-competent Drp1 that can be accessed for mitochondrial fission.

22 ility that MARCH5 is a negative regulator of mitochondrial fission.

23 ochondrial division and fusion by catalyzing mitochondrial fission.

24 of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission.

25 dynamin superfamily, is the main mediator of mitochondrial fission.

26 tin has recently emerged as a participant in mitochondrial fission.

27 e mitochondria participates in Drp1-mediated mitochondrial fission.

28 ce deficient in Mff, a protein important for mitochondrial fission.

29 mitofusin mitochondrial fusion proteins and mitochondrial fission.

30 mitochondria, suggesting that BTICs increase mitochondrial fission.

31 and ionomycin-induced Drp1 accumulation and mitochondrial fission.

32 1), responsible for membrane scission during mitochondrial fission.

33 n-like protein 1, a host protein involved in mitochondrial fission.

34 p1 mitochondrial translocation and increased mitochondrial fission.

35 hepsin E, in promoting emphysema by inducing mitochondrial fission.

36 hances, while Klf5 overexpression suppresses mitochondrial fission.

37 oxidative capacity, consistent with reduced mitochondrial fission.

38 lated protein 1 (DRP1), is a key mediator of mitochondrial fission.

39 omerization over membranes is sufficient for mitochondrial fission.

40 und mitochondria, resulting in inhibition of mitochondrial fission.

41 their organelle network dynamics, including mitochondrial fission.

42 esents an important regulatory mechanism for mitochondrial fission.

43 S capacity, membrane potential, and promoted mitochondrial fission.

44 bitory p-Drp1 (Ser637) content and increased mitochondrial fission.

45 mitochondria is a central step required for mitochondrial fission.

46 ated with dephosphorylation of Drp1 S637 and mitochondrial fission.

47 result in AMPK activation and the consequent mitochondrial fission.

48 reas ARMC10 knockout prevented AMPK-mediated mitochondrial fission.

49 ient than Drp1-WT and Drp1-S637A in inducing mitochondrial fission.

50 optosis, which occurs through the process of mitochondrial fission.

51 e oxygen species (ROS) caused an increase in mitochondrial fission, a response abolished by free radi

52 cells lacking Mdm33 show strongly decreased mitochondrial fission activity indicating that Mdm33 is

53 However, how mitochondrial fission affects progression of DN in vivo

54 ctron microscopy studies suggested increased mitochondrial fission and accumulation of fragmented mit

55 poptosis-related lncRNA (CARL), can suppress mitochondrial fission and apoptosis by targeting miR-539

56 le for the dysfunction of PHB2 and regulates mitochondrial fission and apoptosis by targeting PHB2.

57 roscopy verified that PIM inhibitors promote mitochondrial fission and apoptosis in vivo.

58 ondrial fission process 1 (MTFP1) to control mitochondrial fission and apoptosis.

59 of Dynamin-related protein 1 (DRP1), causing mitochondrial fission and apoptosis.

60 he results show that PHB2 is able to inhibit mitochondrial fission and apoptosis.

61 We found that hypoxia promoted mitochondrial fission and CDDP resistance in ovarian can

62 s implicate that hypoxia-induced ROS trigger mitochondrial fission and CDDP resistance through downre

63 bserved that a super-low dose of LPS induces mitochondrial fission and cell necroptosis in primary mu

64 tivation of Drp1, a molecule responsible for mitochondrial fission and cell necroptosis.

65 s dynamin-related protein 1 (Drp1)-dependent mitochondrial fission and cell sensitivity to stress-ind

66 hosphorylation limited its ability to induce mitochondrial fission and degrade MFN1 and MFN2 but did

67 stological features of DN along with reduced mitochondrial fission and diminished mitochondrial ROS i

68 artment, or MDC, followed by release through mitochondrial fission and elimination by autophagy.

69 5a elicited by Klf5 down-regulation leads to mitochondrial fission and excessive ROS production.

70 on the mitochondria occurs upon induction of mitochondrial fission and F-actin accumulates on the mit

71 Paradigms have held that mitochondrial fission and fragmentation are the result o

72 urpose of this study is to determine whether mitochondrial fission and fragmentation can be an adapti

73 for the evolving conceptual framework, where mitochondrial fission and fragmentation play a role in t

74 Mitochondrial fission and fusion are highly regulated by

75 mortality in mammals when applied in midlife.Mitochondrial fission and fusion are important mechanism

76 Here we show that mitochondrial fission and fusion are spatially coordinat

77 Axonal transport of mitochondria and mitochondrial fission and fusion contribute to this reju

78 l contact untethering events, in addition to mitochondrial fission and fusion events.

79 so cardiac-specific genetic manipulation of mitochondrial fission and fusion factors has proven usef

80 letely understood although an involvement of mitochondrial fission and fusion has been suggested.

81 ting evidence supporting important roles for mitochondrial fission and fusion in cardiac mitochondria

82 of TMEM135 on mitochondria, and imbalance of mitochondrial fission and fusion in mutant Tmem135 as we

83 he importance of SLC25A46 and fine tuning of mitochondrial fission and fusion in pontocerebellar hypo

84 s suggest that the polymorphic regulation of mitochondrial fission and fusion in reactive microglia i

85 these stimuli mechanistically connect to the mitochondrial fission and fusion machinery is poorly und

86 ugh biogenic renewal and mitophagic culling; mitochondrial fission and fusion, 2 components of mitoch

87 e needs of the cell through the processes of mitochondrial fission and fusion.

88 K that participates in dynamic regulation of mitochondrial fission and fusion.

89 also act as regulatory factors that control mitochondrial fission and fusion.

90 role of the actin cytoskeleton in regulating mitochondrial fission and fusion.

91 iogenesis or mitophagy, or the regulation of mitochondrial fission and fusion.

92 ft ventricular fibroblasts) displayed excess mitochondrial fission and had increased expression of PD

93 ing analysis revealed that reduced levels of mitochondrial fission and increased fusion, biogenesis a

94 tion were linked mechanistically to aberrant mitochondrial fission and its regulation by dynamin-rela

95 nstrate that HSCs achieve this by regulating mitochondrial fission and lysosomal activity, suppressin

96 While both mitochondrial fission and mitochondrial fusion mutants s

97 Mitochondrial fission and mitophagy are quality control

98 Thus, FUNDC1 integrates mitochondrial fission and mitophagy at the interface of

99 phospho-mimic mutant (S637D-Drp1), restored mitochondrial fission and mitophagy in response to creno

100 Strategies that limit mitochondrial fission and mitophagy in the physiologic r

101 However, unchecked mitochondrial fission and mitophagy may compromise the v

102 These results suggest that HCV-induced mitochondrial fission and mitophagy serve to attenuate a

103 cardiomyocyte death is mediated by unchecked mitochondrial fission and mitophagy.

104 membrane potential (DeltaPsim) and promoted mitochondrial fission and mitosis.

105 estruction, cyclin C promotes stress-induced mitochondrial fission and programmed cell death, indicat

106 le phosphorylation site in Drp1 can regulate mitochondrial fission and progression of DN in vivo, and

107 we show that Shh signaling activity reduces mitochondrial fission and promotes mitochondrial elongat

108 cycling of mitochondrial DLP1 complex during mitochondrial fission and provide a novel therapeutic ta

109 naling and dampened response to PDGF-induced mitochondrial fission and reactive oxygen species levels

110 Here, we show that glucose load results in mitochondrial fission and reduced reactive oxygen specie

111 bitor of Drp1, Mdivi1, significantly blunted mitochondrial fission and rescued key pathologic feature

112 Inhibition of PIM kinases caused excessive mitochondrial fission and significant upregulation of mi

113 function of neurotrophins; the regulation of mitochondrial fission and steady state mitochondrial len

114 Here, we describe a new pathway mediating mitochondrial fission and subsequent mitophagy under hyp

115 on of MiD49 is a novel mechanism controlling mitochondrial fission and, consequently, the cellular re

116 r reduced organelle Ca(2+) exchange, induced mitochondrial fission, and altered GSIS.

117 first to identify links between cathepsin E, mitochondrial fission, and caspase activation/apoptosis

118 osphorylation is required for Ras-associated mitochondrial fission, and its inhibition is sufficient

119 he Drp1 receptor Mff is a major regulator of mitochondrial fission, and its overexpression results in

120 1 phosphorylation at serine 616, and thus of mitochondrial fission, and suggest that there are intera

121 cts on ER-to-mitochondrial calcium transfer, mitochondrial fission, and vesicle transport.

122 We identified a previously unknown mitochondrial fission arrest phenotype that results in e

123 AND We demonstrate a novel role for cardiac mitochondrial fission as a normal adaptation to increase

124 tion completely, and we identified decreased mitochondrial fission as the potential driving force for

125 that calcium influx and Drp1-mediated, rapid mitochondrial fission at the injury site help polarize t

126 s of Tau in maintaining dendritic spines and mitochondrial fission biology, two subcellular niches af

127 Furthermore, not only mitochondrial fission but also fusion is regulated throu

128 t mouse cardiac myocytes not only interrupts mitochondrial fission, but also markedly upregulates Par

129 nges in mitochondrial redox status increased mitochondrial fission by increased ubiquitination of AKA

130 feature of necrotic death, and inhibition of mitochondrial fission by Mdivi also resulted in reduced

131 a to the nerve terminal, and a disruption in mitochondrial fission can contribute to the preferential

132 Mitochondrial fission catalyzed by dynamin-related prote

133 evity requires UNC-64/syntaxin, and promotes mitochondrial fission cell nonautonomously.

134 r studies establish a link between defective mitochondrial fission, cellular senescence and age-depen

135 his pattern is disrupted by mutations in the mitochondrial fission component dynamin DRP-1.

136 ngs indicate that interventions that promote mitochondrial fission could delay the onset of pathology

137 Pex16 deficiency blocked cold-induced mitochondrial fission, decreased mitochondrial copy numb

138 Inhibition of mitochondrial fission decreases ROS production and VSMC

139 Furthermore the mitochondrial fission defect in patient fibroblasts was

140 vation of methionine synthase suppressed the mitochondrial fission defect of a dynamin mutation.

141 low vitamin B12 also strongly suppressed the mitochondrial fission defect.

142 ically disorganized mitochondria caused by a mitochondrial fission-defective dynamin mutation is stro

143 Inhibition of mitochondrial fission disrupted both the age-dependent s

144 ood because mutants specifically impaired in mitochondrial fission do not show obvious defects in veg

145 We found that disrupting mitochondrial fission (DRP1/drp-1) or fusion (OPA1/eat-3

146 anterograde motor Kif5B, and an effector of mitochondrial fission, Drp1.

147 We observed mitochondrial fission during osmotic stress, but blockin

148 tor-1 (mdivi-1), a putative inhibitor of the mitochondrial fission Dynamin-Related Protein-1 (Drp1).

149 The essential mediator of mitochondrial fission, dynamin-related protein 1 (DRP1),

150 ar mechanism for the involvement of VPS35 in mitochondrial fission, dysregulation of which is probabl

151 elated protein 1 (Drp1) levels and excessive mitochondrial fission, enhance mitochondrial fusion acti

152 Suppression of mitochondrial fission enhanced the CDDP sensitivity of h

153 eviously acts as a positive regulator of the mitochondrial fission enzyme dynamin-related protein 1 (

154 During ionomycin-induced mitochondrial fission, F-actin clouds colocalize with mi

155 concomitant binding of phospho-Drp1S600 with mitochondrial fission factor (Mff) and actin-related pro

156 We found that the receptors mitochondrial fission factor (Mff) and mitochondrial elo

157 nstrate that the translational inhibition of mitochondrial fission factor (MFF) regulates cellular ho

158 A screen for substrates of AMPK identified mitochondrial fission factor (MFF), a mitochondrial oute

159 Mitochondrial fission factor (Mff), a tail-anchored memb

160 One such Drp1 partner protein, mitochondrial fission factor (Mff), is essential for mit

161 binding to the MOM resident adaptor protein mitochondrial fission factor (Mff).

162 have identified the protein complex between mitochondrial fission factor (MFF1 and MFF2) and voltage

163 ochondrial fragmentation is dependent on the mitochondrial fission factor DRP-1 (dynamin-related prot

164 Finally, deleting the mitochondrial fission factor DRP-1 renders the animal re

165 e II (CaMKII) and the phosphorylation of the mitochondrial fission factor Drp1 at Ser(616) The lack o

166 ndrial dynamics through interaction with the mitochondrial fission factor Drp1 in fed cells and in au

167 Genetic inhibition of the activity of the mitochondrial fission factor dynamin-related protein 1 (

168 l units and was initially considered a major mitochondrial fission factor, with this major role being

169 ein 1 (Drp1) and its mitochondrial receptor, mitochondrial fission factor.

170 oteins, large GTPases that serve as the main mitochondrial fission factors.

171 the canonical Wnt-3a ligand had no effect on mitochondrial fission-fusion events, suggesting that thi

172 The process of mitochondrial fission-fusion has been implicated in dive

173 e that Wnt-5a/Ca(2+) signaling regulates the mitochondrial fission-fusion process in hippocampal neur

174 In searching for mitochondrial fission-fusion regulating proteins for imp

175 rial traffic, and a significant shift in the mitochondrial fission-fusion steady state.

176 hyl-4-phenylpyridinium (MPP(+)) dysregulates mitochondrial fission-fusion, mitophagy, and mitochondri

177 and decoupling of mitochondria with the SSC, mitochondrial fission/fusion imbalance, a remarkable red

178 nd 3D ultrastructural analyses, we show that mitochondrial fission/fusion in reactive microglia is di

179 The mitochondrial fission/fusion ratio and proliferation in

180 d previously that a missense mutation in the mitochondrial fission gene Dynamin-related protein 1 (Dr

181 damage and death, our findings identify that mitochondrial fission generates localized signaling requ

182 Increased expressions of mitochondrial fission genes, decreased expression of fus

183 l cells that encode 0, 1 or 2 alleles of the mitochondrial fission GTPase Drp1 and demonstrate that t

184 16) describe a novel interaction between the mitochondrial fission GTPase Drp1 and phosphatidic acid

185 Multiple isoforms of the mitochondrial fission GTPase dynamin-related protein 1 (

186 e oligomerization dynamics of the GFP-tagged mitochondrial fission GTPase dynamin-related protein 1 (

187 Specifically, we show that inhibition of the mitochondrial fission GTPase dynamin-related protein-1 (

188 chondrial protein ATAD3A as an interactor of mitochondrial fission GTPase, Drp1, in HD.

189 Mitochondrial fission has been linked to the pathogenesi

190 Drp1, a key regulator of mitochondrial fission, has been shown to be activated an

191 8's previously unexplored role in regulating mitochondrial fission, implicates MTP18 as a downstream

192 of atherosclerosis by reducing Drp1-mediated mitochondrial fission in an AMPK-dependent manner.

193 g one of the three main proteins involved in mitochondrial fission in Arabidopsis (Arabidopsis thalia

194 They show that chronic stress promotes mitochondrial fission in CD4(+) T cells, causing increas

195 otential therapeutic treatment of disrupting mitochondrial fission in cocaine addiction.

196 es-accelerated atherosclerosis by inhibiting mitochondrial fission in endothelial cells.

197 Mechanistically, we showed that mitochondrial fission in high glucose conditions occurs

198 ial fusion and synaptic activity and reduced mitochondrial fission in ligand 1-treated mutant APP cel

199 ne a signaling axis linking PIM1 to Drp1 and mitochondrial fission in lung cancer.

200 ed' mitochondria, and show that induction of mitochondrial fission in midlife, but not in early life,

201 tes from within mitochondria and the role of mitochondrial fission in mitophagy.

202 Thus, mitochondrial fission in response to AC uptake is a crit

203 r dynamin-related protein 1 (Drp1)-dependent mitochondrial fission in response to oxidative stress.

204 GTP-hydrolyzing mechanoenzyme that catalyzes mitochondrial fission in the cell.

205 at the effect of Drp1S600 phosphorylation on mitochondrial fission in the diabetic milieu was stimulu

206 rmally clustered tubular ER induces enhanced mitochondrial fission in the early stages of DN formatio

207 Defective mitochondrial fission in the elm1 and drp3b mutants caus

208 ed number of mitochondria because of reduced mitochondrial fission in the former and elevated fission

209 We demonstrate a role for altered mitochondrial fission in the NAc, during early cocaine a

210 of Drp1 Serine 600 (S600) phosphorylation on mitochondrial fission in vivo, and assessed the function

211 Promoting Drp1-mediated mitochondrial fission, in midlife, facilitates mitophagy

212 Drp1-a Dynamin-related protein that promotes mitochondrial fission-in midlife, prolongs Drosophila li

213 o study one aspect of mitochondrial dynamics-mitochondrial fission-in mouse DA neurons, we deleted th

214 Mitochondrial fission-induced mitochondrial function ele

215 ochondrial division inhibitor 1 (mdivi-1), a mitochondrial fission inhibitor.

216 so correlates with sensitivity to Mdivi-1, a mitochondrial fission inhibitor.

217 Mitochondrial fission involves the preconstriction of an

218 Mitochondrial fission is a crucial cellular process medi

219 Here, we show that mitochondrial fission is also important for regulating t

220 Although mitochondrial fission is considered to be an indicator o

221 When mitochondrial fission is disabled, AC-induced increase i

222 Mitochondrial fission is essential for the degradation o

223 tein Drp1, we demonstrate in this study that mitochondrial fission is necessary for glucose-stimulate

224 his study we evaluated whether inhibition of mitochondrial fission is neuroprotective against alpha-s

225 Our studies suggest that mitochondrial fission is required for proper mitochondri

226 Here, we show that mitochondrial fission is triggered by mechanical forces.

227 Dynamin-related protein 1, a regulator of mitochondrial fission, is an important determinant of re

228 gradation of Dnm1, the main factor mediating mitochondrial fission, is impaired in the absence of BLM

229 (Dlp1; official name DNM1L), which promotes mitochondrial fission, is lower in astrocytes from the b

230 RIPK3 promotes mitochondrial fission leading to elevated oxidative stre

231 surfaces - results in the recruitment of the mitochondrial fission machinery, and subsequent division

232 has been shown to recruit to peroxisomes the mitochondrial fission machinery, thus enabling prolifera

233 rmation was highly dependent on a functional mitochondrial fission machinery.

234 pporting a revised model for assembly of the mitochondrial fission machinery.

235 Abeta catabolism as well as hyperactivating mitochondrial fission machinery.

236 induced the autophagic marker Parkin and the mitochondrial fission marker Dynamin-related protein 1 (

237 Pharmacological targeting of mitochondrial fission may be a promising therapy for car

238 Collectively, these data suggest mitochondrial fission may be a target for treating MAPK-

239 Suppression of mitochondrial fission may be a therapeutic approach for

240 These results suggest that Drp1-dependent mitochondrial fission may regulate susceptibility to hea

241 min GTPase Drp1 plays a critical role during mitochondrial fission, mechanisms controlling its recrui

242 Mitochondrial fission mediated by the GTPase dynamin-rel

243 We show here that E50K expression induces mitochondrial fission-mediated mitochondrial degradation

244 ing this phenotype, through knockdown of the mitochondrial fission-mediating GTPase Drp1, inhibits tu

245 ase of dynamin-related protein-1 (Drp1), the mitochondrial fission mediator, in nucleus accumbens (NA

246 hus, in addition to their canonical roles in mitochondrial fission, Mff and Drp1 also act as regulato

247 ochondrial-division inhibitor 1 (Mdivi-1) on mitochondrial fission, mitochondrial biogenesis, electro

248 ncluding genes encoding proteins involved in mitochondrial fission, morphology, and lipid homeostasis

249 Mitochondrial fission occurs frequently in plant cells,

250 Drp1 then further constricts membranes until mitochondrial fission occurs.

251 protein 1 (Drp1), an essential component of mitochondrial fission, on the pathogenesis and progressi

252 ision Inhibitor 1 (mdivi-1), an inhibitor of mitochondrial fission, on the structure and function of

253 ied, the precise cellular cues that initiate mitochondrial fission or fusion remain largely unknown.

254 x is resolved by the findings that excessive mitochondrial fission or inhibition of fusion alleviates

255 Aberrant mitochondrial fission plays a pivotal role in the pathog

256 otein MiD49 fail to undergo injury-triggered mitochondrial fission, preventing polarized mitochondria

257 complex 1 (mTORC1) stimulates translation of mitochondrial fission process 1 (MTFP1) to control mitoc

258 ondrial network through the targeting of the mitochondrial fission process 1 protein MTP18, leading t

259 th within the visual system, we uncover that mitochondrial fission process 1,18 kDa (MTP18/MTFP1), a

260 m homeostasis were measured in intact cells; mitochondrial fission promoted lower basal cellular calc

261 xamples, including altMiD51, a 70 amino acid mitochondrial fission-promoting protein encoded in MiD51

262 ed absence of the STAT2 protein and that the mitochondrial fission protein DRP1 (encoded by DNM1L) is

263 the mitochondrial apoptosis pathway and the mitochondrial fission protein Drp1 contribute to mitotic

264 nd immunostaining analysis revealed that the mitochondrial fission protein Drp1 interacted with Abeta

265 protein MFN2 nor inhibition/ablation of the mitochondrial fission protein DRP1 was able to do so, im

266 By acute pharmacological inhibition of mitochondrial fission protein Drp1, we demonstrate in th

267 on, at least in part, via suppression of the mitochondrial fission protein dynamin-like GTPase Drp1.

268 ted in increased E3 ubiquitin ligase parkin, mitochondrial fission protein dynamin-related protein 1,

269 Embryos mutant for the mitochondrial fission protein, Drp1 (dynamin-related pro

270 lial reactions, caused the activation of the mitochondrial fission protein, dynamin-related protein 1

271 his effect is mediated by phosphorylation of mitochondrial fission protein, dynamin-related protein 1

272 ion with an unchanged OMM (visualized by Eos-mitochondrial fission protein-1).

273 We also found that the mitochondrial fission proteins Drp1 and Mff negatively r

274 Mitochondrial fission, regulated by dynamin-related prot

275 amin-related protein 1 (DRP1), a mediator of mitochondrial fission, regulates mitochondrial function;

276 R-30c-5p led to the up-regulation of Drp1, a mitochondrial fission regulator and a target gene of p53

277 er stress because of loss of activity of the mitochondrial fission regulator Drp1 onto mitochondria.

278 hondrial fragmentation in GCDC by inhibiting mitochondrial fission significantly decreased not only R

279 n the liver, we demonstrated that decreasing mitochondrial fission substantially diminished ROS level

280 Although inhibiting Drp1-mediated mitochondrial fission suppresses the segregation of mito

281 emonstrate a mechanism for the regulation of mitochondrial fission that is dictated by the interactio

282 In both cell lines, the inhibition of mitochondrial fission that leads to a mitochondrial stru

283 DRP1 is thereby recruited to the MAM, and mitochondrial fission then occurs.

284 Mechanistically, PGAM5 is required for mitochondrial fission through dephosphorylating DRP1.

285 rown adipocytes was reduced by inhibition of mitochondrial fission through transient Drp1 DN overexpr

286 Here, we demonstrate that mitochondrial fission, together with the lack of mtDNA r

287 NIK promotes mitochondrial fission, velocity, and directional migrati

288 es mitochondrial biogenesis and then affects mitochondrial fission via chromatin pathways.

289 Overall, succinate promotes DRP1-mediated mitochondrial fission via GPR91, consequently stimulatin

290 tein kinase (AMPK) activation by 991 promote mitochondrial fission via phosphorylation of MFF and ind

291 K activation promotes mitophagy by enhancing mitochondrial fission (via MFF phosphorylation) and auto

292 Indeed, mitochondrial fission was associated with ER stress.

293 Mitochondrial fission was associated with increased lact

294 fusion or dynamin-related protein 1-mediated mitochondrial fission was conditionally interrupted in c

295 Following resuscitation from cardiac arrest, mitochondrial fission was evidenced by dynamin-related p

296 tant, as this domain is sufficient to induce mitochondrial fission when expressed in mouse embryonic

297 C10 overexpression was sufficient to promote mitochondrial fission, whereas ARMC10 knockout prevented

298 n.Key to maintaining mitochondrial health is mitochondrial fission, which facilitates the dynamic exc

299 es dynamin-related protein 1 (Drp1)-mediated mitochondrial fission, which is triggered by AC uptake.

300 BAX has consistently been associated with mitochondrial fission, yet how BAX participates in the p