ライフサイエンスコーパス: mitochondrial outer membrane

1 utes to this process by forming pores in the mitochondrial outer membrane.

2 into a toxic oligomer that permeabilizes the mitochondrial outer membrane.

3 translocase complex and forms a pore in the mitochondrial outer membrane.

4 actor of the translocase supercomplex of the mitochondrial outer membrane.

5 ing to Bax-dependent permeabilization of the mitochondrial outer membrane.

6 ess is localized on the outer surface of the mitochondrial outer membrane.

7 forming homo-oligomers that permeabilize the mitochondrial outer membrane.

8 their self-association to form pores in the mitochondrial outer membrane.

9 CBS localized to the cytosol, as well as the mitochondrial outer membrane.

10 1 protein located in discrete patches in the mitochondrial outer membrane.

11 he voltage-dependent anion channel (VDAC) of mitochondrial outer membrane.

12 omplex, which physically connects the ER and mitochondrial outer membrane.

13 eta-barrel proteins and insert them into the mitochondrial outer membrane.

14 K and BAX form large oligomeric pores in the mitochondrial outer membrane.

15 pro-apoptotic activity by permeabilizing the mitochondrial outer membrane.

16 psis (Arabidopsis thaliana) localized in the mitochondrial outer membrane.

17 s expressed in the heart and can bind to the mitochondrial outer membrane.

18 of arrested and mislocalized proteins at the mitochondrial outer membrane.

19 either the endoplasmic reticulum (ER) or the mitochondrial outer membrane.

20 h assembles its replication complexes on the mitochondrial outer membrane.

21 ins activate BAK and BAX to permeabilize the mitochondrial outer membrane.

22 and translocates into and permeabilizes the mitochondrial outer membrane.

23 transfer of metabolites and ions across the mitochondrial outer membrane.

24 m, Sox10 is peripherally associated with the mitochondrial outer membrane.

25 t or assembly of beta-barrel proteins in the mitochondrial outer membrane.

26 on induction and localization of MAVS to the mitochondrial outer membrane.

27 RMCX3 is an integral membrane protein of the mitochondrial outer membrane.

28 argets a critical regulatory molecule at the mitochondrial outer membrane.

29 aling in maintenance of the integrity of the mitochondrial outer membrane.

30 (DeltaPsi(m)) but does not permeabilize the mitochondrial outer membrane.

31 Puf3p localizes to the cytosolic face of the mitochondrial outer membrane.

32 and reduction of metabolite flow across the mitochondrial outer membrane.

33 r primary pro- or antiapoptotic roles at the mitochondrial outer membrane.

34 Bcl-xL in regulating apoptotic events in the mitochondrial outer membrane.

35 lic fractions from rat brain, as well as the mitochondrial outer membrane.

36 family proteins regulate the permeability of mitochondrial outer membrane.

37 insertion of its N-terminal domain into the mitochondrial outer membrane.

38 localized tail-anchored ER proteins from the mitochondrial outer membrane.

39 complex, a protein-conducting channel in the mitochondrial outer membrane.

40 tes Larp to inhibit protein synthesis on the mitochondrial outer membrane.

41 endent anion channel (VDAC) oligomers in the mitochondrial outer membrane.

42 mitochondria, but it is associated with the mitochondrial outer membrane.

43 R associations occurred on extensions of the mitochondrial outer membrane.

44 ammalian ortholog, Drp1, was undetectable in mitochondrial outer membranes.

45 s consistent with results obtained in native mitochondrial outer membranes.

46 ramide to form protein-permeable channels in mitochondrial outer membranes.

47 ransmembrane GTPase Fzo1p controls fusion of mitochondrial outer membranes.

48 ers that control the permeabilization of the mitochondrial outer membrane, a crucial step in the modu

49 ltage-dependent anion channels (VDAC) in the mitochondrial outer membrane after ethanol exposure lead

50 e proapoptotic protein Bax permeabilizes the mitochondrial outer membrane, allowing the release of pr

51 on, is routinely found to be associated with mitochondrial outer membranes, although the structure an

52 serine-threonine protein kinase PINK1 on the mitochondrial outer membrane and activates Parkin.

53 l (VDAC) is the most abundant protein in the mitochondrial outer membrane and an archetypical beta-ba

54 family proteins regulate permeability of the mitochondrial outer membrane and apoptosis.

55 raction of nitrated Hsp90 was located on the mitochondrial outer membrane and down-regulated mitochon

56 membrane domain, targeted the protein to the mitochondrial outer membrane and exerted antiapoptotic f

57 hat MceA is specifically integrated into the mitochondrial outer membrane and forms a complex of appr

58 age dependent anion channel 1 (VDAC1) on the mitochondrial outer membrane and inhibited its opening.

59 member (known as NLR) that localizes to the mitochondrial outer membrane and interacts with MAVS.

60 ulin interacts with integral proteins of the mitochondrial outer membrane and is important for the st

61 domain of Tom22 on the cytosolic side of the mitochondrial outer membrane and links TOM and SAM compl

62 we report that betaIIPKC accumulates on the mitochondrial outer membrane and phosphorylates mitofusi

63 We found that NSm integrates into the mitochondrial outer membrane and that the protein's N te

64 They are embedded in the mitochondrial outer membrane and thought to fuse adjacen

65 ted X (Bax) protein, permeabilization of the mitochondrial outer membrane, and cell death.

66 passage of a variety of molecules across the mitochondrial outer membrane, and is central to mitochon

67 ainly distributed in the cytosol, not in the mitochondrial outer membrane as previously reported, sug

68 processed HtrA2 prevents the accumulation of mitochondrial-outer-membrane-associated activated Bax, a

69 Whether formed in liposomes or in mitochondrial outer membranes, Bax-induced pores exhibit

70 arly in mitochondria-mediated apoptosis, the mitochondrial outer membrane becomes permeable to protei

71 orting and assembly machinery/topogenesis of mitochondrial outer membrane beta-barrel proteins (SAM/T

72 membranes that have no consequences for the mitochondrial outer membrane but inhibit Bax membrane in

73 Mff and Fis1 are both tail anchored in the mitochondrial outer membrane, but other parts of these p

74 tosis by inhibiting BAX translocation to the mitochondrial outer membrane, but the molecular mechanis

75 to large assemblies of VDAC are observed in mitochondrial outer membranes, but they do not predomina

76 newly identified pathway is regulated at the mitochondrial outer membrane by a complex between the pr

77 poptosis by maintaining the integrity of the mitochondrial outer membrane by adopting both soluble an

78 oltage-dependent anion channel (VDAC) of the mitochondrial outer membrane by dimeric tubulin is being

79 Dislocation of polypeptides from the mitochondrial outer membrane by the p97/Cdc48-Ufd1-Npl4

80 nt levels, ceramides form stable channels in mitochondrial outer membranes capable of passing the lar

81 All mitochondrial outer membrane channels known to date are

82 endent but independent of protease-sensitive mitochondrial outer membrane components or the host mito

83 and other respiratory substrates through the mitochondrial outer membrane, constituting a crucial poi

84 We found that mitochondrial outer membranes contained very little card

85 We conclude that the mitochondrial outer membrane contains a considerably lar

86 The mitochondrial outer membrane contains proteinaceous mach

87 eractions among BCL-2 family proteins at the mitochondrial outer membrane control the release of thes

88 interaction of Bcl-2 family proteins at the mitochondrial outer membrane controls membrane permeabil

89 rthermore, the Mcl-1 expression level at the mitochondrial outer membrane determines the release effi

90 haracterized by Bax translocalization to the mitochondrial outer membrane, disruption of the mitochon

91 strictions suitable for Drp1 assembly on the mitochondrial outer membrane; Drp1 then further constric

92 lieved to form large oligomeric pores in the mitochondrial outer membrane during apoptosis.

93 and Bak mediate the permeabilization of the mitochondrial outer membrane during apoptosis.

94 ges to homooligomerize then permeabilize the mitochondrial outer membrane during apoptosis.

95 nd MceA is a complex-forming effector at the mitochondrial outer membrane during Coxiella infection.

96 MceA forms a homo-oligomeric species at the mitochondrial outer membrane during infection.

97 -apoptotic BCL-2 proteins oligomerize at the mitochondrial outer membrane during MOMP, inducing pore

98 ssaying in which GRASP65 was targeted to the mitochondrial outer membrane either directly or via bind

99 n the endoplasmic reticulum membrane and the mitochondrial outer membrane facilitate efficient transf

100 ivation of a ubiquitin ligase complex at the mitochondrial outer membrane for temporally and spatiall

101 endent anion channel 1 (VDAC1), found in the mitochondrial outer membrane, forms the main interface b

102 family of small pore-forming proteins of the mitochondrial outer membrane found in all eukaryotes.

103 in 2, which is an essential component of the mitochondrial outer membrane fusion apparatus, and the u

104 e structural insights into the mechanisms of mitochondrial outer membrane fusion by investigating the

105 Mitofusin (Mfn) 1 and 2 mediate mitochondrial outer membrane fusion, whereas Mfn2 but no

106 2 are nonredundant and are both required for mitochondrial outer membrane fusion.

107 ns) are dynamin-related GTPases that mediate mitochondrial outer-membrane fusion, a process that is r

108 We show that the mitochondrial outer membrane guanosine triphosphatase mi

109 A adopts a polytopic conformation within the mitochondrial outer membrane, having both the N- and C-t

110 ctive protein [HTATIP], Vimentin, fission 1 (mitochondrial outer membrane) homolog [FIS1], and protei

111 eins form nanometer-sized clusters along the mitochondrial outer membrane in association with the Mit

112 peptides potently trigger disruption of the mitochondrial outer membrane in cells dependent on Bfl-1

113 timulator, La-related protein (Larp), to the mitochondrial outer membrane in ovaries.

114 ate, it is unclear how Drp1 assembles on the mitochondrial outer membrane in response to different li

115 change localization from the cytosol to the mitochondrial outer membrane in this regulation.

116 odeling protein that mediates fusion between mitochondrial outer membranes in animals and fungi.

117 nion channel (VDAC), isolated from rat liver mitochondrial outer membranes, including the transmembra

118 Targeting Larp to the mitochondrial outer membrane independently of MDI restor

119 eins that regulates apoptosis by controlling mitochondrial outer membrane integrity.

120 Permeabilization of the mitochondrial outer membrane is a key step in the intrin

121 In mammals, fusion of the mitochondrial outer membrane is controlled by two DRPs,

122 The mitochondrial outer membrane is essential for communicat

123 Association of tBid on the mitochondrial outer membrane is key to its biological fu

124 pro-apoptotic Bax protein permeabilizes the mitochondrial outer membrane is not fully understood.

125 During apoptosis, the mitochondrial outer membrane is permeabilized, leading t

126 Fusion of mitochondrial outer membranes is crucial for proper orga

127 HP1, or PTPN6) from Sab in the inside of the mitochondrial outer membrane, leading to its activation

128 ivation of large-conductance channels in the mitochondrial outer membrane, mitochondrial release of c

129 ix alpha9 of Bax protein can dimerize in the mitochondrial outer membrane (MOM) and lead to apoptotic

130 mHTT is located on the cytosolic side of the mitochondrial outer membrane (MOM) but does not cross it

131 hway to apoptosis is permeabilization of the mitochondrial outer membrane (MOM) by oligomers of the B

132 se results demonstrate how lipid cues at the mitochondrial outer membrane (MOM) can alter Drp1 struct

133 nitine palmitoyltransferase 1a) in the liver mitochondrial outer membrane (MOM) catalyzes the primary

134 PINK1 promotes PARKIN recruitment to the mitochondrial outer membrane (MOM) for ubiquitylation of

135 ell lymphoma-2 (Bcl-2) protein family in the mitochondrial outer membrane (MOM) induce structural cha

136 Regulation of mitochondrial outer membrane (MOM) permeability has dual

137 blish temperature-sensitive (ts-) peripheral mitochondrial outer membrane (MOM) proteins as novel mod

138 Strikingly, the incorporation of isolated mitochondrial outer membrane (MOM) proteins into liposom

139 activity of Bax, but it is unclear how other mitochondrial outer membrane (MOM) proteins might facili

140 d insertion machinery has been uncovered for mitochondrial outer membrane (MOM) TA proteins.

141 Whereas PARKIN is recruited to the mitochondrial outer membrane (MOM) upon depolarization v

142 ernal surface of the mitochondria, i.e., the mitochondrial outer membrane (MOM), and modulate its per

143 d Bax changes conformation, inserts into the mitochondrial outer membrane (MOM), oligomerizes, and in

144 haemia by enhancing Drp1 partitioning to the mitochondrial outer membrane (MOM), which causes cytochr

145 In this review we examine recent findings on mitochondrial outer membrane (MOM)-associated mRNA trans

146 after the complete recruitment of BAX to the mitochondrial outer membrane (MOM).

147 survival by protecting the integrity of the mitochondrial outer membrane (MOM).

148 ) to visualize Bax-induced pores in purified mitochondrial outer membranes (MOMs).

149 n of tBid via a conformational change at the mitochondrial outer membrane, Mtch2 accelerates tBid-med

150 form that is similar to the one found in the mitochondrial outer membrane of drug-treated cells.

151 Monoamine oxidase B, present in the mitochondrial outer membrane of glial cells, catalyzes t

152 ologue, disassemble ceramide channels in the mitochondrial outer membranes of isolated mitochondria f

153 The mitochondrial outer membrane (OM) contains single and mu

154 drion-associated membrane compartment to the mitochondrial outer membrane (OMM), where they inactivat

155 nery and dynamin-related protein 1 (Drp1) on mitochondrial outer membrane (OMM).

156 ion of apoptotic cell death involved loss of mitochondrial outer membrane permeability and activation

157 lin C, but not Cdk8, is required for loss of mitochondrial outer membrane permeability and apoptosis

158 f the mitochondrial lipids in control of the mitochondrial outer membrane permeability and hence mito

159 uter mitochondrial membrane (OMM) to promote mitochondrial outer membrane permeabilization (MOMP) and

160 racting-domain death agonist, BID) to induce mitochondrial outer membrane permeabilization (MOMP) and

161 ng the long and variable delay that precedes mitochondrial outer membrane permeabilization (MOMP) and

162 Both mitochondrial outer membrane permeabilization (MOMP) and

163 can be used for light-mediated initiation of mitochondrial outer membrane permeabilization (MOMP) and

164 Pro-apoptotic Bax induces mitochondrial outer membrane permeabilization (MOMP) by

165 BCL-2 family proteins control mitochondrial outer membrane permeabilization (MOMP) by

166 inhibiting Bax oligomerization required for mitochondrial outer membrane permeabilization (MOMP) dur

167 Mitochondrial outer membrane permeabilization (MOMP) has

168 -dependent apoptosis execution subsequent to mitochondrial outer membrane permeabilization (MOMP) in

169 Most apoptotic stimuli require mitochondrial outer membrane permeabilization (MOMP) in

170 Mitochondrial outer membrane permeabilization (MOMP) is

171 Bax/Bak-mediated mitochondrial outer membrane permeabilization (MOMP) is

172 Mitochondrial outer membrane permeabilization (MOMP) is

173 During apoptosis, mitochondrial outer membrane permeabilization (MOMP) is

174 Mitochondrial outer membrane permeabilization (MOMP) is

175 Mitochondrial outer membrane permeabilization (MOMP) is

176 els of caspase activity triggered by limited mitochondrial outer membrane permeabilization (MOMP) pro

177 rface of apoptosis initiation and execution, mitochondrial outer membrane permeabilization (MOMP) rep

178 Upon induction of mitochondrial apoptosis, mitochondrial outer membrane permeabilization (MOMP) usu

179 ntrinsic apoptotic pathway and the resultant mitochondrial outer membrane permeabilization (MOMP) via

180 Bax induces mitochondrial outer membrane permeabilization (MOMP), a

181 Mitochondrial outer membrane permeabilization (MOMP), a

182 ell lymphoma (BCL-2) protein family regulate mitochondrial outer membrane permeabilization (MOMP), a

183 The mechanism of Bax/Bak-dependent mitochondrial outer membrane permeabilization (MOMP), a

184 The defining event in apoptosis is mitochondrial outer membrane permeabilization (MOMP), al

185 oapoptotic members of the Bcl-2 family cause mitochondrial outer membrane permeabilization (MOMP), al

186 apoptosis, the BCL-2 protein family controls mitochondrial outer membrane permeabilization (MOMP), bu

187 (PIs) avert apoptosis in part by preventing mitochondrial outer membrane permeabilization (MOMP), bu

188 apoptosis involving regulation of Bax/Bcl-2, mitochondrial outer membrane permeabilization (MOMP), cy

189 fficient apoptosis requires Bax/Bak-mediated mitochondrial outer membrane permeabilization (MOMP), wh

190 Apoptosis induces cell death through mitochondrial outer membrane permeabilization (MOMP), wh

191 ondrial pathway of apoptosis is initiated by mitochondrial outer membrane permeabilization (MOMP).

192 es apoptosis by activating Bax and eliciting mitochondrial outer membrane permeabilization (MOMP).

193 ing the apoptotic deficiency at the level of mitochondrial outer membrane permeabilization (MOMP).

194 a critical step in apoptosis referred to as mitochondrial outer membrane permeabilization (MOMP).

195 d BAX are required for apoptosis and trigger mitochondrial outer membrane permeabilization (MOMP).

196 proteins control a decisive apoptotic event: mitochondrial outer membrane permeabilization (MOMP).

197 pressing reporters of caspase activation and mitochondrial outer membrane permeabilization after expo

198 by producing G-CSF and GM-CSF, delaying the mitochondrial outer membrane permeabilization and caspas

199 activates an apical protease that stimulates mitochondrial outer membrane permeabilization and proces

200 Mitochondrial outer membrane permeabilization and the re

201 Most importantly, mitochondrial outer membrane permeabilization becomes a

202 NG knockdown, mitochondrial DNA depletion or mitochondrial outer membrane permeabilization blockage v

203 In the absence of active caspases, mitochondrial outer membrane permeabilization by Bax and

204 ttenuated H37Ra or the virulent H37Rv causes mitochondrial outer membrane permeabilization characteri

205 ily that plays a pivotal role in controlling mitochondrial outer membrane permeabilization during apo

206 vents mitochondria division and Bax-mediated mitochondrial outer membrane permeabilization during apo

207 ntial in mammals, in flies the importance of mitochondrial outer membrane permeabilization for apopto

208 most intrinsic apoptotic cues, provided that mitochondrial outer membrane permeabilization has occurr

209 of Bcl2-associated X protein activation and mitochondrial outer membrane permeabilization in vitro a

210 hondrial division dynamin directly regulates mitochondrial outer membrane permeabilization independen

211 Mitochondrial outer membrane permeabilization is transie

212 itors are elusive, our findings suggest that mitochondrial outer membrane permeabilization may repres

213 and signaling pathway(s) culminating in the mitochondrial outer membrane permeabilization that initi

214 oteins to oligomerization of BAX and BAK and mitochondrial outer membrane permeabilization, an intric

215 hain at the level of complex III, attenuated mitochondrial outer membrane permeabilization, and decre

216 teins are widely known as key controllers of mitochondrial outer membrane permeabilization, arguably

217 rinsic pathway of apoptosis, as evidenced by mitochondrial outer membrane permeabilization, but downs

218 wn acts as a proapoptotic signal that causes mitochondrial outer membrane permeabilization, dissipati

219 ring the cell intrinsic apoptotic pathway is mitochondrial outer membrane permeabilization, leading t

220 This change contributed to mitochondrial outer membrane permeabilization, release o

221 ure of cells to prodeath stimuli, control of mitochondrial outer membrane permeabilization, switch-li

222 Mitochondrial outer membrane permeabilization, which is

223 ember Bid, which, together with Bax, induces mitochondrial outer membrane permeabilization.

224 zmB-truncated Bid, and promotes GzmB-induced mitochondrial outer membrane permeabilization.

225 s that faithfully recapitulate BAX-dependent mitochondrial outer membrane permeabilization.

226 ax activation, Bax homo-oligomerization, and mitochondrial outer membrane permeabilization.

227 ests a process for controlling the degree of mitochondrial outer membrane permeabilization.

228 s, thereby triggering Bak/Bax activation and mitochondrial outer membrane permeabilization.

229 lls, mdivi-1 retards apoptosis by inhibiting mitochondrial outer membrane permeabilization.

230 apoptosis, either upstream or downstream of mitochondrial outer membrane permeabilization.

231 alleviating Bcl-xL-dependent suppression of mitochondrial outer membrane permeabilization.

232 is known about how these interactions impact mitochondrial outer-membrane permeabilization (MOMP) and

233 ated apoptosis as one of the factors causing mitochondrial outer-membrane permeabilization (MOMP).

234 Mitochondrial outer-membrane permeabilization can lead t

235 at shock was RAIDD dependent and upstream of mitochondrial outer-membrane permeabilization.

236 Mitochondrial outer membrane permeabiliztaion (MOMP) was

237 (PC), the most abundant phospholipid of the mitochondrial outer membrane, play a role in the import

238 We identify a phospholipase of the mitochondrial outer membrane, PLD6, as the mediator of M

239 lly as sensitive as CD27-sufficient cells to mitochondrial outer membrane polarization upon exposure

240 zation, but the molecular composition of the mitochondrial outer membrane pore is under debate.

241 ochondrial outer membrane, disruption of the mitochondrial outer membrane potential, and caspase acti

242 The mechanism involves an integral mitochondrial outer membrane protein and general autopha

243 In Arabidopsis (Arabidopsis thaliana), the mitochondrial outer membrane protein DGD1 SUPPRESSOR1 (D

244 l mitochondria and additionally requires the mitochondrial outer membrane protein FIS1, the autophagy

245 The stable ectopic expression of a mitochondrial outer membrane protein fused to a GFP:Stre

246 the peripheral benzodiazepine receptor, is a mitochondrial outer membrane protein implicated as essen

247 MitoNEET (mNEET) is a dimeric mitochondrial outer membrane protein implicated in many

248 Here we show that the mitochondrial outer membrane protein Mcp1 functions in t

249 loid leukemia (AML) cells, we identified the mitochondrial outer membrane protein mitochondrial carri

250 The human mitochondrial outer membrane protein mitoNEET is a novel

251 One of these is the novel mitochondrial outer membrane protein MOMA-1.

252 Mitofusin2 (Mfn2) is a mitochondrial outer membrane protein regulating mitochon

253 TOM36 is a trypanosomatid-specific essential mitochondrial outer membrane protein that has been impli

254 Fis1 is a mitochondrial outer membrane protein that recruits the d

255 The mitochondrial outer membrane protein Tom40 is the genera

256 mport of tRNAs requires four subunits of the mitochondrial outer membrane protein translocase but not

257 hown that tubulin dimer interaction with the mitochondrial outer membrane protein voltage-dependent a

258 Here we identify a beta-barrel mitochondrial outer membrane protein, termed tripartite

259 mTOR is in a complex with the mitochondrial outer-membrane protein Bcl-xl and VDAC1.

260 NME3 is a mitochondrial outer-membrane protein capable of interact

261 Mitofusin-2 (MFN2) is a mitochondrial outer-membrane protein that plays a pivota

262 s encoding actin cytoskeleton components and mitochondrial outer membrane proteins also cause accumul

263 These mitochondrial outer membrane proteins contain a GTPase d

264 ase parkin, which builds ubiquitin chains on mitochondrial outer membrane proteins, where they act to

265 Several mitochondrial outer membrane proteins-mitochondrial fiss

266 hese results indicate that remodeling of the mitochondrial outer membrane proteome is important for m

267 rone Hsp70/Hsp90 may function to prepare the mitochondrial outer membrane receptor Tom71 for preprote

268 tified mitochondrial fission factor (MFF), a mitochondrial outer-membrane receptor for DRP1, the cyto

269 tal signals, BAX and/or BAK permeabilize the mitochondrial outer membrane, resulting in cytochrome c

270 hosphorylated JNK (p-JNK) interacts with the mitochondrial outer membrane SH3 homology associated BTK

271 irst identified Fe-S protein anchored in the mitochondrial outer membrane, strictly depends on ISC ma

272 consider that Bax and Bak form pores at the mitochondrial outer membrane that are responsible for th

273 ion channel (VDAC), the major channel of the mitochondrial outer membrane that controls most of the m

274 amide forms large and stable channels in the mitochondrial outer membrane that induce cell death thro

275 SAM complex is an essential component of the mitochondrial outer membrane that mediates the insertion

276 ff), a tail-anchored membrane protein of the mitochondrial outer membrane that recruits Drp1 to sites

277 t of beta-barrel precursor proteins into the mitochondrial outer membrane: The translocase of the out

278 beling revealed that EXD2 is anchored to the mitochondrial outer membrane through a conserved N-termi

279 substrates and adenine nucleotides cross the mitochondrial outer membrane through the voltage-depende

280 apoptosis relies on permeabilization of the mitochondrial outer membrane to factors such as cytochro

281 the mitochondria, where it inserts into the mitochondrial outer membrane to form a toxic pore.

282 where it oligomerizes and permeabilizes the mitochondrial outer membrane to promote apoptosis.

283 nitiation of apoptosis by permeabilizing the mitochondrial outer membrane to small proteins, includin

284 ria, we show that PS is transferred from the mitochondrial outer membrane to the inner membrane indep

285 ssion of mitoNEET, a protein residing in the mitochondrial outer membrane, to probe its impact on mit

286 oteins to the peripheral and channel-forming mitochondrial outer membrane translocases (TOMs).

287 oteins to the peripheral and channel-forming mitochondrial outer membrane translocases (TOMs).

288 factors that can inhibit pro-apoptotic BCL-2 mitochondrial outer membrane translocation and oligomeri

289 egin the importation process by crossing the mitochondrial outer membrane via a specialized protein i

290 metric dimers that coalesce to perforate the mitochondrial outer membrane via an unknown mechanism.

291 ls to form pores of unknown structure on the mitochondrial outer membrane via homooligomerization.

292 MitoNEET is anchored to the mitochondrial outer membrane via its N-terminal alpha he

293 Starting at 4 hours, the mitochondrial outer membrane was significantly permeabil

294 lipid mixtures that mimic the composition of mitochondrial outer membranes, we show that functionally

295 ol or mimicking the lipid composition of the mitochondrial outer membrane were tested, we did not det

296 des a 12-kDa protein, which localizes to the mitochondrial outer membrane when expressed in mammalian

297 PIGBOS localizes to the mitochondrial outer membrane where it interacts with the

298 amers, Drp1 is recruited by receptors on the mitochondrial outer membrane, where it further assembles

299 egion (UTR) that confers localization to the mitochondrial outer membrane, which is postulated to aid

300 We have shown that UBP27 is embedded in the mitochondrial outer membrane with an Nin -Cout orientati