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1 logenetic origins (the nucleus, plastid, and mitochondrion).
2 ea and endosomes) and late stationary phase (mitochondrion).
3 endogenous expression of this peptide on the mitochondrion.
4 ion of redox marker genes of the cytosol and mitochondrion.
5 and limited repair mechanisms present in the mitochondrion.
6 in silico role of glycolytic enzymes in the mitochondrion.
7 s across the two membranes that surround the mitochondrion.
8 trated that the SLO3-GFP is localized to the mitochondrion.
9 ondrion of Plasmodium falciparum and a human mitochondrion.
10 oxygen species stress generated by a (proto) mitochondrion.
11 dox homeostasis are intimately linked in the mitochondrion.
12 s of E. coli to anticipate challenges to its mitochondrion.
13 th poorly defined function in the eukaryotic mitochondrion.
14 n T-tubules and ultimately surrounding every mitochondrion.
15 parate pathways, one of which resides in the mitochondrion.
16 ty, and recruits Parkin to the dysfunctional mitochondrion.
17 e lipoylated proteins reside in the parasite mitochondrion.
18 sion and degradation of the damaged daughter mitochondrion.
19 main (TMD) that localizes the protein to the mitochondrion.
20 inkage map spanning all 12 autosomes and the mitochondrion.
21 etic state or to the respective size of each mitochondrion.
22 g c-type cytochrome proteins in the parasite mitochondrion.
23 acid complexes at the inner membrane of the mitochondrion.
24 nsertion/deletion RNA editing process in its mitochondrion.
25 the main ADP/ATP carrier in the trypanosome mitochondrion.
26 F(1)-ATP synthase, for ATP production in the mitochondrion.
27 d in tRNA binding and translocation into the mitochondrion.
28 hat TbCAE is located both in the cytosol and mitochondrion.
29 zation of all but one of the subunits to the mitochondrion.
30 ctive DNA methyltransferases targeted to the mitochondrion.
31 rfamily that is localized exclusively to the mitochondrion.
32 ased oxidative and nitrosative damage to the mitochondrion.
33 three compartments: cytosol, chloroplast and mitochondrion.
34 at the dNTP pool asymmetry arises within the mitochondrion.
35 t on the trapping and extraction of a single mitochondrion.
36 ar circuit initiating and culminating in the mitochondrion.
37 ing ribosome have not been identified in the mitochondrion.
38 or NCX-9 in handling calcium exchange at the mitochondrion.
39 ensive model of Fe/S protein assembly in the mitochondrion.
40 ry increase in oxidative phosphorylation per mitochondrion.
42 ction of the genome revealed an average size mitochondrion (459,678 nt) with relatively little repeti
43 artners--the plastid (a cyanobacterium), the mitochondrion (a proteobacterium), and its host (an arch
44 , we have targeted cytosolic proteins to the mitochondrion, a poly(A) specific 3' exoribonuclease, mt
51 e Drp1, which assembles in a ring around the mitochondrion and appears to constrict both outer and in
53 ionase, whereas its catabolism occurs in the mitochondrion and couples to the energy-yielding electro
55 -1 cells resulted in its accumulation in the mitochondrion and downregulation of functional ATP6 prot
56 p1 mediates fission, and interaction between mitochondrion and endoplasmic reticulum (ER) enhances fi
58 fied TbPSD as type I PS decarboxylase in the mitochondrion and found that it is processed proteolytic
59 has been shown to function primarily at the mitochondrion and is an important regulator of neuronal
60 is located in the intermembrane space of the mitochondrion and is imported via the Mia40 disulfide re
61 se 1, LipL1, has been shown to reside in the mitochondrion and it catalyses the lipoylation of the H-
63 veal that PtdEtn is produced in the parasite mitochondrion and parasitophorous vacuole by decarboxyla
64 lant species, that MSH1 functions within the mitochondrion and plastid to influence organellar genome
65 e need to transport intermediates out of the mitochondrion and reducing the loss of intermediates to
66 y model the squeezing of the largely tubular mitochondrion and show that proteins and conical lipids
67 namics and inextricably link the fate of the mitochondrion and that of the host eukaryote, as exempli
69 one arm buried in the inner membrane of the mitochondrion and the orthogonal arm protruding about 10
70 hese intimate relationships have yielded the mitochondrion and the plastid (chloroplast) - the ancien
71 lls, mitoNEET receives its clusters from the mitochondrion and transfers them to acceptor proteins in
72 bacterial endosymbiont that gave rise to the mitochondrion and was the source of the mitochondrial ge
73 oteins are regulated by microRNAs inside the mitochondrion and whether subcellular spatial location o
75 n cell compartments, favoring the cytoplasm, mitochondrion, and endoplasmic reticulum at the expense
76 OM64, and AtTPR7 reside in the chloroplast, mitochondrion, and endoplasmic reticulum of Arabidopsis
79 NA species or editing in the single T. cruzi mitochondrion are linked to differentiation by a yet-unk
80 east and mammalian tumor cells implicate the mitochondrion as a target of artemisinins, and treatment
81 y Ca(2+), which were confirmed in the intact mitochondrion as well as cellular and in vivo systems.
82 presence of lower glycolysis pathways in the mitochondrion, as well as differences between P. tricorn
84 um ATP synthase is localized to the parasite mitochondrion, assembled as a large dimeric complex, and
86 ntial and may in concert with the identified mitochondrion-associated apoptosis inducing factor (AIFM
87 racil auxotrophy by genetically deleting the mitochondrion-associated DHODH of T. gondii (TgDHODH) fa
88 e interface between the mitochondria and the mitochondrion-associated endoplasmic reticulum (ER) memb
89 iral NS3/4A protease cleavage of MAVS on the mitochondrion-associated endoplasmic reticulum (ER) memb
90 ty of 3betaHSD2 and its association with the mitochondrion-associated ER membrane (MAM) and mitochond
94 ducing factor (AIF) and AMID (AIF-homologous mitochondrion-associated inducer of death) are flavoprot
96 itochondrial destabilization, generating the mitochondrion-associated ligands that activate the NLRP3
97 ioesterase superfamily member 2 (Them2) is a mitochondrion-associated long-chain fatty acyl coenzyme
98 e physically linked to mitochondria known as mitochondrion-associated membranes (MAM), and to mitocho
102 The nature of the host that acquired the mitochondrion at the eukaryote origin is an important mi
105 subsequent degradation of the dysfunctional mitochondrion before it causes activation of cell death.
106 a new model in which cristae within the same mitochondrion behave as independent bioenergetic units,
107 editing at the cob-908 site is necessary for mitochondrion biogenesis, cell division, and plant growt
108 vidence for Fancd2 as a crucial regulator of mitochondrion biosynthesis, and of a molecular link betw
109 e enzymes were localized to the cytoplasm or mitochondrion, but most were dually localized to both ce
110 The probe is targeted to the matrix of the mitochondrion by an alkyltriphenylphosphonium lipophilic
111 D) quantitative visualization of a mammalian mitochondrion by coherent x-ray diffractive imaging (CXD
112 ge between the endoplasmic reticulum and the mitochondrion, by increasing interaction with a macromol
114 es are clear: the number of MCU channels per mitochondrion can be calculated, and MCU probability is
115 that different cristae within the individual mitochondrion can have disparate membrane potentials and
116 al for ongoing viability through the female, mitochondrion-carrying line of sexual reproduction in P.
117 s from our and other groups suggest that the mitochondrion-centred hypometabolism is a key feature of
119 In the pathogenic bloodstream stage, the mitochondrion consumes ATP to maintain an energized stat
120 owth conditions, Vps13 localizes to endosome-mitochondrion contacts and to the nuclear-vacuole juncti
121 er, rather than being degraded by lysosomes, mitochondrion-containing autophagosomes are released fro
122 sible evolutionary sequence giving rise to a mitochondrion-containing eukaryotic cell from an endosym
125 thesis pathway whose enzymes localize to the mitochondrion, cytosol, or apicoplast, a nonphotosynthet
126 ated the crucial role of plastid-cytosol and mitochondrion-cytosol malate transporters in recycling t
128 lux distribution for lower glycolysis in the mitochondrion depended on which transporters for TCA cyc
134 we observed that cell-cell contact induces a mitochondrion-dependent increase in intracellular calciu
135 al location signal sequence, which undergoes mitochondrion-dependent posttranslational cleavage.
137 one-carbon metabolism, resulting in reduced mitochondrion-derived one-carbon units needed for de nov
139 eta but not PDGFRalpha, reduced the level of mitochondrion-derived reactive oxygen species, which are
142 mbly factors impinging the biogenesis of the mitochondrion-encoded catalytic core subunit 2 (COX2) re
143 iquely possesses heterologous, nucleus-, and mitochondrion-encoded cytochrome c maturase systems.
144 membrane protein, mediates the insertion of mitochondrion-encoded precursors into the inner mitochon
150 ree complementary genes from the nucleus and mitochondrion, establishing a link between genetic drift
151 g active replication in both the nucleus and mitochondrion, even in the absence of exogenous damage.
152 encoded by the maternally inherited parasite mitochondrion, even outcrossing with wild-type strains c
153 ted from healthy components in an individual mitochondrion, followed by mitochondrial fission and deg
154 nduced silencing complex constituents in the mitochondrion for functional mitomiR translational regul
156 oenzyme shift that diverts pyruvate into the mitochondrion for the final steps of glucose oxidation.
159 irulence by protecting the parasites against mitochondrion-generated oxidative stress and by initiati
160 E. coli mutations that stress the C. elegans mitochondrion genetically interact with C. elegans mutat
161 infer that the host that engulfed the proto-mitochondrion had some eukaryote-like complexity, which
164 , imports about a thousand proteins into the mitochondrion; however, the mitochondrial protein import
165 PCR and sequencing of the D-loop of the mitochondrion identified 32 different haplotypes among 1
172 Cardiolipin, a phospholipid specific to the mitochondrion, interacts with the small electron transfe
173 ecifically at the endoplasmic reticulum (ER)-mitochondrion interface, referred to as the mitochondrio
175 e, we show that this necrosis pathway is not mitochondrion-intrinsic but results from an inter-organe
177 ub of cellular metabolism and signaling, the mitochondrion is a crucial organelle whose dysfunction c
188 r component analysis of variants showed that mitochondrion is the most important organelle for hypoxi
189 onditions, carbohydrate oxidation inside the mitochondrion is the primary energy source for cellular
190 cell and number of mitochondrial genomes per mitochondrion, is an indirect biomarker of mitochondrial
192 Fe trafficking away from the cytosol to the mitochondrion, leading to a cytosolic Fe deficiency.
194 neous redox signals in neurons at the single mitochondrion level where transients of glutathione oxid
197 lles, known as hydrogenosomes, mitosomes, or mitochondrion-like organelles, are typically reduced, bo
198 protein (pUL37x1), which is the potent viral mitochondrion-localized inhibitor of apoptosis (vMIA), t
199 -1 was strongly enhanced by depletion of the mitochondrion-localized, GSH-dependent persulfide oxygen
203 artemisinin resistance and suggest that the mitochondrion may be an important target of inhibition o
204 uttles between the chloroplast, cytosol, and mitochondrion may play a significant role at low light l
206 ce (DeltaPsim) was altered and modulation of mitochondrion-mediated apoptosis regulating genes change
212 allele, might also lead to the peroxisome-to-mitochondrion mistargeting of AGT, a suggestion that has
213 dox misbalance does not significantly affect mitochondrion morphology or the activity of respiratory
214 m the host cell to the extracellular matrix, mitochondrion morphology radically changes, resulting in
216 r of Type III cells also exhibit an atypical mitochondrion near the presynaptic vesicle clusters at t
217 of CRMP5 expression at later stages enhanced mitochondrion numbers in cultured neurons, suggesting th
220 2 plasmids from bacteria, the apicoplast and mitochondrion of Plasmodium falciparum and a human mitoc
223 of the thiol redox homeostasis in the single mitochondrion of these parasites has remained largely un
225 r type I nitroreductase (NTR) located in the mitochondrion of trypanosomatids and, at the same time,
230 les in the phloem, such as plastid, vacuole, mitochondrion, or endoplasmic reticulum, interact with s
231 ge in the fluorescent state of an individual mitochondrion, "oscillation" to refer to a localized cha
232 y identified regions of coupling between the mitochondrion outer membrane and the parasite pellicle,
233 vators of SIRT1 (resveratrol or SRT1720) and mitochondrion oxidation consumption rate and immunoblot
236 hanges in net pro-apoptotic signaling at the mitochondrion ("priming") induced by chemotherapeutic ag
238 n is a negative transcriptional regulator of mitochondrion-related nuclear genes and genes encoding s
239 myclobutanil, the expression of five of six mitochondrion-related nuclear genes was down-regulated.
241 olutionary continuum that includes anaerobic mitochondrion-related organelles (MROs), such as hydroge
244 tis ISC system function within its anaerobic mitochondrion-related organelles and can functionally re
246 cking of CFTR from intracellular vesicles in mitochondrion rich cells to the plasma membrane in the g
253 s TWINKLE, SSBP1, and TFAM, all of which are mitochondrion-specific DNA effectors and are known to fu
256 Our results support the hypothesis that the mitochondrion-specific lipid cardiolipin functions as a
257 s (i.e. the BCL2 homology 3 ligand cBID, the mitochondrion-specific lipid cardiolipin, and membrane g
258 ted with the formation of a complex with the mitochondrion-specific phospholipid cardiolipin (CL), le
259 d co-localization of PNKP and NEIL2 with the mitochondrion-specific protein cytochrome c oxidase subu
263 glutathione, and the regulation of ROS as a mitochondrion-STAT3-dependent pathway in Ras-transformed
264 e: a majority of axon fragments containing a mitochondrion survive axotomy, whereas those lacking mit
265 d Hep G2 cell lines expressing predominantly mitochondrion-targeted (Mt(++)) CYP2E1 and livers from a
266 emerged as the prototype of a novel class of mitochondrion-targeted agents that deplete cardiolipin a
267 s responsible for MICU1 phosphorylation, and mitochondrion-targeted Akt strongly regulates the mitoch
268 uro-2A cells stably expressing predominantly mitochondrion-targeted CYP2D6 were more sensitive to MPT
272 FOXO-mediated transcriptional activation of mitochondrion-targeted nuclear genes in concert with red
273 c approach, we characterized the role of the mitochondrion-targeted PPR78 protein in nad5 mature mRNA
274 t of innate immunity and supports the use of mitochondrion-targeted ROS scavengers as potential adjuv
276 in the parasite, one of which resides in the mitochondrion (TgPEPCKmt), whereas the other protein is
279 nt mitochondrial depolarizations in a single mitochondrion that occur in a nonperiodic manner, simula
280 . tricornutum predicts that reactions in the mitochondrion that supply glycerate may support TAG synt
281 flow from the endoplasmic reticulum into the mitochondrion through ryanodine receptors, and the resul
282 thine impairs the ability of the cytosol and mitochondrion to cope with exogenous oxidative stresses,
283 ition to preventing transfer of DNA from the mitochondrion to the nucleus, VPS13 suppresses mitophagy
285 skeletal muscle and liver cells, uptake per mitochondrion varies in magnitude but total uptake per c
286 othelial nitric-oxide synthase (eNOS) to the mitochondrion via a mechanism that requires protein nitr
290 tofluorescence, the metabolic status of each mitochondrion was analyzed following addition of a respi
292 hese results indicate that the origin of the mitochondrion was not a prerequisite for genome-size exp
293 ipid droplets (LDs) in direct contact with a mitochondrion was reduced, and the average distance betw
294 e its yeast counterpart, is localized to the mitochondrion where it adopts an extremely protease-resi
295 ess involves translocation of viperin to the mitochondrion, where it binds the beta-subunit (HADHB) o
296 r eukaryotes Trypanosoma brucei has a single mitochondrion whose single-unit genome is physically con
297 on and increased translocation of Hk1 to the mitochondrion with corresponding heightened ATP synthase
298 D projection image was captured of a similar mitochondrion with the aid of strongly scattering Au ref
299 cess to "colorize" detailed EM images of the mitochondrion with the position of labeled proteins.
300 of differential centrifugation to enrich for mitochondrion within cell extracts prior to DNA extracti