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1 kn]1b/p27, Cdkn1c/p57, and B-cell lymphoma 2-modifying factor).
2               Sex has been implicated as one modifying factor.
3                     Rainfall is an important modifying factor.
4 onset of disease, suggesting the presence of modifying factors.
5 istance airborne transmission (>2 m) and any modifying factors.
6 iable phenotypes suggesting the influence of modifying factors.
7 transcriptional co-regulators, and chromatin-modifying factors.
8 nts previously considered causal may only be modifying factors.
9  known Polycomb proteins and other chromatin-modifying factors.
10  are controlled by powerful genetic risk and modifying factors.
11  relation to major potential confounding and modifying factors.
12 , which could provide a strategy to discover modifying factors.
13 ests the existence of at least two non-ABCA4 modifying factors.
14 ion by P-TEFb involves chromatin binding and modifying factors.
15 at mutation, but is also influenced by other modifying factors.
16 ms of epithelial carcinogenesis and evaluate modifying factors.
17 propriate set of mRNA-processing and histone-modifying factors.
18  as a platform for the assembly of chromatin-modifying factors.
19  to investigate phenotypic heterogeneity and modifying factors.
20  repeat length, however, suggests a role for modifying factors.
21 quential action of DNA-binding and chromatin-modifying factors.
22 ibutions from other genetic or environmental modifying factors.
23 , these variables were examined as potential modifying factors.
24  remainder of the vWF protein and additional modifying factors.
25 isorder caused by mutations in the sulfatase modifying factor 1 (SUMF1) gene.
26 t are activated by another enzyme, Sulfatase-Modifying Factor 1 (SUMF1), whose inactivation in humans
27 tide polymorphism within the gene sulphatase modifying factor 1.
28 acterize this diversity and examine possible modifying factors amongst a large number of individuals
29 ident that for many common chronic diseases, modifying factors amplify disease mechanisms to make the
30 ignificantly mutated genes include chromatin-modifying factors and candidate contributors SPG20, TLR4
31 plexes with chromatin remodeling and histone-modifying factors and cofactors, including the TIP60 his
32 there is a pressing need to identify disease-modifying factors and devise interventional strategies.
33 ncreasing expression of extracellular matrix-modifying factors and lysyl oxidase genes and by facilit
34 o reveal new relationships between chromatin-modifying factors and to create a functional map of the
35 cluded components of methanogenesis, protein-modifying factors, and leucyl-tRNA synthetase (LeuRS).
36 AC to transcription factors (TFs), chromatin-modifying factors, and noncoding RNAs (ncRNAs) in ~4,300
37 the phenotype classification, the search for modifying factors, and the development and evaluation of
38 role of family socioeconomic status (SES) as modifying factor are unclear.
39  weight (EBW) and related diseases and their modifying factors are an unmet research need that may le
40 cycle in a general population, and potential modifying factors are not investigated.
41          One possible reason is that disease-modifying factors are tissue-specific.
42 des both general transcription and chromatin-modifying factors, as well as FRI-specific components su
43  dismutase (MCF+SOD cells) demonstrated dose-modifying factors at 10% isosurvival of 1.8 and 2.3, res
44 in formation involves spreading of chromatin-modifying factors away from initiation points over large
45                                         Bcl2-modifying factor (Bmf) is a member of the BH3-only group
46                                        Bcl-2-modifying factor (Bmf) was differentially upregulated (P
47  mechanism(s) by which insulin prevents Bcl2-modifying factor (Bmf)-induced renal proximal tubular ce
48                                              Modifying factors, both genetic and environmental, must
49         The bromodomain-containing chromatin-modifying factor BRD4 is an inherited susceptibility gen
50 echanism by which three classes of chromatin-modifying factors-Brg1, HDAC and PARP-cooperate to contr
51  occur via directed recruitment of chromatin modifying factors by the master regulator, X-inactive sp
52 en postulated that the loss of an additional modifying factor contributes to the severity of type I S
53 d increased clonogenic radioresistance [dose-modifying factor (DMF), 1.47], reduced apoptotic respons
54 ledge of the role of chromatin and chromatin-modifying factors during DDR in plants with equivalent s
55                                              Modifying factors (e.g., sex, race/ethnicity) and dietar
56 ared genotypes were reviewed for evidence of modifying factor effects.
57         In addition, participants identified modifying factors (eg, insurance coverage) that could ma
58                 In addition, age should be a modifying factor, especially in moderate kidney impairme
59 cluding risk determinants for nonsmokers and modifying factors for smokers.
60 ll remains to identify causative and disease modifying factors for this devastating disease.
61 ts in the gene SUMF1, encoding the sulfatase modifying factor formylglycine-generating enzyme.
62                                              Modifying factors frequently impact the ABCA4 disease ph
63 nce, and the existence of additional genetic modifying factors has been suggested in these diseases.
64 ndividuals, and genomic and/or environmental modifying factors have been evoked to explain these obse
65 scular injury is a well-established, disease-modifying factor in acute respiratory distress syndrome
66 ukin-10 autoantibodies may be a causative or modifying factor in IBD, with potential implications for
67 se data suggest that BBB disruption may be a modifying factor in the development of schizophrenia and
68           This "grace period" may serve as a modifying factor in the epidemiology of this newly emerg
69 se type 2N mutation (R91Q) was excluded as a modifying factor in these groups of patients.
70  in thiamin homeostasis and could serve as a modifying factor in thiamin nutritional deficiency as we
71 isorders implies the existence of additional modifying factors in pathways that can potentially be mo
72 pending on the cellular environment or other modifying factors in the cell.
73 parallel functions for these three chromatin-modifying factors in the regulation of TATA-containing g
74  and transcription factors, as well as novel modifying factors including chromatin remodelers, small
75 mediated by compromised functions of histone-modifying factors, including the enzymes associated with
76  decisions, environmental, psychosocial, and modifying factors influenced screening decisions.
77  the pathogenic pathways and identify new or modifying factors involved in muscular dystrophy, expres
78  law of the minimum, meaning that the output-modifying factor is the signaling protein that is most l
79 and further evidence of the relationship and modifying factors is needed.
80 ilial clustering of phenotypes suggests that modifying factors may influence the clinical manifestati
81  It seems most likely that a small number of modifying factors may radically affect the course of dis
82       Although ER stress can be a cause or a modifying factor of human disease, little is known of th
83 tor-transfected cells, corresponding to dose-modifying factors of approximately 2.0 and 1.5 in the mi
84          In this study, we aimed to identify modifying factors of disease onset in C9orf72 carriers u
85   Future studies will explore the effects of modifying factors on the development of HCC.
86 y concordant effects of the KL-VS allele and modifying factors on the risk of occult CAD were seen in
87  ideal system to monitor the role of disease-modifying factors over a long time.
88               Beyond its role as a chromatin-modifying factor, p300 displays an acetyltransferase-ind
89 luding thrombospondin 1, delta-like 4, BclII modifying factor, phospholipase C, beta 2, adrenergic re
90        Growing evidence for genetic risk and modifying factors, plus strong evidence that only a mino
91 re an excellent model for delineation of the modifying factors postulated to affect human OI phenotyp
92 regions, presumably as a result of chromatin modifying factors recruited to the PBRU.
93                                    Chromatin-modifying factors regulate both transcription and DNA re
94 uses on how chromatin-remodeling and histone-modifying factors regulate gene expression to control ca
95 pression, but our knowledge of the chromatin-modifying factors regulating these events remains incomp
96  did not identify any additional significant modifying factor relationships (estimated blood loss, du
97 t there are many additional risk alleles and modifying factors remaining to be discovered.
98  remodeling, we propose that these chromatin-modifying factors represent auspicious targets for the p
99      These data identify BRG1 as a chromatin-modifying factor required for nucleosome remodeling and
100 o our knowledge, Brg1 is the first chromatin-modifying factor shown to be required for beta-globin re
101                                              Modifying factors such as fluoride and dental hygiene wo
102 te cancer and the effects of confounding and modifying factors, such as age, family history of prosta
103 ered susceptibility of the mutant protein to modifying factors, such as androgen production at pubert
104                                The impact of modifying factors, such as chronic disease and material
105                                              Modifying factors, such as nutrition literacy, individua
106 e NLRP3 inflammasome and the extent to which modifying factors, such as obesity, may augment the infl
107                                    Chromatin-modifying factors that control TPE in yeast have been ex
108 ordinated development, however, must involve modifying factors that enable differentiation and growth
109 scribed, triggering recruitment of chromatin modifying factors that establish and maintain gene silen
110                                   Therefore, modifying factors that explain why only a subset of kidn
111 microbiome derangements may serve as disease-modifying factors that feature detrimental amyloidogenic
112 s with shared genotypes revealed evidence of modifying factors that in several cases resulted in a >
113 tions, HP1 proteins associate with chromatin-modifying factors that in turn cooperate to assemble rep
114 amilies regulate transcription via chromatin-modifying factors, the precise mechanisms underlying gen
115 ntexts that include experiencing racism) and modifying factors-those that can be changed to make it e
116  of transcriptional modulators and epigenome-modifying factors to any genomic site, leading to new in
117     We sought to identify potential response-modifying factors to determine whether specific groups o
118  control, the relative contribution of these modifying factors to the impairments observed in T2DM re
119 oordinates recruitment of RNA- and chromatin-modifying factors to transcription complexes.
120              We show here that the chromatin-modifying factor TRIM28 is highly expressed in double-po
121  the mitochondrial transfer ribonucleic acid modifying factor (TRMU) in a single patient only, presen
122 ease stage, and to exclude height as a known modifying factor, we performed association studies of he
123 a on disease manifestation, progression, and modifying factors, with relevance for counseling of HSP

 
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