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5 that the transcriptional burst frequency is modulated across the stripe to control the mRNA producti
8 NT Neurotransmitters signal through GPCRs to modulate activity of neurons, and changes in such signal
9 Avadomide (CC-122) is a novel oral cereblon-modulating agent with promising activity in non-Hodgkin
11 volatility-dependent partitioning processes modulate airborne SVOC concentrations through interactio
15 ovel insights into how these ABO effects are modulated and have highlighted that ABO group significan
16 reciated pathway by which type 3 immunity is modulated and immune-mediated pathogenesis controlled.
19 Fs and other proteins, that this interaction modulates antiviral signaling via disruption of USP7 int
21 ngs indicate that HuR regulates autophagy by modulating ATG16L1 translation via interaction with circ
23 ck duration, whereas the MeApv-BNST synapses modulate attack frequency, both with no effect on social
26 and its receptors at the plasma membrane to modulate BDNF-dependent gene expression and neuronal den
28 ke disruption in rodents and humans causally modulates beta-amyloid (Abeta) dynamics (e.g., [1-3]).
32 ranslocation of DNA into the capsid could be modulated by a changing mode of protein-protein interact
33 fferent PRC2-chromatin interaction modes are modulated by accessory subunits, oncogenic histone mutat
34 For PP2A-B56, these patterns are further modulated by affinity and position of B56 binding motifs
36 ve from current locations were independently modulated by changes in both foreground and background r
37 ost synthetic lethal phenotypes are strongly modulated by changes in cellular conditions or genetic c
38 n visual cortex, responses to a stimulus are modulated by context, the visual scene surrounding the s
39 that the nucleosome barrier to TF binding is modulated by dynamic nucleosome unwrapping governed by A
41 whereby features of the channel pore can be modulated by exogenous drugs that bind outside the pore.
42 PDAC mouse model in which CAF plasticity is modulated by genetic depletion of the transcription fact
44 ntation of complex visual scenes that can be modulated by higher-level cognitive systems according to
45 sion of IL-3R on activated human Th cells is modulated by IL-4, and IL-3 regulates the effector funct
48 with proliferation and nutrient sensing are modulated by metformin-regulated miRNAs and that some of
50 veal a mechanism in which gamma-secretase is modulated by neuroinflammation via IFITM3 and the risk o
54 CL1/3/4/5/XCL1); and T(M) chemokine profiles modulated by persisting viral Ags exhibit both discrete
55 nce that describes the variety of mechanisms modulated by ROS that trigger cytoprotective detoxificat
56 he expression of genes in the liver that are modulated by several nuclear receptors, including peroxi
58 binding properties of these receptors can be modulated by the coordinated metal fragments and that th
61 hat accessibility to all positions tested is modulated by the presence of substrates, with the majori
62 ponses in the ventral intraparietal area are modulated by the task reference frame, such that populat
63 limate-related impacts will be substantially modulated by the time evolution of the pattern of SST wa
64 neuronal fate selector function of GATAs is modulated by their cofactors to refine the differentiati
70 iately after the extinction training session modulated c-Fos expression on a retention test in the ve
73 termine general de novo m(6)A deposition and modulate cell type-specific m(6)A patterns, and we discu
74 rehensive drug-sensitivity screening in PP2A-modulated cells to evaluate the functional impact of PP2
77 ced apoptosis in CD4(pos)CD8(pos) thymocytes modulates cellular immunity against PRRSV and other path
78 ood detection and genetic sex to dynamically modulate chemoreceptor expression and influence the feed
83 Changes in overall charge of the complex modulate contrast enhancement, especially of the kidneys
84 a mechanism distinct from other factors that modulate CoV entry.IMPORTANCE Virus entry into host cell
86 findings indicate a pivotal role for LDH in modulating cytokine-mediated T cell differentiation and
87 , emerging nano-strategies that specifically modulate different cell populations of the TME, such as
89 escribed herein suggest that F. virguliforme modulates divergent infection profiles through transcrip
90 d the mechanisms through which HCV infection modulates donor-specific T cell responses following LT a
94 A motifs have versatility in their G-protein-modulating effect, i.e. they can bind to Galpha subunits
96 ogenic functions, but whether PPARbeta/delta modulates endothelial cell metabolism to support the dyn
97 reatic enhancers, suggesting that these SNPs modulate enhancer activity and, consequently, gene expre
98 Here we investigate whether retinal inputs modulate entrainment to nonphotic cues such as time-rest
103 microbial taxa, potential relations between modulating factors, as well as model selection uncertain
104 n of sediment and contaminated material, and modulates fluxes of carbon through Earth's largest terre
107 revealed that the distal leg muscles rapidly modulate force and work output to minimize perturbations
108 was weakened, and the two motifs combined to modulate fusiform cell output and acoustic-driven respon
110 ad mechanism that allows the cell to rapidly modulate gene expression in order to provide flexibility
111 ations, we show that enCRISPRa and enCRISPRi modulate gene transcription by remodeling local epigenet
112 ting contributes to transcript diversity and modulates gene expression in a dynamic, cell type-specif
113 boreal peatlands are important ecosystems in modulating global biogeochemical cycles, yet their biolo
116 tely affect the release of kisspeptin, which modulates gonadotropin-releasing hormone (GnRH) release
117 ein whose absence causes FXS, differentially modulates HCN channels in CA1 versus L5 PFC dendrites.
119 phenotypes in the R6/2 mouse model of HD and modulate HD-associated changes in transcription and epig
121 In murine cells, we show that Ifit1b can modulate host translation and restrict WT mouse coronavi
123 t, based on previous outcomes, rats flexibly modulate how expectations influence their decisions.
124 innervation of numerous organs now known to modulate immune cell function and therefore dictate immu
125 s work has shown that activity in the STN is modulated in a rhythmic pattern when Parkinson's patient
127 ropic effects on hMSC reparative activities, modulating in vitro cytokine secretion and in vivo gene
129 pro-inflammatory or reparative phenotypes to modulate inflammatory and reparative responses, respecti
131 ortant mechanism by which metabolic activity modulates inflammatory signaling through the NF-kappaB p
132 erpinning how substitutions in this position modulate inhibitor efficiency and substrate specificity
133 MEM33 and TMED1 to form a complex capable of modulating innate immune signalling through the cGAS-STI
134 udiciously pre- and post-selecting frequency-modulated input and output optical states in a nearly or
135 remodels neuronal signaling to coordinately modulate intestinal physiology and stress-responsive beh
139 -to-refed transition, glycosylation of SIRT1 modulates its interactions with various transcription fa
141 ding to A kinase anchoring protein (AKAP) 1, modulating its localization to mitochondria and its inte
142 ar bone loss as histologically observed, and modulated key bone remodeling and inflammatory mediators
145 in the mammary gland, whereby stromal ACKR2 modulates levels of the shared ligand CCL7 to control th
146 serve as a substrate buffer or reservoir to modulate lipid, catecholamine, and iron availability.
149 , probably through signalling by microbially modulated metabolites to neurons in the developing brain
150 rt that the IKK2/NF-kappaB signaling pathway modulates metastasis-associated protein 2 (MTA2), a comp
151 is study aimed to elucidate whether N1 could modulate microglial function and, if so, determine the c
152 al thickness and cellular densities may also modulate MSC-derived chondrocyte hypertrophy in vitro.
153 h or survival decisions in plant immunity by modulating multiple stress-responsive processes in this
155 tivation of the kappa opioid receptor system modulates negative affect and dysphoria, but recent stud
156 c Nrxn1alpha disruption and changes in value-modulated neural activity, we reveal potential neural su
158 c transmission; consequently, an interaction modulating nociception could exist between oxytocin and
160 ing of this local pool at each cell division modulates nuclear growth kinetics and dictates size scal
161 he relaxed (R) or tense (T) quaternary state modulates O(2) delivery to hypoxic (FME) and normoxic (L
163 SGC Gq-coupled receptor (Gq-GPCR) signaling modulates pain sensitivity in vivo using Gfap-hM3Dq mice
164 Ultimately, these results suggest that, by modulating parasite transmission, community assembly can
167 receptors (GPCRs) are membrane proteins that modulate physiology across human tissues in response to
168 tial variation in soil microbial communities modulates plant species' distributions remains largely u
169 he phase difference between two harmonically modulated polarised laser beams - an 'object beam' that
170 , these experiments demonstrate that ACh can modulate population-level granule cell responses by alte
173 which bind specific RNA-target sequences and modulate pre-mRNA splicing by sterically blocking the bi
174 show that 3D head-orienting movements (HOMs) modulate primary visual cortex (V1) activity in a direct
176 on in sensory areas, but how prior knowledge modulates processing higher up in the cortical hierarchy
177 opment of tools through which the ISR can be modulated promises to uncover new avenues to diminish pa
178 ll be key for developing novel approaches to modulate protective and pathological T cell responses in
179 view that global RNA structure significantly modulates protein-RNA interaction dynamics and can facil
186 support roles for heme oxygenase isoforms in modulating recovery from synaptic injury in SIV infectio
187 study, we identified the C. jejuni butyrate-modulated regulon and discovered that the BumSR two-comp
188 ific antibodies and, on prolonged treatment, modulated rejection-related gene-expression patterns.
189 ntriguing pathway to explore with respect to modulating responses against autoantigens and alloantige
190 inal microbiota is thought to play a role in modulating risk of high-risk human papillomavirus (hrHPV
191 PS linkages in the DNA gap was sufficient to modulate RNase H1 cleavage patterns and combining these
193 providing evidence that complement function modulates SARS-CoV-2 infection outcome, the data point t
200 lidated previously uncharacterized RBPs that modulate stress granule abundance, highlighting the appl
204 ppear to deploy an energy-saving strategy by modulating taking-off, their most energetically expensiv
205 f enCRISPRa to oncogenic TAL1 super-enhancer modulates TAL1 expression and cancer progression in xeno
207 results uncover the existence of an arousal-modulated thalamo-corticothalamic loop that links the PV
208 covalent modifications of cysteine thiols to modulate the activities of regulatory kinases and phosph
209 o suggests that conformational switching may modulate the assembly of CD81-partner protein networks.
212 hiometry and regulation of SHR transcription modulate the division timing of two different specialize
214 II)); we used this unique feature to further modulate the electrostatic environment around the Fe-oxi
215 the heart tissue due to the contraction can modulate the excitation, a phenomenon referred to as mec
218 To investigate how these processes jointly modulate the function of the folate stress-sensing Fusob
220 regard, at the cortical level, oxytocin can modulate the GABAergic transmission; consequently, an in
222 s review focuses on therapeutics that aim to modulate the gut microbiota and the gut-liver axis.
223 is study showcases how strain can be used to modulate the hydrogen absorption capacity and HER activi
224 hts into how gastric cancer derived exosomes modulate the immune response to promote lung tumor metas
225 te changes in the nature of the spacer could modulate the intramolecular BP/Thy photoreactivity, resu
227 to be a direct target of miR-128 and able to modulate the methylation status of the pivotal VSMC gene
228 opens up new opportunities to administer and modulate the mobility of transition metal catalysts in l
230 tence stimulating peptide 1 (CSP1) failed to modulate the onset kinetics of competence development in
231 mice; through these effects they critically modulate the organization of hypothalamic feeding circui
232 xed-valent Cu acts as an effective dopant to modulate the oxygen vacancy (V(O) ) concentration and Ti
235 ICANCE STATEMENT G-protein-coupled receptors modulate the release machinery, causing long-lasting cha
236 ied fruits may synergistically contribute to modulate the risk of cardiometabolic and other non-commu
237 europathic components, and compounds able to modulate the signal transduction pathways of the cannabi
238 we identified small-molecule compounds that modulate the skeletal muscle channel isoform (RyR1) inte
239 mming motility can be manipulated in situ to modulate the spatial organization, persistence, and infl
240 ent by 12 fold is achieved using pressure to modulate the structure of a recently developed 2D perovs
242 gdorferi induces selected tick proteins that modulate the vector gut microbiota towards an environmen
243 and the electrical charge of the emulsifier modulated the antioxidant effectiveness of sinapic acid
247 ive-site cysteines and of the cap loop which modulates the association reactions of nDsbD with its pa
248 e is to understand how cytoplasmic signaling modulates the cytoskeleton to produce directed growth co
249 induced autophagy in thymic epithelial cells modulates the development of T cells, and PRRSV-induced
250 non thought to rely on contextual processing-modulates the effects of contextual information on emoti
251 s have directly examined how O-GlcNAcylation modulates the efficacy of inhibitory neurotransmission.
252 ggest that sigma1 conformational flexibility modulates the efficiency of reovirus host cell attachmen
257 n effect on value, or, instead, if attention modulates the information most relevant for the goal of
258 e host framework S(2-) anions, which in turn modulates the Li(+) ion potential energy surface, increa
262 miting viral spread.IMPORTANCE HIV infection modulates the surface expression of Tim-3, but the molec
263 ncluding ERK/MAPK-targets like gephyrin, and modulates the synaptic AMPAR/GluR composition both in th
264 between TMD and C-terminal domain (CTD) that modulates the Zn(2+) transport activity of HsZnT8; and t
265 Through direct association with pol II or by modulating the activity of transcription or RNA processi
266 bilities for tuning mutational landscapes by modulating the cellular environment, with implications f
267 thesis, which contributes to fibre length by modulating the developmental transition from rapid cell
268 scle, they do not play a significant role in modulating the frequency of the ionic pacemaker or the a
269 on in response to environmental stresses and modulating the gas exchange necessary for photosynthesis
270 cancer mutations exhibit loss of function in modulating the Hippo pathway, inducing CIP, as well as a
273 ) with thicknesses in the nanometer order by modulating the oxidation state of a film of a conducting
274 e about the role of oxytocinergic mechanisms modulating the pain process at the RAIC level.SIGNIFICAN
275 ody availability, play a significant role in modulating the probability of a bird being infected.
277 esults reported in this study highlight that modulating the size of the central acene ring is a highl
278 R4 might alter the DTX chemo-sensitivity via modulating the TR4/lincRNA-p21/HIF-1alpha/VEGF-A signali
279 aspect was then experimentally validated by modulating the zeta potential of the detection probe by
280 ngth of supramolecular peptide nanofibers to modulate their immunogenicity in the context of immunoth
281 development of several chemical reactions to modulate their membrane permeability and binding affinit
282 er IRE1alpha adapts the ER in TNBC cells and modulates their TME, and whether IRE1alpha inhibition ca
283 E activity and the effect of small molecules modulating their function can be studied with sub-picomo
286 In addition, we show that temperature may modulate these costs and benefits, and contribute to dyn
287 Ubiquitously expressed chromatin regulators modulate these networks, yet the mechanisms governing ho
289 governing afferent responsiveness to dually modulate these processes are not well characterized.
290 F into CLNs after SAH, while suggesting that modulating this draining may offer therapeutic approache
291 As presynaptic inhibition (PSI) is centrally modulated to allow execution of supraspinal motor comman
292 ults demonstrated that protein synthesis was modulated to facilitate protein secretion in macrophages
293 Auxiliary alpha2delta subunits of VGCCs modulate trafficking and biophysical properties of the p
299 hat olig2(+) cells are ENs whose activity is modulated with locomotion, suiting them to participate i
300 tatory and inhibitory transmitter systems in modulating working memory coding in prefrontal circuits.