ライフサイエンスコーパス: modulation

1 levels over various cycles indicate stromal modulation.

2 d by a multifold increase in light intensity modulation.

3 d involves an intramolecular mechanism for q modulation.

4 echanistic rationale for understanding TRPC6 modulation.

5 a concomitant enhancement of transcriptional modulation.

6 citidine, linked to more specific epigenetic modulation.

7 disease processes warrant precise tools for modulation.

8 issue regeneration, wound healing and immune modulation.

9 urther analyzed as a function of the imposed modulation.

10 lean graphene grids through membrane tension modulation.

11 llosteric activation and positive allosteric modulation.

12 odulation than by a null model without value modulation.

13 system could act as an orchestrator of pain modulation.

14 to active sites or exosites or by allosteric modulation.

15 -linked glycans for local and distant immune modulation.

16 ing certain evolutionary behaviours and mood modulation.

17 source with the potential for high-frequency modulation.

18 ies such as virus assembly and innate immune modulation.

19 discuss strategies for their pharmacological modulation.

20 s in epidermal barrier properties and immune modulation.

21 goal, and licking) in sustained slow firing modulation.

22 sult of the emanating effective gate voltage modulations.

23 ng, burst-like events, rather than by steady modulations.

24 device can control significant output power modulation (2.30-2.72 x 10(3) W cm(-2)) with weak mechan

25 Treatment options, including immune modulation and combination immunochemotherapy, are discu

26 n understanding the B. microti biology, host modulation and diverse parasite developmental stages usi

27 esults challenge the prevailing model of OSN modulation and highlight opportunities to better underst

28 or development in macrophage-mediated immune modulation and macrophage-mediated drug delivery, which

29 M2 muscarinic receptors, contributes to the modulation and maturation of NGF, improving the regenera

30 for heme production that enabled controlled modulation and monitoring of labile heme levels, here we

31 ti-CD47 antibody (alphaCD47), for macrophage modulation and reversal of immunosuppression in tumors.

32 n-chip lasing, frequency comb generation and modulation and sensitive molecular detection.

33 ally invasive treatment alternative for scar modulation and volume reduction.

34 fects transmissibility, pathogenesis, immune modulation, and drug resistance.

35 ely controlled by chemical doping, interface modulation, and electrostatic gating, there is as of yet

36 ic devices, and enable signal amplification, modulation, and relay.

37 peutic potential of isoform-selective enzyme modulation are lacking.

38 irect future work exploring potential immune modulation as a novel treatment.

39 These preclinical studies suggest PP(i) modulation as a potential and novel approach for cementu

40 ghlighted the potential for ketone metabolic modulation as a promising treatment paradigm.

41 We thus highlight membrane potential modulation as a tractable tool for modulation of signali

42 However, the symmetry modulation at interfaces and the resultant effects have

43 rate of 10 GHz, which results in temperature modulation at the same frequency with amplitude ~0.1 K.

44 nergy efficient and high-speed electro-optic modulation at the wavelength scale paves a crucial found

45 GC's activity shows robust modulations before animals' contact with tastants, and t

46 nt with global phosphoproteome effects, PP2A modulations broadly affect responses to more than 200 dr

47 The allergy preventive effects of gut immune modulation by bacterial compounds are still not fully un

48 the critical importance of membrane fluidity modulation by desaturases in the adaptive strategies of

49 These increases in modulation by dopamine and noradrenaline likely indicate

50 assay of serotonin transporter function and modulation by drugs.

51 Despite significant modulation by environmental factors, action planning, an

52 e a circuit and synaptic basis of aggression modulation by experience, which can be potentially targe

53 ghly aggressive skin cancer for which immune modulation by immune checkpoint inhibitors shows remarka

54 ruitment to depolarized mitochondria and its modulation by kenpaullone in real time and with single-c

55 represents a paradigm shift in thermal-based modulation-demodulation of digital data, and offers a pr

56 Binding-dependent ERP modulations did not reveal group differences.

57 wo-dimensional electron system confined to a modulation-doped AlAs quantum well.

58 A large spin Hall angle of ~90 in the modulation-doped Cr-BST film is demonstrated at 2.5 K, a

59 ke and behaving mice, and investigated their modulation during a sensory-task, whisker stimulation.

60 tion and presents the first evidence of zinc modulation during egg activation in a non-mammalian spec

61 icate that ZIP9 is essential for proper zinc modulation during zebrafish egg activation and presents

62 The results unraveled different unilateral modulation dynamics of the muscle-synergy activations du

63 characterize important allosteric and enzyme modulation effects.

64 However, correlations between low modulation flicker fusion threshold and reading rate for

65 supporting a functionally relevant feedback modulation from LOC to EVC for scaling size information.

66 ed' neurons exhibited a variety of amplitude modulations from sensory to cognitive, notably by choice

67 Here, by optimizing the modulation geometry and post-processing algorithms, we d

68 dic eye drifts, revealing a continuum in the modulations given by different eye movements, with oculo

69 he Ig-superfamily whose exact role in immune modulation has remained elusive.

70 r, the existence and nature of this putative modulation have never been physiologically demonstrated.

71 We show that parameter modulation impacts the observed points by introducing di

72 nding organocatalysts a greater than 10-fold modulation in binding affinity is achieved upon photoiso

73 t time to our knowledge, we demonstrate this modulation in both the equilibrium and pre-equilibrium e

74 mation with a 7% lattice change and dramatic modulation in chemical, electronic, magnetic and optical

75 merous examples of FOXA-dependent epigenomic modulation in developmental and disease processes.

76 tic activity in vitro and FXR-dependent gene modulation in vivo.

77 ll bunch longitudinal phase space, such that modulations in both planes can be studied simultaneously

78 Most studies have focused on the effects of modulations in goals and kinematics of observed actions

79 ression of Ralpha2 is known to be subject to modulation, information about its transcriptional regula

80 Utrophin modulation is a promising therapeutic strategy for Duche

81 ology, and raise the possibility that immune modulation is a therapeutic option.

82 of a larger pro-inflammatory pathway, whose modulation is also being explored.

83 However, the mechanism of modulation is largely unknown.

84 in SCN neurons, but also reveal that diurnal modulation is not required for time-of-day-specific effe

85 s into B6 mice without any additional immune modulation led to permanent acceptance of F1 skin grafts

86 ndergo remarkably similar activity-dependent modulation manifesting as epochs of enhanced intrinsic e

87 JNK2 modulation may be a novel therapeutic target for atrial

88 rformance, indicating that this differential modulation may be secondary to the motor skill acquisiti

89 These results suggest that TDP modulation may improve clinical outcomes by reducing pai

90 for early intervention and MMP9/RAGE pathway modulation may lead to promising drug targets.

91 ontrolled electronics and established direct modulation mechanism by external mechanical stimuli.

92 light opportunities to better understand OSN modulation mechanisms and their relationship to animal p

93 n = 115, 39.4%), and immune and inflammatory modulation (n = 79, 27.1%).

94 injury, and improved immune and inflammatory modulation (n = 79, 27.1%).

95 Yet similar modulations occur during movement planning when no movem

96 BA(A) receptors in the brain, and studies of modulation of [(3)H]muscimol binding by allosteric GABAe

97 emonstrating the stress-induced conductivity modulation of a perovskite oxide thin film, SrTiO(3), th

98 Modulation of activity duration is impaired in rLG, conf

99 he mammalian axon initial segment (AIS), and modulation of AIS size by recruitment or loss of protein

100 Through the modulation of AKT, B55beta induced the expression of the

101 lity of this technology to provide long-term modulation of allergy in a murine model of cow's milk al

102 contributes to other roles of UL148, such as modulation of alternative viral glycoprotein complexes t

103 Abnormal modulation of Aurora B in interphase leads to cell cycle

104 At the forefront of this effort is the modulation of autoantibody half-life and blocking access

105 the functions of histone acetylation in the modulation of auxin signaling as well as in the regulati

106 Bidirectional modulation of avoidance by PL projections to VS and BLA

107 Modulation of basal cell plasticity may represent a rele

108 These findings highlight the modulation of behavioral state as a powerful independent

109 These findings strongly suggest that TSPAN-7 modulation of beta-cell L-type Ca(V) channels is a key d

110 Negative modulation of both receptors enhanced excitatory glutama

111 simultaneous recording and optical/chemical modulation of brain activities across distant regions.

112 Non-invasive, molecularly-specific, focal modulation of brain circuits with low off-target effects

113 affects intracellular responses through the modulation of Ca(2+) signaling, actin organization, vesi

114 Modulation of Ca(V) 1/Ca(V) 2 channel activity is a powe

115 signaling in mediating spine injury and the modulation of caspase 3 activation may benefit neurons f

116 tion or supplementation of LXA(4) identified modulation of CC-chemokine receptor 7 (CCR7) and sphingo

117 significantly altered the attention-related modulation of CDh neurons and strongly impaired the clas

118 Altogether, these findings indicate that modulation of chronic stress-induced neuronal activity l

119 We propose that modulation of CMU protein levels and microtubule localiz

120 ver, the mechanisms underlying the GSK-3beta modulation of cognitive function via D(2)Rs remains uncl

121 els based on striatal dopamine's topographic modulation of cortico-thalamic connectivity within corti

122 here we demonstrate that this weight-driven modulation of corticospinal excitability is easily suppr

123 diffusion coefficient after one cycle, and, modulation of cycle-specific serum pentraxin 3 levels ov

124 ignaling and cell-cell communication via the modulation of DGK4 activity during the progamic phase of

125 ar to contribute to preventing infection and modulation of disease severity.

126 Translation of modulation of drug target activity to therapeutic effect

127 ch dimensionality regulation is possible via modulation of electrical coupling through the gap juncti

128 agreement, correlating linker rotation with modulation of emission.

129 ecifically inhibits Salmonella infection via modulation of endolysosomal trafficking and the vacuolar

130 molecules that are conserved with respect to modulation of expression.

131 and uncovers new targets for the therapeutic modulation of ferroptosis.

132 t endothelial Dhh both opens the BBB via the modulation of forkhead box O1 (FoxO1) transcriptional ac

133 thodology that affords bidirectional, graded modulation of gene expression enabled by tiling the prom

134 on studies using protein-coding cDNAs to the modulation of gene expression using small RNA therapeuti

135 g the role of dedicated AMPK subunits in the modulation of gene expression.

136 e competent Cas9 protein for transcriptional modulation of genes, allowing multifunctionality of CRIS

137 The modulation of GLI2, an oncogenic transcription factor co

138 NS1 contributes to placental dysfunction via modulation of glycosaminoglycans on trophoblasts and cho

139 ocal sensing of morphogen levels with global modulation of gradient spread.

140 Importantly, this rest-task modulation of GSCORR could be traced to transient coacti

141 have an afferent role in microbiota-mediated modulation of gut sympathetic neurons.

142 ion of meiotic STAG3 cohesin complex and the modulation of heterochromatin formation in spermatocytes

143 These data indicate that the modulation of heterologous immune responses is induced b

144 ous research has demonstrated that selective modulation of hippocampal transmission by systemic admin

145 Thus, the modulation of host cell signaling pathways by papaverine

146 intenance of algae, as well as in the immune modulation of host coral cells.

147 acids traffic extracellularly to trigger the modulation of host immune responses.

148 potential pharmaceuticals to be utilized in modulation of HSC activity and bone marrow transplantati

149 intrinsic functional networks and the causal modulation of human behaviour and experience with iES.

150 eir binding to allergens or their autonomous modulation of immune receptors.

151 establishment of an intracellular niche, and modulation of immune responses.

152 replenishment of youthful gut microbiome via modulation of immunologic, microbial, and metabolomic pr

153 genous targeted mRNAs and their relevance to modulation of in vivo tissue dynamics remain elusive.

154 This bidirectional modulation of inhibition is abolished when the function

155 y and controls germination responses through modulation of its cell wall mechanical properties.

156 onic miRNA and their host transcripts in the modulation of key signaling pathways and disease progres

157 The suppression of the KChIP3-mediated modulation of Kv4.2 channels was weaker for the JNCL-rel

158 ts that individuals with ASD evince atypical modulation of LC activity in accordance with changes in

159 gest that individuals with ASD show atypical modulation of LC activity with changes in attentional de

160 In the last decade voltage modulation of ligand-induced GPCR activity has been repo

161 Trained innate immunity, induced via modulation of mature myeloid cells or their bone marrow

162 C9s is in part BATF-dependent and occurs via modulation of metabolic transcriptional programs.

163 NAM binding kinetics and negative allosteric modulation of mGlu(5) receptor internalization and adds

164 brane resistance (DeltaPsim) was altered and modulation of mitochondrion-mediated apoptosis regulatin

165 nfined neural stimulation of mouse brain and modulation of motor activity in vivo.

166 -mediated defensive response against HLB via modulation of multiple hormonal pathways.

167 now implicate the kappa opioid system in the modulation of negative affect associated with pain.

168 ggesting possible engagement of ACh-mediated modulation of neural activity in the MNTB.

169 Optical technologies allowing modulation of neuronal activity at high spatio-temporal

170 or an additional layer of activity-dependent modulation of neurotransmission.

171 ol) can increase stressor engagement through modulation of neurotransmitter systems and are used to i

172 tion, potentially by means of Fli-1-mediated modulation of NF-kappaB signaling.

173 mic alpha-klotho/FGFR1/PI3K signaling in the modulation of NPY/AgRP neuron activity and maintenance o

174 reveal a receptor-mediated mechanism for C1q modulation of NSC behavior and show that modification of

175 easurements fail to capture the viscoelastic modulation of nuclear stress-strain relationships by the

176 nd insulin signaling in starvation-dependent modulation of olfactory sensory neuron (OSN) function in

177 Here, we examined DA modulation of olfactory transmission in lampreys.

178 However, a specific modulation of other distinct physiological or pathologic

179 The effects of a systematic modulation of oxygen over-stoichiometry of VO(2) from 1.

180 lation system, manifested by the attentional modulation of pain ratings and enhanced pain responses i

181 Continuous, stimulus-driven modulation of phase stabilities remains a significant ch

182 Therefore, modulation of phase-referenced chunking of information i

183 confidence in a decision leads to a striking modulation of post-decision neural processing, such that

184 These data support a model in which the modulation of PP-InsPs influence the ESR through general

185 The modulation of PPIs presents opportunities to gain mechan

186 suggesting a significantly altered cortical modulation of primary afferents.

187 y field as it can be useful not only for the modulation of properties in zwitterionic compounds but a

188 Thus, PIPKIgammai5 is critical for the modulation of Rab7a activity, localization, and function

189 ative proportion of symbiotic interfaces via modulation of RAM1 However, the overexpressors also show

190 to identify targets for the pharmacological modulation of related pathologic behaviors.

191 ct of posttranslational modifications in the modulation of reversible amyloids.

192 c effect of lithium suggests that a targeted modulation of reward learning may be a viable approach f

193 Second, we examined dopaminergic modulation of reward magnitude effects on temporal disco

194 Thus, CD33rSIGLEC modulation of ROS likely contributes to maximum reproduc

195 xpansion of HSPCs during development through modulation of RUNX1 activity.

196 This review addresses the modulation of RyR1 and RyR2, in addition to the impact o

197 Using spatial modulation of S1P provision and signaling, we demonstrat

198 Supporting this, modulation of SASH1 levels in a panel of lung cancer cel

199 potential modulation as a tractable tool for modulation of signaling cascades that rely on calcium as

200 ect atherosclerosis by regulating phenotypic modulation of SMC.

201 n both male and female mice reveal selective modulation of SST interneurons and a putative downstream

202 signals, a bottom-up method involves direct modulation of stem cell behavior without relying on the

203 ABA and the light signaling component in the modulation of stomatal movement.

204 ing a possible role in knee joint injury and modulation of such by altering muscular strength.

205 combining a simple solution processing with modulation of surface composition, is described.

206 ion remains as to whether adjuvant-dependent modulation of T(fh) cells enhances HIV-1 vaccine-induced

207 lated before fragmentation, which results in modulation of the abundance of their fragments.

208 ations, was utilised to simulate and examine modulation of the activation dynamics of molecules withi

209 tro multiplex reporter system that evaluates modulation of the activity of 46 transcription factors;

210 Modulation of the activity of nNOS-expressing neurons dr

211 Modulation of the amplitude, duration, and duty cycle of

212 havioral changes in mice were phenocopied by modulation of the circadian system with drugs that targe

213 molecular dynamics simulations suggest that modulation of the electrostatic environment due to prote

214 ensemble and reveal that ultrafast (~50 fs) modulation of the exciton frequencies governs spectral b

215 Modulation of the fidelity of translation initiation by

216 egulatory function and significant impact on modulation of the host immune response.

217 sembled capsule, a kinetic and thermodynamic modulation of the imine constituents of the DCLs was obs

218 from extracellular matrix reorganization to modulation of the immune response and Rho signaling.

219 Strong resonant modulation of the incident electromagnetic field is achi

220 The extent of the modulation of the individual firing of hippocampal neuro

221 immunoprophylaxis efficacy at baseline, and modulation of the KEL glycoprotein antigen occurred to t

222 Thus, we show that a location-dependent modulation of the mechanical properties of cells leads t

223 Moreover, artificial modulation of the membrane curvature near integrin alpha

224 nable non-invasive, spatiotemporally precise modulation of the microtubule cytoskeleton in living cel

225 ants responsible for its positive allosteric modulation of the receptor, are unknown.

226 Thus, the betaAR-mediated modulation of the release machinery and the subsequent i

227 Yet, initial burst release and optimal modulation of the release profiles limit their clinical

228 The study describes modulation of the rho1 GABA(A) receptor by neurosteroids

229 nstream of P1 neurons to mediate nutritional modulation of the sleep-courtship balance.

230 kin conductance responses or pupil dilation, modulation of the startle reflex is valence specific.

231 ythmic bursts of information, resulting in a modulation of the stimulus content within the receiving

232 hat limit NK cell functions, and therapeutic modulation of the TME to enhance antitumor NK cell funct

233 ols systemic L. monocytogenes spread through modulation of the type I IFN response, which is known to

234 Modulation of their activity offers therapeutic opportun

235 atures, and we report notable fever-mediated modulation of their cytokine commitment.

236 when infected with biofilm-grown cells, and modulation of their regulation is sufficient to cause th

237 ticles into biomedical applications requires modulation of their surface properties so that the inter

238 e response to vascular stress and phenotypic modulation of this cell type in coronary artery disease

239 Modulation of this circuit induced social deficits and r

240 s, and how they respond to each other in the modulation of this complex plant defense response.

241 s effect on systemic growth results from the modulation of Tor signalling and lysosomal homeostasis w

242 phorylation of H2AX and CHK1, suggesting the modulation of transcription and DNA damage that may be m

243 Cu(2+)-dependent modulation of transretinal signaling only occurs in the

244 target in cancer and implicate GSTO1 in the modulation of tumor growth, immune responses, and expres

245 findings demonstrating significant, dynamic modulation of tumor hypoxia with the heme-targeting drug

246 cancer cell stemness to miR-486-5p-dependent modulation of tumor suppressor genes that feeds back to

247 have been proposed as a hub for attentional modulation of underlying cortex, but the transformations

248 Modulation of vascular endothelial growth factor-mediate

249 at this mechanism plays an important role in modulation of vascular function and BP in experimental m

250 of vesicle circularity, lobe formation, and modulation of vesicle compactness.

251 provide insights into the dynamic and unique modulation of vimentin, depending on the stage of human

252 ted into the nucleus for its function in the modulation of viral mRNA processing and viral DNA replic

253 athways interact to contribute to contextual modulation of visual cortical processing.

254 ate and, more generally, the pharmacological modulation of whole-brain activity.

255 nd breast cancer pathogenesis likely via the modulation of Wnt/beta-catenin signaling pathway, a key

256 ndings revealed associations with epigenetic modulations of genes regulating neurotransmission, neuro

257 Voluntary movement initiation involves the modulations of large groups of neurons in the primary mo

258 Modulations of oscillations in the alpha to beta range i

259 Here we show that modulations of surprise and uncertainty are encoded in a

260 infections affect TE transcript amounts via modulations of the piRNA and siRNA repertoires, with the

261 anti-nociceptive effects of sinusoidal rate modulation on EEG outlasted SCS duration on the behavior

262 t studies have revealed significant cultural modulations on face scanning strategies, thereby challen

263 for the potential contributions of feedback modulations on size representations in EVC, we investiga

264 ression of inhibition (DSI) and CB1 receptor modulation only at IT cells.

265 membrane potential, and proteasome activity modulation, only Diclofenac exposure shows a marked alte

266 ttention has been given to their therapeutic modulation or roles in vaccination in these diseases.

267 rformance, as measured using pulse amplitude modulation (PAM) fluorometry, showed that the optimized

268 gorithms to generate two different intensity-modulation patterns, namely to form a downslope and a fl

269 echanism elucidates distinct tissue-specific modulations, pharmacology, and disease pathogenesis of K

270 dgap modulation up to ~300 meV and a highest modulation rate of ~136 meV/%, which is approximate two

271 nhibit cardiomyocyte cytokinesis through ECM modulation rather than by secreting diffusible factors.

272 Cognitively driven pupil modulations reflect certain underlying brain functions.

273 One hypothesis is that P300 modulations reflect the degree of "surprise" associated

274 e aspirin (ASA) have been proposed as a host modulation regimen to control chronic inflammatory disea

275 hanistic understanding of TRPC6 function and modulation remains obscure.

276 to assess the effectiveness of sacral nerve modulation (SNM) in a large cohort of patients implanted

277 The roles of dopaminergic neurons in the modulation, structuring and execution of behavioral elem

278 how control of localized dose deposition and modulation, suitable to target a volume at depths in the

279 mpanied by activation of the endogenous pain modulation system, manifested by the attentional modulat

280 ere better accounted for by a DDM with value modulation than by a null model without value modulation

281 of the IPP markers demonstrated various gene modulations that could distinctly differentiate 3 profil

282 re of GS topography by showing its rest-task modulation, the underlying dynamic coactivation patterns

283 t roles in bacterial virulence and in immune modulation through the transmission of biologic signals

284 ations may represent a mechanism of synaptic modulation throughout the CNS.

285 t link phenomenological observations of gain modulation to underlying cellular and circuit-level mech

286 onolayer MoS(2), we observe a higher bandgap modulation up to ~300 meV and a highest modulation rate

287 erential infrared pyrometer based on spatial modulation using a resonant oscillating mirror, which en

288 probed the spatio-temporal dynamics of eCRF modulation using a reverse correlation paradigm, and fou

289 ically introduced by efficient electro-optic modulation via a sum-frequency-generation process in hig

290 the antidepressant actions of NMDAR-positive modulation vs. NMDAR blockade.

291 d NOTCH receptor engagement, gamma-secretase modulation was rationalized as a therapeutic option.

292 This value modulation was related to the strength of participants'

293 Task-dependent neural modulations were similar in both regions.

294 progress to high-grade disease after immune modulation, which can be effectively managed with crosso

295 l NMJ targets and pathways whose therapeutic modulation will help slow the progression of motor neuro

296 This allows us to obtain optical modulation with the low, millivolt-level signal generate

297 ) (where E is the energy) reveals electronic modulations with wavevectors Q and 2Q, as anticipated wh

298 l isolator is demonstrated by spatiotemporal modulation, with over 17 dB isolation achieved.

299 The extent of alpha power modulations within participants was negatively correlate

300 he paper further suggested that this form of modulation would play a role in setting the spinal inhib