ライフサイエンスコーパス: module

1 isruption of the MutS homologue 2 (MSH2)-ATR module.

2 insically stretchable organic thermoelectric module.

3 that light uncages the G-protein activating module.

4 a switchable polarization selective grating module.

5 kinson's disease within the substantia nigra module.

6 lation machinery (TM), an essential cellular module.

7 c relevance of the "extended" model of a PKS module.

8 n SECs with eNOS in a GIT1/eNOS/NO signaling module.

9 between these two subunits of the MED middle module.

10 , resulting in creation of a coupled TTD-PHD module.

11 inant variant shuffles independently in each module.

12 lify as targets of this DELLA-GRF regulatory module.

13 overlapping sub-clusters using the GOMCL-sub module.

14 turn enhances the function of the synthetic module.

15 e Tra1 module, whereas Sgf73 tethers the DUB module.

16 esis to gene expression with the STOP1-ALMT1 module.

17 y at night using a commercial thermoelectric module.

18 ature signaling by fine-tuning the phyB-PIF4 module.

19 activation of confined downstream signaling modules.

20 ssociated with discrete microglia activation modules.

21 etic constraints, conforming to evolutionary modules.

22 hips through five user-friendly, interactive modules.

23 DeepRiPP includes 3 modules.

24 it the power of natural selection to improve modules.

25 ic regulation in NSDs, miRNA modules and NSD modules.

26 nsferase fold and three carbohydrate-binding modules.

27 ranscription factors regulating co-expressed modules.

28 , peripheral stalk (PS), and c(8)-rotor ring modules.

29 y close-packed (TCP) and Mackay cluster-like modules.

30 XP3/IL2-with inflammation-and Th2-associated modules.

31 iver genes that regulate these co-expression modules.

32 d 14-16 subunit complex composed of discrete modules.

33 -SANT associated (HSA) domain connecting all modules.

34 nformation, primarily from the matrix to the modules.

35 a web portal with specialized visualization modules.

36 velopment and imaging characteristics of the modules.

37 one is encoded by different transcriptional modules.

38 rality in the peripheral blood and placental modules.

39 d non-acquired focal epilepsy formed disease modules.

40 affinity to the ketoreductase domain of DEBS module 1 (KR1).

41 bstinence network revealed three major brain modules: 1) extended amygdala module, 2) midbrain striat

42 ee major brain modules: 1) extended amygdala module, 2) midbrain striatal module, and 3) cortico-hipp

43 arallel-connected stack SMFCs similar to the module-5.

44 igand similarity analysis suggests that only module 6R may be compatible with strainless monofunction

45 hieved by stringing together its controlling modules (A-domain and loop Nbeta5-beta6) with catalytic

46 In addition to the HY5/PIF-dependent shoot module, a regulatory axis composed of auxin biosynthesis

47 of manual synthesis and automated synthesis modules, a sterile cold kit was recently introduced.

48 CPSF contains two functionally distinct modules: a cleavage factor (mCF) and a polyadenylation s

49 Our webserver consists of three modules: (a) RAG Sampler: samples tree graph topologies

50 By comparison, the 4-to-1 coupled Prism-PET module achieved a DOI resolution of 2.5 mm FWHM and an e

51 strate deep conservation of a nucleolus gene module across very divergent organisms, and in the secon

52 l neuronal subtypes that stably express gene modules across all intestinal segments, with graded, reg

53 s how cytoprotective and cytotoxic signaling modules activated by radiation in specific cell populati

54 When inserted side-by-side, these modules advance replication timing over a 250 kb region

55 We analysed the dynamics of these two modules alone and in mixed scenarios.

56 base of the photoreceptor OS where the PCARE module and actin colocalize, but which is abrogated in P

57 combination of optical data from the camera module and chemical data obtained by mass analysis facil

58 D are enriched in a microglial AD-associated module and identify key transcription factors regulating

59 cuits in the inferior colliculus connect the module and matrix regions, providing an avenue for integ

60 er, many motile cells rely on both signaling modules and actin cytoskeleton to break symmetry and ach

61 Recurrent gene modules and cell types are affected across this cohort o

62 Net as a tool for identifying conserved gene modules and comparing co-expression networks.

63 es in which synchronization of relevant gene modules and concurrent repression of competing fate prog

64 he assembled transcripts, reconstructed GRN, modules and detailed annotations are all available as Su

65 data can provide insights via co-expression modules and hubs, alternative forms of computational mod

66 regulate multiple cell fate related function modules and interact tightly based on their functional s

67 miRNA synergistic regulation in NSDs, miRNA modules and NSD modules.

68 informs the biological properties of disease modules and presents a model for secondary-variant burde

69 eptibility to infection), using our software modules and publicly-available software repository.

70 ecies through a greater enlargement of shoot modules and quicker secondary branching of roots.

71 tended amygdala module, 2) midbrain striatal module, and 3) cortico-hippocampo-thalamic module, remin

72 ng, upregulated an IRF8-dependent maturation module, and acquired antigens via convalescent serum and

73 form glass light-guide, one 4-to-1 Prism-PET module, and one 9-to-1 Prism-PET module) to introduce in

74 ophrenia within the putamen and white matter modules, and a significant enrichment of the heritabilit

75 amer-like fold, flexibly links the enzymatic modules, and facilitates TBP loading onto TATA promoters

76 ennas, printed energy harvesting and storage modules, and printed displays, are discussed.

77 recently-discovered mechanisms of the Dorsal module are critical for robustness.

78 The accuracy and feasibility of the module are verified by three typical cases.

79 l distributions, suggesting different output modules are controlled by distinct inhibitory circuit mo

80 mical motifs with distinct inputs: GABA-rich modules are innervated by somatosensory structures, whil

81 impaired angiogenesis, suggesting that these modules are instrumental to the temporal coordination of

82 riants with just three alternating active D2 modules are robust protein translocases and function wit

83 ion for flexibly switching between task rule modules, as is useful, for example, when multiple stimul

84 These receptor modules associate with three signaling modules (CD3gamma

85 A lipogenesis gene module associated with weight loss was evaluated by test

86 atasets, to identify gene network regulatory modules associated with GBM.

87 disproportionately cluster within regulatory modules associated with heat tolerance.

88 g a role of SPAs in regulating the phyB-PIF4 module at high ambient temperature.

89 In this work we analyze module-based network approaches to build gene regulatory

90 a paradigm shift compared with more typical module-based or classroom ethics instruction that is div

91 We created a series of hybrid PKS modules bearing exchanged TE domains from heterologous p

92 mation with native substrates and hybrid PKS modules bearing non-cognate TE domains was severely redu

93 e X-ray scattering (SEC-SAXS) of this hybrid module bound to 1D10 provided further support for the ca

94 ced by a model featuring the CatSper and NHE module but not by those including the pH-independent CaV

95 complex is bound to the preformed F(1)-c(8) module by subunits OSCP and F(6) The final component of

96 frequency to flexibly bind appropriate task modules by synchrony.

97 In the first module, [Ca2+]i-spike trains require the concerted actio

98 olytic processing of PGRN to smaller protein modules called granulins (GRNs) contributes to FTLD and

99 p reactions or in multistep processes, where modules can be connected to each other in reconfigurable

100 These redefined modules can be used for single-step reactions or in mult

101 Implantation of multiple modules can cover extended brain regions.

102 tion of feasible manufacturing and renewable modules can offer an attractive advancement to this fiel

103 seq data, we showed that the core regulatory modules can reflect the properties of different subpopul

104 domains and one or more carbohydrate-binding modules (CBMs).

105 eptor modules associate with three signaling modules (CD3gammaepsilon, deltaepsilon, and zetazeta) an

106 The Cdk8 kinase module (CKM) is a detachable Mediator subunit composed o

107 ulization analysis, wherein we identified 25 modules; ClueGo plug-in was used for the pathway's enric

108 RAD uses gene module compression to mitigate considerable noise in RNA

109 SD-gene repression validated this functional module, confirming that these genes reduce neural progen

110 The core module consists of subunits Taf5, Sgf73 and Spt20, and a

111 This module contained many genes involved in synaptic signali

112 ized at the tips by a cytoplasmic tripartite module containing the scaffolds USH1C and ANKS4B and the

113 T2alpha and pro-inflammatory transcriptional modules, contributing to CNS pathology in EAE and, poten

114 g this molecule with a bleomycin A5 cleaving module converts the simple binding compound into a poten

115 We hypothesize that modules could be discovered within the autoencoder repre

116 eveloped an automated and fast fractionation module coupled online to MS.

117 nding sites based on inferred cis-regulatory modules (CRMs).

118 The Spectrum AIDS Impact Module developed by Avenir Health, UNAIDS, and partners

119 nts with lung cancer and was the first EORTC module developed for use in international clinical trial

120 served features of two chromosome metabolism modules, DNA replication and sister chromatid cohesion,

121 In addition, this fast module does not control wound-triggered JA accumulation

122 A neighboring X-module domain allosterically regulates the binding inter

123 olo tightly regulates the RZZ-Spindly-dynein module during mitosis to ensure the fidelity of chromoso

124 azeta) and work in concert with a coreceptor module (either CD8 or CD4) to drive T cell activation in

125 connections reveals three recurrent circuit modules engaged sequentially to increase locomotor speed

126 JNJ-55511118, and JNJ-61432059) as the major module engaging gamma8 by an H-bond to Asn-172 (gamma8).

127 Among them, Magnets are small modules engineered from the Neurospora crassa photorecep

128 d a dopamine D2 receptor (DRD2) coexpression module enriched for SCZ risk genes and associated with c

129 The design of the LightR module ensures broad applicability of the tool, as we de

130 We propose that the EPFL2 signaling module evolved to control the initiation and regular, eq

131 Therefore, each output module exhibits a unique position within the claustrum a

132 Two candidate modules featuring voltage-dependent Ca2+-channels link t

133 with a rigid citrate synthase homology (CSH) module, flanked by four flexible acetyl-CoA synthetase h

134 In this work, we present a fully 3D-printed module for attenuated total reflection Fourier transform

135 e whose main novelties include an innovative module for cell detection based on multiscale directiona

136 -PIF3-phyB serves as an important regulatory module for modulating plant response to cold stress.

137 uggest that this is a functional replication module for SCCmec.

138 In particular, this version incorporates a module for structural discovery of complete long termina

139 o biocatalytic DNA machineries as functional modules for the emergence of CDNs of diverse composition

140 MutEnricher contains two distinct modules for these purposes that provide customizable opt

141 Forty-nine gene signatures (modules) for differentially stimulated macrophages, one

142 e PCNA opening, with the clamp loader ATPase modules forming an overtwisted spiral that is incapable

143 t DHS standard) and a full pregnancy history module (FPH), which collects information on all livebirt

144 e-specific and evolutionarily conserved gene modules from both neuronal and glial cell classes.

145 he optical consequences of the soiling of PV modules from the particle size distribution and the clea

146 overlapped significantly with endophenotype modules governing inflammation, thrombosis, and fibrosis

147 In trophic networks, "modules"-groups of species that interact more with each

148 Both modules harbor a reservoir of latent dynamics, and their

149 A hybrid PKS module harboring KR1 was engineered, whose individual ca

150 Although the components of this signaling module have been characterized in detail, how their func

151 A synthetic biological module, however, can be designed to reprogram the host p

152 To this end, we launched the 'Disease Module Identification (DMI) DREAM Challenge', a communit

153 t of functionally related metabolic reaction modules identified within the model via flux coupling an

154 mprised of the bipartite zona pellucida (ZP) module in a helical arrangement with a rise of ~65 angst

155 a role for this new JBTS-associated protein module in ciliary stability.

156 f homologous gene variants co-exist for each module in each location, however, the dominant variant s

157 teins represent a highly conserved signaling module in eukaryotes that regulates diverse cellular pro

158 tablish the conserved importance of the CDK8 module in plants and provide evidence for the function o

159 ic expression of a plant bipartite signaling module in plants has not been shown previously and, by e

160 ines the essential roles of a RhoGEF-anillin module in septin architectural remodeling during cytokin

161 The application areas for electronic modules in chemistry research include construction of si

162 owever, there is no requirement for adjacent modules in either ring to be active for efficient enzyme

163 tural visualization and redirection to other modules in GlycanStructure.ORG for further investigation

164 Disease modules in molecular interaction maps have been useful f

165 Novel modules in the primary sequence of alpha-synuclein optim

166 Here, We investigate the impact of module inclination on system-level flow and the convecti

167 The SSc disease module includes the emerging molecular targets and is in

168 rks involved multiple discrete co-expression modules including those related to Th2-, type1 IFN-, inf

169 ghting 78 differentially enriched functional modules including tryptophan biosynthesis function.

170 rnative pathways operate to introduce the PS module (including associated membrane subunits e, f, and

171 We used co-expression modules inferred from gene expression data with five met

172 Binding of GIV's TILL motif to TIR modules inhibits proinflammatory signaling via other TLR

173 ht-emitting diode (LED)-induced fluorescence module integrated into the device.

174 Integrating these computational modules into a pipeline (ProNorM), we mitigate variation

175 ves the design and construction of different modules into a rationally integrated system that mimics

176 kingdom relationship of cell death execution modules involved in organismal defense.

177 However, expression of gene modules involved in triglyceride (TG) synthesis and adip

178 At its core, a flow chemistry module is a stable set of conditions - traditionally tho

179 The module is bifurcated by the alpha2 helix dividing two di

180 ion of two B-family Pols; the N-terminal Pol module is catalytic and the C-terminal Pol module is non

181 e find that this novel RBM24-Sox2 regulatory module is essential for early eye development in vertebr

182 l module is catalytic and the C-terminal Pol module is non-catalytic.

183 The TBC1D4-RAB10 signaling module is required for insulin-stimulated GLUT4 transloc

184 The PLT-CUC2 module is required for vascular regeneration, but is dis

185 modules of the GRN and hypothesize that one module is responsible for translating the extracellular

186 Surprisingly, the ARP module is rotated 120 degrees relative to the full RSC a

187 e structure, the actin-related protein (Arp) module is sandwiched between the ATPase and the rest of

188 0-14), but the structure of the central core module is unknown.

189 The evolution of semi-independent modules is hypothesized to underlie the functional diver

190 dules, TPOT-FSS corroborates that one of the modules is largely predictive of the clinical diagnosis

191 lene signaling in which the KAR/KL signaling module (KAI2-MAX2-SMAX1) regulates the biosynthesis of e

192 sh between iterative and noniterative at the module level remains an overwhelming challenge, which ma

193 is based on an intuitive concept of stacking modules, like conventional toy interlocking plastic bloc

194 A protein network module linked to sugar metabolism emerged as one of the

195 The study reveals a transacting protein module LRPPRC-SLIRP that delivers mt-mRNA to the mitorib

196 built of three putative carbohydrate-binding modules (M1, M2 and LysM3).

197 type (GABAergic/non-GABAergic) and location (module/matrix).

198 ngle highly integrated co-expression network module, maximizing potential for stable homeostatic cont

199 We surmise that mature locomotor modules may derive by combining the multiple patterns of

200 rinsic planar polarity (referred to as iPCP) modules mediate planar polarization of the hair cell api

201 we investigated the contribution of the MAPK module MEK5-ERK5 to SCLC growth.

202 e-gene coexpression, captured by subnetwork (module) membership.

203 ed to sugar metabolism emerged as one of the modules most significantly associated with AD pathology

204 Coupled with an efficient desolvating module, N(2)O was used as the reaction gas in the collis

205 In the disease-module network, the greatest perturbing activity was sho

206 Description of HMM module-obtained macula images.

207 at a conserved bromo-adjacent homology (BAH) module of BAHCC1 (BAHCC1(BAH)) 'recognizes' H3K27me3 spe

208 Here, we report that the NADH-oxidizing N-module of CI is turned over at a higher rate and largely

209 n of the PHY domain of a 57-kDa photosensory module of Deinococcus radiodurans phytochrome changes fr

210 -dimensional (3D) structure of the catalytic module of human CAK, revealing the structural basis of i

211 who harbor pathogenic variants in the ATPase module of MORC2.

212 demonstrate that two copies of the catalytic module of poly(A) polymerase (PAP) are recruited by the

213 IN C1 (CYCC1), components of the CDK8 kinase module of the Mediator complex, which is a deeply conser

214 eration but low competition reveals distinct modules of bacterial interactions.

215 elation network analysis (WGCNA) to identify modules of co-expressed genes.

216 o classify the synthetic community into four modules of co-occurring strains.

217 cells at age 6 years, 792 of which formed 3 modules of correlated differentially methylated CpGs.

218 n-coding mutations that cluster into several modules of interacting proteins.

219 he Dpb3-Dpb4 subunits bridge the two DNA Pol modules of Pol2, holding them rigid.

220 internal and external validation procedures, modules of selected interest were tested for enrichment

221 We found that the neuromuscular modules of stepping and kicking differ substantially.

222 We characterized two biomineralization modules of the GRN and hypothesize that one module is re

223 genes belonging to the different functional modules of the network revealed that 76% of the genes an

224 tes that the chromatin-binding and enzymatic modules of UHRF1 do not act in isolation but interplay i

225 aving expansion strategy for functional gene modules optimization using information divergency and (i

226 hose including the pH-independent CaV and BK module or proportionate mixed scenarios.

227 the nacreous shell layer, whereas the second module orchestrates the transport of both ions and prote

228 The Upstream module outputs were fitted to kinetic data on cGMP activ

229 revealed that 76% of the genes and all gene modules participate partially in RKS1-mediated resistanc

230 The Patient Health Questionnaire depression module (PHQ-9) is a 9-item self-administered instrument

231 ally, these functionally convergent ASD gene modules predicted shared clinical phenotypes among indiv

232 tic use in glaucoma patients of the Glaucoma Module Premium Edition (GMPE) available for the Spectral

233 Finally, targeted lesioning of modules produced deficits similar to those observed in l

234 ustrum and overlaps substantially with other modules projecting to functionally related cortical regi

235 Assessing if this PKCepsilon-Aurora B module provides a more widely exploited genome-protectiv

236 uality of life Questionnaires, Breast cancer module [QLQ-BR23] and Fatigue module [QLQ-FA12], Hospita

237 Breast cancer module [QLQ-BR23] and Fatigue module [QLQ-FA12], Hospital Anxiety and Depression Scale

238 metric properties of the updated lung cancer module, QLQ-LC29, in patients with lung cancer.

239 by preventing the incorporation of the NADH module rather than decreasing its stability.

240 that SWIM analysis can identify key network modules related to complex diseases like COPD.

241 ssium channel, BK (Slo1), whereas the second module relies on pHi-dependent CatSper dynamics articula

242 l module, and 3) cortico-hippocampo-thalamic module, reminiscent of the three-stage theory.

243 We implement a self-coalescence module (SCM) for the controlled reconstitution and deliv

244 (WGCNA) and c1_HuAgeGBsplit_32/193 (MEGENA) modules showed significant enrichment of rodent quiescen

245 d coexpressed in the normative transcriptome module specialized for innate immune and neutrophil func

246 atics based on these initial conditions in a module-specific way.

247 al CI arising from the inactivation of the N-module subunits due to attrition caused by its constant

248 photovoltaic energy, new approaches to limit module temperature increase in natural ambient condition

249 development in Arabidopsis A shoot signaling module that includes HY5, the phytochromes and the PIFs

250 ng the existence of an NHR-23/NR1F1-mediated module that regulates the spermatogenesis program.

251 We thus identify a potential regulatory module that takes advantage of the redundancy in the gen

252 3D architectures for implantable probe-array modules that are designed to provide fast and dense sing

253 eam of target genes, defining cis-regulatory modules that are enriched for DNA sequence motifs that r

254 itory-recipient matrix regions and GABA-rich modules that are innervated by somatosensory inputs.

255 MemorySeq revealed multiple gene modules that expressed together in rare cells within oth

256 ns are organized into putative computational modules that reflect the known functional domains of the

257 owered within each to discover gene response modules that vary by time and cell subset.

258 network analysis revealed DNA comethylation modules that were associated with clinical traits includ

259 s implemented to identify microRNA networks (modules) that significantly correlate with clinical feat

260 QOL was assessed using the EORTC QLQ-OG25 module, the SF12v2 score, and the hospital anxiety and d

261 hylation antagonizes an active transcription module, thus reducing H3K36me3 accumulation and increasi

262 eploys a cytoplasmic kinase-endoribonuclease module to activate the transcription factor XBP1s, which

263 route involves the addition of the c(8)-ring module to the complete F(1)-PS complex.

264 We fitted the Cenp-HIKHead-TW sub-module to the previously determined cryo-EM map of the S

265 en expressed ectopically, act as a bipartite module to trigger a self-recognition:self-destruct respo

266 We use these modules to assemble a cell-free biocircuit that can comb

267 ctive introduces nucleic acids as functional modules to construct constitutional dynamic networks, CD

268 1 Prism-PET module, and one 9-to-1 Prism-PET module) to introduce intercrystal light sharing, which c

269 ory network motif, the negative single-input module, to explore the regulatory properties inherited f

270 association with depression severity of two modules, TPOT-FSS corroborates that one of the modules i

271 otentially form a transcriptional regulatory module (TRM) (e.g. co-binding TFs), which helps decipher

272 h a system of acquisition of diverse protein modules, typically in inactive form, from various cellul

273 ng these data to identify active pathways or modules under certain experimental conditions or phenoty

274 n circulation were organized into regulatory modules under genetic control and closely associated wit

275 The endonuclease and the entire cleavage module undergo extensive rearrangements for activation,

276 mercury cadmium telluride balanced detection module was employed.

277 This module was enriched in AD genetic risk factors and in mi

278 Within molecularly defined cerebellar modules we found spatial overlap of mossy fiber terminal

279 To validate the identified modules, we also performed literature validation as well

280 The ES for most modules were also significantly reduced in severe asthma

281 .Measurements and Main Results: Six microRNA modules were associated with clinical features of asthma

282 The identified modules were derived from the substantia nigra, putamen,

283 Methods: High-resolution PET detector modules were fabricated with single-ended readout of pol

284 Four significantly interconnected protein modules were found among the high-priority ADHD genes.

285 sity by possession of numerous flexible gene modules, where homologous genes present in the pan-genom

286 Spt20 form flexible connections to the Tra1 module, whereas Sgf73 tethers the DUB module.

287 We created an interactive web module which allows for quick geographic visualization o

288 Moreover, we develop a GIS-based extension module which combines the grid-based data with the 3D sl

289 Cells consist of molecular modules which perform vital biological functions.

290 yeast 2-hybrid screens to identify a ciliary module whose dysfunction underlies JBTS.

291 nonreadout side to a light-guide (one 4-to-1 module with a uniform glass light-guide, one 4-to-1 Pris

292 are two questionnaires: a full birth history module with additional questions on pregnancy losses (FB

293 robustness of the Dorsal/NF-kappaB signaling module with respect to perturbations to the dosage of ma

294 veal that RALF4 binds LLGs and LRX cell-wall modules with drastically different binding affinities, a

295 expression network analysis detected 4 and 7 modules with genes highly associated (r > 0.50, p < 0.05

296 Reactions pairing wildtype PKS modules with non-native substrates primarily resulted in

297 ng an annotated gene and highlight metabolic modules with poorly correlated gene fitness scores.

298 pattern, with 61% of contigs clustering into modules with statistically significant diel periodicity.

299 reusing only 22 distinct steps in 10 unique modules, with the code able to access 17 different react

300 n this work, we dissect the contributions of modules within the disordered CTT to assembly and enzyma