ライフサイエンスコーパス: molecular event

1 MR signal change can serve as a read-out for molecular events.

2 , temporally coordinates an array of complex molecular events.

3 integrated system that mimics the cascade of molecular events.

4 hus important to understand underlying early molecular events.

5 re often insufficient in examining transient molecular events.

6 d systems-level properties to the underlying molecular events.

7 nomic profiles and can be driven by distinct molecular events.

8 ne transcription through a series of defined molecular events.

9 involving physiological, physiochemical, and molecular events.

10 facts and precludes determining the order of molecular events.

11 ss state of a cell comprise a diverse set of molecular events.

12 rs (TFs) and trigger a cascade of downstream molecular events.

13 factors makes it difficult to dissect these molecular events.

14 a novel genetic interaction between these 2 molecular events.

15 Inspired by these molecular events, a reconstructed ivy-mimetic adhesive c

16 t anti-androgen therapies however, the exact molecular events accompanying NE transdifferentiation an

17 udies define the metabolic, biochemical, and molecular events accompanyingHCCevolution, regression, a

18 ar that trisomy 21 causes Down syndrome, the molecular events acting downstream of the trisomy remain

19 tin accessibility and mediating a cascade of molecular events affecting pluripotency.

20 the visual dark adaptation, the fundamental molecular event after photobleaching of rhodopsin is the

21 Elucidating the precise molecular events altered by disease-causing genetic vari

22 This argued strongly in favor of an isolated molecular event and against a common lymphoid CD19(-) pr

23 etween these thyroid hormone (TH) disrupting molecular events and adverse outcomes relevant to aquati

24 mation requires the temporal coordination of molecular events and cellular processes following a lear

25 s critical for understanding the dynamics of molecular events and electric currents that shape physio

26 To better understand the molecular events and explore new pathways responsible fo

27 However, further investigations on molecular events and pathways responsible for developmen

28 nsional tumor biomarker data to identify key molecular events and pathways that are central to an und

29 a more detailed understanding of pathologic molecular events and to identify biomarkers that may hav

30 intimately affect various cell responses and molecular events; and this range of mutually reinforcing

31 Finally, we confirm that the same key molecular events are also seen in human radiation dermat

32 Reconfigurable molecular events are key to molecular machines.

33 t transposon transcripts, yet the subsequent molecular events are not understood.

34 We found that these molecular events are strongly influenced by p53's engage

35 However, the defining molecular events are unknown.

36 precisely follow and measure subcellular and molecular events, are paving the way for a more complete

37 by sensory proteins constitute the critical molecular events as living organisms respond to changes

38 The mutant JAK2 V617F is the most common molecular event associated with myeloproliferative neopl

39 ted opportunities to understand the earliest molecular events associated with carcinogenesis, enablin

40 arious reproductive tissues and captured the molecular events associated with distinct reproductive p

41 Here, we studied early molecular events associated with host recognition in Fus

42 To identify molecular events associated with HPV16 carcinogenesis, w

43 hanges in regulatory sequences, but specific molecular events associated with major morphological tra

44 We also biochemically characterized the molecular events associated with refolding of the metast

45 mical and imaging approach, we dissected the molecular events associated with the different stages of

46 The molecular events associated with the protective effect o

47 d with its pathogenesis, we investigated the molecular events associated with the termination of IL-1

48 Characterizing these functionally important molecular events at a microscopic level is key to our un

49 ction, a bottom-up approach was used to link molecular events at the single-cell level into the event

50 upport a mechanistic link to the genetic and molecular events behind PAH pathogenesis.

51 he mTORC1 cascade activation as an important molecular event by which D2R mediates its effects.

52 The molecular events by which each otoferlin C2 domain contr

53 ha-synuclein-rich deposits suggestive of one molecular event causing distinct disease phenotypes.

54 we discuss our current understanding of the molecular events controlling cellular metabolism downstr

55 g pathogen weaknesses; yet, the hierarchy of molecular events controlling fungal responses to the pla

56 Understanding the molecular events controlling melanoma progression is of

57 dent niche precursor fate and the transitory molecular events controlling niche formation and functio

58 Understanding the molecular events controlling this production will be cri

59 on of signal bias is an understanding of the molecular events coupling ligand binding to intracellula

60 hat can also generate hypotheses on specific molecular events disrupted by the variant.

61 It remains unclear, however, whether the molecular events downstream of cGMP involve BK channels

62 highlight yet unidentified insights into the molecular events driving cancer evasive resistance and s

63 The identity of the cells and molecular events driving deleterious calcification of he

64 their control, and thus uncover the specific molecular events driving disease risk.

65 buting to proliferative immortality, but the molecular events driving TERT activation are largely unk

66 for other MFS members, the key residues and molecular events driving transport by Pi:H(+) symporters

67 type cancers are deadly malignancies but the molecular events driving tumor lethality are not complet

68 and phosphorylated at threonine 206-an early molecular event during membrane fusion.

69 t the coding region of ClVST1(97) as a major molecular event during watermelon domestication, which r

70 nsors toward subcellular FAs to report local molecular events during cancer cell adhesion.

71 ches, but the precise timing and sequence of molecular events during embryonic development are largel

72 Early molecular events during reprogramming involved the activ

73 Molecular events during storage may influence the severi

74 propose the use of drugs to inhibit specific molecular events during the aggregation process.

75 y has played a key role in understanding the molecular events during the transport processes and thei

76 ge, indicating rapid progression of specific molecular events during this period.

77 ly assigned in the classical pathway view of molecular events (e.g. signal transduction).

78 A series of cellular and molecular events following biomaterial implantation pose

79 t not following PTC sets in motion cascading molecular events for the acquisition (AMPARs) and subseq

80 amatically enhanced our understanding of the molecular events governing clonal evolution in MPNs, the

81 s challenging, therefore strategies to study molecular events governing progression of pre-invasive T

82 PSDs is considered as one of the most basic molecular events governing synaptic plasticity in the ne

83 lar complications; however, the cellular and molecular events governing vascular malformations are no

84 Investigating the temporal behavior of molecular events has been an important subject to unders

85 learned helplessness paradigm and regulates molecular events implicated in the mechanism of action o

86 GRM3 expression is a functionally important molecular event in colon cancer, and that GRM3 is a prom

87 onic increase in Ca(2+) influx is a critical molecular event in homeostatic downscaling of glutamater

88 ed conversion (RT-QuIC) to model the central molecular event in prion disease, the templated misfoldi

89 disease-causing isoform (PrP(Sc)) is the key molecular event in the formation of PrP(Sc) aggregates.

90 ML) is that it results from a combination of molecular events in a hematopoietic stem cell that block

91 emarkable progress was made in understanding molecular events in allergies as a prerequisite for effe

92 s with long-term aspirin use, the changes of molecular events in AM but not IM may be an important fa

93 Visualization of dynamic functional and molecular events in an unperturbed in vivo environment i

94 Key molecular events in atherogenesis such as oxidative modi

95 We studied early molecular events in axonal degeneration with single-axon

96 Here I discuss the regulation and molecular events in cancer that are associated with thes

97 l over the combination, order, and timing of molecular events in cells.

98 ltrasensitive detection and rapid mapping of molecular events in chemical and biomedical systems.

99 rearrangements, which may involve different molecular events in different cells, contribute to a sel

100 hnologies provide useful approaches to study molecular events in different signalling pathways, produ

101 e evaluated whether ketamine elicits similar molecular events in dopaminergic (DA) neurons, known to

102 eral novel insights for our understanding of molecular events in EAC.

103 jections to the characterization of specific molecular events in each SPN subtype and their impact on

104 OTC platform to characterize the underlying molecular events in esophagitis.

105 To further delineate the early molecular events in HD, we performed RNA-sequencing (RNA

106 Molecular events in IDH WT GBMs were stable in approxima

107 ly versatile means for sensitive analysis of molecular events in living organisms.

108 Knowledge of the molecular events in mitochondrial DNA (mtDNA) replicatio

109 first report to our knowledge on the initial molecular events in MSC exosome mediated cytoprotection

110 s into macrophages are critical cellular and molecular events in NEC development to promote disease.

111 The molecular events in response to severe hyperthermia are

112 ed this interaction to identify cellular and molecular events in response to this oomycete, which has

113 should be conceived in terms of cellular and molecular events in specific circuits rather than in ter

114 able to identify a number of potentially key molecular events in the advance of breast cancer to mali

115 f-concept for a non-invasive assay of global molecular events in the cytoplasm of living animals.

116 To decipher CNTF-triggered molecular events in the degenerating retina, we performe

117 The molecular events in the iron-C3 pathway represent therap

118 Investigating the detailed molecular events in the Ras-PI3K interaction has been ch

119 To comprehensively characterize the molecular events in this dynamic process, we set to dete

120 The ability to record molecular events in vivo would enable monitoring of sign

121 simultaneously explore multiple physiologic/molecular events in vivo.

122 tal carcinoma evolves through a multitude of molecular events including somatic mutations, epigenetic

123 t, and immunosuppression driven by different molecular events, including somatic copy number aberrati

124 nderstood, but less is known about how these molecular events influence microbial dynamics on the pop

125 Our studies thus identified critical molecular events initiated by mechanical forces and pote

126 Comparison of the molecular events initiated by small interfering RNA for

127 amycin system have been widely used to probe molecular events inside and outside cells.

128 ility to write a stable record of identified molecular events into a specific genomic locus would ena

129 However, many questions remain as to the molecular events involved in CCP initiation, stabilizati

130 the past decades, very little is known about molecular events involved in cyst dormancy and hatching,

131 it is therefore important to understand the molecular events involved in HSV-1 entry into this cell

132 the orchestration of the early cellular and molecular events involved in immune protection against i

133 Some molecular events involved in initiating emergency granul

134 ated epigenomic approach to characterize the molecular events involved in LPS-induced tolerance in a

135 le to the host tissue and somehow underlying molecular events involved in tissue repair.

136 lpha3GlyRs, our current understanding of the molecular events involved is limited.

137 MSC (hMSC) delivery formula by investigating molecular events involving hMSCs incorporated in a uniqu

138 introduction of agents targeted at specific molecular events is changing the treatment paradigms in

139 also demonstrate that perturbation of a key molecular event known to be critical for effective neutr

140 ctivity at target gene promoters is the only molecular event known to underlie the oncogenic function

141 and experimental strategy that describes the molecular events leading from OPV to virulent strains.

142 uggest that the presence of AIRE can trigger molecular events leading to an altered chromatin landsca

143 reflected cellular turnover in the blood and molecular events leading to episomal DNA stabilization f

144 kines that trigger a cascade of cellular and molecular events leading to extensive migration and infi

145 The molecular events leading to flares are unknown.

146 The molecular events leading to hormone sorting and secretor

147 nsive regulatory sites, causing a cascade of molecular events leading to microglia activation, perine

148 n PSC state and allows new insights into the molecular events leading to naive cell resetting.

149 rsor to OAC, but our understanding about the molecular events leading to OAC development is limited.

150 We have completed a detailed analysis of the molecular events leading to the above response.

151 of plant innate immunity with a focus on the molecular events linking the circadian clock and defense

152 An array of cellular and molecular events mediate this response to collectively g

153 his organism could unveil novel cellular and molecular events mediated by folate and lead to new ways

154 mation of the face and palate, but the basic molecular events mediating this crosstalk remain poorly

155 ulation of focal adhesions (FAs) are crucial molecular events modulating cell adhesion in cancer meta

156 hasing of the behavioral, developmental, and molecular events needed for the proper coordination of p

157 portion of which may represent a cascade of molecular events occasioned by death.

158 regs, or both and what early Notch-regulated molecular events occur in alloantigen-specific T cells.

159 d MMP13 production we examined the potential molecular events occurring between the rapid, transient

160 ngs contributes to a better understanding of molecular events occurring during diapause and diapause

161 ata contribute to the evolving model for the molecular events occurring early in the T cell activatio

162 ng NK cells and to quantitatively assess the molecular events occurring in multi-cellular clusters of

163 sm and host cellular tropism, as well as the molecular events occurring in the viral infectious life

164 udy thus provides atomistic details of early molecular events occurring within the NT during and foll

165 roaches we determined the precise sequential molecular events of a new estrogen signaling network in

166 are consistent with the hypothesis that the molecular events of chromosome morphogenesis are governe

167 etailed structural insights into the initial molecular events of GPCR function that are not easily ac

168 resence of Star-PAP expression, and reverses molecular events of hypertrophy in cardiomyocytes.

169 ed us to observe in real time the individual molecular events of RAG-mediated cleavage.

170 Understanding the molecular events of reproduction requires a system to di

171 We aimed to study the molecular events of SAE to capture its onset and progres

172 nalysis provide new structural basis for the molecular events of the GPCR signaling pathway.

173 r study provides a comprehensive view of the molecular events of the IL-17 signal transduction and it

174 Here, we sought to define the molecular events of this effect in an in vivo mouse inju

175 ng the acquisition of new knowledge into the molecular events of viral infection.IMPORTANCE "Giant" p

176 ssed the question of the predictive value of molecular events on the benefit of the addition of gemtu

177 hat couple the hydrolysis of GTP to specific molecular events on the ribosome.

178 ellular events based on integrating discrete molecular events over several time scales.

179 ) combinations of RNA inputs, and a temporal molecular event recorder that records in the PER transcr

180 pathogenesis of many inflammatory disorders, molecular events regulating mitochondrial activity to co

181 e, such as filamin, in H-PSCs suggested that molecular events related to early apoptosis were also in

182 ogy is the inciting event driving downstream molecular events related to synaptic activity embedded i

183 tibility to disease; however, the underlying molecular events remain largely unknown.

184 ignalling network dynamics, although the key molecular events remain poorly understood.

185 The identity of these molecular events remains for the most part unknown.

186 the components of OCR dedicated to specific molecular events remains lacking.

187 efore, repurposing US9 to track/modify these molecular events represents a valid approach to investig

188 ate the hierarchy and temporal importance of molecular events required for clathrin-coated pit initia

189 The molecular events required for the formation and function

190 anding of the relative importance of the key molecular events required to induce target degradation.

191 The identification of the molecular events responsible for strain emergence, enhan

192 lesion severity is to identify cellular and molecular events responsible for tissue damage and to ma

193 However, the range of possible molecular events resulting from genome editing has been

194 ult slices was used to determine the precise molecular-events sequence responsible for the rapid spin

195 However, single-driver molecular events specific to these subtypes have not bee

196 However, the molecular events subsequent to trypsin activation and th

197 mania promastigotes revealed that it induced molecular events, such as a loss in mitochondrial membra

198 Three molecular events take place upon encountering a target:

199 We identify cell migration as a key molecular event that is activated in mesenchymal progeni

200 ts in bilayers, and suggest that the initial molecular event that leads to neuronal damage does not i

201 However, the major molecular event that occurs during physiological or path

202 However, the molecular events that accompanied this emergence remain

203 man CMV and murine CMV is first triggered by molecular events that activate CMV gene expression and l

204 scriptions are vastly simpler than the multi-molecular events that actually occur and are often hard

205 ively, our studies offer novel insights into molecular events that are linked to fibrosis development

206 atures, which in turn reflected the scope of molecular events that are perturbed in the presence of a

207 centuries, yet knowledge of the cellular and molecular events that build the human brain during embry

208 By focusing on molecular events that change among most mutants and in b

209 The molecular events that characterize postripening grapevin

210 ts depends on understanding the cellular and molecular events that connect innate and adaptive immune

211 We characterized the sequence of molecular events that connected the induced CD44(Hi) phe

212 sorder; however, little is known about early molecular events that contribute to the pathology of the

213 and Src signaling mediated the cellular and molecular events that contributed to the IL-4-dependent

214 However, the intracellular molecular events that culminate in tolerance and functio

215 er understanding of the complex cellular and molecular events that determine T-cell tolerance.

216 Elucidating the molecular events that distinguish how individual ATGs fu

217 However, the molecular events that distinguish Musashi-mediated trans

218 The molecular events that drive hypertrophy decompensation a

219 ing proteins remain unclear, as the specific molecular events that drive neurodegeneration have been

220 The cellular and molecular events that drive the early development of inn

221 ron loss, but the spatiotemporal ordering of molecular events that drive these processes in intact sp

222 Our understanding of the molecular events that enable host switching are often li

223 However, the molecular events that ensure appropriate stimulus- and d

224 Our study provides insights into the molecular events that follow the loss of ESRRB binding,

225 offers novel insights into the nature of the molecular events that follow transcription factor bindin

226 dothelial cell development and highlight the molecular events that govern hemogenic specification of

227 dary-structure elements in globular proteins-molecular events that have previously been inaccessible

228 relates to our current understanding of the molecular events that have since been elucidated.

229 ide insights and approaches for defining the molecular events that impact translation elongation thro

230 ntly, little is known about the cellular and molecular events that influence the induction of reconso

231 nt of obesity-related complications, but the molecular events that initiate and propagate such inflam

232 ings provide a new way of thinking about the molecular events that initiate catastrophe.

233 Little is known about the molecular events that initiate mesenchymal stem cells to

234 Despite the importance of Swi1, the molecular events that lead to [SWI(+) ] prionogenesis re

235 by an endothelial cell undergoes a series of molecular events that lead to a change in phenotype towa

236 The molecular events that lead to B cell lymphoma are only p

237 esenting an opportunity to investigate early molecular events that lead to cataractogenesis.

238 yo development involves complex cellular and molecular events that lead to the establishment of three

239 The molecular events that lead to the induction of this phen

240 However, the upstream molecular events that link cellular stretch to the lengt

241 rrelations between these inputs, and defines molecular events that may underpin complex disease risk.

242 nd gain an in-depth understanding of the key molecular events that modulate CKD pathogenesis.

243 The molecular events that occur during UVB-induced skin carc

244 olic signaling networks and the cellular and molecular events that occur in the setting of altered nu

245 gh the CCR4-NOT deadenylase complex, but the molecular events that occur on target mRNAs are poorly r

246 phy and electron microscopy to elucidate the molecular events that occurred during evolution of this

247 o be determined before Foxp3 expression; yet molecular events that prime Foxp3(-) Treg precursor cell

248 rtant roles in tumorigenesis, the respective molecular events that regulate aberrant cancer cell prol

249 Understanding the molecular events that regulate all these stages requires

250 ction has been well studied, and many of the molecular events that regulate passage of leukocytes out

251 However, little is known about the molecular events that regulate PTEN signaling during lym

252 f the SAC occurs through a series of ordered molecular events that result in recruitment of Mad1:Mad2

253 sion of their cell membranes, triggering the molecular events that result in the formation of a new g

254 However, the series of molecular events that result in this neurological disord

255 Understanding the molecular events that take place at the YAP:TEAD interfa

256 ver, gaps remain in our understanding of the molecular events that take place between ligand-receptor

257 olecular dynamics simulations to unravel the molecular events that take place in different VGICs when

258 We wanted to unravel the sequence of molecular events that take place when formation of inhib

259 Minireview, we discuss how understanding the molecular events that trigger NMD can facilitate strateg

260 However, the early molecular events that trigger the demyelination program

261 sequential embryonic stages to decipher the molecular events that underlie bat wing development.

262 del that allows further investigation of the molecular events that underlie MN.

263 Our understanding of the molecular events that underpin erythrocyte invasion rema

264 SE reorganization is regulated by two molecular events: the establishment of meiosis-specific

265 d as a progressive effect from an initiating molecular event through biological key events toward the

266 The molecular events through which TKS proteins direct colla

267 lioma that exhibits common key pro-oncogenic molecular events throughout the latency period of diseas

268 from cellular to global and timescales from molecular events to decades.

269 xpand the HCM research focus beyond a single molecular event toward more inclusive models to explain

270 These results illustrate the initial molecular event underlying platelet shear sensing and pr

271 upon autophosphorylation at Thr305/306 as a molecular event underlying the threshold shift.

272 netic model organism with which to study key molecular events underlying amyloidogenesis is crucial f

273 However, the molecular events underlying carcinogenesis and their int

274 Thus, we have catalogued the molecular events underlying cell death induced by CQ in

275 However, the molecular events underlying HIV neuropathogenesis remain

276 three-dimensional model is an assay for the molecular events underlying human axial symmetry breakin

277 lopment and adult heart repair; however, the molecular events underlying its maturation remain unknow

278 e findings highlight the complex and dynamic molecular events underlying mammalian differentiation th

279 interstitium promotes fibrogenesis, defining molecular events underlying PPM1A/PTEN deregulation is n

280 Our findings provide key insight into the molecular events underlying regulation of V-ATPase activ

281 A mechanistic understanding of the molecular events underlying signaling, however, has been

282 Important molecular events underlying specific SAS responses have

283 anscriptome of Sgo1(-/+) mice to examine the molecular events underlying the altered carcinogenesis p

284 cognitive performance, but the cellular and molecular events underlying the experience-dependent enh

285 sms that produce alphasyn misfolding and the molecular events underlying the neuronal damage caused b

286 pathologies, it is important to uncover the molecular events underlying the regulation of proteasome

287 ator, providing a platform for investigating molecular events underlying the repair impact of nondiff

288 verse patterning of skin appendages, but the molecular events underlying their specification remain l

289 The molecular events underlying these effects are incomplete

290 However, the precise molecular events underlying these interactions remain la

291 The molecular events underlying these responses are the acti

292 The molecular events underlying this regenerative capacity r

293 Our knowledge of the molecular events underlying type 2 diabetes mellitus-a p

294 gnificantly advance our understanding of the molecular events underpinning ligand-induced DDR1 kinase

295 To understand the molecular events underpinning TGF-beta1-induced fibrogen

296 However, the fundamental molecular events underpinning the early stages of their

297 : the relative temporal ordering of cell and molecular events was not absolute, suggesting cell progr

298 However, molecular events which regulate plant development downst

299 of the spatial and temporal location of key molecular events, which may guide the evaluation of new

300 gnal bias offers opportunities for sculpting molecular events, with the promise of better, safer ther