ライフサイエンスコーパス: molecular machinery

1 t active zones are orchestrated by a complex molecular machinery.

2 ncy require precise coordination of a cell's molecular machinery.

3 Cell division depends on sophisticated molecular machinery.

4 s, is an integral component of the circadian molecular machinery.

5 ell understood, including its efficiency and molecular machinery.

6 rtaken, highlighting new elements in the PCD molecular machinery.

7 ent scaling up and scaling down use distinct molecular machinery.

8 as the lethal hit of CTLs but with distinct molecular machinery.

9 panding our insight into the cell senescence molecular machinery.

10 mobilized by distinct signals through unique molecular machinery.

11 g elaborate and only partially characterized molecular machinery.

12 ythmicity and may be controlled by different molecular machinery.

13 are produced simultaneously, and by the same molecular machinery.

14 understanding cellular perturbation and its molecular machinery.

15 gene transcripts in relation to interacting molecular machineries.

16 a stepwise process that coordinates multiple molecular machineries.

17 he directionality observed in RNA-processing molecular machineries.

18 ndocrine dense core vesicles despite similar molecular machineries.

19 Here we study the cellular and molecular machinery activated by the VEGF pathway during

20 ant cells have developed specific protective molecular machinery against environmental stresses.

21 ted mechanisms that are categorized by their molecular machineries and differing effects on physiolog

22 In kinetoplastid mitochondria, most of the molecular machineries and gene expression processes have

23 Consequently, elaborate molecular machineries and mechanisms emerged during the

24 e mediated by distinct pre- and postsynaptic molecular machineries and to have a specialized role in

25 engulfing NPs and other large cargo, yet its molecular machinery and involvement in NP uptake are far

26 ts cognate ligands are processed by the same molecular machinery and may antagonistically regulate ea

27 pruning share components of their underlying molecular machinery and may thus represent two developme

28 We find that despite very different molecular machinery and modes of action (catalytic vs st

29 ment is particularly important in autonomous molecular machinery and molecular computation, in which

30 Commonalities in molecular machinery and processes across FraX and Willia

31 h recent emphasis given to understanding its molecular machinery and regulation.

32 perties, our understanding of the underlying molecular machinery and signalling pathway in CB glomus

33 Gleason pattern 3 cells typically lack the molecular machinery and the genetic abnormalities, which

34 le back to the plasma membrane; however, the molecular machinery and trafficking pathways utilized by

35 contrasts in the phenotype, neurocircuitry, molecular machinery, and cellular processes in these two

36 ous, often little is known of the associated molecular machinery, and so far, organismal self-recogni

37 cesses and functional similarities among its molecular machinery are apparent across all cellular lif

38 f predator-prey interactions on cellular and molecular machinery are poorly understood.

39 enable analyses of where and when different molecular machineries associate with and act on the BR p

40 Instead, copper selectively up-regulates molecular machinery associated with the cell cycle and c

41 However, little is known on the molecular machinery at the host cell-parasite interface.

42 e summarize the current understanding of the molecular machineries behind each of these types of auto

43 cell death, apoptosis and necroptosis, share molecular machinery but diverge in outcome with importan

44 Interfering with the molecular machinery by which AR drives CaP progression m

45 ll-induced platelet secretion (TCIPS) or the molecular machinery by which effector molecules are rele

46 ession and reveal additional features of the molecular machinery by which photoreceptors mediate phot

47 How the same molecular machinery can elicit such specific and distinc

48 We demonstrate that the essential molecular machinery can, in theory, fit into 0.06 microm

49 in aggregates can be resolved or degraded by molecular machinery conserved from bacteria to eukaryote

50 Thus, a common molecular machinery contributes to the nuclear maturatio

51 e data link cell surface Ret activation with molecular machinery controlling cytoskeletal dynamics an

52 tion, providing fundamental insight into the molecular machinery controlling ER and plasma membrane c

53 signaling may regulate internalization, the molecular machinery coordinating these two processes rem

54 As a part of this molecular machinery, CSA and CSB contribute to the ubiqu

55 o this crucial process, we have analyzed the molecular machinery directing polarized transport of RNA

56 chondrial apoptogenic proteins, although the molecular machinery downstream of JNK has not been preci

57 Many components of the molecular machinery driving cellularisation have been id

58 Thus, the cellular and molecular machinery driving hepatic functions is of utmo

59 The molecular machinery driving PDAC metastasis is still poo

60 ture, dynamics, and energetics of the Hsp104 molecular machinery, even during functional cycling.

61 There are two molecular machineries for pre-mRNA splicing-the major sp

62 cently, advances in our understanding of the molecular machineries for several gliding bacteria revea

63 e-dependently and coordinately regulates the molecular machinery for 2-AG signaling via tropomyosine

64 ing upstream of core components of the fly's molecular machinery for auditory transduction and amplif

65 sts that most, if not all, components of the molecular machinery for autophagy also mediate autophagy

66 The molecular machinery for biosynthesis of both components

67 Thus the cER network serves to organize the molecular machinery for both insertion and removal of ce

68 We propose that the molecular machinery for dopamine secretion has evolved t

69 several key elements of the currently known molecular machinery for endocannabinoid synthesis are th

70 Whereas the molecular machinery for exocytosis in presynaptic termin

71 ateral prefrontal cortex (dlPFC) express the molecular machinery for feedforward, cAMP-PKA-calcium si

72 Much of the molecular machinery for motility evolved in early eukary

73 a also contain SAMs expressing the analogous molecular machinery for NE clearance, which thus constit

74 the downregulation of key components of the molecular machinery for necroptosis.

75 ized primarily in the cell body, whereas the molecular machinery for neurite extension and elaboratio

76 communication in the brain, require complex molecular machinery for neurotransmitter release and rec

77 olite-engineering approach would require the molecular machinery for producing and responding to NHP

78 ve capacities, but in lower vertebrates, the molecular machinery for regeneration is an elemental par

79 at twinfilin can be an essential part of the molecular machinery for regulating filament lengths afte

80 ic sites on the membrane that have clustered molecular machinery for secretion [15], organized in par

81 Nature provides highly evolved, finely tuned molecular machinery for solar energy conversion that exq

82 ploys specialized sites for release, and the molecular machinery for somatodendritic release is not u

83 Because complexins bind to the molecular machinery for synaptic vesicle fusion (the SNA

84 However, the molecular machinery for the production of oxygenated pol

85 Toward determining whether the molecular machinery for vesicular transmitter release is

86 We are learning to build synthetic molecular machinery from DNA.

87 spite similar fundamental organizations, the molecular machinery, functions, and evolutionary charact

88 tors of subtype 5 (mGluR5) contribute to the molecular machinery governing sleep-wake homeostasis.

89 comparatively little is known regarding the molecular machinery governing this process.

90 However, the construction of crystalline molecular machinery has been challenging due to the diff

91 te these diverse functions, and an extensive molecular machinery has developed to support the assembl

92 This molecular machinery, however, is suspected to be a sourc

93 urse of differentiation by deploying diverse molecular machineries in a variety of developmental cont

94 n, we show that in vivo manipulation of this molecular machinery in mice results in cardiomyocyte ded

95 ructural and dynamical information about the molecular machinery in plants and gain high-resolution i

96 y, these data provide insights into the SSBR molecular machinery in the cell and point to the involve

97 dinary capacity of HIV to exploit the cell's molecular machinery in the course of infection.

98 novel insights into evolution of the meiotic molecular machinery in the ecologically important Symbio

99 many hundreds of proteins that assemble into molecular machinery in the host cell that permit protein

100 y defining for the first time the endogenous molecular machinery in the stroke-denervated cervical sp

101 several open questions remain regarding the molecular machinery in these systems, including fundamen

102 i requires CRISPR- and transposon-associated molecular machineries, including a co-complex between th

103 ta suggest that alterations of the DAXX/ATRX molecular machinery increase the malignant potential of

104 ides an optimal system for understanding the molecular machineries involved in blood progenitor commi

105 Whereas the molecular machineries involved in membrane fusion/fissio

106 y post-genomic era is the description of the molecular machineries involved in these processes.

107 define the transcriptional program encoding molecular machinery involved in alpha-synuclein patholog

108 dy represents a major step in unraveling the molecular machinery involved in anaerobic NO(3)(-) and N

109 s recognized role in enamel development, the molecular machinery involved in Ca2+ homeostasis in amel

110 ancer therapy, a better understanding of the molecular machinery involved in chemotherapy-related sen

111 Here we show that part of the molecular machinery involved in ciliogenesis also partic

112 This report demonstrates conservation of the molecular machinery involved in erythrocyte invasion by

113 The molecular machinery involved in establishing and maintai

114 The molecular machinery involved in GLUT4 vesicle tethering

115 However, the trafficking molecular machinery involved in lysosome exocytosis and

116 However, the molecular machinery involved in regulating caveolar upta

117 ating the plasma membrane recruitment of the molecular machinery involved in Rim101 processing and ac

118 In this Review, we discuss the molecular machinery involved in the generation of new ne

119 gested that LMO4 was an integral part of the molecular machinery involved in the negative regulation

120 he past decade has seen understanding of the molecular machinery involved in the pathogenesis of gene

121 However, the signals and the molecular machinery involved in the redox-dependent regu

122 spindle, although little is known about the molecular machinery involved in this process.

123 aining embryonic stem cell pluripotency, the molecular machinery involved remains poorly understood.

124 transport rather than directly affecting the molecular machinery involved.

125 Therefore, defining the dynamics of such molecular machinery is critical for understanding cell-s

126 nce these pathways converge and share common molecular machinery, it is unclear if autophagy-related

127 tributed to the inappropriate acquisition of molecular machinery leading to metastatic transformation

128 e a crucial role in conferring dynamicity to molecular machineries like nucleic acid packaging motors

129 however, little is know about the underlying molecular machinery linking these two cytoskeletal syste

130 Here, we report synthetic molecular machinery made from DNA that controls and reco

131 , and/or, when possible, to have induced the molecular machinery mediating such effects to rely oppor

132 ed by GLUT4 translocation in muscle, but the molecular machinery mediating this process is poorly und

133 s can have a wide range of applications like molecular machinery, nano robotics, and material assembl

134 s demonstrate that TI cells not only contain molecular machinery necessary for active ion transport,

135 his was associated with the induction of the molecular machinery necessary for PC formation.

136 damental step in the quest to understand the molecular machinery of a cell.

137 rch aimed at understanding and improving the molecular machinery of Agrobacterium responsible for the

138 in complex multicellular organisms, the core molecular machinery of autophagy - the 'autophagy protei

139 we summarize our current knowledge about the molecular machinery of autophagy and the role of the aut

140 Stim and Orai proteins comprise the molecular machinery of Ca(2+) release-activated Ca(2+) (

141 detailed physiological observations with the molecular machinery of Ca(2+)-triggered exocytosis.

142 and worms continue to dissect the intricate molecular machinery of chemical synapses.

143 Although the molecular machinery of dendritic patterning in c1vpda ha

144 SNARE proteins are the conserved molecular machinery of exocytosis in the majority of sec

145 substantiated information on the specialized molecular machinery of gametocytogenesis and expedited t

146 cal and genetic analyses have determined the molecular machinery of IFT, but these studies do not exp

147 ta is an important step in understanding the molecular machinery of life.

148 ets coated with Atg8/LC3, a component of the molecular machinery of macroautophagy, and maintains pha

149 tein receptor (SNARE) complexes are the core molecular machinery of membrane fusion, a fundamental pr

150 ng complex required for transport (ESCRT), a molecular machinery of multiple subcomplexes (ESCRT-I/II

151 Recent evidence suggests that the molecular machinery of RNA interference may function as

152 onventional synapses by interacting with the molecular machinery of synaptic vesicle fusion at the ac

153 ion of plant microbiome on re-triggering the molecular machinery of Taxol biosynthesis, their transcr

154 to explain both relatively simple modules of molecular machinery of the cell and to achieve system-le

155 that has been made in understanding how the molecular machinery of the cell cycle is used in the pro

156 ding of the organization, communication, and molecular machinery of the liver.

157 A promising donor organism for the molecular machinery of this mechanism is the eukaryotic

158 checkpoint complex, an essential part of the molecular machinery on which the SAC relies.

159 ets of genes is limited, and the cooperating molecular machinery or specific genomic anchoring sequen

160 est that the cuticulosome and the associated molecular machinery regulate the concentration of iron w

161 our findings deepen our understanding of the molecular machinery regulating endocytosis and subsequen

162 Recent studies have begun to describe the molecular machinery regulating hypha orientation.

163 uestered before degradation, to identify the molecular machinery regulating sequestration, and to ana

164 The molecular machinery regulating these cell death programs

165 by ligands has been studied extensively, the molecular machinery regulating TRPA1 is only poorly unde

166 Consistent with this, the molecular machineries required for establishing segmenta

167 However, the molecular machinery required and possible trafficking ro

168 ated in this process, the composition of the molecular machinery required for efficient directional t

169 Here, we define the minimal molecular machinery required for FGF2 membrane transloca

170 P), is an essential feature of the conserved molecular machinery required for gliding motility and ce

171 blish PRMT8 as an important component of the molecular machinery required for hippocampal neuronal fu

172 platform yields functional insight into the molecular machinery required for HM biosynthesis in plan

173 tion program is essential for assembling the molecular machinery required for meiotic progression, fe

174 , confirming that these enterocytes have the molecular machinery required for phagocytosis.

175 In an effort to define the precise molecular machinery required for platelet exocytosis, we

176 mice, and may help to better understand the molecular machinery required for rabies virus spread in

177 These results indicate that the molecular machinery required for the assembly of the mit

178 Thus, subplate neurons regulate molecular machinery required to establish an adult balan

179 ol cell direction have been established, the molecular machinery required to generate the force of th

180 The molecular machinery responsible for DNA expression, reco

181 The molecular machinery responsible for DNA replication, the

182 ntly over the past two decades; however, the molecular machinery responsible for driving the system r

183 cades of research have uncovered much of the molecular machinery responsible for establishing and mai

184 at the heart of the RNA interference (RNAi) molecular machinery responsible for gene silencing.

185 The molecular machinery responsible for myonuclear positioni

186 uman cDNA encoding the mammalian enzyme, the molecular machinery responsible for regulating this acti

187 Recent studies have unveiled the molecular machinery responsible for the biological clock

188 agation of spreading depolarization, but the molecular machinery responsible for the dendritic beadin

189 The molecular machinery responsible for the oocyte transcrip

190 nrecognized link between neuronal NO and the molecular machinery responsible for the sustained synapt

191 Our evolving understanding of the molecular machinery responsible for the tightly controll

192 TCDD exposure suggest a direct effect on the molecular machinery responsible for these rhythms.

193 The basic pathways and molecular machinery responsible for transporting lipopol

194 rs at a similar rate, suggests that the same molecular machinery serves to partition and place many,

195 The molecular machinery synapses use to convey information f

196 findings provide the first insight into the molecular machinery targeted by Rap signaling to modulat

197 Yet the molecular machineries that allow each cell to merge info

198 er, and the mouse have not only revealed the molecular machineries that cause the programmed demise o

199 We propose a direct link between the molecular machineries that control cell cycle progressio

200 Overall, water flow is detected by molecular machinery that can vary between hair cells of

201 Until recently, however, the molecular machinery that carries out reversible palmitoy

202 Although much is understood about the molecular machinery that confers HIF responsiveness to o

203 Little is known about the molecular machinery that contributes to site-specific co

204 mic study revealed candidate proteins of the molecular machinery that control the Golgi disassembly a

205 However, the molecular machinery that controls active transport of re

206 s, the discovery and characterization of the molecular machinery that controls cellular polarization

207 eristic that can be regulated by the complex molecular machinery that controls gene expression.

208 However, the molecular machinery that controls Ras ubiquitination has

209 The molecular machinery that controls secondary necrosis sta

210 The molecular machinery that controls the alpha-actin switch

211 lays a foundation for future studies on the molecular machinery that controls the development of the

212 However, little is known about the molecular machinery that controls the homeostasis of int

213 Our data reveal a molecular machinery that controls the photoperiodic regu

214 oroplast movement is beginning to define the molecular machinery that controls these movements.

215 s or Ab-secreting plasma cells; however, the molecular machinery that controls this cellular fate is

216 pends crucially on microtubule dynamics, the molecular machinery that couples SGs to microtubule-depe

217 To identify the molecular machinery that defines Muller glial cell ident

218 However, the molecular machinery that determines the type of PCD is p

219 Circadian clocks constitute the evolutionary molecular machinery that dictates the temporal regulatio

220 organs, relatively little is known about the molecular machinery that directly governs metabolic plas

221 The molecular machinery that directs formation of definitive

222 t extension relies on the same intracellular molecular machinery that directs planar cell polarity (P

223 To define the molecular machinery that directs repair, we applied lase

224 -dependent reversible phosphorylation of the molecular machinery that drives invasion and egress.

225 trate that LOXL2 is a novel component of the molecular machinery that forms cross-linked collagen IV

226 Much is known about the molecular machinery that forms the central spindle, incl

227 Here, we focused on characterizing the molecular machinery that functions in the sequential syn

228 The answers lie in the molecular machinery that generates neural crest cells, c

229 ences in transcriptional programming and the molecular machinery that governs the migration, adhesion

230 Here, we review the molecular machinery that gut bacteria use to degrade sta

231 we present studies aimed at elucidating the molecular machinery that is responsible for the HG-induc

232 However, the molecular machinery that links these processes is unknow

233 e that these new SR-TT junctions contain the molecular machinery that mediate SOCE: stromal interacti

234 The molecular machinery that mediates sperm-egg interactions

235 Little is known, however, about the molecular machinery that mediates the formation of a lar

236 leal tissue provides novel insights into the molecular machinery that mediates their functions and sp

237 The molecular machinery that mediates this organelle fission

238 ittle is known about their biogenesis or the molecular machinery that modulates this process.

239 HSPA1A) and Hsp110 (HSPH1) formed a powerful molecular machinery that optimally reactivated stable lu

240 myogenic transcription factor signaling, the molecular machinery that orchestrates the discrete proce

241 ies has shed light on the details of how the molecular machinery that orchestrates these attachments

242 The molecular machinery that organizes the signaling molecul

243 Cytokinesis is monitored by a molecular machinery that promotes the degradation of the

244 They also indicate that the molecular machinery that promotes the wrapping of the gl

245 have proven instrumental for unraveling the molecular machinery that regulates actin polymerization.

246 l cell types, the Par complex is part of the molecular machinery that regulates cell polarity and mai

247 We propose that DBC1 is part of the molecular machinery that regulates fat storage capacity

248 er, little is known regarding the underlying molecular machinery that regulates its stability.

249 The elucidation of the molecular machinery that regulates response to hypoxia h

250 The molecular machinery that regulates the entry and surviva

251 rized type of adult stem cell, the intricate molecular machinery that regulates their self-renewal pr

252 Currently, the molecular machinery that regulates this sorting pathway

253 The molecular machinery that shapes the endoplasmic reticulu

254 anchorage to the cytoskeleton; however, the molecular machinery that supports this process remains e

255 s of the gamma-secretase core complex with a molecular machinery that targets and fuses synaptic vesi

256 een described, little is known regarding the molecular machinery that terminates Arc function.

257 PM, indicating that it is a component of the molecular machinery that tether SGs to the PM.

258 d glial cells, suggesting the existence of a molecular machinery that transfers it to and retains it

259 talyzed by the spliceosome, a highly dynamic molecular machinery that undergoes dramatic conformation

260 Over the past two decades, the molecular machinery that underlies autophagic responses

261 plex is important for the elucidation of the molecular machinery that underlies synaptic transmission

262 cription of the cell from the perspective of molecular machinery (the mechanome) is likely to emerge

263 es behind the promising field of crystalline molecular machinery, the analytical methods to analyze r

264 Furthermore, a unique molecular machinery, the editosome, catalyzes the proces

265 e codon usage in the context of their host's molecular machinery, their genomes provide another windo

266 , inaccessible chromatin sites, enabling the molecular machinery to act on functionally significant i

267 ssible to relate the dynamic organization of molecular machinery to cellular function.

268 and the OS share common building blocks and molecular machinery to construct and maintain them.

269 her way in which the virus exploits the host molecular machinery to expand its limited genetic repert

270 How ZIKV interacts with the host molecular machinery to impact neurogenesis in vivo is no

271 he Pooideae ancestor may have possessed some molecular machinery to mitigate cold stress.

272 dysregulating neutrophil gene expression and molecular machinery to potentially maximize its survival

273 strates that self-renewing mESCs possess the molecular machinery to sense shear stress and provides q

274 ization, domestication, as well as about the molecular machineries underlying them.

275 Together, our data suggest that the molecular machinery underlying axonal insulation and axo

276 d to reveal further important aspects of the molecular machinery underlying lineage commitment.

277 sease is therefore crucial to dissecting the molecular machinery underlying LSC self-renewal.

278 In the quest to identify the molecular machinery underlying mechanoelectrical transdu

279 Integrating these findings with the molecular machinery underlying migration will provide a

280 However, the molecular machinery underlying MT dynamics in tip-growin

281 Akinduro et al. detail the molecular machinery underlying removal of the nucleus (n

282 cience states that synaptic vesicles and the molecular machinery underlying spontaneous transmitter r

283 havior, yet there is much to learn about the molecular machinery underlying the coordination between

284 nome have generally been hypothesized as the molecular machinery underlying the persistent, often tis

285 To gain a better understanding of the molecular machinery underlying the pleiotropic functions

286 However, the molecular machinery underlying these hierarchically thre

287 velopmental processes in plants, the broader molecular machinery underpinning polarity establishment

288 Furthermore, the molecular machinery used by normal stem cells for homing

289 spindle and broaden our understanding of the molecular machinery used to move chromosomes.

290 ings should prove useful for elucidating the molecular machinery used to transmit a signal into a vir

291 Thus, the molecular machinery utilized by bladder epithelial cells

292 e than three billion years, during which its molecular machinery was perfected to minimize wasteful r

293 rom the fields of molecular conductivity and molecular machinery we set out to design a crystalline m

294 study multi-protein interactions within such molecular machineries, we have developed a fluorescence

295 : (i) that the rods, and their corresponding molecular machinery, were lost or (ii) that the rods wer

296 d accurate means to describe the dynamics of molecular machinery which orchestrates gene regulation.

297 (MDR) efflux pumps are ancient and conserved molecular machineries with relevant roles in different a

298 whether the interval-timing mechanism shares molecular machinery with the circadian timing mechanism.

299 While we know much about the molecular machinery within each compartment, we are only

300 NA and RNA polymerases with their associated molecular machinery would move along the DNA template wi