ライフサイエンスコーパス: molecular recognition

1 e of individual conductance measurements for molecular recognition.

2 important in providing an efficient mode of molecular recognition.

3 considered as hydrogen bond donor groups in molecular recognition.

4 eral hundred Hertz, which typically prevents molecular recognition.

5 has the potential to be used for signalling molecular recognition.

6 ctors for transition-state stabilization and molecular recognition.

7 epigenetic marks and challenging targets for molecular recognition.

8 ydrogen bonds are ubiquitous interactions in molecular recognition.

9 the interior that strongly influenced their molecular recognition.

10 mus (supra-tauc window), strongly influence molecular recognition.

11 of foldamers to outstanding achievements in molecular recognition.

12 link of the observed supra-tauc motion with molecular recognition.

13 formational selection and/or induced fit) of molecular recognition.

14 ly used in protein/ligand design to modulate molecular recognition.

15 he key role of these residues in the peptide molecular recognition.

16 nal selection is an established mechanism in molecular recognition.

17 n bonds play an essential role in biological molecular recognition.

18 teins are proteins that maintain promiscuous molecular recognition.

19 static fields, which play a critical role in molecular recognition.

20 olecular imprinting technique depends on the molecular recognition.

21 olymeric macromolecules capable of exquisite molecular recognition.

22 sed in septins to play a fundamental role in molecular recognition.

23 zable approach to understanding the logic of molecular recognition.

24 hat all of adenine's edges may contribute to molecular recognition.

25 natives to bio-receptors due to the inherent molecular recognition abilities and the high stability i

26 n their structural features as well as their molecular recognition abilities.

27 Molecular recognition, activation and dynamic self-assem

28 Nucleic acid aptamers are versatile molecular recognition agents that bind to their targets

29 for discovery of sulfide protein targets and molecular recognition agents.

30 mited by the affinity and specificity of the molecular-recognition agents for the analyte of interest

31 must possess both the capacity for specific molecular recognition and a dynamic nature to their intr

32 their respective receptors are essential for molecular recognition and are also key contributors to t

33 esence of an autocatalytic network involving molecular recognition and assembly processes, where the

34 action to the ubiquitous hydrogen bonding in molecular recognition and assembly.

35 of 24 amphiphilic polymers, preselected for molecular recognition and based on functional monomers i

36 epresents an unprecedented example of chiral molecular recognition and can disclose innovative approa

37 at are capable of complex functions, such as molecular recognition and catalysis, is provided by sequ

38 nd esters have been extensively utilized for molecular recognition and chemical sensing.

39 y adopting P or M helicity, is described for molecular recognition and chirality sensing.

40 yclic entities that display a combination of molecular recognition and complexation properties with v

41 cular entities that display a combination of molecular recognition and complexation properties with v

42 Molecular recognition and discrimination of carbohydrate

43 c data for biological interactions including molecular recognition and enzymatic catalysis.

44 Here, we characterized the molecular recognition and functional efficacy of the N-C

45 ps binding to BRCT to understand promiscuous molecular recognition and guide inhibitor design.

46 However, the thermodynamics governing the molecular recognition and interaction of lipids with mem

47 The molecular recognition and interactions governing site-sp

48 ey traits of autocatalytic systems including molecular recognition and kinetic saturation.

49 repeat proteins have been re-engineered for molecular recognition and modular scaffolding applicatio

50 templates for nanomaterials due to inherent molecular recognition and self-assembly capabilities com

51 nd short range molecular interactions govern molecular recognition and self-assembly of biological ma

52 loid structures are formed by the process of molecular recognition and self-assembly, wherein a pepti

53 DNA has unique capabilities for molecular recognition and self-assembly, which have fost

54 e stage for uncovering novel determinants of molecular recognition and signalling in single-spanning

55 for investigation of the combined effects of molecular recognition and spatial constraints in biomole

56 wing inspiration from pioneering research in molecular recognition and structural biology.

57 ion should be directly relative to issues of molecular recognition and supermolecular self-assembly.

58 on due to their biocompatibility, functional molecular recognition and unique biological and electron

59 basics of sensors (methods of transduction, molecular recognition, and amplification) is provided fo

60 attractive functional targets for synthesis, molecular recognition, and hierarchical self-assembly.

61 ganization of adsorbed protein, accelerating molecular recognition, and informing the fundamentals of

62 ications including drug delivery, catalysis, molecular recognition, and sensing.

63 se results showcase the contextual nature of molecular recognition, and suggest further that nonnativ

64 lished tools of supramolecular chemistry and molecular recognition, and they are finding increasing a

65 ke the one presented herein are the basis of molecular recognition, and we expect this principle to f

66 This type of molecular recognition appears to enable dual specificity

67 of a library of functional hybrid solids for molecular recognition applications such as sensing, sepa

68 Important for molecular recognition applications, fluorescence quenchi

69 paper exploiting polynorepinephrine (PNE) in molecular recognition applications, taking advantage of

70 potentially deliver functional molecules for molecular recognition applications.

71 , but they lack the precise base pairing and molecular recognition available with nucleic acid assemb

72 eplicating inorganic molecules that work via molecular recognition based on the {PMo(12)} = [PMo(12)O

73 sect the molecular mechanism, we examine the molecular recognition between AFP and trehalose crystal

74 lphaLeu285 residues, an essential region for molecular recognition between alpha-alpha and beta-beta

75 Molecular recognition between cells is thus a fundamenta

76 ]pseudorotaxane employing radically enhanced molecular recognition between the bisradical dication ob

77 such as concanavalin A (Con A) based on the molecular recognitions between the glycan ligands on the

78 Molecular recognition binding sites that specifically id

79 Molecular recognition, binding and catalysis are often m

80 place at lipid membrane surfaces, including molecular recognition, binding, and protein-protein inte

81 ractions in proteins is key to understanding molecular recognition, biological functions, and is cent

82 are increasingly evoked in models of protein molecular recognition but are challenging to experimenta

83 a highly efficient and unusual mechanism of molecular recognition by an antibody.

84 kbone structure and the role of the sugar in molecular recognition by antibodies are emphasised.

85 op an antibody-free approach using synthetic molecular recognition by constructing a polymer to mimic

86 ter infection in order to define the mode of molecular recognition by enhancing antibodies.

87 Molecular recognition by proteins is fundamental to mole

88 ole for conformational entropy in modulating molecular recognition by proteins is in opposition to an

89 the general role of entropy in high-affinity molecular recognition by proteins.

90 Recognition (CoPhMoRe) approach of synthetic molecular recognition by screening ssDNA-wrapped SWCNTs

91 ation would generate P450 phosphodegrons for molecular recognition by the E2-E3 complexes, thereby co

92 V-Nb23 complex, which provides the basis for molecular recognition by the Nb.

93 Information in the process of molecular recognition can be transmitted to us via physi

94 is work conclusively shows that corona phase molecular recognition can mimic key aspects of biologica

95 iner precursors, are known for their tunable molecular recognition capabilities towards an array of g

96 ertiary structural behavior and programmable molecular recognition capabilities.

97 imprinted polymers (MIPs) have a predesigned molecular recognition capability that can be used to bui

98 MFC is partially replaced by an ionomer with molecular recognition capability working as the biorecog

99 In our PIERS sensor, we exploit the molecular recognition capacity of aptamers and the high

100 oup interactions can play important roles in molecular recognition, catalysis and self-assembly.

101 Integrating molecular recognition, catalysis, and assembly, these ac

102 Control experiments demonstrated the molecular recognition characteristic inferred by the enz

103 rganization and predisposition are important molecular recognition concepts exploited by nature to ob

104 We herein show an example of such molecular recognition-controlled kinetic assembly/disass

105 Specific binding between biomolecules, i.e., molecular recognition, controls virtually all biological

106 then extend this system to the Corona Phase Molecular Recognition (CoPhMoRe) approach of synthetic m

107 Corona phase molecular recognition (CoPhMoRe) uses a heteropolymer ad

108 ) measurements demonstrate that MOR displays molecular recognition dynamics on two different time sca

109 Molecular recognition (e.g., antigen-antibody, DNA-DNA,

110 performing other complex functions, such as molecular recognition (e.g., aptamers) and catalysis (e.

111 applications for gas storage and separation, molecular recognition, electric and optical materials, c

112 d unbinding events between the alpha-helical molecular recognition element (alpha-MoRE) of the intrin

113 esponses depending on the target analyte and molecular recognition element (MRE) combination.

114 sibility of using aptamers as an alternative molecular recognition element in ELISA.

115 ported to have affinity for human OPN as the molecular recognition element, and the ferro/ferricyanid

116 First, GOx, as a molecular recognition element, catalyzes the oxidation o

117 cterized through the immobilization of their molecular recognition elements (MREs) onto gold disk ele

118 Aptamers have exhibited many advantages as molecular recognition elements for sensing devices compa

119 rgize the properties of both transducers and molecular recognition elements improving the performance

120 conditions, it is a candidate for the use as molecular recognition elements in biosensing platform.

121 ctional and robust porous materials serve as molecular recognition elements that can be used to captu

122 ferent strategies and highlights the leading molecular recognition elements that have potential roles

123 ractions with ancient ligands may reveal how molecular recognition emerged and evolved.

124 tic and therapeutic opportunities abound for molecular recognition entities that can bind glycans wit

125 unique property of life that is crucial for molecular recognition, enzymatic function, information s

126 ed gas-generation reaction with the designed molecular recognition event, obviously the pressure-base

127 actions provides insights into the nature of molecular recognition events and has practical uses in g

128 imensional combinatorial screening to define molecular recognition events between 'undruggable' biomo

129 At the synthetic level, molecular recognition events have been used to induce co

130 proteins and their substrates that drive the molecular recognition events leading to ubiquitin transf

131 However, little is known about the molecular recognition events that mediate phage adsorpti

132 Daisy-chaining multiple molecular recognition events together in synthetic circu

133 y is uniquely suited for detecting transient molecular recognition events, yet achieving the time res

134 a conditional manner to detect and quantify molecular recognition events.

135 he proper presentation of the sugar unit for molecular recognition events.

136 s to transcriptionally interconnect multiple molecular recognition events.

137 Our results show that a partially structured Molecular Recognition Feature (MoRF) within an intrinsic

138 Molecular recognition features (MoRFs) provide interacti

139 action-prone protein IDPRs are identified as molecular recognition features (MoRFs).

140 The review presents the basic physical and molecular recognition features of the supramolecular hos

141 lts advance the mechanistic understanding of molecular recognition for a major class of splice site s

142 ch utilizes molecular reactivity rather than molecular recognition for analyte detection-has rapidly

143 aditional biosensors thus, offering enhanced molecular recognition for insulin, improving performance

144 the flexibility and rigidity, and the unique molecular recognition for silicic acid, followed by the

145 mical interactions and can form the basis of molecular recognition for various classes of analytes.

146 The observed molecular recognition fundamentally differs from canonic

147 The molecular recognition has also been investigated by DFT

148 ars ago, but our conceptual understanding of molecular recognition has not kept pace.

149 ssible and yet incorporates highly intricate molecular recognition, immolative, and rearrangement che

150 Programming and controlling molecular recognition in aqueous solutions is increasing

151 Barbiturates are common targets for molecular recognition in preorganized receptors due to c

152 y, may thus be a dominating factor in chiral molecular recognition in such systems.

153 action kinetics, all controlled by selective molecular recognition in the cage interior.

154 onally connected pore network, which enables molecular recognition in the size range 0.5-0.6 nm.

155 monomer species having kinetically selected molecular recognition in the structure-forming step and

156 for technical improvements, including use of molecular recognition, in selective metal separation tec

157 cial replicators have been designed based on molecular recognition, inspired by the template copying

158 The molecular recognition interaction between the peptide (p

159 nfluenced by a cooperative topology based on molecular recognition interactions with Cu(2+)-trisNTA b

160 nate peptide with a component of induced fit molecular recognition involving the adoption of multiple

161 Corona phase molecular recognition is a technique introduced to gener

162 Molecular recognition is an important initial step for t

163 cular dynamics simulations, we show that the molecular recognition is associated with the unique thre

164 It is shown that molecular recognition is based on cooperative hydrogen b

165 Molecular recognition is critical for the fidelity of si

166 Although molecular recognition is crucial for cellular signaling,

167 al calorimetry titrations indicate that this molecular recognition is driven by a favorable enthalpy

168 Understanding the driving forces underlying molecular recognition is of fundamental importance in ch

169 tivity of a hydrogel mediated by competitive molecular recognition is potentially promising toward th

170 Specific molecular recognition is routine for biology, but has pr

171 The process of molecular recognition is the assembly of two or more mol

172 o the broad potential of hydroxyl groups for molecular recognition is their exceptionally high desolv

173 Such molecular recognition lessons are important for engineer

174 fluorine often plays an influential role in molecular recognition, little is known about the effect

175 The dense distribution of molecular recognition loops on the robust peptoid nanosh

176 Together, our data reveal differences in the molecular recognition mechanisms associated with evoluti

177 playing important roles throughout biology, molecular recognition mechanisms in intrinsically disord

178 t can transform into polymer films through a molecular recognition-mediated crosslinking process.

179 Many molecular recognition methods target ribosomal RNA seque

180 d the coactivator Med25, reveals a different molecular recognition model.

181 n of disordered activators and indicate that molecular recognition models of disordered proteins must

182 tential method to "wrap" surfaces displaying molecular recognition motifs-which could potentially inc

183 ng highly deformable microgel particles with molecular-recognition motifs identified through directed

184 Hydrogen bonding is a key governing force in molecular recognition, notably in biological systems.

185 isms underlying cell competition include the molecular recognition of 'different' cells, signalling i

186 Accordingly, we faced the molecular recognition of a target dipeptide (Ac-EY-OH) m

187 aniline and phenylhydrazine dyes that enable molecular recognition of a wide variety of aliphatic or

188 scanned as chiral solvating agents to study molecular recognition of acids by NMR analysis.

189 A and establish the structural basis for the molecular recognition of adenosine ribonucleotides.

190 aphosphonate resorcinarene cavitands for the molecular recognition of amino acids.

191 structure allows us to explore in detail the molecular recognition of antagonists.

192 Many factors govern molecular recognition of biological targets by small mol

193 knowledge has enlightened research into the molecular recognition of biologically active molecules,

194 Molecular recognition of carbohydrates is a key step in

195 Molecular recognition of carbohydrates plays an importan

196 Molecular recognition of carbohydrates plays vital roles

197 recruitment into clusters involves specific molecular recognition of cognate DNA and chromatin-bindi

198 First, we performed a molecular recognition of DCL- and AG-PEGylation on ligan

199 tion of antibody-toxin interactions based on molecular recognition of distinctive toxic motifs are el

200 istry provides an effective strategy for the molecular recognition of diverse molecules.

201 ing represents a recurring key motif for the molecular recognition of glycosides, either by protein b

202 e and identify metalloproteins, based on the molecular recognition of holo- and apo-metalloproteins (

203 Molecular recognition of immature SOD1 by hCCS is driven

204 incentive to further probe the relevance of molecular recognition of KS by galectins in terms of phy

205 evel and provide chemical perspective on the molecular recognition of membrane receptors.

206 evelop an oligonucleotide microarray for the molecular recognition of multiple plant components in co

207 ymer (MIP)-based synthetic receptors for the molecular recognition of neuron specific enolase (NSE) b

208 Our approach relies on selective molecular recognition of one enantiomer of the target mo

209 high binding affinity and thus provides for molecular recognition of OTA; simulating the mycotoxin-s

210 ls and can offer deep understanding into the molecular recognition of pathogen-host receptor interact

211 This Perspective discusses molecular recognition of RNA by small molecules and high

212 in addition to sequence, is critical for the molecular recognition of RNA.

213 The molecular recognition of short peptides is a challenge i

214 Selective molecular recognition of substrates controls the reactiv

215 mesoporous support, protein selectivity, and molecular recognition of substrates).

216 or biomolecule deactivation, is crucial for molecular recognition of target molecules or cells.

217 ding binding assays and an assay that mimics molecular recognition of tau pre-mRNA by a U1 small nucl

218 We report the molecular recognition of the Au(CN)(2)(-) anion, a cruci

219 pecific antibody functionalization, based on molecular recognition of the constant Fc region.

220 n current defined by tauopen, which includes molecular recognition of the incoming dNTP.

221 ds lanthanide and actinide complexes through molecular recognition of the ligands chelating the metal

222 Our findings provide further insight into molecular recognition of the major receptor on the HIV v

223 n a protein IR spectrum, to characterize the molecular recognition of the Src homology 3 (SH3) domain

224 ificity-altering mutations unveiled distinct molecular recognition of the three substrates.

225 This paper describes the molecular recognition of the tripeptide Tyr-Leu-Ala by t

226 ented here provide crucial insights into the molecular recognition of the two cofactors, F420 and NAD

227 nding of the chemical and physical basis for molecular recognition of viral surface proteins in order

228 e cell surface glycosylation and the complex molecular recognition on the intact cell surface, which

229 ied state, but can incorporate peptides with molecular recognition or environmentally responsive prop

230 uning hydrophobic driving forces to optimize molecular recognition or self-assembly processes.

231 on state in directed C-H activation, as core molecular recognition parameters to differentiate betwee

232 zation effects in conformational control and molecular recognition phenomena.

233 of a SpA side chain by an Fc side chain in a molecular-recognition pocket.

234 selectivity and advance our understanding of molecular recognition principles.

235 ide aptamer is an attractive candidate for a molecular recognition probe because of its ease of synth

236 We have demonstrated that this molecular recognition process between alpha-cyclodextrin

237 This molecular recognition process could, in principle, be in

238 e insights into the overall organization and molecular recognition process of the phage varphi11 tail

239 s of DNA represents a very effective natural molecular recognition process widely exploited for diagn

240 acetyllysine-binding pocket that dictate the molecular recognition process, and we examined the bindi

241 nteractions play important roles in numerous molecular recognition processes in chemistry and biology

242 Despite its clear involvement in molecular recognition processes, the critical role of th

243 Examples include molecular recognition processes, which trigger biologica

244 al ions and provide a framework for studying molecular recognition processes.

245 nal groups important in a wide assortment of molecular recognition processes.

246 ons are notoriously difficult to separate in molecular recognition processes.

247 nce of Ser and Thr O-glycosylation points in molecular recognition processes.

248 biochemical cascade formed by the collective molecular recognition properties and proteolytic activit

249 Nanometer-sized features and molecular recognition properties make DNA a useful mater

250 g proteins and DNAs were based on the unique molecular recognition properties of HO to the targets to

251 the synthesis, X-ray crystal structure, and molecular recognition properties of pillar[n]arene deriv

252 Furthermore, the molecular recognition properties of T1R1-T1R3 guided tas

253 The molecular recognition properties of the nucleobases inst

254 porters while avoiding any impairment of the molecular recognition properties of the peptides.

255 lar anion receptors can be used to study the molecular recognition properties of the reactive yet bio

256 ect of porogen on particle size and specific molecular recognition properties.

257 Molecular recognition reagents are key tools for underst

258 The MIP membrane, as a molecular recognition receptor, has a three-dimensional

259 Specific molecular recognition, reversible binding and dose-depen

260 ynthetic polymers for applications including molecular recognition, self-assembly, and catalysis.

261 all molecules in enantioselective catalysis, molecular recognition, self-assembly, material science,

262 s programmable platforms for applications in molecular recognition, sensor and catalyst development a

263 Such nanocages have found widespread use in molecular recognition, separation, stabilization and the

264 espread in nature and have critical roles in molecular recognition, signalling, and other essential b

265 roteins and peptides are key determinants of molecular recognition specificity landscapes.

266 This novel molecular recognition strategy to trigger morphological

267 Molecular recognition studies with IAPP and Abeta1-42 em

268 The fundamental principles guiding the molecular recognition, such as self-assembly and complem

269 However, complex aspects of molecular recognition-such as protein flexibility or the

270 eptide foldamers and gives new insights into molecular recognition, supramolecular design, and ration

271 ions with polysaccharides and polysaccharide molecular recognition systems coordinate the principal r

272 xplore the fundamental principles underlying molecular recognition systems, which we consider in term

273 detection of cancer cells through important molecular recognition target such as sialic acid is sign

274 ta-caryophyllene is among the most difficult molecular recognition tasks.

275 Knowledge of the forces associated with the molecular recognition that governs Trx-protein interacti

276 Molecular recognition--the ability of a molecular machin

277 hydrophobic pocket exclusively via specific molecular recognition; the contact interface is dominate

278 ch repeat domains (LRR) as proposed sites of molecular recognition, though limited biochemical eviden

279 substitution-inert complexes is achieved by molecular recognition through minor groove spanning and

280 cribe the extension of radical-pairing-based molecular recognition to a larger, square-shaped diradic

281 d biomimetic transformations, and the use of molecular recognition to control reaction selectivity.

282 Molecular recognition to preorganize noncovalently polym

283 ilize defined sequences and monomer-specific molecular recognition to store and transfer information.

284 These events range from protein folding and molecular recognition to the formation of hierarchical s

285 s are the conventional and ideal choice as a molecular recognition tool for many applications, aptame

286 synthetic chemistry, in conjunction with the molecular recognition toolkit pioneered by the field of

287 oth a calix[4]arene moiety which serves as a molecular recognition unit and an activity regulator com

288 se layer of polymer chains that terminate in molecular recognition units capable of programmed supram

289 espective adhesive interactions between LHRH molecular recognition units on the prodigiosin (PGS) and

290 The ability for molecular recognition was evaluated with the well-known

291 ral factors underlying this highly selective molecular recognition, we have used solid-phase peptide

292 s with the conformational selection model of molecular recognition, which assumes such pre-existing c

293 fic sandwich-type detection due to specific, molecular recognition, while unbound beads move along pa

294 new charge transport mechanism and specific molecular recognition with biomolecules.

295 However, molecular recognition with hexaphyrins has been underexp

296 results provide unprecedented insights into molecular recognition with hexaphyrins, paving the way t

297 how that rhodium(II) metallopeptides combine molecular recognition with promiscuous catalytic activit

298 The SCNPs utilise molecular recognition with surface-immobilised proteins

299 nt secondary structure are often involved in molecular recognition, with the structure being stabiliz

300 fferent levels of biological organization-in molecular recognition, within a single regulatory networ