ライフサイエンスコーパス: molecular ruler

1 rentiation and may, therefore, function as a molecular ruler.

2 e) complex attached to the gold surface as a molecular ruler.

3 the nanoscale architecture of FAs, akin to a molecular ruler.

4 labeled molecules and quantum dots to act as molecular rulers.

5 gonucleotides (dT) with varying lengths as a molecular ruler and also as the substrate, we have deter

6 nt organisation suggesting that it acts as a molecular ruler and template, but the exact axial dispos

7 st Dicers establishes a paradigm for natural molecular rulers and imparts substrate preferences with

8 Nanoplasmonic molecular rulers and integrated photoacoustic-phototherm

9 port the role of nebulin as a thin filament "molecular ruler" and provide a molecular basis for study

10 that are important for, e.g., their use as "molecular rulers" and "molecular scaffolds".

11 We describe herein a series of "molecular rulers" and their use in assessing the topolog

12 Thus, a crosstalk between molecular 'rulers' and 'clocks' licenses mitotic exit on

13 ized solvatochromic surfactants that act as 'molecular rulers' and resonance-enhanced second-harmonic

14 This setup acts as a molecular ruler at layer resolution-we determined Tau fi

15 undamental problem by extending the standard molecular ruler based on Forster resonance energy transf

16 This DNA substrate can be likened to a molecular ruler because it consists of a 235-bp double-s

17 Ultimately, our long-range SERS molecular rulers can be an important step toward underst

18 A molecular-ruler clone panel for each chromosome arm was

19 the 3'-CCA end by the THUMP domain yields a molecular ruler defining the specificity for U8 thiolati

20 Here TFIIH serves as a molecular ruler, defining the DNA bubble size and precis

21 sted with double-stranded DNA, the canonical molecular ruler, demonstrating their performance for sin

22 -fCzrA), 2 (10L-fCzrA), or 3 (15L-fCzrA), as molecular rulers designed to restrict any quaternary str

23 of the polymer extension process, whereas a "molecular ruler" determines length by measurement agains

24 lved remain unresolved, it is proposed that "molecular rulers" dictate the lengths of the actin filam

25 vide a mechanistic basis for the action of a molecular ruler element in nucleosome spacing.

26 A molecular ruler, FliK, controls the length of the flagel

27 tacrine affinities thus provided a sensitive molecular ruler for assigning the binding locations of t

28 er it unlikely that FliK is functioning as a molecular ruler for determining hook length and conclude

29 ion of experiments on polyproline, used as a molecular ruler for FRET experiments, namely the potenti

30 Titin has been suggested to act as a molecular ruler for the precise assembly of thick filame

31 ve Ran and chromatin position, function as a molecular ruler for the recruitment and localization of

32 e suggests that the coiled-coil CRs act as a molecular ruler for the separation between two recognize

33 lecule FRET (smFRET) has long been used as a molecular ruler for the study of biology on the nanoscal

34 with capsaicin, these ligands form a set of molecular rulers for investigating ligand-induced confor

35 s a universal length control mechanism using molecular rulers for T3S systems.

36 ng a broad range of substrates, which act as molecular rulers for the substrate channel in MCR.

37 We present evidence that the distinctive "molecular ruler" function of the ATP-dependent single st

38 E-Tmod/TM5 complex may function as a "molecular ruler" generating actin protofilaments of appr

39 ken together, these data do not support the "molecular ruler hypotheses".

40 lex of FTase with FPP leads us to suggest a "molecular ruler" hypothesis for isoprenoid substrate spe

41 does not generate peptides according to the "molecular ruler" hypothesis, and 2) other peptidases mus

42 y rigidify the substrate and function as the molecular ruler in determining the site of cleavage.

43 The use of the rigid ligands as molecular rulers in conjunction with double-mutant cycle

44 The use of the rigid dTC analogs as "molecular rulers" in conjunction with double-mutant cycl

45 ncremental fashion using rigid oligoproline "molecular rulers" in the 18-45 A length range.

46 e Salmonella flagellar hook, uses a secreted molecular ruler, InvJ, to determine needle length.

47 d specifies the 5'-splice site and that this molecular ruler is conserved among a subclass of group I

48 ending the range of optical based methods in molecular rulers is an important leap forward for biophy

49 lthough on the surface, nebulin looks like a molecular ruler, it may be playing a more complex role i

50 A molecular ruler mechanism based on observed water positi

51 ementary mutational analysis in sGC reveal a molecular ruler mechanism that allows sGC to favor NO ov

52 Its "molecular ruler" mechanism involves binding the hydropho

53 We propose a two-checkpoint molecular ruler model for tRNA decoding in which the inf

54 e explained by either a molecular clock or a molecular ruler model.

55 ent of the active sites (as proposed by the "molecular ruler" model); instead, we propose that proteo

56 filaments are likely specified by the giant "molecular ruler" nebulin, which spans the length of the

57 The "molecular ruler" of AdnAB is regulated by ATP, which eli

58 of Na(+)/H(+) antiporters (exchangers), as a molecular ruler, our studies reveal that pendrin, a clin

59 urfactants have the potential to function as molecular rulers: probes of molecular-scale variation in

60 ts in septin filaments and thus serves as a "molecular ruler." Second, the method yields little or no

61 by scaled-particle adsorption theory, these molecular rulers show how membrane-bending elasticity ca

62 n nebulin has been proposed to function as a molecular ruler specifying filament lengths.

63 anometal surface energy transfer (NSET) is a molecular ruler technique that has been utilized to opti

64 Thus, Dicer itself is a molecular ruler that recognizes dsRNA and cleaves a spec

65 rates, illustrating that RhlA functions as a molecular ruler that selectively extracts 10-carbon inte

66 hook-length control in which FliK acts as a molecular ruler that takes measurements of rod-hook leng

67 lex DNA molecule (30 bp) was used as a 10-nm molecular ruler to confirm the validity of the method.

68 The DNA can also serve as a molecular ruler to control the distance-dependent synerg

69 ator by a coiled-coil structure that forms a molecular ruler to determine product length.

70 lution has the potential to act as a precise molecular ruler to determine the positions of specific c

71 mechanism by which Cas1-Cas2 functions as a molecular ruler to dictate the sequence architecture of

72 apable of using the size of naked dsDNA as a molecular ruler to distinguish self from nonself.

73 ethiosulfonate modifiers, creating a precise molecular ruler to estimate the distance between a a1B3y

74 th the experimental values and established a molecular ruler to explore steric and magnetic environme

75 ght act after initial substrate binding as a Molecular Ruler to form a protein-DNA complex with the s

76 thesize that a Ran(GTP) gradient serves as a molecular ruler to interpret the asymmetric position of

77 In these experiments, DNA was used as a molecular ruler to measure the average distance (d(blob)

78 Two dsRBDs form a molecular ruler to measure the stem length between the t

79 al muscle that has been proposed to act as a molecular ruler to specify the thin filament lengths cha

80 ri-crystal structure, using DNA origami as a molecular ruler to titrate spacing between TCR and CD4 w

81 ized nonpolar thymidine and uracil mimics as molecular rulers to probe the active site steric constra

82 ine tracts in a polycytosine chain served as molecular rulers to probe the distance dependence of the

83 We used DNA as a "molecular ruler" to measure intra-epitope distances on v

84 arrow with a fixed terminus, it can act as a molecular 'ruler' to select alkyl chains of a particular

85 e extremely stable Nup107-160 structure as a molecular ruler, we defined the practical labeling radiu

86 tein containing a characteristic coiled-coil molecular ruler, which determines glycan chain length.

87 s that the A29 interaction sets one end of a molecular ruler whose other end specifies the 5'-splice

88 for values <70 nm, which enables the use of molecular rulers with known thicknesses (such as self-as

89 gy was found between the FliK proteins and a molecular ruler, YscP, from a virulence-associated type-