ライフサイエンスコーパス: monoamine oxidase A

1 R antagonist or after incubation with MAO-A (monoamine oxidase-A).

2 e include potent and selective inhibitors of monoamine oxidase A.

3 ents and four Sp1-binding sites in the human monoamine oxidase A 2-kb promoter.

4 Low monoamine oxidase A activity increased risk for conduct

5 NIRKO mice also exhibit increased levels of monoamine oxidase A and B (MAO A and B) leading to incre

6 In a screening for potential monoamine oxidase A and B inhibition ciproxifan showed e

7 the central nervous system which is rich in monoamine oxidase A and B.

8 ted high selectivity (>160x) against related monoamine oxidase A and B.

9 Cloning of MAO (monoamine oxidase) A and B has demonstrated unequivocall

10 eas was similarly modulated by inhibition of monoamine oxidase-A and was reduced in animals with indu

11 tion and activity of recombinant human liver monoamine oxidases A and B (MAO A and B).

12 dent amine oxidizing enzymes including human monoamine oxidases A and B (MAO A and MAO B) show aromat

13 The monoamine oxidases A and B (MAO-A and -B) genes, which a

14 Monoamine oxidases A and B (MAO-A and MAO-B) are enzymes

15 rs with notable selectivity toward SSAO over monoamine oxidases A and B (MAO-A and MAO-B).

16 cture (which also has inhibitory activity at monoamine oxidases A and B and at the serotonin and nore

17 d binding to the norepinephrine transporter, monoamine oxidase A, and alpha2-adrenoceptors were measu

18 ty towards acetyl/butyrylcholinesterases and monoamine oxidases A/B as well as the histamine H3 recep

19 The degree of inhibition of monoamine oxidase A by R1 correlated with the level of R

20 ors, the sequences of three Sp1 sites in the monoamine oxidase A core promoter were used in the yeast

21 ryptophan hydroxylase 1 and a suppression of monoamine oxidase A expression (enzymes responsible for

22 gnificant association between high levels of monoamine oxidase A expression and poorly differentiated

23 e shown that the Sp1 family is important for monoamine oxidase A expression.

24 Monoamine oxidase A gene (MAOA) has earned the nickname

25 his study shows that glucocorticoid enhances monoamine oxidase A gene expression by 1) regulation of

26 Studies on the regulation of monoamine oxidase A gene expression have shown that the

27 s that R1 is a novel repressor that inhibits monoamine oxidase A gene expression.

28 e evidence indicates that the low-expressing monoamine oxidase A genotype specifically predisposes to

29 Human monoamine oxidase A (hMAOA) is considered to be unique a

30 ve of either serotonin uptake transporter or monoamine oxidase-A inhibition, as well as slight increa

31 tor), SERT RNA-interference, and iproniazid (monoamine oxidase-A inhibitor), blocked 5-HT-induced S10

32 the current study, we used a genetic model (monoamine oxidase-A knockout mouse) in which brain 5-HT

33 , high serotonin transporter levels, and low monoamine oxidase A levels, suggesting that low intersti

34 The monoamine oxidase A locus (MAOA) at Xp11 was considered

35 quencies of a microsatellite and RFLP at the monoamine oxidase A locus in bipolar affective disorder

36 near the covalent 8alpha-S-cysteinyl FAD in monoamine oxidase A (MAO A) and to test the suggestion t

37 Monoamine oxidase A (MAO A) degrades serotonin, norepine

38 The FAD binding site of human liver monoamine oxidase A (MAO A) has been investigated by mut

39 Mice deficient in monoamine oxidase A (MAO A) have elevated brain levels o

40 ly shown that the serotonin-degrading enzyme monoamine oxidase A (MAO A) is an important source of hy

41 Inhibition of monoamine oxidase A (MAO A) is believed to cause antidep

42 Monoamine oxidase A (MAO A) is the critical enzyme to de

43 Smokers have reduced levels of brain monoamine oxidase A (MAO A) leading to speculation that

44 A spontaneous monoamine oxidase A (MAO A) mutation (A863T) in exon 8 i

45 Monoamine oxidase A (MAO A) plays a central role in the

46 Monoamine oxidase A (MAO A) plays a role in glioma devel

47 The interaction of recombinant human liver monoamine oxidase A (MAO A) with a series of phenethylam

48 The genetic deletion of monoamine oxidase A (MAO A), an enzyme that breaks down

49 Monoamine oxidase A (MAO A), encoded by the X chromosome

50 Converging evidence shows that monoamine oxidase A (MAO A), the key enzyme catalyzing s

51 However, it has been reported that monoamine oxidase A (MAO A, a major neurotransmitter-deg

52 by increased blood glucocorticoids and brain monoamine oxidase A (MAO A, which degrades monoamine neu

53 Monoamine oxidase A (MAO(A)) knockout mice have highly e

54 The use of selective inhibitors of monoamine oxidase A (MAO-A) and B (MAO-B) holds a therap

55 or associated with deficient function of the monoamine oxidase A (MAO-A) enzyme.

56 compared to linezolid but suffer from potent monoamine oxidase A (MAO-A) inhibition and low solubilit

57 Monoamine oxidase A (MAO-A) is a key enzyme in the catab

58 Monoamine oxidase A (MAO-A) is a key regulator of seroto

59 Monoamine oxidase A (MAO-A) is a major enzyme responsibl

60 Monoamine oxidase A (MAO-A) is an enzyme best known for

61 Monoamine oxidase A (MAO-A) is an important brain enzyme

62 Monoamine oxidase A (MAO-A) is an important enzyme on th

63 o counter the effects of the 40% increase in monoamine oxidase A (MAO-A) levels that occurs during PP

64 One such biological abnormality is elevated monoamine oxidase A (MAO-A) levels, which occurs in the

65 hydroxyphenylglycolaldehyde (DOPEGAL) is the monoamine oxidase A (MAO-A) metabolite of norepinephrine

66 ylglycolaldehyde (DOPEGAL) is the neurotoxic monoamine oxidase A (MAO-A) metabolite of norepinephrine

67 ating transcription of the gene encoding the monoamine oxidase A (MAO-A) to reduce serotonin levels i

68 We found that monoamine oxidase A (MAO-A) was the most significantly u

69 As PI-2014 displayed off-target binding to monoamine oxidase A (MAO-A), a new lead with improved bi

70 SIRT1 did so by increasing expression of monoamine oxidase A (MAO-A), a SIRT1 target that reduces

71 zolid (marketed as Zyvox), are inhibitors of monoamine oxidase A (MAO-A), which presents an undesired

72 ompanied by an increase in the expression of monoamine oxidase-A (MAO-A) and MAO-B in the lateral OFC

73 Monoamine oxidase-A (MAO-A) is a treatment target in neu

74 Here we report that high expression of monoamine oxidase-A (MAO-A) is associated with positive

75 Monoamine oxidase-A (MAO-A), a key brain enzyme which me

76 cluding catechol-O-methyltransferase (COMT), monoamine oxidase-A (MAO-A), vesicular monoamine transpo

77 study examined how the mitochondrial enzyme monoamine oxidase-A (MAO-A), which produces hydrogen per

78 affinity to recombinant rat cerebral cortex monoamine oxidases A (MAO A) and B (MAO B) determined.

79 Monoamine oxidase A (MAOA) activity was associated with

80 region contains, among others, the genes for monoamine oxidase A (MAOA) and B (MAOB), which are invol

81 We examined the impact of constitutive monoamine oxidase A (MAOA) deficiency in mice on nicotin

82 Mice lacking monoamine oxidase A (MAOA) display high levels of brain

83 r adipose NE levels that stem from decreased monoamine oxidase A (MAOA) expression and NE clearance b

84 A functional promoter polymorphism in the monoamine oxidase A (MAOA) gene has been implicated as a

85 g RNA (lncRNA), acting as a regulator of the monoamine oxidase A (MAOA) gene in the brain, and named

86 examining allelic variation in the X-linked monoamine oxidase A (MAOA) gene, previously associated w

87 esonance imaging and genetic analysis of the monoamine oxidase A (MAOA) gene, we investigated how str

88 olymorphisms in dopamine receptor (DRD4) and monoamine oxidase A (MAOA) genes showed significant asso

89 (5HT) and the monoamine-metabolizing enzyme monoamine oxidase A (MAOA) have been repeatedly implicat

90 y, we identify for the first time a role for monoamine oxidase A (MAOA) in NPC.

91 Here, we report that monoamine oxidase A (MAOA) is a clinically and functiona

92 We report that monoamine oxidase A (MAOA) is a clinically and functiona

93 Monoamine oxidase A (MAOA) is a mitochondrial enzyme tha

94 The rs1137070 polymorphism of monoamine oxidase A (MAOA) is associated with alcoholism

95 ic mouse line in which the gene that encodes monoamine oxidase A (MAOA) is disrupted, resulting in ex

96 ohorts of Finnish prisoners, revealed that a monoamine oxidase A (MAOA) low-activity genotype (contri

97 Pharmacologic blockade of monoamine oxidase A (MAOA) or serotonin transporter (5-H

98 g growth differentiation factor-3 (GDF3) and monoamine oxidase A (MAOA) that is known to degrade nora

99 ing the neurotransmitter-metabolizing enzyme monoamine oxidase A (MAOA) was found to moderate the eff

100 6 member 2 (SLC6A2), an NE transporter, and monoamine oxidase A (MAOA), a degradation enzyme.

101 Monoamine oxidase A (MAOA), a mitochondria-bound enzyme,

102 Here, we show that upregulation of monoamine oxidase A (MAOA), a mitochondrial enzyme that

103 cancer (PCa) exhibit increased expression of monoamine oxidase A (MAOA), a mitochondrial enzyme that

104 Mice deficient in monoamine oxidase A (MAOA), an enzyme that metabolizes m

105 polymorphisms affecting transcription level: monoamine oxidase A (MAOA), neuropeptide Y (NPY), endoth

106 Polymorphisms in the monoamine oxidase A (MAOA-LPR) and serotonin receptor 2A

107 hydroxyphenylglycolaldehyde (DOPEGAL) is the monoamine oxidase A metabolite of norepinephrine (NE) an

108 hydroxyphenylglycolaldehyde (DOPEGAL) is the monoamine oxidase A metabolite of norepinephrine and epi

109 3,4-Dihydroxyphenylglycolaldehyde is the monoamine oxidase-A metabolite of two catecholamine neur

110 luded those involved in cellular metabolism: monoamine oxidase-A, mitochondrial-A synthase complex, a

111 (p < 0.05) increases in adenosine deaminase, monoamine oxidase-A, nucleotides tri-phosphatase, 5'-nuc

112 re was a main effect of adversity but not of monoamine oxidase A on risk for conduct disorder.

113 tistically significant effects on binding to monoamine oxidase A or to the norepinephrine transporter

114 R1 was also found to repress monoamine oxidase A promoter activity within a natural c

115 toma cell line, SK-N-BE (2)-C, inhibited the monoamine oxidase A promoter and enzymatic activity.

116 R1 also bound directly to the natural monoamine oxidase A promoter in vivo as shown by chromat

117 ith clorgyline, an irreversible inhibitor of monoamine oxidase A, restored hippocampal noradrenaline

118 A deficiency in monoamine oxidase A results in aggressive behavior in bo

119 rine secretion; P < 0.01), with no effect on monoamine oxidase A (serotonin catabolism), serotonin re

120 These carbamates are selective monoamine oxidase A substrates.

121 -serotonin and increased after inhibition of monoamine oxidase-A, the main enzyme responsible for ser

122 the activities of acetylcholine esterase and monoamine oxidase-A which changed by Pb toxicity.