ライフサイエンスコーパス: monopolar

1 UNC-6 or SLT-1 causes the neurons to become monopolar.

2 bition of aurora B or Eg5 kinesin, underwent monopolar anaphase on time and without additional interv

3 om cultured cells also leads to formation of monopolar and abnormal spindles and centrosome loss.

4 reas klp-18(-) and mei-1(-) mutants assemble monopolar and apolar spindles, respectively.

5 creased levels of nuclear envelope proteins, monopolar and asymmetric spindles, and chromosomes that

6 se the effects of NuSAP and Kid depletion in monopolar and bipolar cells with or without kinetochore

7 - termed 'new-end take-off' (NETO) - between monopolar and bipolar growth mid-way through the cell cy

8 icrotubules during cytokinesis in cells with monopolar and bipolar spindles shows that a subpopulatio

9 Finally, by combination of the monopolar and dipolar scattering effects associated with

10 coding gene merry-go-round (mgr), leading to monopolar and disorganized mitotic spindles containing f

11 The monopolar and half-skyrmion pseudospin textures are meas

12 ationship between the observed propensity of monopolar and multipolar defects and the geometry of RFs

13 rmal spindle development, as we observe both monopolar and multipolar spindles in Eg5 transgenic mice

14 It also induced the formation of monopolar and multipolar spindles in mitotic cells.

15 r longer periods increasingly show tripolar, monopolar and other spindle defects, and give rise to em

16 forced-choice adaptive procedure under both monopolar and quadrupolar stimulation.

17 efects and aberrant MT structures, including monopolar and small spindles.

18 ese conditions are not met: 1) collapsed, 2) monopolar, and 3) multipolar spindles, and the computati

19 ytes that do divide are either diminutive or monopolar, and do not make contact with the fusome.

20 der ultrasound guidance using a novel LeVeen monopolar array needle electrode and an RF 2000 generato

21 pole body (SPB) assembles a long and stable monopolar array of nuclear microtubules that spans the e

22 t depletion of Pak1/2 allows cells to escape monopolar arrest by Eg5 inhibition, highlighting the pot

23 Monopolar attached sister centromeres are resolved to bi

24 osed on sister kinetochores that facilitates monopolar attachment to the MI spindle.

25 es at MI, and univalents constrained to form monopolar attachments should be inherently unstable and

26 er mechanosensitive mechanism to correct the monopolar attachments.

27 copy reveals that intercalating cells extend monopolar, basolateral protrusions in their direction of

28 We performed bench-top validation of monopolar, bipolar, and multipolar stimulation regimes a

29 ough reorientation of increasingly spin-like monopolar bound states.

30 OBJECTIVE(S): The monopolar "Bovie" is used in virtually every laparoscopi

31 the right and left ventricles using a focal monopolar catheter.

32 oduce one daughter cell that develops into a monopolar cell and one daughter that develops into a bip

33 tes, and the Deltapom1 mutation brings about monopolar cell growth.

34 Large type 2 monopolar cells (L2) and type 1 amacrine cells, which in

35 arrying out spatial summation are the lamina monopolar cells (LMCs) of the first visual processing ar

36 L2 monopolar cells ending in the medulla are accompanied by

37 with cells of various types, including large monopolar cells, but close apposition to photoreceptor t

38 Locust lamina monopolar cells, L1 and L2, were the main targets of the

39 dly, cytokinesis occurs at high frequency in monopolar cells.

40 nal net, is predicted to support states with monopolar charge order at entropies below that of the pr

41 ltiple functions, including the promotion of monopolar chromosome attachment in the first division.

42 kinetochore functions that are essential for monopolar chromosomes to establish bipolar connections a

43 We stimulated via 6-contact CIs in monopolar configuration with symmetric, biphasic pulses

44 rains from 128 to 300 pulses per second in a monopolar configuration.

45 Four ablations, two bipolar and two monopolar (control probe), were made in each of five liv

46 icrotubules promote symmetry breaking during monopolar cytokinesis and regional specialization of the

47 We employed monopolar cytokinesis to reveal that midzone plus ends a

48 ail to form a cleavage furrow [3] and during monopolar cytokinesis when myosin contractility is block

49 ed to the distal ends of microtubules during monopolar cytokinesis, depletion of PRC1 and KIF4A displ

50 n in HeLa cells undergoing drug-synchronized monopolar cytokinesis.

51 e array, we sought to clarify their roles in monopolar cytokinesis.

52 The monopolar Deltapom1 mutant fails to eliminate Rga4 from

53 The monopolar device demonstrated the expected inverse assoc

54 a-phosphatidylcholine (DPPC), a conventional monopolar diester lipid.

55 e main phase transitions of saturated diacyl monopolar diester lipids.

56 o observed in bilayers composed of saturated monopolar diester phosphatidylcholines at their main pha

57 result opposite that previously obtained on monopolar diester phospholipids.

58 4 from the nongrowing cell end, resulting in monopolar distribution of GTP-Cdc42 to the growing cell

59 on achieves better frequency resolution than monopolar electrical stimulation.

60 te, which is traditionally performed using a monopolar electrocautery system resulting in the possibi

61 e performance of acquiring EHG signals using monopolar electrode and three types of Laplacian concent

62 se challenges, we propose a novel blade-type monopolar electrode employing dielectric heating as the

63 the present study, we tested the effects of monopolar electrode stimulation and low-duty cycle AC st

64 The suppression generated by the monopolar electrode was localized to a region surroundin

65 g the ring, which we define, hereafter, as a monopolar electrode, ME.

66 ts were treated with PFA using an epicardial monopolar electrode.

67 mong the various electrosurgical modalities, monopolar electrodes have become indispensable in open s

68 sign of the experiment involved placement of monopolar electrodes into the medial hypothalamus from w

69 Conventional monopolar electrodes operate at high temperatures (excee

70 either intracochlear bipolar or round window monopolar electrodes.

71 ed if an operative event includes the use of monopolar electrosurgery ('Bovie') or significant fluid

72 thods of electrosurgical dissection, such as monopolar electrosurgery and CO(2) laser, showed spectra

73 pid region of m/z 600-1000 compared with the monopolar electrosurgical and CO(2) laser-generated spec

74 In contrast, monopolar electrosurgical and laser spectra demonstrated

75 r lesions were significantly deeper than the monopolar epicardial lesions.

76 Unlike more common monopolar, ester-linked phospholipids, C20BAS-PC exhibit

77 r results suggest that, in contrast to other monopolar-growing mutants, the monopolar phenotype of th

78 is a critical regulator to ensure persistent monopolar growth during S phase.

79 nt polarity factor tea1p, which prepares for monopolar growth initiation and later switching to bipol

80 yeast and their unusual localization in the monopolar growth mutant orb2-34, which carries a non-let

81 orb2-34 allele of shk1 exhibit a pattern of monopolar growth similar to that observed in tea1 Delta

82 The deltawsh3 mutant shows monopolar growth with abnormal Tea1 aggregate at the non

83 BEST PRACTICE ADVICE 4: Monopolar hemostatic forceps with low-voltage coagulatio

84 regulates the mitotic exit network (MEN) and monopolar homolog orientation in meiosis I.

85 or input, whereas amacrine cells are usually monopolar inhibitory interneurons with synapses almost e

86 ver, as spindles assemble through a perilous monopolar intermediate.

87 We identified a monopolar interneuron in the mouse retina that resembles

88 These glutamatergic monopolar interneurons (GluMIs) do not receive direct ph

89 a new treatment modality which replaces the monopolar IRE pulses with a burst of bipolar pulses, has

90 etraploids have a high incidence of syntelic/monopolar kinetochore attachments to the spindle pole.

91 cture, leading us to propose a model for how monopolar kinetochore-spindle attachments may contribute

92 Moreover, reducing KLP-7 function in monopolar klp-18(-) mutants often restored spindle bipol

93 into 11 major subgroups representing lamina monopolar (L), medulla intrinsic (Mi, Mt), bushy T (T),

94 ess was obtained successfully and epicardial monopolar lesions had a mean length, width, and depth of

95 pends on the hydrocarbon chain length of the monopolar lipid and the bolalipid concentration.

96 mismatch between hydrophobic regions of the monopolar lipid hydrocarbon chains and the membrane-span

97 phobic thicknesses of the pure bolalipid and monopolar lipid layers.

98 In the monopolar lipid-rich phase, bolalipids are the minor com

99 riving force for the phase separation in the monopolar lipid/bolalipid mixture is the packing mismatc

100 ipid layer that is a mixture of conventional monopolar lipids and C20 bipolar bolalipids was studied

101 s the length of the hydrocarbon chain of the monopolar lipids, was probed.

102 tightly packed membranes compared to typical monopolar lipids.

103 h: after cell division, they grow first in a monopolar manner at the old end, and in G2 phase, initia

104 elta and bud6Delta cells generally grow in a monopolar manner but exhibit different growth patterns.

105 esoderm explants, neural plate cells express monopolar medially directed motility and notoplate cells

106 absence of the notochord, the characteristic monopolar, medially directed behavior occurred, but only

107 nd determine whether it alone can induce the monopolar, medially directed cell behavior.

108 overlying notoplate were found to induce the monopolar, medially directed protrusive activity of deep

109 mesoderm, lateral neural plate cells show a monopolar, medially directed protrusive activity.

110 r3p, meiotic cells are blocked with prophase monopolar microtubule arrays and incomplete synaptonemal

111 Inhibition of Eg5 resulted in monopolar microtubule arrays emanating from chromatin be

112 Furthermore, we show that the formation of monopolar microtubule arrays in human cell extracts does

113 ere above a ground plane surrounding a small monopolar microwave emitter in order to maximise its rad

114 calizes to actin cables in a gap between the monopolar midzone and the furrow-like cortex, suggesting

115 -dense material and resemble similar foci in monopolar midzones in cells.

116 lso compromised, mps1-1 cells proceed with a monopolar mitosis and rapidly lose viability.

117 early in SPB duplication and proceed through monopolar mitosis with lethal consequences.

118 ter forced mitotic exit, the cytoskeleton of monopolar mitotic cells is initially radially symmetric

119 lity, on single fibers, results in increased monopolar mitotic defects, while multipolar defects beco

120 at of paclitaxel and caused the formation of monopolar mitotic figures identical to those produced in

121 cut12.1 mutants form a monopolar mitotic spindle, chromosome segregation fails,

122 First, monopolar mitotic spindles form.

123 ulses-per-second pulse trains, stimulated in monopolar mode (i.e. the clinical default), and at diffe

124 o the skin, either non- or invasively, via a monopolar mode that utilizes an active electrode and a g

125 es as well as, in some instances, the normal monopolar morphology of the P cell becoming multipolar.

126 triggered (RT) bipolar (BP) sequence, (b) RT monopolar (MP) sequence, (c) free-breathing (FB) BP sequ

127 el partial tripolar (pTP) and (b) 14-channel monopolar (MP), and four variable-channel programs, deri

128 becomes fragmented at meiosis I, leading to monopolar, multiple, and mislocalized spindles.

129 dy (SPB), which becomes enlarged as in other monopolar mutants.

130 opy direction is 3, which translates into 12 monopolar needle insertions (i.e. 3 directions x 4 elect

131 ct with the anisotropic material, e.g. using monopolar needles.

132 al circuits that includes the cholinergic L2 monopolar neurons from the lamina.

133 Parvalbumin neurons were mainly round monopolar neurons, especially common in the superficial

134 as control cells had long, radially oriented monopolar or bipolar neurites.

135 We found that Eg5 inhibition led to either monopolar or bipolar spindle formation, depending on whe

136 Centres used their usual TURP procedure (monopolar or bipolar).

137 Kif2b-deficient cells assemble monopolar or disorganized spindles.

138 ing the relative stability of bipolar versus monopolar organization.

139 absence of PP4, chromosomes exhibit extended monopolar orientation after NEBD and subsequently mis-se

140 re assembly and recovery of chromosomes from monopolar orientation to significant bi-orientation.

141 the orb2-34 allele of shk1, Rga8 exhibits a monopolar pattern of localization, providing evidence th

142 hanism of the transition from a dipolar to a monopolar pattern remain unknown.

143 ess the feasibility and safety of repetitive monopolar PFA applications to ablate (1) intracavitary p

144 ter was used to deliver proprietary biphasic monopolar PFA applications to swine ventricles under gen

145 reedom from atrial arrhythmia outcomes using monopolar PFA delivered through 3 commercial, contact fo

146 ce-tip catheter was used to deliver biphasic monopolar PFA to swine ventricles under general anesthes

147 We show that the cut12.1 monopolar phenotype arises from a failure to activate an

148 rast to other monopolar-growing mutants, the monopolar phenotype of the orb2-34 mutant might not be d

149 4 in the Deltapom1 mutant contributes to its monopolar phenotype.

150 expansion coefficients are within 20% of the monopolar phospholipid, DLPC.

151 figuration and in ventricular tissue using a monopolar probe configuration, analyzing how waveforms a

152 d the dorsal midline using medially directed monopolar protrusions.

153 dodermal cells within these explants display monopolar protrusive activity and radially intercalate d

154 lateral edge of these explants restores the monopolar protrusive activity over the entire extent of

155 RE uses ultra-short duration, high-intensity monopolar pulsed electric fields to permanently disrupt

156 s which uses short (50-100 mus) high voltage monopolar pulses to disrupt the membranes of cells withi

157 ritic structures, four types of SCN neurons (monopolar, radial, simple bipolar and curly bipolar) wer

158 Monopolar radiofrequency energy was delivered to a lapar

159 discharge pattern (less than 1 ms apart) in monopolar recordings from electrodes placed in the corte

160 Each animal was implanted with three monopolar/referential electrodes chosen among the follow

161 quantitatively assessed through standardized monopolar reviews and mapped into standard space.

162 Randomised, double-blinded monopolar reviews determining SID thresholds were conduc

163 Monopolar reviews were conducted in 14 essential tremor

164 , tumors were treated with (a) conventional, monopolar RF (250 mA +/- 25 [SD] at 70 degrees C +/- 1 f

165 o four experimental groups: (a) conventional monopolar RF (70 degrees C for 5 minutes) alone, (b) lip

166 ors each were treated with (a) conventional, monopolar RF (96 mA +/- 28; 70 degrees C for 5 minutes);

167 , tumors were treated with (a) conventional, monopolar RF (mean, 250 mA +/- 25 [SD] at 70 degrees C +

168 Conclusion Unlike monopolar RF ablation, change in portal vein flow rates

169 o four experimental groups: (a) conventional monopolar RF alone (70 degrees C for 5 min), (b) IV lipo

170 A 17-gauge monopolar RF probe was inserted into the pancreas with M

171 to a thin bolalipid-rich layer and a thicker monopolar-rich layer.

172 ard current showed four types of morphology: monopolar, simple bipolar, curly bipolar and radial shap

173 py and computational alignment, we find that monopolar sperm asters do not show evidence for flux, pa

174 We found that the checkpoint protein kinase monopolar spindle 1 (Mps1) directly bound to Ndc80C thro

175 Activation of this pathway by pulsed monopolar spindle 1 (MPS1) inhibitor treatment, which po

176 The dual-specificity protein kinase monopolar spindle 1 (Mps1) is a central component of the

177 Monopolar spindle 1 (Mps1) is a dual-specificity protein

178 Monopolar spindle 1 (Mps1) is essential for the spindle

179 Inhibition of monopolar spindle 1 (MPS1) kinase represents a novel app

180 e checkpoint as a consequence of stabilizing monopolar spindle 1 (Mps1) levels in human melanoma cell

181 Monopolar spindle 1 (MPS1) plays a central role in the t

182 nked by Lox mutation was introduced into the monopolar spindle 1 (Mps1) spindle-assembly checkpoint g

183 is monitored by the serine/threonine kinase monopolar spindle 1 (MPS1).

184 Monopolar spindle 1 (Mps1/TTK) is a protein kinase essen

185 Monopolar spindle 1 (Mps1; also known as TTK protein kin

186 Thr/Tyr kinase (TTK)/monopolar spindle 1 kinase (Mps-1) is a kinase of the sp

187 the proper localization of the kinase Mps1 (monopolar spindle 1) is critical to both these processes

188 spd1 (heat shock 60-kDa protein 1) and mps1 (monopolar spindle 1), were up-regulated.

189 t arrest with an intact Golgi clustered at a monopolar spindle and an active spindle assembly checkpo

190 vation results in force imbalance leading to monopolar spindle and chromosome segregation failure.

191 and microtubule severing--both contribute to monopolar spindle assembly in klp-18(-) mutants.

192 ntrast, sequester centrosomal NEK2 and mimic monopolar spindle defects induced by a dominant negative

193 bsequent gamma-tubulin sorting, resulting in monopolar spindle formation and cell cycle arrest in mei

194 Here, we use controlled monopolar spindle formation to systematically define the

195 gives partial rescue of tubulin instability, monopolar spindle formation, and loss of centrosomes, le

196 l proliferation failure, mitotic arrest, and monopolar spindle formation.

197 ntrosome separation is reduced, resulting in monopolar spindle formation.

198 e of human KSP, can cause mitotic arrest and monopolar spindle formation.

199 on and growth of microtubules and results in monopolar spindle formation.

200 ng as well as to investigate the role of the monopolar spindle in cytokinesis.

201 aused pole splaying, and when coupled with a monopolar spindle induced by depletion of the kinesin-12

202 Monopolar spindle kinase 1 (MPS1/TTK) is a key element o

203 Both mutants exhibit defective monopolar spindle microtubules that emanate from the mot

204 12], which is sufficient to drive continuous monopolar spindle motion independently of adhesive cues

205 cells and elevated Cdc25 levels suppress the monopolar spindle phenotype of cut12.1 loss of function

206 Yeast MPS1 (monopolar spindle) is required for spindle pole duplicat

207 ed open reading frame that we call MPS3 (for monopolar spindle).

208 The monopolar spindle-one-binder (Mob) family of kinase-inte

209 istinct functions mediated by members of the monopolar spindle-one-binder (MOB) family of proteins re

210 uplicate but do not separate, resulting in a monopolar spindle.

211 28 kinase activity despite the presence of a monopolar spindle.

212 PA-1 inhibits cell proliferation and induces monopolar-spindle formation in tumor cells.

213 r spindles (most ESCRT-III/VPS4 proteins) or monopolar spindles (CHMP2A or CHMP5) and causing defects

214 Mos, requires the spindle-checkpoint kinase monopolar spindles 1 (Mps1), a cyclin E-Cdk2 target that

215 Monopolar spindles accumulated as a result of defective

216 Cells overexpressing NDC1 arrest with monopolar spindles and exhibit increase-in-ploidy phenot

217 investigated the cause for the formation of monopolar spindles and found that only one of the two sp

218 spindle assembly; its suppression results in monopolar spindles and mitotic arrest.

219 haracterized by the formation of tripolar or monopolar spindles and nondisjunction of homologous chro

220 S to activate Kif2a are injected into cells, monopolar spindles are generated.

221 aneuploid cells and, in the case of aurora, monopolar spindles arising from a failure in centrosome

222 In vivo, centrosomes fail to separate and monopolar spindles assemble without Eg5 activity.

223 mps3-1 mutants arrest in mitosis with monopolar spindles at the nonpermissive temperature, sug

224 crotubules in Xenopus egg extracts remain as monopolar spindles attached to condensed chromosomes aft

225 egradable CKAP2 led to a mitotic arrest with monopolar spindles containing highly bundled microtubule

226 motor does not contribute to the genesis of monopolar spindles during allosteric inhibition of motil

227 y experiments in vitro also showed that only monopolar spindles formed in Xenopus egg extracts supple

228 vealed that only particular analogues induce monopolar spindles impairing cell division in mitosis.

229 some increase in the formation of cells with monopolar spindles in HeLa cells but not in human diploi

230 nd complete loss of BimC function results in monopolar spindles that have two spindle poles that are

231 ly 0.5 microm/min, the same rate measured in monopolar spindles that lack antiparallel MTs.

232 how, by inducing mammalian tissue cells with monopolar spindles to enter anaphase, that furrow format

233 ficient in HBXIP arrest in prometaphase with monopolar spindles whereas HBXIP overexpression causes t

234 e-depolymerizing kinesins initially produced monopolar spindles with abnormally long microtubules, bu

235 n of mitosis in Eg5 inhibitors, which induce monopolar spindles without disrupting MT dynamics, was t

236 le with large buds, a G2 content of DNA, and monopolar spindles, although this phenotype can vary dep

237 ryos caused cleavage arrest and formation of monopolar spindles, an effect previously seen in embryos

238 ingle-molecule assays, promoted formation of monopolar spindles, and led to mitotic arrest in a light

239 mitotic microtubules, high rate of transient monopolar spindles, and subsequent high rate of chromoso

240 ts from excess XKCM1 included monoastral and monopolar spindles, as well as small prometaphase-like s

241 or addition of inactive Aur-A, which lead to monopolar spindles, delays but does not block mitotic en

242 d bipolar spindles into pairs of independent monopolar spindles, demonstrating the role of sister chr

243 ss of Eg5 function leads to the formation of monopolar spindles, followed by mitotic arrest, and subs

244 kinesin Eg5 in hTPX2-depleted cells leads to monopolar spindles, indicating that Eg5 function is nece

245 SNA-1 results in daughter centriole loss and monopolar spindles, indicating that the cartwheel and SS

246 acking both TOGp and MCAK formed bipolar and monopolar spindles, indicating that TOGp and MCAK contri

247 abilizing drug paclitaxel (taxol), including monopolar spindles, or complete lack of a mitotic spindl

248 In two-cell-stage embryos harboring abnormal monopolar spindles, SPDL-1 is required to induce the SAC

249 Similarly, oocytes exhibiting monopolar spindles, via inhibition of aurora B or Eg5 ki

250 n through mitotic arrest and accumulation of monopolar spindles.

251 ll cycle progression because cells assembled monopolar spindles.

252 a SH-SY5Y cell lines is sufficient to induce monopolar spindles.

253 te when Kid is perturbed in cells containing monopolar spindles.

254 ol, arrested mammalian cells in mitosis with monopolar spindles.

255 arrest of cleavage that was associated with monopolar spindles.

256 d works by arresting cells in mitosis due to monopolar spindles.

257 d a concomitant increase in the frequency of monopolar spindles.

258 letion of Nup98 leads to formation of stable monopolar spindles.

259 sustained polarized growth; most cells have monopolar spindles.

260 For behavioral pharmacological experiments, monopolar stimulating electrodes were implanted in the m

261 Monopolar stimulating electrodes were implanted into lat

262 Monopolar stimulating electrodes were implanted into sit

263 Monopolar stimulating electrodes were implanted into the

264 In the first phase of the study, monopolar stimulating electrodes were implanted into the

265 Monopolar stimulating electrodes were placed in the midb

266 Finally, in a monopolar stimulation configuration, the differences bet

267 timulation in neocortical epilepsies and for monopolar stimulation in mesiotemporal epilepsies.

268 ll psychophysical testing was performed in a monopolar stimulation mode (MP 1 + 2).

269 l near the behavioral threshold, at least in monopolar stimulation.

270 sholds and saturation amplitudes compared to monopolar stimulation.

271 B-INCENP, led to assembly of mono-astral and monopolar structures instead of bipolar spindles.

272 Monopolar surface EMG sensors are utilized to capture pa

273 and the resecting loop are different to the monopolar system, the resection technique is very simila

274 nds of its cylindrical cells switches from a monopolar to a bipolar mode, before it ceases during mit

275 ltiple mechanisms underlying the switch from monopolar to bipolar chromosome attachment between the m

276 , a condition known to delay transition from monopolar to bipolar growth (termed NETO [new end takeof

277 Take-Off (NETO), the normal transition from monopolar to bipolar growth.

278 However, an ultrasensitive monopolar-to-bipolar transition in spindle architecture

279 rior hemostatic outcomes compared to classic monopolar transurethral resection of the prostate.

280 e dipolar pattern is projected to shift to a monopolar wetting trend in the 2040s.