ライフサイエンスコーパス: monozygotic twin

1 ange in z score from 1 to 6 mo, P = 0.008 in monozygotic twins).

2 erum anti-topo I antibody and in her healthy monozygotic twin.

3 tively diagnose if a person was conceived as monozygotic twin.

4 layed-onset generalized dystonia syndrome in monozygotic twins.

5 atypical early onset of XLRS in 3-month-old monozygotic twins.

6 ombat veterans and their non-combat-exposed, monozygotic twins.

7 , among siblings within families and between monozygotic twins.

8 similar to the concordance rate for Canadian monozygotic twins.

9 ntrolled by studying HIV-discordant pairs of monozygotic twins.

10 phenotypes in different individuals, even in monozygotic twins.

11 were closely related, including two pairs of monozygotic twins.

12 uals, including three unrelated probands and monozygotic twins.

13 ings (B, 7.43 [95% CI, 1.05 to 13.82]) among monozygotic twins.

14 ntly different in dizygotic twins but not in monozygotic twins.

15 t are highly correlated between many elderly monozygotic twins.

16 erved were only statically significant among monozygotic twins.

17 etic BMI captured differences in BMI between monozygotic twins.

18 tion microarray data from healthy adolescent monozygotic twins.

19 l lines derived from a family of parents and monozygotic twins.

20 sive assessment of diagnostically discordant monozygotic twins.

21 n, and distinctive methylation signatures in monozygotic twins.

22 ons in five individuals, including a pair of monozygotic twins.

23 ed by zygosity, which remained similar among monozygotic twins.

24 found that the correlation of scores between monozygotic twins (0.70) was more than double the dizygo

25 nificantly higher in dizygotic twins than in monozygotic twins (1.5 [1.1-2.2]) consequent on a risk f

26 We combined data from 21,792 monozygotic twins (10,896 pairs) from 11 studies to cond

27 ce) and that have high concordance rates for monozygotic twins (30-50%) and high risks to first-degre

28 an absolute 14% (95% CI, 12%-16%) higher in monozygotic twins (46%; 95% CI, 44%-48%) whose twin also

29 marker, revealing 12.51% similarity between monozygotic twins, 5.14% between dizygotic twins, and 4.

30 95% confidence interval (CI) = 1.6-83.8) for monozygotic twins; 7.4 (95% CI = 1.0-55.3) for dizygotic

31 rain as an explanation of the discordance in monozygotic twins, a proximate cause of mental disorders

32 While there is a high concordance in monozygotic twins, about half of twin pairs are discorda

33 Here, we studied a family with a pair of monozygotic twins affected by TLE and two unaffected sib

34 gival plaque microbiome of 485 dizygotic and monozygotic twins aged 5-11.

35 e suggesting that the schizophrenia-affected monozygotic twins alone experienced a time-specific and

36 tained from schizophrenia patients and their monozygotic twin and compared also to control healthy tw

37 Monozygotic twin and other epidemiologic studies indicat

38 regulates Asc pool size, affects the rate of monozygotic twinning and polycotyly.

39 describes the first example of gene-directed monozygotic twinning and shows that Asc regulates cell p

40 pisodes of middle ear effusion were 0.04 for monozygotic twins and 0.37 for dizygotic twins (P = .01)

41 confidence interval [CI] = 0.42-0.79) among monozygotic twins and 0.44 (95% CI = 0.34-0.53) among fi

42 tions were 13.2% and 47.9%, respectively, in monozygotic twins and 14.6% and 32.8%, respectively, in

43 probandwise concordance rate of SZ is 33% in monozygotic twins and 7% in dizygotic twins.

44 Studies in monozygotic twins and archived blood spots have provided

45 the sample, 634 and 2,826 were identified as monozygotic twins and dizygotic twins/siblings, respecti

46 ot only unrelated individuals but also human monozygotic twins and even inbred mice possess statistic

47 pression differences at heterozygous loci in monozygotic twins and in unrelated individuals.

48 e included Actinomyces and Capnocytophaga in monozygotic twins and Kingella in dizygotic twins.

49 y) in human ulcerative colitis, by comparing monozygotic twins and other patient cohorts.

50 ews of genotypic and phenotypic diversity in monozygotic twins and suggest that CNV analysis in pheno

51 samples collected from healthy adult female monozygotic twins and their mothers at three time points

52 tently represented in the gut microbiomes of monozygotic twins and their mothers than components for

53 enatal stress (birthweight disparity between monozygotic twins) and negatively correlated with genera

54 measured discordant gene expression between monozygotic twins, and estimated the stability of gene e

55 ular cancer in dizygotic twins compared with monozygotic twins, and in monozygotic and dizygotic twin

56 among sib pairs, parent-offspring pairs, and monozygotic twins, and we employ a slightly different de

57 or even the most heritable mental disorders, monozygotic twins are discordant at a significant rate.

58 Monozygotic twins are genetically matched and offer an a

59 Because associations among monozygotic twins are largely independent of shared gene

60 Although the genomes of monozygotic twins are practically identical, their methy

61 ears without an opportunity arising to use a monozygotic twin as a donor.

62 similar to that seen in pregnancy-discordant monozygotic twins, at 0.22 (95% CI=0.19, 0.26).

63 .95 mm Hg per change in z score, P = 0.01 in monozygotic twins; b = -1.64, P = 0.82 in dizygotic twin

64 ln mg/dL per change in z score, P = 0.31 in monozygotic twins; b = 0.79, P = 0.01 in dizygotic twins

65 The subjects were 14 pairs of monozygotic twins between the ages of 5 and 14 years old

66 c mutation from an "experiment of nature" in monozygotic twins both prevented anemia and reduced HSP9

67 Although phenotypic differences in monozygotic twins can exist, immunosuppression may be un

68 c differences between individuals, including monozygotic twins, can account for disparate phenotypes

69 Our study was conducted in a monozygotic twin cohort of adult twin pairs (n = 21) all

70 TwinsUK and the Scandinavian T2D-discordant monozygotic twin cohort, to validate the observed associ

71 By studying a monozygotic twin cohort, we found that although prior ex

72 icular disease was 14.5 (95% CI, 8.9-23) for monozygotic twins compared with 5.5 (95% CI, 3.3-8.6) fo

73 igher risk for congenital heart defect among monozygotic twins compared with dizygotic twins, and the

74 This effect was almost doubled in monozygotic twins compared with dizygotic twins, suggest

75 Associations were stronger in female monozygotic twins compared with male twins (tetrachoric

76 ggregation, a 2%-3% sibling recurrence rate, monozygotic twin concordance >20%, association with seve

77 ficiencies, as well as familial aggregation, monozygotic twin concordance >20%, lambdas > 10, purport

78 mline mutation by whole-genome sequencing of monozygotic twins concordant for ASD and their parents.

79 ne responses to "shared epitope" antigens in monozygotic twin couples shows that, despite significant

80 l lines from a family quartet of parents and monozygotic twin daughters.

81 The low concordance rate of 33% in monozygotic twins demonstrates that illness vulnerabilit

82 ithin-family design, that is, the discordant monozygotic twin design, to study reactiveness of DNA me

83 Genome-wide association studies of monozygotic twin differences are conducted through famil

84 of alcohol use disorder is substantial, but monozygotic twin discordance indicates a role for nonher

85 s were actually discounted because of a high monozygotic twin discordance rate found in studies that

86 High monozygotic twin discordance rates for common diseases s

87 e measured algorithmically for nine pairs of monozygotic twins discordant for ADHD.

88 r differential function of T cell subsets in monozygotic twins discordant for asthma that are regulat

89 Relying on a cohort of monozygotic twins discordant for asthma we sought to det

90 The study of monozygotic twins discordant for attention deficit hyper

91 In previous studies of monozygotic twins discordant for autism, more than 75% o

92 tem parameters was conducted for 22 pairs of monozygotic twins discordant for CFS and 9 healthy pairs

93 is of lymphoblastoid cell lines derived from monozygotic twins discordant for diagnosis of autism and

94 wer levels, in female (2.29) and male (2.19) monozygotic twins discordant for dSLE exposure.

95 ere statistically significantly different in monozygotic twins discordant for LBP.

96 n cousins, half siblings, full siblings, and monozygotic twins discordant for marital status were as

97 Using whole-genome sequencing of a pair of monozygotic twins discordant for MLL (also called KMT2A)

98 red gut microbial profiles in a cohort of 81 monozygotic twins discordant for MS.

99 nerated iPSC-derived cerebral organoids from monozygotic twins discordant for psychosis.

100 Studies of monozygotic twins discordant for schizophrenia may help

101 RNA sequencing of peripheral blood RNA from monozygotic twins discordant for schizophrenia, and iden

102 In the present study of monozygotic twins discordant for schizophrenia, the affe

103 We used monozygotic twins discordant for SCZ and healthy individ

104 However, in full siblings and especially monozygotic twins discordant for smoking, risk for nonaf

105 In monozygotic twins discordant for trauma exposure, we fou

106 Indeed, we have shown in fibroblasts from monozygotic twins discordant for trisomy 21 that levels

107 criptome of fetal fibroblasts from a pair of monozygotic twins discordant for trisomy 21.

108 We also confirmed an enrichment in monozygotic twin DNA methylation discordance at these lo

109 Particularly for young and healthy monozygotic twins, DNA methylation divergence, if any, m

110 gingival plaque microbiomes of dizygotic and monozygotic twins during 3 visits over 12-months.

111 ide epigenetic studies in disease-discordant monozygotic twins emphasize the power of this design to

112 hoblastoid cell lines from four members of a monozygotic twin family.

113 pared with dizygotic twin mothers but not in monozygotic twin fathers.

114 inal samples (N = 5794, 4-82 y of age, w/386 monozygotic twins, followed for up to 8.3 y w/12,088 bra

115 ced pluripotent stem cell-derived neurons of monozygotic twins from pairs discordant for schizophreni

116 method has excellent power to differentiate monozygotic twins, full sibs, parent-offspring pairs, se

117 The monozygotic twin group was a cohort of children with nar

118 ygotic twins, more significant percentage of monozygotic twins had amblyopia (P=0.004) and strabismus

119 The monozygotic twins had concordant TYR variants.

120 lity in young adults, disease discordance in monozygotic twins has been interpreted to indicate envir

121 Transplantation between monozygotic twins has been successfully performed using

122 , genetic and epigenetic differences between monozygotic twins have been described, challenging the a

123 001), and this effect was more pronounced in monozygotic twins (hazard ratio, 1.30; 95% confidence in

124 Finally, comparisons of epigenomes from monozygotic twins help dissect genetic and environmental

125 the individuals sampled were three pairs of monozygotic twins in which one twin had never smoked and

126 hors conducted a co-twin control study of 22 monozygotic twins in which one twin met criteria for CFS

127 levant for instance in the discrimination of monozygotic twin individuals in forensic applications, c

128 e to those previously reported for a pair of monozygotic twins infected with the same strain of human

129 e of MLL-rearranged acute leukemia in infant monozygotic twins is not universal.

130 e of MLL-rearranged acute leukemia in infant monozygotic twins is thought to be 100% with a very shor

131 a S), parent-offspring pairs (lambda O), and monozygotic twins (lambda M) and in terms of the recombi

132 ry PDL cell cultures from patients with HPP (monozygotic twin males) were established to assay ALP ac

133 The sample included 30 monozygotic twins matched to 72 control participants and

134 similarity of close relatives (particularly monozygotic twins), maternal relatives, relatives-in-law

135 at CNV analysis in phenotypically discordant monozygotic twins may provide a powerful tool for identi

136 autobiographical interviews with 14 pairs of monozygotic twins (mean age 51.2) rigorously discordant

137 in vivo neuroanatomic imaging on 14 pairs of monozygotic twins (mean age 9.7, s.d. 1.9 years), we fou

138 fferences in neuroanatomy between discordant monozygotic twins might be associated with the narrow an

139 only 33% of responding centers would allow a monozygotic twin minor to donate a kidney to his or her

140 dy (EWAS) was performed on buccal cells from monozygotic-twins (MZ) reared together as children, but

141 Monozygotic twins (n = 1), dizygotic twins (n = 3) and t

142 ple of 684 subjects took part, consisting of monozygotic twins (n = 410, with 51 patients from concor

143 n the Social Reciprocity Scale were 0.73 for monozygotic twins (N=98 pairs) and 0.37 for dizygotic tw

144 sibling pair sample (full siblings: n = 513; monozygotic twins: n = 207; dizygotic twins: n = 189), t

145 c aetiology; appropriate clinical action for monozygotic twins needs consideration.

146 the question of how and when concordance in monozygotic twins occur, we have obtained fibroblasts fr

147 The cumulative risk by age 40 years in monozygotic twins of men with testicular cancer was 14%

148 The very high incidence in monozygotic twins of patients indicates that a high prop

149 The incidence in a prospective study of monozygotic twins of patients was approximately constant

150 isk of breast cancer was 34.7 (9.5-126.5) in monozygotic twins of women in whom breast cancer had occ

151 ders have higher than expected prevalence of monozygotic twinning, of assisted reproductive technolog

152 Analysis of mRNA in two haemophilic monozygotic twins offers novel information on the organi

153 aneous occurrence of the long QT syndrome in monozygotic twin offspring of unaffected parents.

154 s: This case series included 2 pairs of male monozygotic twins; one pair was aged 51 years and the ot

155 between psoriasis and obesity was diluted in monozygotic twins (OR, 1.43; 95% CI, 0.50-4.07; P = .50)

156 AUTS2) that spans the 7q11.2 breakpoint in a monozygotic twin pair concordant for autism and a t(7;20

157 ferences were detected within, than between, monozygotic twin pair genomes.

158 rt the genome sequences of one MS-discordant monozygotic twin pair, and messenger RNA transcriptome a

159 tic features, but cases include a discordant monozygotic twin pair, individuals with idiopathic devel

160 t the first case of discordance in an infant monozygotic twin pair.

161 tion450 BeadChip data were available for 769 monozygotic twin pairs (mean age = 36 years, range = 18-

162 5% CI, 1.38-1.98) and with 3 outcomes within monozygotic twin pairs (mean within-pairs OR, 1.77; 95%

163 onfidence interval [95% CI] 0.65-0.80) among monozygotic twin pairs and 0.47 (95% CI 0.39-0.55) in di

164 s contain notes with incorrect pitch, to 136 monozygotic twin pairs and 148 dizygotic twin pairs.

165 eDIP-seq) in whole-blood-derived DNA from 27 monozygotic twin pairs and follow up results with replic

166 om 124 unrelated individuals, as well as six monozygotic twin pairs and their mothers, and generate c

167 n, but not over the 10 yr from 12 to 22; and monozygotic twin pairs are statistically not more simila

168 d dizygotic twin pairs and 3 outcomes within monozygotic twin pairs at 10 years.

169 The subjects were 16 monozygotic twin pairs between the ages of 5 and 14 year

170 eneity, we made use of a unique cohort of 43 monozygotic twin pairs clinically discordant for MS and

171 twin pairs discordant for schizophrenia, 13 monozygotic twin pairs concordant for schizophrenia, and

172 negativity, P300, and P50 suppression in 16 monozygotic twin pairs concordant for schizophrenia, nin

173 enome-wide analysis of DNA methylation of 18 monozygotic twin pairs discordant for alcohol use disord

174 control analyses among 643 dizygotic and 365 monozygotic twin pairs discordant for asthma to ascertai

175 Half-siblings, full-siblings, and monozygotic twin pairs discordant for AUD were obtained

176 Nineteen white, male, monozygotic twin pairs discordant for CVD deaths were in

177 k (and a prosaccade control condition) by 10 monozygotic twin pairs discordant for DSM-IV schizophren

178 pbringing could be excluded by validation in monozygotic twin pairs discordant for MS.

179 We replicated our results in 31 monozygotic twin pairs discordant for renal function.

180 Two additional monozygotic twin pairs discordant for schizophrenia also

181 e obtained by established procedures from 26 monozygotic twin pairs discordant for schizophrenia, 13

182 win pairs concordant for schizophrenia, nine monozygotic twin pairs discordant for schizophrenia, and

183 association study across 406,365 CpGs in 52 monozygotic twin pairs discordant for T1D in three immun

184 DNA methylation data in adipose tissue from monozygotic twin pairs discordant for T2D and independen

185 Differences in methylation between monozygotic twin pairs discordant for T2D were subsequen

186 her validated our findings from FH(+) men in monozygotic twin pairs discordant for T2D, and 40% of 65

187 ation of miRNAs using adipose tissue from 14 monozygotic twin pairs discordant for T2D.

188 so identified copy number variants (CNVs) in monozygotic twin pairs discordant for T2D.

189 allelic expression is highly similar within monozygotic twin pairs for many loci, implying that alle

190 s with adult height in 140 height-discordant monozygotic twin pairs from the California Twin Program.

191 available for 1987 adult and 648 adolescent monozygotic twin pairs from the Netherlands Twin Registe

192 Two monozygotic twin pairs had X-inactivation ratios skewed

193 sess mismatch in placental function in seven monozygotic twin pairs naturally matched for genetic gro

194 Within monozygotic twin pairs only, associations between infant

195 microbiome and virome diversity in 21 adult monozygotic twin pairs selected for high or low microbio

196 thylation at birth in 41 leukemia-discordant monozygotic twin pairs using the Illumina EPIC array on

197 stically significant, and the correlation in monozygotic twin pairs was significantly greater than th

198 Twenty body mass index (BMI)-discordant monozygotic twin pairs were supplemented with an escalat

199 ed association using pairwise analysis among monozygotic twin pairs who are discordant in their physi

200 dentified 175 male-male and 69 female-female monozygotic twin pairs who differed by at least 2 years

201 us adipose tissue (SAT) samples from healthy monozygotic twin pairs, 22.8-36.2 years of age, who were

202 The participants were 345 monozygotic twin pairs, 337 dizygotic twin pairs, 306 bi

203 igh correlations in visual area size between monozygotic twin pairs, and lower but still substantial

204 on were associated with height difference in monozygotic twin pairs, independent of genome, birth len

205 For studies within monozygotic twin pairs, the combined estimate was -0.6 m

206 CD4(+) lymphocytes from three MS-discordant, monozygotic twin pairs.

207 ytes (PBL) and buccal cells from a series of monozygotic twin pairs.

208 the retina, and they are correlated between monozygotic twin pairs.

209 is in the heavy-smoking member of discordant monozygotic twin pairs.

210 ion patterns of CSF cells from MS-discordant monozygotic twin pairs.

211 tween global DNA methylation and IR using 84 monozygotic twin pairs.

212 ance imaging experiments in two adult female monozygotic twins (patient 1 and patient 2) with equival

213 We describe a remarkable case of monozygotic twins presenting with CALR mutation-positive

214 ak frequencies were highly correlated across monozygotic twins (r = 0.88), but not across dizygotic t

215 el of liver fibrosis also correlated between monozygotic twins (r(2) = 0.48; P < .002) but not betwee

216 ence of hepatic steatosis correlated between monozygotic twins (r(2) = 0.70; P < .0001) but not betwe

217 On all ASD measures, correlations among monozygotic twins (range, 0.77-0.99) were significantly

218 Among monozygotic twins reared apart and discordant for H. pyl

219 ly related to increased risk of asthma among monozygotic twins (relative risk for 2,000 g vs. 2,500 g

220 ected current diagnoses of eating disorders, monozygotic twins resembled one another much more in ter

221 In support of this hypothesis, studies in monozygotic twins revealed increasing epigenetic differe

222 Additional analyses with monozygotic twins revealed significant correlations with

223 ordant for schizophrenia, and several normal monozygotic twin samples.

224 In 5 of 8 monozygotic twin sets, both individuals had PBC (pairwis

225 ofound DNAm plasticity during embryogenesis, monozygotic twins show indistinguishable childhood methy

226 mmune responses and viral evolution in adult monozygotic twins simultaneously infected with the same

227 Monozygotic twin sisters, with nonhematologic symptoms o

228 Human monozygotic twin studies, animal studies, and genetic mo

229 Here, we combine the power of a within-monozygotic twin study design with longitudinal neuroima

230 ders as well as the low concordance rates in monozygotic twins suggest that a combination of other fa

231 iological studies and a discordance of MS in monozygotic twins suggest that the disorder is acquired.

232 ncluding discordant diabetes incidence among monozygotic twins suggested a role for epigenetics in di

233 ning handedness of the progeny of discordant monozygotic twins suggests that lefties are one gene apa

234 risks of these cancers in dizygotic than in monozygotic twins support a prenatal aetiology, and are

235 zygotic twins is similar to that in pairs of monozygotic twins, supporting a role of non-genetic risk

236 Resemblance was greater in the monozygotic twins than in the dizygotic twins or in the

237 alyze genetic differences between 2 pairs of monozygotic twins that had discordant aortic valve morph

238 show, via the shared prenatal circulation of monozygotic twins, that weak selection conferred by stem

239 os (95% CI) ranging from 1.46 (1.07-1.98) in monozygotic twins to 1.10 (1.09-1.11) in cousins.

240 Twin studies show the concordance in monozygotic twins to be between 65-70%, compared to betw

241 This is the largest genetic study of monozygotic twins to date by an order of magnitude, evid

242 for AUD onset given divorce among discordant monozygotic twins to equal 3.45 and 3.62 in men and wome

243 ic mechanisms, we generated human iPSCs from monozygotic twins to investigate how genetic background,

244 the similarity of sexual orientation in the monozygotic twins to the similarity in the same-sex dizy

245 in control analyses among disease-discordant monozygotic twins, tuberculosis risk was 46% lower for e

246 tism and 84 singleton controls, we find high monozygotic twin-twin concordance (0.91) and relatively

247 ases complex structural variant in a pair of monozygotic twins using Oxford Nanopore Technologies (ON

248 Measures: Genetic coding variations between monozygotic twins using whole-exome sequencing and targe

249 imate of discordance of an episode of AOM in monozygotic twins was 0.04 compared with 0.49 in dizygot

250 One set of monozygotic twins was detected among the 304 meioses map

251 The proband-wise concordance rate for monozygotic twins was double that of dizygotic twins (0.

252 rate per 100,000 person-years for ASD among monozygotic twins was estimated to be 153.0 (95% CI, 56.

253 ratio for drug abuse in pregnancy-discordant monozygotic twins was even stronger, at 0.17 (95% CI=0.1

254 By studying monozygotic twins, we demonstrated that there is evidenc

255 D4(+) T and CD8(+) T-lymphocyte subsets from monozygotic twins, we quantify the impact of heritable f

256 In conclusion, by analysing data from monozygotic twins, we robustly demonstrate that DNA meth

257 Using high-throughput sequence analysis of monozygotic twins, we show that variation in naive V(H)

258 Only two of seven pairs of monozygotic twins were concordant for ectopic canines.

259 Monozygotic twins were considered if there were similari

260 The neural activity patterns in monozygotic twins were significantly more similar than i

261 volumes for HME and non-HME cases, including monozygotic twins where one sibling had HME.

262 e have analyzed convergence in seven sets of monozygotic twins which suggests that genetic factors ma

263 We report a rare case of a monozygotic twin who presented with primary rhabdomyosar

264 The monozygotic twin who used cannabis frequently was more l

265 at differences in smoking level exposure for monozygotic twins who are both current smokers but diffe

266 Investigating neuroanatomic differences in monozygotic twins who are discordant for autism can help

267 We present a case of monozygotic twins who are discordant for breast cancer a

268 d in peripheral blood mononuclear cells from monozygotic twins who are discordant for MS.

269 ns and growth, we interviewed the mothers of monozygotic twins who differed in self-reported adult he

270 stigate several brain regions of interest in monozygotic twins who varied in degree of phenotypic dis

271 This co-twin study investigated monozygotic twins who were discordant for schizophrenia

272 on in IRF6 in the affected twin of a pair of monozygotic twins who were discordant for VWS.

273 ldhood on the acquisition of H. pylori among monozygotic twins who were reared apart and had an ident

274 Offspring of an alcohol-abusing monozygotic twin whose co-twin was AD were also more lik

275 cted (ie, no history of abuse or dependence) monozygotic twin whose co-twin was AD were no more likel

276 Studying monozygotic twins with ALL provides a unique means of un

277 e identified and compared CNAs in 5 pairs of monozygotic twins with concordant ETV6-RUNX1-positive AL

278 Studies on monozygotic twins with concordant leukemia and retrospec

279 Whole genome sequencing analysis of the six monozygotic twins with discordant HCM phenotypes did not

280 We studied 19 pairs of monozygotic twins with either concordant or discordant p

281 We found that monozygotic twins with focal bilateral amygdala lesions

282 Vascular programming is evident in monozygotic twins with intertwin transfusion and is alte

283 The families included 3 pairs of monozygotic twins with juvenile dermatomyositis, 11 fami

284 g 58 singletons, 132 dizygotic twins, and 98 monozygotic twins with rsfMRI scans during the first 2 y

285 wever, the striking concordance of a pair of monozygotic twins with Waardenburg syndrome (WS) and pre

286 of breast cancer in dizygotic compared with monozygotic twins younger than 30 years (odds ratio 2.3