ライフサイエンスコーパス: morbid

1 Associations persisted when pre-morbid ability was adjusted for, but as expected were no

2 cerebral organoids could be explored as pre-morbid AD-risk population detector and a system for hypo

3 ) or severe LATE-NC (mostly stage 3) with co-morbid ADNC (n = 30).

4 PC1) gene is associated with early-onset and morbid adult obesity.

5 be associated with extreme (early-onset and morbid-adult) obesity and type 2 diabetes independent of

6 BS and other functional GI disorders with co-morbid affective disorders and temporal association of s

7 or frailty (Clinical Frailty Score) were non-morbid, age- and gender-matched to survivors.

8 onal self-regulation (DESR) is prevalent and morbid among patients with attention deficit hyperactivi

9 Cirrhosis is morbid and increasingly prevalent, yet the U.S. health c

10 Schwannomas are common, highly morbid and medically untreatable tumors that can arise i

11 We used the same subjects for morbid and moderate obesity association studies.

12 n-small cell lung cancer (NSCLC) is a highly morbid and mortal cancer type that is difficult to eradi

13 Nevertheless, public knowledge of PAD as a morbid and mortal disease has not been previously assess

14 ate with this progress has been a decline in morbid and mortal events.

15 increases, so does the occurrence of highly morbid and mortal outcomes, including heart failure and

16 Head and neck cancer remains a morbid and often fatal disease and at the present time f

17 Although GSW is a more morbid and often fatal injury, the general principles of

18 n decades after its discovery, CN1 remains a morbid and potentially fatal disorder.

19 Stroke is a morbid and potentially mortal complication among patient

20 osis of the jaw (MRONJ) is an infrequent but morbid and potentially serious condition associated with

21 Group B Streptococcus causes a variety of morbid and sometimes fatal conditions affecting individu

22 isional hernia (IH) remains a common, highly morbid, and costly complication.

23 Delirium is a common, morbid, and costly postoperative complication.

24 neous coronary intervention (PCI) is common, morbid, and costly; increases patients' mortality risk;

25 squamous cell carcinoma (HNSCC) is a common, morbid, and frequently lethal malignancy.

26 l aortic aneurysm (AAA) disease is a common, morbid, and highly lethal pathology.

27 Obliterative bronchiolitis is a frequent, morbid, and usually refractory complication of lung tran

28 The surgery is complex and often highly morbid, and where possible patients should be given peri

29 pression Scale (HADS) was used to measure co-morbid anxiety and depression.

30 ould be a common epigenetic mechanism for co-morbid anxiety and psychostimulant addiction.

31 n therapy has shifted to more targeted, less morbid approaches.

32 Atrial fibrillation (AF) is a common and morbid arrhythmia.

33 5% were overweight and 47% were obese by pre-morbid BMI measured 4.3 +/- 3.1 years before HF diagnosi

34 loss at diagnosis (p<0.0001), but not to pre-morbid BMI or BMI at diagnosis.

35 measured >/=6 months before incident HF (pre-morbid BMI) to evaluate the association of overweight (B

36 ociated osteonecrosis of the jaw (BONJ) is a morbid bone disease linked to long-term bisphosphonate u

37 lume (TICV) as a quantitative measure of pre-morbid brain size and a vicarious indicator of reserve.

38 d radial artery occlusion are typically less morbid but occur much more frequently.

39 xpands on the genetic basis of this rare and morbid cardiomyopathy.

40 Despite the rise in co-morbid cardiovascular disease risk factors like hyperlip

41 -traumatic stress disorder (PTSD) exhibit co-morbid chronic pain and amygdala dysregulation.

42 While data suggest a number of costly and morbid chronic sequelae associated with these infections

43 A vocabulary-based test estimated pre-morbid cognitive ability.

44 y in other genetic mutant mouse models of co-morbid cognitive and autistic-like disabilities.

45 predictive capacity for the most common and morbid complication after PD - clinically relevant pancr

46 reatic fistula (CR-POPF)-the most common and morbid complication after PD.

47 OPF occurrence, which is the most common and morbid complication following pancreatoduodenectomy.

48 MaSBO is a morbid complication of advanced cancers for which the op

49 GVHD remains a lethal and morbid complication of allogeneic bone marrow transplant

50 oint inhibitor pneumonitis (CIP) is a highly morbid complication of immune checkpoint immunotherapy (

51 Pulmonary hypertension (PH) is a common and morbid complication of left heart disease with 2 subtype

52 VTE is an underappreciated and potentially morbid complication of SCD.

53 Pneumonia is a morbid complication of stroke, but evidence-based strate

54 The most frequent morbid complication was wound infection, more commonly o

55 ys and targets for prevention of this common morbid complication.

56 ive referral could reduce occurrence of this morbid complication.

57 nction of the gut, and the avoidance of such morbid complications as abdominal compartment syndrome a

58 ection are at risk for developing costly and morbid complications, although the actual prevalence of

59 nately, these treatments are associated with morbid complications.

60 y can be life-saving, but is associated with morbid complications.

61 It remains to be determined if the co-morbid concurrence of large infarct and beta-amyloid (Ab

62 ipheral neuropathy is a highly prevalent and morbid condition affecting 2% to 7% of the population.

63 compensated heart failure (ADHF) is a highly morbid condition among adults.

64 Falling is a common and morbid condition among elderly persons.

65 Cardiogenic shock is a highly morbid condition in which inadequate end-organ perfusion

66 Pulmonary vein (PV) stenosis is a highly morbid condition that can result after catheter ablation

67 ey transplantation (NODM) is an important co morbid condition that is associated with inferior graft

68 ed acute kidney injury (AKI) is a common and morbid condition that is distinguishable from typical is

69 hemic rest pain and tissue loss, is a highly morbid condition that leads to the loss of ambulation an

70 osttransplant malignancy is an expensive and morbid condition that warrants attention in efforts to i

71 Acute PEH represents a highly morbid condition, and treatment in high-volume centers p

72 ation has decreased, but it remains a highly morbid condition.

73 ence for the management of infants with this morbid condition.

74 imal management of patients with this highly morbid condition.

75 imated prevalences and prevalence ratios for morbid conditions affecting the women during a 1-year po

76 The extent of surgery and co-morbid conditions also have a major impact.

77 reus (MRSA) continues to be a major cause of morbid conditions and death.

78 ker of renal failure and, possibly, of other morbid conditions in full-term and very low birth weight

79 regression coefficients for the impact of 98 morbid conditions on PF.

80 may have a role in the detection of nonrenal morbid conditions such as sepsis.

81 IMIDs may impact these co-morbid conditions through shared genetic risks, common e

82 Symptoms and co-morbid conditions were similar among those whose IgA tTG

83 ologic causes of anxiety, underrecognized co-morbid conditions, and medical illnesses that masquerade

84 Periodontitis and type 2 diabetes are co-morbid conditions, both characterized by infectious susc

85 de is accompanied by an increased risk of co-morbid conditions, including the intersection of diabete

86 are attempted on patients with increasing co-morbid conditions, it will be important to both utilize

87 rations in cardiac performance related to co-morbid conditions, preoperative myocardial insults and i

88 maintenance of these disorders (ie, sex, co-morbid conditions, types of trauma exposure, and behavio

89 cause premature death indirectly through co-morbid conditions.

90 by utilising GWA studies on ADHD and its co-morbid conditions.

91 and their caregivers about the very real and morbid consequences of being this sick is essential.

92 occurrence, however, can be associated with morbid consequences, including requirement for surgical

93 tibility or reserve (age, low education, pre-morbid dependency, leucoaraiosis), baseline cognition, a

94 asia, baseline cognition, low education, pre-morbid dependency, leucoaraiosis, and diabetes (p<0.0001

95 ough the causes remain poorly understood, co-morbid depression and the first 6 months after epilepsy

96 positive for PTSD (7.9%, N = 42), all had co-morbid depression and/or anxiety.

97 of anxiety (N = 15), depression (N = 69), co-morbid depression/anxiety (N = 153), substance use disor

98 erve as a useful genetic animal model for co-morbid depressive disorder and parkinsonism.

99 ulness of this platform in costly and highly morbid diabetic wounds by identifying a subpopulation of

100 of hopefully avoiding progression to highly morbid, difficult to treat, and quite often irreversible

101 of physiological reserve and severity of co-morbid disease are required to improve risk stratificati

102 nfected necrotizing pancreatitis is a highly morbid disease with poor outcomes.

103 argeted fashion offer promise in this highly morbid disease.

104 ry to develop preventive strategies for this morbid disease.

105 nal and extraintestinal), family history, co-morbid diseases and conditions associated with celiac di

106 They might also have co-morbid disorders including intellectual impairment, seiz

107 amily focused grief therapy is to reduce the morbid effects of grief among families at risk of poor p

108 ard ratio 1.51, 95% CI 1.2 to 1.9) and first morbid event (hazard ratio 1.53, 95% CI 1.28 to 1.84) wa

109 interval, 1.014 to 1.019; P<0.001) and first morbid event (hazard ratio, 1.020; 95% confidence interv

110 o 2.26; P=0.94), as was the hazard for first morbid event (HR 1.26, 95% CI 1.01 to 1.57 versus HR 1.4

111 nterval [CI] 1.01 to 1.62, P=0.05) and first morbid event (HR 1.28, 95% CI 1.06 to 1.55, P=0.01).

112 with the risks of future mortality and first morbid event also after adjustment for clinical prognost

113 ithout CKD and reduced the risk of the first morbid event in patients with CKD, which suggests its be

114 The cumulative likelihood of death and first morbid event increased with increasing quartile of CRP.

115 ghtened risk of acute limb ischemia (ALI), a morbid event that may result in limb loss.

116 The 2 primary outcomes were death and first morbid event, defined as death, sudden death with resusc

117 ntly (P<0.0001) associated with the risks of morbid event, mortality, and hospitalization for heart f

118 erval, 1.001 to 1.014; P=0.02) but not first morbid event.

119 usted increased risk for every postoperative morbid event: mortality (odds ratio [OR], 1.77; 95% conf

120 ose exposure, prolonged hospitalization, and morbid events after complex congenital heart surgery.

121 ociated with increased risk of postoperative morbid events after isolated coronary artery bypass graf

122 cardiovascular abnormalities eventuating in morbid events are detectable in the arteries and heart b

123 Mortality and morbid events are insensitive guides to the efficacy and

124 Efforts to prevent atherosclerotic morbid events have focused primarily on risk factor prev

125 The beneficial effect of valsartan on first morbid events was similar in those with and without CKD

126 nd perioperative variables and postoperative morbid events were prospectively collected concurrently

127 slow progression and delay or prevent future morbid events.

128 the general population and unaffected by co-morbid factors.

129 at the heterogeneity of both the core and co-morbid features predicts a heterogeneous pattern of neur

130 s-related lung injury is the most common and morbid form of acute lung injury.

131 's disease patients, only two had primary co-morbid FTD-spectrum pathology (progressive supranuclear

132 hort further identified mutations in a novel morbid gene TXNDC15, encoding a thiol isomerase, based o

133 indings strongly suggest that CCDC88B is the morbid gene underlying the pleiotropic effect of the 11q

134 ng complementary information to characterize morbid genes at infectious and inflammatory disease loci

135 Finally, we show that the morbid genome of ciliopathies encompasses many founder m

136 Our study increases our understanding of the morbid genome of ciliopathies.

137 Our results expand the morbid genome of ID and support the adoption of genomics

138 conditions; however, our knowledge of their morbid genome, pleiotropy, and variable expressivity rem

139 rovide a foundational map of large SV in the morbid human genome and demonstrate a previously underap

140 GS pipeline dealing with the analysis of the morbid human genome.

141 therefore warrant a careful assessment of co-morbid illness seemingly unrelated to the bleed.

142 ets that could lead to therapeutics for this morbid immune related adverse event.

143 ReLT-KT is a highly morbid increasingly performed procedure.

144 n behavioral abnormalities could reflect pre-morbid individual differences in the cognitive domain of

145 imulation (TMS) to explore the impact of pre-morbid individual differences on post-lesion performance

146 approach to understanding the impact of pre-morbid individual variation on post-lesion outcomes that

147 Staphylococcus aureus (MSSA) bacteremia is a morbid infection.

148 a critical pathophysiologic event in highly morbid inflammatory conditions such as sepsis and acute

149 survival of intestinal crypt clonogens after morbid irradiation.

150 rus; to clarify the relationship between pre-morbid language organization and susceptibility to unila

151 , OMIM had over 24,600 entries, and the OMIM Morbid Map Scorecard had 6,259 molecularized phenotypes

152 e table of genes and genetic phenotypes, the Morbid Map.

153 otypic presentation of mood disorders and co-morbid medical conditions in this family.

154 In the current study, a co-morbid model of AKI was developed to better mimic the pa

155 f sequelae, such as coagulopathy, infection, morbid myocardial events, and death after surgery.

156 patients typically present with multiple co-morbid neuropathologies at autopsy, but the impact of th

157 ldhood obesity (P = 0.0003) and common adult morbid obesity (0.0003 < P < 0.007).

158 of overweight (39.8%), obesity (26.6%), and morbid obesity (3.6%) were similar in most geographic lo

159 rdized difference, 0.17); had lower rates of morbid obesity (4.8% vs 7.6%; standardized difference, 0

160 nfidence interval (CI): 1.14, 3.20), whereas morbid obesity (BMI >/= 40) was suggestive of increased

161 cant predictors of a wound complication were morbid obesity (BMI >30), having had a MT, low preoperat

162 Morbid obesity (body mass index > or =40 kg/m(2)) is an

163 We examined the prevalence of morbid obesity (body mass index [BMI] >/= 40 kg/m(2)) am

164 nts who do not meet body weight criteria for morbid obesity (body mass index [BMI], <35 kg/m), but la

165 gn pathology (n = 48) and gastric bypass for morbid obesity (n = 40) were assessed.

166 egion in 3q29; we designated this region the morbid obesity 1 (MO1) locus.

167 Morbid obesity added 48 minutes to OT (P = 0.018), 1.1 u

168 Morbid obesity alters drug dose requirement and time cou

169 the prevalence and clinical implications of morbid obesity among patients undergoing PCI.

170 the prevalence and clinical implications of morbid obesity among patients undergoing percutaneous co

171 iary protein CEP19 in humans and mice causes morbid obesity and defines a target for investigating th

172 of leukocyte activation and inflammation in morbid obesity and diabetes and diminish with weight los

173 holds promise as a therapeutic strategy for morbid obesity and diabetes.

174 ion of inflammation resolution prevents from morbid obesity and hyperglycemia under dietary overload

175 Leptin-deficient mice (ob/ob) exhibit morbid obesity and insulin resistance.

176 considered the most effective treatment for morbid obesity and its comorbidities; however, a systema

177 device may be suitable for the treatment of morbid obesity and its related comorbidities.

178 f the most efficient procedures for treating morbid obesity and results in weight-loss and improvemen

179 is a reasonable choice for the treatment of morbid obesity and should be covered by both public and

180 (LAMB3) gene showing strong association with morbid obesity and thereby risk of type 2 diabetes.

181 rt were patients with a primary diagnosis of morbid obesity and who underwent laparoscopic Roux-en-Y

182 epresent what we believe is a novel model of morbid obesity associated with an improved metabolic pro

183 Paradoxically, even morbid obesity associates with better outcomes in studie

184 ry laparoscopic gastric bypass operation for morbid obesity between May 1, 2007, and September 30, 20

185 obese controls and accounted for 0.7% of our morbid obesity cases (body mass index (BMI) >or= 40 kg m

186 Morbid Obesity Centre, Vestfold Hospital Trust.

187 ass is the procedure of choice when GERD and morbid obesity coexist.

188 age points) also was observed in adults with morbid obesity compared with normal-weight controls.

189 The number of patients with obesity and morbid obesity continues to increase.

190 ic gastric banding as a primary treatment of morbid obesity has been widely accepted, the effects of

191 Morbid obesity has no clinically significant impact on t

192 The prevalence of morbid obesity has risen sharply in recent years, even a

193 Roux-en-Y gastric bypass (RYGB) surgery for morbid obesity in a large nationwide cohort.

194 The prevalence of obesity, and morbid obesity in particular, continues to rise rapidly

195 ght to evaluate the prognostic impact of pre-morbid obesity in patients with HF.

196 ency coding variant that was associated with morbid obesity in the LAMB3 gene.

197 shift in the type of procedure performed for morbid obesity in the United States toward sleeve gastre

198 Morbid obesity is a barrier to kidney transplantation du

199 Morbid obesity is a global health epidemic.

200 Morbid obesity is an epidemic in the United States and p

201 Morbid obesity is associated with higher mortality on th

202 Morbid obesity is associated with unacceptable high recu

203 Morbid obesity is increasing in prevalence among patient

204 The number of bariatric interventions for morbid obesity is increasing worldwide.

205 Morbid obesity is increasingly becoming a major public h

206 frequently used and effective treatment for morbid obesity is Roux-en-Y gastric bypass surgery (RYGB

207 Morbid obesity may be accompanied by diabetes and painfu

208 and differing socio-cultural perceptions of morbid obesity on racial disparities.

209 Morbid obesity predicted higher post-LT mortality before

210 pproximately 1% of eligible individuals with morbid obesity receive bariatric surgery.

211 As the number of people with morbid obesity rises, so will the number of bariatric pr

212 Roux-en-Y gastric bypass, in the Adolescent Morbid Obesity Surgery (AMOS) study.

213 adhere to practice guidelines that consider morbid obesity to be a contraindication to liver transpl

214 A NASH Clinical Scoring System for Morbid Obesity was derived to predict the probability of

215 sence of 5 conditions commonly comorbid with morbid obesity were examined for morbidly obese patients

216 Patients with morbid obesity were included at two obesity centers in S

217 The relationship of morbid obesity with LT outcomes and survival benefit in

218 In addition, morbid obesity's impact on many organ systems decreases

219 esity (odds ratio, 2.4 [95% CI: 1.1, 5.4] or morbid obesity).

220 For type 2 diabetes, moderate and morbid obesity, and for both the Q121 and three-marker h

221 Baseline depressive symptoms, morbid obesity, and intensive care unit benzodiazepine d

222 nsity and angiogenic capacity decreased with morbid obesity, and subcutaneous, but not visceral, adip

223 term (<2 years) efficacy of RYGB surgery for morbid obesity, corroborated by meta-analytic techniques

224 18-month-old female child who presented with morbid obesity, decreased linear growth, and reversal of

225 Leptin deficiency in mice and humans causes morbid obesity, diabetes, and various neuroendocrine ano

226 past year have focused on three broad areas: morbid obesity, gastric cancer, and peptic ulcer disease

227 though some individual offspring suffer from morbid obesity, others escape the malprogramming.

228 P = 0.46 for type 2 diabetes, moderate, and morbid obesity, respectively).

229 elucidating the key networks associated with morbid obesity, response to RYGB, and disease as a whole

230 Among patients with morbid obesity, the use of vagal nerve block therapy com

231 Morbid obesity-adjusted rates of surgery were then calcu

232 t mechanisms of cardiovascular protection in morbid obesity.

233 ]) for the classification of liver injury in morbid obesity.

234 tical eligibility criteria for patients with morbid obesity.

235 n increasingly popular form of treatment for morbid obesity.

236 ing postoperative outcomes in primary SG for morbid obesity.

237 astric bypass surgery-induced weight loss in morbid obesity.

238 routine coverage for SG for the treatment of morbid obesity.

239 c fat using 3T magnetic resonance imaging in morbid obesity.

240 nd db/db mice in the absence of diabetes and morbid obesity.

241 receptor-deficient (db/db) mice that develop morbid obesity.

242 ral tissue, but this capacity decreases with morbid obesity.

243 festyle changes alone in treating adolescent morbid obesity.

244 based on the complicating issues surrounding morbid obesity.

245 tes in patients who do not meet criteria for morbid obesity.

246 in 48 of 1282 patients (3.7%) after RYGB for morbid obesity.

247 , and may have implications for treatment of morbid obesity.

248 patients with gastric motility disorders or morbid obesity.

249 in the ob gene causes leptin deficiency and morbid obesity.

250 f death increased 7.4 times in patients with morbid obesity.

251 in 48 of 904 patients (5.3%) after RYGBP for morbid obesity.

252 syndrome (IBS) is prevalent in patients with morbid obesity.

253 hepatic fibrosis in patients with severe to morbid obesity.

254 Here, we describe an autosomal-recessive morbid-obesity syndrome and identify the disease-causing

255 water balance are among the most common and morbid of the electrolyte disturbances, and are reflecte

256 with a disproportionately higher increase in morbid or class III obesity, and obesity adversely affec

257 nalysis of social exposure to others who are morbid or deceased shows considerable variation in how t

258 cision-making to prevent the occurrence of a morbid or mortal ischemic event.

259 CMV infection may contribute to risk for morbid outcomes in treated HIV infection.

260 raditional risk factors for many of the most morbid outcomes of CKD.

261 on and are associated with increased risk of morbid outcomes.

262 ychiatric patients, a high risk group for co-morbid pain disorders and increased perception of pain.

263 bers of surgeries involving high risk, multi-morbid patients, coupled with inconsistencies in the pra

264 ing that Cpc-PH may be a distinct and highly morbid PH subphenotype.

265 terventions to change the trajectory of this morbid phenotype.

266 To delineate some of the major morbid phenotypes that have emerged in pediatric obstruc

267 s schizophrenia and bipolar disorder have co-morbid physical conditions, suggesting that systemic alt

268 ffective management of mental illness and co-morbid physical health problems as well as consideration

269 y have severely limited efficacy in these co-morbid populations.

270 %) patients who had surgery underwent a less morbid procedure than planned.

271 Radical cystectomy is a morbid procedure with rather long hospital stay and comp

272 order and cocaine use disorder are highly co-morbid psychiatric conditions.

273 sm and to ameliorate its risk and that of co-morbid psychiatric conditions.

274 , the impact of DAAs on the management of co-morbid psychiatric illness and neuropsychiatric sequalae

275 nicotine dependencies (CD, ND), and their co-morbid psychopathologies.

276 arthritis is an underdiagnosed, potentially morbid reactive arthritis associated with C difficile in

277 gnificant three-way interaction between "pre-morbid" reading status, stimulation, and word type, such

278 Idiopathic pulmonary fibrosis (IPF) is a morbid, refractory lung disorder with an unknown pathoge

279 ess syndrome (ARDS) is a common, lethal, and morbid respiratory complication primarily seen in the se

280 t (P = .02) when studies that did not report morbid risk estimates were excluded (in this case, OR =

281 ars that elderly patients with additional co-morbid risk factors may benefit most from off-pump coron

282 ate the effects of double predispositions on morbid risk in the offspring, which is of interest for m

283 e of 10.8 +/- 2.6 years.Main Outcome Measure Morbid risk.

284 on-specific neurodevelopmental delay with co-morbid seizure disorder accounting for 33.3%, 14.8%, 18.

285 ventive efforts to reduce the chance of this morbid side effect.

286 The BDMM identified further directly co-morbid somatic disorders, e.g. irritable bowel syndrome,

287 as a museum, showcasing dried and varnished morbid specimens--human relics of the Civil War, the ins

288 ment of anxiety disorders, depression and co-morbid substance abuse.

289 th tumour responses and reduced the need for morbid surgery in patients with GCTB.

290 can help prevent unnecessary and potentially morbid surgical and ablation procedures in a substantial

291 to improvement in quality of life after this morbid surgical procedure.

292 When indicated, the selection of a less morbid surgical technique has the potential to improve o

293 undernourished, females and in those with co-morbid systemic illnesses.

294 Myomectomy is not necessarily less morbid than hysterectomy and may have a greater failure

295 ence of the degenerative process or of a pre-morbid trait.

296 n with HIPEC is an effective but potentially morbid treatment option for peritoneal surface malignanc

297 Drug dependence (DD) is commonly co-morbid with alcohol dependence (AD).

298 LATE-NC may be co-morbid with Alzheimer's disease neuropathological change

299 Alcoholism is frequently co-morbid with post-traumatic stress disorder, but it is un

300 Severe sepsis is common and highly morbid, yet the epidemiology of severe sepsis at the fro