ライフサイエンスコーパス: morbidly

1 DS can be performed relatively safely in the morbidly and super morbidly obese, and does not require

2 efficacy for depressive symptoms that are co-morbidly associated with inflammatory disorders.

3 Pre-morbidly, however, the patients with aphasia had enjoyed

4 Morbidly ill C3H mice at 14 days had severe pulmonary ed

5 pulmonary transplantation can be applied to morbidly ill patients with excellent operative and inter

6 They were more likely to be morbidly obese (32% versus 9%), have dyslipidemia (25% v

7 ersons, 1.79 (95% CI: 1.37, 2.33) for active morbidly obese (BMI > or =35) persons, and 3.45 (95% CI:

8 studied 83 nonobese [BMI (kg/m2) <30] and 80 morbidly obese (BMI >30) middle-aged individuals (40% ma

9 , categorized as severely obese (BMI 35-40), morbidly obese (BMI 40-60), and reference (BMI 18.5-35).

10 ), 113 overweight (BMI=>27-30 kg/m2), and 55 morbidly obese (BMI>30 kg/m2) patients were compared wit

11 Values were also lower for morbidly obese (BMI, > or =40.0 kg/m(2)) participants (1

12 se (BMI, 35.1-40 kg/m(2)), and 355 (2%) were morbidly obese (BMI, 40.1-50 kg/m(2)).

13 ism indices were evaluated in 15 consecutive morbidly obese (MO) subjects before and 6 and 12 months

14 With the growing number of morbidly obese adolescents in the United States coupled

15 ities, and improvement in quality of life in morbidly obese adolescents undergoing bariatric surgery

16 following surgically induced weight loss in morbidly obese adolescents.

17 lic function before and after weight loss in morbidly obese adolescents.

18 Cardiac abnormalities are present in morbidly obese adolescents; however, it is unclear if th

19 Up to a remarkable 6% of morbidly obese adults and children studied possess singl

20 hildren with severe early-onset obesity, 568 morbidly obese adults, and 383 controls.

21 (p.T46R, p.E62K, p.H323Y, and p.D740H) in 7 morbidly obese adults.

22 In the final analysis of 1,911 morbidly obese and 1,274 control subjects, rs2076349 sho

23 28 morbidly obese and 18 lean subjects were studied with vo

24 ardiac transplantation are increased in both morbidly obese and cachectic patients compared with norm

25 ncrease in mortality was seen at 30 days for morbidly obese and cachectic recipients (12.7% and 17.7%

26 entified in a compound heterozygote that was morbidly obese and diabetic.

27 Lepr-null control males and females were morbidly obese and exhibited delayed puberty onset, no e

28 d the peripheral blood T-cell compartment of morbidly obese and lean subjects.

29 logic effects of CO2 pneumoperitoneum in the morbidly obese and make appropriate intraoperative adjus

30 erved in hunger and satiation curves between morbidly obese and nonobese groups; however, sleeve gast

31 o a functional life, and can be performed in morbidly obese and older patients.

32 In-hospital mortality was lower in morbidly obese and overweight patients and higher in und

33 y, should be applied in all patients who are morbidly obese and present for anesthetic care.

34 Sixteen million people are morbidly obese and RYGB surgery is the most effective tr

35 Obese, morbidly obese and ultra-obese patients have multiple su

36 , obese as body mass index 30-39.9 kg/m, and morbidly obese as body mass index greater than or equal

37 Morbidly obese as well as cachectic recipients demonstra

38 ue, is associated with insulin resistance in morbidly obese bariatric surgery patients.

39 e been associated with up to 6% frequency in morbidly obese children and adults.

40 Three morbidly obese children, who were congenitally deficient

41 For morbidly obese decedents (BMI >/=40 kg/m2), the predicte

42 These mice become morbidly obese due to adipocyte enlargement and tissue e

43 ith the highest rates in the underweight and morbidly obese extremes and the lowest rates in the over

44 r mortality were significantly higher in the morbidly obese group (P <.05).

45 se group and 56 (55%) patients in the non-BS morbidly obese group (P<0.0001).

46 d into normal weight, overweight, obese, and morbidly obese groups.

47 atients stratified into nonobese, obese, and morbidly obese groups.

48 Compared to the mildly obese, the morbidly obese had higher levels of SPMs-RvD3, RvD4 and

49 We treated these three morbidly obese homozygous leptin-deficient adult patient

50 Genetic studies of morbidly obese human patients and normal weight control

51 Morbidly obese human patients have been shown to possess

52 esity-associated insulin resistance and from morbidly obese humans and in in vitro models of adipocyt

53 evels of endogenous opioids are increased in morbidly obese humans and obese rats.

54 y higher in visceral than subcutaneous AT of morbidly obese humans.

55 Managing patients who are morbidly obese in the intensive care unit is associated

56 trates the successful use of lorcaserin in a morbidly obese individual with decompensated cirrhosis e

57 A morbidly obese individual's increased cardiac output req

58 1 and 2 mg/kg liposomal amphotericin B in 16 morbidly obese individuals (104-177 kg).

59 Morbidly obese individuals are predisposed to a wide ran

60 A greater number of morbidly obese individuals are undergoing bariatric surg

61 In conclusion, a significant subset of morbidly obese individuals has portal fibrosis in the ab

62 geon decisions to operate, differences among morbidly obese individuals in access to surgery, or pati

63 sms (rs1893590 [A/C] and rs1378577 [T/G]) in morbidly obese individuals indicated that elevated ABCG1

64 A significant proportion of morbidly obese individuals were predicted to have both c

65 rom fecal samples by using pyrosequencing in morbidly obese individuals, explored before (0 mo), 3 mo

66 development of esophageal adenocarcinoma in morbidly obese individuals.

67 Based on body weight, morbidly obese leptin-deficient ob/ob mice have less bon

68 Morbidly obese Medicare patients who underwent bariatric

69 ctivated K(+) (BK) channel was identified in morbidly obese men carrying a BK gene variant, supportin

70 urgery, SPM and platelet levels decreased in morbidly obese nondiabetic subjects but not in diabetic

71 d adipose tissue biopsies were obtained from morbidly obese nondiabetic subjects undergoing bariatric

72 s of this study when compared with a similar morbidly obese nonsurgical group (P < 0.001).

73 ed groups (studies that exclusively enrolled morbidly obese or diabetics or pediatric) and no data on

74 he OR rising to 4.03 (95% CI, 3.74-4.33) for morbidly obese participants (body mass index, >40 kg/m(2

75 Compared to the lean parturient, the morbidly obese parturient has an increased likelihood fo

76 neral anesthesia for cesarean section in the morbidly obese parturient is associated with increased m

77 to describe the anesthetic management of the morbidly obese parturient.

78 d to decrease potential complications in the morbidly obese parturient.

79 hysical and care needs of the critically ill morbidly obese patient but also navigate, both personall

80 proper attention to their special needs, the morbidly obese patient can safely undergo thoracic surge

81 GB) controls type 2 diabetes mellitus in the morbidly obese patient more effectively than any medical

82 e the management and improve outcomes of the morbidly obese patient presenting for any surgery.

83 and laryngoscopy for tracheal intubation the morbidly obese patient should be in the reverse Trendele

84 ive long-term improvement in diabetes in the morbidly obese patient with diabetes.METHODS We evaluate

85 e United States to induce weight loss in the morbidly obese patient, long-term follow-up continues to

86 A total of 2045 severely or morbidly obese patients (BMI >/= 35 kg/m, aged between 6

87 e studied AF type before and after BS in 220 morbidly obese patients (body mass index, >=40 kg/m(2)).

88 rillation have had minimal representation of morbidly obese patients (ie, body-mass index [BMI] >=40

89 we analyzed NUPR1 expression in a cohort of morbidly obese patients (MOPs), with simple fatty liver

90 eralis) LCACoA content and insulin action in morbidly obese patients (n = 11) before and after weight

91 Three groups were studied: morbidly obese patients (n = 16), morbidly obese patient

92 obese patients (P=0.020), and 41% higher for morbidly obese patients (P=0.015).

93 We matched 51 morbidly obese patients [body mass index >=40 kg/m(2)] w

94 ntestinal motility and hormonal responses in morbidly obese patients after sleeve gastrectomy has not

95 Effective weight loss was achieved in morbidly obese patients after undergoing bariatric surge

96 Morbidly obese patients also benefited more from LT (88%

97 splant and sleeve gastrectomy is feasible in morbidly obese patients and adds little additional opera

98 to identify factors associated with MetS in morbidly obese patients and predictors of its remission

99 utations in the melanocortin MC4 receptor in morbidly obese patients and the finding that intranasal

100 ond one from the across-tissue comparison of morbidly obese patients and the other from the across-po

101 , trauma-related procedures and many others, morbidly obese patients are most consistently cared for

102 adverse consequences of pneumoperitoneum in morbidly obese patients are similar to those observed in

103 e, we studied brain glucose metabolism in 22 morbidly obese patients before and 6 months after bariat

104 y artery disease (TCAD) was not increased in morbidly obese patients but cachectic patients had a sig

105 We conclude that morbidly obese patients dedicate a disproportionately hi

106 Extremely or morbidly obese patients differ from patients of normal w

107 Morbidly obese patients exhibit impaired secretion of gu

108 Morbidly obese patients frequently present with mood and

109 ed' experiences of caring for critically ill morbidly obese patients from the perspectives of intensi

110 Morbidly obese patients had the highest proportion (87%)

111 Physiologically, morbidly obese patients have a higher intraabdominal pre

112 mild obesity have the best survival, whereas morbidly obese patients have the highest mortality.

113 We measured baseline VO(2) in morbidly obese patients immediately prior to gastric byp

114 al and endoscopic options for weight loss in morbidly obese patients including their efficacy and com

115 applying positive end-expiratory pressure in morbidly obese patients is not well defined.

116 Morbidly obese patients may be at increased risk of dela

117 Critically ill morbidly obese patients pose considerable healthcare del

118 size a need for specific protocols to manage morbidly obese patients presenting to the ED with chest

119 bypass has proved to be successful for many morbidly obese patients pursuing weight loss and increas

120 Sixty-six morbidly obese patients randomized to SG or RYGB were in

121 Liver biopsies and serum samples from 113 morbidly obese patients receiving bariatric surgery, hea

122 Morbidly obese patients selected for LRYGB were included

123 Consecutive morbidly obese patients selected for LSG were included i

124 Morbidly obese patients should be considered for BS befo

125 Morbidly obese patients should be considered potential c

126 high-quality disease map for each tissue in morbidly obese patients to not only inform genetic assoc

127 ce following atrial fibrillation ablation in morbidly obese patients to those of nonobese patients.

128 In morbidly obese patients undergoing bariatric surgery, we

129 Morbidly obese patients undergoing laparoscopic bariatri

130 The proportion of morbidly obese patients undergoing PCI increased from 4.

131 Twenty-three morbidly obese patients underwent 1H-magnetic resonance

132 Antrum area during fasting in morbidly obese patients was statistically significant la

133 nteractions between intensive care staff and morbidly obese patients were challenging due to the soci

134 Between May 1999 and March 2001, 155 morbidly obese patients were enrolled in this prospectiv

135 effective for ureteral and renal calculi in morbidly obese patients who are not suitable candidates

136 morbid with morbid obesity were examined for morbidly obese patients who did and did not undergo bari

137 atrial fibrillation ablation in addition to morbidly obese patients who did not undergo BS.

138 tric surgery relative to a control cohort of morbidly obese patients who did not undergo surgery.

139 e studied: morbidly obese patients (n = 16), morbidly obese patients who had had sleeve gastrectomy (

140 We performed Roux-en-Y gastric bypass in two morbidly obese patients who had undergone liver transpla

141 , we compared arrhythmia recurrence rates in morbidly obese patients who underwent prior bariatric su

142 From January 1997 to December 2004, 50 morbidly obese patients with acute respiratory failure w

143 ssistance may influence clinical outcomes in morbidly obese patients with acute respiratory failure.

144 ts apixaban and rivaroxaban, and warfarin in morbidly obese patients with atrial fibrillation and ven

145 1994 through May 2013, one hundred and nine morbidly obese patients with biopsy-proven NASH underwen

146 cDNA from peripheral blood lymphocytes of 22 morbidly obese patients with body-mass index (BMI) betwe

147 Thirty morbidly obese patients with chronic renal failure or tr

148 r than normal weight patients (P=0.073), and morbidly obese patients with computerized tomographic sc

149 In morbidly obese patients with diabetes who were offered D

150 These data suggest that morbidly obese patients with end-stage renal disease who

151 ould be a therapeutic option for appropriate morbidly obese patients with NASH who do not respond to

152 he long-term effects of bariatric surgery in morbidly obese patients with NASH.

153 mproves symptoms and controls reflux in most morbidly obese patients with preoperative GERD.

154 formed a retrospective case-matched study of morbidly obese patients with T2DM who had undergone medi

155 insulin sensitivity and insulin secretion in morbidly obese patients with type 2 diabetes are still u

156 tudinal changes of glucostatic parameters in morbidly obese patients with type 2 diabetes mellitus un

157 nsulin sensitivity and beta-cell function in morbidly obese patients with type 2 diabetes mellitus wh

158 to compare long-term outcomes of 2 groups of morbidly obese patients with type 2 diabetes mellitus-1

159 Morbidly obese patients without computerized tomographic

160 :1 manner with 102 nonobese patients and 102 morbidly obese patients without prior BS on the basis of

161 an-Meier survival was significantly lower in morbidly obese patients, and morbid obesity was an indep

162 For most morbidly obese patients, in addition to causing signific

163 iversion can markedly ameliorate diabetes in morbidly obese patients, often resulting in disease remi

164 were 11% and 29% lower in severely obese and morbidly obese patients, respectively.

165 at Slc27a1 was increased upon weight loss in morbidly obese patients, while Sparc expression was redu

166 blished itself as an effective treatment for morbidly obese patients, with laparoscopic sleeve gastre

167 Ongoing alcohol drinkers and morbidly obese patients, with minimal hepatic injury and

168 A Roux-en-Y gastric bypass was performed in morbidly obese patients.

169 hat covers the entire spectrum of lesions in morbidly obese patients.

170 he standard operation for T2DM resolution in morbidly obese patients.

171 elopment of new health-related conditions in morbidly obese patients.

172 30% lower in severely obese and 38% lower in morbidly obese patients.

173 icantly correlated with AST/ALT ratio in all morbidly obese patients.

174 on of postsurgical elovl6 gene expression in morbidly obese patients.

175 rgeting tongue fat should focus on obese and morbidly obese patients.

176 care setting when caring for critically ill morbidly obese patients.

177 awkward moments were evident when caring for morbidly obese patients.

178 equate for optimal mechanical ventilation of morbidly obese patients.

179 ved insulin resistance pattern compared with morbidly obese patients.

180 body weight and cardiovascular mortality in morbidly obese patients.

181 ban are as effective and safe as warfarin in morbidly obese patients.

182 effective long-term weight loss strategy for morbidly obese patients.

183 roposed clinical scoring can predict NASH in morbidly obese persons with sufficient accuracy to be co

184 system to predict the probability of NASH in morbidly obese persons, thus assisting in the decision t

185 , and 3.45 (95% CI: 2.79, 4.00) for inactive morbidly obese persons.

186 lcoholic steatohepatitis (NASH) is common in morbidly obese persons.

187 Morbidly obese PWH are at risk of presenting suboptimal

188 Morbidly obese recipients experienced a shorter time to

189 4.8% of the nuclear families possessed >or=1 morbidly obese sibling (BMI >or=40).

190 hromatography-tandem mass spectrometry in 29 morbidly obese subjects (13 with diabetes) and 15 nondia

191 Sixty-one morbidly obese subjects (41.7 +/- 0.6 kg/m) with type 2

192 ignificantly higher both in the severely and morbidly obese subjects (P <.05), mostly as a result of

193 We analyzed liver biopsies from 195 morbidly obese subjects after excluding all other causes

194 We exome-sequenced 200 morbidly obese subjects and 100 control subjects with po

195 were endoscopically collected from lean, and morbidly obese subjects before and 3 months after laparo

196 )/F) was elevated approximately threefold in morbidly obese subjects compared with controls (P <.001)

197 Morbidly obese subjects had a selective increase in peri

198 Morbidly obese subjects had lower absolute concentration

199 Morbidly obese subjects had significantly lower MOR avai

200 The peripheral blood T-cell compartment of morbidly obese subjects is characterized by increased ho

201 vated serum or adipose tissue RBP4 levels in morbidly obese subjects may cause hepatic and systemic i

202 and left lobe--in the diagnosis of NAFLD in morbidly obese subjects undergoing bariatric surgery emp

203 e physiologic effects of pneumoperitoneum in morbidly obese subjects undergoing laparoscopy.

204 (SAT), and visceral adipose tissue (VAT) in morbidly obese subjects undergoing Roux-en-Y gastric byp

205 Morbidly obese subjects were enrolled in a single arm, o

206 Cross-sectional study in 18 T2DM morbidly obese subjects who underwent RYGBP but differed

207 2-hour mixed-meal tolerance (MMT) test in 20 morbidly obese subjects with type 2 diabetes who underwe

208 We studied 16 morbidly obese subjects with varying degrees of hepatic

209 Fourteen morbidly obese subjects, 7 with normal glucose tolerance

210 , hepatic CYP2E1 activity is up-regulated in morbidly obese subjects.

211 ICU mortality was lower in morbidly obese than in normal body mass index patients (

212 Waitlist mortality was higher for morbidly obese than normal/overweight patients (subdistr

213 In Latinas, only the morbidly obese were at high risk of death (HR = 2.26, 95

214 The risk in morbidly obese women (BMI > or = 40) was higher (OR: 1.3

215 We studied 13 morbidly obese women [mean body mass index (BMI), 42 kg/

216 Of the 30 morbidly obese women who participated in the study, 21 h

217 as a beneficial effect on symptoms of PFD in morbidly obese women.

218 l history is notable for overweight (but not morbidly obese), hypercholesterolemia, hypertension, cat

219 obese, 1.11 for severely obese, and 1.22 for morbidly obese).

220 relatively safely in the morbidly and super morbidly obese, and does not require a 2-stage procedure

221 o 39.9 kg/m, severely obese; and >/=40 kg/m, morbidly obese, and evaluated waitlist outcomes using co

222 in each of the categories of normal weight, morbidly obese, and post-gastric-bypass surgery.

223 All 3 patients were morbidly obese, and workup revealed underlying cancer in

224 In the morbidly obese, at high minute ventilations, VO(2RESP) i

225 obese, 0.72 for severely obese, and 0.56 for morbidly obese, compared with a reference group of patie

226 Homozygous Cep19-knockout mice were morbidly obese, hyperphagic, glucose intolerant, and ins

227 METHODS AND The db/db mouse is morbidly obese, insulin-resistant, and has tissue-specif

228 Another study showed that, in the morbidly obese, nasal ventilation might be advantageous

229 dies compare surgical patients to a similar, morbidly obese, nonsurgical cohort, especially in high-r

230 reased intra-abdominal pressure, such as the morbidly obese, suffer from a high frequency rate of idi

231 eight, normal weight, overweight, obese, and morbidly obese, were compared using the Kruskall-Wallis

232 As a result, the transgenic mice were morbidly obese, with significantly higher levels of adip

233 gies in this population, particularly in the morbidly obese.

234 ht, 30,259 (28%) as obese, and 9,070 (8%) as morbidly obese.

235 monly experienced with the those who are not morbidly obese.

236 ortance to the critically ill patient who is morbidly obese.

237 ysiologic effects of pneumoperitoneum in the morbidly obese.

238 About 5% of the US population is morbidly obese.

239 nd 3.5% of 38 177 transplanted patients were morbidly obese.

240 tial health benefits for many people who are morbidly obese.

241 patients (66.4%) were overweight, obese, or morbidly obese.

242 merica (overweight: 37.1%, obese: 36.5%, and morbidly obese: 5.8%; P<.001 vs other regions).

243 or demographics and comorbidities, being pre-morbidly overweight (hazard ratio [HR]: 0.72; 95% confid