ライフサイエンスコーパス: morphologic change

1 asses and to follow up masses for growth and morphologic change.

2 tes of surviving large ON-type cells undergo morphologic changes.

3 ort and long half-life proteins and dramatic morphologic changes.

4 in their identification of right ventricular morphologic changes.

5 he development of aneuploidy, and stimulated morphologic changes.

6 ent of RPE cells in vitro results in similar morphologic changes.

7 n 0 and 24 hours, and photographed to detect morphologic changes.

8 ment of lenses with H(2)O(2) caused distinct morphologic changes.

9 ithin tumor cells as opposed to identifiable morphologic changes.

10 r sheath in the CM tips in addition to other morphologic changes.

11 paralleled by miR-375 expression and similar morphologic changes.

12 s distance moved in 2 hours and examined for morphologic changes.

13 ir cells consists of a progressive series of morphologic changes.

14 ting in widespread, although trait-specific, morphologic changes.

15 consistent with the electrophysiological and morphologic changes.

16 isely monitoring the sequence of RPE-related morphologic changes.

17 HFD-induced delay in intestinal transit and morphologic changes.

18 They do not show obvious morphologic changes.

19 nt thermal load should be cognizant of these morphologic changes.

20 ects progressed with time and paralleled the morphologic changes.

21 dy the growth pattern of CNVM and associated morphologic changes.

22 ion, but central corneal DCs assumed extreme morphologic changes.

23 otubule stability is known to underlie these morphologic changes, a mechanism for the loss of presyna

24 s requires that tumor cells undergo dramatic morphologic changes, a process regulated by Rho GTPases.

25 Platelet activation results in profound morphologic changes accompanied by release of granule co

26 o reduced FGF-2 levels and partially blocked morphologic changes after freezing.

27 Among the first morphologic changes after initiation of the apoptotic pr

28 UVR, TNF-alpha, and cis-UCA cause similar morphologic changes among Langerhans cells, which spawns

29 f the transformed phenotype, including fewer morphologic changes, an increase in stress fiber cytoske

30 MT1-MMP-induced morphologic change and cell scattering were abrogated by

31 wn actin regulator, promotes oligodendrocyte morphologic change and myelin production in the CNS.

32 The morphologic change and p21 up-regulation still were obse

33 Forty-eight cancers were assessed for morphologic change and volume doubling time (VDT), which

34 ement was present in the ankle joints, where morphologic changes and abnormal calcification of these

35 These recipient cells display morphologic changes and acquire tumor-associated phenoty

36 st cancer cells was associated with dramatic morphologic changes and actin cytoskeleton remodeling, w

37 hibition of RhoC activity results in drastic morphologic changes and alterations in the expression an

38 nd integrin engagement signals, resulting in morphologic changes and amplified chemotaxis to an other

39 attenuated TGF-beta-induced cytoskeletal and morphologic changes and apoptosis as did treatment with

40 Between groups, morphologic changes and CD3(+) intraepithelial lymphocyt

41 t-passage stromal fibroblast cell death with morphologic changes and DNA fragmentation consistent wit

42 f the K1 gene in rodent fibroblasts produced morphologic changes and focus formation indicative of tr

43 of the R1 gene in Rat-1 fibroblasts induced morphologic changes and focus formation, and injection o

44 Both S91 cells and NHEM exhibit morphologic changes and growth arrest indicative of diff

45 of the CML blast cells occurred as shown by morphologic changes and induction of secondary granule-s

46 oth human and rabbit) demonstrated extensive morphologic changes and inhibition of proliferation when

47 on and antimycin treatment), as evidenced by morphologic changes and internucleosomal DNA cleavage.

48 EMT in MCF10A cells was shown by morphologic changes and loss of E-cadherin/beta-catenin-

49 Morphologic changes and loss of lipid droplets were more

50 No evidence of morphologic changes and no significant difference in the

51 imal hyperplasia associated with endothelial morphologic changes and prominent vascular and perivascu

52 d cell-matrix interaction that is evident by morphologic changes and reduced focal adhesion complex f

53 on prevented H2O2 from inducing mitochondria morphologic changes and reduction of cytochrome b/c.

54 ell invasion that is accompanied by profound morphologic changes and robust reduction in expression l

55 iferation is only partly responsible for the morphologic changes and that other mechanisms such as de

56 Morphologic changes and their relationship to EFL and fa

57 (CT)-determined size, morphology, location, morphologic change, and growth rate of incidence and pre

58 to 14 days resulted in proliferative arrest, morphologic changes, and apoptosis characteristic of cel

59 criptionally distinct, underwent significant morphologic changes, and displayed unique activation sig

60 ectron microscopy was applied to demonstrate morphologic changes, and Safranin O staining was perform

61 HMEC-E6 cells as evidenced by characteristic morphologic changes, annexin V binding, and DNA fragment

62 -treated PR transfectants showed significant morphologic change, appearing more flattened and spread

63 These morphologic changes are associated with an elevated tryp

64 These morphologic changes are associated with an elevated tryp

65 atients and to determine whether distinctive morphologic changes are associated with mutations in thi

66 ich clarify their pathogenesis and attendant morphologic changes are highlighted.

67 EOM morphologic changes are highly correlated with degrees o

68 to Purkinje cells, neuronal dysfunction and morphologic changes are observed without the formation o

69 roughness, surface contraction, and stromal morphologic changes are supportive of this interaction.

70 se hydrodynamic changes are likely driven by morphologic changes associated with AP collapse and hern

71 s and/or substrates that are relevant to the morphologic changes associated with cell division.

72 expression of the monocytic marker CD14 and morphologic changes associated with differentiation.

73 ng technique for visualizing and quantifying morphologic changes associated with experimental laser-i

74 ociated renal injury and late functional and morphologic changes associated with the interval of dono

75 We hypothesized that the distinct cellular morphologic changes associated with treatment-induced ap

76 The primary outcome was the frequency of morphologic changes at MRI.

77 Sequential outer retinal morphologic changes at the FTMH borders occurred in 4 di

78 8S) ) in Drosophila motor neurons results in morphologic changes at the larval neuromuscular junction

79 ntitative assessment of signal intensity and morphologic changes before and after UAE.

80 by pro-HB-EGF not only resulted in cellular morphologic change but also decreased cell motility and

81 t kidneys, overexpression of CCN3 induced no morphologic changes but regulated glomerular gene transc

82 levels of H(2)O(2) (0.5 mM) induced similar morphologic changes, but sooner (within 1 hour) and more

83 cohort, suggesting treatment-related kidney morphologic changes, but was not observed in the pretarg

84 phosphate (PARP), and examination of nuclear morphologic changes by Hoechst DNA nuclear staining and

85 interval was adjusted mainly on SD-OCT based morphologic changes by increasing or reducing in 2-week

86 anifestations and often with mild glomerular morphologic changes by light microcopy.

87 and its treatment with meibomian gland (MG) morphologic changes by standardized meibography.

88 , and to promote EMT-like changes, including morphologic changes, cell migration, and invasion.

89 markers and the formation of round cells, a morphologic change characteristic of EHT.

90 Morphologic changes characteristic of apoptosis were ind

91 viability of dendritic cells accompanied by morphologic changes characteristic of autophagy and imma

92 detectable leukotoxin failed to exhibit the morphologic changes characteristic of cells undergoing a

93 the VEGFR-1 ligands VEGF-A and VEGF-B led to morphologic changes characteristic of EMT, including los

94 m ionophore (CI), but not CI alone exhibited morphologic changes characteristic of mature DCs and exp

95 ischemia and reperfusion caused significant morphologic changes characterized by loss of villus epit

96 amic process characterized by phenotypic and morphologic changes concomitant with increased migratory

97 Ultrastructural morphologic changes consistent with apoptosis were obser

98 linically viable methodologies either detect morphologic changes (CT/ MR), recruitment of immune cell

99 elsolin may be one physiological effector of morphologic change during apoptosis.

100 Physical forces generated by cells drive morphologic changes during development and can feedback

101 lular functions, including cell motility and morphologic changes during differentiation.

102 dult zebrafish retina and reveal the dynamic morphologic changes during either light-induced damage a

103 Hsp27 may participate in morphologic changes during granule-mediated lysis.

104 tions result in dominant gene regulatory and morphologic changes during iPSC-neuronal differentiation

105 angiography can depict intracranial vascular morphologic changes during treatment of brain metastases

106 roscopic analyses were performed to evaluate morphologic changes, ER stress, and autophagy.

107 ransformation of NIH 3T3 cells, resulting in morphologic changes, focus formation, and growth in redu

108 asive phenotypes, including the induction of morphologic changes from the epithelial-to-mesenchymal t

109 produces adverse effects including cellular morphologic changes, growth rate attenuation and alterat

110 Metabolic and morphologic changes have been described in patients with

111 ility by inducing apoptosis, as indicated by morphologic changes, histologic evidence of nuclear cond

112 Nonspecific morphologic changes, however, were the most common histo

113 c expression of Tiam1 in these clones led to morphologic changes identical to biologically selected c

114 on was observed well before the detection of morphologic change in both the lens and the retina.

115 However, a dose-dependent morphologic change in disorganization of the subplate wa

116 yoblast transfectants exhibited a pronounced morphologic change in response to exogenous FGF-1.

117 eriodontitis induction, there was no obvious morphologic change in the periodontium, although slight

118 th collagen- and vitreous-treatment caused a morphologic change in the RPE cells to a more fibroblast

119 SD-OCT scans were qualitatively assessed for morphologic changes in 19 patients.

120 al subclassifications based on molecular and morphologic changes in a cell's response to that injury

121 activation of the K-ras oncogene and display morphologic changes in alveolar epithelial cells that re

122 bility to help assess the presence of subtle morphologic changes in bone and bone marrow edema, dual-

123 The observed morphologic changes in bovine leukocytes were leukotoxin

124 electron microscope demonstrated significant morphologic changes in cells perfused with all concentra

125 The potential of ACEA 1021 to produce morphologic changes in cerebrocortical neurons of the ra

126 ach had different effects on CT angiographic morphologic changes in coronary atherosclerosis over 4 y

127 mechanisms by which calcium signals lead to morphologic changes in dendrites are not well understood

128 One signal, BMP4, has been shown to induce morphologic changes in dental mesenchyme and mesenchymal

129 emonstrated to regulate cortical actin-based morphologic changes in Dictyostelium and the oxidative b

130 levels of ethanol that did not cause obvious morphologic changes in either the body or retina did aff

131 Functional and morphologic changes in extracranial organs can occur aft

132 Although no significant morphologic changes in glomeruli were observed in these

133 n also detect and define the hemodynamic and morphologic changes in HF over time and might be equival

134 sforming growth factor beta1 induce profound morphologic changes in immature articular cartilage.

135 mor regression in the absence of significant morphologic changes in kidney, liver, or heart.

136 5(OH)(2)D levels are associated with adverse morphologic changes in large arteries, and this may be m

137 Exudate evoked morphologic changes in macrophages in vitro like that of

138 e find that the onset of paralysis parallels morphologic changes in motor neuron cell bodies in the l

139 k of replication, high doses of mCMV induced morphologic changes in neurons and glia from hamster and

140 Exercise training (ET) causes functional and morphologic changes in normal and injured brain.

141 sis of bone metastasis; however, CT revealed morphologic changes in only half of the lesions assigned

142 ducts may be associated with transient gross morphologic changes in oral soft tissues.

143 No morphologic changes in osteoblasts were observed, and bo

144 -EVs reduce injury-related physiological and morphologic changes in perilesional layer 3 pyramidal ne

145 r, it has been shown that astrocytes undergo morphologic changes in response to brain metastasis, swi

146 HLFs underwent major morphologic changes in response to chymase, showing sign

147 tters), a finding supported by more advanced morphologic changes in right eyes.

148 Morphologic changes in specific cell populations were ev

149 ting mAb, designated 3E2, elicited prominent morphologic changes in sporozoites and merozoites charac

150 Purified BFT causes striking morphologic changes in subconfluent human colonic epithe

151 ly E11-14, which coincides with the onset of morphologic changes in telencephalic RG; (2) at E15-16,

152 Morphologic changes in the cells were also examined.

153 Ciliary body PDT resulted in morphologic changes in the ciliary body, significant red

154 id (FA) synthesis causing chronic stress and morphologic changes in the ER.

155 iod including increased serum creatinine and morphologic changes in the graft including interstitial

156 binding activity and resulted in remarkable morphologic changes in the heart of the transgenic mice.

157 type III LTPs produced microscopy-observable morphologic changes in the intine underneath the exine (

158 atency and intrahepatic portal branches, the morphologic changes in the liver, the presence of hepati

159 Imaging of DeltaPsi(m) revealed morphologic changes in the mitochondria after depolariza

160 al, and treatment factors were compared with morphologic changes in the optic disc microvasculature.

161 omprehensive cross-sectional analysis of the morphologic changes in the peritoneal membranes of patie

162 Initial morphologic changes in the process of cell death were cy

163 hat gonadal hormonal manipulation results in morphologic changes in the rat hippocampus.

164 s suggest that OCT can detect functional and morphologic changes in the retina of carriers of familia

165 n did not reveal any overt toxicity or gross morphologic changes in the retina.

166 Morphologic changes in the retinal pigment epithelium (R

167 polarization-sensitive OCT revealed specific morphologic changes in the RPE and outer retinal layers

168 Morphologic changes in the small intestine and colon wer

169 Loss of receptor resulted in morphologic changes in the stroma, including changes in

170 ortisol acetate showed steroid glaucoma-like morphologic changes in the TM that correlated with the i

171 ence and immunohistochemical analyses imaged morphologic changes in the tumor blood-brain barrier mic

172 y and vascular permeability may occur before morphologic changes in the vasculature.

173 so for the first time, that the longitudinal morphologic changes in these structures are behaviorally

174 in activated microglia (increased number and morphologic changes) in the periventricular region and h

175 induced a dose-dependent gradual increase in morphologic changes; in contrast, EPO and EDN induced mi

176 A resulted in increases in sphingomyelin and morphologic changes including increased epidermal lipid

177 Morphologic changes, including morphologic patterns, and

178 s prepared for transplantation undergo rapid morphologic changes, including retraction of axon termin

179 that the exogenous MUC13 expression induced morphologic changes, including scattering of cells.

180 Various morphologic changes, including whitening of the treated

181 t that reduced expression of PDEF leads to a morphologic change, increased migration and invasiveness

182 inal granulocytic differentiation, including morphologic changes, increased CD11b/CD66b expression, a

183 l cord microglia response marked by dramatic morphologic changes, increased production of IL-1, and e

184 These functional and morphologic changes indicate the development of nephroti

185 tificial surfaces, underwent biochemical and morphologic changes indicative of a potentiated state, i

186 hese cells Fas oligomerization triggered the morphologic changes indicative of apoptosis regardless o

187 alyzes exchange for RhoA, but does not cause morphologic changes indicative of RhoA activation.

188 The HCT-8 organoid displayed morphologic changes indicative of successful and quantif

189 hibitor decreased cell viability and induced morphologic changes indistinguishable from those caused

190 activity and the increased proliferation and morphologic change induced by TGF-beta in vitro.

191 ect than wild-type PAK5, indicating that the morphologic changes induced by PAK5 are directly related

192 The morphologic changes induced by reduction of blood flow w

193 f the KCL22 blast cells occurred as shown by morphologic changes, induction of expression of CD11b, p

194 surface of transfected cells, and that this morphologic change is similarly PH domain dependent.

195 This morphologic change led to the excision of the lesion.

196 Visual acuity and morphologic changes measured on SD-OCT.

197 ular matrix-derived signals lead to critical morphologic changes mediated through cytoskeletal rearra

198 The morphologic changes most likely reflected interference o

199 ithelial cells (podocytes) undergo extensive morphologic changes necessary for creation of the glomer

200 that modulation of activity may play in the morphologic changes observed after reducing cortical 5-H

201 ed by cell viability, DNA strand breaks, and morphologic changes observed by transmission electron mi

202 ut mice from birth until 3 wk, preceding the morphologic changes observed in the hair follicles.

203 phenol in human melanocytes, as well as with morphologic changes observed in this study in cells expo

204 The molecular and morphologic changes observed in young BBS animal model e

205 However, distinct morphologic changes occur with injury that appear to com

206 However, the morphologic changes occurring in response to BFT are dep

207 6, and 18 h in culture, and examined for the morphologic changes of apoptosis and viability by fluore

208 strand breaks, a later step in a sequence of morphologic changes of apoptosis process.

209 tivation, DNA fragmentation, and the classic morphologic changes of apoptosis.

210 n death in male mice accompanied by loss and morphologic changes of cardiac mitochondria and down-reg

211 IVCM reveals an increased density and morphologic changes of central epithelial DCs in infecti

212 Morphologic changes of concern for neoplasm were present

213 d constitutively activated Mek or Erk showed morphologic changes of differentiation.

214 Typical morphologic changes of ER stress preceded development of

215 Apoptosis was assessed hourly by nuclear morphologic changes of fixed cells by DAPI fluorescence

216 ter transplantation and were associated with morphologic changes of focal segmental glomerulosclerosi

217 This study examines morphologic changes of glial cells in the retinas of gla

218 To examine whether S1P contributes to the morphologic changes of islets via S1P2, the receptor ant

219 Ectopic expression of TMEM106B induces morphologic changes of lysosome compartments and delays

220 permeability, vascular lesions, leukostasis, morphologic changes of micro- and macroglia, apoptosis,

221 NOS, caspase-1 as well as the activation and morphologic changes of microglia in the absence of any b

222 atment significantly reduced the severity of morphologic changes of OA compared with placebo.

223 with and without TGF-beta1 inhibitor, on the morphologic changes of primary culture of hGE cells were

224 into the axonal density and macrostructural morphologic changes of the acoustic radiation in hearing

225 The angle and morphologic changes of the PCL are age dependent through

226 Morphologic changes on CT scans were visually assessed b

227 vity within an inflamed arterial wall before morphologic changes on other imaging studies.

228 diation creates a characteristic spectrum of morphologic changes on the porcine corneal stromal surfa

229 Abs' kidney retention with no observation of morphologic changes on therapy regimen at early time poi

230 teristics such as the presence or absence of morphologic changes or accompanying findings (including

231 Simvastatin did not cause morphologic changes or cytotoxicity in the fibroblasts,

232 cular weight polymer (83 kDa) did not induce morphologic changes or inflammatory responses in the bla

233 veforms, and their retinas had no detectable morphologic changes or loss of cells.

234 ction, recipients developed proteinuria with morphologic changes (podocyte effacement), a condition t

235 The p38 inhibitor blocked only the morphologic changes produced by TNFalpha.

236 photosensitizers that elicits no significant morphologic changes produces transient and recoverable r

237 after BI, there were non-significant nuclear morphologic changes reflecting a transition to a rounder

238 emory T cell and alloantibody response, with morphologic changes reflecting antibody-mediated allogra

239 esulted in the epithelial-to-fibroblast-like morphologic changes reported by others and in the decrea

240 modifications drive the distinct programmed morphologic changes required for tissues to mature into

241 The metabolic and morphologic changes resulting from activation of the str

242 d outer nuclear membranes reminiscent of the morphologic changes seen in cells productively infected

243 ulation appears closely related to the other morphologic changes seen in patients with EoE.

244 In our series, we attempted to analyze the morphologic changes seen in the optic disc pit and evalu

245 stly, we demonstrate partial reversal of the morphologic changes seen within the afferent IHC ribbon

246 cells undergo an aging program that includes morphologic changes, sterility, redistribution of the Si

247 c protein 26 (MIP26), CP49, and filensin and morphologic changes such as cell multilayering and elong

248 The proportion of patients showing retinal morphologic changes, such as intraretinal cysts (IRCs),

249 al changes coupled with a lack of detectable morphologic changes suggest that ANT1 is not essential f

250 h after ischemic stroke (IS) indicates glial morphologic changes, suggesting that active inflammation

251 ssays were used to confirm the nature of the morphologic changes that accompany growth factor stimula

252 th primary myelofibrosis show functional and morphologic changes that are associated to the mesenchym

253 ows for an examination of the retina's early morphologic changes that are not generally visible with

254 Astrocytes in the glial lamina showed morphologic changes that correlated with the severity of

255 c deletion of Klf5 in adult mice resulted in morphologic changes that included a regenerative phenoty

256 plementary information about biochemical and morphologic changes that occur during the development of

257 Morphologic changes that occur with deletion of Klf5 are

258 sequestration, induced immunophenotypic and morphologic changes that paralleled CI treatment.

259 ma xenografts exhibit increased invasion and morphologic changes that resemble human large cell anapl

260 ular necrosis does not actually manifest the morphologic changes that the name implies.

261 G waveforms during ischemia exhibited severe morphologic changes, the algorithm-determined RRs exhibi

262 , Schiff reagent, and fluorescein, to assess morphologic changes, the presence of goblet cells, and b

263 ccumulation, even at doses too low to effect morphologic changes; the initial (first 48 hours), gradu

264 the time course of chemotherapy and precede morphologic changes, these results suggest that the APT

265 Tooth germs undergo a series of dynamic morphologic changes through bud, cap, and bell stages, i

266 HIV/SIV infection in spleen and in promoting morphologic changes through the loss of specific macroph

267 The morphologic changes, time of onset, and percentage of an

268 proximal femur was used to determine whether morphologic changes to the bone could be quantified and

269 optosis in hRPE, indicated by characteristic morphologic changes; TUNEL-positive labeling; phosphatid

270 All dogs showed gross morphologic changes typical of OA in the unstable knee.

271 tem make it a likely candidate for mediating morphologic changes typically seen in the epileptic hipp

272 enic patients to determine whether there are morphologic changes underlying these cognitive deficits.

273 ressing Box3-deficient gp130 showed distinct morphologic changes upon receptor activation.

274 rding to areas defined by biomarker-specific morphologic changes using Bland-Altmann coefficients of

275 Interobserver agreement for scoring morphologic changes was good among 3 radiologists (kappa

276 Cell morphologic changes were accompanied by decreased epithe

277 These noladin ether-induced morphologic changes were also blocked by SR141716A and P

278 Morphologic changes were assessed before and after anti-

279 At day 21, morphologic changes were assessed by immunohistochemistr

280 Morphologic changes were assessed by light microscopy at

281 In neurons that were dying by apoptosis, morphologic changes were characterized by a highly order

282 These morphologic changes were closely correlated with a decre

283 Morphologic changes were completely inhibited by treatme

284 as 0.5 pM could also cause intoxication, but morphologic changes were detectable only when the assay

285 dystrophic, with disrupted lens, whereas no morphologic changes were detected in the eyes of the oth

286 Cellular morphologic changes were evaluated by electron microscop

287 These morphologic changes were independent of hTR expression a

288 Morphologic changes were observed in photoreceptor sheet

289 f plasminogen and plasminogen activator, and morphologic changes were observed using scanning electro

290 These morphologic changes were partially reversed by RbAp48 kn

291 Lens histologic and morphologic changes were recorded microscopically.

292 No RD and minimal morphologic changes were seen in the eyes injected with

293 The functional and morphologic changes were studied chronologically (from 1

294 latelets undergo a series of actin-dependent morphologic changes when activated by thrombin receptor

295 ted with the B. fragilis toxin (BFT) develop morphologic changes with dissolution of tight clusters a

296 to E8.5), when the conceptus undergoes rapid morphologic changes with formation of the yolk sac and b

297 ysis revealed Pten/Kdm5b mice displayed mild morphologic changes with hyperplasia in prostates, where

298 mplete media to nonselective media displayed morphologic changes with static growth.

299 face contracted and underwent characteristic morphologic changes with the applied thermal load, which

300 Gene expression profiles parallel cell-morphologic changes with time, ultimately leading to inc