ライフサイエンスコーパス: motile

1 Many species are also motile(9), which is studied in terms of mechanism(10,11)

2 ttle effect on the actin-activated ATPase or motile activities of Myo1c.

3 s to regulation of NSCLC cell morphology and motile activity.

4 he development of this response mechanism in motile algae may have been an important step in the evol

5 s responses, with some cells becoming highly motile and a fraction of HSCs expanding clonally within

6 single cells reseeded onto micro-discs were motile and aggregated with the same but segregated from

7 Rods are motile and capable of dissemination.

8 The neckless tails were motile and could induce capacitation but had no signific

9 is achieved in environments where cells are motile and dispersed among their progeny remains unknown

10 DOCK5 has a non-redundant role in regulating motile and invasive capacities of epithelial cells.

11 r growth but rendered transformed cells more motile and invasive in a manner dependent on ROS-mediate

12 n of PhIL1, an IMC-associated protein on the motile and invasive stages of both human and rodent para

13 Here we demonstrate, with the use of motile and isogenic nonmotile deletion mutants of two in

14 thermore, we show that gammadeltaT cells are motile and locate preferentially in the epithelium adjac

15 cular microglia within the cortex are highly motile and migrate along vessels as they are colonizing

16 ld-type cells, TRPC6(-/-) podocytes are less motile and more adhesive, with an altered actin cytoskel

17 genic properties; coccoid C. jejuni were non-motile and non-infectious, with minimal adherence and in

18 tructures in a colony grown from mixtures of motile and non-motile bacterial species on a soft agar s

19 undaries between the fluid dynamic niches of motile and non-motile phytoplankton, and highlights that

20 an important cause of the succession between motile and non-motile species when conditions turn turbu

21 18 expression facilitates the uptake of both motile and nonmotile P. aeruginosa However, unexpectedly

22 t PAM is required for the normal assembly of motile and primary cilia in Chlamydomonas, planaria and

23 ic switching of SMCs from a contractile to a motile and proliferative phenotype and is responsible fo

24 t metastasis is a selective process favoring motile and softer cells.

25 w that intracellular signals are observed in motile and stabilized "ectopic" contacts.

26 The highly motile and versatile protozoan pathogen Trypanosoma bruc

27 namic nature of mechanically reconfigurable, motile, and explosive crystals.

28 les gradually become fertile as sperm become motile, and that oviposition behavior increases sharply

29 Oxygen is a prerequisite for all large and motile animals.

30 - has obvious importance for the survival of motile animals.

31 d play a key role in the clearance of highly motile apoptotic neutrophils during the resolution phase

32 We show that dimeric motors, with a motile arm on only one of the two MTs, produce large pol

33 MT clusters, whereas tetrameric motors, with motile arms on both microtubules, produce bundles.

34 Motile arrest after YAP/TAZ ablation was partially rescu

35 Members of this phylum are frequently motile as well.

36 les display decreased nematic order and that motile asters distort the nematic director field.

37 rectly visualize DNA lesion search by highly motile ATL and ATL-UvrA complexes on DNA at the molecula

38 Time-lapse imaging shows that non-motile bacteria 'hitchhike' on the motile bacteria as th

39 The non-motile bacteria accumulate at the boundary of the colony

40 ferent microrobots, ranging from tailor-made motile bacteria and tiny bubble-propelled microengines t

41 Non-motile bacteria are more immunogenic due to a lower expr

42 Motile bacteria are proficient at finding optimal enviro

43 Most motile bacteria are propelled by rigid, helical, flagell

44 that non-motile bacteria 'hitchhike' on the motile bacteria as the latter migrate outward.

45 natural environments with limited nutrients, motile bacteria can actively migrate towards locations o

46 Motile bacteria exhibit a variety of motility patterns,

47 Here, we report a new method to sequester motile bacteria from a liquid, based on passive, deploya

48 t the colonization of non-planar surfaces by motile bacteria is largely controlled by flow.

49 How motile bacteria move near a surface is a problem of fund

50 Most motile bacteria possess at least one CheY response regul

51 Motile bacteria remodel the host plasma membrane into pr

52 Motile bacteria sense chemical gradients with transmembr

53 -associated gut microbiotas is enrichment of motile bacteria, which can facilitate microbiota encroac

54 ced biosensing platform for the detection of motile bacteria.

55 s are not motile themselves, they can infect motile bacterial hosts and spread in space via the hosts

56 colony grown from mixtures of motile and non-motile bacterial species on a soft agar surface.

57 ort to describe the expansion of both highly motile bacterial swarms, and sessile bacterial biofilms.

58 As a motile bacterium approaches and adheres to a surface fro

59 on through a single effector in this surface-motile bacterium.

60 regenerate zone comprising pObs and adjacent motile basal epidermal cells.

61 t macrophages were sessile, whereas DCs were motile before and after inflammation.

62 Surprisingly, we found that Vibrio's motile behavior does not enhance its growth rate but rat

63 r straight or circular trajectories, and the motile behavior is sensitive to conditions at the cell b

64 kinase A (PKA) activity is important for the motile behavior of many cell types, yet the mechanisms g

65 Additionally, the motile behaviors of hcn plasmids provide quantitative es

66 sted different models involving differential motile behaviours with or without biases due to neighbou

67 cells (OHCs), which possess both sensory and motile capabilities.

68 ion acts as a molecular compass that orients motile cell polarity and spatially directs tissue moveme

69 Image analysis of motile cell populations, both primary and cultured, typi

70 s with actin at the cellular leading edge of motile cells and suppresses FAK.

71 ly inhibited, as measured by the fraction of motile cells and the mean invasion depth.

72 controlling IF dynamics and organization in motile cells are still poorly understood.

73 imarily infects T lymphocytes and uses these motile cells as migratory vehicles for effective dissemi

74 sis, and many other multicellular phenomena, motile cells group into a collective and migrate persist

75 Motile cells have developed a variety of migration modes

76 Here, we show that motile cells in sessile colonies of peritrichously flage

77 Compared with unsorted cancer cells, highly motile cells isolated by the device exhibited similar tu

78 Escherichia coli to an antibiotic to obtain motile cells of different lengths, and characterized the

79 Lymphocytes are some of the most motile cells of vertebrates, constantly navigating throu

80 time, with particular promise for studies of motile cells or interlinked networks not easily analyzed

81 However, many motile cells rely on both signaling modules and actin cy

82 RNA sequencing of the highly motile cells revealed an enrichment of motility-related

83 RNA sequencing of the highly motile cells revealed differentially expressed genes tha

84 cells form loose, intravascular clusters of motile cells that coalesce around portal tracts.

85 Macrophages are motile cells that roam the extracellular spaces within o

86 The asymmetric 3D micro-structure promotes motile cells to swim from outside the cage towards the i

87 Despite being made up of motile cells, germinal centres are tightly confined with

88 flagellar thrust force and swimming speed of motile cells.

89 and by promoting rapid surface attachment of motile cells.

90 ehavior and play role in selection of highly motile cells.

91 bind actin networks at the front or rear of motile cells.

92 tory disorder reduced generation of multiple motile cilia (RGMC), have implicated the nuclear protein

93 w is generated locally by caudally-polarized motile cilia along the ventral wall of the central canal

94 basal foot proteins in cells with primary or motile cilia and discover a hybrid cilium with a unique

95 e nexin-dynein regulatory complex (N-DRC) in motile cilia and flagella functions as a linker between

96 moving essential body fluids and molecules, motile cilia and flagella govern respiratory mucociliary

97 glycylation has so far been mostly found on motile cilia and flagella, where it is involved in the s

98 In motile cilia and flagella, which drive cell locomotion a

99 hybrid cilium emerges independently of other motile cilia and functions in regulating basal body alig

100 highlight the architectural differences with motile cilia and provoke a reassessment of the relations

101 Motile cilia are cellular beating machines that play a c

102 Motile cilia are found on unicellular organisms such as

103 Motile cilia are hairlike structures that line the respi

104 Motile cilia are highly complex hair-like organelles of

105 We also found that the motile cilia are polarized coordinately and display a pl

106 During multiciliated cell differentiation, motile cilia are templated from basal bodies, each exten

107 Motile cilia are widespread across the animal and plant

108 These findings provide new insights into motile cilia biology and may lead to novel ciliopathy tr

109 Impaired function of motile cilia causes failure of mucociliary clearance.

110 Nearly all motile cilia contain a central apparatus (CA) composed o

111 However, motile cilia could sense their own motion by a yet unkno

112 iary dyskinesia (PCD), a condition caused by motile cilia defects.

113 e also demonstrate that at this early stage, motile cilia ensure the proper formation of the central

114 volutionarily conserved protein required for motile cilia function and linked to a common form of inh

115 nd genetic mechanisms regulating the CPA and motile cilia function.

116 Nearly all motile cilia have a "9+2" axoneme containing a central a

117 tissue, ZikV-NS5 persists at the base of the motile cilia in ependymal cells, which also exhibit a se

118 e we set out to define genes associated with motile cilia in humans based on their transcriptional si

119 ment and also contribute to the formation of motile cilia in the soma.

120 with structural features of both primary and motile cilia is harbored.

121 ich ODAs are recognized and transported into motile cilia is still unclear.

122 The axoneme of motile cilia is the largest macromolecular machine of eu

123 or, and the autophagy-mediated regulation of motile cilia length via kinesin Kif19a, a regulator of c

124 Here, we demonstrate that among the many motile cilia of a multiciliated cell, a hybrid cilium wi

125 ceptor protein robustly localizes within the motile cilia of airway epithelial cells, which likely re

126 Motile cilia on multiciliated cells (MCCs) function in f

127 Motile cilia power cell locomotion and drive extracellul

128 In the airways, hundreds of motile cilia present on the surface of a multiciliated e

129 BSome, transition zone, ciliary membrane and motile cilia proteins.

130 Motile cilia provide propulsion, and immotile ones are e

131 specialized epithelia with apical bundles of motile cilia that direct fluid flow.

132 These cells are multiciliated, with motile cilia that play key physiological roles.

133 Cells use motile cilia to generate force in the extracellular spac

134 extending a basal foot-an appendage linking motile cilia together to ensure coordinated beating.

135 ulticiliated cells (MCC) contain hundreds of motile cilia used to propel fluid over their surface.

136 Decreased density and structural defects of motile cilia were observed in the epidermis of Smed-TTBK

137 he ciliopathy reduced generation of multiple motile cilia with mutations in MCIDAS and CCNO.

138 In motile cilia, a mechanoregulatory network is responsible

139 onserved modular architecture in primary and motile cilia, but showing distinct features reflecting i

140 iption factors important for ciliogenesis of motile cilia, cause a motile ciliopathy that is characte

141 kinesia (PCD) originates from dysfunction of motile cilia, causing symptoms such as chronic sinusitis

142 along and out of the lung by the activity of motile cilia, expelling at the same time particles trapp

143 Motile cilia, hairlike structures present on the cell su

144 s throughout the mammalian brain possess non-motile cilia, organelles with varied functions in sensor

145 In summary, we report a set of motile cilia-associated genes that helps shape our under

146 For each tissue, genes coexpressed with the motile cilia-associated transcriptional factor, FOXJ1, w

147 Symmetry is broken by motile cilia-generated asymmetric fluid flow, resulting

148 iopathic-like scoliosis to irregularities in motile cilia-mediated cerebrospinal fluid flow [7-9].

149 of basal bodies, and synchronized beating of motile cilia.

150 rized and coordinated beating of hundreds of motile cilia.

151 ulating dynein-driven microtubule sliding in motile cilia.

152 y be more complicated than that reported for motile cilia.

153 s, which are required for producing multiple motile cilia.

154 oxj1a is necessary and sufficient to specify motile cilia.

155 eneous syndrome that results from defects in motile cilia.

156 ted signaling mechanism regulating growth of motile cilia.

157 ine receptors (Drd1), which are expressed in motile cilia.

158 gnature consistent with it playing a role in motile ciliary assembly or activity.

159 Decreased PAM gene expression reduced motile ciliary density on the ventral surface of planari

160 kely targetable signaling axis that controls motile ciliary function in humans and has potential impl

161 specific kinase whose activity regulates the motile ciliary proteome to promote ciliary length and mu

162 se claims were based on experiments with the motile ciliate Stentor coeruleus.

163 ptomics data derived from tissues possessing motile ciliated cell populations.

164 al stem cells, mucus-secreting goblet cells, motile ciliated cells, cystic fibrosis transmembrane con

165 and the localisation of mRNA and proteins in motile ciliated cells.

166 ent and redundant function in the control of motile ciliogenesis in mice.

167 in this process and most genes required for motile ciliogenesis.

168 ssociated with basal bodies during and after motile ciliogenesis.

169 at impair ciliary beating cause a variety of motile ciliopathies, a heterogeneous group of rare disor

170 Motile ciliopathy can result from defects in the dyneins

171 (CFAP45) in humans and mice that presents a motile ciliopathy featuring situs inversus totalis and a

172 ed an autosomal-dominant cause of a distinct motile ciliopathy related to defective ciliogenesis of t

173 nt for ciliogenesis of motile cilia, cause a motile ciliopathy that is characterized by hydrocephalus

174 No single test can confirm a diagnosis of motile ciliopathy, which is based on a combination of te

175 primary ciliary dyskinesia, the most common motile ciliopathy.

176 provide the highest-resolution images of the motile cilium to date and reveal how BBs template axonem

177 muscle cells going from a proliferative and motile circular shape to a contractile fusiform shape sh

178 Twenty-one small Gram-negative motile coccobacilli were isolated from 15 systemically d

179 ive liquid crystals or chemically engineered motile colloids.

180 join dynein and its cofactor dynactin into a motile complex and (b) interact with a cargo-bound recep

181 Lis1 dissociates from motile complexes, indicating that its primary role is to

182 ~75 mm in diameter), deformable, and highly motile, complicating long-term imaging and limiting stud

183 on with an extensive morphological survey of motile curved-rod bacteria indicates that the vast major

184 Motile DDB complexes bound up to two LIS1 dimers, and mu

185 2 mutants showed an enhanced ability to form motile DDB complexes.

186 ng, two crabs can compete and fight over the motile, diffusiophoretic particles.

187 is the switch between biofilm formation and motile dispersal, and this dynamic is well illustrated i

188 nctions in multiple stages of assembling the motile dynein-dynactin-activating adaptor complex.

189 all external perturbation in a dense bath of motile E. coli bacteria.

190 Motile endolysosomes contact nascent phagosomes to promo

191 ranslation-depolarised filopodia dynamics in motile endothelial cells and induced mispatterning of bl

192 cium levels are high in immotile compared to motile epididymal sperm.

193 not clear whether the ER is remodeled during motile events to localize calcium signals in steering gr

194 teractions and production of the cancer cell motile factor RANKL.

195 the actinomycete genus Streptomyces are non-motile, filamentous bacteria that are well-known for the

196 nated polar accumulation of PilA on cells in motile filaments, while the Ptx system controls positive

197 with episodic Ca(2+) signals present in both motile filopodia as well as in later-stabilized synaptic

198 Most motile flagella have an axoneme that contains nine outer

199 Many bacteria cycle between sessile and motile forms in which they must sense and respond to int

200 al proliferation in the vertebrate host, and motile free-living stages.

201 where they have sensory, developmental, and motile functions.

202 or host control of Pseudomonas aeruginosa, a motile Gram-negative, opportunistic bacterial pathogen w

203 cal modeling to explore how phages and their motile host bacteria coexist and co-propagate.

204 When lytic phages encountered motile host bacteria in our experimental set up, a secto

205 n spirotrich ciliates, which is a localized, motile hub that traverses the macronucleus while replica

206 ganisms, from transient interactions between motile immune cells to long-lived cell-cell contacts in

207 flow of cortex and also that lymphocytes are motile in nonadherent confined environments.

208 However, cells are still motile in the mutants where MglA localizes symmetrically

209 ulation of mitochondria - via encounter with motile intracellular pathogens, via external pressure ap

210 The conserved non-motile kinesin Kif7 defines a "cilium-tip compartment" b

211 ratocytes, which are essentially stand-alone motile lamellipodia.

212 Upon starvation, JMY shifts to motile, LC3-containing membranes that move on actin come

213 Motile male gametes (sperm cells) are an ancestral eukar

214 gans EFHC-1 functions within specialized non-motile mechanosensory cilia, where it regulates neuronal

215 Throughout vertebrate trunk elongation, motile mesodermal progenitors undergo an order-to-disord

216 ntiation of epithelial tumor cells towards a motile, metastatic, and mesenchymal tumor phenotype, med

217 materials possess the required features for motile micro- and nanodevices, such as high cargo-loadin

218 coveries and innovative concepts realized in motile micro- and nanostructures have converged in the f

219 imulus-response behaviors in biology wherein motile microorganisms sense light gradients to swim towa

220 action to light displayed by a wide range of motile microorganisms.

221 towards smart liquid dispersions comprising motile microscale objects.

222 A multifunctional motile microtrap is developed that is capable of autonom

223 RTKS and EPS8 localize to the barbed ends of motile microvilli, where they control the kinetics and n

224 n this review pave the way toward the use of motile MOFs for a variety of applications in the fields

225 ubfertility, respectively, and malfunctional motile monocilia of the left-right organizer during earl

226 Deletion of fliD leads to non-motile mutant cells that are unable to assemble flagella

227 Given our observation that a non-motile mutant, in which proton flux is blocked, cannot g

228 used by a 6-fold decrease in the fraction of motile NK cells after cryopreservation.

229 ilm-forming bacteria that are rod-shaped and motile on soft surfaces exhibit polymertropism.

230 ese originally stationary cells readily turn motile on the uniform TGT surface, and their motility is

231 recombination leads to normal development of motile ookinetes that exhibit a severely impaired capaci

232 nutrient poor, hyphal osmotrophs outcompete motile or autolytic unicellular osmotrophs.

233 ace of many eukaryotic cell types and can be motile or non-motile primary cilia.

234 presented here to study a variety of large, motile organisms.

235 To proliferate, non-motile parasites must have access to susceptible red blo

236 The coupling of active, self-motile particles to topological constraints can give ris

237 ly increases the accumulation and capture of motile pathogens (E. coli) within the microtrap structur

238 tic attraction, trapping, and destruction of motile pathogens.

239 n the fluid dynamic niches of motile and non-motile phytoplankton, and highlights that rapid response

240 deleterious effects of strong turbulence on motile phytoplankton, these results point to an active a

241 Bacteria switch only intermittently to motile planktonic lifestyles under favorable conditions.

242 up within the Amoebozoa well known for their motile plasmodia and morphologically complex fruiting bo

243 For example, motile, point-like topological defects capture the salie

244 Our data suggest that in motile, polarized cells, RhoA-ROCK interactions prevail

245 Non-motile primary cilia are dynamic cellular sensory struct

246 karyotic cell types and can be motile or non-motile primary cilia.

247 The non-motile primary cilium is a critical sensory organelle on

248 asma membrane (PM) blebbing in this cellular motile process.

249 Microglia preferentially target their motile processes to interact with mushroom spines on abG

250 trating mesenchymal glioblastoma from poorly motile proneural and classical glioblastoma.

251 peptides which have distinct biochemical and motile properties as engineered homodimers.

252 One implication is that regulation of Eg5 motile properties by regulatory proteins or small molecu

253 tors-BicD2, Hook3 and Ninl-all show enhanced motile properties in the presence of LIS1.

254 e demonstrate that upon hitting a host cell, motile Pseudomonas aeruginosa induce a specific gene exp

255 ty in vitro and is localized within distinct motile puncta in L. japonicus root hairs and in Nicotian

256 sts and A549 epithelial cells to probe their motile response to the substrates.

257 l cellular functions in eukaryotes, from the motile responses of unicellular protists, such as Parame

258 The motile rings arise from spontaneous segregation of a hom

259 organize into two adjacent, centimeter-scale motile rings surrounding the entire colony.

260 jor signaling systems-quorum sensing and the motile-sessile switch mediated by cyclic-di-GMP-by two d

261 widespread, governing the transition between motile/sessile and unicellular/multicellular behaviors.

262 ruitment and subsequent ER remodeling to the motile side of steering growth cones.

263 explore the environment whisking with their motile snout vibrissae.

264 use of the succession between motile and non-motile species when conditions turn turbulent.

265 y between growth, mechanical stress from the motile species, and friction provided by the non-motile

266 le species, and friction provided by the non-motile species, fully reproduces the observed flower-lik

267 These are the large, generalist, motile species, such as cod and haddock.

268 ending on the local concentration of the non-motile species.

269 different cell types based on their relative motile speed.

270 reduced fast (A) and slow (B) progressively motile sperm (p < 0.05) after sexing.

271 hology, volume, DNA fragmentation, and total motile sperm count) at 6 months after randomization.

272 ion, motility, morphology, volume, and total motile sperm count) were not significantly different bet

273 We reveal that motile sperm domain-containing protein 2 (MOSPD2), a pro

274 of 86% of all sperm and 82% of progressively motile sperm from the original sample while removing whi

275 Differentially methylated (DM) loci in motile sperm were identified using reduced representatio

276 is exposed on the head region of viable and motile sperm, with PtdSer exposure progressively increas

277 of 33% of all sperm and 41% of progressively motile sperm.

278 ated with the concentration of progressively motile sperm.

279 Borrelia burgdorferi is a highly motile spirochete due to its periplasmic flagella.

280 Growth cones are complex, motile structures at the tip of an outgrowing neurite.

281 The exertion of external control over the motile structures powered by biomolecular motors has rem

282 ad based mechanism ensures that cells in the motile subpopulation have a tenfold enhanced likelihood

283 Motile subpopulations in microbial communities are belie

284 A conserved motile system is critical to their life cycles and drive

285 hydrogel system pioneers the study of active motile systems in porous media and has the potential to

286 d utilization of collective behavior between motile systems powered by biomolecular motors, and we di

287 a mechanical program within otherwise highly motile T cells that sustains the symmetry and stability

288 with cells in the migratory state being more motile than cells in the proliferative state.

289 Although phages are not motile themselves, they can infect motile bacterial host

290 .SIGNIFICANCE STATEMENT Growth cones are the motile tips of growing axons whose guidance behaviors re

291 ar stresses from measured traction forces in motile tissues and show that such traction-based stresse

292 typic cell migration screen using two highly motile TNBC cell lines (Hs578T and MDA-MB-231) to provid

293 ry pathways that control the transition from motile to sessile lifestyle, production of extracellular

294 oscopy demonstrated that LN neutrophils were motile, trafficked into LNs from both blood and tissues

295 These locally confined but highly motile Treg cells limit Th17 cells from accessing APCs a

296 fungi locate and infect their hosts during a motile, unicellular 'zoospore' life stage.

297 the Golgi generates MT network asymmetry in motile vertebrate cells.

298 ll to generate endoplasmic-reticulum-derived motile vesicles containing viral replication complexes.

299 Further, we found that motile Vibrio cells induce expression of the proinflamma

300 Many metal reducing bacteria are motile with their run-and-tumble behavior exhibiting ser