ライフサイエンスコーパス: motor protein

1 that is distinct from any reported for a DNA motor protein.

2 Arabidopsis mitochondrial-localized kinesin motor protein.

3 nt chain-ribosome complex or the SecA ATPase motor protein.

4 ch regulation can be achieved by any mitotic motor protein.

5 e dynactin complex, a cofactor for dynein, a motor protein.

6 utions similar to myosin, the major cellular motor protein.

7 wly discovered conformational state for this motor protein.

8 is assisted in D loop formation by the Rad54 motor protein.

9 vered a novel spindle-associated microtubule motor protein.

10 itude higher than the speed of an individual motor protein.

11 nodevices operating with surface-immobilized motor proteins.

12 ntation are spatially separated by molecular motor proteins.

13 ein can occur in a manner unimpeded by other motor proteins.

14 had active super-diffusive motions driven by motor proteins.

15 rs that recruit downstream mediators such as motor proteins.

16 ces imposed on the microtubules by molecular motor proteins.

17 ntous actin (F-actin) with myosin-associated motor proteins.

18 d organelles are transported by ensembles of motor proteins.

19 ibility of using molecular sorters driven by motor proteins.

20 hanical work by polymerization processes and motor proteins.

21 ther the CheA chemotaxis kinase or flagellar motor proteins.

22 isms seen in ion channels, transporters, and motor proteins.

23 ath of single budding yeast kinesin-8, Kip3, motor proteins.

24 irected movement on microtubules mediated by motor proteins.

25 rom mechanical socket wrenches to biological motor proteins.

26 ella is driven by forces generated by dynein motor proteins.

27 bules in association with multiple copies of motor proteins.

28 d an unusual structural element in kinesin-5 motor proteins.

29 in cells is facilitated by microtubule-based motor proteins.

30 ing with microtubule dynamics and associated motor proteins.

31 microtubule trackways by kinesin and dynein motor proteins.

32 anelles and vesicles actively transported by motor proteins.

33 c peptide motifs, cytoskeletal elements, and motor proteins.

34 havior of biological molecular machines like motor proteins.

35 ntin function in cell migration to myosin II motor proteins.

36 filament sliding is driven by the action of motor proteins.

37 More than half coded for mitochondrial motor proteins.

38 ile activity of nonmuscle myosin IIA (NMIIA) motor proteins.

39 assemble a bipolar spindle in the absence of motor proteins.

40 n receptors communicate with the proteasomal motor proteins.

41 zipcodes that interact with RNA binding and motor proteins.

42 New work shows that two kinesin-4 motor proteins act to shorten the domain of overlapping

43 The ability to coordinate the timing of motor protein activation lies at the center of a wide ra

44 Axonal transport is the process whereby motor proteins actively navigate microtubules to deliver

45 tinct parameters, environmental rigidity and motor protein activities, we observe that the stiffness-

46 Tight modulation of motor protein activity is necessary, but little is known

47 filament polymerization, cross-linking, and motor-protein activity.

48 her, we show that Miro couples MICOS to TRAK motor protein adaptors to ensure the concerted transport

49 MglA directly interacts with the motor protein AglR, and the spatial distribution of AglR

50 The movement of a molecular motor protein along a cytoskeletal track requires commun

51 smic dynein is the most complex cytoskeletal motor protein and is responsible for numerous biological

52 Here, we have used the bacterial SecA ATPase motor protein and SecYEG channel complex to address this

53 essivity has not been observed for any other motor protein and suggests that kinesin-3 motors are evo

54 ics of mitochondria are regulated by several motor proteins and a microtubule network.

55 mechanotransduction mechanism is mediated by motor proteins and by the enhancement of microtubule-, a

56 anosensitive biological nanomachines such as motor proteins and ion channels regulate diverse cellula

57 utilize in vitro reconstitution of purified motor proteins and non-enzymatic microtubule-associated

58 t transient attachments of plus-end-directed motor proteins and nonmotile cross-linker proteins are n

59 tions between active forces from an array of motor proteins and passive mechanical resistance from th

60 f fluorescently labeled, processive, dimeric motor proteins and propose a unified algorithm to correc

61 n and Dynein, but interactions between these motor proteins and their mechanisms of action are unclea

62 ospring to human myosin VI, a mechanosensory motor protein, and demonstrate nanometre-precision singl

63 or a member of the UNC-104/Imac/KIF1A-family motor proteins, and is required for proper localization

64 iding across a surface coated with kinesin-1 motor proteins, and that energetic considerations sugges

65 tion of unconventional functions for kinesin motor proteins, and we propose that Kif13b kinesin acts

66 study of kinesin-1 has shed new light on how motor proteins are able to move along microtubules insid

67 Motor proteins are active enzymatic molecules that suppo

68 Motor proteins are biological machines that convert chem

69 Although motor proteins are essential cellular components that ca

70 Cytoskeletal motor proteins are essential to the function of a wide r

71 ral attribute of life, and chemically driven motor proteins are nature's choice to accomplish it.

72 Motor proteins are nature's solution for directing movem

73 , forces generated at the molecular level by motor proteins are transmitted by disordered fiber netwo

74 While interactions with and functions for MT motor proteins are well characterized and extensively re

75 les, which we correlate with the activity of motor proteins, as predicted by existing theories of act

76 During mitosis, motor proteins associate with microtubules to exert push

77 Motor protein-based active transport is essential for mR

78 ule containing the mRNAs for axonemal dynein motor proteins becomes highly polarized to the distal en

79 However, the physical basis for how motor proteins behave in these highly crowded environmen

80 Kinesin-5 is a slow homotetrameric motor protein best known for its essential role in the m

81 oteins, glycolytic enzymes, and cytoskeleton/motor proteins, but the core germ plasm proteins Vas, Tu

82 A motor protein called Klp10A ensures that germline stem c

83 ong with numerical simulations, reveal how a motor protein can function as an analog converter, "read

84 Our study reveals how motor proteins can mold liquid crystalline droplets and

85 ensembles of kinesin-5, a conserved mitotic motor protein, can push apart overlapping antiparallel m

86 re is generated by two bipolar arrays of the motor protein cardiac myosin II extending from the thick

87 ucing expression of the kinesin-like mitotic motor protein CENP-E.

88 Kinesin-1 is a dimeric motor protein, central to intracellular transport, that

89 ssive movement as a heterodimer with the non-motor proteins Cik1 or Vik1.

90 s-linking proteins, and enzymatically active motor proteins collectively self-organize into various p

91 RecBCD always overwhelms FtsK when these two motor proteins collide while traveling along the same DN

92 Cytoplasmic dynein is a eukaryotic motor protein complex that, along with its regulatory pr

93 function provided by pRNA is carried on the motor protein components in other phages.

94 Myosin motor proteins convert chemical energy into force and mo

95 The reliability by which molecular motor proteins convert undirected energy input into dire

96 rone, the imitation switch (ISWI) ATP-driven motor protein, core histones, template DNA, and ATP.

97 exert forces to slide filaments, whereas non-motor proteins crosslink filaments into higher-order mot

98 capsid protein, hexon, directly recruits the motor protein cytoplasmic dynein following virion entry.

99 capsid protein hexon recruits the molecular motor protein cytoplasmic dynein in a pH-dependent manne

100 r et al provide compelling evidence that the motor protein cytoplasmic dynein provides the necessary

101 and spindle positioning, are mediated by the motor protein cytoplasmic dynein, which produces force o

102 The presence of a microtubule-crosslinking motor protein decreased the number of accessible types o

103 Kinesin-8 motor proteins destabilize microtubules.

104 Perturbations of microtubules and motor proteins disrupt this sequence of events.

105 These motor proteins drive motility by using energy derived fr

106 The kinesin-14 motor proteins (Drosophila melanogaster Ncd, Saccharomyc

107 The motor protein dynein drives autophagosome motility from

108 nal change in the coiled-coil "stalk" of the motor protein dynein.

109 comparisons between different populations of motor proteins (e.g., with distinct mutations or linked

110 nd that Abeta(1-42) inhibits the microtubule motor protein Eg5/kinesin-5.

111 esin-14a) is best known as a multifunctional motor protein essential for mitosis.

112 with this finding, FOXJ1-regulating axonemal motor protein expression is absent in respiratory cells

113 ularly robust to abundance variations of the motor protein FliM.

114 binds to the N-terminal peptide of the FliM motor protein (FliM(N)).

115 ular photodynamic steps, action of molecular motors, protein folding, diffusion, etc. down to the pic

116 ule imaging, allowing the tracking of single motor proteins for >800 steps with nanometer precision.

117 iro and Milton proteins link mitochondria to motor proteins for axon transport.

118 Va myosins comprise a unique group of myosin motor proteins found in apicomplexan parasites, includin

119 Myosins are a family of actin-based motor proteins found in many organisms and are categoriz

120 teins such as cofilin and contractile myosin motor proteins fragment these nominally stable structure

121 axoneme contains, along most of its length, motor proteins from the axonemal dynein family.

122 Motor proteins from the kinesin-8 family depolymerize mi

123 e, we show that these PS-mediated effects on motor protein function are via a pathway that involves g

124 hat PS and GSK-3beta are required for normal motor protein function.

125 Mitotic motor proteins generate force to establish and maintain

126 dle is proposed to depend on nanometer-sized motor proteins generating forces that scale with a micro

127 resolved structures of the bacteriophage T4 motor protein gp17 suggests that this motor generates la

128 (MT) motility by surface-tethered kinesin-1 motor proteins has been widely studied, as well as appli

129 Two forms of an unconventional myosin motor protein have separate functions in the growth and

130 systems based on cytoskeletal filaments and motor proteins have become promising tools for a wide ra

131 the structures and chemomechanical cycles of motor proteins have been extensively investigated, the s

132 evolutionarily conserved kinesin-5 family of motor proteins have been shown to play an essential role

133 We measured the density of the adsorbed motor protein (heavy meromyosin, HMM) using quartz cryst

134 eins implicated in D loop disruption are DNA motor proteins/helicases that act by moving DNA junction

135 tween murine RNA-binding proteins (RBPs) and motor proteins, here we identified protein interaction w

136 ellar transport (IFT) is mediated by kinesin motor proteins; however, the function of the homodimeric

137 identify the minus end-directed microtubule motor protein HSET as a direct binding partner of CEP215

138 e microtubule dependent, with 19 microtubule motor proteins implicated in at least one nuclear behavi

139 ae Mph1, a member of the FANCM family of DNA motor proteins important for DNA replication fork repair

140 s the primary minus-end-directed microtubule motor protein in animal cells, performing a wide range o

141 stin (SLC26a5) has evolved, now serving as a motor protein in outer hair cells (OHCs) of the mammalia

142 ermine the mechanokinetic properties of this motor protein in situ.

143 ions in DYNC1H1, which encodes a microtubule motor protein in the dynein-dynactin complex and one of

144 volution to cope with the lack of processive motor proteins in bacteria.

145 alled carbon nanotubes targeted to kinesin-1 motor proteins in COS-7 cells.

146 DNA2-like helicase-nucleases and DNA looping motor proteins in general.

147 of nanometer-scale movements of DNA and RNA motor proteins in real time.

148 on to visualize and quantify the movement of motor proteins in real-time and in different depth plane

149 sting a novel role for the opposite-directed motor proteins in regulating migration velocity.

150 TPX2, and HURP [7, 10-12], Ran also controls motor proteins, including Kid and HSET/XCTK2 [13, 14].

151 We find further that, surprisingly, the motor proteins interact with Nesprin-2 through the dynei

152 Nonmuscle myosin II (NM-II) is an important motor protein involved in cell migration.

153 dition, FAM120A associated with kinesins and motor proteins involved in cargo movement along microtub

154 lation of non-muscle Myosin II, but how this motor protein is spatiotemporally controlled is incomple

155 ucidating the mechanisms that regulate these motor proteins is central to understanding genome mainte

156 racellular cargo transport by kinesin family motor proteins is crucial for many cellular processes, p

157 curately measure mechanochemical coupling in motor proteins is ensemble averaging of individual traje

158 g axons, a physiological process mediated by motor proteins, is essential for neuronal function and s

159 s from one anchor site to another, mimicking motor proteins, is realized through a toehold-mediated D

160 Together with the motor protein KIF13B, ADAP1 is also thought to mediate d

161 The mitotic kinesin motor protein KIF14 is essential for cytokinesis during

162 a yeast two-hybrid screen, we identified the motor protein Kif15 as a potential interacting partner o

163 aNrxns, but both depended on the microtubule motor protein KIF1A and neuronal activity regulated the

164 terozygous missense mutations in the kinesin motor protein KIF21A or in the beta-tubulin isotypes TUB

165 Instead, the microtubule depolymerizing motor protein kif2a functions to modulate spindle size.

166 Here we identified the key cellular motor protein KIF3A as a cellular substrate phosphorylat

167 We identified the type II kinesin motor protein KIF3A as a critical kinesin factor in the

168 Here we show that genetic deletion of the motor protein Kif3a in dental mesenchyme results in an a

169 s, the microtubule crosslinker PRC1, and the motor protein KIF4A.

170 sported to overlap zones, which required two motor proteins, Kif4A and a Kif20A paralog.

171 or overexpression depends on the microtubule motor protein kinesin 1 (KIF5).

172 oaches by focusing on its application to the motor protein kinesin, which undergoes several conformat

173 een identifies KIF5B, the heavy chain of the motor protein kinesin-1, as a new PA-binding protein.

174 hat interacts with both microtubules and the motor protein kinesin-1, plays a key role at branch junc

175 -dependent manner, driven by the microtubule motor protein kinesin-1.

176 The motor proteins kinesin and dynein transport organelles,

177 After briefly introducing the motor proteins kinesin and myosin and their associated c

178 s nidulans reveal a complex interplay of the motor proteins kinesin-3 and dynein, which co-operate to

179 The old SPB recruits the kinesin motor protein Kip2, which then translocates to the plus-

180 Intraflagellar transport (IFT) motor protein localization, but not velocities, in AWA c

181 an kinesin-like protein KIF14, a microtubule motor protein, localizes at the midbody to finalize cyto

182 the well-known active transport of cargo by motor proteins, many MT-binding proteins seem to adopt d

183 The kinesin-13 motor protein MCAK is a potent microtubule depolymerase.

184 as a model for understanding fundamentals of motor protein mechanochemistry and for interpreting func

185 Regulation of microtubule dynamics, motor proteins, microtubule crosslinking, and chromatid

186 nvestigated whether prestin, an OHC-specific motor protein, might be involved.

187 ises from the coordinated activity of dynein motor protein molecules arrayed along microtubule double

188 has revealed that in the bacterial flagellar motor, protein molecules in both the rotor and stator ex

189 ntribute to cytoskeleton-based regulation of motor protein motility, we extracted intact microtubule

190 onents of the transport machinery, including motor proteins, motor adaptors and microtubules, have be

191 ers serve as one-dimensional tracks on which motor proteins move to perform their biological roles.

192 rack, e.g., a cytosolic cargo transported by motor proteins moving along a microtubule.

193 In physiological settings, all nucleic acids motor proteins must travel along substrates that are cro

194 tion to stereocilia tips is dependent on the motor protein MYO15A and its cargo EPS8.

195 ation to the stereocilia tips depends on the motor protein MYO15A and its cargo EPS8.

196 The motor protein myosin drives muscle and nonmuscle motilit

197 We also show that Rab11 and the associated motor protein Myosin V play essential roles in both endo

198 Here we show that the unconventional motor protein myosin Va (MyoVa) is an effector of Rab8A

199 Mutations in the motor protein Myosin Vb (Myo5B) or the soluble NSF attac

200 tween CLCa and the long isoform of the actin motor protein myosin VI, which is expressed exclusively

201 Mutations in the MYO7A gene, encoding the motor protein myosin VIIa, can cause Usher 1B, a deafnes

202 Various forms of the actin-specific motor protein myosin XI exist in plant cells and might b

203 adhesion complex based on cadherins and the motor protein myosin-7b (MYO7B) links the tips of intest

204 as a model, we recently discovered that the motor protein myosin-Va works with dynamic actin tracks

205 emonstrate a role for the filopodia-inducing motor protein Myosin-X (Myo10) in mutant p53-driven canc

206 the molecular switch Rab8A connects with the motor protein MyoVa to mobilize GLUT4 vesicles toward th

207 w PARs regulate the behavior of the cortical motor protein nonmuscle myosin (NMY-2) to complement rec

208 Prestin is the motor protein of cochlear outer hair cells.

209 used to generate inhibitable versions of any motor protein of interest.

210 Motor proteins of the conserved kinesin-14 family have i

211 irectional step distribution of yeast dynein motor protein on the MT surface by combing intrinsic fea

212 the motility of single fluorescently labeled motor proteins on these cytoskeletons.

213 that target microtubule integrity the dynein motor protein, or inhibit mitochondrial ROS production s

214 mains unclear how cytoskeletal filaments and motor proteins organize into cellular scale structures a

215 Motor protein phenomena have inspired theoretical models

216 Kinesin microtubule motor proteins play essential roles in division, includi

217 Members of the conserved FANCM family of DNA motor proteins play key roles in genome maintenance proc

218 SecA ATPase motor protein plays a central role in bacterial protein

219 (HSET), a member of the kinesin-14 family of motor proteins, plays an essential role in centrosomal b

220 Cochlear outer hair cells (OHC) express the motor protein, prestin, which is required for sensitivit

221 The nonmuscle myosin II motor protein produces forces that are essential to driv

222 During mitosis, Kif11, a kinesin motor protein, promotes bipolar spindle formation and ch

223 function in eucaryotic cells, facilitated by motor proteins-proteins converting chemical energy into

224 re generated by non-muscle myosin II (MyoII) motor proteins pulling filamentous actin (F-actin).

225 ally and functionally interacts with the DNA motor protein RAD54.

226 a method, named reversible association with motor proteins (RAMP), for manipulation of organelle pos

227 picture of transport by direct attachment to motor proteins, recent evidence shows that a number of i

228 , microtubule-associated proteins (MAPs) and motor proteins regulate microtubule growth, shrinkage, a

229 crotubule assembly-disassembly, the roles of motor proteins remain unexplored.

230 l cells, yet how mRNA granules interact with motor proteins remains poorly understood.

231 icles within cells, mediating recruitment of motor proteins required for microtubule-based traffickin

232 mic dynein is a homodimeric microtubule (MT) motor protein responsible for most MT minus-end-directed

233 reducing the level of either of two Kinesin motor proteins responsible for anterograde vesicle trans

234 Dyneins are motor proteins responsible for transport in the cytoplas

235 As with many ring-shaped motor proteins, Rho activity is modulated by a variety o

236 nding Rubisco inhibitors are released by the motor protein Rubisco activase (Rca).

237 e Sec-channel - SecYEG - associates with the motor protein SecA to mediate the ATP-dependent transpor

238 n comes from ATP hydrolysis by the cytosolic motor-protein SecA, in concert with the proton motive fo

239 h disrupts the back-to-front gradient of the motor protein, slowing down locomotion but promoting ant

240 CD4(+) T cells in DCs, including the dynein motor protein Snapin.

241 into canonical nucleosomes by an ATP-driven motor protein such as ACF or Chd1.

242 be converted into canonical nucleosomes by a motor protein such as ACF.

243 ore the mechanochemical cycles of processive motor proteins such as kinesin-1, but it has proven diff

244 s and ribosomes) to intracellular transport (motor proteins such as kinesins or dyneins).

245 In many cases, the activity of motor proteins such as nonmuscle myosins is required for

246 selectively attaching different microtubule motor proteins (such as kinesin and dynein) to the corre

247 echniques for measuring the motion of single motor proteins, such as FRET and optical tweezers, are l

248 sport in a nerve cell, where small groups of motor proteins, such as kinesins and cytoplasmic dynein,

249 ized proteins: actin, tubulin, and driven by motor proteins, such as myosin, kinesin, and dynein.

250 Kinesin is part of the microtubule-binding motor protein superfamily, which serves important roles

251 Such complexity is present in myosin motor protein systems, and computational modeling is ess

252 ocytosis occurred when blocking myosin II, a motor protein that can be phosphorylated upon MLCK activ

253 associated with diverse cellular activities motor protein that enables cells to survive extreme stre

254 Myosin II is the motor protein that enables muscle cells to contract and

255 hedral prohead shell is catalyzed by TerL, a motor protein that has ATPase, endonuclease, and translo

256 Myosin is a motor protein that is essential for a variety of process

257 Cytoplasmic dynein is a dimeric AAA(+) motor protein that performs critical roles in eukaryotic

258 Cytoplasmic dynein is a motor protein that walks along microtubules (MTs) and pe

259 explicitly incorporates force generation by motor proteins that can act normally or tangentially to

260 DNA helicases are motor proteins that couple the chemical energy of nucleo

261 purified microtubules and light-activatable motor proteins that crosslink and organize the microtubu

262 3s are members of the kinesin superfamily of motor proteins that depolymerize microtubules (MTs) and

263 The human genome encodes 45 kinesin motor proteins that drive cell division, cell motility,

264 Kinesin motor proteins that drive intracellular transport share

265 microtubules within the spindle is driven by motor proteins that exert forces to slide filaments, whe

266 Class 1 myosins are monomeric motor proteins that fulfill diverse functions at the mem

267 A small molecule called EMD 57033 can repair motor proteins that have stopped working as a result of

268 bers of the kinesin superfamily of molecular motor proteins that is critical for kinesin's processive

269 the coordinated regulation of the different motor proteins that mediate dendritic vesicle transport

270 and dendrites primarily depends on molecular motor proteins that move along the cytoskeleton.

271 and Rdh54 are closely related ATP-dependent motor proteins that participate in homologous recombinat

272 Kinesin-14s are microtubule-based motor proteins that play important roles in mitotic spin

273 icative helicases are hexameric, ring-shaped motor proteins that translocate on and unwind DNA.

274 gnals that converge on a competition between motor proteins that ultimately control lysosomal movemen

275 DNA helicases are motor proteins that unwind double-stranded DNA (dsDNA) t

276 n and dynein are microtubule (MT)-associated motor proteins that, among other functions, facilitate i

277 Inspired by biological motor proteins, that efficiently convert chemical fuel t

278 ially associate with microtubules and dynein motor protein, thereby resulting in differential taxane

279 ar trafficking by regulating the activity of motor proteins through the organization of the filament

280 n diverse animal taxa by linking microtubule motor proteins to a marker protein on the cell cortex lo

281 We used an optogenetic approach to recruit motor proteins to cargo in real time within axons or den

282 The response of motor proteins to external loads underlies their ability

283 g and biochemical reconstitution with myosin motor proteins to show single piconewton forces applied

284 and provide GTP to dynamins, allowing these motor proteins to work with high thermodynamic efficienc

285 led to a proposed mechanism wherein the gp17 motor protein translocates DNA by transitioning between

286 ble doublet microtubules (DMTs), along which motor proteins transmit force for ciliary motility and i

287 Cytoplasmic dynein, a microtubule-based motor protein, transports many intracellular cargos by m

288 nals by impairing anterograde SV trafficking motor protein Unc104/KIF1A rescues the enhanced-learning

289 th microtubules or coprecipitate with dynein motor protein, unlike ARv567.

290 e motility of microtubules driven by kinesin motor proteins using various photoprotection strategies,

291 ycled by binding to non-muscle myosin IIA, a motor protein, via the cytoplasmic tail (CT).

292 by active energy-consuming processes such as motor protein walking and actin polymerization.

293 Through the addition of enzymatically active motor proteins, we construct composite assemblies, evoca

294 dual cilia that correctly expressed axonemal motor proteins were motile and did not exhibit obvious b

295 ound that BB0286 (FlbB) is a novel flagellar motor protein, which is located around the flagellar bas

296 are controlled by nonmuscle myosin II (NMII) motor proteins, which are tightly regulated via the phos

297 However, little is known about how motor proteins, which follow individual microtubule prot

298 he HARP2, and other domains found in certain motor proteins, which may explain why only a subset of D

299 Kip3 is a multifunctional motor protein with microtubule depolymerase, plus-end mo

300 It is understood that motor proteins work in teams enabling unidirectional and