ライフサイエンスコーパス: multidrug resistance-associated protein

1 ug efflux pump similar to P-glycoprotein and multidrug resistance-associated protein.

2 tivity has recently been associated with the multidrug resistance-associated protein.

3 P-glycoprotein multidrug-resistance gene or multidrug resistance-associated protein.

4 on transporting polypeptides and basolateral multidrug resistance associated proteins.

5 ther Notch1 is involved in the expression of multidrug resistance-associated protein 1 (ABCC1/MRP1; h

6 Multidrug resistance-associated protein 1 (adenosine tri

7 Overexpression of plasma membrane multidrug resistance-associated protein 1 (MRP-1) in Ewi

8 The multidrug resistance-associated protein 1 (MRP1) and the

9 ivered IgGs can inhibit the drug efflux pump multidrug resistance-associated protein 1 (MRP1) and the

10 by estrogen encoded the chick homolog of the multidrug resistance-associated protein 1 (MRP1) gene.

11 The multidrug resistance-associated protein 1 (MRP1) has bee

12 Multidrug resistance-associated protein 1 (MRP1) is a dr

13 Multidrug resistance-associated protein 1 (MRP1) is a me

14 Multidrug resistance-associated protein 1 (MRP1) is an A

15 cytometry and immunostaining have shown that multidrug resistance-associated protein 1 (MRP1) is prev

16 regulates the cell surface expression of the multidrug resistance-associated protein 1 (MRP1) transpo

17 BD1 and the Tyr1302 residue in NBD2 of human multidrug resistance-associated protein 1 (MRP1) was mut

18 g cassette (ABC) transporters, such as P-gp, multidrug resistance-associated protein 1 (MRP1), and br

19 on a known ATP-binding cassette transporter, multidrug resistance-associated protein 1 (MRP1), and fo

20 drug efflux pumps, P-glycoprotein (Pgp) and multidrug resistance-associated protein 1 (MRP1), correl

21 resistance gene-1 P-glycoprotein (MDR1) and multidrug resistance-associated protein 1 (MRP1), has be

22 hat the function of Ycf1p, yeast ortholog of multidrug resistance-associated protein 1 (MRP1), is reg

23 GSH) and that the GSH-conjugate transporter, multidrug resistance-associated protein 1 (MRP1), mediat

24 across erythrocyte membranes is inhibited by multidrug resistance-associated protein 1 (MRP1)-specifi

25 es the leukotriene C(4) (LTC(4)) transporter multidrug resistance-associated protein 1 (MRP1).

26 cluding permeability glycoprotein (P-gp) and multidrug resistance-associated protein 1 (MRP1).

27 P-Glycoprotein (P-gp, ABCB1), multidrug resistance-associated protein 1 (MRP1, ABCC1),

28 th respect to potency and selectivity toward multidrug resistance-associated protein 1 (MRP1, ABCC1).

29 Multidrug resistance-associated protein 1 (Mrp1; Abcc1)

30 ctions of flavonoids with P-glycoprotein and multidrug resistance-associated protein 1 have been repo

31 onferring multidrug resistance such as MRP1 (multidrug resistance-associated protein 1) and LRP (lung

32 ved in drug resistance, namely GST and MRP1 (multidrug resistance-associated protein 1), are critical

33 emia, with permeability glycoprotein (P-gp), multidrug resistance-associated protein 1, and breast ca

34 es expressing high levels of P-glycoprotein, multidrug resistance-associated protein 1, or ABCG2, PhA

35 hree major drug transporters P-glycoprotien, multidrug resistance-associated protein 1, or ATP-bindin

36 sette C 1 (ABCC1) transporter, also known as multidrug resistance-associated protein 1.

37 there is upregulation of P-glycoprotein and multidrug resistance-associated proteins 1 and 2.

38 ate a facile induction of mRNAs for mRFC and multidrug resistance-associated proteins 1 and 3 in inte

39 Multidrug resistance-associated proteins 1 and 3 were, l

40 erase P1 (3.74-fold, 1.3-33.1, p<0.0001) and multidrug resistance associated protein-1 (4.06-fold, 1.

41 ne S-transferase P1 and the drug transporter multidrug resistance associated protein-1.

42 Multidrug resistance-associated protein-1 (MRP-1), an ac

43 dramatic UL138-mediated loss of cell surface multidrug resistance-associated protein-1 (MRP1) and the

44 ts ATP binding cassette subfamily C member 2/multidrug resistance associated protein 2 (ABCC2/MRP2),

45 Multidrug resistance associated protein 2 (Mrp2) is a ca

46 s of the canalicular organic ion transporter multidrug resistance associated protein 2 (Mrp2) on chlo

47 suppressed the ability of CAR to induce the multidrug resistance associated protein 2 (MRP2), a bili

48 sporters, bile salt export pump (Abcb11) and multidrug resistance-associated protein 2 (Abcc2).

49 Canalicular multidrug resistance-associated protein 2 (Mrp2) and bas

50 ane cholesterol on the transport kinetics of multidrug resistance-associated protein 2 (MRP2) and of

51 ic retrieval and function of the canalicular multidrug resistance-associated protein 2 (Mrp2) and the

52 breast cancer resistance protein (BCRP), and multidrug resistance-associated protein 2 (MRP2) at the

53 holate cotransporting polypeptide (NTCP) and multidrug resistance-associated protein 2 (MRP2) by conv

54 eval of the bile salt export pump (Bsep) and multidrug resistance-associated protein 2 (Mrp2) from th

55 The role of multidrug resistance-associated protein 2 (Mrp2) in the

56 Multidrug resistance-associated protein 2 (MRP2) is an A

57 n of the ATP-dependent conjugate export pump multidrug resistance-associated protein 2 (Mrp2) is dimi

58 Under ischemic stress, multidrug resistance-associated protein 2 (MRP2) translo

59 Previous studies suggest that the multidrug resistance-associated protein 2 (Mrp2) transpo

60 ) as a positive regulator of P-glycoprotein, multidrug resistance-associated protein 2 (Mrp2), and br

61 1A1 (Oatp1a1), the hepatobiliary transporter multidrug resistance-associated protein 2 (Mrp2), and th

62 pical efflux ATP-binding protein transporter multidrug resistance-associated protein 2 (MRP2).

63 Multidrug resistance-associated protein 2 (Mrp2, Abcc2)

64 The multidrug resistance-associated protein 2 (MRP2, ABCC2),

65 Multidrug resistance-associated protein 2 (Mrp2, Abcc2),

66 Multidrug resistance-associated protein 2 (MRP2/ABCC2) i

67 The multidrug resistance-associated protein 2 (MRP2/ABCC2) p

68 Multidrug resistance-associated protein 2 (Mrp2/Abcc2),

69 0 administration significantly induced renal multidrug resistance-associated protein 2 and 4, peroxis

70 In contrast, the multidrug resistance-associated protein 2 expression in

71 f 3 xenobiotic efflux pumps, P-glycoprotein, multidrug resistance-associated protein 2, and breast ca

72 d that androgen glucuronides are effluxed by multidrug resistance-associated proteins 2 and 3.

73 tes, has been reported to selectively tether multidrug-resistance-associated protein 2 to the apical

74 luorescence showed that apical transporters (multidrug-resistance-associated protein 2, bile salt exp

75 rting polypeptides 1 and 2 (Oatp1 and 2) and multidrug resistance associated protein-2 (Mrp2) in preg

76 b, the bile salt export pump (Bsep), and the multidrug resistance-associated protein-2 (Mrp2) in medi

77 ycoprotein, ATP binding cassette b1 (Abcb1); multidrug resistance-associated protein-2 (Mrp2), Abcc2;

78 nofluorescence analyses confirmed that MRP3 (multidrug resistance associated protein 3), which was hi

79 ic basolateral membrane export transporters, multidrug resistance-associated protein 3 (Mrp3) and Mrp

80 ction of the cytochrome p450 CYP3A11 and the multidrug resistance-associated protein 3 transporter, w

81 blood-brain barrier, P-glycoprotein (ABCB1), multidrug resistance associated protein 4 (ABCC4) and br

82 polypeptide (NTCP) expression and activity, multidrug resistance-associated protein 4 (MRP4) overexp

83 malignant lesions, we aim to investigate the multidrug resistance-associated protein 4 (MRP4)-depende

84 CK19 also positively regulated multidrug resistance-associated protein 4 expression at

85 cassette (ABC) family, P-glycoprotein (Pgp), multidrug-resistance associated protein 4 (MRP4) and bre

86 Multidrug, resistance-associated protein-4 (MRP4) is a m

87 ABCC6 encodes multidrug resistance-associated protein 6 (MRP6), which

88 te-binding cassette family of genes, encodes multidrug resistance-associated protein 6, a putative tr

89 g on the transcriptional regulation of MRP7 (multidrug resistance associated protein 7) gene expressi

90 By contrast, the expression of the multidrug resistance-associated protein and the P-glycop

91 e transporters such as P-glycoprotein (Pgp), multidrug resistance-associated protein, and breast canc

92 Furthermore, and in contrast to the multidrug resistance-associated proteins, BCRP also tran

93 Verapamil and cyclosporin A, blockers of the multidrug resistance-associated protein, decreased UVA-i

94 Inhibitors of TDF's apical multidrug-resistance-associated protein efflux-transport

95 nd expression of Mrp3, another member of the multidrug resistance-associated protein family, in norma

96 g for glutathione S-transferase Pi (GST-Pi), multidrug resistance-associated protein genes (MRP1/MRP2

97 hout overexpression of P-glycoprotein or the multidrug-resistance associated protein have raised the

98 ium taurocholate cotransporting polypeptide, multidrug resistance-associated protein (Mdr) 2, and bil

99 (99m)Tc-mebrofenin, and efflux transporters (multidrug resistance-associated proteins) mediating its

100 Similarly, overexpression of the multidrug resistance-associated protein MRP by HL-60 cel

101 istance is accompanied by mislocalization of multidrug resistance associated protein (MRP) 1 and othe

102 fflux transporter genes with homology to the multidrug resistance associated protein (mrp) and permea

103 P2, were highly homologous to members of the multidrug resistance associated protein (MRP) subfamily.

104 ent studies implicate a role for some of the multidrug resistance associated proteins (MRP), includin

105 One major group of transporters is known as multidrug resistance associated proteins (MRP; ABCC gene

106 breast cancer resistance protein (Bcrp), and multidrug resistance-associated protein (Mrp) 4 in isola

107 Multidrug resistance-associated protein (MRP) actively t

108 Multidrug resistance-associated protein (MRP) and canali

109 We have recently shown that multidrug resistance-associated protein (MRP) and gamma-

110 P-glycoprotein (P-gp) and multidrug resistance-associated protein (MRP) are member

111 ma led us to investigate a possible role for multidrug resistance-associated protein (MRP) as a cause

112 w that maize lpa1 mutants are defective in a multidrug resistance-associated protein (MRP) ATP-bindin

113 at export of glutathione-LDE-adducts through multidrug resistance-associated protein (MRP) channels i

114 Transfection of fibroblasts with the multidrug resistance-associated protein (MRP) did not al

115 n transporting polypeptide (OATP, SLC21) and multidrug resistance-associated protein (MRP) families.

116 dentified cDNA that has been assigned to the multidrug resistance-associated protein (MRP) family of

117 nding cassette transporters belonging to the multidrug resistance-associated protein (MRP) family.

118 The ABCC6 gene encodes MRP6, a member of the multidrug resistance-associated protein (MRP) family.

119 Overexpression of the multidrug resistance-associated protein (MRP) gene has b

120 otection assay, we provide evidence that the multidrug resistance-associated protein (MRP) gene, whic

121 The P. ramorum genome contains 22 multidrug resistance-associated protein (MRP) genes and

122 The multidrug resistance-associated protein (MRP) has been s

123 is associated with the overexpression of (a) multidrug resistance-associated protein (MRP) responsibl

124 cf1p is the prototypical member of the yeast multidrug resistance-associated protein (MRP) subfamily

125 inary experiments indicating that some plant multidrug resistance-associated protein (MRP) subfamily

126 vesicles prepared from cells expressing the multidrug resistance-associated protein (MRP) transport

127 resulted in elevated expression of mRNA for multidrug resistance-associated protein (MRP) within the

128 We have identified a multidrug resistance-associated protein (MRP), ZmMrp3, t

129 ), effectively inhibits growth and regresses multidrug resistance-associated protein (MRP)-overexpres

130 mil did not, indicating the involvement of a multidrug resistance-associated protein (Mrp).

131 rug resistance) P glycoprotein (Pgp) and the multidrug resistance-associated protein (MRP).

132 DR) mediated by P-glycoprotein (P-gp) or the multidrug resistance-associated protein (MRP).

133 Multidrug resistance-associated protein (MRP)1 and canal

134 n this study, we examined the involvement of multidrug resistance-associated protein (MRP)4 (ABCC4) i

135 itro lacking P-gp expression or expressing a multidrug resistance-associated protein (MRP-1).

136 curonosyl-transferase (Ugt) 1a6 and 2b5, and multidrug resistance-associated proteins (Mrp) 2 and 3 m

137 Vinorelbine was transported by human multidrug-resistance associated protein (MRP) 2, and Mrp

138 tant cell lines expressing P-glycoprotein or multidrug-resistance associated protein (MRP).

139 , multidrug-resistance protein 1 (MDR1), and multidrug-resistance-associated protein (MRP) 2 and 3 el

140 sistance mediated by P-glycoprotein (Pgp) or multidrug-resistance-associated protein (MRP) remains a

141 transporters (bile salt export pump [BSEP], multidrug resistance-associated protein [MRP] 2) were un

142 other drug resistance proteins, notably the multidrug resistance-associated protein, MRP, and the lu

143 th MDR, including P-glycoprotein (P-gp), the multidrug resistance associated protein (MRP1), the lung

144 lastoma (NB), the level of expression of the multidrug resistance-associated protein (MRP1) gene is s

145 Multidrug resistance-associated protein (MRP1) transport

146 Multidrug resistance-associated protein (MRP1) transport

147 estigated a high-throughput assay to measure multidrug resistance-associated protein (MRP1)-mediated

148 ith extensive sequence homology to the human multidrug resistance-associated protein (MRP1).

149 In 1992, the multidrug resistance-associated protein (MRP1, ABCC1) wa

150 variety of cells stably expressing MDR1 Pgp, multidrug resistance-associated proteins (MRP1-MRP6), or

151 n of the human ATP-binding cassette protein, multidrug resistance-associated protein, MRP7.

152 CPE cells whereas MK-571, a pan-inhibitor of multidrug resistance associated proteins (MRPs), abolish

153 Multidrug resistance-associated proteins (Mrps) are aden

154 njugate transport, and possible mediation by multidrug resistance-associated proteins (MRPs) have bee

155 Additional drug transporters, such as the multidrug resistance-associated proteins (MRPs), have al

156 ently effluxed into the blood by basolateral multidrug resistance-associated proteins (MRPs).

157 is, and the present study indicates that the multidrug resistance-associated proteins (MRPs/ABCC) are

158 as well as substrates of the plasma membrane multidrug resistance-associated proteins on the uptake o

159 Here we disrupted a gene encoding a putative multidrug resistance-associated protein (PfMRP) that was

160 o AP2 transcription factors and the P. vivax multidrug resistance-associated protein (PvMRP1), an ABC

161 an increase in the activity of pre-existing multidrug resistance-associated protein transporter carr