ライフサイエンスコーパス: multinucleated

1 , whereas 8.7 +/- 1.0% of control cells were multinucleated, 62.4 +/- 8.8% of the NMHC II-B RNAi-trea

2 .8% of the NMHC II-B RNAi-treated cells were multinucleated 72 h after transfection.

3 Physarum polycephalum is a large multinucleated amoeboid cell that extends and develops p

4 In both AIA and CIA, multinucleated and cathepsin K-positive osteoclasts firs

5 Skeletal muscle contains long multinucleated and contractile structures known as muscl

6 duction of distal fine processes, and become multinucleated and hypertrophic.

7 tic constructs exhibit aligned architecture, multinucleated and striated myofibers, and a Pax7(+) cel

8 macrophages/monocytes based on the number of multinucleated and tartrate-resistant alkaline phosphata

9 All osteoclasts (cathepsin K-positive, multinucleated, attached to bone) and osteoclast precurs

10 ssed at these sites, where they fuse to form multinucleated bone-resorbing cells.

11 were enlarged, poikilocytic, and frequently multinucleated, but were able to sustain life despite ex

12 s syncytins forms the syncytiotrophoblast, a multinucleated cell structure essential for fetal develo

13 ly fusion active and led to the formation of multinucleated cell syncytia when expressed in the absen

14 rporates as many as 200 cells into one large multinucleated cell.

15 division without cytokinesis, resulting in a multinucleated cell.

16 als, mandibles and tibiae were isolated, and multinucleated cells (MNCs) were measured.

17 The formation of multinucleated cells (syncytia) is a hallmark of henipav

18 rus-induced cell fusion and the formation of multinucleated cells (syncytia).

19 eficient, OCRL prevented the accumulation of multinucleated cells after acute knockdown of OCRL but c

20 exhibited an increase in both the number of multinucleated cells and cells with swollen flagellar po

21 this study revealed the presence of abnormal multinucleated cells and increased apoptotic cells withi

22 Its failure leads to multinucleated cells and is a possible cause of tumorige

23 tartrate-resistant acid phosphatase-positive multinucleated cells and measuring the expression of ost

24 nhibition of Aurora B by hesperadin produced multinucleated cells and reduced H3S10 phosphorylation.

25 Multinucleated cells are found in diverse contexts and i

26 lonogenic outgrowth, and high percentages of multinucleated cells are found in vivo in remnants of PA

27 Multinucleated cells are important in many organisms, bu

28 Multinucleated cells are relatively resistant to classic

29 lure in mitotic exit, with the appearance of multinucleated cells as a consequence.

30 tartrate-resistant acid phosphatase-positive multinucleated cells at sites of bone erosion.

31 confirmed by immunofluorescence staining on multinucleated cells at the bone surface of inflamed mou

32 indle-shaped cells, as well as flat adherent multinucleated cells capable of spontaneous contractions

33 ure of HPCs manifested by an accumulation of multinucleated cells caused by failed abscission of the

34 Giant multinucleated cells containing nuclei attached by const

35 PARP-inhibitor-induced multinucleated cells fail clonogenic outgrowth, and high

36 eventual degeneration with the formation of multinucleated cells following Cx43 overexpression due t

37 with occasional pseudonuclear inclusion and multinucleated cells in a partly myxoid matrix.

38 tartrate-resistant acid phosphatase-positive multinucleated cells in both cell types.

39 The formation of fused multinucleated cells in ganglia might be associated with

40 nesis was assessed by counting TRAP-positive multinucleated cells in PB CD14+ monocytes cultured with

41 Skeletal muscle consists of multinucleated cells in which the myonuclei are evenly s

42 osophila larval skeletal muscles are single, multinucleated cells of different sizes that undergo tre

43 Osteoclasts are multinucleated cells of the monocyte/macrophage lineage

44 tartrate-resistant acid phosphatase-positive multinucleated cells or resorption pits were observed in

45 ing the transport of nuclear proteins within multinucleated cells remain poorly defined.

46 Other subcellular effects observed included multinucleated cells seen after RNAi to either pgant2 or

47 are not optimized for capturing very large, multinucleated cells such as myotubes.

48 Some multinucleated cells such as those in muscles arise from

49 Myofibers are multinucleated cells that are formed, repaired and maint

50 leost Sternopygus macrurus, electrocytes are multinucleated cells that do not contract yet retain exp

51 cell fusion to form the fully differentiated multinucleated cells that mediate bone resorption.

52 a 40% growth decrease and the appearance of multinucleated cells that result from defective cytokine

53 ty of the population emerges from mitosis as multinucleated cells that subsequently undergo cell deat

54 sis and remarkably, elicits the formation of multinucleated cells that then arrest or die by mitotic

55 ell death was the appearance of enlarged and multinucleated cells that was related to the inhibition

56 Multinucleated cells were characterized as striated musc

57 RANKL immunolabeling and fewer TRAP-positive multinucleated cells were observed in the EA-treated gro

58 matrix are all promoted by myosin-II, and so multinucleated cells with distended membranes--typical o

59 pletion generates supernumerary centrosomes, multinucleated cells, and multipolar spindle formation.

60 g, resulting in cell flattening, senescence, multinucleated cells, decreased S-phase progression, dim

61 dges, micronuclei, centrosome amplification, multinucleated cells, gradual accumulation of DNA damage

62 mitotic phase with the formation of abnormal multinucleated cells, indicating that this compound affe

63 sion led to a highly significant increase of multinucleated cells, nuclear volume, and 3D telomeric a

64 ates that included death, fusion that formed multinucleated cells, or another round of mitosis with n

65 -zoster virus (VZV) characteristically forms multinucleated cells, or syncytia, during the infection

66 Cs to overexpress NS decreases senescent and multinucleated cells, restores morphology, and antagoniz

67 Finally, we find that, in multinucleated cells, scaling is set at the level of sin

68 formation of long intercellular bridges and multinucleated cells, which might explain part of the Co

69 nockdown of I-2 by RNA interference produced multinucleated cells, with supernumerary centrosomes, mu

70 rs abscission and increases the incidence of multinucleated cells.

71 otic errors ensued, producing aneuploid, and multinucleated cells.

72 o undergo proper cytokinesis and resulted in multinucleated cells.

73 nd pleiotropic tendencies largely made up of multinucleated cells.

74 mononuclear preosteoclasts fuse to generate multinucleated cells.

75 n of GEFs in the morphological maturation of multinucleated cells.

76 s, resulting in the accumulation of enlarged multinucleated cells.

77 rounds of endoreduplication and resulting in multinucleated cells.

78 ved cell cycle regulators directs mitosis in multinucleated cells.

79 T in HeLa cells resulted in the formation of multinucleated cells.

80 pensable for psychosine-induced formation of multinucleated cells.

81 and Mat89Bb RNAi in HeLa cells gives rise to multinucleated cells.

82 ng HEK293 cells resulted in the formation of multinucleated cells.

83 f cell membranes are overcome and cells form multinucleated cells.

84 aa3 expression peaked prior to appearance of multinucleated cells.

85 l size, but does this relationship extend to multinucleated cells?

86 Polyploidal giant cancer cells (PGCCs) are multinucleated chemoresistant cancer cells found in hete

87 However, only 32% of these cells were multinucleated compared with 57% in wild-type littermate

88 rated more slowly and about 10% of them were multinucleated compared with fewer than 2% of matched co

89 an enzymatic electrode, due to the use of a multinucleated complex of manganese with mu-oxo units, w

90 ny formation, invasion, and development of a multinucleated dendritic-like phenotype.

91 In multinucleated Dictyostelium discoideum cells, each cent

92 el across the ventral membrane of oversized, multinucleated Dictyostelium discoideum cells.

93 ion of those cells that do divide are either multinucleated, display deformed nuclei, or undergo cell

94 r et al. (2019) examine scaling of nuclei in multinucleated Drosophila muscle fibers and identify glo

95 Syncytiotrophoblast is the multinucleated epithelium of the placenta.

96 a cells, consistent with appearance of large multinucleated erythroblasts in CDA III patients.

97 erythropoiesis characterized by increased bi/multinucleated erythroid precursors in the bone marrow.

98 erodera glycines) induces the formation of a multinucleated feeding site, or syncytium, whose etiolog

99 y endoparasites that induce the formation of multinucleated feeding structures termed syncytia in the

100 bundant in muscles undergoing fusion to form multinucleated fibers and that enforced expression of GR

101 myogenic progenitors were specified to form multinucleated fibers that enabled development of quiesc

102 Each Drosophila larval muscle is a single multinucleated fibre whose morphology reflects expressio

103 We propose that the multinucleated filament creates an environmental niche w

104 Moreover, in multinucleated fission yeast cells, Neumann and Nurse (s

105 acrophages from Xid mice also failed to form multinucleated foreign body giant cells.

106 al demonstrated an intimate association with multinucleated foreign body-type giant cells.

107 ro to certain phthalate plasticizers exhibit multinucleated germ cell (MNG) induction and suppressed

108 ine), maternal hepatotoxicity, and increased multinucleated germ cells (MNGs) in fetal testes without

109 ated implants contained significantly higher multinucleated giant cell (MNGC) density compared to NT,

110 nt did not exhibit signs of cytopathology or multinucleated giant cell (MNGC) formation, which were o

111 ed giant cells (LGCs) are a specific type of multinucleated giant cell containing a characteristic ho

112 ically, I-PGCG was associated with: 1) lower multinucleated giant cell count (P = 0.04); 2) lower den

113 ntercellular signaling mechanisms modulating multinucleated giant cell formation and function are nec

114 targets for the modulation and inhibition of multinucleated giant cell formation and function.

115 g HIV-1 replication, macrophage biology, and multinucleated giant cell formation are incompletely und

116 173Q mutation enhanced viral replication and multinucleated giant cell formation upon infection of rh

117 inding, evidence of actin-based motility and multinucleated giant cell formation were observed betwee

118 correlated with IL-15 treatment and LGC-type multinucleated giant cell formation.

119 miR-7a-1 functions to regulate IL-4-directed multinucleated giant cell formation.

120 he tssE mutants lacked the ability to induce multinucleated giant cell formation.

121 precursors, other cell types can generate a multinucleated giant cell phenotype with bone resorbing

122 Langhans multinucleated giant cells (LGCs) are a specific type of

123 Multinucleated giant cells (MGCs) are implicated in many

124 peritoneal foam cells formed up to 45% more multinucleated giant cells (MGCs) in vitro compared to W

125 rophage fusion resulting in the formation of multinucleated giant cells (MGCs) is a multistage proces

126 The function of osteoclasts (OCs), multinucleated giant cells (MGCs) of the monocytic linea

127 ental macrophages spontaneously matured into multinucleated giant cells (MGCs), a property not exhibi

128 xtensive emperipolesis of lymphocytes within multinucleated giant cells (MGCs), MGC death, and fibrin

129 ound dying adipocytes, and the occurrence of multinucleated giant cells (MGCs).

130 atory lesions, monocytes fuse to form large, multinucleated giant cells (MGCs).

131 ame time promoting macrophage fusion to form multinucleated giant cells (MNG).

132 is is the formation of granulomas containing multinucleated giant cells (MNGCs) and cell death.

133 host cell and to stimulate the formation of multinucleated giant cells (MNGCs).

134 stimulated to limitless differentiation into multinucleated giant cells and provide useful suggestion

135 parenchymal, noncaseating granulomas lacking multinucleated giant cells and, in 1 patient, CD68-posit

136 Multinucleated giant cells are formed by the fusion of m

137 We found that multinucleated giant cells are formed in the inflamed mo

138 Abnormal multinucleated giant cells are present in the bone marro

139 r macrophages that comprise SIVE lesions and multinucleated giant cells are present in the CNS early,

140 ons with numerous SIV-p28(+) macrophages and multinucleated giant cells had fewer MAC387(+) monocytes

141 accumulation of eosinophilic macrophages and multinucleated giant cells in the lung.

142 RAW 264.7 macrophages and was unable to form multinucleated giant cells in this cell line.

143 Cellular fusion of macrophages into multinucleated giant cells is a distinguishing feature o

144 acrophage fusion leading to the formation of multinucleated giant cells is a hallmark of chronic infl

145 rophage fusion resulting in the formation of multinucleated giant cells occurs in a variety of chroni

146 acrophage fusion leading to the formation of multinucleated giant cells remains unclear.

147 fficiently degrade mineralized tissue, these multinucleated giant cells secrete acid into a resorptio

148 Mature osteoclasts are multinucleated giant cells that are generated from the f

149 BI2536-treated LNCaP-AI cells formed multinucleated giant cells that contain clusters of nucl

150 Osteoclasts are multinucleated giant cells that resorb bone, ensuring de

151 from the seminiferous tubules, forming large multinucleated giant cells that underwent apoptosis.

152 The percentage of multinucleated giant cells was lower in brain-injured pa

153 ed microglia in SIV encephalitis lesions and multinucleated giant cells were also CD163 positive.

154 s, parenchymal microglia are infected as are multinucleated giant cells when present.

155 On the remaining surface, multinucleated giant cells with varying intensity of tar

156 granulomatous inflammation characterized by multinucleated giant cells, some of which displayed elas

157 s, confer hyperfusogenicity on HSV and cause multinucleated giant cells, termed syncytia.

158 B. pseudomallei adheres, invades, and forms multinucleated giant cells, ultimately leading to cell t

159 ogy, with disrupted seminiferous epithelium, multinucleated giant cells, uncleared apoptotic germ cel

160 d clearance of amyloid by macrophage-derived multinucleated giant cells.

161 onocytes that transform into macrophages and multinucleated giant cells.

162 d, to a lesser extent, epithelioid cells and multinucleated giant cells.

163 e formation and function of various types of multinucleated giant cells.

164 d fusion of macrophages and the formation of multinucleated giant cells.

165 ted the cells ability to form TRAP positive, multinucleated giant cells.

166 d to the differentiation of macrophages into multinucleated giant osteoclasts and their bone resorpti

167 M) mice) leads to super spread morphology of multinucleated giant osteoclasts with elevated bone reso

168 Endothelial syncytia, comprised of multinucleated giant-endothelial cells, are frequently f

169 Osteoclasts are multinucleated, giant cells of hematopoietic origin form

170 redominantly undifferentiated), induction of multinucleated gonocytes (MNGs), and aggregation of diff

171 organs showed congestions, aggregations and multinucleated hepatocytes in the liver, infiltration of

172 lls (FBGCs) are inflammatory and destructive multinucleated macrophages and may cause damage and/or r

173 Cpd A prevents cytokinesis, resulting in multinucleated, multiflagellated cells that eventually l

174 f proliferating progeny from differentiated, multinucleated muscle cells by first inducing and subseq

175 essary at multiple steps in the formation of multinucleated muscle cells.

176 o system to analyze nuclear scaling in whole multinucleated muscle fibers, genetically manipulate ind

177 es apoptosis of a subset of myonuclei within multinucleated muscle fibers.

178 raveling the intrinsic regulation of size in multinucleated muscle fibers.

179 ation and fusion ability and ultimately form multinucleated "myoballs" rather than maintain elongated

180 toplasmic puncta at the nuclear periphery in multinucleated myoblasts, and that this change in locali

181 ere is also evidence for self-duplication of multinucleated myocytes, suggesting a more complex pictu

182 rsity and whether individual nuclei within a multinucleated myofiber might respond differentially to

183 y cycles of degeneration and regeneration of multinucleated myofibers and pathological activation of

184 ealed an identical phenotype: replacement of multinucleated myofibers by groups of single, myosin-exp

185 Fusion of individual myoblasts to form multinucleated myofibers constitutes a widely conserved

186 eletal muscle, which is composed of numerous multinucleated myofibers formed by the fusion of progeni

187 The formation of multinucleated myofibers is essential for the growth of

188 erved process that leads to the formation of multinucleated myofibers, syncytiotrophoblasts and osteo

189 ell as their differentiation and fusion into multinucleated myofibers, which are greatly reduced in m

190 traction of highly specialized, postmitotic, multinucleated myofibers.

191 n occurs through fusion of myoblasts to form multinucleated myofibers.

192 es fusion of mononucleated myoblasts to form multinucleated myofibers.

193 l muscle development, myoblasts fuse to form multinucleated myofibers.

194 from the fusion of precursor myoblasts into multinucleated myofibres.

195 Multinucleated myotube differentiation was inhibited by

196 also found in the cytoplasm of post-mitotic multinucleated myotubes and adult human skeletal myofibe

197 s stimulated fusion into post-differentiated multinucleated myotubes and the appearance of skeletal a

198 Multinucleated myotubes develop by the sequential fusion

199 hich arise from the fusion of myoblasts into multinucleated myotubes during myogenesis.

200 protein required for myoblast fusion to form multinucleated myotubes in mouse, chick, and zebrafish.

201 fferentiated myotubes, it induced fission of multinucleated myotubes into mononucleated fragments.

202 Myoblast fusion into multinucleated myotubes is a crucial step in skeletal mu

203 Fusion of undifferentiated myoblasts into multinucleated myotubes is a prerequisite for developmen

204 S proteinases contribute to the formation of multinucleated myotubes such as is necessary for both sk

205 During myogenesis, myoblasts fuse into multinucleated myotubes that acquire the contractile fib

206 Here we used primary chicken and duck multinucleated myotubes to examine their susceptibility

207 Conversely, myogenic differentiation into multinucleated myotubes was decreased when Pitx2 or Pitx

208 es fusion of mononuclear progenitors to form multinucleated myotubes, a critical but poorly understoo

209 d that their steady-state levels increase in multinucleated myotubes, suggesting a global increase in

210 ciently drives myogenic differentiation into multinucleated myotubes.

211 ration requires the fusion of myoblasts into multinucleated myotubes.

212 the time when myoblasts were fusing to form multinucleated myotubes.

213 atic myoblasts prior to their fusion to form multinucleated myotubes.

214 dysferlin expression is increased in mature, multinucleated myotubes.

215 myogenesis as individual myoblasts fuse into multinucleated myotubes.

216 he fusion of mononucleated myoblasts to form multinucleated myotubes.

217 ficant differentiation of C2C12 myoblasts to multinucleated myotubes.

218 -fast twitch, myogenin, and the formation of multinucleated myotubes.

219 taining and differentiated successfully into multinucleated myotubes.

220 ry for the proper repair and regeneration of multinucleated myotubes.

221 muscle cells that differentiate into fused, multinucleated myotubes.

222 oles of Notch1 in mononucleated myocytes and multinucleated myotubes.

223 and 66+/-2% MD2 expression in differentiated multinucleated myotubes.

224 with cytokinesis defects attributed to CIT, multinucleated neurons were observed throughout the cere

225 uber-like lesions containing cytomegalic and multinucleated neurons with abnormal dendritic trees res

226 The microcapsules were multinucleated, not very water-soluble or hygroscopic an

227 arrow monocytes (BMMs) to differentiate into multinucleated OCLs in response to exogenously supplied

228 the fusion of OC precursors and formation of multinucleated OCs and decreases bone matrix resorption.

229 equired for RANKL-induced formation of giant multinucleated OCs by up-regulating the expression of nu

230 ved macrophages (BMM), the formation of both multinucleated osteoclast and MNG induced by RANKL or IL

231 BMMs from MCP-1(-/-) mice showed decreased multinucleated osteoclast formation compared with WT mic

232 rived conditioned medium stimulated in vitro multinucleated osteoclast formation.

233 This correlated with fewer multinucleated osteoclast-like cells and more trabecular

234 factor-kappaB ligand, and the appearance of multinucleated osteoclast-like cells in the MPS bone mar

235 id phosphatase staining was used to identify multinucleated osteoclast-like cells.

236 , which increased their differentiation into multinucleated osteoclast-like cells.

237 Fusion is required for the formation of multinucleated osteoclasts and giant cells, although the

238 orm sphingosine 1-phosphate (S1P), in mature multinucleated osteoclasts as compared with preosteoclas

239 ntaining mature osteoblasts and formation of multinucleated osteoclasts in response to BMP-2.

240 ings that Darc-antibody blocked formation of multinucleated osteoclasts in vitro and that Darc from C

241 lls substantially inhibited the formation of multinucleated osteoclasts in vitro.

242 was correlated to the increased activity of multinucleated osteoclasts on the distal side of the mol

243 bone marrow cells fail to differentiate into multinucleated osteoclasts or resorb bone in vitro and s

244 IL1 showed significantly fewer TRAP-positive multinucleated osteoclasts than EP and EP-Saline (P <0.0

245 gand (RANKL), these precursors formed large, multinucleated osteoclasts that expressed tartrate-resis

246 Bone-resorbing multinucleated osteoclasts that play a central role in t

247 KL) resulted in a robust formation of large, multinucleated osteoclasts which generated sealing zones

248 artrate-resistant acid phosphatase-positive) multinucleated osteoclasts, and the osteoclasts were sma

249 Galpha(13) is highly expressed in mature multinucleated osteoclasts, but not during early differe

250 NAs and proteins and impaired fusion to form multinucleated osteoclasts, defects secondary to diminis

251 ow that, while homozygous c-Fos mice have no multinucleated osteoclasts, heterozygous mice have a red

252 nificantly increased during the formation of multinucleated osteoclasts.

253 nsition from mononucleated preosteoclasts to multinucleated osteoclasts.

254 tment with CID755673 and restore fusion into multinucleated osteoclasts.

255 did not completely differentiate into mature multinucleated osteoclasts.

256 at Nf1(+/-) mice contain elevated numbers of multinucleated osteoclasts.

257 (RANKL), as the cells failed to form large, multinucleated osteoclasts.

258 rentiation strongly decreased the numbers of multinucleated osteoclasts.

259 ether, lung cancer cells uniformly grew into multinucleated PGCCs.

260 letion of the NF90/NF45 complex results in a multinucleated phenotype.

261 nable to bind filamin-A failed to induce the multinucleated phenotype.

262 in the absence of cytokinesis, resulting in multinucleated, polyploidy cells.

263 Muscle fibres are multinucleated post-mitotic cells that can change dramat

264 ble cross-over homologous recombination, but multinucleated R. oryzae could not be forced to segregat

265 rvived longer after mitotic arrest, becoming multinucleated rather than dying directly from mitotic a

266 Multinucleated Reed-Sternberg (RS) cells are pathognomon

267 enlarged cardiac myocytes, some of which are multinucleated, reflecting a defect in cytokinesis.

268 ased cell shedding and the presence of large multinucleated RPE cells, suggesting defects in intercel

269 Most mouse cardiomyocytes (CMs) become multinucleated shortly after birth via endoreplication a

270 pletion of CPG-1/CEJ-1 and CPG-2 resulted in multinucleated single-cell embryos.

271 Multinucleated skeletal muscle fibers form through the f

272 Myoblast fusion to form multinucleated skeletal muscle myotubes is a well studie

273 e extent of transcriptional diversity within multinucleated skeletal myofibers.

274 otic null germ cells with many misshapen and multinucleated spermatids, and no spermatozoa are detect

275 immature germ cells, and formation of giant multinucleated spermatids, are commonly detected in test

276 nuclei and reproduce clonally through large multinucleated spores.

277 how cells join together to form zygotes and multinucleated syncytia has remained a fundamental quest

278 A subset of infected cells formed multinucleated syncytia through HIV envelope-dependent c

279 neous fusion of infected cells to form large multinucleated syncytia.

280 ng individual CMV glycoproteins did not form multinucleated syncytia.

281 ell interstitial pneumonitis, accompanied by multinucleated syncytial cells, edema, and bronchiolitis

282 nt is the fusion of trophoblast cells into a multinucleated syncytiotrophoblast (ST) layer.

283 totrophoblasts (CT) ends in formation of the multinucleated syncytiotrophoblast representing the feta

284 subsequently fuse, and differentiate to form multinucleated syncytiotrophoblast with induction of aro

285 hoblasts, including the transcriptome of the multinucleated syncytiotrophoblast.

286 their differentiation potential from TGCs to multinucleated syncytiotropholasts (SynTs) and blocks ox

287 ial layer (YSL) in the zebrafish embryo is a multinucleated syncytium essential for embryo developmen

288 Skeletal muscle is a multinucleated syncytium that develops and is maintained

289 r activator of NF-kappaB ligand formation of multinucleated tartrate-resistant acid phosphatase (TRAP

290 m 50 MF patients showed increased numbers of multinucleated tartrate-resistant acid phosphatase (TRAP

291 y promote preosteoclast cell fusion, forming multinucleated tartrate-resistant acid phosphatase-posit

292 The number of multinucleated tartrate-resistant acid phosphatase-posit

293 tion of transcriptional heterogeneity within multinucleated tissues has been challenging due to the p

294 s and an increase in the formation of giant, multinucleated TRAP(+) cells capable of F-actin ring for

295 expression in mononuclear cells, but not in multinucleated TRAP(+) OC.

296 ar bone loss and reduced the total number of multinucleated TRAP+ cells in mice that received ligatur

297 expressing osteoblasts and reduced number of multinucleated TRAP-expressing osteoclasts.

298 e-marrow precursors that differentiated into multinucleated TRAP-positive cells in the presence of EP

299 MW-E-overexpressing cells are binucleated or multinucleated with amplified centrosomes, whereas EL-ov

300 sors (cathepsin K-positive, mononucleated or multinucleated, within synovial tissue) were also positi