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1 ically complex and energetically challenging multistep reaction.
2 uncovered as the crucial step in a catalytic multistep reaction.
3 te binding conformation in the course of the multistep reaction.
4 lyase to probe the kinetic mechanism of the multistep reaction.
5 62), is loaded onto DNA in an ATP-dependent, multistep reaction.
6 le-stage reactions, materials synthesis, and multistep reactions.
7 thylases) are cytochromes P450 that catalyze multistep reactions.
8 from fragments of complement components via multistep reactions.
9 ing in programmable Hantzsch multicomponent, multistep reactions.
11 s to ORC and the ORC-Cdc6 complex loads in a multistep reaction and, with the help of Cdt1, the core
15 responsible for the progress of the complex multistep reaction as well as for the low rate of cataly
16 wever, they are unsuitable for point-of-care multistep reactions because they sacrifice portability,
17 of the possible substrates formed during the multistep reaction catalyzed by chalcone synthase remain
18 edback' (SNF) model: first, by introducing a multistep reaction chain for posttranscriptional modific
19 frequently obscured in ensemble measures in multistep reactions (i.e., a catalytic cycle consisting
20 les are described, including a novel one-pot multistep reaction in which 2-bromothiazole is treated w
22 Thiopeptide pyridine synthases catalyze a multistep reaction involving a unique and nonspontaneous
23 ure upon binding to their target proteins in multistep reactions involving the formation of both seco
25 titatively revealed the pH dependence of the multistep reaction mechanism and illuminated the roles o
27 nctional theory (DFT) calculations suggest a multistep reaction mechanism that should be generalizabl
29 ami platform is thus suited to study complex multistep reactions occurring over several cycles of enz
30 ubstrate channel diffusion) in the enzymatic multistep reactions of individual PCE-RdhAs rather than
33 ptides, these cross-links are installed in a multistep reaction pathway by a single enzyme (LanM).
36 variants, we probed individual steps in the multistep reaction pathway to determine which processes
39 lves one or more chemical intermediates in a multistep reaction pathway; these may be either isolable
40 e, we designed a kinetic model that includes multistep reaction pathways for cadherin clustering.
41 robalance (QCM) for quantitative analysis of multistep reaction procedures leading to immobilized pro
42 arene (46) were synthesized by two different multistep reaction procedures, the last step of both met
44 ice allows for the execution of user-defined multistep reaction protocols in 95 individually addressa
45 zymes with complex active sites that mediate multistep reactions remains an outstanding challenge.
46 ns have been identified as regulators of the multistep reaction required for endocytosis, including t
47 ecognition of factor X by Xase arises from a multistep reaction requiring an initial interaction at s
48 oint-of-care diagnostic assays often involve multistep reactions, requiring a wide range of precise t
49 composition can interfere with activity, and multistep reactions risk diffusion of intermediates.
50 Hill dose-response curve (FHDC) arise from a multistep reaction sequence, and how do cofactors modify
53 mation involves stoichiometric metals and/or multistep reaction sequences that consume excessive time
55 ionalized BCPs are more commonly prepared by multistep reaction sequences with BCP-halide intermediat
61 is a tightly regulated, highly directional, multistep reaction that is executed by a series of multi
62 we show that in vitro SOD1 aggregation is a multistep reaction that minimally consists of dimer diss
63 ing family of enzymes that catalyze complex, multistep reactions that are capable of generating hundr
64 t involve cloning are inefficient or require multistep reactions that increase the risk of additional
65 ing techniques to construct active sites for multistep reactions, we designed retro-aldolases that us
68 a key role for conformational change in its multistep reaction, which requires a dramatic 180 degree
69 -TTR amyloidogenesis at low pH is a complex, multistep reaction whose kinetic behavior is incompatibl