ライフサイエンスコーパス: murine hepatitis virus

1 rand RNA synthesis in a related coronavirus, murine hepatitis virus.

2 edly increased sensitivity to infection with murine hepatitis virus.

3 efense against a mouse model of coronavirus, murine hepatitis virus-1 (MHV-1) infection of lung.

4 ARS-CoV, SARS-CoV-2, human coronavirus 229E, murine hepatitis virus-1, or MERS-CoV were deposited on

5 colonization inhibits lethal infection with murine hepatitis virus-2, a mouse coronavirus that is de

6 uenza virus hemagglutinin and in variants of murine hepatitis virus, a coronavirus.

7 embranes caught 99.2% of the aerosols of the murine hepatitis virus A59 (MHV-A59), a coronavirus surr

8 two 3CLpro inhibitors in mice infected with murine hepatitis virus A59, a hepatotropic coronavirus,

9 hexameric enzyme from two CoVs, SARS-CoV and murine hepatitis virus, and its monomeric homologue, Xen

10 Theiler's murine encephalomyelitis virus and murine hepatitis virus, are used to induce infectious mo

11 expressed from the replicase polyprotein of murine hepatitis virus as fusions with nonstructural pro

12 ocations within the replicase polyprotein of murine hepatitis virus as fusions with nonstructural pro

13 gative, temperature-sensitive (ts) mutant of Murine hepatitis virus, Bristol ts31 (MHV-Brts31), that

14 Here, we show that for the coronavirus murine hepatitis virus, cleavage between the nonstructur

15 bstitutions at homologous nsp12 positions in murine hepatitis virus demonstrated transferability acro

16 Our results support the hypothesis that murine hepatitis virus ExoN activity is required for res

17 esicular stomatitis virus infection, but not murine hepatitis virus infection.

18 ng, we show that during acute infection with murine hepatitis virus, MHC class I is expressed in vivo

19 Here, we demonstrate that NHC inhibits both murine hepatitis virus (MHV) (50% effective concentratio

20 g the 5B19 epitope from the spike protein of murine hepatitis virus (MHV) and giving rise to TMV-5B19

21 s (AA-E-D; four nucleotide substitutions) in murine hepatitis virus (MHV) and severe acute respirator

22 Murine hepatitis virus (MHV) and severe acute respirator

23 uses, Mac1 was shown to be critical for both murine hepatitis virus (MHV) and severe acute respirator

24 introduced alanine substitutions in nsp14 of murine hepatitis virus (MHV) at the nsp14-nsp10 interfac

25 Overall, our data suggest murine hepatitis virus (MHV) ExoN activity is required f

26 Murine hepatitis virus (MHV) gene 1, the 22-kb polymeras

27 Murine hepatitis virus (MHV) has long served as a model

28 We have used several strains of murine hepatitis virus (MHV) in cell culture and in vivo

29 revertants of a severely defective mutant of murine hepatitis virus (MHV) in which the N gene was rep

30 To determine the requirement of nsp4 for murine hepatitis virus (MHV) infection in culture, engin

31 Murine hepatitis virus (MHV) infection provides a model

32 by its function in the context of a related murine hepatitis virus (MHV) infection.

33 Murine hepatitis virus (MHV) infections exhibit remarkab

34 alanine replacements were engineered into a murine hepatitis virus (MHV) infectious clone in place o

35 The prototype JHM strain of murine hepatitis virus (MHV) is an enveloped, RNA-contai

36 at PARP12 might inhibit the replication of a murine hepatitis virus (MHV) Mac1 mutant virus in bone-m

37 replication, we compared the replication of murine hepatitis virus (MHV) Mac1 mutants, D1329A and N1

38 We modeled the CoV murine hepatitis virus (MHV) nsp12-RdRp structure and su

39 Here, we engineered mutations in murine hepatitis virus (MHV) nsp14 N7-MTase at residues

40 hip between the endoribonuclease activity of murine hepatitis virus (MHV) Nsp15 (mNsp15) and its role

41 has been shown previously that mutations in murine hepatitis virus (MHV) nsp4 loop 1 that alter nsp4

42 Using reverse genetic mutagenesis of the CoV murine hepatitis virus (MHV) nsp5, we identified a new t

43 The envelopes of murine hepatitis virus (MHV) particles are studded with

44 Murine hepatitis virus (MHV) PLP2 and orthologs recogniz

45 and indeed, 27 inhibited replication of both murine hepatitis virus (MHV) prototypes CoV and SARS-CoV

46 o nsp10 proteins and their processing during murine hepatitis virus (MHV) replication.

47 abies virus (RV) glycoprotein, and 5B19 from murine hepatitis virus (MHV) S-glycoprotein were success

48 activity tested according to ISO-18184 with murine hepatitis virus (MHV) showed > 99% viral reductio

49 The Murine hepatitis virus (MHV) strain A59 ns2 protein is a

50 known temperature-sensitive (TS) mutants of murine hepatitis virus (MHV) strain A59, proposes that a

51 Sequencing and reversion analysis of murine hepatitis virus (MHV) temperature-sensitive (ts)

52 Murine hepatitis virus (MHV), a coronavirus, initiates i

53 on of several PARPs following infection with murine hepatitis virus (MHV), a model coronavirus.

54 l recombination event involving RCoV-GCCDC4, murine hepatitis virus (MHV), and Longquan Rl rat corona

55 In murine hepatitis virus (MHV), nsps 1, 2, and 3 are proce

56 For the betacoronavirus murine hepatitis virus (MHV), total inhibition of transl

57 ly increases replication fidelity of the CoV murine hepatitis virus (MHV).

58 uring infection by the enveloped coronavirus murine hepatitis virus (MHV).

59 man coronaviruses (hCoV-229E, hCoV-Oc43) and murine hepatitis virus (MHV-A59) at non-cytotoxic concen

60 ne substitution mutations into the genome of murine hepatitis virus (MHV-A59) containing ExoN activit

61 to neutralize the neurotropic JHM strain of murine hepatitis virus (MHV-JHM).

62 ctivation of two enveloped viruses (Phi6 and murine hepatitis virus, MHV) and a nonenveloped virus (M

63 ac1 proteins and recombinant CoVs, including murine hepatitis virus, Middle East respiratory syndrome

64 Here we show that for the coronavirus murine hepatitis virus, nsp14 residues at the nsp14-nsp1

65 In this report, we show that the murine hepatitis virus nsp2 sequence was tolerated in OR

66 ity, efficiently suppressed Sendai virus and murine hepatitis virus replication.

67 Direct ligation of T cells in vitro with the murine hepatitis virus spike protein, a natural ligand f

68 Infection of mice with murine hepatitis virus strain 1 (MHV-1), a mouse coronav

69 We used murine hepatitis virus strain 1 (MHV-1), a mouse coronav

70 isease model through infecting A/J mice with murine hepatitis virus strain 1 (MHV-1), we show that i.

71 nt murine coronaviruses expressing wild-type murine hepatitis virus strain 4 (MHV-4) or MHV-A59 spike

72 were tested against two model coronaviruses: murine hepatitis virus strain A59 (MHV) and human corona

73 The murine hepatitis virus strain A59 (MHV-A59) model produc

74 for inactivating murine coronaviruses (i.e., murine hepatitis virus strain A59 (MHV-A59)) by 2.17-4.6

75 ceptible to high-fat diet-caused obesity and murine hepatitis virus strain-3 (MHV-3)-induced fulminan

76 es in vivo during infection with a strain of murine hepatitis virus that causes a chronic, inflammato

77 to primary and/or secondary challenges with murine hepatitis virus type 1 (MHV-1) were analyzed.