ライフサイエンスコーパス: muscimol

1 to 8.9 +/- 0.9 (insulin), then 5.1 +/- 0.5 (muscimol)).

2 ) receptor (GABA(A)R) responses, elicited by muscimol.

3 icroinfusion of the GABA-A receptor agonist, muscimol.

4 ation and desensitization in the presence of muscimol.

5 used by medial septum (MS) inactivation with muscimol.

6 less of whether its retrieval was blocked by muscimol.

7 imulated motor cortex using the GABA agonist muscimol.

8 lus (predator stress) altered sensitivity to muscimol.

9 poxide, a benzodiazepine (2.5-5 microg), and muscimol (0.05-5 ng).

10 r (ii) activation of central GABA(A)R by i.c muscimol (0.1 mug/rat).

11 ral injection of the GABA-A receptor agonist muscimol (0.1 nmol in 50 nl).

12 nhibition of neurons in LPBN area (n=6) with muscimol (0.45 nmol per side) reduced dorsal PAG-evoked

13 1.7 g +/- 0.48) by simultaneous infusions of muscimol (0.6 mM/100 nl) into the IRt/PCRt (p < .01).

14 roinjections (100 nl) of the GABA(A) agonist muscimol (1 mm), induced the following: (1) a massive cu

15 icroinjections of the GABA agonists baclofen/muscimol (1/0.1 mM) into unilateral PL and the AMPA rece

16 reversible inactivation techniques (baclofen/muscimol: 1.0/.1 mmol/L, .3 muL/side).

17 tra-Acb shell infusion of the GABAA agonist, muscimol (10 ng).

18 ent by D1 (SKF38393; 100ng/side) or GABA(A) (muscimol; 100ng/side) receptor agonists in ovariectomize

19 , ethanol (up to 50 mM) did not affect [(3)H]muscimol (15 nM) binding to the immunoprecipitated delta

20 Microinjection of the GABA agonist muscimol (250 pmol) into the caudal ventrolateral periaq

21 Ethanol (1-50 mM) neither affected [(3)H]muscimol (3 nM) binding nor diazepam-insensitive [(3)H]R

22 Phase shifts (mean +/- S.E.M., h) in muscimol/8-OH-DPAT-microinjected hamsters (1.02 +/- 0.30

23 Muscimol (80 pmol), a GABA(A) agonist, or losartan (43.4

24 t 1, hamsters received DRN pretreatment with muscimol (87.6 pmol) or vehicle before DRN 8-OH-DPAT (6

25 ized rats before and after microinjection of muscimol (9 nl; 0.25 mM), a GABA-A receptor agonist, int

26 lonidine (an alpha-2 adrenergic agonist) and muscimol (a GABAa agonist) induce an inhibition of PS.

27 onjugate consisting of approximately 150-200 muscimols (a GABA receptor agonist) covalently joined to

28 Muscimol, a GABA agonist, inactivated part of the OMV, w

29 Muscimol, a GABA agonist, was used to inactivate the pre

30 We injected muscimol, a GABA(A) agonist, and manganese, a magnetic r

31 thyl)-1-hydroxypyrazole (4-AHP) analogues of muscimol, a GABA(A) receptor agonist, has been synthesiz

32 Bilateral injections of muscimol, a GABAA agonist, into the mPFC significantly d

33 us using infusions of fluorophore-conjugated muscimol, a GABAA agonist.

34 receptor subunit gamma2 (TAT-GABAgamma2) and muscimol, a GABAA receptor agonist.

35 The treatment with muscimol, a gamma amino butyric acid receptor-A (GABA(A)

36 esponses by microinjecting artificial CSF or muscimol, a neuronal inhibitor, into the DMH prior to in

37 Low concentrations (0.1-0.3 microm) of muscimol, a selective GABA(A)R agonist, increased the am

38 Injections of muscimol abolished the amplitude increase adaptation of

39 These data point to a presynaptic locus of muscimol action.

40 naptic-type GABA(A) receptors, both THIP and muscimol additionally exhibited, to different degrees, s

41 nd behavioral studies have demonstrated that muscimol administered through the cranial meninges can p

42 However, it has not been proved that muscimol administered via the transmeningeal route can p

43 vation of the primary motor cortex (M1) with muscimol affected anticipatory patterns in S1 and the th

44 Microinjection of muscimol alone modestly decreased baseline HR and MAP bu

45 Muscimol also impaired response control (increased prema

46 Muscimol, an agonist at GABA(A) receptors, produced a la

47 We injected either muscimol, an agonist of GABA, to inactivate the OMV or b

48 Using (3)H-muscimol and (3)H-flunitrazepam we could determine wheth

49 lation the activity of three agonists, GABA, muscimol and 4,5,6,7-tetrahydoisoxazolo[5,4-c]pyridin-3(

50 dorsomedial striatum using the GABA agonists muscimol and baclofen decreased context-induced reinstat

51 In most cases tested, the effects of muscimol and baclofen remained similar when synaptic tra

52 ivation (achieved by presession injection of muscimol and baclofen) in a novel two-reward choice task

53 sponses in NG2 cells, which were mimicked by muscimol and inhibited by bicuculline.

54 GABA and the GABA(A) agonists muscimol and isoguvacine enhanced isolated chloride curr

55 ction time (5CSRT) test, we showed that both muscimol and picrotoxin impaired attention (reduced accu

56 Based on muscimol and tetrodotoxin microinfusions, these glutamat

57 A 50 muL mixture of [(3)H] muscimol and unlabeled muscimol with a final concentrati

58 al circuits using the GABAA receptor agonist muscimol and validated the lesion placement using MRI.

59 /- double knockout, CBS-/+ mice treated with muscimol and wild type (WT) mice.

60 class (e.g., pentobarbital, chloral hydrate, muscimol, and ethanol) produce analgesia and unconscious

61 After injections of either saline or muscimol, animals consumed more of the 0.29 M than the 0

62 bjects, quadrupedal rotations were evoked by muscimol application into SNpr sites that were distinct

63 Muscimol at 5.0mM also prevented seizures, but decreased

64 After injection of muscimol at rostral sites in the dSC, fixation became mo

65 mediate shock; and (2) BLA inactivation with muscimol attenuated the increase in Arc and c-fos mRNA i

66 of the medial prefrontal cortex by baclofen/muscimol (B/M) during testing attenuates renewal when te

67 Additionally, renewal was blocked by muscimol + baclofen injections into LH.

68 Injections of muscimol + baclofen into ventral mPFC in one hemisphere

69 Unilateral injections of muscimol + baclofen into ventral mPFC or SCH 23390 into

70 tivation by GABAA + GABAB receptor agonists (muscimol + baclofen) on this effect.

71 on of GABA(A) and GABA(B) receptor agonists (muscimol + baclofen) to show a causal role of the AI in

72 hell by either GABA(A) and GABA(B) agonists (muscimol + baclofen, 50 + 50 ng/side), Drd1-Drd2 antagon

73 NAc core, but not shell, injections of muscimol + baclofen, flupenthixol, SCH39166, and raclopr

74 Muscimol+baclofen injections into CeA but not BLA decrea

75 Muscimol+baclofen injections into dmPFC, vmPFC, or OFC d

76 We also assessed the effect of muscimol+baclofen reversible inactivation of vmPFC, dmPF

77 ivated the vSub with GABA receptor agonists (muscimol+baclofen) before the context-induced relapse te

78 CeA or BLA by GABAA+GABAB receptor agonists (muscimol+baclofen, 0.03+0.3 nmol) on cue-induced methamp

79 Conversely, CeA inhibition by muscimol/baclofen microinjections prevented acquisition

80 Interestingly, in CBS-/+ mice treated with muscimol, BBB permeability was significantly decreased c

81 inactivated by infusion of the GABA agonist muscimol before acute stressor exposure.

82 Hippocampal inactivation with muscimol before retention testing disrupted discriminati

83 Females infused with muscimol before stress did not express a deficit in cond

84 Males infused with muscimol before the stressful event did not exhibit faci

85 as bilaterally inactivated with GABA agonist muscimol before the stressor.

86 the effects of single DRN microinjections of muscimol, bicuculline (136 pmol), NMDA, MK-801 (10 pmol)

87 he brain, and studies of modulation of [(3)H]muscimol binding by allosteric GABAergic modulators such

88 accurately predicts the enhancement of [(3)H]muscimol binding in the presence of the potentiating ste

89 The model predicts enhancement of [(3)H]muscimol binding in the presence of the steroids allopre

90 angeux concerted transition model to analyze muscimol binding isotherms.

91 selectivity for the [(3)H]NCS-382 over [(3)H]muscimol binding sites.

92 delta-subunit of GABA(A) receptors and [(3)H]muscimol binding to the immunoprecipitated delta-subunit

93 in the rat cerebellum as determined by [(3)H]muscimol binding to the immunoprecipitated receptor asse

94 Inactivation of NRM with muscimol blocked ingestion analgesia during NaCl ingesti

95 application of the GABA(A) receptor agonist muscimol blocked spontaneous correlated increases in int

96 Coapplication of GABA or muscimol, but not of gabazine, with MTSES prevented the

97 we microinfused the GABA-A receptor agonist muscimol (C4H6N2O2; 62.5, 125, 250 ng/side) or antagonis

98 This study provided evidence that muscimol can be delivered via the transmeningeal route i

99 the hypothesis that epidurally administered muscimol can prevent acetylcholine (Ach)-induced focal s

100 fusion of muscimol or fluorophore-conjugated muscimol caused a near complete shift in preference from

101 cells, GABA and the GABA(A) receptor agonist muscimol caused a rapid and transient increase in intrac

102 Muscimol caused a significant increase in wakefulness an

103 Muscimol caused all ipsiversive horizontal saccades from

104 It is interesting that 1 microm muscimol caused an inhibition of sIPSCs, which was rever

105 Deactivation of the MnPN with muscimol caused opposite effects.

106 At this muscimol concentration, the average baseline multineuron

107 of cells in the PVT with the GABA(A) agonist muscimol could alter food intake in non-deprived rats.

108 In contrast, muscimol decreased CS synchrony.

109 FC neurons with the GABA agonists baclofen + muscimol decreased cue-induced heroin seeking on withdra

110 ebral infusion of the GABAA receptor agonist muscimol decreased the number of new HVC neurons by 56%.

111 It was proposed that transmeningeal muscimol delivery can be used for the treatment of intra

112 pendent inactivation of either BM or BL with muscimol did not cause a reduction of conditioned freezi

113 ons of the gamma aminobutyric acid-A agonist muscimol did not impair acquisition of the odor discrimi

114 Results showed that (1) [(3)H] muscimol diffused through the meninges into the cortical

115 Muscimol disrupted both retrieval of pups and nursing be

116 esponse to these two distinct stressors, rPH muscimol disrupted habituation to each stressor modality

117 icate that auditory thalamic inactivation by muscimol disrupts acute HPA axis response specifically t

118 In addition, muscimol dose dependently reduced open-field locomotor a

119 GO (2.5 mug) also sensitized intra-Acb shell muscimol-driven feeding.

120 e CE of rabbits (Oryctolagus cuniculus) with muscimol during NMR conditioning and/or during US testin

121 GABA and muscimol each increased MTSEA-Biotin modification of alp

122 evented the effect, suggesting that GABA and muscimol elicit a conformational change that reduces acc

123 Whereas the GABAA receptor agonist muscimol evoked excitatory, inhibitory, or mixed effects

124 However, postsynaptic muscimol-evoked GABA(A) responses remained intact.

125 rized during the preictal phase, whereas the muscimol-evoked GABA(A) reversal potential remained unch

126 ound that 3alpha,5alpha-THP-, SKF38393-, and muscimol-facilitated lordosis was attenuated by infusion

127 Although muscimol failed to change reflex micturition when microi

128 pports the rationale of using transmeningeal muscimol for the treatment of intractable focal neocorti

129 Muscimol (GABA-A agonist) injection in or next to the so

130 of D-AP5 (glutamate receptor antagonist) and muscimol (GABAA receptor agonist) in the SubC virtually

131 The agonists GABA and muscimol gave EC50 values of 278 mum and 182 mum, respec

132 VN, newborn cells did not survive in the UVN-muscimol group whereas the number of GABAergic pre-exist

133 Consistent with previous studies, muscimol had no effect in EH rats (n = 6), but reduced m

134 Muscimol had no effect in rats with an intact contralate

135 The binding of [(3)H]muscimol has been used to evaluate the distribution of G

136 Muscimol has potent antiepileptic efficacy after transme

137 Pu with GABA receptor agonists (baclofen and muscimol) immediately prior to reinstatement testing.

138 Inhibiting activity with the GABA(A) agonist muscimol impaired DMTP.

139 Inactivating CGp with muscimol impaired new learning when rewards were small b

140 These data indicate that transmeningeal muscimol in a submillimolar concentration range can prev

141 sed by DAMGO microinjection and decreased by muscimol in CeA.

142 s and increased the affinity for the agonist muscimol in human alpha1beta2/3gamma2L GABA(A) receptors

143 : inhibition of DLSC attenuated CD evoked by muscimol in SNpr in all four animals.

144 Finally, we used muscimol in the barrel cortex to silence the corticothal

145 PL-IL or OFC infusion with the GABA agonist muscimol in the context of 2 flexible responding tasks:

146 Increasing GABAA transmission with muscimol in the dorsal and ventral mPFC attenuated relap

147 l cortex that are differentially affected by muscimol inactivation of medial septum.

148 epresentations in a novel environment during muscimol inactivation of the medial septal area, a manip

149 Muscimol inactivation of the medullary raphe magnus bloc

150 Muscimol inactivation of the PL/IL never impaired switch

151 formal algorithmic behavioral analysis with muscimol inactivation, we provide causal evidence direct

152 ma-aminobutyric acid type A (GABA-A) agonist muscimol increased GSWD occurrence up to 37-fold, wherea

153 Moreover, muscimol increased the frequency but not the amplitude o

154 e gamma-aminobutyric acid A (GABAA) agonist, muscimol, indeed activate locomotion.

155 nt alpha-Ctx, however, could be displaced by muscimol indicating that most of the alpha-Ctx-binding s

156 In contrast, the GABA(A) agonist, muscimol, induced general disruptions to behaviour.

157 Furthermore, similar to U0126, baclofen+muscimol-induced (B+M; 106.8/5.7 ng/0.5 mul/hemisphere)

158 xposure to sweetened fat robustly sensitized muscimol-induced feeding.

159 Furthermore, bilateral muscimol-induced inactivation of the VP abolished the re

160 to restore MAP (n = 5), suggesting that the muscimol-induced reduction of cardiac rhythmic sSNA in D

161 Muscimol infused intra-CA1 before an extinction training

162 r impaired performance, and both saline- and muscimol-infused rats appeared to use immediate task con

163 In kittens, we inactivated motor cortex by muscimol infusion between postnatal weeks 5 and 7.

164 Muscimol infusion into medial septum reduced the probabi

165 strategy switches but not reversals, whereas muscimol infusion into OFC impaired retention of reversa

166 Muscimol infusion into PL-IL impaired retention of strat

167 rm retention of the trace eyeblink CR, using muscimol infusion to reversibly inactivate the IP nucleu

168 ally inactivated M1 between weeks 5 and 7 by muscimol infusion.

169 Inactivating the interpositus nucleus with muscimol infusions abolished these conditioned responses

170 In contrast, intra-vmPFC muscimol infusions did not alter the overall intake of c

171 ar surgery and training except they received muscimol infusions immediately before devaluation testin

172 er this treatment would prevent CD evoked by muscimol infusions in SNpr.

173 Muscimol infusions into the AIC diminished intake, total

174 Non-defeated animals receiving muscimol infusions prior to testing with a non-aggressiv

175 ns were necessary for duration judgments, as muscimol infusions produced a specific impairment in ani

176 with striatal gamma activity, and intra-BLA muscimol infusions selectively reduced striatal gamma po

177 ted through amygdala temporary deactivation (muscimol infusions), which rescued the depressive-like b

178 th in vivo electrophysiology, we showed that muscimol inhibited prefrontal firing, whereas picrotoxin

179 Muscimol injection into commissural part of the solitary

180 Muscimol injection into the rostral ventral respiratory

181 Our previous study showed that muscimol injections cause ipsiversive saccades to fall s

182 Intra-MR muscimol injections did not alter the within burst rate

183 itory thalamus was inactivated reversibly by muscimol injections during repeated loud noise exposures

184 In contrast, intra-MR muscimol injections had little effect on the initial lic

185 eted subjects avidly consumed this solution, muscimol injections had no effect either on the volume c

186 Furthermore, after muscimol injections in the LH, the VLPAG/dDpMe contained

187 s near optimally, even after large bilateral muscimol injections into MSTd.

188 approach involving inactivation of the BG by muscimol injections into the caudate nucleus of monkeys

189 We found that muscimol injections into the central PVT dose-dependentl

190 esent experiment investigated the effects of muscimol injections into the rat dorsal anterior cingula

191 ques to characterize the effects of intra-MR muscimol injections on the consumption of either a 0.05

192 gestive behavior, we examined the effects of muscimol injections on the intake of a 3% NaCl solution

193 Muscimol injections produced a significantly larger incr

194 In contrast, in these same animals, muscimol injections significantly increased licking of a

195 in two macaques (Macaca mulatta) with local muscimol injections.

196 ibition of the contralateral intact RTN with muscimol instantly eliminated phrenic nerve discharge (P

197 by infusions of the GABA(A) receptor agonist muscimol into area 13 blocked the devaluation effect: th

198 In contrast, infusions of muscimol into Gi had no discernible effect on food intak

199 Microinjections of the GABAA agonist muscimol into PVN inhibit both basal and meningeal-evoke

200 cent area with microinjections of glycine or muscimol into rRPa.

201 were reversibly abolished by an infusion of muscimol into the cerebellar interpositus nucleus.

202 of microinjection of the neuronal inhibitor muscimol into the DMH on increases in HR, MAP and T(co)

203 Microinjecting muscimol into the DMH prior to MDMA prevented increases

204 re virtually abolished by prior injection of muscimol into the DMH.

205 In contrast, microinjection of muscimol into the hypothalamic paraventricular nucleus f

206 To test this, we infused the GABAA agonist muscimol into the IC and the mu-opioid receptor antagoni

207 Infusions of the GABA(A) agonist muscimol into the LS prior to testing significantly incr

208 n that microinjections of the GABA-A agonist muscimol into the median raphe nucleus (MR) result in la

209 rebrospinal fluid control, microinjection of muscimol into the MnPN resulted in significantly higher

210 the gamma-aminobutyric acidA (GABAA) agonist muscimol into the nucleus accumbens shell (AcbSh) induce

211 lso observed food intake after injections of muscimol into the overlying ventricle or laterally adjac

212 Infusion of the GABAA agonist muscimol into the VM also reduced MCx-SNpr coherence and

213 0 into the accumbens and the GABA(A) agonist muscimol into ventral pallidum (i.e., "disconnection" me

214 mM solutions of a GABA(A) receptor agonist, muscimol, into the MnPN on Fos expression (Fos-IR) in th

215 Muscimol is a psychoactive isoxazole derived from the mu

216 0 to 198 +/- 24 (insulin), then 133 +/- 23 (muscimol) LSNA gain in % control mmHg-1: from 3.9 +/- 0.

217 Muscimol-mediated excitatory actions were found in a nom

218 Muscimol-mediated inactivation of the vmPFC, and intra-v

219 ability-driven feeding was carried out after muscimol-mediated inactivation of two frontal regions in

220 We unilaterally inactivated M1 by muscimol microinfusion between postnatal weeks 5 and 7 t

221 using unit recordings and inactivation with muscimol microinfusions in rats.

222 he current studies, we used intrahippocampal muscimol microinfusions to transiently inactivate the ma

223 Conversely, inactivation of CeA by muscimol microinjection (0.25 microg) suppressed approac

224 ition of LSr neurons with local baclofen and muscimol microinjection (0.3/0.03 nmol) blocks expressio

225 Muscimol microinjections into a nearby region, the nucle

226 the blood brain permeability; treatment with muscimol mitigated BBB permeability.

227 By contrast, for muscimol, moderate superagonist behaviour was caused by

228 ze, we demonstrated in rats that a bilateral muscimol (MSCI) inactivation (0.70 vs 0.26 and 0 nmol) o

229 Bilateral muscimol (MUS) injections into either the hippocampus or

230 hicle control), the GABA(A) receptor agonist muscimol, muscimol with the GABA(A) receptor antagonist

231 d qdots and PEG-qdots that lacked conjugated muscimol neither exhibited significant binding activity

232 ngle microinjections of bicuculline, but not muscimol, NMDA, or MK-801 induced phase advances.

233 After many switches, however, muscimol no longer impaired performance, and both saline

234 Experiment 3 examined whether the effects of muscimol on aggression were dependent on prior social de

235 o a different class, mimicked the effects of muscimol on sIPSCs: it increased them at low (<or= 0.5 m

236 ural parameters suggested that the effect of muscimol on sucrose intake was not mediated by alteratio

237 h infusion of the GABA agonists baclofen and muscimol, on place acquisition and reversal learning.

238 Systemic muscimol or baclofen are antipruritic against both hista

239 GABA-A and GABA-B receptors, the effects of muscimol or baclofen were studied.

240 thermore, CeA inactivation induced by either muscimol or CRF ASO administration immediately before re

241 or thalamic nuclei (ATN) by microinfusion of muscimol or fluorophore-conjugated muscimol caused a nea

242 etinal activity by intraocular injections of muscimol or gabazine during this period did not alter th

243 exogenously applied GABA(A) receptor agonist muscimol or glycine, either of which under control condi

244 ects of injecting the GABAA receptor agonist muscimol or the GABAA receptor antagonist bicuculline in

245 cular infusions of saline, GABA(A)R agonist (muscimol) or antagonist (gabazine), cell proliferation a

246 nd IL-31Tg mice with combinations of GABA-A (muscimol) or GABA-B (baclofen) receptor agonists 15 to 2

247 diazoxide plus the GABA(A) receptor agonist muscimol, or 5) glybenclamide plus the GABA(A) receptor

248 Rats microinjected with ibotenic acid, muscimol, or a CRF ASO into the CeA before contextual fe

249 Unilateral microinjections of lidocaine, muscimol, or glutamate antagonists into the pTRG inhibit

250 stimuli were neutral, infusion of the GABAA, muscimol, or the NMDA receptor (NMDAR) antagonist ifenpr

251 the application of the high-affinity agonist muscimol partially rescued rapid desensitization compare

252 units) and investigated the binding of this muscimol-PEG-qdot conjugate to homomeric rho1 GABAC rece

253 Upon 5- to 10-min incubation with muscimol-PEG-qdots (34 nM in qdot concentration), GABAC-

254 ity nor diminished the subsequent binding of muscimol-PEG-qdots.

255 Pharmacological inactivation of the OFC with muscimol plus baclofen (50 + 50 ng/side) decreased relap

256 Pharmacological inactivation of the Pir with muscimol plus baclofen decreased relapse to fentanyl see

257 to the Pir in one hemisphere plus unilateral muscimol plus baclofen injections into the OFC in the co

258 Unilateral muscimol plus baclofen injections into the Pir in one he

259 Saline and muscimol pretreatment in the concentration range of 0.00

260 information transfer via Te2 inhibition with muscimol prevents any retrieval-evoked neuronal activity

261 inobutyric acid A (GABA(A)) receptor agonist muscimol, prior to a hypoglycemic clamp or under baselin

262 The case is made that muscimol probably caused a hyperexcitation of VTA DA neu

263 combined subthreshold doses of baclofen and muscimol produced a significant synergistic antipruritic

264 Inactivation of the MD with muscimol produced rightward shifts in peak pressing on p

265 rates were significantly suppressed, whereas muscimol raised glucose infusion rates significantly com

266 Muscimol reduced and picrotoxin enhanced bursting and bo

267 Muscimol reduced burst frequency of phrenic nerve activi

268 activation of the CeA with the GABAA agonist muscimol reduced DAMGO (D-Ala2-NMe-Phe4-Glyol5-enkephali

269 In contrast, 0.5-mM muscimol reduced the average EEG Seizure Duration Ratio

270 (2) [(3)H] muscimol-related autoradiography grains were distributed

271 (3) [(3)H] muscimol-related autoradiography grains were localized t

272 In contrast, intra-MD injections of muscimol resulted in a potent dose-dependent suppression

273 ma-aminobutyric acid receptor type A agonist muscimol resulted in an impairment only when BLA was ina

274 and baseline food intake, whereas intra-BLA muscimol selectively blocked only DAMGO-induced food int

275 th bilateral injections of the GABAA agonist muscimol, selectively blocked the expression of SFiA whi

276 g with the obtained SAR indicate that 2a and muscimol share a common binding mode, which deviates fro

277 Muscimol significantly increased EEG power in the delta

278 After a 1-hour exposure, the muscimol solution was removed and replaced with formalin

279 ther focal RF infusions of the GABAA agonist muscimol suppressed eating.

280 he resting condition, a dose of baclofen and muscimol that blocked a behaviorally induced increase in

281 introduce a paramagnetic analog of the drug muscimol that enables targeted neural inactivation to be

282 Microinjections of glutamate and muscimol to activate or inhibit neuronal cell bodies in

283 SC of four macaques with the GABA(A) agonist muscimol to determine whether this treatment would preve

284 initial training, rats received infusions of muscimol to inactivate the pDMS immediately before sessi

285 f avoidance training, rats were infused with muscimol to pharmacologically inactivate the prelimbic c

286 unctional studies to describe the binding of muscimol to the receptor.

287 macaques by intracerebral microinjection of muscimol (to inactivate) or bicuculline (to activate) to

288 striatum was infused with saline or baclofen/muscimol, to temporarily inactivate the region.

289 + neurons in the PF-LHA did not change after muscimol treatments.

290 Picrotoxin or muscimol was applied to the cerebellar cortex at the bor

291 ther saline or 0.005-, 0.05-, 0.5- or 5.0-mM muscimol was delivered through the cup, followed by a 20

292 Furthermore, facilitation of sIPSCs by muscimol was eliminated in a medium containing tetrodoto

293 When muscimol was infused after satiation and therefore, BLA

294 tified, exposure of 1900 or fewer neurons to muscimol was sufficient to sustain whole-body general an

295 Muscimol was used to temporarily inhibit the DHC and was

296 The dose of muscimol we used produces strong contralateral but no ip

297 hypothesis, GABA receptor agonists (baclofen/muscimol) were microinjected into the anterior cingulate

298 hypothalamic injections of small volumes of muscimol, which disrupts normal synaptic functions, befo

299 tal cortex with the GABA(A) receptor agonist muscimol, which eliminates the protective effects of con

300 muL mixture of [(3)H] muscimol and unlabeled muscimol with a final concentration of 1.0mM was deliver

301 rol), the GABA(A) receptor agonist muscimol, muscimol with the GABA(A) receptor antagonist bicucullin