ライフサイエンスコーパス: muscle fiber

1 ant populations, which fuse with the injured muscle fiber.

2 with microscopic core-like structures in the muscle fiber.

3 Cl-free challenge, for an isolated skeletal muscle fiber.

4 JPH1 recruitment at triads in adult skeletal muscle fibers.

5 synthesized JPHs at triads in adult skeletal muscle fibers.

6 trolene to inhibit Ca(2+) release in skinned muscle fibers.

7 ting of aggregated laminae of unidirectional muscle fibers.

8 find unexpected roles for distinct planarian muscle fibers.

9 nd in atrophy especially in the case of slow muscle fibers.

10 surface and in close proximity to the mature muscle fibers.

11 ), which form the connection between MNs and muscle fibers.

12 on, and mitochondrial structure in diaphragm muscle fibers.

13 mtDNA deletions by mitophagy in postmitotic muscle fibers.

14 aments, similar to what has been observed in muscle fibers.

15 at 199 miRNAs identified in the two types of muscle fibers.

16 located parts, and efferents also innervate muscle fibers.

17 mportant to ensure the cell/matrix anchor of muscle fibers.

18 anes, causing disorganization of regenerated muscle fibers.

19 nce training increased its content in type I muscle fibers.

20 ation to the accumulation of glycogen in the muscle fibers.

21 y impaired myogenic capacity in regenerating muscle fibers.

22 d the expression of the NOTCH ligand JAG2 in muscle fibers.

23 including blood vessels, motor neurons, and muscle fibers.

24 mechanics of either fully active or resting muscle fibers.

25 trophic factors, controls the properties of muscle fibers.

26 actomyosin crossbridge formation in skeletal muscle fibers.

27 levels of nuclear factors in differentiated muscle fibers.

28 cise-mediated glucose uptake in nonoxidative muscle fibers.

29 macrophages are likely involved in damaging muscle fibers.

30 shold MNs innervating fatigue resistant slow muscle fibers.

31 ptic motor neuron and multiple post-synaptic muscle fibers.

32 nza A viruses to replicate in avian skeletal muscle fibers.

33 to repair damaged muscle fibers or form new muscle fibers.

34 thelial tumors by wrapping around vessels or muscle fibers.

35 ive oxygen species production in G2435R-RYR1 muscle fibers.

36 dly divided into slow-twitch and fast-twitch muscle fibers.

37 meric bZIP transcription factors in skeletal muscle fibers.

38 ng transcription factor 4 (ATF4) in skeletal muscle fibers.

39 mpening of inflammation, and regeneration of muscle fibers.

40 ng oxygen consumption rates in permeabilized muscle fibers.

41 e RyR1 Ca(2+) leak in human skinned skeletal muscle fibers.

42 titative measurement of dystrophin in murine muscle fibers.

43 ces and cytosolic calcium dynamics of single muscle fibers.

44 re assessed in saponin-permeabilized cardiac muscle fibers.

45 that result in lipid accumulation in injured muscle fibers.

46 aintain the physiological orientation of the muscle fibers.

47 eled at specific sites with BSLs in oriented muscle fibers.

48 trinsic regulation of size in multinucleated muscle fibers.

49 pport the contractile properties of maturing muscle fibers.

50 eveal that the Kbtbd5 null mice have smaller muscle fibers, a disorganized sarcomeric structure, incr

51 Extraocular muscles contain two types of muscle fibers according to their innervation pattern: si

52 ns initially converge onto each postsynaptic muscle fiber, all redundant inputs are removed during ea

53 Comparative muscle fiber analysis showed that, the type I muscle fib

54 uscle is a heterogeneous tissue comprised of muscle fiber and mononuclear cell types that, in additio

55 d restoration in the architecture of cardiac muscle fibers and a reduction in the extent of fibrosis

56 aling of nuclei in multinucleated Drosophila muscle fibers and identify global and local cellular inp

57 itive and negative strains are considered in muscle fibers and in nonmuscle intracellular cargo trans

58 scues the Ca(2+) release defects in isolated muscle fibers and increases the lifespan and mobility of

59 , and coursed in apposition with, bundles of muscle fibers and interstitial cells of Cajal.

60 performed by many other groups using single muscle fibers and isolated myofibrils.

61 reconcile previous contradictory reports in muscle fibers and isolated RyRs, where Mg(2+) is present

62 Additionally, fungal cells invaded host muscle fibers and joined together to form networks that

63 ng of mAgrin to hypoglycosylated alpha-DG on muscle fibers and possibly abrogation of binding from mo

64 but an increase in lean mass and glycolytic muscle fibers and reduced fat mass.

65 ments reflect the function of the underlying muscle fibers and sarcomeres.

66 eurons when changing their target innervated muscle fibers and sensory feedback.

67 using RNA-seq of subtype-pooled single human muscle fibers and single cell RNA-seq of mononuclear cel

68 depends upon interactions between developing muscle fibers and the extracellular matrix (ECM) that an

69 e microimaging techniques to visualize mouse muscle fibers and their nuclei.

70 has been applied to differentiate PSCs into muscle fibers and their progenitors in vitro.

71 Excitability differs among muscle fibers and undergoes continuous changes during de

72 ich is involved in the cellular structure of muscle fibers and, along with DMD, forms part of the dys

73 nied by reduced inflammation, more oxidative muscle fibers, and improved strength of the weak diaphra

74 scle fibers (SIFs), similar to most skeletal muscle fibers, and multiply innervated muscle fibers (MI

75 ced locomotion, reduced diameter of skeletal muscle fibers, and reduced expression of muscle-specific

76 D) is characterized by a progressive loss of muscle fibers, and their substitution by fibrotic and ad

77 netic stimulation-induced muscle relaxation, muscle fiber- and sarcomere-contractility assays, low-an

78 Our findings highlight that avian skeletal muscle fibers are capable of productive influenza virus

79 Specifically, fewer muscle fibers are degenerating, fiber size varies less,

80 We find that muscle fibers are DNA scarce compared to other cells, an

81 art Muscle (muHM) arrays, in which elongated muscle fibers are formed in an easily fabricated templat

82 hogonally oriented endodermal and ectodermal muscle fibers are jointly activated during longitudinal

83 Transport distances in skeletal muscle fibers are mitigated by these cells having multip

84 It is, however, unclear whether target muscle fibers are more than naive substrates in this pro

85 Muscle fibers are the largest cells in the body, and one

86 neuromuscular junction pathology, increased muscle fiber area, and extended survival.

87 Studies on isolated cells and muscle fibers as well as intact animals have shown that

88 es insights into the contractile strength of muscle fibers as well as the length of the thin filament

89 he low skeletal muscle index and significant muscle fiber atrophy (P < 0.0001) in patients with cache

90 n vitro, anti-SRP and anti-HMGCR Abs induced muscle fiber atrophy and increased the transcription of

91 which is both sufficient to induce skeletal muscle fiber atrophy and required for Gadd45a-mediated s

92 tically ill patients have manifest diaphragm muscle fiber atrophy and weakness in the absence of mito

93 s treatment failed to rescue the age-related muscle fiber atrophy associated with muscle atrophy and

94 Skeletal muscle fiber atrophy develops in response to severe seps

95 redox environment is not a key regulator of muscle fiber atrophy during sarcopenia but may play a ke

96 resulted in reduced contractile function and muscle fiber atrophy for longer duration of MV.

97 Sepsis triggers more severe and sustained muscle fiber atrophy in limb muscles when compared with

98 In addition, the muscle fiber atrophy was associated with high levels of

99 Skeletal muscle fiber atrophy was induced (P < 0.05) by 22% in MC

100 n mouse models of cancer cachexia, including muscle fiber atrophy, sarcolemmal fragility, and impaire

101 y and required for Gadd45a-mediated skeletal muscle fiber atrophy.

102 ich is necessary and sufficient for skeletal muscle fiber atrophy.

103 however, at the time that the denervation of muscle fibers begins at about P50, resulting in a state

104 d functional analysis, we investigated adult muscle fiber bioenergetics in this mouse model.

105 s of our MyoRobot 2.0 for facilitated single muscle fiber biomechanics assessment.

106 impair its ability to polymerize within the muscle fiber BM.

107 -1 reduced inflammatory cell infiltration of muscle fibers, but only early in disease progression.

108 ockout or knockdown increased innervation of muscle fibers by dorsal root ganglion neurons.

109 uggested a diagnosis of IOM were splaying of muscle fibers by inflammatory infiltrates (n = 9) and mi

110 y the presence of two distinct categories of muscle fibers called type I "red" slow twitch and type I

111 rf2-null mice displayed smaller, immature TA muscle fibers compared with WT counterparts on d 15 afte

112 b)orders, possibly due to specializations in muscle fiber composition and musculoskeletal systems.

113 r injury and analyzed using a combination of muscle fiber contractility assessments, RNA sequencing,

114 Muscle samples were used to measure single-muscle fiber contractility.

115 solution can predict the characteristics of muscle fiber contraction, including duty ratio, shorteni

116 elation between NOX4 expression and skeletal muscle fiber cross-sectional area in pancreatic cancer p

117 ive correlation between SIRT1 expression and muscle fiber cross-sectional area in pancreatic cancer p

118 29, and 51% with corresponding reductions in muscle fiber cross-sectional area of 18, 42, and 69% aft

119 d KI/KO mice both have significantly smaller muscle fiber cross-sectional area.

120 that fld mice exhibited smaller regenerated muscle fiber cross-sectional areas compared with wild-ty

121 Two-dimensional (2D) human skeletal muscle fiber cultures are ill-equipped to support the co

122 ult from a defect in the linkage between the muscle fiber cytoskeleton and the basement membrane (BM)

123 Defects in this BM lead to muscle fiber damage from the force of contraction.

124 tor muscle neovascularization, and decreased muscle fiber damage.

125 rotected them from both cardiac and skeletal muscle fiber damage.

126 levels of the protein eventually resulted in muscle fiber defects, neuromuscular junction abnormaliti

127 Muscle fiber degeneration or regeneration was evident in

128 n, fatty replacement of skeletal muscle, and muscle fiber degeneration.

129 d intestinal motilities along with thickened muscle fibers, demonstrating a critical role of mst in t

130 ) have disorganized microtubules whereas mdx muscle fibers depleted of tubb6 (but not of tubb5) norma

131 rnal-zygotic tmem2 mutants (MZtmem2) exhibit muscle fiber detachment, in association with impaired la

132 tem cell proliferation to differentiation to muscle fiber development, are each controlled by fate-de

133 Leg muscle fiber diameter remained subnormal at 14 days with

134 rrelated with increases in muscle weight and muscle fiber diameter, resulting in long-term improvemen

135 al muscle dysfunction as by judged decreased muscle fiber diameter.

136 e expression that promotes normal intrafusal muscle fiber differentiation and fusimotor innervation h

137 Furthermore, the post-synaptic muscle fibers displayed increased distinct clusters of a

138 displayed a typical pattern of slow and fast muscle fiber distribution, and regained normal slow musc

139 more, when co-cultured with human intrafusal muscle fibers, DRG organoid sensory neurons contact thei

140 s characterized by a non-recoverable loss of muscle fibers due to ablative surgery or severe orthopae

141 designed to simulate the in vivo dynamics of muscle fibers during swimming.

142 n important role in fuel delivery in Mb-rich muscle fibers (e.g. type I fibers and cardiomyocytes), a

143 ile forces and cytosolic calcium dynamics of muscle fibers embedded in three-dimensional biopolymer g

144 n which proliferative muscle progenitors and muscle fibers establish the skeletal musculature.

145 Surprisingly, a few muscle fibers express strong F-alpha-DG.

146 Multinucleated skeletal muscle fibers form through the fusion of myoblasts durin

147 r posttranscriptional regulator HuR promotes muscle fiber formation in cultured muscle cells.

148 HuR switches its function from a promoter of muscle fiber formation to become an inducer of muscle lo

149 s a biomarker of the quantity and quality of muscle fiber formation.

150 avy chain 1 (Smyhc1), are the first group of muscle fibers formed during myogenesis.

151 well as the length of the thin filaments, in muscle fibers from 51 patients with thin filament myopat

152 Diaphragm muscle fibers from critically ill patients displayed sig

153 Permeabilized muscle fibers from HFD-fed SIRT3 knockout (KO) mice show

154 Muscle fibers from MTM1-deficient mice present defects i

155 Lower force generation was observed in muscle fibers from patients of all genotypes.

156 ic ablation of BDNF shifts the proportion of muscle fibers from type IIB to IIX, concomitant with ele

157 tem cells within their endogenous niche, and muscle fiber fusion at single-cell resolution.

158 by forming a complex with MEKK4 in skeletal muscle fibers, Gadd45a increases MEKK4 protein kinase ac

159 lyze nuclear scaling in whole multinucleated muscle fibers, genetically manipulate individual compone

160 llular matrix remnants from injured skeletal muscle fibers, "ghost fibers," govern muscle stem/progen

161 pression profile properties in fast and slow muscle fibers had been investigated at the mRNA levels,

162 Cultured Fnip1-null muscle fibers had higher oxidative capacity, and isolate

163 Synaptic pathology and denervation of target muscle fibers has been reported prior to the appearance

164 owever, the subcellular location for SOCE in muscle fibers has not been unequivocally identified.

165 matergic motor neurons synapsing on the same muscle fiber in Drosophila larvae.

166 We hypothesized that weakness of diaphragm muscle fibers in critically ill patients is accompanied

167 e exploration of both correct and off-target muscle fibers in Drosophila embryos.

168 We observed that regenerating and necrotic muscle fibers in muscle biopsy samples from DMD patients

169 soleus) and fast (extensor digitorum longus) muscle fibers in situ and determined cellular dimensions

170 skinned guinea pig (Cavia porcellus) cardiac muscle fibers in the absence and presence of 0.3 and 3.0

171 velopment, a process requiring maturation of muscle fibers in the presence of motor neuron endplates.

172 of ATF4 (the bZIP domain) in mouse skeletal muscle fibers in vivo Interestingly, we found that ATF4

173 d45a as it induces atrophy in mouse skeletal muscle fibers in vivo We found that Gadd45a interacts wi

174 interacts with multiple proteins in skeletal muscle fibers, including, most prominently, MEKK4, a mit

175 trate multiple degenerating and regenerating muscle fibers, increased central nuclei, elevated creati

176 Normally quiescent, following muscle fiber injury, we show that these cells express Zf

177 the activity of individual motor units (the muscle fibers innervated by a single motor neuron) and m

178 In normal adult muscle, each muscle fiber is innervated by a single axon, but at birt

179 At birth, each mammalian skeletal muscle fiber is innervated by multiple motor neurons, bu

180 nectivity between motor neuron endplates and muscle fibers is confirmed with calcium imaging and elec

181 Dye influx into muscle fibers lacking both dysferlin and the related pro

182 Muscle fiber length is nearly uniform within a muscle bu

183 maging of FOXO1-GFP in adult isolated living muscle fibers maintained in culture to explore the effec

184 We find that Wnt4 produced by the muscle fiber maintains SC quiescence through RhoA.

185 ise tolerance, mitochondrial biogenesis, and muscle fiber maintenance in miR-133a-deficient mice.

186 In healthy adult skeletal muscle fibers microtubules form a three-dimensional grid

187 bers (SIF) and multiply innervated nontwitch muscle fibers (MIF).

188 letal muscle fibers, and multiply innervated muscle fibers (MIFs).

189 In skeletal muscle fibers, mitochondria are densely packed adjacent

190 een HuR and miR-330 as a mechanism via which muscle fibers modulate, in part, STAT3 expression to det

191 Changes in muscle fiber morphology and mitochondrial respiratory fu

192 P5K orthologs in zebrafish embryos disrupted muscle fiber morphology and resulted in abnormal eye dev

193 e exosomes, it is not known whether skeletal muscle fibers (myofibers) release exosomes.

194 es exhibited a chronic myopathy with ongoing muscle fiber necrosis and regeneration and accumulation

195 -atrophic gene transcription when present in muscle fiber nuclei.

196 Our results indicate that avian skeletal muscle fibers of chicken and duck could be significant c

197 These findings show that diaphragm muscle fibers of critically ill patients display atrophy

198 Both slow- and fast-twitch diaphragm muscle fibers of critically ill patients had approximate

199 iber size and increased fibrosis in skeletal muscle fibers of D2-mdx mice compared with B10-mdx and c

200 We hypothesized that diaphragm muscle fibers of mechanically ventilated critically ill

201 croscopy confirmed shorter thin filaments in muscle fibers of these patients.

202 OY phytoplasmas spread along the actin-based muscle fibers of visceral muscles and accumulated on the

203 d myogenic cells then fuse to repair damaged muscle fibers or form new muscle fibers.

204 ure, when they remain associated with single muscle fibers, or when they reside in muscle biopsies.

205 e clamp method can better maintain diaphragm muscle fiber orientation but is used less often because

206 on filopodia repeatedly contacted off-target muscle fibers over several hours during late embryogenes

207 Wild-type muscle fibers overexpressing green fluorescent protein (

208 ncreased oxidative capacity in permeabilized muscle fibers (P-time x treatment < 0.05, P-EGCG+RES < 0

209 dipocytes treated with mirabegron stimulated muscle fiber PGC1A expression in vitro (P < 0.001).CONCL

210 rcopenia and prevented age-related change in muscle fiber phenotype.

211 dings reveal that myonuclei within syncytial muscle fibers possess distinct transcriptional profiles

212 Importantly, in skinned muscle fiber preparations, we found markedly impaired le

213 YAP forced-activity in muscle fibers prevents the decrease of JAG2 expression a

214 ts showed that msLam-111 treatment increased muscle fiber regeneration and repair with improved muscl

215 rescues macrophage homeostasis and skeletal muscle fiber regeneration, showing that Tregs can direct

216 nown as terminal sprouting, is key to normal muscle fiber reinnervation following nerve injury and it

217 These findings demonstrate that skeletal muscle fibers release exosomes which can exert biologica

218 t E12.5, a time when phrenic nerves approach muscle fibers, resulted in smaller and fewer nerve-induc

219 el, large ice crystals are formed outside of muscle fibers resulting in transversal shrinkage.

220 We show that muscle fibers secrete and concentrate the fibroblast gro

221 Here, we show that muscle fibers secrete and concentrate the fibroblast gro

222 igh-threshold MNs innervating fast fatigable muscle fibers selectively degenerate compared with low-t

223 tra of BSL-myosin bound to actin in oriented muscle fibers showed sharp three-line spectra, indicatin

224 lar muscles contain singly innervated twitch muscle fibers (SIF) and multiply innervated nontwitch mu

225 their innervation pattern: singly innervated muscle fibers (SIFs), similar to most skeletal muscle fi

226 in a significant decrease in both diaphragm muscle fiber size and diaphragm-specific force productio

227 re, repletion of vitamin D improved skeletal muscle fiber size and in vivo muscle function, normalize

228 of the gastrocnemius, revealing a decreased muscle fiber size and increased fibrosis in skeletal mus

229 lts, muscle regeneration was stimulated, and muscle fiber size decreased markedly.

230 (1-7)/MasR activation did not affect healthy muscle fiber size in vitro or in vivo but attenuated atr

231 and muscle atrophy and maintains individual muscle fiber size while decreasing oxidative damage.

232 he motor neurons of SMA model mice increases muscle fiber size, enhances the post-synaptic NMJ area,

233 ads to neonatal and postnatal alterations in muscle fiber size, fiber number, fiber type and misregul

234 aging mouse skeletal muscle, while genetic, muscle fiber-specific activation of mTORC1 is sufficient

235 epends on the configuration of the adjoining muscle fiber 'spokes'.

236 Inhibition of NOTCH ligand activity in muscle fibers suffices to reduce the progenitor pool.

237 owever, centrally aligned nuclei observed in muscle fibers suggest for muscle regeneration in these s

238 on membrane repair is abolished in mg53(-/-) muscle fibers, suggesting that MG53 functions as a poten

239 proper nuclear position is not restricted to muscle fibers, suggesting that the nesprin-dependent rec

240 scle force and intracellular organization of muscle fibers, supporting BIN1 as a negative regulator o

241 side-VI is expressed in muscle fibers targeted by the ISNb nerve, as well as at

242 Lightweight artificial muscle fibers that can match the large tensile stroke of

243 apse formed between motoneurons and skeletal muscle fibers that is covered by Schwann cells (SCs).

244 We also engineered muscle fibers that mimic the native myofiber of the MuSC

245 sed of anatomically segregated fast and slow muscle fibers that possess different metabolic and contr

246 Within skeletal muscle fibers, the ATF4-C/EBPbeta heterodimer interacts

247 used as a model system because of its large muscle fibers, there are two troponin-C isoforms, called

248 ce thick-to-thin filament spacing in skinned muscle fibers, thereby increasing force production at lo

249 Spinal motor neurons and the peripheral muscle fibers they innervate form discrete motor units t

250 differentiation, and ultimately formation of muscle fibers through targeted, staged mRNA decay.

251 e that transmits signals from motoneurons to muscle fibers to control muscle contraction.

252 s body umbrella shape, causing radial smooth muscle fibers to converge around 'hubs' which serve as p

253 n remodeling are sufficient for predisposing muscle fibers to form ring fibers.

254 TEV protease, and find that the response of muscle fibers to length changes requires mechanical tran

255 g is associated with an increased ability of muscle fibers to maintain cytosolic redox homeostasis in

256 This allowed muscle fibers to operate at a shorter sarcomere length a

257 le where it physically links the interior of muscle fibers to the extracellular matrix.

258 fficiently produce striated, millimeter-long muscle fibers together with satellite-like cells from hu

259 IMP2-deficient muscle fibers treated with a mitochondrial uncoupler to

260 ct many of the major characteristics of each muscle fiber type and raises the question of what sequen

261 imulated leg blood flow and a more oxidative muscle fiber type distribution.

262 Mb) are reduced when controlling for tissue/muscle fiber type or latent factors.

263 that controlling for heterogeneity in tissue/muscle fiber type reduces the number of physiological tr

264 esults indicate that Fnip1 controls skeletal muscle fiber type specification and warrant further stud

265 s that under normal conditions HuR modulates muscle fiber type specification by promoting the formati

266 sm, intramuscular fatty acid deposition, and muscle fiber type which attribute to pork quality (TG, F

267 coordinates the exercise-stimulated skeletal muscle fiber-type switch from glycolytic fast-twitch (ty

268 the development and performance of different muscle fiber types in Chinese perch.

269 ey characteristics of the different striated muscle fiber types, including maximum shortening velocit

270 We report that individual mdx muscle fibers undergo progressive hypertrophy that conti

271 ally greater than control or individual null muscle fibers, underscoring the importance of shoulder-l

272 referential diffusion of water along cardiac muscle fibers using diffusion tensor cardiac magnetic re

273 e" units, which innervate deeper fast-twitch muscle fibers via medial nerves.

274 which exclusively innervate superficial slow muscle fibers via septal nerves.

275 physiology, and dynamic imaging of zebrafish muscle fibers, we find significantly reduced DHPR levels

276 d 2 (ERK1/2) in slow-twitch, type 1 skeletal muscle fibers, we studied the soleus muscle in mice gene

277 cle activation and fiber work done while the muscle fibers were lengthening compared to rearfoot stri

278 energy storage and fiber work done while the muscle fibers were shortening compared to rearfoot strik

279 axonal dieback occurs first from fast-twitch muscle fibers, whereas slow-twitch fibers remain innerva

280 is poorly understood, especially in skeletal muscle fibers, which are among the largest cells, contai

281 ucleated and contractile structures known as muscle fibers, which arise from the fusion of myoblasts

282 esults in a decreased calcium sensitivity of muscle fibers, which could in turn plays a role in muscl

283 tion, where YAP activates JAG2 expression in muscle fibers, which in turn regulates the pool of fetal

284 ated respiration was higher in permeabilized muscle fibers, which may contribute to the increased rel

285 enabling the 3D reconstruction of individual muscle fibers, which was previously impossible using any

286 proportion of type IIa fast-twitch oxidative muscle fibers, which was verified using immunofluorescen

287 is characterized pathologically by necrotic muscle fibers with absent or minimal inflammation.

288 antibodies targeting TRIM72 lead to skeletal muscle fibers with compromised membrane barrier function

289 ches for restoration of F-alpha-DG in mature muscle fibers with defects in FKRP functions.

290 ion of GFP-JPH1 deletion mutants in skeletal muscle fibers with in vitro biochemical experiments, we

291 ed numerous nitric oxide synthase 2-positive muscle fibers with sarcoplasmic colocalization of marker

292 reased axial mechanical compliance in single muscle fibers with Young's moduli between 40 - 60 kPa wa

293 heterogeneous within myotubularin-deficient muscle fibers, with focally defective areas recapitulati

294 rosis (n = 8) in the endomysium or replacing muscle fibers, with no granulomas or vasculitis.

295 between the vasculature, neural network, and muscle fiber within the muscle stem cell niche.

296 or fate, we embedded isolated SC-associated muscle fibers within biochemically inert agarose gels tu

297 d oxidation in both glycolytic and oxidative muscle fibers without altering mitochondrial copy number

298 les had significant numbers of smaller-sized muscle fibers, without signs of regeneration.

299 esis that muscles rich in type I vs. type II muscle fibers would exhibit similar changes in intramyoc

300 ass, due to fewer and/or smaller constituent muscle fibers, would exacerbate the impact of muscle los