ライフサイエンスコーパス: mutagenize

1 catalytic activity, which were subsequently mutagenized.

2 erved residues among 24 identified CPDs were mutagenized.

3 ble for essentially any organism that can be mutagenized.

4 ion of the B. subtilis citB gene product was mutagenized.

5 deaminase residues in each PPR protein were mutagenized.

6 We mutagenized 19 regulatory elements that drive coexpressi

7 We mutagenized 33 amino acids with surface-exposed side cha

8 function on a large scale, we predicted and mutagenized 455 binding sites in human promoters.

9 in by unnatural amino acid misincorporation, mutagenize a universal pY-binding Ab to create a first b

10 We chemically mutagenized a cikA-null S. elongatus strain and screened

11 We mutagenized a conserved CCTSE metal-binding motif in the

12 me-associated matrix protein degradation, we mutagenized a line expressing GFP-ICL, which is degraded

13 We mutagenized a non-metastatic mouse cancer cell line usin

14 ack inhibition properties of GK, we randomly mutagenized a plasmid carrying tomato tomPRO1 cDNA, whic

15 As proof of concept, we mutagenized a selected region within the leukemic oncoge

16 We mutagenized A. actinomycetemcomitans clinical strain CU1

17 ed on the basis of mutant phenotypes from FN-mutagenized A. thaliana populations.

18 signaling and nuclear gene activation after mutagenizing a flu line expressing the luciferase report

19 were plaque purified from a pool of randomly mutagenized Ad5 that was repeatedly passaged in the huma

20 transactivation potential of a large set of mutagenized ADs.

21 due in the RING domain is altered in our EMS-mutagenized allele of nopo, suggesting that E3 ligase ac

22 These four positions were mutagenized alone and in various combinations in both HP

23 The program operates by mutagenizing an input nucleic acid sequence according to

24 We also report the first 6144 mutagenized and archived F1's predicted to carry up to 3

25 This line was mutagenized and M(2) seedlings screened for constitutive

26 rative whole-genome sequencing of chemically mutagenized and natural Pgt isolates to identify a funga

27 mprising this pathway, a Deltahtx strain was mutagenized and one mutant lacking the ability to grow o

28 n, a DNA segment encoding these proteins was mutagenized and placed into B. subtilis to create a mero

29 AgrB and AgrD function, the agrBD genes were mutagenized and screened for deficiencies in AIP product

30 2 single-chain TCR (Vbeta-linker-Valpha) was mutagenized and selected for thermal stability and surfa

31 lysis-sensor 1 and sensor 2-were identified, mutagenized and used to validate predictions of this mod

32 sp. strain PCC 7120 have been identified by mutagenizing and screening for mutants that require fixe

33 pt3 was amplified from F62DeltaLgtA, cloned, mutagenized, and inserted into the chromosome of N. gono

34 rter lines were ethyl methanesulfonate (EMS) mutagenized, and stable M(2) seedlings were screened for

35 This enriched population is then mutagenized, and successive rounds of random mutagenesis

36 e malaria parasite Plasmodium falciparum was mutagenized, and tests were carried out in Escherichia c

37 d Asp(39)) clusters in pro-Crp4-(20-92) were mutagenized, and variants were assayed for differential

38 By screening N-ethyl-N-nitrosourea-mutagenized animals for alterations in rhythms of wheel-

39 cytoskeleton in otherwise apparently normal mutagenized animals.

40 SB transposition can easily be controlled to mutagenize any target tissue and can therefore, in princ

41 ction, SB transposition can be controlled to mutagenize any target tissue and thus potentially induce

42 t for a population of ethyl methanesulfonate-mutagenized Arabidopsis (Arabidopsis thaliana).

43 acid content in the seeds of 10,000 randomly mutagenized Arabidopsis lines, and 322 Arabidopsis lines

44 The method is exemplified by a screen of mutagenized Arabidopsis plants subjected to growth in li

45 A screen of ethylmethanesulfonate-mutagenized Arabidopsis seedlings recovered seven lines

46 An HPLC-based screen of 5500 mutagenized Arabidopsis thaliana lines produced 33 gluco

47 estigate silencing mechanisms, we screened a mutagenized Arabidopsis thaliana population for expressi

48 its ability to acquire its Fe-S cluster when mutagenized at the identified site of interaction with I

49 d 6275 Drosophila strains bearing homozygous mutagenized autosomes (obtained from C. Zuker) for hyper

50 Screening of a library of transposon-mutagenized B. anthracis spores identified a mutant disp

51 er inserts was made more efficient by wobble-mutagenizing both the inner repeat and the exogenous ins

52 Here we report ebs2 (EMS-mutagenized bri1 suppressor 2) as an allele-specific sup

53 t a missense mutation in the Arabidopsis EMS-mutagenized bri1 suppressor 3 (EBS3) gene suppresses a d

54 BRI1, resulted in identification of the EMS-mutagenized bri1 suppressor 5 (EBS5) gene that encodes a

55 OS9 in a recently discovered ERAD mutant ems-mutagenized bri1 suppressor 6 (ebs6-1).

56 ER membrane and associate with Hrd1 via EMS-mutagenized Bri1 Suppressor7 (EBS7), a plant-specific co

57 ated 6400 pedigreed M4 mutant pools from EMS-mutagenized BTx623 seeds through single-seed descent.

58 somal locus (liguless-1 being the first one) mutagenized by a re-designed I-CreI-based endonuclease,

59 , a DeltapilA strain (T4P(-) and EPS(-)) was mutagenized by a transposon and screened for EPS(+) muta

60 interaction with this inhibitor, we randomly mutagenized by error-prone PCR the E. coli dsbB gene and

61 Seeds of a P6-transgenic line, A7, were mutagenized by gamma-irradiation and M2 seedlings were s

62 found that certain cancers were excessively mutagenized by human-specific L1s, while no verifiable i

63 the 5' end of the chromosomal fliC gene was mutagenized by PCR-directed mutagenesis.

64 These hammerhead ribozymes site-specifically mutagenized by selenium reveal the close relationship be

65 Thus, we screened a population of mutagenized C. trachomatis strains for mutants that fail

66 Complementation with wild-type, but not mutagenized, C1qbp restored OXPHOS protein levels and mi

67 We randomly mutagenized C53 and C37 and isolated many C37 mutants wi

68 ARCH DESIGN AND Offspring of ethylnitrosurea-mutagenized C57BL/6 mice were bred to homozygosity, main

69 phy, we ultrasound scanned 87,355 chemically mutagenized C57BL/6J fetal mice and recovered 218 CHD mo

70 observed in an ethyl methanesulfonate (EMS)-mutagenized Caenorhabditis elegans strain.

71 We have created a library of 2007 mutagenized Caenorhabditis elegans strains, each sequenc

72 genomes, such as those of premutagenized and mutagenized Caenorhabditis elegans strains.

73 d oligonucleotide libraries and selected the mutagenized cells for erythromycin-resistant mutants.

74 In this study, we used libraries of randomly mutagenized cells to discover cellular genes that are es

75 Mutagenized cells were first selected for resistance to

76 n of restriction enzyme-mediated integration mutagenized cells yielded numerous mutants with the desi

77 Ten pools of chemically mutagenized Chinese hamster ovary (CHO-K1) cells were ch

78 ies whose eyes are entirely homozygous for a mutagenized chromosome arm.

79 or are now fixed for lethal mutations on the mutagenized chromosome.

80 conducted a forward genetic screen of >4000 mutagenized chromosomes bearing lethal mutations that af

81 rategy in which ethylmethane sulfonate (EMS) mutagenized chromosomes were maintained as heterozygotes

82 4304-insensitive mutant (rim) screen using a mutagenized chs3-2D population.

83 gene, and 5'-splice site) typically produced mutagenized clones in which vector sequences spliced to

84 icial quasispecies consisting of 48 randomly mutagenized clones.

85 In this study, we screened 5000 randomly mutagenized colonies for defects in S-motility and EPS a

86 mepA-overexpressing clinical strains, and to mutagenize conserved acidic residues.

87 on mutagenesis of an ordered cosmid library; mutagenized cosmids with fully characterized insertions

88 However, mutagenized cultured cells require cloning to yield homo

89 d the structure and function of Zta, we have mutagenized cysteine residues within or adjacent to the

90 We mutagenized D44 and R45 to alanine as these mutations ar

91 ion-independent oligomerization, we randomly mutagenized DNA coding for an NtrC without its central d

92 exchanged with an incoming plasmid bearing a mutagenized dnaA gene.

93 e determined that SN1-type agents preferably mutagenize double-stranded DNA (dsDNA), and the mutation

94 We mutagenized each of the six glycine residues (at positio

95 Conversely, mutagenizing either the bovine PSI domain, P33L, or the

96 ith MS2-modified sgRNAs, we can specifically mutagenize endogenous targets with limited off-target da

97 of plasmids containing the wild-type and the mutagenized endonuclease gene; (3) back-crosses with the

98 ide ABPs identifies the acid/base residue in mutagenized enzyme, as only the beta-aziridine ABP can b

99 By interrogating both the mutagenized epithelium and its microenvironment, we surm

100 istence, we selected a library of transposon-mutagenized Escherichia coli cells for survival to multi

101 fied Himar1 transposon (HimarFT) was used to mutagenize F. tularensis LVS.

102 derived from an individual ethyl-nitrosurea mutagenized F(0) fish, two showed increased or decreased

103 ENU-mutagenized F5(L/L) males and F5(L/+)Tfpi(+/-) females w

104 trasound scanned 7546 mouse fetuses from 262 mutagenized families, and identified 124 families with c

105 We mutagenized ferritin's three-fold pores (3FPs), i.e. the

106 Mutagenized fish lines are being made freely available t

107 ucted a forward genetic screen of chemically mutagenized flies to identify short-sleeping mutants and

108 From a screen of 42,500 mutagenized flies, 32 mutations on chromosome 3R that co

109 in a screen of ethyl methanesulfonate (EMS) mutagenized flu ex1 plants for suppressor mutants with a

110 th the transient expression of wild-type and mutagenized forms of the LC correlated with the cytopath

111 Second, we generated a mutagenized frozen library to permit the isolation of ta

112 We used PCR to randomly mutagenize ftsI, ligated the products into a green fluor

113 Screening of fungal virulence traits using mutagenized fungi to determine changes in fungal infecti

114 equencing and mapping technologies to widely mutagenize genes in the zebrafish genome.

115 ed in conjunction with transposon vectors to mutagenize genes, and highlight versatile experimental s

116 We screened approximately 7000 EMS-mutagenized genomes and isolated and mapped seven indepe

117 the genome-wide mutational profile of 17 EMS-mutagenized genomes as assessed with a bioinformatic pip

118 ng of cutaneous malignancies reveals heavily mutagenized genomes with large numbers of low-prevalence

119 Here, from a screen of 150,000 mutagenized genomes, we isolated four C. elegans mutants

120 rossing the mutant with a wild-type (WT; non-mutagenized) genotype, and F2 segregants displaying the

121 We mutagenize GFP and select for spectrum-shifted variants,

122 tant mice derived from N-ethyl-N-nitrosourea-mutagenized grandsires for intestinal homeostasis abnorm

123 tal diploid males in the F1 progeny of X-ray mutagenized haploid males.

124 natural transformation with chromosomal DNA mutagenized heavily by in vitro transposition.

125 To better understand this step, we mutagenized hgbA by deletion of each of the 11 putative

126 og for the MMR gene MutS Homolog 2 (Msh2) by mutagenizing, identifying, and cataloging 26 deleterious

127 nd class 3 flagellar promoters were randomly mutagenized in Salmonella.

128 Fourteen of the 29 amino acids were mutagenized in the maize endosperm large subunit (SHRUNK

129 as identified from an ethyl methanesulfonate-mutagenized indica cultivar IR68 population and was prev

130 point mutations in populations of chemically mutagenized individuals.

131 iochemical analyses due to the difficulty in mutagenizing infectious isolates of B. burgdorferi.

132 , we propose that a TR reverse transcript is mutagenized, integrated into VR as a single non-coding s

133 d has been used for TILLING extensively, and mutagenized it with 50 mm ethylmethane sulfonate.

134 stream form cell lines that express randomly mutagenized KREPB5 alleles.

135 Somatic rearrangements contribute to the mutagenized landscape of cancer genomes.

136 Using HiTS-RAP, we measured the affinity of mutagenized libraries of GFP-binding and NELF-E-binding

137 KAT1 pore domain, we have screened randomly mutagenized libraries of S4 or S1-S3 for second-site sup

138 A high-density transposon mutagenized library was challenged with a panel of antib

139 ideal to have a stable collection of heavily mutagenized lines that can be screened over an extended

140 election method for the generation of stable mutagenized lines with a high concentration of total and

141 iovascular defects in 79 pups from 47 of 321 mutagenized lines.

142 Finally, using a hyperactive AID variant, we mutagenize loci both upstream and downstream of transcri

143 homologous recombination-driven shuffling of mutagenized loops.

144 entification of eight ethyl methanesulfonate-mutagenized loss-of-function bin2 alleles and one T-DNA

145 Populations of EMS-mutagenized M(2) seedlings were sprayed with twice the 1

146 by screening colonies of transposon (Tn611)-mutagenized M. smegmatis.

147 esin facilitates these diverse processes, we mutagenized Mcd1p, the kleisin regulatory subunit of bud

148 Here, we report that mutagenizing MELK with CRISPR/Cas9 has no effect on the

149 Mutagenizing Met-915 or Met-956 selectively abolishes ac

150 We screened mutagenized mice and observed a neonatal lethal skeletal

151 tified a line of N-ethyl-N-nitrosourea (ENU) mutagenized mice demonstrating retinal patches.

152 Apc(Min) SB-mutagenized mice developed three times as many polyps as

153 The screening of more than 5000 mutagenized mice established two obese pedigrees in whic

154 hese studies were performed using chemically mutagenized mice expected to be enriched for birth defec

155 is to create random mutations and screen the mutagenized mice for their behavioral phenotypes.

156 sease-causing mutations can be identified in mutagenized mice has been markedly increased by recent a

157 etic screen with N-ethyl-N-nitrosourea (ENU)-mutagenized mice linked IRF2 to inflammasome signaling.

158 ward genetic screen with ethyl-N-nitrosourea-mutagenized mice links Gsdmd to the intracellular lipopo

159 osourea mutagenesis to generate pedigrees of mutagenized mice that were subject to recurrent screens

160 We used a genome-wide screen in mutagenized mice to identify genes which inactivation pr

161 a behavioral screen of N-ethyl-N-nitrosourea mutagenized mice we identified a mutant line which we na

162 d from the breeding of N-ethyl-N-nitrosourea mutagenized mice were formalin-fixed and stained with io

163 Ethylnitrosourea mutagenized mice were ultrasound-interrogated by fetal e

164 tify, from a screen of N-ethyl-N-nitrosourea-mutagenized mice, a mutation causing both profound susce

165 , identified from N-ethyl-N-nitrosurea (ENU)-mutagenized mice, develops a dominant lamellar cataract.

166 gram/electromyogram-based screen of randomly mutagenized mice.

167 icient memory (DM)) of N-ethyl-N-nitrosourea mutagenized mice.

168 Mutagenized MLH1 fragments of the human coding region we

169 utagenesis was used to create 5 libraries of mutagenized MNV infectious clones, each containing a 15-

170 y ultrasound to screen N-ethyl-N-nitrosourea mutagenized mouse fetuses for congenital cardiovascular

171 An ENU-mutagenized mouse line (R3), displaying attenuated retin

172 n parallel, characterization of a chemically mutagenized mouse line that displays features similar to

173 Here, we report two chemically mutagenized mouse models carrying point mutations in Rho

174 0 I325N, from an N-ethyl-N-nitrosourea (ENU)-mutagenized mouse strain.

175 and Ca(2+)/Ca(2+) exchange by wild-type and mutagenized NCX_Mj confirm that transport of both Na(+)

176 dine deaminase (nCas9-Target-AID) systems to mutagenize Nicotiana tabacum protoplasts and to regenera

177 Bcl-2 carrying a mutagenized, non-toxic BH3 domain fails to support mutan

178 Transient transfection of mutagenized NOTCH1 missense constructs also revealed sig

179 unique transposon mutagenesis strategy that mutagenizes NSCs in culture, followed by additional roun

180 From a mutagenized oat population, produced by ethyl methanesul

181 Using a mutagenized oat-population we screened 1700 different li

182 Mutagenized OCA2 transgenes stimulate melanin synthesis

183 TILLING searches the genomes of mutagenized organisms for mutations in a chosen gene, ty

184 Mutagenized organisms were expanded in small subpopulati

185 Using mutagenized OSM-9 expressed in the head nociceptor neuro

186 ough screening large populations of randomly mutagenized plants.

187 ids and whole-plasmid PCR is used to produce mutagenized plasmid amplicons flanked by loxP.

188 A pool of mutagenized plasmids was transformed into an Escherichia

189 A suppressor screen of mutagenized pmr5 seed selecting for increased powdery mi

190 We analyzed over 1,100 transposon-mutagenized pools of Ba/F3 cells, an IL3-dependent pro-B

191 was identified in an ethyl methanesulfonate-mutagenized population derived from the maize inbred lin

192 cadt1, from an ethyl methanesulphonate (EMS)-mutagenized population of a widely grown Indica cultivar

193 A fast neutron-mutagenized population of Arabidopsis (Arabidopsis thali

194 From an activation-tagged mutagenized population of Arabidopsis plants, we isolate

195 he inserts from individual plants in a T-DNA-mutagenized population of Arabidopsis thaliana, and are

196 expression of its siderophore, we screened a mutagenized population of L. pneumophila for strains tha

197 ction, we screened an ethyl methanesulfonate mutagenized population of Lotus japonicus for mutants de

198 Escherichia coli colonies expressing a mutagenized population of LOV2 derived from Avena sativa

199 tasis, we screened an ethyl methanesulfonate-mutagenized population of nramp3nramp4 seedlings for mut

200 ING, M2 seeds are collected in bulk from the mutagenized population of plants, greatly reducing the l

201 ew mutant, sad2-1, was isolated from a T-DNA mutagenized population of RD29A:LUC plants and shown to

202 A subset of an ethyl methanesulfonate mutagenized population of soybean (Glycine max) 'Forrest

203 ocellulose recalcitrance, we have screened a mutagenized population of the model grass Brachypodium d

204 of the technology, ranging from building the mutagenized population to mutation discovery, and discus

205 An EMS mutagenized population, consisting of approximately 21,2

206 ll] plants sampled from a large fast neutron-mutagenized population.

207 Mutagenized populations have become indispensable resour

208 ay to measure leaf pH to screen fast neutron-mutagenized populations of common ice plant (Mesembryant

209 erated ethyl methanesulfonate- and gamma-ray-mutagenized populations of the C(4) species sorghum (Sor

210 or identifying point mutations in chemically mutagenized populations.

211 avage of the ORF1 polyprotein containing the mutagenized Pro sequence into products identical to thos

212 Luciferase assays on mutagenized promoter constructs followed by electromobil

213 By comparing different truncated and mutagenized promoter constructs, we observed the same mi

214 Test-class animals, homozygous for the ENU-mutagenized proximal Chr 5 and visibly distinguishable f

215 e transiently transfected with wild-type and mutagenized PSA promoter, ARE concatemers and appropriat

216 performed using pseudotype virus expressing mutagenized rabies glycoproteins.

217 ced in the ligand, and a library of randomly mutagenized receptors is screened to identify mutants th

218 We have mutagenized, reconfigured and selectively disrupted indi

219 dentified in a segregating population of EMS-mutagenized red lettuce and characterized biochemically

220 of Cas12a-mediated phytoene desaturase (PDS) mutagenized regenerants, as well as regenerants from wil

221 and sequenced to identify alterations in the mutagenized region.

222 circadian clock from an Arabidopsis thaliana mutagenized reporter line by screening for seedlings wit

223 To distinguish between these mechanisms, we mutagenized residues in the two binding sites and tested

224 iae cytoplasmic dynein as a model system, we mutagenized residues involved in nucleotide binding or h

225 system for biological selection of randomly mutagenized ribulose 1,5-bisphosphate carboxylase/oxygen

226 system for biological selection of randomly mutagenized ribulose-1,5-bisphosphate carboxylase/oxygen

227 By using randomly mutagenized rRNA genes, we mapped rRNA sites where nucle

228 We mutagenized S. aureus strain SH1000 to identify loci ess

229 Visual screening of mutagenized seeds identified a mutant line, designated M

230 th the mouse MHC class I allele H-2K(b) were mutagenized, selected for low surface expression of endo

231 However, mutagenized sequences introduced in trans on episomes or

232 model of the nucleotidyl cyclase domain and mutagenized several residues predicted to be involved in

233 on mice descended from N-ethyl-N-nitrosourea-mutagenized sires.

234 n of G(1) mice born to N-ethyl-N-nitrosourea-mutagenized sires.

235 y interlaced) and amplification of insertion mutagenized sites (AIMS) protocols and is applicable to

236 lume forward genetic screen of insertionally mutagenized somatic cells using a murine leukemia virus

237 A screen of randomly mutagenized SPP2 clones identified an Spp2 protein with

238 F1 preweanling pups from mutagenized Sprague Dawley (SD) male rats were then scre

239 Screens of a randomly mutagenized SpRheb library yielded a mutant, SpRhebD60V,

240 Conversely, SN2-type agents preferably mutagenize ssDNA in yeast.

241 e elucidation of complex rearrangements in a mutagenized strain.

242 Surprisingly, we find that while outcrossing mutagenized strains does reduce the total number of muta

243 Here, we systematically mutagenized structural motifs of PlexB and examined the

244 A mutagenized substrate phage display library based on a 7

245 To further investigate this defect, we mutagenized swoF1 and recovered six partial suppressors

246 One of 21 mutagenized T(0) plants carried two mutated alleles of t

247 Mutagenized TbpAs were expressed on the gonococcal cell

248 ould affect the regulation of P1 by GalR, we mutagenized the -35 element of P1, isolated variants of

249 uence requirements for ZMPSTE24 cleavage, we mutagenized the eight residues flanking the prelamin A s

250 D on the virus life cycle, we systematically mutagenized the entire CT and TMD of NA by converting tw

251 ts important for K+ selectivity, we randomly mutagenized the G protein-coupled inwardly rectifying po

252 We mutagenized the P1 cleavage site Gln(152) into all other

253 Here, we mutagenized the predicted proton donor residues and the

254 To identify these factors, we mutagenized the quadruple clathrin adaptor mutant strain

255 Here, we randomly mutagenized the region encoding residues 14-119 of the P

256 We mutagenized the residue Val-136, which lines the anesthe

257 Here, we first identified and mutagenized the residues at the cleavage and active site

258 We mutagenized the transmembrane domains of a conserved fun

259 To gain insight into this question, we mutagenized the viral genome and sequenced recoverable v

260 By mutagenizing the approximately 17-kDa segment, we also f

261 sidues comprising the RetGC1 binding site by mutagenizing the entire surface of GCAP1 and testing the

262 We show that chemically mutagenizing the genome of cancer cells dramatically inc

263 Mutagenizing the human beta(3) PSI domain to contain the

264 After mutagenizing the predicted extracellular loop of SaeS, w

265 model suggests that nongrowing parent cells mutagenize their own genome and thereby create beneficia

266 n further characterized Leu-30 and Thr-36 by mutagenizing these residues to amino acids with differen

267 further characterized Gly-241 and Gly-400 by mutagenizing these residues to amino acids with varying

268 From 2591 mutagenized third chromosome lines, we identified 33 mut

269 We mutagenized this protein and tested the ability of indiv

270 nonglycosylated protein was expressed after mutagenizing three asparagines (the glycosylation sites)

271 Id1 in which all lysine residues were mutagenized to alanine (lysineless Id1) was also rapidly

272 an beta1-adrenergic receptor (beta1-AR) were mutagenized to characterize their role in signaling by G

273 ining either a GFP or mCherry transgene were mutagenized to create a single nonsense mutation within

274 Each residue was site-specifically mutagenized to evaluate its importance for catalytic act

275 4 residues of the LEDGF/p75 PWWP domain were mutagenized to garner essential details of its function

276 tyrosine (Y) and threonine (T) residues were mutagenized to generate a triple-mutant (Y705 + Y731F +

277 o a gene element, such as a promoter, may be mutagenized to isolate loss-of-function mutants able to

278 OTP84 and CREF7 transgenes were mutagenized to replace the glutamate residue of the HXE

279 ive database of phenotypic information for a mutagenized tomato population, and associated tools such

280 MX2 variants or of variants with an in vitro mutagenized TRX domain induces a constitutive TMX2 polym

281 Engineered RTs were mutagenized using a new, flexible and cost effective met

282 vity observed previously in TCR more broadly mutagenized using in vitro evolution techniques.

283 , which are relatively resistant to DN, were mutagenized using N-ethyl-N-nitrosourea and screened for

284 All 90 putative lysR genes were mutagenized using plasmid insertions as a first step tow

285 ivity was greater when the CRX elements were mutagenized with a 5' to 3' spatial gradient in the nega

286 present study, an E. coli MG1655 strain was mutagenized with a mini-Tn5 Km (kanamycin) transposon, a

287 otor neuron pathfinding in GFP reporter mice mutagenized with ENU.

288 tely, 600,000 worms are grown synchronously, mutagenized with ethyl methane sulfonate, divided in gro

289 om a population of Chinese hamster V79 cells mutagenized with ethyl methane sulfonate.

290 arg1 seeds were mutagenized with ethylmethane sulfonate to identify new

291 harbored up to five mismatches and many were mutagenized with frequencies comparable to (or higher th

292 c sites, DD20 and DD43 on chromosome 4, were mutagenized with frequencies of 59% and 76%, respectivel

293 In step 2, the E156K allele was mutagenized with the objective of increasing enzyme acti

294 spread (small-plaque) phenotype was randomly mutagenized with UV, and 27 large-plaque (lp) mutants we

295 ward genetic screen of N-ethyl-N-nitrosourea mutagenized Xenopus tropicalis has identified an inner e

296 everse yeast two-hybrid assay using randomly mutagenized XPF.

297 Here, we mutagenized Ydj1p and find that disrupting substrate bin

298 After mutagenizing yeast Saccharomyces cerevisiae cells, stude

299 s research we determined whether a screen of mutagenized zebrafish for nicotine preference could pred

300 In a three-generation screen of chemically mutagenized zebrafish, we identified a group of mutation