ライフサイエンスコーパス: mutant lacking

1 Most importantly, an RNF126 mutant lacking 11 amino acids that is responsible for th

2 trate that expression of a priming-deficient mutant lacking 17 residues of the domain 3a hinge-loop (

3 chromatic regions, lose DNA methylation in a mutant lacking 22- to 24-nt sRNAs (dicer-like 2, 3, 4 tr

4 We further report that a Nup1 mutant lacking 36 C-terminal residues recapitulates the

5 NleE mutants lacking (49)GITR(52) were unable to methylate TA

6 ough this result also occurred in a BPV-1 E2 mutant lacking a previously identified phosphorylation s

7 A DeltapstA1 mutant lacking a Pst phosphate uptake system component i

8 grow in co-culture with a G. sulfurreducens mutant lacking a trans-outer membrane porin-cytochrome p

9 Mutants lacking a channel protein or defective in channe

10 namics, ER organization is also defective in mutants lacking a functional ARK1.

11 Fungal mutants lacking a functional Fusarium (F)-RALF peptide f

12 strate that the Alix Bro1 domain rescues FIV mutants lacking a functional TSG101-interacting motif, i

13 RecADeltaC17 mutants, lacking a C-terminal autoregulatory flap, also

14 transcriptional changes that occur in mut-16 mutants, lacking a key protein in the RNAi pathway, at e

15 own here to be impaired by as much as 35% in mutants lacking ABCB19, an ATP-binding cassette membrane

16 s or overexpressing a dominant negative p300 mutant lacking acetyltransferase activity in mouse muscl

17 A B. bronchiseptica mutant lacking ACT produced more biofilm than the parent

18 In cv Pinot Noir, a red-berried grapevine mutant lacking acylated anthocyanins, Vv3AT contains a n

19 he present studies showed that the S. aureus mutant lacking adenosine production (adsA strain) increa

20 Mutants lacking AHR1 were defective in growth, alkaliniz

21 a phenotype similar to the one observed in a mutant lacking all 6 mce operons suggesting a pleiotropi

22 An APP mutant lacking all C-terminal lysines underwent the most

23 By expression in a mutant lacking all LHCSR isoforms, residues Asp(117), Gl

24 Here, we report on the construction of a mutant lacking all monomeric LHC proteins but retaining

25 A mutant lacking all seven major glucose transporters was

26 A Pseudomonas aeruginosa mutant lacking all three known iron acquisition systems

27 Knockout mutants lacking all EBs are viable and fertile and displ

28 In this study, we generated zebrafish mutants lacking all four zebrafish Mesp genes by using T

29 urface expression was rapidly lost, even for mutants lacking all known endocytosis motifs.

30 A mutant lacking an ATP-binding cassette transporter exhib

31 Among 13 mutants screened, a mutant lacking an extracellular polysaccharide (EPS) loc

32 umbia-0, but is able to do so effectively in mutants lacking at least two of the four Arabidopsis DCL

33 ssrS mutants lacking Bb6S RNA were compromised for infectivit

34 A Flower mutant lacking binding sites for the endocytic adaptor A

35 stored by expression of GAB2 but not by GAB2 mutants lacking binding sites for its effectors phosphat

36 ir spaces; reduced methylesterification in a mutant lacking both CGR-genes 2 and 3 (cgr2/3) resulted

37 rescued by two RNF4 SIMs; and (iv) a PML II mutant lacking both lysine SUMOylation and SIM was not r

38 Most importantly, we demonstrate that a mutant lacking both of these proton pumps is conditional

39 PlcA, PlcB, or ActA grew normally, a double mutant lacking both PlcA and ActA failed to grow in wild

40 The unfolded mutant lacking both types of epitopes displayed signific

41 In contrast, female fates can be restored in mutants lacking both cyp19a1a and dmrt1, and prolonged i

42 Mutants lacking both eIFiso4G isoforms showed the most o

43 HSV mutants lacking both gE and US9 fail to properly assembl

44 We previously described HSV double mutants lacking both gE and US9 that failed to transport

45 Mutants lacking both hoxa13b and hoxd13a in combination

46 ms to be involved, since dpe2-1/phs1a double mutants lacking both PHS1 and the cytosolic DISPROPORTIO

47 t-synaptic currents are eliminated in double mutants lacking both scaffolds.

48 Phenotypic analysis of a suite of double mutants lacking both SS5 and other proteins implicated i

49 The mutant lacking btrS recruited many more B and T cells in

50 We then constructed two deletion mutants lacking C-terminal regions and mutants with poin

51 Mutants lacking calcineurin, or its client CrzA, display

52 omal H2O2 production in Arabidopsis thaliana mutants lacking CATALASE2 (CAT2) activity (cat2-2).

53 ed and membrane-localized in a R. capsulatus mutant lacking CcoA, these transporters were unable to a

54 Moreover, mutants lacking cereose germinated faster than the wild

55 mmetry and equilibrium are present in repair mutants lacking certain repair chaperones, suggesting th

56 ntact mice and changes in gait expression in mutants lacking certain types of commissural interneuron

57 A Chlamydomonas reinhardtii mutant lacking CGL71, a thylakoid membrane protein previ

58 An Arabidopsis ddcc mutant lacking CHH and CHG methylation does not affect s

59 Mutants lacking CIPK23 were found to exhibit impaired st

60 e discovered that Corynebacterium glutamicum mutants lacking components of the pupylation machinery s

61 n of aberrant supercomplexes in CcO assembly mutants lacking Cox2 or Cox4 subunits.

62 labeling, and ribosome profiling analyses of mutants lacking CP33B and/or CP33C detected some decreas

63 istinct phototransduction systems, we tested mutants lacking CRY and mutants with disrupted opsin-bas

64 ponses to blue light significantly differ in mutants lacking CRY, as well as mutants with disrupted o

65 However, we find that FtsN mutants lacking cysteines give rise to filamentous growt

66 o independent cerk1 null mutants; a deletion mutant lacking D14L, and with D14L complemented as well

67 l B-cell development, whereas an Hdac3 point mutant lacking deacetylase activity failed to complement

68 By systematically imaging mutants lacking defined T4PM proteins or with individual

69 Arabidopsis (Arabidopsis thaliana) xxt1 xxt2 mutants lacking detectable xyloglucan are viable, they d

70 Interestingly, an MHV68 mutant lacking deubiquitinase (DUB) activity, embedded w

71 Furthermore, mutants lacking Dicer in gonadotropes displayed severely

72 Adenovirus mutants lacking E1B55K or E4orf6 display defects in vira

73 Here we examined mutants lacking each of the major neurotransmitters in C

74 We evaluated the InlB surface retention in mutants lacking each of these two genes, and found that

75 bound by protein VII during infection with a mutant lacking early region E4.

76 g in Chlamydomonas in 1995, the isolation of mutants lacking easily ascertained newly acquired phenot

77 Ribosome profiling of mutants lacking eIF4B or with impaired eIF4A or Ded1 act

78 Cre and Flp recombinase mutants lacking either arginine can be rescued by compen

79 Purified enzymes inhibit fungal growth and mutants lacking either GH18 grow normally on cellulose a

80 Moreover, Top3beta mutants lacking either its RNA-binding domain or catalyt

81 Arabidopsis (Arabidopsis thaliana) knock-out mutants lacking either phot2 or chup1 and analyzed the k

82 Targeted P. patens knockout mutants lacking either PpSMF1 or PpSCRM1 develop gametop

83 In addition, mutants lacking either SPN or SLO are significantly atte

84 Pol I mutants lacking either the heterodimeric subunit Rpa34.5

85 s required the full-length Peg3 as truncated mutants lacking either the N-terminal SCAN domain or the

86 vICA-deficient mutants, lacking either UL36 or M36, exhibit greater sus

87 Mutants lacking elements of the stringent response - (p)

88 A mutant lacking endocarditis- and biofilm-associated pili

89 ression restores cholesterol export to yeast mutants lacking endogenous Pry1 and Pry2.

90 either BLOC-1 or Msb3, but it also occurs in mutants lacking endosome-vacuole fusion machinery such a

91 r overexpressing ESV1 or LESV, and of double mutants lacking ESV1 and another protein necessary for s

92 ated a comprehensive library of S. sanguinis mutants lacking every nonessential gene.

93 we determined resection at IR-DSBs in WT and mutants lacking exonuclease1 or Sgs1 helicase.

94 countermeasures and that vaccination with a mutant lacking expression of the protein provides a plat

95 By using isogenic A. baumannii mutants lacking expression of virulence effector protein

96 and flgII-28 was greatly reduced in a tomato mutant lacking Fls2 and Fls3, but induction of Fls3 gene

97 Salmonella mutants lacking FraB are highly attenuated in mouse mode

98 hese results, together with our finding that mutants lacking fraD or the fra island are not attenuate

99 Plants of T-DNA insertion mutants, lacking FUM2, show marked differences in their

100 Mutants lacking functional FDH-O had abolished PGRP-indu

101 The mutant lacking galactofuranose exhibited a decreased gro

102 fluconazole resistance was also observed in mutants lacking Glo1, a Mrr1-independent MG catabolic en

103 Here we show that, unexpectedly, an Mtb mutant lacking GLPX grows on gluconeogenic carbon source

104 Moreover, an analysis of Arabidopsis mutants lacking GLS showed an extensive seed-specific im

105 Mutants lacking glucose I of the LPS outer core failed t

106 Grafting of 1.0-cm stem sections from mutants lacking GLUTAMATE RECEPTOR-LIKE 3.5 or the mutan

107 pairs promoter nucleosome eviction even in a mutant lacking H2A.Z.

108 Furthermore, mutants lacking HCF136, which mediates an early step in

109 We show that mutants lacking hira-1, an evolutionarily conserved H3.3

110 Transfection of a NME1 site-directed mutant lacking histidine protein kinase activity but ret

111 JMJD1A (wild type or mutant lacking histone demethylase activity) bound to HU

112 Furthermore, mutants lacking histone H3.3 have a late-onset defect si

113 Isogenic NTHI strain 86-028NP mutants lacking hktE and pdgX had increased susceptibili

114 nt strain efficiently outcompeted the double mutant lacking HMW1 and HMW2.

115 atxA transcription is reduced 2.5-fold in a mutant lacking HPr and EI, and that this change is suffi

116 ts confirmed that Synechococcus sp. PCC 7002 mutants lacking hydrocarbons exhibit reduced thylakoid m

117 This prompted the construction of an MCMV mutant lacking ie611 but retaining the coding capacity f

118 scripts prompted the construction of an MCMV mutant lacking ie611 but retaining the coding capacity f

119 nstead, for static E. coli, the diffusive T4 mutant lacking Ig domains outperformed the subdiffusive

120 Using mutants lacking individual chemoreceptors, we found that

121 rp1 interactions, such that recombinant Drp1 mutants lacking insert B form a stable complex with Mff.

122 Moreover, both WT CLASP2 and a CLASP2 mutant lacking its C-terminal domain, which mediates its

123 under conditions of oxidative stress and in mutants lacking key antioxidants.

124 Mutants lacking KIN-29, the C. elegans homolog of a mamm

125 These results did not occur with 130b mutants lacking lbtU or lbtC, indicating that both endog

126 The severest phenotype-observed in a mutant lacking Lhca4 (DeltaLhca4)-displayed a 69% reduct

127 and B form poor biofilms, but F. tularensis mutants lacking lipopolysaccharide O-antigen, O-antigen

128 the best characterized function of mtFAS, as mutants lacking lipoylation have an intact ETC.

129 red for cardiac regeneration in zebrafish as mutants lacking lymphatics display severely impaired reg

130 We further show that mutants lacking lysosome-related organelles are defectiv

131 We show here that replication of an MCMV mutant lacking m166 is also severely attenuated during v

132 escue the islet beta-cell defects in a mouse mutant lacking MafA in beta-cells.

133 ect can be mimicked with "melanin ghosts"; a mutant lacking melanin showed reduced platelet stimulati

134 E. coli mutants lacking mepK and another d-Ala-mDAP-specific end

135 h was mitigated upon co-expression of an Eos mutant lacking miR-17 target sites.

136 e flux, we generated conditional Cox10 mouse mutants lacking mitochondrial respiration in astrocytes,

137 As such, the mkp1 mutant lacking MKP1 displays enhanced PAMP responses and

138 Mutants lacking MltG were also shown to have longer glyc

139 In contrast, mutants lacking motility (DeltamotB) or chemotaxis (Delt

140 In contrast, Vibrio mutants lacking motility traits surrender to host spatia

141 Infection of cells with a BTV mutant lacking NS4 results in increased synthesis of IFN

142 ramatic phenotype of the ntrc-trxf1f2 triple mutant, lacking NTRC and f-type Trxs, was also suppresse

143 Arabidopsis mutants lacking NTRC (ntrc) displayed a striking photosy

144 e production of viable pollen was reduced in mutants lacking one of the three main proteins involved

145 We investigated a deletion mutant lacking only this alpha-helix in stable cell line

146 and two affect virulence in vivo; and (iv) a mutant lacking ORF25 is highly attenuated but induces mo

147 ce of male mice for females is eliminated in mutants lacking oxytocin, a neuropeptide modulating soci

148 Mutants lacking p38 MAPK components pmk-1 or sek-1 resem

149 e overexpression of full-length IL1RAPL1 and mutants lacking part of C-terminal domains leads to simp

150 is effect is abolished when we overexpressed mutants lacking part of N-terminal domains, indicating t

151 Although PBP1 is an essential protein, a mutant lacking PBP1 transpeptidase activity is viable, s

152 -type allele of uppS, also promoted lysis in mutants lacking PBP1B or bPBP activity.

153 onuclear cells, while its isogenic nonmotile mutant lacking PF resulted in significantly diminished c

154 uitable for phosphotransfer by PKA, and CFTR mutants lacking phosphorylatable serines--that PKA effic

155 An RPA32 mutant lacking phosphorylation sites fails to recruit PR

156 We also observed that vph1 mutants lacking PI(3,5)P2 activation have enlarged vacuo

157 Mutants lacking plastid-encoded RNA polymerase-associate

158 CAM mutants lacking PPC have not been described.

159 In mutants lacking PpNOG2 function, transcript levels of CL

160 ession and cell death were observed in clock mutants lacking proper CCA1 and LHY function.

161 nctional complementation of L. monocytogenes mutants lacking prsA2.

162 In comparison with the wild type, growth of mutants lacking Psb28-1 and Psb27, but not Psb28-2, was

163 Phenotypic characterization of mutants lacking PSB33 revealed reduced amounts of PSII-L

164 ancy in the dark and differ in this way from mutants lacking PSII for other reasons.

165 th severe growth defects being observed in a mutant lacking PTOX2, the major plastoquinol oxidase.

166 s Rad51 from undamaged sites on chromosomes; mutants lacking Rad54 accumulate nonrepair-associated co

167 Double mutants lacking receptor tyrosine phosphatases (PTP) Ptp

168 are almost identical to those of a receptor mutant lacking residues previously believed to induce ol

169 ga and its role in assembly of RNAP, E. coli mutants lacking rpoZ (codes for omega) are viable due to

170 ecause starch sheath granules, or plates, in mutants lacking SAGA1 are more elongated and thinner tha

171 e GIT colonization phenotypes of E. faecalis mutants lacking selected sortase-dependent proteins (SDP

172 During IFS formation, mutants lacking SEP4 could produce reactive oxygen speci

173 Furthermore, mutants lacking serotonergic neurons and mutants that ca

174 Additionally, mutants lacking serratiochelin were significantly outcom

175 histone H3 and RNA polymerase II (Pol II) in mutants lacking single or multiple cofactors to address

176 cued by adding back wild-type Nap1 but not a mutant lacking sites subject to posttranslational modifi

177 An Mtb mutant lacking SL-1, MtbDeltapks2, shows attenuated lyso

178 Mtb organic extracts from mutants lacking SL-1 synthesis cannot activate neurons i

179 In Drosophila tok mutants lacking Slit cleavage, midline repulsion of axon

180 ore, A549 human lung cells infected with GAS mutants lacking SP-PTP displayed increased Ser-/Thr-/Tyr

181 Phenotypic analysis of GAS mutants lacking SP-PTP revealed that the phosphatase act

182 Mutants lacking SPCH do not produce stomata or lineages.

183 ific response, we have generated Arabidopsis mutants lacking specific combinations of Galpha and Gbet

184 ft-right synchronous hopping-like pattern in mutants lacking specific neuron classes, and speed-depen

185 mice and the changes in coordination seen in mutants lacking specific neuron classes.

186 We found that isogenic mutants lacking SPN, SLO, and both toxins are equally im

187 licited an increased inhibition of S. aureus mutants lacking T7SS effectors EsxC, EsxA and EsxB, or t

188 Mutants lacking TAG or impaired of TAG hydrolysis show s

189 We show that pox-neuro (poxn) mutants lacking taste function in the legs and labial pa

190 he progressive neurological deficits seen in mutants lacking TBs; and 2) the insertional mutation in

191 t, an ORF2 nuclear localization mutant, or a mutant lacking the 5 protein kinase A or C phosphorylati

192 rnica multiple nucleopolyhedrovirus (AcMNPV) mutant lacking the antiapoptotic gene p35 (vAc(P35)) and

193 to the level of GAA knock-out mice, as did a mutant lacking the Atg8 family interacting motif (AIM) a

194 icked by the expression of a truncated OPHN1 mutant lacking the BAR domain, demonstrating that the BA

195 prisingly, the growth of an L. monocytogenes mutant lacking the c-di-AMP-synthesizing enzyme cdaA is

196 An Arg mutant lacking the C-terminal calponin homology actin-bi

197 found that the deletion mutants and a double mutant lacking the C94-C111 and C95-C112 disulfide bonds

198 lasma mycoides subsp. capri or an engineered mutant lacking the capsular polysaccharide, galactofuran

199 ITF1 expression and that the JA biosynthetic mutant lacking the CITF1- and SPL7-regulated genes, LOX3

200 capitulate the phenotype of a JA-insensitive mutant lacking the COI1 receptor.

201 ely impaired when complementing with a TgADF mutant lacking the corresponding residue (Lys-68).

202 on, as DCs expressing a high-mobility ICAM-1 mutant lacking the cytoplasmic domain exhibit diminished

203 permissive for replication of an HIV-1 gp41 mutant lacking the cytoplasmic tail.

204 We found that a mutant lacking the deubiquitinase (DUB) activity of the

205 in prt6, an Arabidopsis thaliana N-end rule mutant lacking the E3 ligase PROTEOLYSIS6 (PRT6).

206 WbaP(Mx) complemented a Salmonella enterica mutant lacking the endogenous WbaP that primes O-antigen

207 An LRIG1 mutant lacking the ErbB3 interaction motif was insuffici

208 We used this model to analyze a MHV-68 mutant lacking the expression of all miRNAs.

209 of mastigonemes using a genetically modified mutant lacking the fibrous structures.

210 the role of GlcNAc metabolism using a triple mutant lacking the genes required to metabolize exogenou

211 An Arabidopsis mutant lacking the glucosyl-transferase, STARCH SYNTHASE

212 Furthermore, overexpression of Mag1 in a mutant lacking the H2A and H3 N-tails rescues base excis

213 ulled down by nesprin-1-alpha2, but not by a mutant lacking the highly-conserved STAR domain (18 amin

214 relevant structures, because an A. fumigatus mutant lacking the hydrophobin protein induced stronger

215 In addition, a DeltapstA1 DeltaesxN mutant lacking the hypersecreted ESX-5 substrate EsxN re

216 In a dap160 rescue mutant lacking the interaction between Dap160 and synaps

217 ould be rescued by GFP-BAF, but not by a BAF mutant lacking the Lap2, emerin, Man1 (LEM)-protein bind

218 TIS11d, the E220A mutant and the truncation mutant lacking the last two residues (D219/E220) were st

219 Wild-type Ara h 2 and a mutant lacking the loops containing linear IgE epitopes

220 tures of the cleaved form and of an inactive mutant lacking the membrane-spanning region.

221 A mutant lacking the methionine-rich hairpin domain charac

222 An M. genitalium mutant lacking the MG491 segment corresponding to the pe

223 Loss of SNPH or expression of an SNPH mutant lacking the mitochondrial localization sequence r

224 KIF17 mutant lacking the motor domain translocated to nuclei a

225 that of the t-LM produced by a C. glutamicum mutant lacking the mptA gene, encoding a membrane alpha1

226 e, we address this issue by studying a HSV-1 mutant lacking the mucin-like domain in gC and the corre

227 A truncation mutant lacking the N terminus (DeltaN) was found to alte

228 Our complementation studies, using a mutant lacking the nitrate/proton symporter NasA from th

229 ith the N terminus of TAP, whereas an HDAg-L mutant lacking the NLS failed to interact with full-leng

230 Unexpectedly, a gp210/Nup210 mutant lacking the NPC-targeting transmembrane and C-ter

231 ve-attenuated herpes simplex virus 1 (HSV-1) mutant lacking the nuclear localization signal (NLS) on

232 3(Ct) ) along with oppBCDF(Ct) in an E. coli mutant lacking the Opp transporter and determined that a

233 le than that of Src, an effect lost in a Fyn mutant lacking the palmitoylation sites.

234 An R. solanacearum mutant lacking the pathogen's two extracellular nuclease

235 Notch2(DeltaPEST) allele expressing a Notch2 mutant lacking the PEST domain.

236 the sensors expressed in the wild type and a mutant lacking the PHOSPHATE TRANSPORT4;2 plastidic Pi t

237 inome-seq was also implemented for pnp1-1, a mutant lacking the processing enzyme polynucleotide phos

238 An E.coli mutant lacking the PROSC homolog (DeltaYggS) is pyridoxi

239 Infection with an HCMV mutant lacking the pTRS1 PKR binding domain resulted in

240 A MCMV mutant lacking the PVR inhibitor was attenuated in norma

241 ression was only detectable in a Tolypothrix mutant lacking the RcaE photoreceptor required for compl

242 A mutant lacking the regulatory protein LldR failed to ind

243 In this mutant lacking the Snf1-mediated positive feedback loop,

244 rion formation is particularly elevated in a mutant lacking the Sod1 Cu,Zn-superoxide dismutase.

245 is inhibited in a Chlamydomonas reinhardtii mutant lacking the transcription factor Pi Starvation Re

246 A CHIP mutant lacking the U-box domain, which is responsible fo

247 Significantly, KSHV LANA mutants lacking the acidic domain reader sequence are de

248 nt increase in cAMP, which still occurred in mutants lacking the adenylate cyclases ACG or ACR, or th

249 Notably, PAO1 mutants lacking the alkB2 gene fail to form an elastic l

250 Monarch mutants lacking the BMAL1 C terminus including the TAD e

251 Hypersensitivity of taf1 mutants lacking the C-terminal bromodomain to X-rays and

252 absence of added phage or plasmid and since mutants lacking the CRISPR array or any one of the other

253 Mutants lacking the GLFG domain of Nup116 displayed decr

254 fective in cellulose synthesis and xxt1 xxt2 mutants lacking the hemicellulose xyloglucan, stomatal a

255 p38 MAPK components pmk-1 or sek-1 resemble mutants lacking the hypoxia response component and proly

256 Here, we compare the phenotype of sae2 mutants lacking the main CDK (sae2-S267A) or Mec1 and Te

257 in yeast, this chaperone is essential, with mutants lacking the major UMP1a and UMP1b isoforms displ

258 However, MinE mutants lacking the MinE membrane-targeting sequence sti

259 e we characterized Chlamydomonas reinhardtii mutants lacking the mitochondrial alternative terminal r

260 Truncation mutants lacking the motor region failed to localize to f

261 le complementation system, we find that CTCF mutants lacking the N-terminus cannot insulate TADs prop

262 alysis of Arabidopsis (Arabidopsis thaliana) mutants lacking the NMD-related proteins UPF3, UPF1, and

263 athogen Candida albicans, deep sequencing of mutants lacking the orthologous protein, Zfs1, revealed

264 te residues, deletion of lpxE or eptA led to mutants lacking the P-Etn group, with consequently incre

265 Using Arabidopsis (Arabidopsis thaliana) mutants lacking the peroxisomal CATALASE2 (cat2-2) that

266 Disruption of degradosome assembly in mutants lacking the polynucleotide phosphorylase (PNPase

267 P growth was delayed in cell-death-deficient mutants lacking the positive cell death regulator ORESAR

268 Mutants lacking the PP2A methyltransferase or the effect

269 While mutants lacking the PrfA-dependent virulence factor PlcA

270 med lineage tracing experiments and analyzed mutants lacking the Prox1 transcription factor, a master

271 s LMW PBPs is critical for bacterial growth; mutants lacking the related protein DacA-2 and/or homolo

272 Mutants lacking the sch gene cluster lost their iron-che

273 er susceptibility to CD8 T cell control than mutants lacking the set of immunoevasins known to disrup

274 Hence, we could select double mutants lacking the T-DNA already in the first offspring

275 In contrast, mutants lacking the TAD alpha-helix but retaining the mo

276 e modifications, we generated M. acetivorans mutants lacking the three known modification genes in al

277 PSI mutants lacking the U1 snRNP-interacting domain (PSIDelt

278 Pathological Tau mutants lacking the vesicle binding domain still localiz

279 produced single-cell colonies of C. merolae mutants, lacking the PsbQ' subunit in its PSII complex b

280 A BubR1 mutant lacking these motifs is defective in MCC maintena

281 t survival on ciprofloxacin is diminished in mutants lacking these enzymes.

282 We assessed mutants lacking these glycans for expression and functio

283 In Escherichia coli, mutants lacking these proteins often have no phenotype,

284 exogenous acids/bases rescue the reaction in mutants lacking these residues, can estimate these catal

285 o wild-type Synechocystis PSII and a D1-D61A mutant lacking this hydrogen-bonding interaction demonst

286 gests these polysaccharides extracellularly, mutants lacking this ability are outcompeted.

287 SscS plays a role during swarming, and mutants lacking this chemoreceptor swarm faster and prod

288 ssible basis for the phenotypes of H. pylori mutants lacking this enzyme.

289 otably, experiments against Candida albicans mutants lacking those genes showed resistance to the com

290 at the albino plastid protein import2 (ppi2) mutant lacking Toc159 protein import receptors have acti

291 tant seedlings supported the hypothesis that mutants lacking tonoplast proton pumps were defective in

292 almEFG and the polymyxin B MIC increased in mutants lacking toxRS or leuO Conversely, leuO overexpre

293 ses included wild type C. elegans but also a mutant lacking two HS sulfotransferases (hst-6 hst-2), a

294 Mutants lacking UL128-131 replicate well on fibroblasts

295 In C. elegans mutants lacking unc-75 or its targets, regenerating axon

296 ssion observed in vivo in intact mice and in mutants lacking V0V or all V0 CINs.

297 for IFIT1 restriction of a human coronavirus mutant lacking viral N1 methylation.

298 ab49DeltafbaA was compared to other isogenic mutants lacking virulence genes known to be disproportio

299 Unlike wild-type V. cholerae, mutants lacking wigR fail to recover following exposure

300 contributor to carotenoid composition, with mutants lacking ZEP activity showing a remarkable 6-fold