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1 dent growth of the M. smegmatis tam deletion mutant strain.
2 e domain, is sufficient to complement a rocA mutant strain.
3 uted to an altered membrane potential in the mutant strain.
4 the DeltawcaM DeltacsgA DeltayihO DeltabcsE mutant strain.
5 ated iron acquisition is impaired in an sbnI mutant strain.
6 gnificantly upregulated in the fabT deletion mutant strain.
7 h a newly characterized curved-rod Delta1228 mutant strain.
8 sistant to oxidants than a catalase-deletion mutant strain.
9 type M59 GAS, we constructed an isogenic mga mutant strain.
10 failed to support growth of an E. coli acpP mutant strain.
11 x II failed to support growth of the E. coli mutant strain.
12 pts of intron-spliced isoforms in the MoHMT1 mutant strain.
13 perature-sensitive phenotype of an spo7Delta mutant strain.
14 but at a substantially lower level in a CMD1 mutant strain.
15 ut were undetectable in the pigmentless snf2 mutant strain.
16 enes were significantly reduced in the dkppx mutant strain.
17 se activity was altered in the yjbH and yjbI mutant strains.
18 f Deltainv, DeltayadA, and DeltainvDeltayadA mutant strains.
19 xposed to H pylori, including cagPAI and cgt mutant strains.
20 sequences in both wild type and degradosome mutant strains.
21 ainst the wild type virus and drug-resistant mutant strains.
22 did not lead to the development of resistant mutant strains.
23 lated RNA ends in ribonuclease wild-type and mutant strains.
24 and cellular phenotypes of the wild-type and mutant strains.
25 in both the E. coli parent and aceE deletion mutant strains.
26 d A isolated from the corresponding deletion mutant strains.
27 eading to the recovery of covR, covS or rocA mutant strains.
28 Hsp70 biology has emerged from studying ssa mutant strains.
29 eron, by developing knock-out and functional mutant strains.
30 specific antibodies via the emergence of new mutant strains.
31 compared to single Deltagra12 or Deltarop18 mutant strains.
32 tical to those of the corresponding deletion mutant strains.
33 iter, with little effect on nearly identical mutant strains.
34 microcolonies between the EmaA positive and mutant strains.
35 species: a collection of genetically related mutant strains.
36 genetic interactions in single and multiple mutant strains, (2) can identify drug targets, (3) detec
42 terized straight-rod Deltapgp1 and Deltapgp2 mutant strains, along with a newly characterized curved-
44 t (Saccharomyces cerevisiae) SEIPIN deletion mutant strain and a plant (Nicotiana benthamiana) transi
45 ry aspergillosis since a sulfate transporter mutant strain and a sulfite reductase mutant strain are
47 e are increased in both fast and slow Pol II mutant strains and the magnitude of half-life changes co
48 urement of the relative fitness of bacterial mutants, strains and species in mixed inocula in the hos
49 orphisms (n = 48), an isogenic rocA deletion mutant strain, and five isogenic rocA polymorphism mutan
50 different inoculation techniques, bacterial mutant strains, and assays for the hypersensitive respon
51 ences were examined in the single and double mutant strains, and the virulence of select strains was
52 oot architectures, including wildtype and 10 mutant strains, and we uncovered a design principle that
53 troso-guanidine mutagenesis and selection, a mutant strain Apmu4 was derived, in which the rate of lo
56 The guide sequences, editing constructs, and mutant strains are freely available to researchers to in
59 rocessing of 16S rRNA is also delayed in the mutant strain, as indicated by increased levels of precu
61 onsistent with these observations, the H273D mutant strain attenuated GAS virulence, whereas the H273
62 at the espACD regulatory region of the phoP mutant strain because of PhoP-EspR protein-protein inter
63 expression decreased in the CN3718 codY-null mutant strain but significantly increased in the SM101 c
64 proteins was not negatively affected in the mutant strains, but still the capacity for nonphotochemi
66 ed to the wild-type strain, a H201R isogenic mutant strain caused significantly larger skin lesions i
67 cytogenes infection, a reduced number of the mutant strain compared to the parental strain was observ
68 f infection with the wild-type strain or the mutant strain complemented with lipA ROS derived from th
69 ESR was partially induced in the siw14Delta mutant strain, consistent with the increased stress resi
71 gas was detected in a hydrogenase quadruple-mutant strain containing deletions in the hya, hyb, hyd,
73 ity level, we asked whether matrix-defective mutant strains could be coaxed to produce functional mat
74 r cell signaling, and the germination of rpf mutant strains could not be stimulated by the addition o
76 ingae pv tomato DC3000 and the nonpathogenic mutant strain DC3000hrpA- allowed us to establish causal
79 riptional profiling of roots inoculated with mutant strains defective in the synthesis of Nod Factor
81 activity is higher in 33277, and an isogenic mutant strain deficient for the gingipains exhibited an
83 erexpression of COY1 inhibited the growth of mutant strains deficient in fusion activity at the Golgi
84 n flux ranges and the presence or absence of mutant strains delivering flux towards pathways of inter
86 Escherichia coli, or Pseudomonas aeruginosa mutant strain DeltapopB Moreover, BMDMs deficient in IRF
87 riptional profiles were compared between the mutant strain DeltarelA [a (p)ppGpp(0) strain under gluc
88 rgeted gene deletion confirmed that isogenic mutant strains DeltaspyAD and Deltaisp2 are significantl
89 A B. pseudomallei DeltappiB (BpsDeltappiB) mutant strain demonstrates impaired biofilm formation an
90 gnificantly increased in the SM101 codY-null mutant strain, demonstrating CodY-dependent regulation d
91 er, we found that a slowly constricting fzlA mutant strain develops 'pointy' poles, suggesting that F
92 uring growth in vitro However, the DeltaphtY mutant strain did not display an increased CP sensitivit
93 Despite high expression of ACT, the rseA mutant strain did not infect the murine airway as effici
96 as the DeltaadcA, DeltaadcAII, and DeltaphtD mutant strains displayed less CP sensitivity during grow
97 the general fitness of the amoebae with the mutant strain displaying a substantial growth defect.
99 etween M. tuberculosis H37Rv and a DeltanarL mutant strain during exponential growth in broth culture
100 wild-type, rocA mutant, covS mutant and covR mutant strains during invasive infection and their fitne
102 Individual DeltatrxA and DeltatrxC deletion mutant strains each show a greater abundance of lipid pe
103 he hypothesis that vaccination with the batA mutant strain elicits protective immunity against subseq
105 ed defects in Mia40 oxidation, only one erv1 mutant strain (erv1-1) had significantly decreased activ
109 In contrast to cen9Delta mutants, cen10Delta mutant strains exhibited growth defects and were aneuplo
112 n original strategy that combined the use of mutant strains expressing catalytically inactive variant
113 strain expressing both HMW1 and HMW2 and the mutant strains expressing either HMW1 or HMW2 were able
115 A screen with S. pombe transcription factor mutant strains for growth sensitivity to the AEO fractio
116 To further elucidate regulatory controls, mutant strains for histidine kinases PhoR and AioS were
118 ld-type strain and an isogenic fabT deletion mutant strain found that between 3.7 and 28.5% of the S.
119 1;3 and OsPIP2;6 were displayed in yeast HD9 mutant strain (fps1acr3ycf1) as a result of increased B
120 ysis shows that the transmission rate of the mutant strain from mosquitoes to human is more influenti
121 representative isolates and "leaky melanin" mutant strains from each species complex to examine the
123 on techniques can be used to distinguish FKS mutant strains from wild type, but testing C. glabrata w
124 ith the increased stress resistance, and the mutant strain further induced the ESR in response to oxi
125 g mutant mice, we characterized Rhbdf1 mouse mutant strains generated by three commonly used strategi
127 nt, hopper(Bd-we), isolated from a white eye mutant strain had an intact transposase reading frame an
128 orescent reporter proteins revealed that the mutant strain had greatly enlarged peroxisomes up to 10
129 virulence characteristics, and the quadruple-mutant strain had the same (greatly attenuated) phenotyp
133 release, and an ato5Delta ATO1(G53D) double mutant strain has additive alkalinization and ammonia re
134 Y181C, Y188L, IRLL98, and K103N+Y181C HIV-1 mutant strains, highlighting the importance of the alpha
135 V. cholerae and a locked low-cell-density QS-mutant strain identified 7,240 transcriptional start sit
136 Whole genome sequencing of the wild-type and mutant strains identified a point mutation that creates
137 oci analysis, machine learning, and isogenic mutant strains identified and confirmed a one-nucleotide
138 ollowed by genome sequencing of the isolated mutant strains identified mutations that disrupt DNA dam
143 CMV infection resolution and emergence of a mutant strain in high-risk recipients of kidney transpla
146 were necessary for fitness in lasR+ and lasR mutant strains in colony biofilms grown in microoxic con
147 forming growth curves with WT, alsT and gltS mutant strains in defined medium supplemented with ammon
152 length maintenance by utilizing yku70-R456E mutant strains, in which Ku has reduced DEB and telomere
154 vironments, to characterization of different mutant strains, including those harbouring synthetic cir
155 ested by the hypersensitivity of a Deltasod1 mutant strain, increased resistance afforded by the supe
156 n and metabolism were all accelerated in the mutant strain indicative of dysregulated oxidative phosp
158 in mouse lung 24 h post infection while the mutant strain is cleared by host defense mechanisms.
159 Finally, we show that an E. faecalis epa mutant strain is deficient in intestinal colonization, c
161 munity afforded by vaccination with the batA mutant strain is predominantly mediated by IgG antibodie
163 abelled LA did not differ between the WT and mutant strains, LA induced more cell membrane damage in
168 ia and soft tissue infection models, and the mutant strain lacking production of both toxins is furth
169 in several nitrogen sources, we found that a mutant strain lacking the Mycobacterium proteasomal acti
173 iffusion in wild-type V. cholerae to that in mutant strains lacking either toxR or the toxT promoter,
176 s lysozyme resistance of L. monocytogenes as mutant strains lacking gpsB showed an increased lysozyme
182 Mongolian gerbils with an H. pylori pgdA(-) mutant strain led to significantly decreased levels of i
183 on of LipA from Xac306 and verified that the mutant strain lost most of its lipase and esterase activ
186 quire a live, stable, lipid-rich E. gracilis mutant strain, named B1ZFeL, with 40% more lipid content
187 clude the generation of large collections of mutant strains, now available for forward- and reverse-g
190 the reference strain and homozygous deletion mutant strain of CCC2, which encodes a Cu(2+)-transporti
191 compared to a DeltarelADeltaspoT (ppGpp(0)) mutant strain of E. coli, deficient in the stringent res
192 We also determine that the high-persister mutant strain of Escherichia coli, HipQ, is associated w
195 tient 103 (PA103) supernatant] or defective [mutant strain of P. aeruginosa lacking a functional type
197 easure the mechanical properties of T4P of a mutant strain of Pseudomonas aeruginosa PAO1 unable to r
200 because killed bacteria and a protease-null mutant strain of S. aureus were unable to penetrate.
201 c-psbA4 gene from Cyanothece 51142 in a 4E-3 mutant strain of the model non-nitrogen-fixing cyanobact
204 Bs2 gene since no effect was observed when a mutant strain of Xcc with a disruption in avrBs2 gene wa
205 much faster "colony surfing" still occurs in mutant strains of Bacillus subtilis lacking flagella.
208 of photoautotrophically grown wild-type and mutant strains of Chlamydomonas reinhardtii to determine
210 ease progression using Caenorhaditis elegans mutant strains of dnj-14, the worm orthologue of DNAJC5.
212 mic has been exacerbated by the emergence of mutant strains of Mtb that are resistant to frontline an
213 oughput sequencing (Hi-C) with wild-type and mutant strains of Neurospora crassa to gain insight into
214 al lesions, both capsular-defective knockout mutant strains of P. gingivalis induced less alveolar bo
220 to a toxic concentration of toluene, a tolR mutant strain or a strain overexpressing a diguanylate c
223 tii nopA::Tn or a Dot/Icm-defective dotA::Tn mutant strain present a functional innate immune respons
224 transformants of a somatic regenerator (Reg) mutant strain receiving sgRNA plasmid with glsA protospa
225 during the growth of the wild-type and sigL mutant strains reduced expression of the toxin genes, in
226 that the majority of cells in a Deltasll1130 mutant strain remained unicellular and viable after prol
227 produce an mif(-/-) strain of L. major This mutant strain replicated normally in vitro but had a 2-f
231 ic Cu(+) Analysis of DeltacopR and DeltacueR mutant strains revealed a CopR regulon composed of genes
232 scriptome analysis of the wild-type and dcl3 mutant strains revealed a further difference from higher
234 DeltadevR, DeltadevSDeltadosT, and DeltanarL mutant strains revealed that in response to nitrite prod
235 nal carbon; the core oscillator in the prd-1 mutant strain runs with a long period under glucose-suff
236 itch variability is heritable, and comparing mutant strains selectively bred to high and low penetran
240 tion in the wild type and an IsoMO-disrupted mutant strain showed that epoxyisoprene, or a subsequent
241 for correct fungal development as the AaGPx3 mutant strains showed a severe reduction in conidiation.
243 s and biological confirmation with different mutant strains showed that this life extension is due to
245 tion frequency, particularly in an ung1Delta mutant strain, suggesting that dCas9 induces mutations t
246 aexlx-gh5 rescued the movement defect of the mutant strain, suggesting that expansin and GH5 function
247 transcripts that were more abundant in dcl3 mutant strains than in wild-type cells were not due to s
248 C (11G5 strain) isolated from a patient or a mutant strain that does not produce colibactin (11G5Delt
249 we describe the genome engineering of a RF1 mutant strain that enhances suppression efficiency durin
250 enetically engineered centrin gene knock-out mutant strain that is antibiotic resistant marker free a
253 ding increasing concentrations of sulfate to mutant strains that are unable to incorporate H2S effici
254 combine phenotypic and genotypic analyses of mutant strains that suggest discrepancies in the literat
256 colonized with R. gnavus wild-type (WT) and mutant strains-the fitness of the nan mutant was signifi
257 ully restored the wild-type phenotype of the mutant strain; this indicates that P55 plays no importan
260 of Chlamydomonas reinhardtii and the use of mutant strains to analyze photosynthesis was conducted i
262 notation of new genes, and the generation of mutant strains to define the role of genes in complex en
263 strain, and five isogenic rocA polymorphism mutant strains to perform genome-wide transcript analysi
266 satisfies fluxomic data for wild-type and 25 mutant strains under different substrates and growth con
269 5 transporters confirmed that each isogenic mutant strain was significantly (P < 0.05) impaired in c
271 ii, we observed that the growth of DeltacsrA mutant strains was inhibited in the presence of amino ac
272 xpression by epithelial cells exposed to psm mutant strains was significantly increased compared to t
276 S(0) globules from a Chlorobaculum tepidum mutant strain were purified and used to show that the wi
281 differences in MICs between WT and DeltaTolC mutant strains were not reflected by equal differences i
282 ptation, exocytosis, and endocytosis in sec3 mutant strains were similarly alleviated by mutation of
284 d Pseudomonas putida G7 Y1, a nonchemotactic mutant strain, were simultaneously introduced into the s
285 ExaF reduces methanol sensitivity in the fae mutant strain when lanthanides are present, providing ev
286 egulated by RpoE, and surprisingly, the rseA mutant strain where RpoE activity was elevated expressed
288 a consistent failure of C. reinhardtii vtc1 mutant strains, which are deficient in polyphosphate syn
291 nserted into the C. besciigenome, creating a mutant strain with its S-layer extensively decorated wit
292 ion with either wild-type cryptococci or the mutant strain with reduced surface xylose; although iBAL
294 sporter mediated this increase, we generated mutant strains with a deletion of SPE1 or SPE2 combined
295 generate and phenotypically characterize 29 mutant strains with deletions of individual transporter
297 hpA The expression of uhpT was absent in the mutant strains with uhpT deletion and was not inducible
298 ing molecular mass in both the wild-type and mutant strains with various subsets of phenylalanine-gly
300 whereas in the csr-1 partially rescued null mutant strain (WM193), this mark is ectopically deposite