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1 We suggest that these cells may be myeloid derived suppressor cells.
2 ing Tol-DC, Rapa-DC, DC-10, and PGE2-induced myeloid-derived suppressor cells.
3 g macrophages and granulocytic and monocytic myeloid-derived suppressor cells.
4 ritical for immune suppressive activities of myeloid-derived suppressor cells.
5 a receptor 1 expressed on tumor infiltrating myeloid-derived suppressor cells.
6 limited to F4/80(+) macrophages and Ly-6C(+) myeloid-derived suppressor cells.
7 onment that harbored more M2 macrophages and myeloid-derived suppressor cells.
8 and metastasis associated with expansion of myeloid-derived suppressor cells.
9 ronment by decreasing regulatory T cells and myeloid-derived suppressor cells.
10 ich involves T regulatory, B regulatory, and myeloid-derived suppressor cells.
11 educe infiltration of T regulatory cells and myeloid-derived suppressor cells.
12 , B cells, NK cells, regulatory T cells, and myeloid-derived suppressor cells.
13 g endothelial, haematopoietic progenitor and myeloid-derived suppressor cells.
14 decreasing cancer-associated fibroblasts and myeloid-derived suppressor cells.
15 ggested that these cells belong to monocytic myeloid-derived suppressor cells.
16 e composition of tumor-infiltrating Treg and myeloid-derived suppressor cells.
17 une system by triggering the accumulation of myeloid-derived suppressor cells.
18 n was found, which could be characterized as myeloid-derived suppressor cells.
19 dence of myeloid leukemias and production of myeloid-derived suppressor cells.
20 cells and natural killer cells and decreased myeloid-derived suppressor cells.
21 ramming normal myeloid cells into functional myeloid-derived suppressor cells.
22 low-density neutrophils (LDNs)/granulocytic myeloid-derived suppressor cells.
27 MerTK is crucial for subsequent expansion of myeloid-derived suppressor cells and for promoting their
28 TME by decreasing the presence of monocytic myeloid-derived suppressor cells and increasing the pres
29 environment characterized by an abundance of myeloid-derived suppressor cells and inhibition of cytot
31 esulted in the recruitment of both monocytic myeloid-derived suppressor cells and macrophages, thereb
32 expression of CXCL3, which binds to CXCR2 on myeloid-derived suppressor cells and promotes their migr
33 ty is attenuated by cell populations such as myeloid-derived suppressor cells and regulatory T cells,
34 nt of immunosuppressive cell subsets such as myeloid-derived suppressor cells and regulatory T cells.
35 ystemic immunoregulatory mediators TGF-beta, myeloid-derived suppressor cells and regulatory T-cells.
36 mour-activated ILC2s secrete IL-13 to induce myeloid-derived suppressor cells and support tumour grow
37 ls, increases the number of granulocyte-like myeloid-derived suppressor cells (and their expression o
38 immunosuppression in cancer (in the form of myeloid-derived suppressor cells) and, more recently, in
39 in PD-1(+)Lag3(+) T cells and CD11(+)Gr1(+) myeloid-derived suppressor cells, and changes in the che
40 ils, dendritic cells, innate lymphoid cells, myeloid-derived suppressor cells, and natural killer cel
41 by regulatory T cells, type II macrophages, myeloid-derived suppressor cells, and other immunosuppre
42 mber of M2-type macrophages and granulocytic myeloid-derived suppressor cells, and protumor T-regulat
43 ation, namely macrophages, Langerhans cells, myeloid-derived suppressor cells, and regulatory T and B
44 ted with increases in regulatory T cells and myeloid-derived suppressor cells, and the leukemic cells
45 roblasts, the hematopoietic stem cell niche, myeloid-derived suppressor cells, and the sympathetic ne
46 r T-cell function, and expansion of immature myeloid-derived suppressor cells are all contributory.
47 d tumor polymorphonuclear cells/granulocytic myeloid-derived suppressor cells are due to the loss of
50 , including tumor-associated macrophages and myeloid-derived suppressor cells, are abundant in the HC
51 d with a large expansion of Gr-1(+) CD11b(+) myeloid-derived suppressor cells, as well as elevated le
52 enitor cells, which are rapidly exploited as myeloid-derived suppressor cells at the cost of tumor-re
53 hibited accumulation of CD11b+Gr1intF4/80int myeloid-derived suppressor cells at the resection margin
54 ncreatic cancer, predominantly in neutrophil/myeloid-derived suppressor cells, but rarely in tumor ce
55 ppressive milieu mediated by M2 macrophages, myeloid-derived suppressor cells, CD1d(hi)CD5(+) regulat
56 he complex protein cargo of exosomes shed by myeloid-derived suppressor cells collected under high an
57 tant mice exhibited increased recruitment of myeloid-derived suppressor cells, consistent with protec
58 tumor site, including regulatory T cells and myeloid-derived suppressor cells, correlating with an in
59 ger-associated molecular patterns expands BM myeloid-derived suppressor cells, creating a feed-forwar
60 with AP had greater numbers of macrophages, myeloid-derived suppressor cells, dendritic cells, and g
61 promoted M2-like macrophage polarization and myeloid-derived suppressor cell differentiation, respect
62 ibitory effect of phenformin on granulocytic myeloid-derived suppressor cell-driven immune suppressio
63 may be due to depletion of T-regulatory and myeloid-derived suppressor cells during TB infection.
64 These results document the generation of myeloid-derived suppressor cells during TB, suggesting t
65 from dendritic cell (DC) differentiation to myeloid-derived suppressor cell expansion during tumour
66 acrophages, tolerogenic dendritic cells, and myeloid-derived suppressor cells, for the induction of t
67 lar, phenotypically and functionally, to the myeloid-derived suppressor cells found in cancer because
68 Cs), which are phenotypically similar to the myeloid-derived suppressor cells found in patients with
72 to a compensatory emergence of granulocytic myeloid-derived suppressor cells (G-MDSCs) that mediated
73 dendritic cells, suppressor macrophages, and myeloid-derived suppressor cells, generated in vitro fro
74 ulatory cells (Treg), Th17, and granulocytic myeloid-derived suppressor cells (gMDSC) were increased
75 th DIPG with below-median baseline levels of myeloid-derived suppressor cells had prolonged OS compar
77 tes such as tumor associated macrophages and myeloid derived suppressor cells in the tumor microenvir
78 decreased the frequency of immunosuppressive myeloid-derived suppressor cells in a syngeneic TNBC mou
79 D33+S100A9+ cells, the phenotype typical for myeloid-derived suppressor cells in cancer or immature m
80 s in vivo and found they differentiated into myeloid-derived suppressor cells in early metastatic sit
81 phenformin selectively inhibits granulocytic myeloid-derived suppressor cells in spleens of tumor-bea
82 st cancer cells revealed the accumulation of myeloid-derived suppressor cells in the lung and liver.
83 elial cells not only reduced tumor-promoting myeloid-derived suppressor cells in the lung, but also d
84 C5a receptor deficiency, which also lessens myeloid-derived suppressor cells in the premetastatic ni
85 he expansion of neutrophils and granulocytic myeloid-derived suppressor cells in the tumor microenvir
86 nd reduces the percentage of macrophages and myeloid-derived suppressor cells in the tumor microenvir
87 uppressive cytokines, including TGF-beta, by myeloid-derived suppressor cells in tumor-draining lymph
88 ted kinase pathway inhibition and to inhibit myeloid-derived suppressor cells in various melanoma mod
90 (mMDSC) and granulocytic (gMDSC) subsets of myeloid-derived suppressor cells infiltrate in the prima
91 tion and tumor cell killing while decreasing myeloid-derived suppressor cell infiltration and IL10 pr
92 also stabilizes the suppressive function of myeloid-derived suppressor cells, inhibits the release o
93 ion by inducing differentiation of monocytic myeloid-derived suppressor cells into highly immunosuppr
94 C-derived exosomes in the differentiation of myeloid-derived suppressor cells into macrophages, which
95 bitory cells, such as regulatory T cells and myeloid-derived suppressor cells, into the tumour microe
96 ut of Wt1 in endothelial, haematopoietic and myeloid-derived suppressor cells is sufficient to cause
97 munosuppressive neutrophils (or granulocytic myeloid-derived suppressor cells), is resistant to ICB,
98 characterized by a balanced distribution of myeloid-derived suppressor cell-like and APC-like myeloi
101 l subsets include monocytic and granulocytic myeloid-derived suppressor cells (M- and G-MDSCs) define
102 5) there is an early recruitment of monocyte-myeloid-derived suppressor cells (M-MDSCs) and neutrophi
104 iltration of neutrophils, T cells, monocytic myeloid-derived suppressor cells (M-MDSCs), and group 2
105 ed suppressor cells (PMN-MDSCs), mononuclear myeloid-derived suppressor cells (M-MDSCs), and Lox-1(+)
106 expression profiles in innate cells, such as myeloid-derived suppressor cells, macrophages, and dendr
107 munosuppressive myeloid cells expressing the myeloid-derived suppressor cell marker S100A9 only in a
108 rived conditioned medium differentiated into myeloid derived suppressor cells (MDSC) (CD33(+)CD11b(+)
109 e activation, have an increased frequency of myeloid derived suppressor cells (MDSC) and are at incre
111 d with tumor-associated macrophage (TAM) and myeloid-derived suppressor cell (MDSC) infiltration in t
113 igrated to the stomach, where they exhibited myeloid-derived suppressor cell (MDSC) markers and acqui
114 unosuppressive microenvironment by promoting myeloid-derived suppressor cell (MDSC) proliferation and
115 34(+) (fibrocytes) and (ii) CD45(+) CD34(-) [myeloid-derived suppressor cell (MDSC)-like fibrocytes]
116 ription, leading to mobilization of immature myeloid-derived suppressor cells (MDSC) and enhancing th
117 ruitment and accumulation of lung-associated myeloid-derived suppressor cells (MDSC) and MDSC-derived
118 nt (TIME) of LM, wherein the accumulation of myeloid-derived suppressor cells (MDSC) and regulatory T
119 Prominent among immunosuppressive cells are myeloid-derived suppressor cells (MDSC) and tumor-associ
133 hepatic stellate cells allowed generation of myeloid-derived suppressor cells (MDSC) from precursors
134 r, its role in the expansion and function of myeloid-derived suppressor cells (MDSC) has not been det
136 )) and monocytic (CD11b(+)Ly6G(-)Ly6C(high)) myeloid-derived suppressor cells (MDSC) in chronically i
138 in marked contrast, it reduced the levels of myeloid-derived suppressor cells (MDSC) in mice bearing
139 triggers robust induction of CD11b(+)Gr-1(+) myeloid-derived suppressor cells (MDSC) in the peritoneu
141 f melanoma is associated with restoration of myeloid-derived suppressor cells (MDSC) in the tumor mic
143 arrier to efficacy may be the recruitment of myeloid-derived suppressor cells (MDSC) into the tumor m
150 static liver tissue recruited CXCR2-positive myeloid-derived suppressor cells (MDSC) to form a premet
151 he G-CSF-driven mobilization of granulocytic myeloid-derived suppressor cells (MDSC) to the breast ca
152 8(+) T cells, regulatory T cells (Treg), and myeloid-derived suppressor cells (MDSC) were profiled by
153 ) delivery of paclitaxel to tumor-associated myeloid-derived suppressor cells (MDSC), (ii) MPO-regula
154 ing in hematopoietic progenitor cells (HPC), myeloid-derived suppressor cells (MDSC), and dendritic c
155 g tumor formation, including FoxP3(+) Tregs, myeloid-derived suppressor cells (MDSC), and M2 macropha
156 mice, increased immunosuppressive cytokines, myeloid-derived suppressor cells (MDSC), and regulatory
157 resistance to immune suppression mediated by myeloid-derived suppressor cells (MDSC), as derived from
158 icles (EV) convert normal myeloid cells into myeloid-derived suppressor cells (MDSC), inhibiting anti
161 ruiting regulatory T cells (Treg) and innate myeloid-derived suppressor cells (MDSC), which facilitat
168 has been reported to induce the expansion of myeloid-derived suppressor cells (MDSC); however, little
169 a, IL-5) and suppressive immune populations (myeloid-derived suppressor cells; MDSC) compared to cont
170 nd simultaneously decrease the population of myeloid derived suppressor cells (MDSCs) within the tumo
173 KDR expression increased in myeloid cells as myeloid-derived suppressor cells (MDSCs) accumulated, wh
176 ffector T cell tumor infiltration, decreased myeloid-derived suppressor cells (MDSCs) and further dec
177 expansion of inflammatory cells that include myeloid-derived suppressor cells (MDSCs) and IL-13(+) Th
178 secretome to drive monocyte polarization to myeloid-derived suppressor cells (MDSCs) and M2-like mac
179 studied the regulatory mechanism mediated by myeloid-derived suppressor cells (MDSCs) and showed that
180 opulation that was phenotypically similar to myeloid-derived suppressor cells (MDSCs) and that suppre
181 ed the infiltration of myeloid cells such as myeloid-derived suppressor cells (MDSCs) and tumor-assoc
187 y contributes to cancer metastasis, in which myeloid-derived suppressor cells (MDSCs) are an importan
199 s an immunosuppressive microenvironment with myeloid-derived suppressor cells (MDSCs) as a dominant p
200 me to the forefront in cancer research, with myeloid-derived suppressor cells (MDSCs) as a main oncol
201 gher CD8(+) T cells and fewer Gr1(+)CD11b(+) myeloid-derived suppressor cells (MDSCs) at early time p
202 mote the differentiation and accumulation of myeloid-derived suppressor cells (MDSCs) both in vitro a
207 this study, we investigated the response of myeloid-derived suppressor cells (MDSCs) during the path
210 ced by tumors, neutrophils, and granulocytic myeloid-derived suppressor cells (MDSCs) from cancer pat
211 stellate cells induce the differentiation of myeloid-derived suppressor cells (MDSCs) from myeloid pr
216 pase (LAL) deficiency causes infiltration of myeloid-derived suppressor cells (MDSCs) in multiple org
217 We recently identified a critical role for myeloid-derived suppressor cells (MDSCs) in S. aureus bi
220 of Blood, Hou et al show the involvement of myeloid-derived suppressor cells (MDSCs) in the pathogen
221 i.p. to TCDD showed massive mobilization of myeloid-derived suppressor cells (MDSCs) in the peritone
222 lammasome pathway influences the function of myeloid-derived suppressor cells (MDSCs) in the setting
225 dition to their immune-suppressive activity, myeloid-derived suppressor cells (MDSCs) influence tumor
227 cell responses in tumor microenvironments by myeloid-derived suppressor cells (MDSCs) is widely accep
228 ry Th1 and Th17 cells, accumulation of donor myeloid-derived suppressor cells (MDSCs) mediated by ILC
229 el, we show an expansion of Gr-1(+) CD11b(+) myeloid-derived suppressor cells (MDSCs) occurring intra
233 of a population of cells with similarity to myeloid-derived suppressor cells (MDSCs) that may have s
234 ased proportion of immunosuppressive CD33(+) myeloid-derived suppressor cells (MDSCs) that negatively
236 ited CD11b(+)Gr-1(high)Ly-6C(+) granulocytic myeloid-derived suppressor cells (MDSCs) to the liver of
237 1(low)CD11c(+) MDCs and Gr-1(high)CD11c(neg) myeloid-derived suppressor cells (MDSCs) were enriched i
240 WT, but not IFNAR-deficient mice, monocytic myeloid-derived suppressor cells (MDSCs) were recruited
241 We and others have previously shown that myeloid-derived suppressor cells (MDSCs), a heterogeneou
243 ue-resident memory (TRM) CD8+ T lymphocytes, myeloid-derived suppressor cells (MDSCs), and alternativ
244 Recently, a novel subset of innate cells, myeloid-derived suppressor cells (MDSCs), has been descr
246 ally and functionally resemble tumor-induced myeloid-derived suppressor cells (MDSCs), indicating an
248 Regulatory myeloid immune cells, such as myeloid-derived suppressor cells (MDSCs), populate infla
250 ry hematopoiesis and massive accumulation of myeloid-derived suppressor cells (MDSCs), which actively
251 ns induces a distinct subset of neutrophilic myeloid-derived suppressor cells (MDSCs), which function
252 d for mutants that failed to induce IL-10 in myeloid-derived suppressor cells (MDSCs), which identifi
253 the local accumulation of tumor-infiltrating myeloid-derived suppressor cells (MDSCs), which suppress
264 cells that infiltrated from the circulation (myeloid-derived suppressor cells [MDSCs], monocyte-deriv
266 +; 95% CI, 1.13-8.35; P = .01) and monocytic myeloid derived suppressor cells (mMDSC) (95% CI, 3.62-1
268 gates cytokine-driven expansion of monocytic myeloid-derived suppressor cells (mMDSC) from human or m
269 et al. report increased numbers of monocytic myeloid-derived suppressor cells (Mo-MDSC) in psoriasis
270 Recently, CD14(+) HLA-DR(-/low) monocytic myeloid-derived suppressor cells (Mo-MDSCs) have been sh
272 ells, dendritic cells, natural killer cells, myeloid-derived suppressor cells, neutrophils, or macrop
274 sed production of inflammatory cytokines and myeloid-derived suppressor cells occurs in patients with
275 In contrast to tumor-associated macrophages, myeloid-derived suppressor cells, or inflammatory monocy
276 ory T cells (Tregs) (ie, ICOShigh/PD-1-) and myeloid-derived suppressor cells (PD-1low) are expanded
278 ately led to the recruitment of granulocytic myeloid-derived suppressor cells (PMN-MDSCs) into tumor
279 natural killer (NK) cells, polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs), mononuclea
281 addition, old mice demonstrated expansion of myeloid-derived suppressor cell populations and sustaine
284 did not significantly modulate intratumoral myeloid-derived suppressor cells quantitatively, but dim
285 angiogenic switching appears to be caused by myeloid-derived suppressor cells recruited to the premet
286 ine profiles and high levels of granulocytic myeloid-derived suppressor cells resulted in loss of imm
287 ssion of numerous immune factors involved in myeloid-derived suppressor cell survival and trafficking
288 sponses and instead favored the induction of myeloid-derived suppressor cells, the immune-suppressive
289 y mediating the recruitment of monocytes and myeloid-derived suppressor cells to the tumor microenvir
293 parable elevations of T-regulatory cells and myeloid-derived suppressor cells were observed in both r
294 n of reactive oxygen species in granulocytic myeloid-derived suppressor cells, whereas the antioxidan
295 ly sepsis deterioration and were enriched in myeloid-derived suppressor cells which could be responsi
297 ent include tumor-associated macrophages and myeloid-derived suppressor cells, which not only mediate
298 nd P38 MAPK signaling responses in monocytic myeloid-derived suppressor cells, which was paired with
299 otal content of effector T cells, Tregs, and myeloid-derived suppressor cells, while effector T cells
300 Further study revealed a subpopulation of myeloid-derived suppressor cells within the CD11b(+) Gr-