ライフサイエンスコーパス: myofibrillar

1 D1 myopathy with sarcomeric disorganization, myofibrillar aggregates, and marked swimming defect.

2 s myofibrillar vacuolization and plaque-like myofibrillar aggregation.

3 ous lobulated muscle fibres and considerable myofibrillar alterations with a coarse and irregular int

4 Proteomic analysis encompassed 38 myofibrillar and 46 soluble proteins and the rates of ch

5 Regulatory proteins, metabolic enzymes, some myofibrillar and blood plasma proteins were identified,

6 tions on Drosophila cardiac performance, rat myofibrillar and cardiomyocyte properties, and human TNT

7 wo protease extracts appeared to target meat myofibrillar and collagen proteins differently, suggesti

8 as found to be more effective at hydrolysing myofibrillar and collagen proteins than the asparagus pr

9 ions using fluorescent-labelled casein, meat myofibrillar and connective tissue extracts to explore t

10 indicate that HT protease hydrolysis of meat myofibrillar and connective tissue protein extracts prod

11 valuated for their ability to hydrolyse meat myofibrillar and connective tissue protein extracts to p

12 ime course hydrolysis over 120 and 60 min of myofibrillar and connective tissue proteins, respectivel

13 g of multiple genes including those encoding myofibrillar and cytoskeletal proteins, and proteins tha

14 alone, and this was accompanied by elevated myofibrillar and cytosolic protein as well as DNA synthe

15 Massage enhances protein synthesis of the myofibrillar and cytosolic, but not the mitochondrial fr

16 nd water molecules, and distribution between myofibrillar and extra-myofibrillar compartments.

17 ients with CHF and stimulate skeletal muscle myofibrillar and mitochondrial adaptations.

18 le biopsy samples were obtained to determine myofibrillar and mitochondrial MPS and the phosphorylati

19 We hypothesized that rates of myofibrillar and patellar tendon collagen synthesis woul

20 uce a decrease in protein solubility in both myofibrillar and sarcoplasmic fractions.

21 thesis rates of mixed muscle protein and the myofibrillar and sarcoplasmic muscle fractions.

22 To investigate this, we assessed myofibrillar and sarcoplasmic protein synthesis (MPS, SP

23 monstrate that several peptides derived from myofibrillar and sarcoplasmic proteins are sufficiently

24 This study investigated denaturation of myofibrillar and sarcoplasmic proteins of pork loins cau

25 Considerable differences in abundance of myofibrillar and sarcoplasmic proteins were observed bet

26 nificant correlation with higher contents of myofibrillar and sarcoplasmic proteins, smaller muscle f

27 egradation for a total of five non-redundant myofibrillar and sarcoplasmic proteins.

28 In total, 18 differentially abundant myofibrillar and sarcoplasmic proteins/isoforms contribu

29 Thus, both myofibrillar and tendon protein synthetic rates show pro

30 s the lateral sarcomere lattice and distorts myofibrillar angular axial orientation.

31 rmediate filaments interlink the contractile myofibrillar apparatus with mitochondria, nuclei, and th

32 gates and a concurrent disarrangement of the myofibrillar apparatus.

33 ly hearts for the maintenance of both normal myofibrillar architecture and cardiac physiology.

34 lying the cascade of events that destroy the myofibrillar architecture and trigger the aberrant expre

35 xhibited impaired cardiac output and altered myofibrillar architecture, and adult heart-specific inte

36 signal that potentiates the organization of myofibrillar arrays in cardiac muscle myocytes.

37 and heterozygotes showed normal morphology, myofibrillar arrays, and contractile parameters.

38 ha-MyHC), with the net outcome of diminished myofibrillar ATPase activity and impaired contractility.

39 Measurements of myofibrillar ATPase activity in the absence of Ca(2+) sh

40 on to carbohydrate stimulates an increase in myofibrillar, but not mitochondrial, MPS following prolo

41 eletal muscle troponin, leading to increased myofibrillar Ca(2)(+) sensitivity in fast skeletal muscl

42 activator (FSTA) CK-2066260, which increases myofibrillar Ca(2+) sensitivity and amplifies the submax

43 Robot 2.0 by assessing temperature-dependent myofibrillar Ca(2+) sensitivity, passive axial complianc

44 ctility that could be explained by increased myofibrillar Ca(2+) sensitivity.

45 troponin Ca(2+) affinity, thereby increasing myofibrillar Ca(2+) sensitivity.

46 gnals via its cognate receptor SUCNR1 in non-myofibrillar cells in muscle tissue to control muscle-re

47 exchange rate between them, diameter of the myofibrillar cells.

48 g human heart, offering direct evidence that myofibrillar CK energy delivery can be pharmaceutically

49 distribution between myofibrillar and extra-myofibrillar compartments.

50 blood by rapidly disassembling and reforming myofibrillar components of the sarcomere throughout cell

51 roteins in denervated muscle identified many myofibrillar components.

52 ss changes due to RNA interference to reduce myofibrillar content or due to aging in Drosophila myoca

53 We demonstrate that mutant desmin alters myofibrillar cytoarchitecture, markedly disrupts the lat

54 S6K, suppressed the held-up wing phenotype, myofibrillar defects and LamC aggregation.

55 of Mef2A knock-out mice has revealed severe myofibrillar defects in cardiac muscle indicating a requ

56 ype LamC, caused held-up wings indicative of myofibrillar defects.

57 Increased oxidative stress could cause myofibrillar degeneration and lipofuscin accumulation re

58 uscle isolated from bag3(-/-) mice exhibited myofibrillar degeneration and lost contractile activity

59 use mutant that suffers from skeletal muscle myofibrillar degeneration due to the rapid accumulation

60 phosphorylation and prevented cardiomyocyte myofibrillar degeneration in MR dogs.

61 abilizing myofibril structure and inhibiting myofibrillar degeneration in response to mechanical stre

62 LV biopsies demonstrated cardiomyocyte myofibrillar degeneration versus normal subjects (p = 0.

63 utation carriers showed sarcomeric disarray, myofibrillar degeneration, and increased apoptosis, whil

64 ignificantly reduced FA protein degradation, myofibrillar degeneration, and myocyte apoptosis induced

65 termine the molecular trigger of upheld(101) myofibrillar degeneration, to evaluate contractile perfo

66 hy, characterized by protein aggregation and myofibrillar degeneration.

67 skeletal muscle Z-discs and accumulation of myofibrillar degradation products.

68 about 1 per 400 alpha-actinin) important for myofibrillar development and mechanotransduction.

69 Electron microscopy revealed myofibrillar disarray and degeneration with hyaline-like

70 had development of cardiac hypertrophy with myofibrillar disarray and fibrosis, in addition to activ

71 art examined by electron microscopy revealed myofibrillar disarray and mild fibrosis.

72 aracterized by left ventricular hypertrophy, myofibrillar disarray and sudden cardiac death.

73 cells exhibit reduced contractile force and myofibrillar disarray despite the presence of full-lengt

74 as the mechanistic basis of the progressive myofibrillar disarray observed in the Drosophila models

75 tricular (LV) mass, contractile dysfunction, myofibrillar disarray, and fibrosis.

76 t extracellular regulated kinase 1/2, causes myofibrillar disarray, whereas the enlarged cardiomyocyt

77 cal mdx muscle is found to be a signature of myofibrillar disorder.

78 and DNAJB6b-F93L expressing mouse muscle had myofibrillar disorganization and desmin inclusions.

79 ns, nuclear and mitochondrial dysmorphology, myofibrillar disorganization and up-regulation of the au

80 ce contained 'cores' characterized by severe myofibrillar disorganization associated with misplacemen

81 sly abnormal skeletal muscle development and myofibrillar disorganization at the microscopic level.

82 stion of whether bag3 gene knockdown induces myofibrillar disorganization caused by mechanical stress

83 thology showed abundant internalized nuclei, myofibrillar disorganization, desmin-positive inclusions

84 ults in highly diminished motor function and myofibrillar disorganization, with nemaline body formati

85 ssembly in the heterozygous state but caused myofibrillar disruption during aging.

86 r hand, overexpression of CapZbeta1 inhibits myofibrillar disruption in bag3 knockdown cells under me

87 tease assays with connective tissue and meat myofibrillar extracts provide a more realistic evaluatio

88 t in both beef connective tissue and topside myofibrillar extracts.

89 tochondrial distribution and function; (iii) myofibrillar force generation; (iv) atrophy; and (v) aut

90 for efficient energy production, whereas the myofibrillar fraction had important contractile proteins

91 sectional area and protein synthesis of the myofibrillar fraction, but not DNA synthesis, are elevat

92 led a significant decrease of R448H from the myofibrillar fraction, likely due to the mutant's inabil

93 e carboxymethylation and localization to the myofibrillar fraction, of the catalytic subunit of prote

94 Muscles have a reduced myofibrillar fractional-area and sarcomeres are disorgan

95 radicals were formed in the sarcoplasmic and myofibrillar fractions as well as in the non-soluble pro

96 efficiently fractionated to sarcoplasmic and myofibrillar fractions, prior to the identification base

97 Irradiation negatively affected myofibrillar fragmentation, but samples irradiated at 9

98 Oxidants depress myofibrillar function, decreasing specific force without

99 of myocardin/serum response factor-regulated myofibrillar genes is extinguished, or profoundly attenu

100 tion of YY1 and transcriptional silencing of myofibrillar genes represent a new mechanism by which NF

101 B caused the pronounced induction of several myofibrillar genes, suggesting that NF-kappaB functions

102 erozygous mice developed muscle weakness and myofibrillar instability, with formation of filamin C- a

103 ltered sarcomeric actin pattern, in affected myofibrillar integrity and in Z-band breaks, leading to

104 together, we demonstrate that CryAB ensures myofibrillar integrity in Drosophila muscles during deve

105 ruption in ordered myofibrillogenesis and/or myofibrillar integrity, and the consequent myosin aggreg

106 erated mice conditionally overexpressing the myofibrillar isoform of CK (CK-M) to test the hypothesis

107 , thick and thin filaments are arranged in a myofibrillar lattice.

108 d impaired electromechanical coupling at the myofibrillar level.

109 Myofibrillar lipid and protein oxidation increased with

110 ved matrikines, accompanied by cardiomyocyte myofibrillar loss and apoptosis, and by enhanced macroph

111 Moreover, we show that the myofibrillar matrix is united across the entire width of

112 that striated muscle cells form a continuous myofibrillar matrix linked together by frequently branch

113 ering calcium regulation or other aspects of myofibrillar mechanics.

114 situ cardiac systolic mechanics and in vitro myofibrillar mechanics.

115 ULLS induced a reduction of myofibrillar, metabolic (glycolytic and oxidative) and a

116 AS/HNO did not alter myofibrillar Mg-ATPase activity, supporting an effect on

117 this novel line, we compiled a reference for myofibrillar microarchitecture among myocardial subtypes

118 rcise induces a gene signature that includes myofibrillar, mitochondrial and oxidative lipid metaboli

119 Myofibrillar MPS (mean +/- SD) increased (P < 0.05) abov

120 Postabsorptive rates of myofibrillar MPS and whole-body rates of phenylalanine o

121 imilarly with endurance and RE, increases in myofibrillar MPS are specific to RE, prophetic of adapta

122 These data indicate that the increase in myofibrillar MPS for C+P could, potentially, be mediated

123 ximal stimulation of postabsorptive rates of myofibrillar MPS in rested and exercised muscle of ~80-k

124 response relation of postabsorptive rates of myofibrillar MPS to increasing amounts of whey protein a

125 Myofibrillar MPS was approximately 35% greater for C+P c

126 ent study was to determine mitochondrial and myofibrillar muscle protein synthesis (MPS) when carbohy

127 Myofibrillar myopathies (MFMs) are morphologically disti

128 alignment of Z-disks, which are hallmarks of myofibrillar myopathies (MFMs).

129 tion is to provide an up-to-date overview of myofibrillar myopathies (MFMs).

130 The most important recent advance in the myofibrillar myopathies has been the discovery that muta

131 FLNC mutations have been associated with myofibrillar myopathies, and cardiac involvement has bee

132 resence of proteins typically found in human myofibrillar myopathies, suggesting that the genesis of

133 sease genes have recently been recognized in myofibrillar myopathies.

134 tion is to provide an up-to-date overview of myofibrillar myopathies.

135 aggregates, the main pathological symptom of myofibrillar myopathies.

136 re and function at pre-symptomatic stages of myofibrillar myopathies.

137 Desmin-related myofibrillar myopathy (DRM) is a cardiac and skeletal mu

138 (ACTA1), tubular aggregate myopathy (STIM1), myofibrillar myopathy (FLNC), and mutation of CHD7, usua

139 Filamin C (FLNC) mutations in humans cause myofibrillar myopathy (MFM) and cardiomyopathy, characte

140 mutation results in a severe childhood-onset myofibrillar myopathy (MFM) associated with progressive

141 Desmin-associated myofibrillar myopathy (MFM) has pathologic similarities

142 he original patients had features resembling myofibrillar myopathy (MFM), arguing that TTN mutations

143 -like motif that is mutated in zaspopathy, a myofibrillar myopathy (MFM), whereas the exon 8-11 junct

144 d "protein conformational diseases," such as myofibrillar myopathy and familial amyotrophic lateral s

145 , have indicated that patients affected with myofibrillar myopathy have a more distal than proximal m

146 ese results, we suggest that p.D399Y-related myofibrillar myopathy is at least partly due to altered

147 r further research to identify therapies for myofibrillar myopathy or other degenerative diseases.

148 ) family proteins, causes cardiomyopathy and myofibrillar myopathy that is characterized by myofibril

149 R120G mutated form of HspB5 (associated with myofibrillar myopathy), or expression of the G985R and G

150 In every myofibrillar myopathy, there is abnormal accumulation of

151 genital myopathies that include nemaline and myofibrillar myopathy.

152 tions in skeletal muscle that are typical of myofibrillar myopathy.

153 body protein metabolism, and skeletal muscle myofibrillar (MyoPS) and mitochondrial (MitoPS) protein

154 ycin complex 1 (mTORC1) in the regulation of myofibrillar (MyoPS) and mitochondrial (MitoPS) protein

155 l lower-limb immobilization, and the role of myofibrillar (MyoPS) and mitochondrial (MitoPS) protein

156 force is generated by a singular, mesh-like myofibrillar network rather than many individual, parall

157 This is in contrast with the myofibrillar network, which displayed the same organizat

158 at all muscle cells contain highly connected myofibrillar networks though the frequency of sarcomere

159 mic proteins were hydrolyzed faster than the myofibrillar ones by both human/porcine enzymes.

160 nvestigate the effects of Erbb2 signaling on myofibrillar organization because drugs targeting ERBB2

161 in, and alpha-actinin and a complete loss of myofibrillar organization in fast-twitch muscles.

162 ltured on rigid surfaces exhibited increased myofibrillar organization, spread morphology, and reduce

163 viously unknown conserved role of UNC-45B in myofibrillar organization.

164 ular matrix may be an important regulator of myofibrillar organization.

165 MFM patients, these mice develop progressive myofibrillar pathology that includes Z-disc streaming, e

166 ch-like and fast-twitch-like by PKA-mediated myofibrillar phosphorylation, which implicates a novel m

167 ependent upon protein kinase A (PKA)-induced myofibrillar phosphorylation.

168 es correlates with a significant decrease in myofibrillar PKA activity.

169 Although several myofibrillar promoters contain predicted NF-kappaB bindi

170 more, YY1 was found associated with multiple myofibrillar promoters in C2C12 myoblasts containing NF-

171 inoleic acid; liposome; emulsion) containing myofibrillar protein (MFP at 1, 8 and 20mg/mL) under hyd

172 e chemical structure and gelling behavior of myofibrillar protein (MP) was investigated.

173 ne required for myogenic differentiation and myofibrillar protein assembly in vertebrates.

174 Morpholino knockdown resulted in defects in myofibrillar protein assembly, particularly in slow musc

175 ng of myofibrils and hence did not reproduce myofibrillar protein changes in freezing.

176 s as an integrator of Ca(2+) homeostasis and myofibrillar protein content during stress in the heart

177 rt failure patients due, in part, to loss of myofibrillar protein content, in particular myosin.

178 calpain activity, markedly attenuated FA and myofibrillar protein degradation induced by Cat.G.

179 in activity, which subsequently affected the myofibrillar protein degradation pattern in pork meat.

180 water of frozen meat is the primary cause of myofibrillar protein denaturation in frozen-thawed meat.

181 increased surface hydrophobicity, suggesting myofibrillar protein denaturation occurred by a comparab

182 Cardiac troponin T (cTnT) is a myofibrillar protein essential for calcium-dependent con

183 Paramyosin, a myofibrillar protein found only in invertebrates, has be

184 impairs contractile performance by altering myofibrillar protein function.

185 The in vitro myofibrillar protein hydrolysate showed the highest ABTS

186 ffect of the two AA isoforms on collagen and myofibrillar protein hydrolyzing activity varied dependi

187 Reduction of MbFe(IV)O by a myofibrillar protein isolate (MPI) from pork resulted in

188 Myofibrillar protein profiles confirmed fiber type diffe

189 Rheological attributes of myofibrillar protein solutions during thermal gelation a

190 uitin ligase activity, is involved in FA and myofibrillar protein stability and turnover in myocytes.

191 Whole body and leg glucose disposal, muscle myofibrillar protein synthesis (MPS) and leg protein bre

192 We investigated how myofibrillar protein synthesis (MPS) and muscle anabolic

193 ure of branched chain amino acids (BCAAs) on myofibrillar protein synthesis (MPS) at rest and after e

194 cronutrient meals on integrated 3-d rates of myofibrillar protein synthesis (MyoPS) in free-living ol

195 nemia-hyperaminoacidemia-induced increase in myofibrillar protein synthesis (percentage increase from

196 We have focused on pathways controlling myofibrillar protein synthesis and degradation, mitochon

197 in young men, with a stronger stimulation of myofibrillar protein synthesis during the early postpran

198 Rates of myofibrillar protein synthesis fell (P < 0.01) from 0.04

199 min after oral protein bolus, mean (+/- SEM) myofibrillar protein synthesis increased from 0.03 +/- 0

200 BCAA, and BCKA significantly increased early myofibrillar protein synthesis rates (0-2 h) above basal

201 t D + CLA supplementation affected the basal myofibrillar protein synthesis rates (placebo: 0.040 +/-

202 yperinsulinemia-hyperaminoacidemia increased myofibrillar protein synthesis rates by ~35%.

203 However, the increase in myofibrillar protein synthesis rates did not differ betw

204 6 g BCAA, 6 g BCKA, and 30 g MILK increases myofibrillar protein synthesis rates during the early po

205 Myofibrillar protein synthesis rates during the late pos

206 ing amino acid concentrations and subsequent myofibrillar protein synthesis rates in older males.

207 lability, anabolic signaling, and subsequent myofibrillar protein synthesis rates in vivo in young me

208 g BCAA and BCKA is short-lived, with higher myofibrillar protein synthesis rates only being maintain

209 Milk ingestion increased myofibrillar protein synthesis rates to a greater extent

210 Basal and postprandial myofibrillar protein synthesis rates were assessed by pr

211 Myofibrillar protein synthesis rates were evaluated by u

212 Before the intervention, basal myofibrillar protein synthesis rates were not different

213 +/- 0.003% to 0.10 +/- 0.01%/h; thereafter, myofibrillar protein synthesis returned to baseline rate

214 exercise resulted in greater stimulation of myofibrillar protein synthesis than did the ingestion of

215 fibre size compared to reloading alone, and myofibrillar protein synthesis, but not DNA synthesis, w

216 id transporters (LAT1, SNAT2) and CD98], and myofibrillar protein synthesis.

217 ucine kinetics, intramuscular signaling, and myofibrillar protein synthesis.Plasma appearance rates o

218 lity, anabolic signaling, and the subsequent myofibrillar protein synthetic response after the ingest

219 We compared the myofibrillar protein synthetic response and underlying n

220 and beef ingestion augment the postexercise myofibrillar protein synthetic response in young men, wi

221 ese data indicate that impaired postprandial myofibrillar protein synthetic response may be an early

222 ole-egg ingestion increased the postexercise myofibrillar protein synthetic response to a greater ext

223 There is a diminished myofibrillar protein synthetic response to the ingestion

224 However, myofibrillar protein synthetic responses (0-300 min) wer

225 Basal myofibrillar protein synthetic responses were similar be

226 Obscurin is a large myofibrillar protein that contains several interacting m

227 dditives is mainly based on the induction of myofibrillar protein unfolding thus facilitating the for

228 of allysine in beta-lactoglubulin (LAC), and myofibrillar proteins (MP) (2 mg/mL) during incubation a

229 ion pathway occurred during the oxidation of myofibrillar proteins (MP) catalysed by a Fe(3+)/H2O2 sy

230 eins were mostly of muscle origin: including myofibrillar proteins (titin, myosin light chain 1/3, my

231 several groups of proteins among which were myofibrillar proteins and antioxidant defence systems; (

232 strate-trap) became associated with specific myofibrillar proteins and its cofactors, Ufd1 and p47, a

233 ionation step to deplete the highly abundant myofibrillar proteins and performed a second phosphoprot

234 regulation attenuated the loss of desmin and myofibrillar proteins and reduced atrophy.

235 meat affected the water binding sites of the myofibrillar proteins and, thereby, the interactions bet

236 During muscle atrophy, myofibrillar proteins are degraded in an ordered process

237 Several membrane and myofibrillar proteins are phosphorylated under these con

238 e distribution, protein interaction with key myofibrillar proteins as well as the conformation mallea

239 equent myofibril destruction, and over time, myofibrillar proteins become more susceptible to PAX4-in

240 phenolics on the oxidative damage caused to myofibrillar proteins by an in vitro metal-catalyzed oxi

241 Digestibility of myofibrillar proteins by pepsin was determined by in vit

242 Protein kinase A (PKA) phosphorylation of myofibrillar proteins constitutes an important pathway f

243 p97 participates to the rapid degradation of myofibrillar proteins during muscle atrophy.

244 us proteases, responsible for proteolysis of myofibrillar proteins during post-mortem storage, may be

245 ic sites as well as accumulation of degraded myofibrillar proteins forming large aggregates.

246 Myofibrillar proteins from alpha-white fibres were more

247 strength (mu) on the extraction capacity of myofibrillar proteins from Jumbo squid mantle muscle alo

248 nvestigates the susceptibility of individual myofibrillar proteins from mackerel (Scomber scombrus) m

249 re-induced modification and functionality of myofibrillar proteins from pork meat pressurised at 200,

250 logy of IFN-gamma exposure and its effect on myofibrillar proteins in isolated neonatal rat ventricul

251 yme modulates the expression of myogenin and myofibrillar proteins in L6 muscle cells.

252 results predict that PKA phosphorylation of myofibrillar proteins in living myocardium contributes t

253 indicate that the phosphorylation pattern of myofibrillar proteins in PM muscle is mainly changed wit

254 A total of 656 peptides derived from major myofibrillar proteins in Protected Designation of Origin

255 zin) and an apple peel extract were added to myofibrillar proteins in three concentrations (50, 100 a

256 M) changes in protein phosphorylation of the myofibrillar proteins in three groups of pigs with diffe

257 d selective hydrolytic activity towards meat myofibrillar proteins including myosin and actin.

258 Loss of myofibrillar proteins is a hallmark of atrophying muscle

259 line, suggesting that the phosphorylation of myofibrillar proteins may be related to the meat rigor m

260 scle atrophy is the excessive degradation of myofibrillar proteins primarily by the ubiquitin proteas

261 of Frigate mackerel had greater contents of myofibrillar proteins than had catfish muscle (p<0.05).

262 t is assumed to be heated homogeneously, and myofibrillar proteins to be directly in contact with pep

263 In dry fermented sausages, myofibrillar proteins undergo intense proteolysis genera

264 roteomic approach involved the separation of myofibrillar proteins using OFFGEL electrophoresis, SDS-

265 tion factors, ion channels, and cytoskeletal/myofibrillar proteins was downregulated consequent to lo

266 The peptide HL from myofibrillar proteins was identified only in the ex vivo

267 -PAGE) indicated that the integrity of major myofibrillar proteins was maintained during the extracti

268 Myofibrillar proteins were observed as the major fractio

269 iaphragm lysates and the abundance of select myofibrillar proteins were unchanged by PH.

270 basic model made of an aqueous suspension of myofibrillar proteins, and a complex model, in which oxi

271 on as well as the expression of myogenin and myofibrillar proteins, and these effects were also depen

272 xidant activity against protein oxidation in myofibrillar proteins, emphasizing the potential of appl

273 ler myofiber size, decreased mRNA levels for myofibrillar proteins, increased proteolytic enzyme acti

274 in carbonylation and tryptophan depletion in myofibrillar proteins, ovalbumin, beta-lactoglobulin, so

275 th a negative impact on the digestibility of myofibrillar proteins.

276 that did not correspond to any of the major myofibrillar proteins.

277 s released during post-mortem proteolysis of myofibrillar proteins.

278 il, suggesting their interaction with surimi myofibrillar proteins.

279 has been involved in the degradation of bulk myofibrillar proteins.

280 < 0.05) than pH on the extraction of muscle myofibrillar proteins.

281 , indicating more pronounced denaturation of myofibrillar proteins.

282 ntifications were present on highly abundant myofibrillar proteins.

283 onths), focusing on those derived from major myofibrillar proteins.

284 ed an increased expression of genes encoding myofibrillar proteins.

285 alysing distinct subcellular fractions (e.g. myofibrillar, sarcoplasmic, mitochondrial) may provide a

286 The compartment model corresponds to the myofibrillar space (MS) and a calcium store, the sarcopl

287 ise in calcium (Ca(2+)) concentration in the myofibrillar space.

288 We observed a progressive decline in myofibrillar structural integrity (underpinning meat ten

289 lidation, we found that two fragments of the myofibrillar structural protein myomesin-3 (MYOM3) are a

290 tion that can adversely affect cardiomyocyte myofibrillar structure and function.

291 The mechanism by which myofibrillar structure is maintained under mechanical st

292 rsal vessels characterized by a disorganized myofibrillar structure, reduced systolic and diastolic d

293 f contractility may arise from alteration of myofibrillar structure.

294 Because PKA has multiple myofibrillar substrates including titin, myosin-binding

295 d in physiological Ca(2+) handling of the SR-myofibrillar system.

296 Notably, Ca(2)(+)-sensitivity and passive myofibrillar tension were decreased in heterozygous fibe

297 brosis and abnormal mitochondrial but normal myofibrillar ultrastructure.

298 ology that includes Z-disc streaming, excess myofibrillar vacuolization and plaque-like myofibrillar

299 and diffusion coefficient of intra and extra myofibrillar water populations, exchange rate between th

300 lamin influences the mechanical stability of myofibrillar Z-discs, explaining the muscle weakness in

301 lin, potentially attaching the sarcolemma to myofibrillar Z-lines.