ライフサイエンスコーパス: myosin heavy chain

1 s (GRK2, atrial natriuretic factor, and beta-myosin heavy chain).

2 fferentiation markers myogenin and embryonic myosin heavy chain.

3 s such as atrial natriuretic factor and beta-myosin heavy chain.

4 protein HSP90, one (putative) HSP70, and the myosin heavy chain.

5 factor, brain natriuretic peptide, and beta-myosin heavy chain.

6 enesis by stimulating the expression of slow myosin heavy chain.

7 inase (cMLCK), located at the neck region of myosin heavy chain.

8 smooth muscle alpha-actin and smooth muscle myosin heavy chain.

9 with actin and its C-terminal lobe with the myosin heavy chain.

10 and by performing immunostaining of neonatal myosin heavy chain.

11 olabelling muscle biopsies for developmental myosin heavy chain.

12 arboring heterozygous human mutations in the myosin heavy chain.

13 osine triphosphatase activity of the cardiac myosin heavy chain.

14 bers, which expressed an immature pattern of myosin heavy chains.

15 n-2 slow and troponin T and carbonylation of myosin heavy chains.

16 Myosin heavy chain 1 (MYH1), myosin heavy chain 2 (MYH2)

17 fibers, which express a slow fiber-specific myosin heavy chain 1 (Smyhc1), are the first group of mu

18 Brg1 also supports Myosin heavy chain 11 (Myh11) expression to allow NCCs t

19 sease-causing mutations in at least 4 genes: myosin heavy chain 11 (MYH11), alpha-smooth muscle actin

20 methylation status of the pivotal VSMC gene myosin heavy chain 11 (Myh11).

21 s markers such as alpha smooth muscle actin, myosin heavy chain 11, and smooth muscle 22 alpha.

22 Myosin heavy chain 1 (MYH1), myosin heavy chain 2 (MYH2), and myosin heavy chain 7 (M

23 n and terminal differentiation (myogenin and myosin heavy chain 2) were increased on d 2 and 4 postin

24 ct CPAs expressed h-caldesmon and non-muscle myosin heavy chain-2; phenotypic markers of contractile

25 myosin heavy chain genes suggests that human myosin heavy chain 3 is the functional homologue of the

26 markers MyoD, myogenin and embryonic myosin (myosin heavy chain 3, MYH3).

27 (SOX2), GATA binding protein 4 (GATA4), and myosin heavy chain 6 (MYH6).

28 and serum levels of ANP fell sharply in PAM myosin heavy chain 6 conditional knockout mice, and RNA

29 iquitination and UPS-mediated degradation of myosin heavy chain 6, cardiac myosin binding protein C,

30 ernal and maternal alleles of MYH6, encoding myosin heavy chain 6, in 2 patients who developed right

31 ntractile proteins (myosin light chain MLY2, myosin heavy chain 6, myosin-binding protein C), glucose

32 vation domains under the control of the Myh (myosin heavy chain) 6 promoter was generated.

33 n 1 (MYH1), myosin heavy chain 2 (MYH2), and myosin heavy chain 7 (MYH7) were distributed broadly acr

34 by increased myoglobin, slow twitch markers [myosin heavy chain 7 (MyH7), succinate dehydrogenase, tr

35 s undergo antisense transcription, including myosin heavy chain 7 (Myh7), which encodes molecular mot

36 In parallel, mRNA expression of myosin heavy chain 7 and natriuretic peptide B is up-reg

37 Elevated myosin heavy chain 7 mRNA expression is detected in left

38 ense variants in the MYH7-encoded MYH7 (beta myosin heavy chain 7) represent a leading cause of hyper

39 Thirteen variants in MYBPC3 and MYH7 (myosin heavy chain 7) were each identified >3 times and

40 ants, upheld(1) (up(1)), heldup(2) (hdp(2)), myosin heavy chain(7) (Mhc(7)), actin88F(KM88) (Act88F(K

41 pe 7; previously associated exclusively with myosin heavy chain 8 mutations).

42 ere we show the identification of non-muscle myosin heavy chain 9 (MYH9) as an essential factor for P

43 etected strong association between nonmuscle myosin heavy chain 9 gene (MYH9) variants on chromosome

44 suppresses TGF-beta-induced expression of SM myosin heavy chain, a late marker of SM differentiation.

45 ubb6 level correlates with that of embryonic myosin heavy chain, a regeneration marker.

46 use of a green fluorescent protein or a beta-myosin heavy chain adenovirus.

47 They showed that myosin heavy chain alpha (MYHCA) is a dominant cardiac a

48 class-II-restricted epitopes, we found that myosin heavy chain alpha (MYHCA) was a dominant cardiac

49 pulations expressing the structural proteins myosin heavy chain alpha and myosin light chain 2a in re

50 rdiomyocytes in mice primarily express alpha-myosin heavy chain (alpha-MHC, also known as Myh6), wher

51 se heart, which contains predominantly alpha-myosin heavy chain (alpha-MyHC), the applicability of th

52 -MyHC) and reduced expression of adult alpha-myosin heavy chain (alpha-MyHC), with the net outcome of

53 Here, we show that the alpha-isoform of myosin heavy chain (alpha-MyHC, which is encoded by the

54 intracellular cardiac antigens, like cardiac myosin heavy chain-alpha, cardiac troponin-I, and adenin

55 d the gene expression profiles between alpha-myosin heavy chain (alphaMHC)-BMP10 transgenic hearts an

56 ated cardiac-specific MDA5 transgenic (alpha-myosin heavy chain [alphaMHC]-MDA5) mice.

57 ice, CD4+ T cells specific for cardiac alpha myosin heavy chain (alphaMYHC) cause myocarditis and mic

58 rdiomyocytes that transiently express atrial myosin heavy chain (amhc) contributes substantially to s

59 As in the left ventricle, decrease in alpha-myosin heavy chain and a switch towards glycolysis from

60 Myosin heavy chain and actin were predominant proteins f

61 increased heart-to-body weight ratios, alpha myosin heavy chain and cardiac isoprostane levels, sugge

62 Patches of myosin heavy chain and dynamic furrowing of the plasma m

63 SMC phenotype with a marked reduction of SM-myosin heavy chain and increased proliferative capacity.

64 genes encoding the thick filament components myosin heavy chain and myosin binding protein C (MYH7 an

65 tic peptide, brain natriuretic peptide, beta-myosin heavy chain and myosin light chain (2- to 5-fold,

66 was seen in heart failure events between the myosin heavy chain and myosin-binding protein C genotype

67 h no differences in event rates seen between myosin heavy chain and myosin-binding protein C genotype

68 MYH7 and MYBPC3, encoding beta-myosin heavy chain and myosin-binding protein C, respect

69 tone marks and did not show up-regulation of myosin heavy chain and myotube formation when grown in d

70 Also, SOD1 myotubes had loosely arranged myosin heavy chain and reduced acetylcholine receptor ex

71 bres, revealing the absolute fast isoform of myosin heavy chain and the abundance of glycogen and mit

72 uscles, represented by the expression of the myosin heavy chain and the oxidative markers PGC1-alpha

73 structural proteins, such as alpha and beta myosin heavy chains and cardiac alpha actin, play crucia

74 ein that is homologous to the rod portion of myosin heavy chains and resides in thick filament cores.

75 actor, alpha-skeletal muscle actin, and beta-myosin heavy chain) and collagens were observed between

76 rtrophic cardiomyopathy (HCM) are MYH7 (beta-myosin heavy chain) and MYBPC3 (beta-myosin-binding prot

77 n of contraction-related genes, such as MYH (myosin heavy chain) and troponin I, consistent with its

78 muscle alpha-actin (SM actin), smooth muscle myosin heavy chain, and calponin1, and the expression of

79 the cardiac markers troponin I, troponin T, myosin heavy chain, and connexin-43.

80 A in polysomes, the levels of Mef2c and slow myosin heavy chain, and myofibril content.

81 nnexin 43, myosin light chain 2a, alpha/beta-myosin heavy chain, and troponin I.

82 increased myogenic markers such as Myogenin, myosin heavy chains, and myogenic differentiation 1 (Myo

83 being peptides derived from nebulin, titin, myosin heavy chains, and troponin I proteins, those show

84 LP-1 haplodeficiency in the transgenic alpha-myosin heavy chain-angiotensinogen mice causes prominent

85 tions in the MYH7 gene encoding for the beta-myosin heavy chain are the underlying genetic cause of M

86 Two myosin heavy chains are expressed in the myoepithelial s

87 , we studied mice carrying the HCM mutation, myosin heavy-chain Arg403Gln, (MHC(403/+)) and an Mef2-d

88 e perform lineage tracing with smooth muscle myosin heavy chain as a marker and find that multipotent

89 In mice, these transcripts, which we named myosin heavy-chain-associated RNA transcripts (Myheart,

90 ick filaments throughout the cell cycle, (2) myosin heavy chain-based control of myosin assembly at t

91 erozygous missense mutations in beta-cardiac myosin heavy chain (beta-MHC).

92 results in enhanced expression of fetal beta-myosin heavy chain (beta-MyHC) and reduced expression of

93 the R403Q mutation in the gene encoding beta-myosin heavy chain (beta-MyHC).

94 red into a mouse genetic model of CHF (alpha-myosin heavy chain-calsequestrin), MCK-EcSOD transgenic

95 s disrupted when modeling human beta-cardiac myosin heavy chain cardiomyopathy mutations E497D or R71

96 nd enhancer hub that regulates the essential myosin heavy chain cluster during skeletal muscle cell d

97 th heart defects, whereas deletion with beta-myosin heavy chain-cre (betaMHC-cre) produced viable adu

98 pecific LKB1 knock-out (KO) mice using alpha-myosin heavy chain-Cre deletor strain.

99 rdiac-specific ILK knockout mice using alpha-myosin heavy chain-driven Cre expression.

100 Myosin heavy chain-embryonic (MyHC-emb) is a skeletal mu

101 The expression and function of embryonic myosin heavy chain (eMYH) has not been investigated with

102 gless (Wg) signaling pathway and a nonmuscle myosin heavy chain, encoded by the crinkled (ck) locus i

103 a muscle phenotype with rapid expression of myosin heavy chain, even in proliferative conditions.

104 re binding factor beta and the smooth-muscle myosin heavy chain), expressed in AML with the chromosom

105 ine of evidence for the differentiated alpha-myosin heavy chain-expressing cardiomyocyte as the cell

106 atal regenerating muscle, but only in type I myosin heavy chain-expressing cells.

107 ellular reactive oxygen species (ROS), alpha-myosin heavy chain expression (alpha-MHC), and intracell

108 Embryonic myosin heavy chain expression and central nucleation, in

109 ed CTX injury-induced myogenin and embryonic myosin heavy chain expression and increased the size of

110 sgenic mice further exhibited decreased beta myosin heavy chain expression compared to age matched no

111 Fiber type (myosin heavy chain expression) and 2DG accumulation were

112 erexpression, on the other hand, enhances SM myosin heavy chain expression.

113 layed cardiac hypertrophy and increased beta myosin heavy chain expression.

114 entiation was confirmed by uniform NCAM1 and myosin heavy chain expression.

115 myosin heavy chain primers revealed that the myosin heavy-chain expression in fused cells was derived

116 The expression of tail-specific myosin heavy chain (fmyhc2.1) requires wnt signaling and

117 lpha) is a novel biomarker along with smooth myosin heavy chain for the pacemaker cells (previously t

118 of S100A4 in complex with a 45-residue-long myosin heavy chain fragment.

119 Mutations in the beta-cardiac myosin heavy chain gene (beta-MyHC) are a major cause of

120 ded within an intron of alpha-cardiac muscle myosin heavy chain gene (Myh6), was actually a member of

121 Variation in the human beta-cardiac myosin heavy chain gene (MYH7) can lead to hypertrophic

122 oded within an intron of beta-cardiac muscle myosin heavy chain gene (Myh7).

123 sed by a premature stop codon in the cardiac myosin heavy chain gene myh6.

124 Alternative splicing of myosin heavy chain gene transcripts in Drosophila melano

125 We show that myo-sex, a myosin heavy-chain gene also in the M-locus, was require

126 study, we show that six fast muscle-specific myosin heavy chain genes have unique expression patterns

127 An expression profile of human skeletal myosin heavy chain genes suggests that human myosin heav

128 bridge kinetics bat and songbird SFM express myosin heavy chain genes that are evolutionarily and ont

129 myo2-E1) and deletion mutations of the other myosin heavy-chain genes.

130 cepted hypothesis for this phenotype is that myosin heavy chain HCM mutations increase muscle contrac

131 ectrometry analysis revealed that non-muscle myosin heavy chain II A (NMHC IIA) is a protein targeted

132 antibody (m21G6) directed against nonmuscle myosin heavy chain II may inhibit IgM binding and reduce

133 A highly conserved self-antigen, nonmuscle myosin heavy chain II, has been identified as a target o

134 hypomorphic mice, showed that Myh10 encoding myosin heavy chain II-B is critical for cardiac and brai

135 cific alternative splicing of the non-muscle myosin heavy chain II-B pre-mRNA as a model.

136 Subset 6 CLL mAbs recognize nonmuscle myosin heavy chain IIA (MYHIIA).

137 with rat liver mitochondrial DNA: non-muscle myosin heavy chain IIA and beta-actin.

138 of the MYH9 gene that encodes the nonmuscle myosin heavy chain IIA are associated with diabetic neph

139 we conclude that the minimal binding site on myosin heavy chain IIA corresponds to A1907-G1938; there

140 ated with a missense mutation (E706K) in the myosin heavy chain IIa gene.

141 A4 and the C-terminal fragments of nonmuscle myosin heavy chain IIA has been studied by equilibrium a

142 sitive lipase, glutathione peroxidase-1, and myosin heavy chain IIa in quadriceps of control mice but

143 lysis suggest some beta-actin and non-muscle myosin heavy chain IIA reside within human mitochondria

144 gene silencing of MYH9 (encoding non-muscle myosin heavy chain IIA), or the closely related MYH10 ge

145 so identified a new Rab3 effector, nonmuscle myosin heavy chain IIA, as part of the complex formed by

146 enriched at many muscle gene promoters (MCK, Myosin heavy chain IIa, Six4, Calcium channel receptor a

147 d that RUNX1-mediated silencing of nonmuscle myosin heavy chain IIB (MYH10) was required for megakary

148 Proteomic screening identified nonmuscle myosin heavy chain IIB (NMHCIIB), a subunit of nonmuscle

149 sely related MYH10 gene (encoding non-muscle myosin heavy chain IIB), altered the topology and increa

150 tion of the actin-bundling protein nonmuscle myosin heavy chain IIB, and junction remodeling.

151 in, fibrillarin, nuclear lamin B1, nonmuscle myosin heavy chain IIB, paxillin, Sec61 beta, tight junc

152 and PCNA and decreased protein expression of myosin heavy chain in medial and neointimal VSMC.

153 s-sectional area and levels of the embryonic myosin heavy chain in regenerating muscle.

154 onal area and levels of embryonic isoform of myosin heavy chain in regenerating tibial anterior muscl

155 ated fibers, and the expression of embryonic myosin heavy chain in skeletal muscle of mdx mice.

156 The decrease in myosin heavy chain in the control sample was found after

157 I have identified mRNAs associated with five myosin heavy chains in the fission yeast Schizosaccharom

158 beta1 integrin, Pax7, myogenin and embryonic myosin heavy chain, indicating a restoration of the musc

159 arteries coexpressed smooth muscle actin and myosin heavy chain, indicating a smooth muscle cell iden

160 One of these RNAs, myosin heavy chain, is critical in presynaptic sensory n

161 Myosin heavy chain isoform composition of muscle samples

162 Myofiber size, myosin heavy chain isoform expression, and satellite cel

163 Cardiac myosin heavy chain isoform gene expression also showed a

164 erved decreased mRNA transcription levels of myosin heavy chain isoform IIa and a lower densitometric

165 er and relay domains vary between Drosophila myosin heavy chain isoforms due to alternative mRNA spli

166 We conclude that myosin heavy chain isoforms influence both SA kinetics a

167 reparation, the jump muscle, to determine if myosin heavy chain isoforms influence the magnitude and

168 ation, as shown by the expression profile of myosin heavy chain isoforms, as well as the upregulation

169 layed in these mutant animals: expression of myosin heavy chain isoforms, the elimination of polyneur

170 ping, differentially regulated expression of myosin heavy chain isoforms.

171 1)R]), p47(phox) NADPH oxidase subunit, beta-myosin heavy chain isozyme switch, accumulation of AGE,

172 Myosin II assembly is regulated by myosin heavy chain kinase-mediated phosphorylation of it

173 Within this group, only eEF2K and myosin heavy chain kinases (MHCKs) have known substrates

174 Ectopically expressed myosin heavy chain kinases affinity purified from corA(-

175 normal in comparison with the alpha and beta myosin heavy chain knockdowns and controls.

176 ardiac myocytes and their inhibition blocked myosin heavy chain loss and myocyte atrophy, whereas inh

177 3, resulting in atrogin1/MAFbx upregulation, myosin heavy chain loss, and myotube atrophy.

178 We show alpha-myosin heavy chain MerCreMer and the MLC-2v promoters ar

179 ieved in adult mice using an alphaMHC (alpha-myosin heavy chain)-MerCreMer system.

180 ated a new transgenic mouse, alphaMHC (alpha myosin heavy chain)-MerDreMer-Ki67p-RoxedCre (denoted al

181 IP), increased SRF activity, as well as beta-myosin heavy chain (MHC) and myocardin expressions.

182 a majority of sarcomeric proteins, including Myosin Heavy Chain (MHC) and Tropomyosin, require Hoip f

183 Troponin I (TnI) and myosin heavy chain (MHC) are two contractile regulatory

184 hy mutations in the filament-forming tail of myosin heavy chain (MHC) cause hypertrophic or dilated c

185 mutation at residue 403 (R403Q) in the beta-myosin heavy chain (MHC) caused a severe form of FHC was

186 HCM-causing Arg403Gln mutation in the alpha-myosin heavy chain (MHC) gene is inhibited by doxycyclin

187 rce production was reduced in OA patients in myosin heavy chain (MHC) I and IIA fibres (both P < 0.05

188 ts showed decreased cross-bridge kinetics in myosin heavy chain (MHC) I and IIA fibres, partially due

189 t was 64, 54, 160, and 138% more abundant in myosin heavy chain (MHC) I/IIa, MHC IIa, MHC IIa/IIx, an

190 myosin IIB and increased phosphorylation of myosin heavy chain (MHC) IIA on target sites known to re

191 n the cross sectional area and proportion of myosin heavy chain (MHC) IIB and low succinate dehydroge

192 on of Pax-7, MyoD, Myf5, Myf6, myogenin, and myosin heavy chain (MHC) in obestatin-infused rats when

193 hortening velocities, and/or a difference in myosin heavy chain (MHC) isoform content in chimpanzee r

194 erse ventricular remodeling characterized by myosin heavy chain (MHC) isoform switch and fibrosis, de

195 One outstanding question is whether the myosin heavy chain (MHC) isoforms alone account for thes

196 Myosin heavy chain (MHC) isoforms in goat muscles and th

197 d of sarcomeres and capable of deacetylating myosin heavy chain (MHC) isoforms.

198 sarcomeres and was capable of deacetylating myosin heavy chain (MHC) isoforms.

199 To investigate myosin heavy chain (MHC) phosphorylation roles in 3D mig

200 We performed a proteomic analysis of myosin heavy chain (MHC) phosphorylation sites in MDA-MB

201 In gel samples made without salt (Lot A), no myosin heavy chain (MHC) polymerization was observed, on

202 myogenesis that inhibit transcription of the myosin heavy chain (MHC) protein family.

203 ing our system for recombinant expression of myosin heavy chain (MHC) proteins in whole transgenic fl

204 and dimensions and caused a shift from alpha-myosin heavy chain (MHC) to beta-MHC gene expression.

205 Myosin heavy chain (MHC) was not carbonylated in chilled

206 Gel electrophoresis showed loss in myosin heavy chain (MHC), and a resulting increase in cr

207 on was associated with an increased ratio of myosin heavy chain (MHC)-beta to MHC-alpha and upregulat

208 pression of pyruvate dehydrogenase kinase 4 (myosin heavy chain (MHC)-PDK4 mice), an inhibitor of pyr

209 mutations in sarcomere proteins such as the myosin heavy chains (MHC) are the leading genetic causes

210 Fiber type (myosin heavy chain [MHC] isoform) and glucose uptake wer

211 isome proliferator-activated receptor-alpha (myosin heavy chain [MHC]-PPARalpha mice) exhibit phenoty

212 mice with higher expression levels of TRAF2 (myosin heavy chain [MHC]-TRAF2(HC)).

213 creased endogenous MyoD, Myogenin, and Myh3 (myosin heavy chain, [MHC] gene) mRNAs but not the cognat

214 u), prevents the interaction of RLC with the myosin heavy chain (MHCII) to form functional NMII units

215 lasia and ventricular septal defects in beta-myosin heavy chain-miR-195 transgenic mice.

216 nd up-regulated SM22, SM alpha-actin, and SM myosin heavy chain mRNA and protein levels.

217 own to be affected (in 2005) by a novel beta-myosin heavy-chain mutation that caused HCM, after an of

218 Nandrosol in Longissimus dorsi muscle, where myosin heavy chain (MYH) was significantly up-regulated.

219 cted protein-altering mutations in embryonic myosin heavy chain (MYH3) in three families.

220 , DCM) associated with mutations in the beta-myosin heavy chain (MYH7) gene product (Myosin-7).

221 , we have cloned the rat isoform of class II myosin heavy chain MyH7B in brain.

222 MIIA, NMIIB, and NMIIC, containing different myosin heavy chains (MYH9, MYH10, and MYH14, respectivel

223 by embryonic day 12.5 (E12.5), as assayed by myosin heavy chain (MyHC) and Myogenin staining.

224 d the candidate gene approach, targeting the myosin heavy chain (MyHC) gene.

225 fibers express five highly conserved type-II myosin heavy chain (MyHC) genes in distinct spatial and

226 The purpose of this study was to assess myosin heavy chain (MyHC) isoform expression and satelli

227 al area, myofiber size, satellite cells, and myosin heavy chain (MyHC) isoform expression was examine

228 histochemical analyses were used to quantify myosin heavy chain (MyHC) isoform expression, cross-sect

229 s that failed to express some characteristic myosin heavy chain (MyHC) proteins.

230 on index and myotube diameter; likewise, the myosin heavy chain (MyHC)-IIB isoform (encoded by Myh4)

231 myofibril, before any measurable decrease in myosin heavy chain (MyHC).

232 The myosin heavy-chain (MyHC) gene family comprises multiple

233 The thick-filament component myosin heavy chain MYO-3 and the M-line component UNC-89

234 We also performed a detailed analysis of myosin heavy chain, myosin light chain, and myosin light

235 R2 and SERCA2, and the myofilament proteins, myosin heavy chain, myosin light chains and subunits of

236 ch donor indicated the actin-tropomyosin and myosin heavy chain-myosin light chain 1 interactions ind

237 of a disulfide-linked actin-tropomyosin and myosin heavy chain-myosin light chain 1.

238 (rs9583277) within the gene encoding for the myosin heavy-chain Myr 8 (MYO16), which has been implica

239 y studying mice and cells in which nonmuscle myosin heavy chain (NMHC) II-A is genetically replaced b

240 2 transgenic mouse models in which nonmuscle myosin heavy chain (NMHC) II-A was genetically replaced

241 splicing of a cassette exon N30 of nonmuscle myosin heavy chain (NMHC) II-B in the mouse central nerv

242 1 CM-specific knockout (KO) mice using alpha-Myosin Heavy Chain-nuclear Cre (ZO-1cKO) and investigate

243 tissues stimulates phosphorylation of the NM myosin heavy chain on Ser1943 and causes NM myosin filam

244 ACh stimulated the phosphorylation of NM myosin heavy chain on Ser1943 in tracheal SM tissues, wh

245 pha-skeletal muscle actin (p<0.05), and beta-myosin heavy chain (p<0.05) were observed in AC6-KO mice

246 ed in BALB/c mice by immunization with alpha-myosin heavy chain peptide and complete Freund's adjuvan

247 the mechanoenzyme myosin II, independent of myosin heavy-chain phosphorylation, thus increasing cell

248 To address the effect of absence of NaCl on myosin heavy chain polymerization during two-step surimi

249 RT-PCR analysis using rat- or human-specific myosin heavy chain primers revealed that the myosin heav

250 pression of PPARgamma is driven by the alpha-myosin heavy chain promoter (alphaMHC-PPARgamma) were pr

251 In contrast, myosin heavy chain promoter (MHC)-ATGL mice were resista

252 tracycline-regulated, cardiac-specific alpha-myosin heavy chain promoter (V1A-TG).

253 promoter or the cardiomyocyte-specific alpha myosin heavy chain promoter, we identify a rare populati

254 ominant negative CELF protein under an alpha-myosin heavy chain promoter.

255 ardiomyocytes under the control of the alpha-myosin heavy chain promoter.

256 ardiomyocytes under the control of the alpha-myosin heavy chain promoter.

257 h driven by the cardiomyocyte-specific alpha-myosin heavy chain promoter.

258 inase under the control of the smooth muscle myosin heavy-chain promoter resulted in cardiopulmonary

259 conditional ROCK2(flox/flox) mice and alpha-myosin heavy-chain promoter-driven Cre recombinase trans

260 r gamma 1 (PPARgamma1) via the cardiac alpha-myosin heavy-chain promoter.

261 crossed into merCremer mice under the alpha-myosin heavy-chain promoter.

262 expression of JunD via the alpha MHC (alpha- myosin heavy chain) promoter (alpha MHC JunD(tg)) were p

263 a lower densitometric ratio of fast-to-slow myosin heavy chain protein content.

264 Overexpression of the beta-myosin heavy chain protein contributes to the pathologic

265 OligoCS maintains almost all myosin heavy chain protein degradation as observed in th

266 rophy attributable to a specific decrease in myosin heavy chain protein.

267 f2ca translation and level of Mef2c and slow myosin heavy chain proteins caused by inactivity.

268 METHODS AND We treated 2-year-old beta-myosin heavy-chain Q403 transgenic rabbits with establis

269 modeling, including decreased alpha- to beta-myosin heavy chain ratios, and induced maladaptive chang

270 These mice were crossed with alpha-myosin heavy chain reverse transcriptional transactivato

271 [GSK3beta], a 20-fold up-regulation of beta myosin heavy chain RNA and elevated G(s)alpha/G(i)alpha

272 ons in the beta-cardiac/slow skeletal muscle myosin heavy chain rod.

273 ated NM myosin RLC phosphorylation and by NM myosin heavy chain Ser1943 phosphorylation.

274 ection is MYH11, which encodes smooth muscle myosin heavy chain (SM-MHC).

275 cells in the PKJ co-expressed smooth muscle myosin heavy chain (smMHC) and several other smooth musc

276 ne renal pelvis do not express smooth muscle myosin heavy chain (smMHC) but are in close apposition t

277 muscle (ASM) against a loss of smooth muscle myosin heavy chain (SMMHC) expression.

278 he interaction between CBFbeta-smooth muscle myosin heavy chain (SMMHC; encoded by CBFB-MYH11) and RU

279 eversed end-diastolic flow contained reduced myosin heavy chain, smooth muscle actin, and desmin, and

280 Birth weight correlated positively with CSE, myosin heavy chain, smooth muscle actin, and desmin, and

281 CSE correlated positively with myosin heavy chain, smooth muscle actin, and desmin.

282 ecific (Tie2, Cdh5, Pdgfb) and smooth muscle myosin heavy chain-specific Cre driver mouse lines to pr

283 tin interacts with the neuronal (non-muscle) myosin heavy chain subunits, motors of nucleokinesis dur

284 th decreased alpha myosin and increased beta myosin heavy chains, suggesting an alpha-to-beta convers

285 eration marked by dysregulation of embryonic myosin heavy chain temporal expression.

286 ivided into four categories according to the myosin heavy chain that they express: I, IIA, IIX and II

287 to the light meromyosin (LMM) region of the myosin heavy chain, the underlying molecular mechanism c

288 r than heat-induced breakdown of part of the myosin heavy chains, the 2-DE pattern of cooked ham was

289 ming the disorder from a disease of the beta-myosin heavy chain to a disease of the cardiac sarcomere

290 olic heart failure via targeting the cardiac myosin heavy chain to increase myocardial contractility.

291 levels of differentiation markers (myogenin, myosin heavy chain, troponinT-1, and Pax3) and impaired

292 C)-specific isoforms of alpha-actin and beta-myosin heavy chain, two major components of the SMC cont

293 Binding to the myosin heavy chain was associated with a large conformat

294 This selective degradation of myosin heavy chain was not accompanied by a decrease in

295 on rate, surface area, or expression of beta-myosin heavy chains was significantly greater in AKAP5(-

296 h shares sequence identity with beta-cardiac myosin-heavy chain, was used because of its stability in

297 des could lower the denaturation of crayfish myosin heavy chain when compared to the control.

298 including SM alpha-actin, SM22alpha, and SM myosin heavy chain, whereas Olfm2 overexpression promote

299 ) stimulated the binding of S100A4 to the NM myosin heavy chain, which was catalysed by RhoA GTPase v

300 latory light chain (RLC) binding site in the myosin heavy chain with concomitant dissociation of the