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1 were ameliorated by the presence of dietary n-3 fatty acid.
2 concentrations of long-chain polyunsaturated n-3 fatty acids.
3 studies of AMD risk reduction by long-chain n-3 fatty acids.
4 script levels in the mice fed a diet of high n-3 fatty acids.
5 igh dietary AA but mitigated by high dietary n-3 fatty acids.
6 e not correlated with dietary consumption of n-3 fatty acids.
7 infarction, and stroke in subjects consuming n-3 fatty acids.
8 10% Scia in diets balanced out with n-6 and n-3 fatty acids.
9 rapid increase in erythrocyte DHA and total n-3 fatty acids.
10 ifferences based on metabolism of long-chain n-3 fatty acids.
11 uming higher quantities of n-6 or long-chain n-3 fatty acids.
12 se genes are responsible for many effects of n-3 fatty acids.
13 anic is not a guarantee of higher long chain n-3 fatty acids.
14 the origin of specific volatiles from parent n-3 fatty acids.
15 ing optimal amounts of dietary n-9, n-6, and n-3 fatty acids.
16 may be mediated by an enzymatic affinity for n-3 fatty acids.
17 n of saltwater fish and intake of long-chain n-3 fatty acids.
18 received placebo (adjusted hazard ratio with n-3 fatty acids, 0.97; 95% confidence interval, 0.88 to
21 after we adjusted further for marine-derived n-3 fatty acids (22 mum, 95% CI: -1 to 46 mum, p = 0.065
22 eas consumption of the vegetable oil-derived n-3 fatty acid a-linolenic acid is not as effective.
23 were similar for estimated intake of marine n-3 fatty acids: a 1 g/day higher intake was associated
24 domains) in relation to baseline intakes of n-3 fatty acids (absolute and relative to n-6 fatty acid
27 in Barnes maze performance compared with the n-3 fatty acid-adequate rats during the initial training
31 re studied in chicken patties, enriched with n-3 fatty acids, after 8days of storage at 4 degrees C,
32 s have evaluated the association between the n-3 fatty acid alpha-linolenic acid (ALA) and the incide
39 %), of whom 733 of 6239 (11.7%) had received n-3 fatty acids and 745 of 6266 (11.9%) had received pla
42 ociation between the ratio of dietary n-6 to n-3 fatty acids and bone mineral density (BMD) in 1532 c
43 d the relation between the dietary intake of n-3 fatty acids and chronic obstructive pulmonary diseas
46 We further analyzed the effects of n-6 and n-3 fatty acids and found that the PUFA-APOA5 interactio
47 ineered fat-1 mice, which can convert n-6 to n-3 fatty acids and have a balanced ratio of n-6 to n-3
48 showed no evidence that supplementation with n-3 fatty acids and instructions to reduce arachidonic a
49 evidenced by an increase in the ratio of n-6/n-3 fatty acids and levels of 4-hydroxynonenal, a marker
51 sible to make firm recommendations regarding n-3 fatty acids and the prevention of dementia and AMD.
52 ions between fish, shellfish, and long-chain n-3 fatty acids and the risk of T2D in a middle-aged Chi
54 ever, the relation between dietary intake of n-3 fatty acids and ventricular arrhythmias has not been
55 and spring proved to have a high content of n-3 fatty acids and vitamin D, and hence they serve as a
56 tive was to determine whether walnuts (plant n-3 fatty acid) and fatty fish (marine n-3 fatty acid) h
57 34)), levels of polyunsaturated fatty acids, n-3 fatty acids, and docosahexaoenic acid relative to to
59 nolenic acid (ALA), a plant-derived omega-3 (n-3) fatty acid, and age-related macular degeneration (A
60 nolenic acid (ALA), a plant-derived omega-3 (n-3) fatty acid, and cardiovascular disease (CVD) risk h
61 uding saturated fatty acids (SFAs), omega-3 (n-3) fatty acids, and refined sugar, with hippocampal-de
62 rticularly lutein and zeaxanthin, as well as n-3 fatty acids, appears beneficial for AMD and possibly
64 We sought to examine whether marine-derived n-3 fatty acids are associated with less atherosclerosis
66 n-6 fatty acids and concomitant decrease in n-3 fatty acids are thought to be a major driver of the
68 ioperative immunonutrition (IMN) enriched in n-3 fatty acids, arginine, and nucleotides may improve p
69 ificantly decreased among patients receiving n-3 fatty acids, as compared with those receiving placeb
70 ple, dietary intake of fish and fish-derived n-3 fatty acids, as well as plasma biomarkers of fish in
72 3) (at a dose of 2000 IU per day) and marine n-3 fatty acids (at a dose of 1 g per day) in the primar
74 indicate that syndecan 1 is up-regulated by n-3 fatty acids by a transcriptional pathway involving P
77 iet that is high in omega-3 polyunsaturated (n-3) fatty acids can slow disease progression in patient
78 ga-3 fatty acids (omega-3-FAs; also known as n-3 fatty acids) can exert potent anti-inflammatory effe
79 th health-related biomarkers [e.g., omega-3 (n-3) fatty acids, citrate, alpha1-acid glycoprotein, HDL
80 In contrast to their agonistic properties, n-3 fatty acids competitively inhibit the responses of v
81 ffects of varying n-9, n-6, and longer-chain n-3 fatty acid composition on markers of coronary heart
82 ctive was to examine the association between n-3 fatty acid consumption and ventricular ectopy among
83 tigate whether a diet enriched with fish and n-3 fatty acid consumption are associated with changes i
85 udies have evaluated the effects of fish and n-3 fatty acid consumption on fatal coronary heart disea
86 se findings extend existing evidence linking n-3 fatty acid consumption to a reduced risk of ventricu
87 ariable adjustment, neither fish nor dietary n-3 fatty acid consumption was significantly associated
88 im was to study the associations of fish and n-3 fatty acid consumption with risk of total major chro
89 problems in evaluating the health effects of n-3 fatty acid consumption, highlighted challenges to re
94 tudy, the authors demonstrate that rats with n-3 fatty acid deficiency display spatial learning defic
97 upplementation, combined with the effects of n-3 fatty acid deficiency, on acute blue-light photochem
99 s of brain docosahexaenoic acid (DHA) in the n-3 fatty acid-deficient rats in comparison to n-3 fatty
104 onics have higher levels of glycolipids with n-3 fatty acids (DGDG 36:3; SQDG 36:3; MGDG 36:6) compar
105 antiinflammatory, and vasodilatory omega-3 (n-3) fatty acids (DHA and EPA) are significantly reduced
107 ovascular risk factors, daily treatment with n-3 fatty acids did not reduce cardiovascular mortality
110 2(-/-)/Cx3cr1(-/-) mice that ingested a high n-3 fatty acid diet showed a slower progression of retin
112 enter addresses is whether botanical n-6 and n-3 fatty acids directly block recognized biochemical pa
114 esult in altered brain concentrations of the n-3 fatty acid docosahexaenoic acid (DHA) during the per
115 of the transcription factor PPARgamma by the n-3 fatty acid docosahexaenoic acid (DHA) is implicated
118 ns unresolved, possibly due to low levels of n-3 fatty acids docosahexaenoic acid (DHA) and eicosapen
122 r diets with different levels of the various n-3 fatty acids during pregnancy and lactation, and thei
123 d interventional, assessing the influence of n-3 fatty acids during pregnancy or the early postpartum
124 itro experiments showed that addition of the n-3 fatty acid eicosapentaenoic acid or PGE(3) inhibited
125 at consuming fish or fish oil containing the n-3 fatty acids eicosapentaenoic acid (EPA) and docosahe
126 rvings/wk), especially species higher in the n-3 fatty acids eicosapentaenoic acid (EPA) and docosahe
127 attributed to the marine-derived long-chain n-3 fatty acids eicosapentaenoic acid (EPA) and docosahe
128 correlated with the RBC long-chain omega-3 (n-3) fatty acids eicosapentaenoic acid (EPA) and docosah
130 flaxseed addition in the chicken feed (i.e., n-3 fatty acid enrichment), and for the different packag
132 ns, a significant increase in serum omega-3 (n-3) fatty acids (EPA and DHA), and a decrease in serum
134 iew current evidence on the relation between n-3 fatty acids, especially docosahexaenoic acid (DHA),
136 We questioned if acute administration of n-3 fatty acids (FA) carried in n-3 rich triglyceride (T
138 h low dietary omega-6 (n-6) or high omega-3 (n-3) fatty acid (FA) content resulted in reduced body fa
141 and Treatment of Coronary Heart Disease with n-3 Fatty Acids," faculty who presented at the conferenc
142 Studies on the relation between dietary n-3 fatty acids (FAs) and cardiovascular disease vary in
146 the relation of plasma and dietary omega-3 (n-3) fatty acids (FAs) with heart failure (HF) risk have
147 Nevertheless, the most consistent effect of n-3 fatty acids feeding in rats is to decrease lipogenes
148 then recommendations for specific intakes of n-3 fatty acids for different conditions relating to car
149 Alpha-linolenic acid, an intermediate-chain n-3 fatty acid found primarily in plants, may decrease t
153 fat-1 transgenic pigs produce high levels of n-3 fatty acids from n-6 analogs, and their tissues have
162 Most of the health benefits observed for n-3 fatty acids have been attributed to the marine-deriv
165 plant n-3 fatty acid) and fatty fish (marine n-3 fatty acid) have similar effects on serum lipid mark
166 t Greenland Eskimos, who have a diet high in n-3 fatty acids, have a lower mortality from coronary he
167 W n-6) or a diet with a relative increase in n-3 fatty acid (HIGH n-3) compared with the CTR from pos
168 al cord blood samples (n = 101), we measured n-3 fatty acids, IgE concentrations, and immunologic res
169 ammation in animal models, we tested whether n-3 fatty acids impact SPM profiles in patients with CAD
170 ctable way to increase a specific long-chain n-3 fatty acid in plasma, tissues, or human milk is to s
171 Docosahexaenoic acid (DHA) is the principal n-3 fatty acid in tissues and is particularly abundant i
173 imed to investigate the effect of long-chain n-3 fatty acids in blood on the risk of nonfatal MI.
176 d, and because of limited interconversion of n-3 fatty acids in humans, ALA supplementation does not
178 rized databases were searched for studies of n-3 fatty acids in immune-mediated diseases from 1966 to
185 vitro studies indicates a beneficial role of n-3 fatty acids in the prevention and management of card
186 ty acids and have a balanced ratio of n-6 to n-3 fatty acids in their tissues and organs independent
187 Triglyceride synthesis could be reduced by n-3 fatty acids in three general ways: reduced substrate
188 d activation and provides specificity toward n-3 fatty acids in which the corresponding n-3 acyl-CoAs
189 acid (DHA, 22:6n-3), the principal omega-3 (n-3) fatty acid in brain gray matter, positively regulat
190 moderators of clinical response to omega-3 (n-3) fatty acids in subjects with major depressive disor
192 Dietary recommendations have been made for n-3 fatty acids, including alpha-linolenic acid (ALA), e
194 wide diversity of dietary intakes of n-6 and n-3 fatty acids influences tissue compositions of n-3 lo
197 fatty acid intake (in whites) and long-chain n-3 fatty acid intake (in African Americans) such that p
199 imilar association was found between seafood n-3 fatty acid intake and prostate cancer mortality (RR(
200 Our results support a protective effects of n-3 fatty acid intake and the n-7 saturation index again
201 d 0.025) remained negatively associated with n-3 fatty acid intake in women and men, and large HDLs (
205 e was to determine whether habitual omega-3 (n-3) fatty acid intake is associated with the rate of in
207 t is reasonable to hypothesize that maternal n-3 fatty acid intakes might have significant effects on
209 We examined the relation of fish and seafood n-3 fatty acid intakes with prostate cancer incidence an
210 PUFA intake, specifically n-6 and long-chain n-3 fatty acid intakes, and multiple lipid measures in t
211 ch as carbohydrates and protein, leucine and n-3 fatty acid intakes, such as of EPA, may be important
213 e trafficking of stable isotopically labeled n-3 fatty acids into phosphatidylcholine and phosphatidy
216 blue light-induced damage, whereas adequate n-3 fatty acid levels reduced the damage in the parafove
218 entre randomised trial of low-dose fish oil (n-3 fatty acids <1080 mg/day) in drug resistant epilepsy
219 hythmias by showing that a greater intake of n-3 fatty acids may be associated with low ventricular e
220 ndicate that the cardioprotective effects of n-3 fatty acids may be attributed to a number of distinc
221 d and SCD supports the hypothesis that these n-3 fatty acids may have antiarrhythmic properties.
225 nthophylls lutein (L) and zeaxanthin (Z) and n-3 fatty acids may reduce this damage and lower the ris
227 T1A, was strongly associated with markers of n-3 fatty acid metabolism, including degree of unsaturat
229 ignificant increase of phospholipids bearing n-3 fatty acids (most in PC and PE) was also recorded.
230 her concentrations of both n-6 (omega-6) and n-3 fatty acids of higher elongation and desaturation le
233 Our results support a protective effect of n-3 fatty acids on breast cancer risk and provide additi
234 ent to draw conclusions about the effects of n-3 fatty acids on clinical, endoscopic, or histologic s
235 ntrolled trials that assessed the effects of n-3 fatty acids on clinical, sigmoidoscopic, or histolog
236 spective, double-blind trials, the effect of n-3 fatty acids on depression during pregnancy or the ea
237 low-dose supplementation with B vitamins or n-3 fatty acids on depressive symptoms in cardiovascular
239 east 900 mg (90% or more) of ethyl esters of n-3 fatty acids or placebo daily and to receive either i
240 per liter]) or standard care and to receive n-3 fatty acids or placebo with the use of a 2-by-2 fact
241 -long-chain polyunsaturated fatty acids, the n-3 fatty acids (or omega-3), have distinct and importan
243 risk factors and RBC saturated and omega-3 (n-3) fatty acids, ORs for CAD associated with each SD in
247 and gelled double emulsion, for delivery of n-3 fatty acids (perilla oil at 300g/kg) and hydroxytyro
248 ether the ratio of omega-6 (n-6) to omega-3 (n-3) fatty acids plays a role in tumorigenesis remains t
249 forcement of the antioxidant system, through n-3 fatty acids plus antioxidant vitamin supplementation
250 children had high ratios, a higher intake of n-3 fatty acids predicted a better performance on the pl
251 rse association between intake of long chain n-3 fatty acids [primarily eicosapentaenoic acid (EPA) a
254 Fish were fed diets containing different n-6/n-3 fatty acid ratios (V0.5 or V1) and sesamin contents
257 istent across 3 studies was the finding that n-3 fatty acids reduce corticosteroid requirements, alth
259 idered tentative, and the mechanism by which n-3 fatty acids reduce triglyceride levels in humans rem
262 olic and cardiovascular benefits of omega-3 (n-3) fatty acids, several studies have suggested an adde
264 es support a direct association between poor n-3 fatty acid status and increased risk of maternal dep
267 on trials, that examine the relation between n-3 fatty acids such as DHA and depression and child men
268 both groups, and the addition of aspirin to n-3 fatty acid supplementation did not alter any of the
270 ins were increased to a similar extent after n-3 fatty acid supplementation in both groups, and the a
271 ecursors 18-HEPE, 17-HDHA, and 14-HDHA after n-3 fatty acid supplementation that was significantly at
272 ased to a similar extent in the groups after n-3 fatty acid supplementation, and the D-series resolvi
274 individual effects of vitamin D and omega-3 (n-3) fatty acid supplementation on endometriosis-associa
275 change of serum metabolomics in response to n-3 fatty acid supplements in Chinese patients with type
276 mol per liter) more among patients receiving n-3 fatty acids than among those receiving placebo (P<0.
277 e had 2-fold higher levels of marine-derived n-3 fatty acids than whites and Japanese Americans in th
278 SDA-enriched soybean oil is a land-based n-3 fatty acid that is a sustainable approach to increas
279 te that DHA, but not EPA, is the most potent n-3 fatty acid that suppresses glomerulonephritis and ex
280 ional studies utilizing tissue biomarkers of n-3 fatty acids that more accurately measure dietary con
281 Omega-3 polyunsaturated fatty acids (PUFA, n-3 fatty acids), the key components of fish and flaxsee
283 and other fatty acids, including long-chain n-3 fatty acids, the intake of alpha-linolenic acid was
284 studies fed unphysiologically high doses of n-3 fatty acids, these findings in rats must be consider
285 trate an anticancer (antimelanoma) effect of n-3 fatty acids through, at least in part, activation of
286 ake variations of omega-6 (n-6) and omega-3 (n-3) fatty acids ultimately determine cell membrane inco
287 r prevention, including lycopene, long-chain n-3 fatty acids, vitamin D, vitamin E, and selenium, wer
288 or DRI review, by which sodium, the omega-3 (n-3) fatty acids, vitamin E, and magnesium were identifi
291 percentage of energy from fat, the intake of n-3 fatty acids was significantly associated with fewer
293 ted seafood intake and estimated or measured n-3 fatty acids, whereas associations with self-reported
294 Meat products are generally low in omega-3 (n-3) fatty acids, which are beneficial to human health.
295 icant inverse associations of marine-derived n-3 fatty acids with IMT and CAC prevalence, respectivel
297 is a lack of research on the association of n-3 fatty acids with risk of benign fibrocystic breast c
298 that dietary supplementation with selective n-3 fatty acids would be most beneficial for the treatme
299 ed that children with lower ratios of n-6 to n-3 fatty acids would perform better on tests of plannin
300 phospholipid measures of long-chain omega-3 (n-3) fatty acids would be positively associated with lar