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1 , and as the lowest 30-second value (VE/VCO2(nadir)).
2 than the earlier occuring lowest CRT value (nadir).
3 HIV loads and CD4+ T-cell counts (recent and nadir).
4 re found between left putamen PE/Cr and SaO2 nadir.
5 nly due to a larger decline in the nocturnal nadir.
6 letion among SE reflects the PGC methylation nadir.
7 eperfusion, coinciding with the T cell count nadir.
8 t lost was calculated each year after weight nadir.
9 lasma HIV RNA, reading ability, and CD4 cell nadir.
10 aphic region, year of HIV diagnosis, and CD4 nadir.
11 at its peak compared with when it was at its nadir.
12 pha amplitudes were maximal at low-frequency nadirs.
14 027 persons; median age 43 years, median CD4 nadir 178 cells/mm(3), 72% on CART, and 46% with HAND.
15 efined by any of the following: PSA failure (nadir + 2), hormonal intervention, clinical local or dis
16 ith the use of the prostate-specific antigen nadir + 2-ng/mL definition), freedom from distant metast
17 ycemia was attenuated with SSTR2a treatment (nadir = 3.7 +/- 0.3 vs. 2.7 +/- 0.3 mmol/L in SSTR2a and
18 35.9 degrees C (0.6 degrees C); temperature nadir, 34.3 degrees C (2.8 degrees C); percentage of tim
20 C (2.8 degrees C); percentage of time at the nadir, 4.7% (10.8%); and percentage of time with a tempe
21 3 ml min(-1) 100 g tissue(-1) ) and PO(2) is(nadir) (5.9 +/- 0.9 vs. 4.7 +/- 1.1 mmHg) during twitch
22 jects underwent stepped hypoglycemic clamps (nadir 60 mg/dL) with evaluation of counterregulatory hor
23 ed endothelial colony capacity, a CD34+ cell nadir 7 days after AMI, a negative correlation between C
24 -evoked BAT sympathetic nerve activity (SNA, nadirs: -72 and -95%), BAT temperature (Tbat, -0.5 and -
26 an reduction of 54.2% from baseline), with a nadir about 6 days after injection and an inverse correl
27 essure from baseline to either 60 minutes or nadir after administration of 23.4% saline was 55.6% (se
31 uccess, even when adjusted for CD4(+) T-cell nadir, age at treatment initiation, and other clinical i
33 l therapy, HIV replication, a low CD4 T-cell nadir and a high current CD8 T-cell count are associated
35 demographic characteristics, plasma HIV RNA, nadir and current CD4 cell count in blood, current CD8 c
36 n age of 44 years (SD, 10 years), and median nadir and current CD4(+) T-cell counts of 175 cells/micr
37 higher CSF HIV-1 RNA levels included higher nadir and current CD4(+) T-cell counts, a plasma HIV-1 R
38 for age, sex, race/ethnicity, baseline BMI, nadir and current CD4+ T-cell count, smoking, diabetes a
39 ent level (CAL) (rho = 0.638, P <0.05), CD4+ nadir and diagnosis (rho = 0.586, P <0.05), and CD4+ nad
41 e mean absorbed dose as higher depletions at nadir and longer delays to recovery were noticed for 3.4
43 diagnosis (rho = 0.418, P <0.005), and CD4+ nadir and moderate probing depth (PD) (rho = 0.424, P <0
44 d missing teeth (rho = 0.380, P <0.05), CD4+ nadir and periodontal diagnosis (rho = 0.418, P <0.005),
45 e tissue volume was associated with low CD4+ nadir and prior use of stavudine, didanosine, and indina
46 ased cortisol secretion during the circadian nadir and reduced connectivity were both associated with
47 ed interruptions of ART can lead to CD4 cell nadirs and HIV viremia, and increase the risk of lymphom
48 ignificantly increased weight and hemoglobin nadirs and provided enhanced reticulocytosis and faster
49 and measured lowest PSA concentrations (PSA nadir) and those immediately after treatment (PSA end).
51 1 RNA levels >50 copies/mL, a low CD4 T-cell nadir, and a high CD8 T-cell count were independently as
53 cortisol levels are consistently low at the nadir, and correspondingly the negative feedback was fou
56 occurrences of a morning peak, early morning nadir, and peak on Mondays in ICD therapies using genera
57 ature, percentage of time at the temperature nadir, and percentage of time with a temperature of less
58 e mutant (mdx-dm) mice to mimic pre-pubertal nadir androgen condition resulted in premature death, ma
59 high cortisol secretion during the circadian nadir are both useful for explaining a significant amoun
60 2), fell further after treatment initiation (nadir at 1 week), and then recovered by 6 months (P = .0
61 had a similar hazard ratio curve but a lower nadir at 131 and 69 mm Hg but age >/= 70 had a higher na
64 I and all-cause mortality was convex, with a nadir at 28.6, with greater risk observed throughout the
66 ed a U-curve trend in early pregnancy with a nadir at GW10, whereas fT4 levels were less fluctuated i
70 d satellite sensor TROPOMI (3.5 km x 7 km at nadir), averaged to 0.01 degrees x 0.01 degrees using ph
72 ndomized 1:1 either to 4 cycles of leukocyte nadir-based tailored and dose-dense adjuvant epirubicin
74 vs liberal: 10.3 [2.1] mmol/L; p = 0.02) and nadir blood glucose (4.4 [1.5] vs 5.5 [1.6] mmol/L; p <
76 of patients with predialysis BP>/=160 mmHg, nadir BP<100 mmHg was most potently associated with mort
77 t associated with outcome, and when added to nadir BP, symptom and intervention criteria did not acce
78 ssociated improvement in CD4+ T cell counts (nadir CD4 <200 cells/mm3 with >350 cells/mm3 after ART),
79 ex, ethnicity, hypertension, CD4 cell count, nadir CD4 <200u/L, and time since HIV diagnosis, predict
80 incidence was high even among patients with nadir CD4 cell count >200 cells/microL (140 per 100 000
82 on, sex, entry regimen, duration of ART, and nadir CD4 cell count; CD4 and CD8 cell counts were also
83 0; I(2) 0%, p=0.94) and for each increase in nadir CD4 cell counts of 100 cells per muL, there was a
85 nd increased with age, low CD4/CD8 ratio and nadir CD4 cells < 200mm3 but was not associated with cal
87 d increased with age, low CD4/CD8 ratio, and nadir CD4 count <200 cells/muL but was not associated wi
93 s with inflammatory markers including suPAR, nadir CD4 count, and prevalence of age-associated noncom
94 itis B virus coinfection, group of exposure, nadir CD4 count, CD4:CD8 ratio, and last CD4 level, cale
95 P = 0.005), even after adjusting for age and nadir CD4 count.CONCLUSIONHIV-infected cells persist in
96 fective ART use and early initiation at high nadir CD4 counts might reduce anal high-risk HPV infecti
98 es while receiving sustained cART and higher nadir CD4 percentage between last vaccine dose and serol
99 Study with a longer ART exposure or a lower nadir CD4 percentage had lower mean LV fractional shorte
103 le 2-long terminal repeat (2-LTR), and lower nadir CD4(+) (P < 0.01) were independent predictors of h
104 wer serum lipid levels, HIV replication, low nadir CD4(+) cell count, protease inhibitor use, comorbi
106 with stabilized VR had significantly higher nadir CD4(+) count, compared to those with transient PV
107 on, receipt of statin treatment and having a nadir CD4(+) T-cell count of </=100 cell/microL were the
109 troviral therapy-mediated viral suppression, nadir CD4(+) T-cell count, age, sex, and prior cytomegal
110 , sex, past AIDS, HIV transmission category, nadir CD4(+) T-cell count, antiretroviral therapy, HIV R
111 ng for potential confounders, including age, nadir CD4(+) T-cell count, zidovudine use, and comorbid
112 th changes in baseline age and 5% changes in nadir CD4(+) T-cell percentage, HAART was not associated
113 NA levels, while adjusting for peak HIV RNA, nadir CD4(+)count, CD4/CD8 ratio, CMV IgG levels, time f
114 gnificant evidence among women with a higher nadir CD4+ count (>=350 cells/ul vs <200 cells/ul [adjus
116 .09 [CI, 1.02 to 1.17]; P = 0.007) and lower nadir CD4+ T-cell count (PR, 0.80 [CI, 0.69 to 0.94]; P
117 omen, younger individuals, those with higher nadir CD4+ T-cell count, and those who had received LPV/
118 omen, younger individuals, those with higher nadir CD4+ T-cell counts, and those who had received lop
121 sex, age, treatment history, plasma HIV RNA, nadir CD4+T-cell count, HIV subtype and country were inv
122 sex, age, treatment history, plasma HIV RNA, nadir CD4+T-cell count, HIV subtype, and country were in
123 rolled-mean age, 48.9 +/- 10.2 years; median nadir CD4, 270 cells/mL; tertiary educated, 54%; and HIV
124 s, HCV, HBV co-infection, group of exposure, nadir CD4, and CD4:CD8 ratio and last CD4 levels, calend
125 crosis was associated with white race, lower nadir CD4, prior osteonecrosis, prior fracture, and prio
126 showing a greater than 50% reduction in the nadir chromogranin A level within the 1st year after tre
127 volume abnormalities included CD4 cell count nadir, clinical staging, history of AIDS-defining events
128 showed that MC3-R(-/-) mice exhibit elevated nadir corticosterone as well as a blunted fasting-induce
129 th both doses: -5.8 (95% CI -7.2% to -4.4%) (nadir day 3) compared with -5.5% (95% CI -7.4% to -3.7%)
135 gical outcome at E32, ADC at end of H-I, ADC nadir during H-I and reperfusion-reoxygenation, and area
136 ly rhythm with a zenith at late day time and nadir during the dark in both the Crx(-/-) and the wild
139 AT, the ventilatory response to arousal and nadir end-tidal carbon dioxide were determinants of the
142 cal shape of the J curve was present, with a nadir for cardiovascular events and all-cause mortality
143 The recovery of blood B cells following the nadir from rituximab therapy was characterized by a pred
144 ce intervals, from baseline to 60 minutes or nadir from the six studies from which this information c
145 adjusted model for all-cause mortality: PSA nadir greater than 0.5 ng/mL (adjusted hazard ratio [aHR
146 prostate-specific antigen [PSA] failure, PSA nadir >0.5 ng/mL, PSA doubling time <9 months, and inter
150 The probability of SVR increased with lower nadir Hb for both wild-type and deficient ITPase activit
151 e preoperative hemoglobin (Hb) level and the nadir Hb level during a patient's hospitalization, may b
152 o had a DeltaHb level of less than 50% and a nadir Hb level of 7 g/dL or greater, patients with a Del
154 risk of ischemic complications, even if the nadir Hb level was 7 g/dL or greater (OR, 5.68; 95% CI,
155 with a DeltaHb level of 50% or greater whose nadir Hb level was less than 7 g/dL were at a high risk
156 the DeltaHb concentration following surgery, nadir Hb level, and overall perioperative blood use were
158 Patients were stratified by postoperative nadir hematocrit and the presence of postoperative MI.
159 thout postoperative blood transfusion, lower nadir hematocrit was associated with an increased risk f
160 mice developed a moderate anemia and reached nadir hemoglobin 14 days after injection and partially r
161 sion correlated inversely with admission and nadir hemoglobin, controlling for parasitemia and fever
162 y score-matching according to the hemoglobin nadir, hemoglobin drop, and in the subgroup of uncomplic
163 on on hospital mortality while adjusting for nadir Hgb level, demographic characteristics, admission
164 aseline eGFR, female gender, lower CD4 count nadir, hypertension, diabetes, and cardiovascular diseas
165 diagnostic of early dumping syndrome, and a nadir hypoglycaemia level <50 mg/dl is diagnostic of lat
167 of radiology trainees increased 84.2% from a nadir in 1997 (3080 trainees) to 2011 (5674 trainees) an
168 decrease in PAC use in heart failure, with a nadir in 2009 followed by a subsequent increase (9.1 PAC
170 ing cortisol levels are extremely low at the nadir in contrast to normal subjects, albeit within the
177 al principles: failure to achieve the normal nadir in the cortisol diurnal rhythm, loss of sensitivit
178 had a typical early morning (12 am to 6 am) nadir in therapies, with significantly less than 25% of
179 um ionized calcium and in-hospital AKI, with nadir in-hospital AKI was in serum ionized calcium of 5.
180 how that the large short-lived Hg spike, and nadirs in delta(202)Hg and delta(13)C values at the mari
181 uring hospitalization was observed, with the nadir incidence of in-hospital respiratory failure in SC
182 ssure at the lowest cerebral oximetry index (nadir index) for each 24-hour period of monitoring.
185 tial decrease in Hb level, calculated as the nadir level minus the baseline level (range, -5.8-0 g/dL
188 increase in HBV DNA, compared with previous nadir levels, and hepatitis flare was defined as a great
190 ssociated improvement in CD4+ T-cell counts (nadir, <200/muL; >350/muL after antiretroviral therapy),
191 In a multivariate logistic regression model, nadir lymphocyte count, history of depression, and femal
193 6 vs. 2.1 ug/mL, P = .004) levels, and lower nadir lymphocyte counts (0.09 vs. 0.4 x 10(3) /uL, P = .
194 with acetaminophen-induced hypotension, the nadir mean arterial pressure was 64 mm Hg (95% CI, 54-74
196 thermia were explored, including temperature nadir, mean intraoperative temperature, percentage of ti
198 story of depression, and female sex, but not nadir neutrophil count, were associated with moderate, s
201 6-1.61), but lower among patients with a CD4 nadir of >/=500 cells/mm(3) (IRR 0.73, 95% CI, .53-1.01)
203 younger than age 3 years and declining to a nadir of 0.83 after age 10 years (Spearman's rho = 0.60,
205 drops in deep brain temperature (reaching a nadir of 22.44 +/- 0.74 degrees C), heart rate (from 440
206 en earlier with ctDNA, with a median time to nadir of 37 d (IQR 28-54) compared with a median time to
212 uring hypoglycemia, glucose levels reached a nadir of approximately 2.0 mmol/L, and epinephrine rose
213 tected before peak viral replication and the nadir of CD4(+) T cell depletion predominantly in lamina
214 was obtained prior to depletion, during the nadir of CD8(+) cell depletion, and after CD8(+) lymphoc
228 regimen): -20.4% (95% CI -26.0% to -14.8%) (nadir on day 5) compared with the standard high (14 d) d
229 d to select men for entry at the time of PSA nadir onto randomized trials evaluating the impact on su
230 ned as >0.5-log(10) increase in HCV RNA from nadir or <2-log decrease at day 5, initiated Peg-IFN/RBV
231 HAART], HIV-RNA plasma viral load [PVL], and nadir or current CD4 cell count) with outcomes of anal h
232 h time-updated recent, past, cumulative, and nadir or peak measures of CD4 count and viral load, usin
233 tice criteria to assess whether reported PSA nadir or PSA end concentrations of more than 0.5 ng/mL w
235 as low CD4+ cell counts, whether measured at nadir (OR per 100-cell/muL decrease = 1.53, 95% CI: 1.18
236 ared with 2002 or later), a lower CD4 T-cell nadir (OR, 0.7 [95% CI, .7-.8] per log2 increment), and
237 [Formula: see text]e/[Formula: see text]co2 nadir, or end-exercise [Formula: see text]e/[Formula: se
238 hether insulin action will lock to the peak, nadir, or mean of the normal periodicity of insulin acti
239 pnea-hypopnea index, <30 events per hour) + (nadir oxygen saturation as measured by pulse oximetry >8
241 16.4 events/h (means +/- SD), p = 0.938) or nadir oxyhaemoglobin saturation (79.6 +/- 6.6 vs. 79.7 +
243 increased risk of PCSM in the US trial (PSA nadir p=0.0016; PSA end p=0.017) and Australasian trial
244 had a lower mean intraoperative temperature nadir (P = 0.009) and had a greater number of intraopera
246 ermined whether recent, past, cumulative, or nadir/peak CD4+ T-cell count (CD4) and/or HIV-1 RNA leve
247 d HIV RNA measures, including cumulative and nadir/peak measures during prespecified moving time wind
248 owed a kinetic impactor and provided--from a nadir perspective--the only images of the debris plume.
250 th ITP; prevalence increased with decreasing nadir platelet count (0/4, >=15 x 109/L; 2/9, 10-14 x 10
251 onger disease duration (P = 7 x 10-6), lower nadir platelet count (P = .005), lower platelet count at
252 rospective study of 49 patients with ITP and nadir platelet counts <30 x 109/L and 18 aged-matched he
254 curred at birth, although for some neonates, nadir platelet counts occurred up to 6 days postnatally.
256 , as did peak ferritin (OR, 2.5; P = .0028), nadir platelets (OR, 1.9; P = .00068), hepatomegaly (OR,
258 rwent inpatient noncardiac surgery and had a nadir postoperative hematocrit between 20% and 30%.
263 ergy to pegaspargase would provide a 48-hour nadir serum asparaginase activity (NSAA) >/= 0.10 IU/mL.
264 500-IU/m(2), adjusted every 3 weeks based on nadir serum asparaginase activity (NSAA) determinations.
268 ing liver parenchyma, and they reached their nadir signal intensity by 10 minutes after the administr
270 systolic BP<120 or 120-159 mmHg, an absolute nadir systolic BP<90 mmHg was most potently associated w
274 operative temperature of 35 degrees C as the nadir temperature most predictive of SSI development.
276 we find that large (>7.3 kb) DNA methylation nadirs (termed "grand canyons") can form long loops conn
277 .02) among those who had first-year minimum nadir testosterone </= 0.7, > 0.7 to </= 1.7, and >/= 1.
280 crack guidance is achieved by minimizing the nadir thickness of incorporated v-shaped channels, maxim
281 mix (patient demographics, comorbidity, CD4 nadir, time on therapy, and income from VHA administrati
287 of candidate surrogates (ie, PSA end and PSA nadir values >0.5 ng/mL) alone and when assessed in conj
288 or locally advanced prostate cancer with PSA nadir values exceeding 0.5 ng/mL should be considered fo
289 ficantly less likely to have PSA end and PSA nadir values of more than 0.5 ng/mL than were those trea
290 by a rebound thrombocytosis at day 21, with nadir values significantly lower in septic patients.
291 mean duration of high VL burden from peak to nadir was 76 days (95% confidence interval [CI], 58-93 d
292 re 67.5 (95% CI, 41.2 to 104.3) when the CD4 nadir was less than 200/muL for more than 2 years and 24
296 r ejection fraction 64+/-8%), higher VE/VCO2(nadir) was associated with lower peak exercise cardiac o
297 se (including VE/VCO2(pre-VATslope), VE/VCO2(nadir)) were directly associated with cardiovascular ris
298 This approach had minimal toxicity with nadir white blood cell counts >2.7 K/microL 2 weeks afte
299 T-cell counts in all patients declined to a nadir within < 1 day and recovered to baseline within a