ライフサイエンスコーパス: nanogram

1 10 s (absolute mass detection of less than a nanogram).

2 acceptable daily intake set by the FDA of 96 nanograms.

3 The lipid is generated in nanogram amounts by platelets from endogenous arachidona

4 KT cell activation in liver and spleen using nanogram amounts of antigen.

5 ing techniques, including the utilization of nanogram amounts of DNA, the avoidance of difficulties i

6 tself to high-throughput determination using nanogram amounts of DNA.

7 ification of picomolar amounts of Trolox and nanogram amounts of DOM (corresponding to solutions with

8 capable of eliciting an immune response, and nanogram amounts of HBcAg elicit antibody production in

9 effective characterization using only single nanogram amounts of highly-radioactive, solid compounds.

10 corneal epithelial cells (HCECs) to produce nanogram amounts of IL-8 in the absence of MCP-1 synthes

11 to (12)C expressed as delta(13)C values) for nanogram amounts of individual compounds, such as microb

12 ylation of numerous signaling proteins using nanogram amounts of lysates derived from stimulated livi

13 fically, in solution and in real time, using nanogram amounts of material.

14 emove the nicotine background when detecting nanogram amounts of methamphetamine.

15 throughput was demonstrated by isolation of nanogram amounts of microRNA from acoustically trapped u

16 ation and RNA-Seq with methods optimized for nanogram amounts of moderately degraded RNA enabled us t

17 cribe a quantitative assay for measuring low nanogram amounts of oleamide in biological fluids using

18 Nanogram amounts of protein (143 ng) were effectively pr

19 s of mammalian cell lysates that contain low nanogram amounts of protein.

20 It can also be used when only nanogram amounts of rare samples are available.

21 r and normal genomes can be made by PCR from nanogram amounts of restriction endonuclease cleaved DNA

22 y unknown guest molecule from only micro- or nanogram amounts of the guest molecule.

23 of determining DPD mRNA expression levels in nanogram amounts of total RNA.

24 Using this system, we have identified low nanogram amounts of yeast proteins separated by high-res

25 Thus, hepatocytes respond to nanogram concentrations of LPS through a TLR4 response p

26 say (ELISA) has been developed for measuring nanogram concentrations of semisynthetic pneumocandin an

27 acellular growth of M. tb despite containing nanogram concentrations of TNF-alpha and IFN-gamma.

28 Sustained-release pellets, releasing 500 nanograms/day of BMP-4 for a maximum of 3 months, were i

29 he quartz crystal microbalance (QCM) has sub-nanogram detection capabilities, is label-free, is inexp

30 ults presented in this paper demonstrate low nanogram detection limits ( < 10 ng or < 15 pmol) for no

31 While low-nanogram detection limits are observed in these prelimin

32 Low-nanogram detection limits were achieved for HMTD, TrATrP

33 Low nanogram detection limits were obtained for the compound

34 vivo, RvD1 and AT-RvD1 proved equipotent (at nanogram dosages), limiting polymorphonuclear leukocyte

35 mediate landing on a human host even at sub-nanogram dosages.

36 on were enhanced by the presence of LPS at a nanogram dose in SCD but not control human blood.

37 TA1-DD were highly immunogenic when given in nanogram doses by the s.c., oral, or nasal routes, induc

38 n with nanoliposome particles decorated with nanogram doses of hemagglutinin protected mice from homo

39 We have previously shown that nanogram doses of these 30- to 32-kDa fibronectin-bindin

40 When administered in vivo at nanogram doses, c(HS4-4) enhanced Th17 expansion, and in

41 .033) were detected after Serp-1 infusion at nanogram doses.

42 resolution >80 and a detection limit of low nanograms for the analysis of common explosives (RDX, PE

43 ctosidase activity found 8.3 and 9.8 ng/mug (nanogram fusion protein per microgram sample) for batche

44 the volume (nanogram/milliliter) and lipid (nanogram/gram lipid) basis, were assessed in relation to

45 viral strain and robustly enhance low-dose (nanograms) H3N2 vaccine-induced immune responses and pro

46 fying salicylic acid at the level of several nanograms in situ, the simple paper-based electroanalyti

47 mM, NDMA is still present in the hundreds of nanograms in some metformin products.

48 Doses as low as 10 nanograms injected intracerebroventricularly were effect

49 -long DNA template within seconds from a sub-nanogram input quantity, a step towards low-input DNA se

50 ion, detecting cancer abnormalities with sub-nanogram inputs.

51 s for triplicate injections occurring on the nanogram level for iron ( approximately 24 ng) with vari

52 of proteins, particularly at the picogram-to-nanogram level of proteins.

53 single-cell proteomics from the picogram to nanogram level of proteins.

54 techniques can detect such molecules at the nanogram level or lower.

55 umin standards was found to be on the single-nanogram level with 200-microL injections.

56 Several peptides exhibited activity at the nanogram level.

57 and reproducible proteomic profiling of low nanogram-level complex biological samples.

58 droxymethylation in regions up to 10 kb from nanogram-level input.

59 We have developed a nanogram-level quantitative protein assay based on the b

60 ation of threefold more protein ratios among nanogram-level samples.

61 bled quantification of 12 common polymers at nanogram levels (1-126 ng).

62 cit drugs, and explosives is demonstrated at nanogram levels directly from surfaces in near real time

63 Consequently, we investigated whether nanogram levels of E2 affected PR protein and mRNA level

64 or sCD14 sensitized TLR-expressing cells to nanogram levels of either the synthetic lipopeptide or O

65 ells stimulated the release of microgram and nanogram levels of IL-6, MMP-3, MMP-9, and MCP-1, wherea

66 e optimal conditions, fluorescent bands from nanogram levels of in vitro-produced proteins could be d

67 of laser-isolated tissue samples containing nanogram levels of proteins.

68 Surprisingly, nanogram levels of purified chMMP-13 elicit an angiogeni

69 combinant PTP-1C are required for detection, nanogram levels of recombinant PTP-1B are easily detecte

70 PteGlun the exchange rate is proportional to nanogram levels of SHMT.

71 ics analysis of limited samples, down to sub-nanogram levels of total protein.

72 y via electrophoretic separation of picogram-nanogram levels of total RNA isolated from multiple cell

73 ly focused on analyzing proteins at pico- to nanogram levels, with an emphasis on single-cell proteom

74 o the detection and identification of single-nanogram loadings of 18 explosives and related substance

75 rption and desorption of DNA in the picogram-nanogram mass range.

76 At 1 and 2 months of diabetes, RKBP levels (nanogram/milligram protein) were decreased significantly

77 ed with nonanemic persons, urinary hepcidin (nanograms/milligram of urinary creatinine) was significa

78 factor present in conditioned cell medium at nanogram/milliliter concentrations.

79 congener concentrations, on both the volume (nanogram/milliliter) and lipid (nanogram/gram lipid) bas

80 ster plasma concentrations of four PFASs (in nanograms/milliliter).

81 nough to detect antigen-specific IgGs in the nanogram/mul range and that they provided information fo

82 tal microbalances (QCMs) measure mass on the nanogram (ng) scale.

83 -air analysis of tissue samples (hundreds of nanograms) not subjected to prior preparation, plus the

84 teins at picogram or sub-picogram levels per nanogram of cell lysates.

85 The numbers of HPV-16 and HPV-18 copies per nanogram of cellular DNA at baseline were measured by us

86 (5.8 microg per kilogram of body weight per nanogram of IgE per milliliter or low-dose rhuMAb-E25 (2

87 dose rhuMAb-E25 (2.5 microg per kilogram per nanogram of IgE per milliliter) intravenously on days 0

88 ls indicated that cellular SSAT activity per nanogram of SSAT protein correlated well with the in vit

89 in 18 (50%) of 36 subjects (copy number per nanogram of total DNA, 28 to 2.1 x 10(6)) and in saliva

90 lue of 6.5 x 10 BKV VP1 mRNA copy number per nanogram of total RNA ( <0.00001).

91 tative polymerase chain reaction signals per nanogram of total RNA and using NucleoSpin and mirVana c

92 E) level of Bax mRNA was 336+/-79 copies per nanogram of total RNA, and the level of Bcl-2 mRNA was 3

93 complex of einsteinium, using less than 200 nanograms of (254)Es (with half-life of 275.7(5) days),

94 ding to a limit of detection in the order of nanograms of analyte per gram of tissue.

95 The method was able to quantify nanograms of analytes simultaneously on a single wavelen

96 Ten nanograms of AngII were required to elicit 20% renal vas

97 monstrating a linear working range below 125 nanograms of ctDNA per milliliter solution, and an effec

98 on, and an effective limit of detection of 2 nanograms of ctDNA per milliliter.

99 Thirty nanograms of DNA was sufficient for genome-scale analysi

100 antifiable at concentrations as low as a few nanograms of dsRNA per gram of soil by both Cerenkov cou

101 Two hundred fifty nanograms of E. coli endotoxin was injected into the vit

102 DA-6mA-seq achieves higher sensitivity with nanograms of input DNA and lower sequencing depth than c

103 haplotype germline and cancer genomes using nanograms of input DNA.

104 Micrograms of LF/mg of protein as well as nanograms of iron/micrograms of LF were determined.

105 teomics (Nano3) technique for processing low-nanograms of mammalian cell proteins for proteome profil

106 r of minutes with as little as a few hundred nanograms of material.

107 Lastly, nanograms of NP remained on microplastic surfaces hours

108 UNG) and AP-endonuclease 1 (APE1) within few nanograms of nuclear extract.

109 resis indicated that most organs had several nanograms of PAP1 or PAP2 per milligram of total protein

110 human tissue samples containing as little as nanograms of peptide material in 2 d.

111 With this strategy, nanograms of proteins or peptides inside a band are enou

112 ichia coli (E. coli) proteome consuming only nanograms of proteins.

113 Fifty nanograms of recombinant mouse vascular endothelial grow

114 C) timescale, with consumption of only a few nanograms of sample.

115 We measured the immunoreactive SF content (nanograms of SF per milligram of protein) in tissue extr

116 se extraction (muSPE) device containing only nanograms of silica resin is shown to be effective for t

117 r is a high-sensitivity method that requires nanograms of starting material and has a detection limit

118 of small RNA targets spiked into hundreds of nanograms of the plant total RNA extract with a recovery

119 methodology involves transfer of only a few nanograms of the sample on the TXRF sample support by ge

120 re measured on samples of a few picograms to nanograms of total U.

121 ssion rates ranged from tens to thousands of nanograms of toxicants per milligram of e-liquid vaporiz

122 highly sensitive, requiring only femtomoles (nanograms) of ABP-labeled enzymes.

123 stead of hours, consumes very little sample (nanogram or less), and provides on-line interface with u

124 , fused silica, and aluminum show respective nanogram per gram ranges of 3 +/- 0.1-5 +/- 0.3, 3 +/- 0

125 r of several hundred to several thousands of nanogram per gram.

126 are detrimental to aquatic organisms at sub-nanogram per liter concentrations, many studies have mea

127 ation of steroidogenesis gene transcripts at nanogram per liter concentrations.

128 on-fluorine bond and the need to achieve low nanogram per liter drinking water targets.

129 complex aqueous matrixes, demonstrating low nanogram per liter PAH detection limits and response tim

130 FCLs are presented as median nanogram per milligram.

131 Ralpha and sIL-13Ralpha2) are present in low nanogram per milliliter concentrations in the serum from

132 at picomolar concentrations of endotoxin and nanogram per milliliter doses of MD-2 and required prese

133 019 ng/dL (95% CI: -0.028, -0.009) with each nanogram per milliliter increase in maternal PFNA.

134 Protein quantification at or below the nanogram per milliliter level using liquid chromatograph

135 proaches for the determination of CsA at low nanogram per milliliter levels in rat plasma was examine

136 ion were achieved for urine samples, and low nanogram per milliliter levels were found in whole blood

137 ion (LOD) and limit of quantitation (LOQ) at nanogram per milliliter levels, corresponding to a conce

138 ocalin) typically circulate in plasma at low nanogram per milliliter levels.

139 ound to be in the picogram per milliliter to nanogram per milliliter range for MS1 and MS2 acquisitio

140 determination of (R,S)-propranolol at a low nanogram per milliliter region was partially validated w

141 Although mice have nanogram per milliliter serum levels of soluble (s) IL-1

142 measured in maternal serum during pregnancy (nanograms per gram lipid) and complete 7-year follow-up

143 ts of detection in the single to hundreds of nanograms per gram regime; isotope ratio accuracy and pr

144 ine mammals were on the order of hundreds of nanograms per gram tissue, which are some of the highest

145 omparing homes in the highest concentration (nanograms per gram) tertile to those with no detections,

146 tially exposing local populations to tens of nanograms per hour (e.g., octinoxate and methamphetamine

147 inary concentration or mass excretion rates (nanograms per hour and nanograms per kilogram per hour B

148 mass excretion rates (nanograms per hour and nanograms per kilogram per hour BW) were assessed in sam

149 c acid and perfluorooctane sulfonate) (0.023 nanograms per kilograms per day) was mapped from 212 mar

150 reported values as either nondetects or low nanograms per liter in rivers.

151 Only a few nanograms per liter of ethynodiol diacetate and desogest

152 vels would need to reach tens or hundreds of nanograms per liter to achieve a therapeutic dose.

153 25 pg/mL or more for NTproBNP (to convert to nanograms per liter, multiply by 1.0).

154 [56.8] vs 137.8 [83.4] pg/mL; to convert to nanograms per liter, multiply by 1; P = .10), complicati

155 field concentrations of tens to hundreds of nanograms per liter.

156 Already at a few nanograms per litre, these hormones can trigger endocrin

157 ssed both as nanograms per milliliter and as nanograms per microgram of total IgA or IgG.

158 detection (LOD) ranging from 0.002 to 0.008 nanograms per milliliter (ng/mL) and 0.005 to 0.017 ng/m

159 picograms per milliliter (pg/ml) to several nanograms per milliliter (ng/ml).

160 IgA and IgG in saliva were expressed both as nanograms per milliliter and as nanograms per microgram

161 in mouse serum with the sensitivity to a few nanograms per milliliter and secreted proteases by tumor

162 min/sample for the determination of ara-C at nanograms per milliliter in mouse plasma was partially v

163 PFAS plasma levels and ADHD [per natural log nanograms per milliliter increase: PFOS RR = 0.87 (95% C

164 CI: 0.82, 1.16)] or autism [per natural log nanograms per milliliter increase: PFOS RR = 0.92 (95% C

165 lowering the limit of detection (LOD) to the nanograms per milliliter level (i.e., LODs based on the

166 lated with recurrence (hazard ratio, 0.9 per nanograms per milliliter of PSA; 95% confidence interval

167 n facilitate analysis of peptides in the low nanograms per milliliter range.

168 imonabant in mouse plasma samples at the low nanograms per milliliter region in support of a pharmaco

169 all biomarkers with LODs on the order of low nanograms per milliliter to low picograms per milliliter

170 nsitivity for enabling quantification of low nanograms per milliliter to sub-naograms per milliliter

171 Limits of quantitation as low as several nanograms per milliliter were obtained for nicotine, cot

172 tection of the SAP glycoprotein at levels of nanograms per milliliter with a reproducibility value lo

173 The maximum NaF concentrations (nanograms per milliliter) in the choroid/retina after PS

174 d fT4 levels according to concentrations (in nanograms per milliliter) of six PFAS chemicals modeled

175 e 56- and 64-residue proteins (IC(50) ~ 0.16 nanograms per milliliter).

176 nanograms per milliliter; IC(80) 1.5 to 34.5 nanograms per milliliter).

177 n human plasma at trace levels (picomolar or nanograms per milliliter).

178 iologically relevant detection limits of low nanograms per milliliter, and RSD values of less than 5%

179 higher relative to patients without therapy (nanograms per milliliter, mean [95% confidence interval]

180 physiologically relevant detection limits of nanograms per milliliter.

181 for the drugs was from tens of picograms to nanograms per milliliter.

182 lution can be estimated down to fractions of nanograms per milliliter.

183 nhibitory concentration (IC(50)) 0.3 to 11.1 nanograms per milliliter; IC(80) 1.5 to 34.5 nanograms p

184 k ranged from a few tens of picograms to low nanograms per million of cells.

185 ntly toxic to kill fish at concentrations of nanograms per ml and, after accumulation in filter-feedi

186 RvD1 and RvD5 (nanograms per mouse) each reduced bacterial titres in bl

187 and reported in micrograms per kilogram and nanograms per puff, respectively, for easy comparison.

188 mM), NDMA can reach amounts of thousands of nanograms per tablet.

189 n one of the foaming drinking water wells at nanogram-per-liter concentrations.

190 , and the effect on fish reproduction at sub-nanogram-per-liter levels should prompt further research

191 ol), and struck flint (benzyl mercaptan), at nanogram-per-liter levels.

192 for the remarkable barrier-sparing effect of nanogram-per-milliliter concentrations of TGF-beta1 when

193 simple immunoassay capable of detecting sub-nanogram-per-milliliter quantities of various analytes i

194 ralized virus infection in Vero cells at the nanogram-per-milliliter range.

195 viral infection at concentrations below the nanograms-per-milliliter level, and we determined a stru

196 Peaks were detected at the low nanogram (pmol) level and peak areas were linear from 1

197 nterferences, (3) minimal sample volumes and nanogram protein amounts, (4) possibility to run several

198 However, reading DNA sequence from sub-nanogram quantities is impractical owing to inefficient

199 the optimization of HPLC conditions so that nanogram quantities of A2E can be detected from extracts

200 he DART heater temperature of 500 degrees C, nanogram quantities of benzo[e]pyrene (BeP) deposited on

201 (EP-ESI-MS), is shown to enable analysis of nanogram quantities of collected particles (from aerosol

202 ic acid can be quantitated by degradation of nanogram quantities of DNA followed by capillary gel ele

203 in primitive settings for the genotyping of nanogram quantities of DNA present in blood, dried and s

204 rofiling 5mC at single-base resolution using nanogram quantities of DNA.

205 dred samples can be assayed in an afternoon, nanogram quantities of enzyme can be characterized witho

206 Here we demonstrate that nanogram quantities of full-length recombinant APOL1 ind

207 three sensitive assays capable of detecting nanogram quantities of GAGs in biological samples.

208 conventional CAP, Bio-CAP can be applied to nanogram quantities of genomic DNA and in a magnetic for

209 ure microdissection is sufficient to isolate nanogram quantities of high-quality RNA.

210 bility to detect phosphorylation events from nanogram quantities of immunoprecipitated material, whic

211 The harmonics can be detected in vivo from nanogram quantities of iron within 5s.

212 e GC/combustion/IRMS technique requires only nanogram quantities of leucine with similar precision en

213 SCD mice were systemically challenged with nanogram quantities of LPS to trigger lung vasoocclusion

214 low frequencies (a few per Gigabase pair) in nanogram quantities of nonradioactive, genomic DNA by di

215 tive and reliable method for determining low nanogram quantities of oleamide in biological fluids.

216 and phosphorylation status information from nanogram quantities of protein cell lysate.

217 The method is rapid and sensitive with low-nanogram quantities of protein detected in the biologica

218 activated T cell cultures, and injection of nanogram quantities of recombinant IL-16 (rIL-16) into n

219 Nanogram quantities of rough-type LPS mixtures from Neis

220 recorded over 500-fold increases, such that nanogram quantities of starting material could be amplif

221 The present study assessed the ability of nanogram quantities of topically applied purified toxic

222 Here we report that RvE1 and PD1 in nanogram quantities promote phagocyte removal during acu

223 Here we provide evidence that RvE1, in nanogram quantities, promoted the resolution of inflamma

224 toxic to Argentine ants in extremely small (nanogram) quantities and is efficiently transferred from

225 Most important, very small (nanogram) quantities of this material neutralized 70-100

226 teristics, which enabled unique detection of nanogram quantity of analytes using photoacoustic spectr

227 say for the detection of proteins in the low nanogram range (4 ng) is described.

228 ogram sensitivity and linear response over a nanogram range allows trace quantitative measurements of

229 Detection limits down to the low nanogram range are obtained.

230 s immense potential to sense citrinin in sub-nanogram range by visual inspection in an inexpensive ye

231 Detection limits are in the low nanogram range for full-scan, programmed cone voltage sp

232 a benchtop mass spectrometer and in the low nanogram range using a portable ion trap MS.

233 tion and quantification limits in the single nanogram range were achieved when analyzing standards de

234 its of detection in the high picogram to low nanogram range were obtained for the compounds analyzed,

235 sections, equivalent to a sample mass in the nanogram range, and could thus pave the way for biomarke

236 t provides excellent detection limits in the nanogram range.

237 ensitive ELISA with a sensitivity in the low nanogram range.

238 germinating alfalfa seed exuded QACs in the nanogram range.

239 roscopic particles from explosives up to the nanogram range.

240 ionally potent, neutralizing 50% of virus at nanogram-range antibody concentration.

241 ompliant systems with masses of the order of nanograms, rendering them susceptible to optical forces.

242 every few seconds) and mass resolution (700 nanogram resolution).

243 cation kit showed promise for genotyping sub-nanogram samples.

244 eening throughput of 1 Hz working at the low nanogram scale.

245 ction mixture per second, working on the low-nanogram scale.

246 ena by measuring in situ mass changes on the nanogram scale.

247 n system capable of effectively working with nanogram scales of lysate digests.

248 oles for selected-ion monitoring), while low nanogram sensitivity was attained for proteins derived f

249 With a hundred nanograms starting plasmid DNA from pNL1, we were able t

250 ized a nanoproteomic workflow that we termed Nanogram TMT Processing in One Tube (NanoTPOT).

251 of individual protein complexes often yields nanogram to low-microgram amounts of protein, which pose

252 lly precludes the application samples in the nanogram to low-microgram range.

253 le mass spectrometry run, is compatible with nanogram to microgram amounts of cell lysate.

254 arious classes of biological small RNAs from nanogram to microgram amounts of total RNA without an am

255 Nanogram to microgram quantities of organic material dep

256 ple for automated multistep syntheses at the nanogram to microgram scale, could be generalized to a r

257 gments, the protocol takes 4-16 h to produce nanogram to microgram yields, depending on the complexit

258 Observed levels ranged from a nanogram to micrograms of NCA.

259 ver 3 orders of magnitude of deposited mass (nanograms to greater than micrograms).

260 C/MS) analysis of animal sera containing low nanograms to low micrograms per milliliter of PEGylated

261 Ten nanograms tumor necrosis factor-alpha per ml and 10 ng I

262 revealed at unprecedented 10 nM levels (1.3 nanograms), while Tyr and L-DOPA required 500 nM concent