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1 cidation of new molecules down to only a few nanomole.
2 ion for concentrations as low as few tens of nanomoles.
3 the detection threshold of approximately 10 nanomoles.
4 pecific biomolecules at the level of tens of nanomoles.
7 at bind to the HIV-1(BaL) gp120 protein with nanomole affinity were isolated from a RNA library by th
8 rolling-circle amplification, that produces nanomole amounts of single-stranded oligonucleotides per
11 low as a few picomoles to as high as several nanomoles can be determined in a microtiter plate in 10-
12 onstant was 1.9 mM, the maximum flux was 8.9 nanomoles/cm2 per hour, and the apparent Na+ :L-lactate
13 asurements are shown to be feasible even for nanomole concentrations of a membrane-associated peptide
16 trations of CoQ10 in the choroid was 27+/-16 nanomoles/g dry choroid for donors younger than 30 age a
17 ors younger than 30 years of age and 24+/-13 nanomoles/g dry retina for donors older than 80 years of
18 entration of CoQ10 in the retina was 42+/-11 nanomoles/g dry retina for donors younger than 30 years
20 le of large and very fast pressure drops (<1 nanomole, >2,500 atmospheres and <0.7 microseconds).
21 on was dose dependent, with injections of 10 nanomoles having virtually no effect to a maximum loss o
22 uantitating isothiocyanates (R-N=C=S) at the nanomole level is based on the observation that the high
23 m) of 73 +/- 9 microM, V(max) of 2.0 +/- 0.1 nanomoles/min per milligram protein, and K(d) of 0.44 +/
24 = 33 +/- 8 microM and V(max) = 0.26 +/- 0.03 nanomoles/min per square centimeter), energy independent
25 a potential diagnostic dose (25 mg/kg or 455 nanomoles Mn(2+)/kg; ~2 orders of magnitude lower than t
27 sured as the log of histidine revertants per nanomole of amine, log m, in Salmonella typhimurium TA 9
35 per square centimeter) and oxidized 33 to 45 nanomoles of ascorbate over 1 hour in the absence of oxy
36 lid-state NMR spectra for several to tens of nanomoles of beta-amyloid fibrils and ubiquitin in 1-2 d
37 phic peaks 15 s wide and containing up to 30 nanomoles of carbon was quantitatively converted to CO2
40 ively detected at micromolar concentrations (nanomoles of target) using resistive pulse sensing, conf
41 of less abundant phenolic conjugates down to nanomoles of trapped amounts of metabolite corresponding
43 cific activity (SA, in counts per minute per nanomole) of serum all-trans ((3)H)retinol in all mice e
47 esters in the shoots was determined to be 74 nanomoles per kilogram fresh weight as measured by isoto
48 ose (in millimoles per liter), C-peptide (in nanomoles per liter), hemoglobin A1c (as a percentage) a
49 stosterone level (>=150 ng/dL; to convert to nanomoles per liter, multiply by 0.0347) until progressi
50 nto high TT levels (>46 ng/dL [to convert to nanomoles per liter, multiply by 0.0347] for age <50 yea
52 low SHBG levels (<2.85 mug/mL [to convert to nanomoles per liter, multiply by 10.53]) as established
53 deficient, less than 12 ng/mL (to convert to nanomoles per liter, multiply by 2.496); insufficient, 1
55 5 [0.43] mug/dL, respectively [to convert to nanomoles per liter, multiply by 27.588]; beta = 0.18; P
56 , 12.3 mug/dL to 16.5 mug/dL) (to convert to nanomoles per liter, multiply by 29.6); 20.7 mug/dL for
57 s of 15.00 microg/L or higher (to convert to nanomoles per liter, multiply by 5.675) were assumed to
58 The PuO(2) + H(2)O reaction rate is 0.27 nanomoles per meter squared per hour at 25 degrees C; th
59 ecific activity was approximately 600 to 700 nanomoles per milligram protein per minute, and the late
60 scently labeled peptides are on the order of nanomoles per millimeter of length of monolith material
61 ranging from low picomoles per mol (ppt) to nanomoles per mol (ppb), depending on location and compo
63 gnal-to-noise ratio spectra were acquired on nanomole quantities of a protein in cells in minutes.
64 o)resorcinol assay of Hunt et al. to measure nanomole quantities of Co(2+), Ni(2+), and Cu(2+) as wel
67 m to the formazan enables the measurement of nanomole quantities of glyoxylate in an assay that is am
69 reagents (ChemBeads) enable the delivery of nanomole quantities of solid chemical reagents efficient
72 H NMR spectra can be acquired for microgram (nanomole) quantities of trace impurities in a complex sa
74 ed for concentrations in the low picomole to nanomole range, with correlation coefficients of R(2) >
79 be candidates were initially prepared on a 4 nanomole scale and could be tested directly from crude r
81 ration was enabled by the discovery of novel nanomole scale compatible automation friendly C-N coupli
82 g method for chemical reagents on micro- and nanomole scale prevents the full utilization of reaction
83 lity was demonstrated at the sub-milligram / nanomole scale with only a few hours of acquisition time
86 ers multiple analogues from a single lead at nanomole-scale amounts as DMSO-d(6) stock solutions with
87 ication of frontrunner drug candidates using nanomole-scale amounts of lead compounds for structure-a
88 a variety of experiments including automated nanomole-scale couplings between an OAC derived from riv
89 throughput LSF of covalent inhibitors at the nanomole-scale level can be an auspicious approach in im
91 Here, we have performed a high-throughput nanomole-scale synthesis campaign (nanoSAR) by late-stag
92 identify (13)C NMR signals in samples at the nanomole-scale that arise from Cl-substituted (13)C by e
95 cific H-isotope compositions of acetate with nanomole sensitivity, enough to enable analyses of envir
96 ree systems, 100 microM 22:6OOH induced 74.7 nanomoles superoxide per milligram plasma membrane prote
97 :6OOH-activated PMNs produced 11.10 +/- 0.68 nanomoles superoxide, and production was suppressed 72%
98 ns, fMLP induced production of 34.6 +/- 2.77 nanomoles superoxide, and RPP inhibited 60% of productio
99 exes present in quantities as small as a few nanomoles (tens of micrograms for the observed component
100 te antigen (HLA)/peptide combinations in the nanomole to picomole range with minimal run time, reconc
101 eported methods (typically around US$ 20 per nanomole total oligonucleotides produced) and is dominat