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1 opposite direction (FAST) or was unaltered (NATURAL).
2 incorporate thymidine analogs along with the natural A, T, G and C bases during DNA synthesis, which
6 nhance the global combined anthropogenic and natural aerosol indirect effect by -0.63 W m(-2) Our obs
10 comparisons level the playing field between natural and artificial intelligence, so that we can sepa
13 derstand and control crystallization in both natural and engineered systems, which occurs in complex
14 ant factor in determining the role of DOM in natural and engineered systems, yet there is still consi
17 cological tracking data, we analyze multiple natural and experimental ecosystems (marine plankton, in
18 s suggest the importance of considering both natural and human factors in coastal zone defense policy
21 using a manually curated list of viruses and natural and symptomatic hosts, we found that virus CUB t
24 the relative contributions of anthropogenic, natural, and internally-driven decadal variability of gl
27 ironmentally-friendly production, the use of natural antifungal compounds extracted by emerging techn
29 nctional metagenomics approaches to identify natural biocatalysts for novel chemical transformations.
38 study, we examined the antiviral activity of natural compounds against the following influenza virus
39 d leads for possible new drug candidates and natural compounds upon bioinformatics drug repurposing a
42 temperatures elevated to 1.8 degrees C above natural conditions or both treatments in combination ove
44 yping is without doubt useful to predict the natural course of disease, to determine pharmacotherapy
47 d that the antibody bound to TNFR2 through a natural cross-linking surface and that T(reg) cell expan
49 on on NK cells is associated with diminished natural cytotoxicity but enhanced antibody-dependent cel
51 ew have accounted for forest degradation and natural disturbances-processes that occur without forest
52 ve over decadal timescales, the emergence of natural drivers of loss presents an immediate challenge
53 uggest the potential of solenopsins as novel natural drugs against neglected parasitic diseases cause
54 where growing human populations and stressed natural ecosystems are at significant risk to such pheno
56 ntibodies (mAbs) isolated from a survivor of natural EEEV infection with potent (<20 pM) inhibitory a
61 d suggest avenues for further integration of natural enemy ecology and integrated pest management.
63 es of biological control programs, including natural enemy selection, efficacy testing and quantifica
65 ad convergence of animal phenotypes to their natural environment is well-established, there is a lack
66 otor responses.SIGNIFICANCE STATEMENT In our natural environment, our senses are continuously flooded
69 are important for the nitrogen cycle in both natural environments and wastewater treatment plants.
71 ven mercury (Hg) transformation processes in natural environments, thermodynamics and kinetics of div
74 e systems, on the other hand, aimed at using natural enzymes to improve circuit performance, although
75 s reached a plateau at the level of the best natural enzymes, suggesting that we have exhausted the p
77 ornia's 2013-2016 extraordinary drought as a natural experiment, we studied four co-occurring woodlan
81 test whether one potential stressor-limited natural food sources in cities-can explain reduced avian
82 the climate system to both anthropogenic and natural forcing rather than any intrinsic internal oscil
84 at maximum climate mitigation potential from natural forest regrowth is 11 per cent lower than previo
86 d discuss how their study, in the context of natural freely moving behaviors, could advance models of
90 Growing literature linking unconventional natural gas development (UNGD) to adverse health has imp
95 al and computational study that exploits the natural genetic variation across five closely related sp
99 stands to lose both from present exposure to natural hazards, and future climate-driven shifts in the
103 The link between liver fibrosis and the natural history of COVID-19 should be evaluated in futur
104 spective cohort study helps characterize the natural history of DCM, provides insight into the host i
109 oor, but because of its relative rarity, the natural history remains incompletely characterized.
114 ecause of the few animal models available as natural hosts that are compatible with such studies.
115 ar to that of symptomatic hosts than that of natural hosts, supporting a general deleterious effect o
117 s of ILC2s have been described: steady-state natural ILC2s and inflammatory ILC2s, which are elicited
118 ure adequate 11-cis-retinal production under natural illuminances that can span ten orders of magnitu
119 e pretrained on glioblastoma MRI, instead of natural images, to determine if performance was improved
122 ting that Tim-3 expression might represent a natural immune mechanism limiting viral spread.IMPORTANC
126 e 4 to 6 log-folds stronger affinity for its natural inhibitor, serine acetyltransferase (SAT), as co
134 al/phenotypic changes induced in CD8(+) T or natural killer (NK) cells by MTEX or non-MTEX were compa
135 virus (ECTV; the agent of mousepox) and that natural killer (NK) cells in CL13-infected mice are redu
136 s well as DARA-induced depletion of CD38high natural killer (NK) cells resulting in crippled antibody
137 cells with unique immune properties, such as natural killer (NK) cells, NKT cells, gammadelta T cells
139 ors and chimeric antigen receptor-expressing natural killer and T cells, the overall survival of pati
141 c constraint in macrometastases triggered by natural killer cell depletion suggests a dynamic interpl
142 rapy had an increased abundance of activated natural killer cells and a newly identified CD3(-)CD68(+
144 dritic cells, and CD8 T lymphocytes and CD57 natural killer cells in the ALNs(-) were factors associa
145 he number of tumor-infiltrating CD8(+) T and natural killer cells, slowed tumor growth, and improved
146 eeks of infection, for example proliferating natural killer cells, which potentially may associate wi
154 Applying techniques from computer vision and natural language processing, we 'un-box' our models usin
155 spired by the discontinuous frost pattern on natural leaves, here we report findings on the condensat
156 ocytes to the gut is mediated by MAdCAM, the natural ligand of alpha(4)beta(7) that is expressed on g
159 This study has therefore evolved current natural marine snow protocols to generate 'artificial' m
161 nction threats, identifying the relevance of natural mating patterns for conservation management.
162 esponding specific surface area (SSA) of the natural metal-(hydr)oxide fraction is ~350-1400 m(2)/g,
163 apply digital rock physics to reticulite, a natural mineral with a strong analogy to synthetic open-
165 ese processes and establishes Naegleria as a natural model system for studying microtubule-independen
169 r, current technologies have been limited to natural nucleic acids and are often incompatible with po
170 ery little about how evolutionary processes (natural or artificial) might have modified underlying ne
173 rotein 1 (NRG1) is a large (> 60-amino-acid) natural peptide ligand for the ErbB protein family membe
176 argue that this arises as a consequence of a natural phase transition in the dynamic self-organizatio
182 ry has remained an outstanding challenge for natural polypeptides, building blocks of life, which are
183 predator-prey relationship, we investigated natural populations of nematodes and NTF that we found t
184 determinants of gene expression evolution in natural populations, we analyzed the transcriptome from
187 varying selection maintain polymorphisms in natural populations; and provided important case studies
189 Fungal bioluminescence is a fascinating natural process, standing out for the continuous convers
192 ted resource using a synthetic-bioinformatic natural product (syn-BNP) approach, which relies on bioi
193 decades, traditional drug discovery has used natural product and synthetic chemistry approaches to ge
196 which can be selectively reduced to give the natural product framework without recourse to stepwise U
200 uaternary carbon is a predominant feature of natural product structures and has been associated with
202 the collective and concise syntheses of the natural products (-)-microthecaline A, (-)-leubehanol, (
204 rated of the late-stage functionalization of natural products and drug molecules, stereospecific synt
205 are' sugars feature prominently in bioactive natural products and pharmaceuticals, including antivira
209 ass of macrocyclic, heavily modified peptide natural products that are unified by the presence of a s
210 e alkaloids represent an important family of natural products with a wide-spectrum of biological acti
212 he prevalence of aryl thioether in bioactive natural products, functional materials, agrochemicals, a
213 ile receptors (CRs) to detect poorly soluble natural products, thereby defining a form of contact-dep
221 surrounding male gametophytes and acts as a natural protector of pollen grains against various envir
223 and stability of the material as compared to natural pyrite was evidenced, as deduced from its charac
225 ane landfalls, prompting questions about the natural range in variability of hurricane activity that
227 tle reproductive success at higher and lower natural ranges in temperature, when blowfly larvae are m
230 FMNR involves farmers selecting and managing natural regeneration on their fields, while keeping them
231 vian species wherein they maintain a diverse natural reservoir, posing a risk to humans through the o
234 tious political issue, the valuation of this natural resource is sometime viewed as a strategy to avo
236 obal warming, water scarcity and diminishing natural resources negatively impacts food security.
237 which is shrinking as a result of declining natural resources, climate change, and the growing world
239 nt quantitative microstructural results from natural samples and thermodynamic modeling indicating th
241 uld unify cognitive science with the broader natural sciences, but leave key elements of cognition an
244 pared genetic architecture and the effect of natural selection on these blood phenotypes between popu
246 of past transposition increase signatures by natural selection, we performed a laboratory evolution e
252 relevance of AGO4, RdR1, RdR2, and DCL3 in a natural setting was revealed when plants individually si
255 Estimated RBA for Pb in both remediated natural soils and Pb-mineral spiked soils were reduced b
256 nderstanding the strength and erodibility of natural soils, and other polydisperse particulates that
258 have evolved not only to aid the analysis of natural sounds but to enhance the sensitivity of hearing
260 to protect different species is to preserve natural soundscapes of ecosystems to which species have
261 d vadose zone soil and exposed to 3 years of natural South Carolina, USA, meteorological conditions.
263 ry effect of the presence of Quaker beans in natural specialty coffee beverage and, consequently, to
269 well as with the phylogeny of A. oligospora natural strains, calculated after assembly and annotatio
271 s and screened 231 FDA-approved oncology and natural substance drugs included in two NCI drug librari
272 flippase MurJ, we find that addition of the natural substrate lipid-II results in the formation of a
273 that the Michaelis complex of the enzyme and natural substrate undergoes which align the nucleophile
274 e stimulated interest as synthetic models of natural systems and integral components of photodynamic
275 ur ability to understand and predict Earth's natural systems is lagging behind our ability to monitor
276 statistics are ubiquitously observed in many natural systems, and the development of efficient method
280 ecognition via affinity-enhanced versions of natural TCRs (e.g., immune-mobilizing monoclonal T cell
284 ection is an important evolutionary force in natural tree populations and suggest that management int
285 rogressing plaques that expressed markers of natural Tregs derived from the thymus, Tregs in regressi
286 al generation; to study enzyme function with natural, unnatural and CF(2)-labelled post-translational
290 se plants reveal a trade-off between VTE and natural variation in chorismate metabolism explained by
291 contributes to the robustness of TC through natural variation in GI and ZTL alleles found on the Cap
294 arcinoic acid (GA or delta-T3-13'COOH), is a natural vitamin E metabolite that has preliminarily been
296 udy show that the impact of acidification of natural waters on Fe availability will be much more pron
297 t loss process for CDOM absorption in sunlit natural waters, where it can regulate the biota's exposu