ライフサイエンスコーパス: natural menopause

1 ad repeat hormone measures and experienced a natural menopause.

2 o were premenopausal at baseline and reached natural menopause.

3 my with the changes observed up to and after natural menopause.

4 icant independent predictor of the timing of natural menopause.

5 teristics were associated with the timing of natural menopause.

6 /ethnicity were associated with later age at natural menopause.

7 sed to assess factors associated with age at natural menopause.

8 reported increased mortality risk with early natural menopause.

9 ) was associated with higher risk of earlier natural menopause.

10 e the associations between PFAS and incident natural menopause.

11 ith shorter LTL, especially among women with natural menopause.

12 ause period exhibited higher risk of earlier natural menopause.

13 can be challenging, and more severe than at natural menopause.

14 enetically predicted LTL with earlier age at natural menopause.

15 causal relationships between LTL and age at natural menopause.

16 lescent to midlife weight change with age at natural menopause.

17 e at menopause than women who have undergone natural menopause; 2) reliability declines with time sin

18 Among women who had undergone a natural menopause, 44% reported their age at menopause w

19 By 2008, 1,769 women had reached natural menopause, 77 women had a hysterectomy with ovar

20 Survey (NHANES) to describe trends in age at natural menopause, age at menarche, and reproductive lif

21 herefore, we aimed to evaluate risk of early natural menopause among 107,817 members of the Nurses' H

22 vestigated factors influencing the timing of natural menopause among 95,704 women with a mean age of

23 perfluorohexane sulfonate (PFHxS) and age at natural menopause among women 20-65 years of age in NHAN

24 used to examine the relation between age at natural menopause and all-cause and cause-specific morta

25 1.36, 95% CI 1.15-1.61; P = 0.0003); age at natural menopause and endometrioid carcinoma (OR per yea

26 sk associated with MHT in women experiencing natural menopause and for late age at natural menopause

27 ed to assess the associations between age at natural menopause and incidence and timing of cardiovasc

28 Age at natural menopause and self-reported menopausal symptoms

29 in those observational studies had undergone natural menopause and were treated for the relief of men

30 Aging, natural menopause, and cancer treatments such as surgica

31 with age, duration of breastfeeding, age at natural menopause, and duration of estrogen use differed

32 vely with early age at menarche, late age at natural menopause, and total length of ovulation span, b

33 ear follow-up, and 13-year follow-up; age at natural menopause; and menopausal symptoms.

34 g, assessed using normal variation in age at natural menopause (ANM) in about 200,000 women of Europe

35 uman SYCP2L locus are associated with age at natural menopause (ANM).

36 tein-coding variation associated with age at natural menopause (ANM).

37 served population distribution of the age at natural menopause (ANM).

38 continuing treatment at the time of expected natural menopause, approximately age 50 years.

39 Age at menarche and age at natural menopause are associated with causes of substant

40 stimate hazard ratios (HRs) for the onset of natural menopause as a function of age and serum PFC lev

41 nts previously associated with normal age at natural menopause as a quantitative trait (QT) were also

42 abortion; 1.32 (1.15, 1.51) (p = 0.008) for natural menopause at <47 compared to 50 years; 1.12 (1.0

43 53 (95% confidence interval: 0.58, 4.07) for natural menopause at age < or =45 years compared with >

44 sed women were 50% more likely to experience natural menopause at any given age (hazard ratio = 1.49,

45 Risks of natural menopause before age 50 years were elevated for

46 ion person-years, 2041 women reported having natural menopause before the age of 45 y.

47 erapy, who never smoked, and who experienced natural menopause between the ages of 40 and 54 years.

48 Body mass index is associated with age at natural menopause, but the influence of weight change re

49 portance: As many as 10% of women experience natural menopause by the age of 45 years.

50 nt in the fetus and be associated with early natural menopause (ENM) for offspring.

51 Early natural menopause (ENM) has been associated with reduced

52 ars (subtracting age at menarche from age at natural menopause), from 36.1 years among women born bet

53 ho underwent bilateral oophorectomy prior to natural menopause had a higher risk of restless legs syn

54 The timing of natural menopause has implications for several health en

55 cell NHL (based on 67 cases) than women with natural menopause (hazard ratio = 1.51, 95% confidence i

56 risk of BCC was associated with late age at natural menopause (hazard ratio [HR] for >/= 55 years v

57 ces (PFAS) have been associated with earlier natural menopause; however, the underlying mechanisms ar

58 had reported their menopause status, age at natural menopause (if postmenopausal), and cardiovascula

59 or factors measured at study entry on age of natural menopause in 185 healthy US women.

60 ed survival analyses to estimate the risk of natural menopause in 4,210 DES-exposed versus 1,829 unex

61 ts support the hypothesis that the timing of natural menopause is driven by a combination of genetic,

62 on and Mendelian randomization, older age at natural menopause is related to lower concentrations of

63 Age at natural menopause is related to several health outcomes,

64 The effect of PFAS on natural menopause may be partially explained by variatio

65 ne withdrawal (such as following surgical or natural menopause) may impact the efficacy of progestero

66 Early natural menopause (menopause before age 45 years) was re

67 versely associated with XFG/XFGS compared to natural menopause (MVHR = 0.37; 95% CI: 0.15, 0.92; FDR-

68 ardiovascular disease (CVD) before and after natural menopause (NM), hysterectomy with at least 1 ova

69 seven traits related to reproductive (age at natural menopause, number of children, age at first chil

70 Relative to non-Latina Whites, natural menopause occurred earlier among Latinas (US-bor

71 Natural menopause occurred earlier in women with subsequ

72 eline, postmenopausal includes patients with natural menopause or that induced by ovarian suppression

73 5), and also among women with earlier age at natural menopause (P for trend<0.05).

74 Early natural menopause, rather than decreasing risk of SLE be

75 or women who experienced premature or early natural menopause should be considered for hormonal trea

76 ing association between parity and timing of natural menopause, surgical menopause, and premenopausal

77 ciation between early-life events and age at natural menopause, the authors used Cox proportional haz

78 Early natural menopause, the cessation of ovarian function pri

79 ere fitted to examine the relation of age at natural menopause to lifestyle and anthropometric factor

80 K Biobank, 2,231 (1.14%) of whom reported at natural menopause under the age of 40 years.

81 ffect of women's lifestyles on the timing of natural menopause using data from a cross-sectional ques

82 encing natural menopause and for late age at natural menopause warrant further investigation.

83 Overall, median age at natural menopause was 51.4 years, after adjustment for s

84 During follow-up through 2017, timing of natural menopause was assessed biennially, and VMS were

85 Age at natural menopause was categorised as premenopausal or pe

86 The Kaplan-Meier estimate for median age of natural menopause was earlier in women residing in neigh

87 demographic and lifestyle factors to age at natural menopause was examined in seven US centers and f

88 Surgical versus natural menopause was inversely associated with XFG/XFGS

89 Overall, natural menopause was most common by study end (57.2%),

90 ls (RR, 1.39; 95% CI, 1.07 to 1.81), whereas natural menopause was not.

91 ed with rate of hysterectomy, and time since natural menopause was positively associated with serum P

92 For age at natural menopause, we identified 13 associated SNPs (P =

93 rospective cohort study of 6040 women with a natural menopause were followed up at 3-y intervals over

94 re all independently associated with earlier natural menopause, while parity, prior use of oral contr

95 isk was most increased among women reporting natural menopause who used MHT for 10 or more years vers

96 d 50,678 women (21,511 who had experienced a natural menopause) who were 40-98 years of age at study

97 n between age at menarche, parity and age at natural menopause with 249 metabolic traits in over 65,0

98 her PFAS concentrations had shorter times to natural menopause, with a relative survival of 0.82 (95%