ライフサイエンスコーパス: natural peptide

1 to one of the mimotope peptides than to the natural peptide.

2 anced antibacterial activity relative to the natural peptide.

3 ional space that could not be reached by the natural peptide.

4 nd demonstrate a 3-fold enhancement over the natural peptide.

5 e, alpha(v)beta5, as effectively as does the natural peptide.

6 ve recently been explored as mimics of these natural peptides.

7 all protein-like molecules designed to mimic natural peptides.

8 kbone oligomers ("foldamers") that fold like natural peptides.

9 robial properties of certain natural and non-natural peptides.

10 CD4 T cells that recognized three different natural peptides.

11 liquid chromatography of both synthetic and natural peptides.

12 tructures in the solid/solution phase, as in natural peptides.

13 play procedure provides a generic way to non-natural peptide adhesion domains, which not only mimic n

14 AT(1) receptors and similar affinity for the natural peptide agonist angiotensin II.

15 oupled receptors is critically important for natural peptide agonist binding and action.

16 e complex conformational space explored by a natural peptide agonist when binding to its GPCR.

17 Natural peptide agonists of corticotrophin-releasing fac

18 Non-natural peptide analogs have significant potential for t

19 odified decamer is more immunogenic than the natural peptide and a candidate for peptide-based melano

20 etically encoded cell-based synthesis of non-natural peptide and depsipeptide macrocycles is an outst

21 owed that it had no effect on the binding of natural peptide and nonpeptidyl ligands of this receptor

22 structural elements, as the backbones of all natural peptides and proteins are composed of amide bond

23 The ability of natural peptides and proteins to influence the formation

24 ically bind amyloid fibrils formed from many natural peptides and proteins.

25 lonal antibodies, small synthetic molecules, natural peptides, and aptamers.

26 gle-molecule fingerprinting of synthetic and natural peptides, and show discrimination, within a hete

27 Natural peptide antibiotics are part of host innate immu

28 Synthetic peptides modeled after natural peptide antibiotics interfere with microbial mem

29 With these in hand, non-natural peptides are being produced for evaluation in a

30 whereby approximately 1.5 million novel and natural peptides are fabricated on the scaffold present

31 ules governing conformational preferences in natural peptides are poorly understood, and consequently

32 However, these natural peptides as well as their beta-peptide analogues

33 Synthetic and natural peptide assemblies can possess transport or cond

34 cent protein of Aequorea victoria (GFP) is a natural peptide chromophore without substrate or cofacto

35 EPI-X4, a natural peptide CXCR4 antagonist, shows potential for tr

36 is attributable to C-terminal amidation of a natural peptide derived from osteocalcin.

37 ated T-cells displayed a perturbation of the natural peptides displayed by HLA-B*57:01.

38 The natural peptides FMRFamide and FLRFamide only activated

39 Melittin, a natural peptide found in bees, has been shown to induce

40 Natural peptides from animal venoms effectively modulate

41 The overall strategy of identifying natural peptides from islet beta-cells opens up new aven

42 oating luminescent gold nanoparticles with a natural peptide, glutathione, and the simplest stable am

43 These results suggest that the natural peptide histogranin may be a novel adjunct in ne

44 lly equal to or potentially more potent than natural peptides in stimulating CTL responses; therefore

45 RAP1/2), and N-terminally extended model and natural peptides in their free and HLA-B*0801-bound form

46 en extensively investigated in synthetic and natural peptides, including by nanosecond kinetic studie

47 compound, a 150-fold higher potency than the natural peptide inhibitor (IC50 2.9 muM).

48 lutamate-containing 27-residue peptide, is a natural peptide inhibitor of the N-methyl-d-aspartate (N

49 ural basis for the domain selectivity of the natural peptide inhibitors of ACE, bradykinin potentiati

50 tures of these segments, we designed two non-natural peptide inhibitors that block aggregation.

51 Epitope discovery from natural peptide libraries is a promising route to subuni

52 ontrast, 50% of the peptides selected from a natural peptide library, in which phage display segments

53 ghts into the conformation and dynamics of a natural peptide ligand docked to a Family B G protein-co

54 rotein 1 (NRG1) is a large (> 60-amino-acid) natural peptide ligand for the ErbB protein family membe

55 elucidate the structural basis of binding a natural peptide ligand to a family A G protein-coupled r

56 The recently identified natural peptide ligand, tuberoinfundibular peptide of 39

57 with the action mechanism of the receptor's natural peptide ligand.

58 evident that the carboxyl-terminal region of natural peptide ligands bind to the amino-terminal domai

59 ed receptors that bind preferentially to the natural peptide ligands substance P (SP) and neurokinin

60 ed receptors that bind preferentially to the natural peptide ligands substance P and neurokinin A, re

61 The binding mode of natural peptide ligands to the Y(5) G protein-coupled re

62 Besides natural peptide ligands, screening of random peptide lib

63 ed methodology facilitates the generation of natural peptides, like Magainin 2, and the derivatizatio

64 The natural peptide-major histocompatibility complex (pMHC)

65 TCR engagement with natural peptide-MHC class I agonist resulted in the same

66 natural polymers that mimic the functions of natural peptides or proteins in their ability to direct

67 pitope motif (QKRAA) was as effective as the natural peptide p135H sequence for inducing arthritis.

68 esults indicate that along with the abundant natural peptides p2Ca and p2Cb, the QL9 and other OGDH p

69 e constructing bicyclic peptides from simple natural peptide precursors.

70 ver, such an approach uses zero knowledge of natural peptide-receptor interactions that might have be

71 compound pharmacology, their application to natural peptides rich in disulfide bridges and active on

72 that the hydrolytic stability of functional, natural peptide sequences can be improved by two orders

73 Natural peptide sequences ligate to dirhodium centers th

74 When JG-365 was converted into the natural peptide substrate for molecular dynamic simulati

75 We have identified the natural peptide target of a CTL clone that recognizes th

76 Synthetic and natural peptides that act as nonselective melanocortin r

77 Due to the limited availability of natural peptides, the properties of human epithelial def

78 The conformation of the natural peptide [Thr6]-bradykinin, Arg1-Pro2-Pro3-Gly4-P

79 The natural peptide [Thr6]-bradykinin, Arg1-Pro2-Pro3-Gly4-P

80 For instance, the natural peptide Tilapia Piscidin 4 (TP4) exhibits potent

81 We used a set of natural peptides to explore the specificity of dissolved

82 olvents, which differs from that observed in natural peptide turns.

83 Analysis of the disulfide bridges of a natural peptide tx3c from C. textile and synthetic pepti

84 The fragmentation of natural peptides using dynamic collision-induced dissoci

85 against multiple citrullinated synthetic and natural peptides was recently developed and used to stai

86 In total, 244 natural peptides were identified ex vivo as possible sub

87 ne somatostatin, a pharmaceutically relevant natural peptide, which contains a Trp-based type II' bet

88 Thus, scLCDV1-VILP is a natural peptide with specific antagonist properties on I

89 red mice were used to determine which of the natural peptides with natriuretic peptide-like structure

90 ithin its N terminus a motif conserved among natural peptides with potent immunomodulatory and antimi

91 It is also proposed that natural peptides with the ability to promote biominerali

92 iple analysis steps to locate and quantitate natural peptides within a single experiment and to align

93 novel algorithms for detecting signatures of natural peptides within a single LC-MS measurement and c