ライフサイエンスコーパス: necrotizing enterocolitis

1 2, periventricular leukomalacia >grade 1, or necrotizing enterocolitis).

2 with LOS and 164 unaffected controls (no LOS/necrotizing enterocolitis).

3 ty, bronchopulmonary dysplasia, and surgical necrotizing enterocolitis).

4 nary dysplasia, severe cerebral lesions, and necrotizing enterocolitis).

5 en microbes and host immune elements such as necrotizing enterocolitis.

6 n of ISCs contributes to the pathogenesis of necrotizing enterocolitis.

7 ncovered, such as the transfusion-associated necrotizing enterocolitis.

8 s such as intestinal atresias, volvulus, and necrotizing enterocolitis.

9 s enteritis, inflammatory bowel disease, and necrotizing enterocolitis.

10 r periventricular leukomalacia; and death or necrotizing enterocolitis.

11 eath were serious respiratory conditions and necrotizing enterocolitis.

12 responses seen in developing intestine as in necrotizing enterocolitis.

13 migration of enterocytes during experimental necrotizing enterocolitis.

14 resection in preterm infants with perforated necrotizing enterocolitis.

15 specific inflammatory bowel diseases such as necrotizing enterocolitis.

16 posed to initial colonizing bacteria develop necrotizing enterocolitis.

17 outcome, and preventable measures related to necrotizing enterocolitis.

18 nation of urine may allow early detection of necrotizing enterocolitis.

19 oefficients than those from patients without necrotizing enterocolitis.

20 ch as bacterial sepsis, viral infection, and necrotizing enterocolitis.

21 most effective interventions reducing severe necrotizing enterocolitis.

22 very low birthweight are at serious risk for necrotizing enterocolitis.

23 ent of often concomitant conditions, such as necrotizing enterocolitis.

24 eterm infant microbiota and protects against necrotizing enterocolitis.

25 achieve the rate from the best quartile for necrotizing enterocolitis.

26 of late-onset sepsis, growth faltering, and necrotizing enterocolitis.

27 d incidence of neonatal bacterial sepsis and necrotizing enterocolitis.

28 h postnatal intestinal pathologies including necrotizing enterocolitis.

29 re intraventricular hemorrhage, and death or necrotizing enterocolitis.

30 ities in infants who did and did not develop necrotizing enterocolitis.

31 rain was common to all infants who developed necrotizing enterocolitis.

32 on, a process that may lead to diseases like necrotizing enterocolitis.

33 am, urinary tract, or cerebrospinal fluid or necrotizing enterocolitis.

34 ch were profoundly depleted in newborns with necrotizing enterocolitis.

35 ther this practice reduces the prevalence of necrotizing enterocolitis.

36 so a trend towards a diminished incidence of necrotizing enterocolitis.

37 3 to 1.00; P=0.045) and an increased rate of necrotizing enterocolitis (10.4% vs. 8.0%; relative risk

38 (17.5% [95% CI, 16.5%-18.6%]), and death or necrotizing enterocolitis (19.3% [95% CI, 18.1%-20.4%]).

39 ratory distress (40.5% vs 48.7%; P=.04), and necrotizing enterocolitis (2.3% vs 5.8%; P=.03) were les

40 Overall, 8.9% (890/9956) of infants had necrotizing enterocolitis, 2.4% (238/9957) had early-ons

41 there were increases in deaths attributed to necrotizing enterocolitis (30 [95% CI, 27 to 34] vs. 23

42 urvivors (23.3%, 19.1%, and 11.7%), death or necrotizing enterocolitis (48.1%, 37.1%, and 32.5%), and

43 hat occurred significantly less was death or necrotizing enterocolitis (73.5% with exposure to antena

44 Premature neonates are at risk of necrotizing enterocolitis, a disease almost exclusively

45 prolonged the survival of newborn mice with necrotizing enterocolitis, a severe pathology in preterm

46 sed sample of 30 566 VLBW infants, 1879 with necrotizing enterocolitis, according to the level of car

47 rsity gut microbiome in neonates who develop necrotizing enterocolitis after day of life 40.

48 r prevention, diarrhea, Helicobacter pylori, necrotizing enterocolitis, allergy, and inflammatory bow

49 odds ratios of 9.7 (95% CI, 2.9 to 32.2) for necrotizing enterocolitis and 1.7 (95% CI, 1.1 to 2.7) f

50 tive epithelium occurs in hemorrhagic shock, necrotizing enterocolitis and conditions resulting in in

51 The fear of necrotizing enterocolitis and feeding intolerance are ma

52 ve been implicated as a pathogenic factor in necrotizing enterocolitis and inflammatory bowel disease

53 bowel diseases (controls) and 8 infants with necrotizing enterocolitis and measured levels of S100A8

54 administered to premature infants to prevent necrotizing enterocolitis and neonatal sepsis.

55 premature newborns has been shown to prevent necrotizing enterocolitis and reduce all-cause mortality

56 ts, where the virus has been associated with necrotizing enterocolitis and severe and persistent diar

57 es had suspected (n = 5) or definite (n = 7) necrotizing enterocolitis, and 10 neonates without necro

58 dities before PDA closure, including sepsis, necrotizing enterocolitis, and a dependence on mechanica

59 ory bowel disease, irritable bowel syndrome, necrotizing enterocolitis, and a variety of other disord

60 e, confirmed or suspected late-onset sepsis, necrotizing enterocolitis, and cerebral palsy.

61 aturity, severe intraventricular hemorrhage, necrotizing enterocolitis, and chronic lung disease amon

62 nguage and motor scores, in-hospital growth, necrotizing enterocolitis, and death.

63 complications (sepsis, chronic lung disease, necrotizing enterocolitis, and intraventricular hemorrha

64 onary dysplasia, retinopathy of prematurity, necrotizing enterocolitis, and periventricular leukomala

65 ety of inflammatory diseases such as asthma, necrotizing enterocolitis, and sepsis.

66 e, death, death in the first postnatal week, necrotizing enterocolitis, and severe bronchopulmonary d

67 s, hearing loss, bronchopulmonary dysplasia, necrotizing enterocolitis, and severe retinopathy of pre

68 om BEC on premature infants with and without necrotizing enterocolitis, and successfully provided a t

69 to the clinical phenotype of Crohn disease, necrotizing enterocolitis, and, perhaps, intestinal mani

70 f necrotizing enterocolitis, the severity of necrotizing enterocolitis, and/or bacterial sepsis.

71 in mortality (AOR, 0.98; 95% CI, 0.70-1.37), necrotizing enterocolitis (AOR, 0.88; 95% CI, 0.65-1.20)

72 g were also associated with a higher risk of necrotizing enterocolitis (ARR, 1.20; 95% CI, 1.16-1.24;

73 iventricular or intraventricular hemorrhage, necrotizing enterocolitis, aspiration, retinopathy of pr

74 irth weights less than 1500 g and perforated necrotizing enterocolitis at 15 pediatric centers to und

75 Notably, ELGAN/ELBW infants developing necrotizing enterocolitis before day 14 had higher expre

76 Necrotizing enterocolitis (Bell stage 2 or 3) occurred i

77 ry outcome was a composite outcome of death, necrotizing enterocolitis (Bell stage II or higher), ret

78 The composite primary outcome included necrotizing enterocolitis (Bell's stage IIa or higher),

79 Infants with necrotizing enterocolitis born into midlevel hospitals (

80 he 10th centile, bronchopulmonary dysplasia, necrotizing enterocolitis, brain injury, and earlier neo

81 ry, kidney failure, intracranial hemorrhage, necrotizing enterocolitis, bronchopulmonary dysplasia, b

82 to early ibuprofen treatment with respect to necrotizing enterocolitis, bronchopulmonary dysplasia, o

83 rematurity, intracranial hemorrhage, sepsis, necrotizing enterocolitis, bronchopulmonary dysplasia, o

84 he following morbidities: late-onset sepsis, necrotizing enterocolitis, bronchopulmonary dysplasia, p

85 infants is associated with a reduced risk of necrotizing enterocolitis but an increased risk of late-

86 y distress or failure, pulmonary hemorrhage, necrotizing enterocolitis, catastrophic intracranial hem

87 All-cause mortality, severe necrotizing enterocolitis, culture-proven sepsis, feedin

88 Mental development was most impaired by necrotizing enterocolitis (d = -0.40; P < .001) and meni

89 Motor development was most impaired by necrotizing enterocolitis (d = -0.66; P < .001).

90 up to 36 weeks of postmenstrual age included necrotizing enterocolitis, death, and growth faltering (

91 Necrotizing enterocolitis, defined as Bell stage 2 or gr

92 e type of operation performed for perforated necrotizing enterocolitis does not influence survival or

93 ptation to small-bowel resection (SBR) after necrotizing enterocolitis expands absorptive surface are

94 heart disease surgery, medical and surgical necrotizing enterocolitis, extremely low birth weight, v

95 ondary outcomes included morbidities such as necrotizing enterocolitis, feed intolerance, and extraut

96 he underlying diagnoses: intestinal atresia, necrotizing enterocolitis, gastroschisis, and midgut vol

97 ipient host, such as reduction in sepsis and necrotizing enterocolitis, have been reported for premat

98 ydrocephalus (HR 17.3 95% CI 13.8-21.6), and necrotizing enterocolitis (HR 18.8 95% CI 16.7-21.2) com

99 th (HR, 2.49; 95% CI, 1.69-3.67), grade 2b-3 necrotizing enterocolitis (HR, 7.41; 95% CI, 5.14-10.7),

100 against chronic intestinal inflammation and necrotizing enterocolitis in animal models.

101 emerging pathogen that causes meningitis and necrotizing enterocolitis in infants.

102 Here we show that necrotizing enterocolitis in neonate mice is accompanied

103 adults, and may be associated with neonatal necrotizing enterocolitis in premature infants.

104 given enterally may reduce the incidence of necrotizing enterocolitis in preterm infants.

105 diabetes, nonalcoholic fatty liver disease, necrotizing enterocolitis in very low birth weight infan

106 who survived more than 12 hours, were severe necrotizing enterocolitis, infection, bronchopulmonary d

107 ospital morbidities were assessed, including necrotizing enterocolitis, infection, intracranial hemor

108 ed with 17P had significantly lower rates of necrotizing enterocolitis, intraventricular hemorrhage,

109 Necrotizing enterocolitis is a devastating inflammatory

110 Necrotizing enterocolitis is a major cause of death and

111 Perforated necrotizing enterocolitis is a major cause of morbidity

112 Necrotizing enterocolitis is a relatively common disorde

113 Necrotizing enterocolitis is an overwhelming gastrointes

114 Necrotizing enterocolitis is the leading cause of death

115 levance was suggested, as TLR4 activation in necrotizing enterocolitis led to reduced proliferation a

116 Infections and necrotizing enterocolitis, major causes of mortality and

117 rstanding some of these important aspects of necrotizing enterocolitis may help improve the outlook o

118 hemorrhage, bronchopulmonary dysplasia, and necrotizing enterocolitis, most therapeutic approaches h

119 ne (n = 1538), sepsis (n = 1922), sepsis and necrotizing enterocolitis (n = 279), or meningitis with

120 schisis (n=5), intestinal atresia (n=5), and necrotizing enterocolitis (n=4).

121 utcomes included all-cause mortality, severe necrotizing enterocolitis (NEC) (Bell stage II or more),

122 Necrotizing enterocolitis (NEC) affects up to 10% of pre

123 apan are reported to have a low incidence of necrotizing enterocolitis (NEC) among countries, and the

124 fusions are associated with a higher risk of necrotizing enterocolitis (NEC) among extremely low-birt

125 LNT were shown to protect neonatal rats from necrotizing enterocolitis (NEC) and are good therapeutic

126 t gut microbiota alterations associated with necrotizing enterocolitis (NEC) and feeding intolerance

127 Although the incidence of neonatal necrotizing enterocolitis (NEC) and the mortality stemmi

128 d blood cell (RBC) transfusion and anemia to necrotizing enterocolitis (NEC) are conflicting.

129 Necrotizing enterocolitis (NEC) as COD increased between

130 n that has been associated with outbreaks of necrotizing enterocolitis (NEC) as well as infant sepsis

131 Necrotizing enterocolitis (NEC) brain injury is mediated

132 Necrotizing enterocolitis (NEC) causes acute intestinal

133 Necrotizing enterocolitis (NEC) continues to be a major

134 Necrotizing enterocolitis (NEC) develops in response to

135 Necrotizing enterocolitis (NEC) has long remained a sign

136 and inflammation in an experimental model of necrotizing enterocolitis (NEC) in neonatal rats.

137 ant manifestation of severe diseases such as necrotizing enterocolitis (NEC) in neonates or bowel wal

138 The authors evaluated the risk of necrotizing enterocolitis (NEC) in very low birth weight

139 ponse may have a role in the pathogenesis of necrotizing enterocolitis (NEC) in very preterm infants.

140 Necrotizing enterocolitis (NEC) is a common and often fa

141 Necrotizing enterocolitis (NEC) is a common, potentially

142 Necrotizing enterocolitis (NEC) is a devastating disease

143 Necrotizing enterocolitis (NEC) is a devastating disease

144 Necrotizing enterocolitis (NEC) is a devastating disease

145 Necrotizing enterocolitis (NEC) is a devastating disease

146 Necrotizing enterocolitis (NEC) is a devastating gastroi

147 Neonatal necrotizing enterocolitis (NEC) is a devastating gastroi

148 Necrotizing enterocolitis (NEC) is a devastating gastroi

149 Necrotizing enterocolitis (NEC) is a devastating inflamm

150 Necrotizing enterocolitis (NEC) is a devastating intesti

151 Necrotizing enterocolitis (NEC) is a disease of neonatal

152 Necrotizing enterocolitis (NEC) is a disease of prematur

153 Necrotizing enterocolitis (NEC) is a gastrointestinal co

154 Neonatal necrotizing enterocolitis (NEC) is a major cause of morb

155 Necrotizing enterocolitis (NEC) is a major cause of morb

156 Necrotizing enterocolitis (NEC) is a major cause of neon

157 Necrotizing enterocolitis (NEC) is a serious consequence

158 Necrotizing enterocolitis (NEC) is a severe disease of t

159 Necrotizing enterocolitis (NEC) is a severe disease that

160 Necrotizing enterocolitis (NEC) is a severe gastrointest

161 Necrotizing enterocolitis (NEC) is an idiopathic, inflam

162 Necrotizing enterocolitis (NEC) is an inflammatory bowel

163 Necrotizing enterocolitis (NEC) is an inflammatory disea

164 Necrotizing enterocolitis (NEC) is an inflammatory intes

165 Experimental necrotizing enterocolitis (NEC) is characterized by circ

166 Necrotizing enterocolitis (NEC) is characterized by inte

167 Necrotizing enterocolitis (NEC) is one of the most serio

168 Necrotizing enterocolitis (NEC) is the leading cause of

169 Necrotizing enterocolitis (NEC) is the leading cause of

170 Necrotizing enterocolitis (NEC) is the leading cause of

171 Necrotizing enterocolitis (NEC) is the leading cause of

172 Necrotizing enterocolitis (NEC) is the most common and s

173 Necrotizing enterocolitis (NEC) is the most common gastr

174 Necrotizing enterocolitis (NEC) is the most common gastr

175 Necrotizing enterocolitis (NEC) is the most common gastr

176 Necrotizing enterocolitis (NEC) is the most common gastr

177 Necrotizing enterocolitis (NEC) is the most devastating

178 rentiation and is involved in development of necrotizing enterocolitis (NEC) of the immature intestin

179 underwent initial laparotomy or drainage for necrotizing enterocolitis (NEC) or isolated intestinal p

180 actors that regulate enterocyte apoptosis in necrotizing enterocolitis (NEC) remain incompletely unde

181 The pathophysiology of necrotizing enterocolitis (NEC) remains poorly understoo

182 r is the consequence of intestinal injury in necrotizing enterocolitis (NEC) remains unknown.

183 Necrotizing enterocolitis (NEC) requiring surgical inter

184 iseases of gut inflammation such as neonatal necrotizing enterocolitis (NEC) result after an injury t

185 gative pathogen associated with the cases of necrotizing enterocolitis (NEC) that result from formula

186 the susceptibility of premature newborns to necrotizing enterocolitis (NEC) through mechanisms that

187 ation of oxygen therapy; presence of PDA and necrotizing enterocolitis (NEC) were important risk fact

188 Necrotizing enterocolitis (NEC), a cause of death among

189 the proinflammatory cascade, is activated in necrotizing enterocolitis (NEC), a devastating condition

190 t of lung disease in the setting of neonatal necrotizing enterocolitis (NEC), a life-threatening gast

191 Necrotizing enterocolitis (NEC), a major cause of morbid

192 ure and role of the intestinal leukocytes in necrotizing enterocolitis (NEC), a severe disease affect

193 Necrotizing enterocolitis (NEC), a severe intestinal inf

194 Premature neonates are predisposed to necrotizing enterocolitis (NEC), an idiopathic, inflamma

195 y result in antibiotic resistance, fungemia, necrotizing enterocolitis (NEC), and mortality.

196 ing bronchopulmonary dysplasia (BPD), severe necrotizing enterocolitis (NEC), and neonatal brain inju

197 CU morbidities, including late-onset sepsis, necrotizing enterocolitis (NEC), and severe intraventric

198 y infections, otitis media, gastroenteritis, necrotizing enterocolitis (NEC), and sudden infant death

199 lk feeding is associated with lower rates of necrotizing enterocolitis (NEC), but an understanding of

200 thought to contribute to the pathogenesis of necrotizing enterocolitis (NEC), but it is unknown wheth

201 ns, including respiratory distress syndrome, necrotizing enterocolitis (NEC), early-onset sepsis, lat

202 the widespread use of plain films to detect necrotizing enterocolitis (NEC), it is considered a time

203 astrointestinal diseases, including neonatal necrotizing enterocolitis (NEC), the leading cause of de

204 Necrotizing enterocolitis (NEC), the leading cause of ga

205 reast milk (HBM) attenuates the incidence of necrotizing enterocolitis (NEC), which remains a leading

206 . perfringens and the preterm infant disease necrotizing enterocolitis (NEC), with specific NEC cases

207 ession, which can lead to the development of necrotizing enterocolitis (NEC)--a devastating inflammat

208 possible pregnancy-related risk factors for necrotizing enterocolitis (NEC)-associated deaths during

209 ons of prematurity, including spontaneous or necrotizing enterocolitis (NEC)-associated intestinal pe

210 bile acids (BAs) may mediate development of necrotizing enterocolitis (NEC).

211 factor (EGF) in prophylaxis and treatment of necrotizing enterocolitis (NEC).

212 infants in order to reduce the incidence of necrotizing enterocolitis (NEC).

213 rategies or feeding interventions to prevent necrotizing enterocolitis (NEC).

214 of preterm infants with and without neonatal necrotizing enterocolitis (NEC).

215 e associated with the deadly infant disease, necrotizing enterocolitis (NEC).

216 is supposedly associated with development of necrotizing enterocolitis (NEC).

217 diseases characterized by ISC loss including necrotizing enterocolitis (NEC).

218 riate analysis, SL mortality predictors were necrotizing enterocolitis (NEC; surgical odds ratio, 5.9

219 necrosis due to bowel ischemia, infarction, necrotizing enterocolitis, neutropenic colitis, volvulus

220 Necrotizing enterocolitis occurred in 105 of 764 control

221 Necrotizing enterocolitis occurred in 24 of 136 infants

222 Late-onset invasive infection or necrotizing enterocolitis occurred in 32% of infants (19

223 Necrotizing enterocolitis occurred in 4.2% of infants (1

224 Necrotizing enterocolitis occurred in 70 of 1394 infants

225 Necrotizing enterocolitis occurred less frequently in th

226 Necrotizing enterocolitis occurred more frequently in in

227 re was one hospital death from postoperative necrotizing enterocolitis on postoperative day 71 and fo

228 CI, 0.58-0.78) and the combined outcomes of necrotizing enterocolitis or death and severe intraventr

229 dio-pulmonary bypass, as well as in neonatal necrotizing enterocolitis or persistent ductus arteriosu

230 r retinopathy of prematurity and surgery for necrotizing enterocolitis or spontaneous intestinal perf

231 nography, severe retinopathy of prematurity, necrotizing enterocolitis, or late-onset sepsis) by 36 w

232 of serious infection (sepsis or meningitis), necrotizing enterocolitis, or mortality during the first

233 e were no differences in time to full feeds, necrotizing enterocolitis, or other key neonatal morbidi

234 periventricular leukomalacia, proven sepsis, necrotizing enterocolitis, or perinatal death).

235 ystic periventricular leukomalacia, surgical necrotizing enterocolitis, or stage 3 or greater retinop

236 Interestingly, we find that necrotizing enterocolitis patients also exhibit decrease

237 itating severe thrombocytopenia (eg, sepsis, necrotizing enterocolitis, perinatal asphyxia, and the i

238 bsence of radiographic evidence of extensive necrotizing enterocolitis (pneumatosis intestinalis), ge

239 ntral nervous system injury decreased, while necrotizing enterocolitis-related deaths increased.

240 Infants with necrotizing enterocolitis represent a high-risk subgroup

241 he liberal vs restrictive thresholds groups, necrotizing enterocolitis requiring surgical interventio

242 The majority of babies with necrotizing enterocolitis respond to nonsurgical managem

243 de 3-4, cystic periventricular leukomalacia, necrotizing enterocolitis, retinopathy of prematurity st

244 ites of death or bronchopulmonary dysplasia, necrotizing enterocolitis, retinopathy of prematurity, a

245 ure of major neonatal morbidities, including necrotizing enterocolitis, retinopathy of prematurity, b

246 It also decreases the prevalence of necrotizing enterocolitis, sepsis, and intraventricular

247 PN significantly affects risk of mortality, necrotizing enterocolitis, sepsis, chronic lung disease,

248 onary hemorrhage but not with differences in necrotizing enterocolitis, severe bronchopulmonary dyspl

249 No differences in rates of necrotizing enterocolitis, severe bronchopulmonary dyspl

250 Urine from neonates with necrotizing enterocolitis show significantly higher CT a

251 etinopathy of prematurity requiring surgery, necrotizing enterocolitis, spontaneous intestinal perfor

252 The incidence of necrotizing enterocolitis stage II or more (0 vs 5%) and

253 pathy of prematurity (stage 3 or higher), or necrotizing enterocolitis (stages 2-3).

254 nical complications of prematurity including necrotizing enterocolitis, systemic infections and bronc

255 The frequencies of air leaks and necrotizing enterocolitis, the duration of respiratory s

256 ng anaerobic bacteria may reduce the rate of necrotizing enterocolitis, the severity of necrotizing e

257 In addition, reports regarding the risk for necrotizing enterocolitis, the utility of lactate as an

258 The former effect occurs in necrotizing enterocolitis; the latter influence is seen

259 ria in premature infants are associated with necrotizing enterocolitis, underscoring the critical rol

260 izing enterocolitis, and 10 neonates without necrotizing enterocolitis underwent routine upper gastro

261 icient of urine from patients with suspected necrotizing enterocolitis was 26.0 HU +/- 3.4, and that

262 +/- 3.4, and that in patients with definite necrotizing enterocolitis was 71.0 HU +/- 18.8.

263 ere intraventricular hemorrhage and death or necrotizing enterocolitis was lowest among infants born

264 The occurrence of necrotizing enterocolitis was significantly higher in th

265 of the study, just 28.6% of the infants with necrotizing enterocolitis were born into high-level, hig

266 CT attenuation coefficients in neonates with necrotizing enterocolitis were significantly different f

267 ple, odds ratio = 3.33; P value = 0.0007 for necrotizing enterocolitis), while TPN2.0 recommendations

268 Chorioamnionitis, necrotizing enterocolitis, white matter injury on crania

269 Urine from another 13 neonates without necrotizing enterocolitis who did not receive iohexol wa

270 6 HU +/- 3.9, and that from neonates without necrotizing enterocolitis who underwent upper gastrointe

271 ntly different from that in patients without necrotizing enterocolitis who underwent upper gastrointe

272 in all affected rabbits included erosive and necrotizing enterocolitis with adherent bacterial rods,