ライフサイエンスコーパス: neonatal

1 ve association between maternal glycemia and neonatal AA was observed across the whole range of mater

2 Fetal or neonatal abnormalities were classified as a major birth

3 S aureus colonization by 90 days, defined as neonatal acquisition of an S aureus strain that was the

4 Secondary outcomes included neonatal acquisition of any S aureus strain and neonatal

5 Additional outcomes included neonatal admission, mode of delivery, perineal laceratio

6 We calculated neonatal (age 0-27 days), post-neonatal (age 28-364 days

7 We calculated neonatal (age 0-27 days), post-neonatal (age 28-364 days), child (age 1-4 years), and u

8 ere AKI, and 0.81 (95% CI, 0.77 to 0.86) for neonatal AKI.

9 Paternal low protein diet modified F1 neonatal and adult offspring renin-angiotensin system ac

10 in the human population and can be fatal in neonatal and immunocompromised individuals.

11 National and regional incidence of neonatal and infantile endogenous endophthalmitis and co

12 cidence, and risk factors for development of neonatal and infantile endogenous endophthalmitis.

13 tial to substantially enhance the quality of neonatal and pediatric critical care.

14 n isotope partitioning between the maternal, neonatal, and placental compartments were identified.

15 onditioning was used to assess the impact of neonatal anesthesia exposure on behavioral learning in a

16 bling the immature active-stem cell niche of neonatal animals.

17 Neonatal APPs varied with perinatal environmental factor

18 A convenience sample with neonatal asphyxia were monitored for twenty hours in the

19 ty in LQTS with atypical features, including neonatal atrioventricular block.

20 petent Tg(+) juveniles exhibited spontaneous neonatal bacterial infections with robust mucoinflammato

21 levated DNA methylation was also detected in neonatal BAT and brown progenitors.

22 vaccination status influenced the effect of neonatal BCG vaccination.

23 ry lumen closes rapidly at birth, preventing neonatal blood loss, whereas the umbilical vein remains

24 Compared with neonatal-born neurons, old adult-born neurons had greate

25 Neonatal brachial plexus injury (NBPI) causes disabling

26 aracterized by visceroautonomic dysfunction (neonatal bradycardia/apnea, feeding problems, hyperactiv

27 suggest reciprocal escalation of immune and neonatal brain injury in a subset of ASD that may benefi

28 All respiratory parameters were worse after neonatal bronchopulmonary dysplasia, and respiratory fun

29 Second, neonatal-but not adult-microglia express several extrace

30 Neonatal C-reactive protein was consistently associated

31 H therapies.Objectives: We hypothesized that neonatal cardiac magnetic resonance imaging (MRI) will c

32 These proliferative neonatal cardiomyocytes display a unique transcriptional

33 om electronic medical records of a level III neonatal care center in Germany and were collected betwe

34 ate dyads (356 [98%] with available data for neonatal care practices) in Nigeria, 760 (749 [99%]) in

35 e used to examine associations between these neonatal care practices, maternal and neonate characteri

36 6, [95% CI 177 to 2,014]) and admission to a neonatal care unit >=4 days occurred in 1.1% (24/2,280)

37 ssion models were used to relate measures of neonatal CB microstructure and childhood preterm behavio

38 Furthermore, Maf/Mafb neonatal cDKOs have decreased CINs and increased HINs, t

39 Biliary atresia (BA) is a devastating neonatal cholangiopathy that progresses to fibrosis and

40 hies in the differential diagnosis of severe neonatal cholestasis even in the absence of more typical

41 an established ciliopathy phenotype, severe neonatal cholestasis is rarely recognized as such.

42 ansfer of virus-specific antibodies into the neonatal circulation and protects against nHSV neurologi

43 ver-expression of Atoh1 and Gfi1 in cultured neonatal cochlear explants resulted in numerous ectopic

44 regeneration using gene transfer methods in neonatal cochlear explants, and in vivo in adult mice.

45 we show that cDC2s are abundant in the MZ of neonatal compared with adult mice.

46 is a significant risk factor for stillbirth, neonatal complications and adulthood morbidity.

47 With the aim of investigating the risk of neonatal complications, and the short- and long-term ris

48 oups (4,200, 16,800, 28,000 IU) vs. placebo, neonatal cord blood lead levels were 8.5% (95% CI: - 3.5

49 urological abnormalities (including abnormal neonatal cry, hypotonia, epilepsy, polyneuropathy, cereb

50 Neonatal CSF AVP concentrations were significantly lower

51 one resulted in significantly lower risks of neonatal death alone and stillbirth or neonatal death th

52 ere associated with higher relative risks of neonatal death and greater absolute rate differences in

53 rs a 100 g periviable live birth infant as a neonatal death has placed Ohio and the United States at

54 stational age and Apgar score on the risk of neonatal death is unknown.

55 ks of neonatal death alone and stillbirth or neonatal death than the use of placebo, without an incre

56 djusted life-years (DALYs) for fetal loss or neonatal death, low birthweight, moderate or severe mate

57 erinatal outcome (either maternal, fetal, or neonatal death, or severe morbidity for the mother or ba

58 and there were 36,485 infant deaths (25,110 neonatal deaths and 11,375 postneonatal deaths).

59 Progress in reducing maternal and neonatal deaths and stillbirths is impeded by data gaps,

60 An estimated 5.1 million stillbirths and neonatal deaths occur annually.

61 s could avert 41% of maternal deaths, 39% of neonatal deaths, and 26% of stillbirths, equating to 2.2

62 912 (98%) of 933 cases (180 stillbirths, 449 neonatal deaths, and 304 child deaths); two or more cond

63 s would avert 67% of maternal deaths, 64% of neonatal deaths, and 65% of stillbirths, allowing 4.3 mi

64 No study reported neonatal deaths, maternal morbidity, preterm births, or

65 l livebirths, stillbirths, miscarriages, and neonatal deaths.

66 eath attributed to underlying disease and no neonatal deaths.

67 admitted very-low-birthweight infants in our neonatal department.

68 e single murine dermal cell type, the innate neonatal-derived IL-17 producing gammadelta T (Tgammadel

69 Neonatal diabetes is caused by single gene mutations red

70 t of ATP and are now the primary therapy for neonatal diabetes mellitus caused by mutations in the ge

71 known mutations and sulfonylurea therapy in neonatal diabetes mellitus.

72 Neonatal diet has a large influence on child health and

73 The neonatal disease includes some hallmarks of macrophage a

74 ll carries a high burden of communicable and neonatal diseases, probably due to the weakness of healt

75 Malaria, lower respiratory infections, neonatal disorders, diarrhoeal diseases, and tuberculosi

76 light on the interconnectedness of these two neonatal disorders, holding potential for the discovery

77 All patients had neonatal/early-onset diabetes, severe microcephaly, and

78 Method (M2) uses a Neonatal EEG Analysis Toolbox (WU-NEAT).

79 rent practice of therapeutic hypothermia for neonatal encephalopathy, disability rates and the severi

80 The rate of decline in incidence of neonatal endogenous endophthalmitis was 4% from 2003 thr

81 Neonatal expansion was halted in mice conditionally defi

82 th diverse types of receptors, including the neonatal Fc receptor (FcRn) and Fcgamma receptors (Fcgam

83 Neonatal Fc receptor (FcRn) has a key role in the homeos

84 The neonatal Fc receptor (FcRn) that mediates IgG and albumi

85 The neonatal Fc receptor (FcRn) transports IgG across barrie

86 gG1 IC and formed a ternary complex with the neonatal Fc receptor (FcRn) under acidic conditions.

87 gagement with its cognate cellular recycling neonatal Fc receptor.

88 uscle actin in human adult dermal (HDFs) and neonatal fibroblasts (HFFs) mainly via TGF-beta canonica

89 tional studies including antigen-binding and neonatal fragment crystallizable (Fc) receptor (FcRn) bi

90 ride levels and renal triglyceride levels in neonatal G6pc -/- mice.

91 To investigate how neonatal gammadelta T cell repertoires are shaped by mic

92 oal was to determine the mechanisms by which neonatal GEN exposure causes implantation defects.

93 -day-old G6pc -/- mice serving as a model of neonatal GSD Ia.

94 on of gut-derived pathobionts in a dysbiotic neonatal gut and prevent these pathobionts from dissemin

95 tus, did not suggest a genomic signature for neonatal gut colonization.

96 The neonatal gut microbiome undergoes dynamic changes in res

97 ent effects of antibiotics on the developing neonatal gut microbiota needs to be precisely quantified

98 The results suggest disproportion between neonatal head circumference and weight may be a useful s

99 Neonatal herpes simplex virus (HSV) disease results in u

100 high risk for distress, in association with neonatal hippocampal connectivity and infant memory.

101 irmed a functional role for CD31 and CD54 in neonatal homeostatic extravasation.

102 implifies the regulatory programs that guide neonatal HSC/HPC ontogeny, but it creates heterogeneity

103 an 120,000 cells from pancreata of adult and neonatal human donors.

104 sis and alveolarization during recovery from neonatal hyperoxic injury.

105 ng altered learning/memory, hearing defects, neonatal hypotonia and decreased hippocampal volume.

106 der-Willi syndrome (PWS) is characterized by neonatal hypotonia, developmental delay and hyperphagia/

107 Neonatal hypoxic-ischaemic encephalopathy (HIE) is a lea

108 weeks postmenstrual age on a neonatal-sized, neonatal ICU-sited 1.5-T magnetic resonance (MR) scanner

109 lucidates the genetics of gene expression in neonatal immune cells, and aetiological origins of autoi

110 ed signaling pathways would make blocking of neonatal immune tolerance to retroviruses an achievable

111 ectivity controller 2 (vic2), that abrogates neonatal immune tolerance to retroviruses.

112 In combination with robust neonatal immunisation programmes, ongoing PMTCT efforts,

113 As (miRNAs), which play an important role in neonatal immunity.

114 e severe diseases, such as puerperal sepsis, neonatal infections, and necrotizing myometritis.

115 Neonatal injury also dampened the intrinsic membrane exc

116 g the neonatal period.SIGNIFICANCE STATEMENT Neonatal injury has lasting effects on pain processing i

117 Notably, neonatal injury reduced the strength of dynorphin-lineag

118 Indicators of the neonatal innate immune response are associated with risk

119 Mothers with babies in the neonatal intensive care unit (NICU) face a host of chall

120 e of death within 7 days or admission to the neonatal intensive care unit (NICU) with moderate-to-sev

121 of health care-associated infections in the neonatal intensive care unit (NICU).

122 Extended early antibiotic exposure in the neonatal intensive care unit is associated with an incre

123 ved ROP screening examinations at a level IV neonatal intensive care unit over a 7-year period.

124 uencing on stool swab samples collected from neonatal intensive care unit patients within 7 days of d

125 nal recordings during the baby's stay in the Neonatal Intensive Care Unit.

126 of hand antisepsis of healthcare workers in neonatal intensive care units may be associated with lon

127 streptococcus (GBS) is the leading cause of neonatal invasive disease worldwide.

128 totherapy is a standard treatment for severe neonatal jaundice to remove toxic bilirubin from the blo

129 Neonatal LDG may thus represent a distinct population th

130 UNC80 knockout mice are neonatal lethal.

131 x3 from the SAN and (cardiac) ganglia and in neonatal lethality.

132 lular signaling, development, and subsequent neonatal lethality.

133 Neonatal life marks the apogee of murine thymic growth.

134 The 2020 CoSTRs for neonatal life support are published either as new statem

135 The Neonatal Life Support Task Force generally determined by

136 , Pediatric Basic and Advanced Life Support, Neonatal Life Support, Resuscitation Education Science,

137 nsion of non-classical monocytes, and in the neonatal liver upon experimental expansion of these cell

138 mmadeltaT17 cells rapidly proliferate within neonatal lymph nodes and gut, where, upon entry, they up

139 educed in the lateral periodontium (gums) of neonatal Magel2-deficient mice compared to wild-type con

140 ated cardiomyocyte: studies in zebrafish and neonatal mammals have convincingly demonstrated the rege

141 Olfaction is critical for survival in neonatal mammals.

142 ere also collected according to maternal and neonatal medical records.

143 erapy targeting infections such as bacterial neonatal meningitis and is an important step for the con

144 Bacterial neonatal meningitis results in high mortality and morbid

145 Patients with the most severe form of MFS (neonatal MFS; nMFS) tend to have mutations that cluster

146 lar basis of the nearly complete recovery of neonatal mice after spinal cord injury, and suggest stra

147 In neonatal mice and cultured differentiating oligodendrocy

148 Depletion of microglia in neonatal mice disrupts this healing process and stalls t

149 Neonatal mice exhibit natural heart regeneration after m

150 PLZF(+) innate lymphocytes in germ-free (GF) neonatal mice is restored by colonization with a human c

151 Here we show that neonatal mice that lack the capacity to produce IgG are

152 ed that increased levels of IL-27 predispose neonatal mice to more severe infection during Gram-negat

153 Primary human AECs and neonatal mice were inoculated with RSV and murine Pneumo

154 Neonatal mice were transiently exposed to broad-spectrum

155 Mechanistically, this was explained in neonatal mice, in which long-chain, but not short-chain,

156 the absence of systemic disease in wild-type neonatal mice, thus mirroring the key features of human

157 tokine interleukin-27 (IL-27) is elevated in neonatal mice.

158 er than other B cell types and are sparse in neonatal mice.

159 eminating systemically and causing sepsis in neonatal mice.

160 secretion, and reduced diarrhea severity in neonatal mice.

161 ating LMC progenitor contribution to PLVs in neonatal mice.

162 t spinal cords prepared from male and female neonatal mice.

163 mpact on ciliogenesis in the hypothalamus of neonatal mice; through these effects they critically mod

164 Collectively, these data indicate that neonatal microbial colonization of the gut elicits conco

165 Our data identify that the neonatal microenvironment in combination with STAT5 is c

166 We transplanted either neonatal microglia or adult microglia treated with pepti

167 Although maternal and neonatal mitochondrial bioenergetics were positively cor

168 Neonatal morbidities are associated with long term neuro

169 and is the leading infectious cause of early neonatal morbidity and mortality in the United States.

170 of stillbirth(1) and is also associated with neonatal morbidity and mortality(2,3), impaired health a

171 ic infant, shoulder dystocia, and associated neonatal morbidity in low- and mixed-risk populations.

172 The risk of perinatal death and severe neonatal morbidity increases gradually after 41 weeks of

173 nsufficient data to analyze other markers of neonatal morbidity.

174 ds), shoulder dystocia, and other markers of neonatal morbidity.

175 on-induced preterm birth is a major cause of neonatal mortality and morbidity and leads to preterm pr

176 Preterm birth (PTB) is a major cause of neonatal mortality and morbidity, often triggered by cho

177 e is an important modifiable risk factor for neonatal mortality and morbidity.

178 an help to substantially reduce maternal and neonatal mortality and stillbirths in LMICs.

179 come countries, reductions in stillbirth and neonatal mortality have been slow.

180 ath and greater absolute rate differences in neonatal mortality in all gestational-age strata.

181 uring lockdown (p=0.0002), and institutional neonatal mortality increased from 13 per 1000 livebirths

182 onal age and calculate its impact on overall neonatal mortality rate over a 12-year period (1998-2009

183 Neonatal mortality rate per 1000 live births was 11.4.

184 Their proportion to the total neonatal mortality rate was 48.6%; out of 298 periviable

185 their outcomes (institutional stillbirth and neonatal mortality rate), and quality of intrapartum car

186 ital beds per 1,000 people) and performance (neonatal mortality rate).

187 tes and 10 minutes was associated with lower neonatal mortality than a stable Apgar score.

188 pollutant quintiles were compared; however, neonatal mortality was significantly associated with SO2

189 Preterm birth remains a common cause of neonatal mortality, with a disproportionately high burde

190 or child mortality than for neonatal or post-neonatal mortality.

191 5B protein expression, bacterial burden, and neonatal mortality.

192 mary outcome was fresh stillbirth and 28-day neonatal mortality.

193 erived primitive macrophage progenitors into neonatal mouse brains.

194 Molecular and functional maturation of neonatal mouse cardiomyocytes and human embryonic stem c

195 Regenerative capacity is robust in the neonatal mouse heart but is lost during postnatal develo

196 In contrast, the neonatal mouse heart can efficiently regenerate during t

197 otection against lethal CVA16 infection in a neonatal mouse model.

198 Here, using adult and neonatal mouse models of DM1, we show that intramuscular

199 Neonatal mouse models of RSV were employed, wherein mice

200 s potential peripheral targets of AVP in the neonatal mouse.

201 ractions including immune-epithelial PICs in neonatal murine lungs.

202 Inhibition of UA or IL-1beta during neonatal murine RSV infection decreased mucus production

203 Here, we identify regenerative factors in neonatal murine skin that transforms adult skin to regen

204 or efficient heart repair and function after neonatal myocardial infarction, and that cardiac deliver

205 rkar1 knock-out mouse embryonic fibroblasts, neonatal myocytes, or adult LV myocytes isolated from "r

206 We also tested the ability of neonatal NET-inhibitory factor (nNIF) to block NET forma

207 uideline was introduced in 2016 by the Wales Neonatal Network.

208 Significant changes in F2 neonatal offspring growth and tissue angiotensin-convert

209 e considered a poorer prognosis phenotype of neonatal-onset glaucoma.

210 nts with N-CEU were compared with those with neonatal-onset primary congenital glaucoma (N-PCG).

211 gaps were wider for child mortality than for neonatal or post-neonatal mortality.

212 is differentially associated with all-cause neonatal or postneonatal mortality, or specific causes o

213 regression models, showing no differences in neonatal or two-year outcomes by unit policy.

214 Yolk-sac macrophages of EMP origin produced neonatal osteoclasts that can create a space for postnat

215 Abnormal neonatal outcome was defined as abnormal exam and/or abn

216 aternal viremia predicts fetal infection and neonatal outcome.

217 r secondary outcomes focused on maternal and neonatal outcomes and decision quality.

218 imicrobials reviewed, adverse maternal/fetal/neonatal outcomes were not observed consistently.

219 fatty acids (FAs) are related to beneficial neonatal outcomes with DNA methylation proposed as a mec

220 al Delta9-THC exposure on fetal development, neonatal outcomes, and placental development.

221 to deliver normally to measure pregnancy and neonatal outcomes, with a subset sacrificed at E19.5 for

222 acted data on maternal, pregnancy, and fetal/neonatal outcomes.

223 e preventable, and their impact on fetal and neonatal outcomes.

224 eostatic, and developing skin, we identified neonatal papillary fibroblasts that form a transient reg

225 liciting protective antibodies to a specific neonatal pathogen represents an important host defence m

226 restores functional systemic circulation in neonatal patients with single ventricle congenital heart

227 Neonatal PCR testing, placental findings, and infant out

228 ded studies whose population of interest was neonatal, pediatric, trauma, or noncritically ill.

229 emia and offspring AA measured by MRI in the neonatal period and during the preschool years.

230 control group were stillborn or died in the neonatal period compared with 221 (15%) of 1447 infants

231 osahexaenoic acid supplementation during the neonatal period did not significantly improve bronchopul

232 xposure to broad spectrum antibiotics in the neonatal period is associated with persistent alteration

233 tex.SIGNIFICANCE STATEMENT Stroke during the neonatal period leads to long-term disabilities.

234 ve dynamics of GABAergic neurons during that neonatal period remain unknown.

235 g defense against bacterial pneumonia in the neonatal period, but the signals that guide pulmonary IL

236 nsates for the lack of MZ B cells during the neonatal period.

237 proportion developed fatal sepsis during the neonatal period.

238 g spinal cord, following injuries during the neonatal period.SIGNIFICANCE STATEMENT Neonatal injury h

239 AVPR1A throughout the neonatal periphery suggest roles for AVP in modulating p

240 his knowledge gap, we investigated fetal and neonatal pig pancreas at multiple, crucial developmental

241 ein (CRP) determination in serum and preterm neonatal plasma samples with sepsis suspicion.

242 Compared to adults, neonatal platelets showed enhanced sensitivity to thromb

243 Furthermore, neonatal pups were rendered resistant to RRV-mediated li

244 Unlike neonatal pups, late gestation fetuses proved to be resis

245 l and/or genetically manipulate cells in the neonatal rat and mouse brain.

246 e used primary OPCs in culture isolated from neonatal rat cortices of both sexes and young male and f

247 Here, we investigated the interaction of neonatal rat heart cells with engineered spider silk pro

248 bly, electrophysiology, and contractility of neonatal rat ventricular cardiomyocytes (NRVCMs) culture

249 Neonatal rat ventricular cardiomyocytes were infected wi

250 ion in CryAB(WT) and CryAB(R120G)-expressing neonatal rat ventricular cardiomyocytes.

251 of-function ETV1 RNA sequencing dataset from neonatal rat ventricular myocytes transduced with Etv1 s

252 In neonatal rats, CDC-9 P45 showed reduced rotavirus sheddi

253 rotavirus strain, CDC-9, in Caco-2 cells and neonatal rats.

254 Fc neonatal receptor (FcRn) was originally discovered as a

255 an internal region of fibrillin-1 called the neonatal region.

256 emental oxygen, neonatal ventilator use, and neonatal resection (p < 0.001).

257 advantages over face-mask ventilation during neonatal resuscitation in low-income countries, but whet

258 Previous treatments for neonatal ROP included peripheral laser ablation (n = 3),

259 natal acquisition of any S aureus strain and neonatal S aureus infections.

260 Intestinal tissues from neonatal S100-knockout mice had reduced levels of CX3CR1

261 thod for qualitative detection of CMV DNA in neonatal saliva samples.

262 in any of the other 6 clinical maternal and neonatal secondary outcomes.

263 e absence of controlled trials, treatment of neonatal seizures has changed minimally despite poor dru

264 d bumetanide added to phenobarbital to treat neonatal seizures in the first trial to include a standa

265 ed coverage of antibiotics for pneumonia and neonatal sepsis and of oral rehydration solution for dia

266 erials have emerged as a better platform for neonatal sepsis biomarkers detection.

267 tes an inflammatory cytokine response during neonatal sepsis by directly compromising control of bact

268 to identify major biomarkers associated with neonatal sepsis including Serum Amyloid A (SAA), C - rea

269 deaths across the world are occurred due to neonatal sepsis infections.

270 ptibility and improve infectious outcomes in neonatal sepsis.

271 the association between HMOs and late-onset neonatal sepsis.

272 sues, and reduced body weight and death from neonatal sepsis.

273 hey are a potential protective agent against neonatal sepsis.

274 The comparison with neonatal single-nucleus sequencing data showed a differe

275 tween 39 and 47 weeks postmenstrual age on a neonatal-sized, neonatal ICU-sited 1.5-T magnetic resona

276 rm to leverage the regenerative abilities of neonatal skin to develop clinically tractable solutions

277 and then re-trained this prototype using 291 neonatal subjects without supervision.

278 inutes provided prognostic information about neonatal survival among preterm infants across gestation

279 will highlight new evidence indicating that neonatal T cells are not inert or less potent versions o

280 Using a mouse model of neonatal tendon regeneration, we identified TGFbeta sign

281 ing as a major molecular pathway that drives neonatal tendon regeneration.

282 These results demonstrate that neonatal Tgammadelta17 cells are innate skin regulatory

283 Amniotic fluid, cord blood, neonatal throat swab, and breastmilk samples from six pa

284 Neonatal tissue damage induces long-term deficits in inh

285 port switching of fibroblast subtypes from a neonatal to adult state and this drives cardiomyocyte ma

286 pe was purely myopathic, ranging from lethal neonatal to mild ambulatory adult patients.

287 Consistent with improved neonatal tolerance, the offspring of mothers with T1D ha

288 Neonatal treatment with the ER stress-relieving drug tau

289 At birth, neonatal triceps and subscapular skinfold thicknesses we

290 ojections, all of which are ameliorated with neonatal TUDCA treatment.

291 ernal peripheral blood mononuclear cells and neonatal umbilical cord blood mononuclear cells were col

292 station), preterm and cesarean delivery, and neonatal unit admission in the months preceding vs durin

293 l disparity between prepartum maturation and neonatal upregulation of mitochondrial oxidative capacit

294 4, and Sox17, as well as genes important for neonatal uterine differentiation (Wnt7a, Hoxa10, and Msx

295 ress at birth, need for supplemental oxygen, neonatal ventilator use, and neonatal resection (p < 0.0

296 id hormones, with potential consequences for neonatal viability and adult metabolic health.

297 In addition, we found that neonatal vitamin D status was not predictive of the subs

298 ental animals are intrinsically sensitive to neonatal vocalizations, or instead learn about vocal cue

299 t OPC-endothelial cell interactions regulate neonatal white matter vascular development in a Wnt-depe

300 than 19 years old at discharge and were not neonatal with a discharge diagnosis of sepsis.