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1 ntained within the cytoplasmic domain of the neonatal Fc receptor.
2 t on binding to human FcgammaRI, C1q, or the neonatal Fc receptor.
3 /H435Q) with minimal affinity for the murine neonatal Fc receptor.
4 vent capsid spike interaction with the human neonatal Fc receptor.
5 gagement with its cognate cellular recycling neonatal Fc receptor.
6 cations of an increase in IgG binding to the neonatal Fc receptor.
7 ion complexes, which are transcytosed by the neonatal Fc receptor across syncytiotrophoblasts, infect
8 red to increase affinity at acidic pH to the neonatal Fc receptor, and to reduce effector functions.
9 a gravis (gMG) treated with efgartigimod, an neonatal Fc receptor antagonist, under the Early Access
11 nt deposition, opsonophagocytic killing, and neonatal Fc receptor binding while tested against capsul
13 erefore, we aimed to evaluate nipocalimab, a neonatal Fc receptor blocker that reduces circulating Ig
16 lly, improvements directed at binding to the neonatal Fc receptor can endow therapeutic antibodies wi
17 rint has some overlap with that seen for the neonatal Fc receptor complexed with enterovirus E6 but i
18 alent in endothelial cells, macrophages, and neonatal Fc receptor-expressing cells in the placental t
19 natriuretic peptide receptor A IgG4 with the neonatal Fc receptor, Fcgamma receptors, and complement-
24 knockout and activation screens to identify neonatal Fc receptor (FcRn) and dipeptidyl-peptidase IV
25 iometry of immunoglobulin G (IgG) binding to neonatal Fc receptor (FcRn) and Fcgamma receptor (Fcgamm
26 th diverse types of receptors, including the neonatal Fc receptor (FcRn) and Fcgamma receptors (Fcgam
27 ibody fragments lack the ability to bind the neonatal Fc receptor (FcRn) and have reduced half-lives.
28 blood by transcytosis across the BBB via the neonatal Fc receptor (FcRn) and the low-density lipoprot
31 (Fv) of IgG antibodies on the binding to the neonatal Fc receptor (FcRn) as well as on FcRn-dependent
32 A) and IgG, through its Fc part, bind to the neonatal Fc receptor (FcRn) at low pH in the endosome af
33 erved Fc methionine residues and the loss of neonatal Fc receptor (FcRn) binding and complement-depen
34 Functional studies by antigen binding and neonatal Fc receptor (FcRn) binding correlated very well
35 igimod), an engineered IgG1 Fc with enhanced neonatal Fc receptor (FcRn) binding, which reduced total
37 ort the three-dimensional structure of human neonatal Fc receptor (FcRn) bound concurrently to its tw
42 me MHC class I-related molecules such as the neonatal Fc receptor (FcRn) execute their function witho
43 ansferred across the placenta by binding the neonatal Fc receptor (FcRn) expressed within the endosom
49 (monoFc) maintained the binding affinity for neonatal Fc receptor (FcRn) in a pH-dependent manner.
50 ellular traffic of IgG mediated by the human neonatal Fc receptor (FcRn) in fibroblast cell lines wit
51 tudy the involvement of immune complexes and neonatal Fc receptor (FcRn) in the emergence of ADAs in
57 nd in vivo analyses, the MHC class I-related neonatal Fc receptor (FcRn) is known to play a central r
61 ects proteins for lysosomal degradation, the neonatal Fc receptor (FcRn) located at the brush border
66 (PPI-Fc) is delivered to fetuses through the neonatal Fc receptor (FcRn) pathway, which physiological
71 -dependent affinity of IgG molecules for the neonatal Fc receptor (FcRn) receptor primarily arises fr
73 ed endothelial cell (EC) injury, loss of the neonatal Fc receptor (FcRn) responsible for IgG recyclin
74 Serum half-life of IgG is controlled by the neonatal Fc receptor (FcRn) that interacts with the IgG
76 t in blood, syncytiotrophoblasts express the neonatal Fc receptor (FcRn) that transports IgG for pass
84 gG1 IC and formed a ternary complex with the neonatal Fc receptor (FcRn) under acidic conditions.
85 bodies via pharmacological inhibition of the neonatal Fc receptor (FcRn) using high-dose IgG therapy.
87 c fragment of immunoglobulin G (IgG) and the neonatal Fc receptor (FcRn) was determined at low resolu
90 eered to enhance interactions with the human neonatal Fc receptor (FcRn) without loss of the oligomer
91 ologic inhibition or genetic deletion of the neonatal Fc receptor (FcRn) would attenuate mechanical h
92 ng site on Fcgamma overlaps with that of the neonatal Fc receptor (FcRn), an interaction that is crit
93 regulated the constitutive expression of the neonatal Fc receptor (FcRn), an MHC class I-related mole
94 crossed the placenta, dependent on the fetal neonatal Fc receptor (FcRN), and sensitized fetal MCs fo
95 by the cells, the binding affinity of mAb to neonatal Fc receptor (FcRn), and the intracellular degra
96 pH-dependent interaction between IgG and the neonatal Fc receptor (FcRn), as FcRn is the main homeost
97 expression of the relevant receptor, namely neonatal Fc receptor (FcRn), by Calu-3 cell layers simul
99 logue of the primary echovirus receptor, the neonatal Fc receptor (FcRn), is not sufficient for infec
101 s, facilitated by interaction with the human neonatal Fc receptor (FcRn), that promotes it as a highl
104 gG is transported across the placenta by the neonatal Fc receptor (FcRn), which recognizes the Fc dom
106 gGs is ensured by their interaction with the neonatal Fc receptor (FcRn), which salvages IgG from int
107 tibodies at these sites is influenced by the neonatal Fc receptor (FcRn), whose role in protecting ag
108 conjugate (rHA-CpG) designed to exploit the neonatal Fc receptor (FcRn)-driven albumin cellular sort
110 offspring by instructing T reg formation via neonatal Fc receptor (FcRn)-mediated transfer and uptake
121 heir ability to interact with the protective neonatal Fc receptor (FcRn, Brambell receptor) present o
122 on half-life, pharmacokinetics defining the neonatal Fc receptors (FcRn) and most important safety o
124 udy was to determine the contribution of the neonatal Fc-receptor (FcRn) in rat brain efflux employin
127 r histocompatibility complex class I-related neonatal Fc receptor, FcRn, assembles as a heterodimer c
138 ocyte-derived CD8(-)CD11b(+) DCs require the neonatal Fc receptor for IgG (FcRn) to conduct cross-pre
140 Darby canine kidney cells expressing the rat neonatal Fc receptor for IgG (FcRn), it significantly re
147 findings support the mechanism of action of neonatal Fc receptor inhibition in generalised myastheni
148 imab are clinically approved for PV, but the neonatal Fc receptor inhibitor efgartigimod and Bruton's
152 I but also the related CD1a, CD1b, CD1c, and neonatal Fc receptor molecules were absent from the surf
155 y CD1), transport of immunoglobulins (by the neonatal Fc receptor), regulation of iron metabolism (by
158 mediates transcytosis through binding to the neonatal Fc receptor, the peptidomimetic introduces cros
160 we show that this effect is dependent on the neonatal Fc receptor, which rescues the dissociated anti
161 lass novel human IgG1 Fc fragment, binds the neonatal Fc receptor with high affinity and thus reduces