ライフサイエンスコーパス: neonatally

1 develop in homozygotes and these animals die neonatally.

2 AKR and NFS strains when they are inoculated neonatally.

3 nated axons that impeded motor axon function neonatally.

4 hat express the receptor tyrosine kinase Ret neonatally.

5 te loss of paternal gene expression and died neonatally.

6 -) pups develop severe hydrocephalus and die neonatally.

7 lapsing neuropathology in the adult brain of neonatally AAV-gene therapy-treated Twitcher mice identi

8 creased expression of MBP, SOX10 and MYRF in neonatally Abx-treated mice compared to sham controls in

9 roup included all seven patients with a post-neonatally acquired or progressive brain lesion who coul

10 normal preoperative hand function and a post-neonatally acquired or progressive lesion predict a loss

11 e functional organization of this nucleus in neonatally amputated adult rats.

12 At the brainstem level, neonatally amputated rat cuneate neurons possessed the f

13 ignificantly smaller (P < 0.05) than that of neonatally amputated rats (4.3 +/- 1.3 mm(2) vs. 6.6 +/-

14 e to peripheral stimulation vs. neurons from neonatally amputated rats (48% vs. 16%, respectively).

15 functional reorganization observed in SI of neonatally amputated rats may reflect functional alterat

16 associated with the stump and hindlimb SI in neonatally amputated rats.

17 we show that mutant mice lacking miR-218 die neonatally and exhibit neuromuscular junction defects, m

18 sgenic lines were homozygote inviable, dying neonatally and exhibiting heart malformations involving

19 hat many human atopic diseases are initiated neonatally and herald more severe IgE-mediated disorders

20 ons is located exclusively in dendrites both neonatally and in adulthood.

21 were more robust in animals exposed to acid neonatally and rechallenged, acutely, at P60.

22 As adults, neonatally antisense-treated, androgenized females showe

23 lumbar levels does not enhance the growth of neonatally axotomized DC axons.

24 After rechallenge of adult rats, neonatally B-chain-tolerized animals showed diminished B

25 the mechanisms of activation of microglia in neonatally BDV-infected rat brain have not been investig

26 thick skin and a defective barrier; they die neonatally because of dehydration and restricted movemen

27 ring adulthood since the deletion of Rnd2 in neonatally-born granule neurons only affects dendritogen

28 Given neonatally, BPZE1 also protected against RSV-induced wei

29 ter weaning was less effective than treating neonatally but still extended the lifespan of CLN1 disea

30 Homozygous Orai1(KI/KI) mice die neonatally, but Orai1(KI/KI) fetal liver chimeric mice a

31 (-)2(-)7(+) and CD3(-)2(+)7(+), were present neonatally, but were essentially absent at 1 year.

32 the hindlimb of normal, cardiomyopathic and neonatally capsaicin-treated (NNCAP) rats (rats that lac

33 nduced PR protein and mRNA in the female and neonatally castrated male MPN on PN 4, indicating that t

34 tosis in the developing MPNc was examined in neonatally castrated males following T or vehicle inject

35 Subsequently, we found that treating neonatally castrated males with testosterone propionate

36 arlier rise in CBT during the light phase in neonatally castrated males.

37 Thus, adult male rats neonatally castrated on the first day after birth displa

38 ver, mice with CHD invariably die prenatally/neonatally, causing CHD phenotypes to be missed.

39 arly lineage T cell populations were present neonatally: CD3(+)4(-)8(-) T cells were present at birth

40 into the striata of adult mice that had been neonatally chimerized with mutant Huntingtin (mHTT)-expr

41 se-2 (MKP-2) during adulthood in control and neonatally CLI-treated rats (CLI rats).

42 munocompetent cells in the brain, are active neonatally, contribute to normal brain development, and

43 ed a pronounced decrease in cell diameter in neonatally deafened cats studied about 1 year after deaf

44 tal day 0 (P0) to P90 in control hearing and neonatally deafened rats.

45 adation impairing the longitudinal growth of neonatally denervated muscles.

46 When the neonatally deprived D2 and D3 whiskers were paired at ma

47 Our findings show that most neonatally-derived hair cells become Type II, and many T

48 planted into the cheek pouches of control or neonatally DES-exposed adult hosts, and both host groups

49 ost exclusively to the two that consisted of neonatally DES-exposed uteri.

50 tion was maintained in uterine tumors of the neonatally DES-treated mice.

51 is site, however, remained methylated in the neonatally DES-treated/ovariectomized mice, indicating t

52 Mice with FLVCR that is deleted neonatally develop a severe macrocytic anemia with proer

53 n the efficacy of prenatally transferred and neonatally developed viral immunity has yet to be addres

54 In mice, neonatally-developing, self-reactive B-1 cells generate

55 in the gene of its ligand (endothelin 1) die neonatally due to craniofacial and cardiac abnormalities

56 skin and a defective skin barrier; they die neonatally due to dehydration and restricted movements.

57 and a defective epidermal barrier; they die neonatally due to dehydration and restricted movements.

58 ronal and muscle ion channels, but can occur neonatally due to placental transfer of maternal antibod

59 Neonatally engrafted hiPSC OPCs robustly myelinated the

60 D, we established human HD glial chimeras by neonatally engrafting immunodeficient mice with mutant h

61 anomalous, mirror-symmetric map observed in neonatally enucleated animals, are present by P6-7, just

62 ysis of susceptibility to viral infection in neonatally exposed mice revealed that CD28 deficiency di

63 tributes to the adult sexual deficit in rats neonatally exposed to citalopram.

64 However, offspring neonatally exposed to cocaine displayed a greater drug-i

65 In a 3-hr preference test, males neonatally exposed to exogenous OT exhibited a significa

66 not arise at increased frequency in animals neonatally exposed to ionizing radiation or the carcinog

67 l dose of the barbiturate, males and females neonatally exposed to phenobarbital exhibited a dramatic

68 aine was more pronounced in female offspring neonatally exposed to the drug.

69 sor exhibit two distinct clinical phenotypes-neonatally fatal and later-onset.

70 ransgene of an NMDAR1 splice variant rescues neonatally fatal NMDAR1 knockout (KO) mice, although the

71 In contrast, Fatp4(-/-) mice die neonatally from a defective barrier.

72 Connexin43 knockout mice die neonatally from conotruncal heart malformation and outfl

73 males that were exposed to 160 microg/ml CSC neonatally had increased rates of pup resorption.

74 Adult male mice neonatally handled for 10 min/day exhibited a blunted co

75 Thus, neonatally implanted hGPCs outcompeted and ultimately re

76 Kittens were deafened neonatally, implanted at 4-5 weeks with intracochlear el

77 of Abeta- and Adelta-fiber input observed in neonatally-incised mice compared with naive littermate c

78 Neonatally induced microgyric lesions produce defects in

79 Thus, recovery from neonatally induced T cell anergy requires B7 molecules t

80 LPS challenge prevents memory impairment in neonatally infected (NI) rats.

81 in vulnerability were replicated in vivo in neonatally infected LEW and SD rats.

82 but, like the parent virus, it persisted in neonatally infected mice without clinical signs of disea

83 Furthermore, quinolinic acid was elevated in neonatally infected rat brains.

84 KMO protein levels were increased in neonatally infected rats and colocalized with neurons, t

85 After LPS, neonatally infected rats exhibited faster increases in i

86 in glial cell marker mRNA in hippocampus of neonatally infected rats, and this increase remained ele

87 y prevented LPS-induced memory impairment in neonatally infected rats.

88 a brain region- and time-dependent manner in neonatally infected rats; however, its expression was hi

89 y onto CA1 pyramidal neurons from control or neonatally inflamed adolescent mice of either sex.

90 s acute cerebral amyloid angiopathy (CAA) in neonatally-injected transgenic CRND8 mice.

91 ltured MSCs can restore normal compliance in neonatally injured lungs, possibly by paracrine modulati

92 duces clinical neurologic disease in 100% of neonatally inoculated mice, with an incubation period of

93 NIH/Swiss mice neonatally inoculated with MoFe2 developed T-cell lympho

94 ed from the spleen of a Mus spicilegus mouse neonatally inoculated with Moloney MLV.

95 Neonatally irradiated and control Ptch1(+/-) mice were c

96 th factor beta/Smad signaling pathway in the neonatally irradiated lens, and up-regulation of mesench

97 arlier in life in ARF-null animals that were neonatally irradiated or given dimethylbenzanthrene, and

98 g was measured in several brain regions from neonatally isolated (ISO) and nonhandled (NH) adult male

99 on (LTD) of BLA-DG synapses were recorded in neonatally isolated and non-handled freely behaving adul

100 Atelosteogenesis type II (AO II) is a neonatally lethal chondrodysplasia whose clinical and hi

101 ment of pulmonary veins (ACD/MPV) is a rare, neonatally lethal developmental disorder of the lung wit

102 s of human skeletal dysplasia, including the neonatally lethal dwarfism known as thanatophoric dyspla

103 inactivation of individual ENaC subunits is neonatally lethal in mice.

104 ndrome (MKS) is a genetically heterogeneous, neonatally lethal malformation and the most common form

105 nclude the most severe forms of MFS, such as neonatally lethal presentations.

106 des of FATP4 expression led to rescue of the neonatally lethal skin defects, and the resulting mice w

107 In mice, the complete lack of CBS is neonatally lethal.

108 nction affects all expressing tissues and is neonatally lethal; heterozygous null mutations cause ani

109 Neonatally, males received either an injection of OT, an

110 Recordings from VPL of neonatally manipulated rats revealed a small, but signif

111 y neurotransmitters, and as Gad1-/- mice die neonatally of severe cleft palate, it has not been possi

112 etrograde tracers into the MGN of normal and neonatally operated adult ferrets, respectively.

113 it cognitive changes in trisomic mice either neonatally or in adulthood.

114 n d3tx female mice, d3tx male mice, and d3tx neonatally ovariectomized (OX) females.

115 pare this to the development in rats treated neonatally (postnatal days 2-14) with anti-NGF.

116 A combination of 4 factors available neonatally predicted 78% of severe and 49% of attenuated

117 However, Prdm16 germline knockout mice died neonatally, preventing us from testing whether Prdm16 is

118 The enhanced neuroimmune response seen in neonatally primed animals could also be demonstrated in

119 amines were examined in adult rats which had neonatally received bilateral intracerebroventricular in

120 long lasting; rats trained at PND 60, after neonatally receiving the original high dose of MK-801, d

121 s administered 6-OHDA soon after weaning, or neonatally, respectively model Parkinson's disease (PD)

122 We hypothesized that increased GABA neonatally results in masculinization.

123 Neonatally screened carriers also had neuroblastoma (n =

124 osed in 11 of these carriers but in only two neonatally screened noncarriers (P < .001); six patient

125 mice undergoing primary infection as adults, neonatally sensitized mice showed enhanced airway fluid

126 Lungs of neonatally sensitized mice showed increased 5-lipoxygena

127 of orexin and orexin receptors in adult rats neonatally subjected to either ten days of MD or a contr

128 isogenic WT cells that had been transplanted neonatally, suggesting that competitive success depended

129 hat the development of autoimmune disease in neonatally thymectomized mice is caused by the escape of

130 in which retinal projections are redirected neonatally to the auditory thalamus have visually respon

131 Female mice exposed neonatally to the phytoestrogen genistein (GEN) at doses

132 ly reported that prolonged graft survival in neonatally tolerant mice was associated with enhanced Th

133 Similarly, LEW rats neonatally tolerized against either Rhsp65 or Bhsp65 wer

134 Neonatally tolerized animals were unable to mount antibo

135 nsgenic mouse model in which CD8 T cells are neonatally tolerized following interaction with a parenc

136 ing induction of EAE in adult mice that were neonatally tolerized with Ig-PLP1 restores and exacerbat

137 Neonatally transplanted human glial progenitor cells (hG

138 ly in adult transplanted mice but not in the neonatally transplanted mice.

139 , the adult splenic T cell response of these neonatally treated mice lacked the usual Vbeta8.2Jbeta1.

140 ides safe and durable therapeutic benefit in neonatally treated MMA mice.

141 Animals neonatally treated with kainate, (+/-)-1-amino-1,3-cyclo

142 o sham-operated males, and adult female rats neonatally treated with testosterone propionate on the f

143 Neonatally undernourished females display attenuated pos

144 Neonatally vaccinated infants, infants born to vaccinate

145 s neutralizing Ab titers sufficed to protect neonatally vaccinated mice against a subsequent challeng

146 ralizing antibody titers sufficed to protect neonatally vaccinated mice against a subsequent challeng

147 DGCs generated neonatally were compared with those generated in adultho

148 MHC-II(-) MM were abundant neonatally, whereas MHC-II(+) MM appeared over time.

149 We find that Atf5(-/-) pups die neonatally, which, as explained below, is consistent wit

150 in a transfer system, whereas those treated neonatally with anti-TNF show no alteration in ability t

151 Animals treated neonatally with capsaicin, to eliminate C-fiber input, d

152 and mature (21- and 30-day-old) mice treated neonatally with DES.

153 Adult rats treated neonatally with E. coli also had decreased hippocampal a

154 In experiment 2, rats treated neonatally with E. coli or PBS received as adults either

155 Next, rats treated neonatally with E. coli or PBS were injected in adulthoo

156 morphine analgesia than female rats treated neonatally with either vehicle (1-5 mg/kg) or testostero

157 rian hamsters retain-->of both sexes treated neonatally with monosodium glutamate (MSG) that destroys

158 Females treated neonatally with NBQX (2,3-dihydroxy-6-nitro-7-sulfonyl-b

159 ons die in utero with a phenocopy of DGS, or neonatally with neural tube defects.

160 ntile-onset Pompe disease (IOPD), presenting neonatally with severe hypertrophic cardiomyopathy, prof

161 In rats infected neonatally with the Borna disease virus that lack blood-

162 Surprisingly, mice treated neonatally with these antibiotics develop exacerbated ps

163 iii) CD4+CD25+ T cells from NOD mice treated neonatally with TNF show compromised effector function i

164 In adulthood, rats infused neonatally with TTX displayed motor hyperactivity after

165 nged the potency (20-30%) in females treated neonatally with vehicle.