ライフサイエンスコーパス: nerve conduction

1 roduction with the increased energy needs of nerve conduction.

2 ical illness and early recovery and assessed nerve conduction.

3 L-NNA abolished C-peptide effects on nerve conduction.

4 al phenotype with only a slight reduction in nerve conduction.

5 entifying the effects of these antibodies on nerve conduction.

6 ubjects and 11 diabetic patients with normal nerve conduction.

7 (4-AP) nor tetraethylammonium alters normal nerve conduction.

8 the sheath as an insulating layer for proper nerve conduction.

9 rain, muscle, immune, metabolism, mucoid and nerve conduction.

10 oligodendrocytes is essential for saltatory nerve conduction.

11 xhibit neurological abnormalities and slower nerve conduction.

12 approach to identify novel genes controlling nerve conduction.

13 rength, proprioception, tendon reflexes, and nerve conductions.

14 ssive peripheral neuropathy characterized by nerve conduction abnormalities as well as extensive musc

15 after transplantation, a composite score of nerve conduction abnormalities, an independent measure o

16 endent sodium channel antagonist that blocks nerve conduction, abolished both the oxidation current a

17 lar decompression leads to rapid recovery of nerve conduction across the indented root, a phenomenon

18 kinase, muscle strength and function, motor nerve conduction, activities of daily living, and erecti

19 s an axonal insulator that facilitates rapid nerve conduction along axons.

20 They appear to be involved in nerve conduction and cell adhesion, but their precise ph

21 e-deficient (Cgt(-/-)) mice exhibit aberrant nerve conduction and display virtually no HSPC egress fr

22 tion, as well as electrophysiologic studies (nerve conduction and electrochemical skin conductance) a

23 ropathy as indicated by changes in behavior, nerve conduction and histology.

24 ne as this dose only prevented the change in nerve conduction and hot-plate latencies.

25 of function of these channels at NRs retards nerve conduction and impairs sensory behavioral response

26 Two patients had temporal dispersion of nerve conduction and irregularity of conduction slowing,

27 hancing myelin regeneration, hence restoring nerve conduction and metabolic support to the axon.

28 rements in motor/sensory neuron myelination, nerve conduction and muscle function; however, the mecha

29 d time-dependently prevented the deficits in nerve conduction and nerve blood flow and biochemical ab

30 axons, as well as the functions of myelin in nerve conduction and neural circuits, and consider its p

31 ibition, prevented demyelination, leading to nerve conduction and neuromuscular performance recovery

32 Moreover, although deficits in nerve conduction and neuromuscular transmission were obs

33 the brain, myelin is important in regulating nerve conduction and neurotransmitter release by providi

34 Schwann cell dystroglycan results in slowed nerve conduction and nodal changes including reduced sod

35 orming oligodendrocytes facilitate saltatory nerve conduction and support neuronal functions in the m

36 n is essential for the rapidity of saltatory nerve conduction, and also provides trophic support for

37 xamination scores, visual analog pain scale, nerve conduction, and quantitative sensory testing.

38 cipants underwent standardized examinations, nerve conduction, and skin biopsy at 3 sites along the l

39 pinal motor axons, causing pain, inefficient nerve conduction, and the ectopic migration of oligodend

40 central autonomic regulation and sympathetic nerve conduction, and the norepinephrine transporter (NE

41 integrity of the myelin sheath and defective nerve conduction as indicated by morphological and elect

42 ec), and FF (b = -4.0%) were associated with nerve conduction at calf level (P < .001).ConclusionMRI

43 cal muscles, following recovery from chronic nerve conduction block.

44 oss of ion channel segregation, and impaired nerve conduction, but the mechanisms regulating their in

45 because they increase the speed of saltatory nerve conduction, but they also represent potential bott

46 se they increase the efficiency of saltatory nerve conduction, but they also represent potential bott

47 s and respond to stress or injury, and rapid nerve conduction can provide instantaneous input for mod

48 Peripheral motor and sensory nerve conduction, central motor conduction, a clinical n

49 eks of CNTF treatment significantly improved nerve conduction compared with untreated diabetic rats a

50 ts were classified into five groups by motor nerve conduction criteria; 69% were demyelinating, 3% ax

51 indices of abnormality of motor and sensory nerve conduction decreased significantly at all interval

52 ly corrected thermal hypoalgesia and sensory nerve conduction deficit without affecting motor nerve c

53 sciatic motor and hind-limb digital sensory nerve conduction deficits and sciatic nerve energy state

54 hermore, electrophysiological studies reveal nerve conduction deficits in the spinal cord of these mu

55 They also had motor and sensory nerve conduction deficits, tactile allodynia, and therma

56 resulted in significant normalization of the nerve conduction deficits.

57 schemia and axonal dwindling in the reported nerve conduction deficits.

58 Optic nerve conduction delays depend on RGC axon conduction ve

59 early ensheathing Schwann cells, and altered nerve conduction during development.

60 rupts paranodal junction assembly and delays nerve conduction during early development in mice.

61 otoxic effects of vincristine as measured by nerve conduction, gait, response to noxious stimuli and

62 assessments of clinical features, peripheral nerve conduction, H and F components, threshold tracking

63 showed normal large fibre sensory and motor nerve conduction; however, skin biopsy showed a signific

64 Thus, slower peripheral nerve conduction in carpal tunnel syndrome corresponds t

65 Rapid nerve conduction in myelinated nerves requires the clust

66 s may be linked to demyelination and reduced nerve conduction in peripheral neuropathies.

67 ds mature myelin sheaths, facilitating rapid nerve conduction in the healthy CNS.

68 fully correlate with the presence of delayed nerve conduction in the median nerve.

69 s and adhesion molecules essential for rapid nerve conduction in vertebrates are differentially targe

70 models displayed a significant decrement in nerve conduction, increase in tail distal motor latency

71 results in accelerated recovery of saltatory nerve conduction, increased innervation as detected by n

72 The motor and sensory nerve conduction indices increased significantly at all

73 Impairment of nerve conduction is common in neurodegenerative and neur

74 Upon demyelination, saltatory nerve conduction is disrupted, and patients experience n

75 Huxley's seminal discovery that the crux of nerve conduction is ion flow across cellular membranes.

76 neurological and reproductive deficits: CNS nerve conduction is slowed, hindlimb weakness is conspic

77 eeks, measured as recovery of affected optic nerve conduction latency using full-field visual evoked

78 both local to the wrist (i.e. median sensory nerve conduction latency) and in the brain (i.e. digit 2

79 The abnormality of attributes of nerve conduction may be used to validate the dysfunction

80 ociated with severe paroxysmal pain in which nerve conduction may have a key role.

81 blood flow (NBF) vs. other factors in motor nerve conduction (MNC) slowing in short-term diabetes wa

82 By promoting rapid, efficient nerve conduction, myelination also made possible the dev

83 In addition to increasing the speed of nerve conduction, myelination has emerged as a source of

84 mechanism by which PMP22 deficiency affects nerve conduction not through removal of myelin, but thro

85 ith the blood chemistry panel and peripheral nerve conduction of Chinese farmers.

86 In all, 155 were tested for nerve conduction of sensory and motor median nerve laten

87 ptoms had only a 40% sensitivity for delayed nerve conduction on latency testing.

88 ly sites where APs can be regenerated during nerve conduction on myelinated nerves, ion channel mecha

89 Scrambled C-peptide was without effect on nerve conduction or perfusion.

90 B-12, holotranscobalamin, or cB-12 with any nerve conduction outcome.

91 ed no significant deleterious effects on any nerve conduction parameter measured and caused milder, l

92 on was used to investigate associations with nerve conduction parameters in participants without poly

93 Improvements in peripheral nerve conduction positively correlated with cytokine-ind

94 Other measures including nerve conduction potentials did not improve.

95 ellular location of Caspr was disrupted, and nerve conduction properties remained immature.

96 eurological examination and abnormalities of nerve conduction, quantitative sensory tests, and quanti

97 Patterns of hand symptoms were compared with nerve conduction results and associations weighted back

98 s of capacitance and serious disturbances in nerve conduction, severely damaging brain function.

99 etic and galactose-induced motor and sensory nerve conduction slowing and nerve energy failure that w

100 s have an increased risk for developing both nerve conduction slowing and small sensory fiber neuropa

101 limb digital sensory, but not sciatic motor, nerve conduction slowing and thermal and mechanical hypo

102 aused peripheral neuropathy, as indicated by nerve conduction slowing and thermal hyperalgesia.

103 et of 8 weeks of galactose feeding prevented nerve conduction slowing in a dose-dependent manner.

104 ry nerve terminals, thermal hypoalgesia, and nerve conduction slowing in diverse rodent models of dia

105 e conduction deficit without affecting motor nerve conduction slowing.

106 To meet the energy demands of nerve conduction, small mitochondria are transported to

107 used for association between MRI parameters, nerve conduction, strength, and body mass index (BMI).Re

108 A subset of patients underwent nerve conduction studies (n = 13).

109 Nerve conduction studies (NCS) may be used at the subcli

110 mination, needle electromyography (EMG), and nerve conduction studies (NCS) were performed before and

111 ertaken in 108 type 2 diabetic patients with nerve conduction studies (NCS), HbA(1c) levels, and tota

112 Neurophysiological measures included nerve conduction studies (NCS), quantitative sensory tes

113 cal clinical presentations, demyelination on nerve conduction studies (p = 0.0005), and difficult ide

114 f peripheral nerve lesions routinely involve nerve conduction studies and electromyography.

115 tibialis anterior muscle was confirmed with nerve conduction studies and immunohistochemical analysi

116 and a global symptom assessment, as well as nerve conduction studies and occurrence of new plantar f

117 l examination, quantitative sensory testing, nerve conduction studies and skin biopsy for intraepider

118 exopathy was made after electromyography and nerve conduction studies and the etiology of radiculopat

119 Nerve conduction studies are considered essential for a

120 a lesion site precisely, where fractionated nerve conduction studies are not applicable.

121 ited, however, by problems inherent in using nerve conduction studies as a criterion standard.

122 Nerve conduction studies assessing median nerve sensory

123 l syndrome should be investigated first with nerve conduction studies but consideration should be giv

124 rical irritability; 13 patients had abnormal nerve conduction studies but four of these had long-stan

125 s of peripheral nerve cannot proceed without nerve conduction studies but particular interest has bee

126 is also disagreement about whether pudendal nerve conduction studies can be used to predict outcome

127 ropsychological testing remained stable, and nerve conduction studies have shown improvement.

128 arge fiber sensory polyneuropathy on sensory nerve conduction studies in all patients associated with

129 ralysis in 10 percent; in all of the latter, nerve conduction studies indicated an axonal polyneuropa

130 Nerve conduction studies localised abnormalities to the

131 Nerve conduction studies revealed no evidence of neuropa

132 Electromyography/nerve conduction studies showed evidence for a mild myop

133 Nerve conduction studies showed normal large fibre senso

134 Serial nerve conduction studies showed progressively reduced am

135 Nerve conduction studies showed severe axonal sensorimot

136 ropathy caused by an H10P MPZ mutation whose nerve conduction studies suggested severe axonal loss bu

137 s], we used quantitative sensory testing and nerve conduction studies to evaluate the function of lar

138 Nerve conduction studies were also performed, and neurop

139 Nerve conduction studies were normal, but increased jitt

140 In all cases, large fibre nerve conduction studies were normal.

141 Results of nerve conduction studies were retrieved and assessed.

142 Blood examination and nerve conduction studies were unremarkable.

143 urological function by clinical examination, nerve conduction studies, and autonomic function tests i

144 ons in patients with suspected neuropathies, nerve conduction studies, and magnetic resonance imaging

145 n, functional and walking disability scores, nerve conduction studies, and muscle biopsies are report

146 Physical examinations, questionnaires, nerve conduction studies, and NFTs, including the Jebsen

147 ength, tendon reflexes, vibration sense, and nerve conduction studies, and reduced intraepidermal ner

148 ile capacity and performed electromyography, nerve conduction studies, and vastus lateralis biopsies

149 Clinical examinations, nerve conduction studies, and vibratory perception thres

150 Nerve conduction studies, needle electromyography, singl

151 Neuroimaging, nerve conduction studies, neurological examinations, and

152 rs were studied, using clinical examination, nerve conduction studies, perimetry, optical coherence t

153 version 2 (CMTNSv2), CMTNSv2-Rasch modified, nerve conduction studies, quantitative sensory testing,

154 Nerve conduction studies, quantitative sensory testing,

155 y skin biopsy, quantitative sensory testing, nerve conduction studies, screening of genomic DNA for m

156 h measurements may be comparable to those of nerve conduction studies, though their prognostic value

157 s precede functional anomalies detectable on nerve conduction studies.

158 erties and are complementary to conventional nerve conduction studies.

159 commonly than motor axonal polyneuropathy on nerve conduction studies.

160 questionnaire, neurological examination and nerve conduction studies.

161 sts for the evaluation of the motor unit are nerve conduction studies/electromyography (NCS/EMG) and

162 Toxicity assessment included nerve-conduction studies (NCS) and radionuclide assessme

163 Among 46 patients in whom nerve-conduction studies and electromyography were perfo

164 Nerve conduction study (NCS) abnormalities suggestive of

165 The nerve conduction study (NCS) and electromyography (EMG)

166 DPN was defined by symptoms, signs, and nerve conduction study abnormalities in >=2 nerves; CAN

167 cale scores, greater reduction of upper limb nerve conduction study amplitudes, more frequent occurre

168 forms (7.7% vs. 5.3%; p=0.63) with a single nerve conduction study as compared with when serial elec

169 luded intraepidermal nerve fiber density and nerve conduction study parameters.

170 smission at neuromuscular junctions, whereas nerve conduction, synaptic structure, and spontaneous sy

171 questionnaire on current hand symptoms, and nerve conduction testing in samples of subjects with and

172 e neuropathy score version 1 or 2 and slower nerve conductions than the other groups, and severity in

173 Digital nerve conduction underwent a dose-dependent improvement

174 Nerve conduction, vascular and airway dynamics, and prop

175 f memory, attention, visuomotor function, or nerve conduction velocities (average z scores were very

176 voluntary locomotor activity, reduced motor nerve conduction velocities (MNCVs) and muscle atrophy.

177 uced diabetic rats with decreased peripheral nerve conduction velocities (NCV).

178 Negative correlations were found with sural nerve conduction velocities (NCVs) (r = -0.65, P < 0.001

179 and FA values were correlated to electrical nerve conduction velocities (NCVs) with Pearson correlat

180 Patients with CMT1A typically have slowed nerve conduction velocities (NCVs), reduced compound mot

181 Sural nerve myelinated fiber density (MFD), nerve conduction velocities (NCVs), vibration perception

182 a markedly low birth weight, very slow motor nerve conduction velocities and a general decrease in th

183 muscle action potential amplitudes, improved nerve conduction velocities and ameliorated muscle stren

184 thy with hypo- and demyelination, slowing of nerve conduction velocities and disturbed nodal architec

185 ice experienced significant deterioration in nerve conduction velocities and IENF density and develop

186 high-fat diet to a MUFA-rich high-fat diet; nerve conduction velocities and intraepidermal nerve fib

187 on protein fully restored motor- and sensory-nerve conduction velocities and maintained the axonal ca

188 (R98C/R98C) mice develop weakness, abnormal nerve conduction velocities and morphologically abnormal

189 g, mitochondrial DNA deletions, reduction of nerve conduction velocities and of heat sensation, and b

190 al recovery as assessed by motor and sensory nerve conduction velocities and sciatic functional index

191 Guillain-Barre syndrome, we determined that nerve conduction velocities between the sciatic notch an

192 Ulnar and median nerve conduction velocities confirmed the clinical diagn

193 Here we measured nerve conduction velocities in a rabbit model of limb le

194 yses also reveal that the reduction of motor nerve conduction velocities in affected patients is prop

195 g the formation of compact myelin and normal nerve conduction velocities in the homozygous state.

196 Motor nerve conduction velocities of the fastest fibers are se

197 ents from six pedigrees (n = 38) had reduced nerve conduction velocities ranging from 7.5 to 27.0m/se

198 Moreover, motor nerve conduction velocities were increased in treated Sh

199 orphology and impaired transmission, reduced nerve conduction velocities, and a loss of large-diamete

200 rial nutritive blood flow, motor and sensory nerve conduction velocities, and metabolic abnormalities

201 ep-tendon reflexes, sensory impairment, slow nerve conduction velocities, and nerve demyelination.

202 METHODS AND We found that motor and sensory nerve conduction velocities, blood flow, and capillary d

203 nerve fibers, specifically sural or sciatic nerve conduction velocities, but significantly improved

204 by significant slowing of motor and sensory nerve conduction velocities, compared with nondiabetic c

205 ropathy that presents in adults, with normal nerve conduction velocities, designated as a 'CMT2' form

206 rmore, treated mice showed increased sciatic nerve conduction velocities, improvement of myelination

207 Motor and sensory digital nerve conduction velocities, sciatic nerve indexes of ox

208 xtremities and displayed a mild reduction of nerve conduction velocities.

209 of onset and the degree of slowing of motor nerve conduction velocities.

210 by significant slowing of motor and sensory nerve conduction velocities.

211 e population and the horses with the slowest nerve conduction velocities.

212 rological deficit and had profoundly reduced nerve conduction velocities.

213 quadriceps muscle contractility, and sciatic nerve conduction velocities.

214 g of axons, delayed myelination, and reduced nerve conduction velocities.

215 human Schwann cells (~5%), and evaluation of nerve conduction velocity (0.13-0.28 m/sec), previously

216 vascular relaxation precede slowing of motor nerve conduction velocity (MNCV) and decreased sciatic n

217 ld) clearly developed manifest sciatic motor nerve conduction velocity (MNCV) and hind-limb digital s

218 and axonal loss, which underlie slowed motor nerve conduction velocity (MNCV) and reduced compound mu

219 Endoneurial blood flow and motor nerve conduction velocity (MNCV) were impaired in all gr

220 ic with streptozotocin, and changes in motor nerve conduction velocity (MNCV), mechanical and thermal

221 al abnormalities of EDN, i.e., reduced motor nerve conduction velocity (MNCV), total and endoneurial

222 used on either behaviors or acute changes in nerve conduction velocity (NCV) and amplitude, but great

223 They develop nerve conduction velocity (NCV) and sensory deficits pri

224 Nerve conduction velocity (NCV) significantly improved i

225 in transducing high glucose into deficits in nerve conduction velocity (NCV) that are characteristic

226 on nerve laser Doppler blood flow (NLDF) and nerve conduction velocity (NCV) were assessed after 1-16

227 heral neuropathy (DPN) is marked by impaired nerve conduction velocity (NCV), reduced nerve blood flo

228 abetes-induced deficits in sensory and motor nerve conduction velocity (P < 0.05).

229 Peroneal motor nerve conduction velocity (p=0.03) and M-wave amplitude

230 ative correlations were found for the tibial nerve conduction velocity (r = -0.23; 95% CI: -0.44, -0.

231 ative correlations were found for the tibial nerve conduction velocity (r = -0.24; 95% CI: -0.45, -0.

232 elocity (MNCV) and hind-limb digital sensory nerve conduction velocity (SNCV) deficits, thermal hypoa

233 ional attachment at the paranode and reduces nerve conduction velocity 3-fold.

234 een a ratio of 0.8 and 1.5, histological and nerve conduction velocity abnormalities are observed, bu

235 al defects, transgenic mice also have slower nerve conduction velocity and defects in their responses

236 providing critical clinical metrics such as nerve conduction velocity and histomorphometry are neces

237 ical deficits were associated with decreased nerve conduction velocity and increased sensory threshol

238 2 was positively correlated with decreasing nerve conduction velocity and increasing pain severity.

239 arkably ameliorated DPN by improving sciatic nerve conduction velocity and increasing thermal and mec

240 ripheral neuropathy characterized by reduced nerve conduction velocity and myelin outfoldings and inf

241 abetic nerve associated with improvements of nerve conduction velocity and pathologic changes.

242 Nerve conduction velocity and psychophysical data were a

243 s of large-diameter myelinated axons, slowed nerve conduction velocity and reduced amplitude of compo

244 s accompanied by decreased motor and sensory nerve conduction velocity and reduced compound muscle ac

245 th significant lowering of motor and sensory nerve conduction velocity but no alteration in the mean

246 People with severe PAD have poorer peroneal nerve conduction velocity compared with people with mild

247 it normalizes polyols and reduces the motor nerve conduction velocity deficit by 59% relative to dia

248 lgesia, tactile allodynia, motor and sensory nerve conduction velocity deficits, and reduction in tib

249 KEY POINTS: Changes in nerve conduction velocity following an impulse (i.e. vel

250 ytostatic agents and a moderate reduction of nerve conduction velocity for cisplatin and paclitaxel.

251 syndrome, but not healthy controls, sensory nerve conduction velocity for Digits 2 and 3 was slower

252 Composite motor nerve conduction velocity for the median, ulnar, and per

253 to evaluate NINM effects on pain rating and nerve conduction velocity in DPN patients.

254 e associated with a significant reduction in nerve conduction velocity in the optic nerve.

255 ct) techniques, such as electromyography and nerve conduction velocity measurement, do not reliably p

256 We detected reduced nerve conduction velocity of the left RLn, compared to t

257 l content was elevated (P < 0.001) and motor nerve conduction velocity reduced (P < 0.05) in galactos

258 All strategies prevented loss of nerve conduction velocity resulting from STZ-induced dia

259 rt internodal lengths and associated reduced nerve conduction velocity seen in the absence of periaxi

260 (R/S)-1 and (R)-1 partially prevented motor nerve conduction velocity slowing in a mouse model of ty

261 Upper limb motor nerve conduction velocity was 19.9 m/s +/- 1.3 (SEM), ra

262 Motor nerve conduction velocity was moderately reduced in the

263 young mice with short mutant Schwann cells, nerve conduction velocity was reduced and motor function

264 Caudal nerve conduction velocity was significantly slower in mi

265 erences in neurobehavioral assessments or in nerve conduction velocity when compared with children wh

266 d were associated with a 25-30% reduction in nerve conduction velocity, all of which were completely

267 itol supplementation on nerve Na+-K+-ATPase, nerve conduction velocity, and myelinated nerve fiber pa

268 onduction velocity, hindlimb digital sensory nerve conduction velocity, and sciatic nerve concentrati

269 eripheral neuropathy characterized by slowed nerve conduction velocity, axon loss, and distinctive my

270 inhibited a diabetes-induced defect in ulnar nerve conduction velocity, but neither agent was found t

271 TDs, produced significant deficits in caudal nerve conduction velocity, caudal amplitude and digital

272 DM, we observed that, in addition to reduced nerve conduction velocity, db/db mice also develop PNH.

273 Sciatic motor nerve conduction velocity, hindlimb digital sensory nerv

274 as determined by abnormal motor and sensory nerve conduction velocity, mechanical allodynia, and los

275 vere PMD, increased myelination and restored nerve conduction velocity, motor function and lifespan o

276 ozygous R98C animals, but it did not improve nerve conduction velocity, myelin thickness, G-ratios or

277 Transplantation significantly improved tail nerve conduction velocity, Na(+)-K(+)-ATPase activity, a

278 Effects of each drug on caudal and digital nerve conduction velocity, nerve amplitude, and sciatic

279 ow, significantly improved motor and sensory nerve conduction velocity, prevented the development of

280 layed maturation of nodes of Ranvier, slowed nerve conduction velocity, reduced muscle mass and reduc

281 Diabetes caused a decrease in nerve conduction velocity, thermal hypoalgesia, and a re

282 rats fed high-fat diets caused a decrease in nerve conduction velocity, thermal hypoalgesia, and intr

283 tions in sciatic motor and saphenous sensory nerve conduction velocity, which were 62 and 78% correct

284 e exhibit impaired motor function and slower nerve conduction velocity.

285 al hyperalgesia, cold allodynia, and sciatic nerve conduction velocity.

286 ich, in turn, has a significant influence on nerve conduction velocity.

287 nset of functional changes such as decreased nerve conduction velocity.

288 d progressive demyelination and a slowing of nerve conduction velocity.

289 ore there were any detectable alterations in nerve conduction velocity.

290 o results in a severe decrease in peripheral nerve conduction velocity.

291 elinating neuropathy and to severely reduced nerve conduction velocity.

292 es myelin outfoldings that impair the normal nerve conduction velocity.

293 x 10(-9)), indicating that INPP4B regulates nerve conduction velocity.

294 nd 21b,d all produce a reversible slowing of nerve-conduction velocity in the mice, the onset of whic

295 did not induce the phenomenon of slowing of nerve-conduction velocity.

296 collected included lead deployment success, nerve conduction, ventilation variables, work of breathi

297 trodotoxin-resistant sodium channel, sciatic nerve conduction was at least as sensitive to tetrodotox

298 logical evaluation of both sensory and motor nerve conduction was performed.

299 l examinations of P30 op/op mice showed that nerve conduction was significantly delayed but not block

300 This defect is associated with slowed nerve conduction, which could contribute to behavioral d