ライフサイエンスコーパス: neural circuit

1 l cholinergic motor neurons in the avoidance neural circuit.

2 eus of the amygdala to AT and its underlying neural circuit.

3 in the two modalities are formed in the same neural circuit.

4 rates functional synaptic specification in a neural circuit.

5 ter stroke is associated with a remapping of neural circuits.

6 tion causes to the computations performed by neural circuits.

7 ion allows silencing of specific hyperactive neural circuits.

8 -matrix adhesion could have implications for neural circuits.

9 hat work together to control the assembly of neural circuits.

10 uning in different visual category-selective neural circuits.

11 are supported by different computations and neural circuits.

12 teria participate in establishing functional neural circuits.

13 gy efficient instantiation of information in neural circuits.

14 onents of motor adaptation recruit different neural circuits.

15 strategies result from activity in distinct neural circuits.

16 anism that enables the maintenance of stable neural circuits.

17 hat innervate into and repopulate endogenous neural circuits.

18 ce, suggesting a "hard wiring" of underlying neural circuits.

19 plays an important role in the physiology of neural circuits.

20 n youths by identifying abnormalities within neural circuits.

21 work on experience-dependent modification of neural circuits.

22 to be critical for information processing in neural circuits.

23 on neurons interconnected in a vast array of neural circuits.

24 re typically attributed solely to developing neural circuits.

25 ively different types of solutions emerge in neural circuits.

26 or functions interfacing type 2 immunity and neural circuits.

27 uccessively change the properties of defined neural circuits.

28 an additional layer of dynamic complexity to neural circuits.

29 two prominent models of short-term memory in neural circuits.

30 pment, structure, function, and pathology of neural circuits.

31 e in determining the dynamical repertoire of neural circuits.

32 erstanding the computational capabilities of neural circuits.

33 orts to map and to functionally characterize neural circuits.

34 sses caused by molecular changes in specific neural circuits.

35 arning rule that utilizes noise intrinsic to neural circuits.

36 y in shaping the flow of information through neural circuits.

37 serve fundamental computational roles within neural circuits.

38 mapping the architecture of highly resolved neural circuits.

39 or the other process and their corresponding neural circuits.

40 direction signals computed and maintained in neural circuits?

41 structural and functional differences in the neural circuits accessed.

42 Assays of neural circuit activity demonstrated that disrupting mit

43 Cognitive rigidity imposed by neural circuit adaptations during nicotine abstinence ma

44 tivity that relate to tuning in a particular neural circuit also correlate to behavioral reaction tim

45 ugh in many cases adaptive, the capacity for neural circuit alteration also induces a state of vulner

46 anterograde trans-synaptic viral vectors for neural circuit analysis in multiple species.

47 ally and functionally defining cell types in neural circuit analysis, TrailMap will facilitate automa

48 n 129 (H129) are important tools for mapping neural circuit anatomic and functional connections.

49 ow the final action plan could emerge in the neural circuit and compared their implications with expe

50 se(s) control opioid actions in the relevant neural circuit and how they change in disease states to

51 m may participate in decision-making but the neural circuit and molecular bases for these functions a

52 itability, and firing rates, its role at the neural circuit and network level is unknown.

53 Observed differences at the neural circuit and protein levels provide insight into t

54 al development is essential for establishing neural circuits and a nervous system(1).

55 ure of juvenile critical period consolidates neural circuits and behavior, but this limits functional

56 To examine its significance for neural circuits and behavior, we examined the developmen

57 However, the exact neural circuits and cell types that mediate the suppress

58 To explore the link between underlying neural circuits and computational principles, we present

59 to form 'tripartite synapses', can modulate neural circuits and impact on synaptic organisation.

60 troduce a novel behavioral analysis to study neural circuits and mechanisms underlying action selecti

61 solutions, and review some of the underlying neural circuits and mechanisms.

62 Pathological degeneration of axons disrupts neural circuits and represents one of the hallmarks of n

63 in seconds or much longer timescales within neural circuits and shaping multiple behavioral outputs.

64 emarkable consequences for the maturation of neural circuits and stabilization of behavior.

65 informed by defined molecular mechanisms and neural circuits and targeted to the root cause of the pa

66 c and developmental programs that compromise neural circuits and yield a broad range of behavioral de

67 wever, controversy remains as to whether the neural circuits and, more specifically, the same neurons

68 l oscillatory activity in the STN-associated neural circuit, and these results highlight that the kin

69 gs support that H129-derived tracers map the neural circuit anterogradely and possibly transsynaptica

70 of compartmentalized activity for the wider neural circuit are often unclear.

71 pplications of transsynaptic AAV1 in probing neural circuits are described.

72 emains unclear whether the same or different neural circuits are engaged during periods of perceptual

73 d initially in the olfactory bulb (OB) where neural circuits are formed among inhibitory interneurons

74 te that sparse reconstituted rat hippocampal neural circuits are intrinsically capable of encoding an

75 However, the underlying neural circuits are not well defined.

76 ing embryonic development to form functional neural circuits are poorly understood.

77 evant sensory comparisons and the underlying neural circuits are still largely unknown.

78 dynamic recruitment that occurs within this neural circuit as the frequency is altered.

79 a dynamic reconfiguration of the underlying neural circuits as a function of sensory feedback from s

80 ance, the molecular mechanisms regulating DG neural circuit assembly and function remain unclear.

81 cam and dscaml1) are essential regulators of neural circuit assembly, but their roles in vertebrate n

82 ntified 20 cell-surface molecules regulating neural circuit assembly, many of which belong to evoluti

83 This indicates that neural circuits associated with target selection, such a

84 ve seen advances in our understanding of the neural circuits associated with trauma-related disorders

85 How the brain's affective neural circuits attribute this aversive quality to nocic

86 mammalian communication, but the underlying neural circuits await detailed characterization.

87 development, suggesting a mechanism whereby neural circuits begin as flexible systems that develop i

88 each other's computations in agent-specific neural circuits, but it is not known how circuits become

89 es for imaging the structure and dynamics of neural circuits, but the cell bodies of individual neuro

90 e often attributed exclusively to developing neural circuits, but the effects of postnatal body chang

91 g tissues is crucial to the establishment of neural circuits, but the underlying cellular and molecul

92 re thought to shape synaptic connections and neural circuits by acting in trans (spanning cellular ju

93 pses, explaining the anterograde labeling of neural circuits by H129-derived tracers.

94 facilitate detailed single-cell analysis of neural circuits by linking genetic identity, morphology,

95 limits on the possible computations a given neural circuit can perform.

96 Our study demonstrates generally that novel neural circuits can be identified from targeted connecto

97 Consequently, large neural circuits can either devote connectivity to genera

98 neracy and robustness.SIGNIFICANCE STATEMENT Neural circuits can generate nearly identical behavior d

99 oral disorders whose underlying cellular and neural circuit causes are not understood.

100 ssociated with autism spectrum disorders and neural circuit changes in several brain areas, but the c

101 experiences might produce lasting changes in neural circuits, Clayton [D.

102 e goal of resolving the relationship between neural circuits, cognitive processes and behavior.

103 eurons to restore the activity of intestinal neural circuits compromised by injury or disease.

104 is essential for understanding mechanisms of neural circuit computation.

105 uality, which, in turn, leads to a change in neural circuit connectivity and disruption of normal beh

106 Thus, our studies link specific neural circuit connectivity and function with stimulus d

107 e electrically coupled, thereby compromising neural circuit connectivity.

108 The way in which aberrant neural circuits contribute to epilepsy remains unclear.

109 network will shed light into how small-scale neural circuits contribute to higher cognitive functions

110 al behaviors are key steps to understand how neural circuits control behaviors.

111 d as a prominent model for understanding how neural circuits control visually guided behaviors.

112 fields (FEF(SEM)) is a critical node in the neural circuit controlling smooth pursuit eye movement.

113 kely caused or exacerbated by dysfunction of neural circuits controlling bladder function.

114 e ventral pallidum (VP) is a key node in the neural circuits controlling relapse to drug seeking.

115 Here we investigated how neural circuits controlling skilled reaching were affect

116 sented here provide strong evidence that the neural circuits conveying mechanical allodynia in the do

117 current interactions in a simple and modular neural circuit could create the dynamics needed to contr

118 based model of descending motor control how neural circuits could interact with changing laryngeal d

119 etic approach to selective activation of key neural circuits could provide a means of identifying neu

120 een established as a major mechanism driving neural circuit deconstruction and remodeling.

121 ntify demands that their execution places on neural circuit design, and propose a canonical neural ci

122 rts showing a role of autophagy during early neural circuit development and suggests that autophagy i

123 , sex differences in hormonal influences and neural circuit development result in biases in the circu

124 colonization of the brain to later regulate neural circuit development.

125 e neuroprotective factor Hif2a as underlying neural circuit differences in response to dopamine deple

126 e of day and show distinct sex and circadian neural circuit differences.

127 etween LM and EM, providing a new avenue for neural circuit discovery.

128 vioral data, and it is compatible with other neural circuit dissection tools for determining the mous

129 evel for differences in the motor production neural circuit during the progression of Parkinson's dis

130 cated in the establishment and refinement of neural circuits during development.

131 y clinical features of PD and their basis in neural circuit dysfunction.

132 to map competitive selection explicitly onto neural circuit elements.

133 To map neural circuits encoding bias, we administered a gamblin

134 merous places of the developing brain during neural circuit establishment.

135 d firing, which can have unwanted effects on neural circuits following inactivation, was not observed

136 t that the MD is a critical component of the neural circuit for interval timing, without playing a di

137 ll-specific ablation methods, we dissected a neural circuit for prolonged itch formed as Grpr(+) neur

138 hitecture and the evolutionary divergence of neural circuits for vocal communication.

139 arbor is adequately formed to enable proper neural circuit formation and function.

140 s synaptogenic wiring molecules that promote neural circuit formation by mediating the establishment

141 neuronal maturation is essential for proper neural circuit formation.

142 ht be broadly relevant for axon guidance and neural circuit formation.

143 during development are a fundamental step in neural circuit formation.

144 echanisms interact with one another to shape neural circuit formation.

145 ural circuit design, and propose a canonical neural circuit framework.

146 Together, our data reveal a neural circuit from VMH to PVT that inhibits food intake

147 pendent myelination is hypothesized to shape neural circuit function and subsequent behavioral output

148 cuit assembly, but their roles in vertebrate neural circuit function are still mostly unexplored.

149 suggest MALT1 has an ancient role modulating neural circuit function downstream of IL-17 to remodel p

150 trophysiology can reveal basic principles of neural circuit function in vivo and suggest an intuitive

151 Despite their importance for neural circuit function, only a little is known about th

152 c arbor in pyramidal neurons is critical for neural circuit function.

153 ut the brain and significantly contribute to neural circuit function.

154 nt cytokine interleukin-17 (IL-17) modulates neural circuit function.

155 visual deprivation, distributed word-related neural circuits 'grew into' the deprived visual areas, w

156 ial roles of fast-spiking neurons in various neural circuits have been widely recognized, it remains

157 on of synaptic connections required to shape neural circuits, however, relatively few specific miRNAs

158 f autoantibodies, microglial activation, and neural circuit impairment during postinfectious BGE.

159 We focus on two large-scale neural circuits implicated in sleep impairment and in mo

160 for speech and song learning are known, the neural circuits important for enhanced or reduced vocal

161 ol and other addictive substances can remold neural circuits important for memory to reduce this flex

162 he accessory olfactory bulb (AOB), the first neural circuit in the mouse accessory olfactory system,

163 ults, episodic memory involves a distributed neural circuit in which the hippocampus plays a central

164 iating the genetic specification of cephalic neural circuits in arthropods correspond to those in cho

165 ng the structural and functional dynamics of neural circuits in brain tissue, which is highly scatter

166 regulating neural signal transduction along neural circuits in CNS.

167 Here we investigate neural circuits in Drosophila that process proprioceptiv

168 time that the function of disorder-relevant neural circuits in generalized anxiety disorder can be b

169 ticity is a stabilizing mechanism engaged by neural circuits in response to prolonged perturbation of

170 Neural circuits in the adult nervous system are characte

171 summarises recently proposed theories on how neural circuits in the brain could approximate the error

172 its application could be in various types of neural circuits in the brain.

173 pportunity to understand the organization of neural circuits in the context of voluntary and natural

174 important roles in the development of other neural circuits in the developing brain.

175 Sensory experience remodels neural circuits in the early postnatal brain through mec

176 Leveraging well-characterized suppressive neural circuits in the visual system, we used behavioral

177 ts allows for sophisticated investigation of neural circuits in vivo, that would otherwise be impossi

178 ing open question is how astrocytes regulate neural circuits in ways that are behaviorally consequent

179 tic effects of RS67333 recruited an mPFC-DRN neural circuit, in vivo recordings of firing rate of DRN

180 ieve transcranial photoactivation of defined neural circuits, including midbrain and brainstem struct

181 Understanding how genes, drugs and neural circuits influence behavior requires the ability

182 ditis elegans have left still unresolved how neural circuits integrate and respond to neurotransmitte

183 We suggest that this darcin-activated neural circuit integrates pheromonal information with in

184 n onto a neuronal model of the ARTR, a small neural circuit involved in the orientation-selection of

185 ic- and antidepressant-like effects, but the neural circuits involved remain poorly understood.

186 The anatomy of many neural circuits is being characterized with increasing r

187 n excitation and inhibition (E-I balance) in neural circuits is believed to be tightly regulated.

188 Revealing the organization and function of neural circuits is greatly facilitated by viral tools th

189 ing of nonlinear stimulus transformations by neural circuits is hindered by the lack of comprehensive

190 this flexibility is achieved at the level of neural circuits is not understood.

191 tional abilities, such as working memory, in neural circuits is one of the most essential concerns in

192 technologies, the neuroscience of brain-wide neural circuits is poised to take off.

193 by a lack of differences on a subjective and neural circuit level.

194 has pleiotropic physiologic effects, but the neural circuits linking stress to these responses are no

195 (AHR) functions as a biosensor in intestinal neural circuits, linking their functional output to the

196 Recent development of methods for neural circuit manipulation allows silencing of specific

197 ize the viruses that have been developed for neural circuit mapping, and we provide a primer on curre

198 e demonstrate how this system can facilitate neural circuit-mapping in Drosophila.

199 sociability in adulthood, but the underlying neural circuit mechanisms are poorly understood.

200 uciatingly painful and yet the receptors and neural circuit mechanisms that transmit this form of pai

201 y, but it has been difficult to identify the neural circuit mechanisms that underlie persistent activ

202 However, specific, identifiable neural circuit mechanisms underlying the implementation

203 However, the neural circuit mechanisms underlying this ability are un

204 d mice opens a rich avenue for research into neural circuit mechanisms underlying this critical execu

205 to treat major depressive disorder, yet the neural circuit mechanisms underlying this therapeutic ef

206 kely, therefore, that further delineation of neural circuits mediating craniofacial muscle hyperalges

207 Neural circuits mediating exploratory behavior should th

208 ms for such transformation, we constructed a neural circuit model consisting of modules representing

209 y training a recurrent excitatory-inhibitory neural circuit model of a visual cortical hypercolumn to

210 Using a neural circuit model of decision uncertainty and change-

211 A neural circuit model of layer 2/3 revealed that recurren

212 ples, we present how a biologically detailed neural circuit model of the insect mushroom body impleme

213 urrent development of minimal behavioral and neural circuit models that can quantitatively capture ba

214 Our findings suggest that the same neural circuit modulates the drive for food search and f

215 mmalian nervous system and survey functional neural circuit motifs enabled by these synapses.

216 Excitation in neural circuits must be carefully controlled by inhibiti

217 ese computations and their implementation in neural circuits, natural behavior must be carefully meas

218 Here, we find symmetries in the locomotion neural circuit of C. elegans, each characterized by its

219 How experience impinges on the developing neural circuits of behavior is an open question.

220 The circadian neural circuits of diurnal/day- and nocturnal/night-biti

221 Stereotyped synaptic connections define the neural circuits of the brain.

222 esize that the amygdala, a core component of neural circuits of threat processing, is involved in pro

223 visual) can interact and drive plasticity in neural-circuits of the primary visual cortex (V1).

224 Information flow through neural circuits often requires their organization into t

225 ty in shaping the spatiotemporal dynamics of neural circuit operations underlying cognition.

226 Imaging neurons and neural circuits over large volumes at high speed and sub

227 nges in multiple neuronal subtypes and their neural circuits over prolonged periods of drug treatment

228 dendritic patterning and cell-intrinsic and neural circuit physiology of the hippocampus and prefron

229 n or inhibition of the responsible olfactory neural circuit promotes the loss or gain of fat storage,

230 hat synaptic and electrical integration into neural circuits promotes glioma progression.

231 c, theoretical, and computational studies of neural circuits provides new perspectives to understand

232 Their contributions to the neural circuit providing input to parasol cells are not

233 How neural circuits reconfigure themselves according to the

234 Auditory experience drives neural circuit refinement during windows of heightened b

235 ecular players that regulate mitochondria in neural circuits regulating anxiety and depression and ab

236 rate that general anesthetics can co-opt the neural circuits regulating arousal to produce unconsciou

237 physiological functions of astrocytes within neural circuits remain incompletely understood.

238 ment of threat responding and the underlying neural circuits remains limited.

239 How astrocytes grow and integrate into neural circuits remains poorly defined.

240 em, but how injury signals are spread across neural circuits remains unclear.

241 l injury, such as stroke, is associated with neural circuit reorganization, but the underlying mechan

242 oton imaging of soma-targeted GCaMP in dense neural circuits reported fewer artifactual spikes from n

243 mosquitoes possess the central or peripheral neural circuits required to host-seek and that removing

244 Understanding neural circuits requires deciphering interactions among

245 Precise analysis of complex neural circuits requires high-density integration of mul

246 , however, about the specific cell types and neural circuits responsible for these diverse functions.

247 However, the neural circuits responsible for this flexible processing

248 Augur identified the neural circuits restoring locomotion in mice following s

249 -1 neuropeptide released from this olfactory neural circuit signals through peripheral NPR-4/neuropep

250 el for understanding GPCR signaling in other neural circuits.SIGNIFICANCE STATEMENT Neurotransmitters

251 Nevertheless, the functioning of the neural circuits supporting spatial processing have yet t

252 possibility that the up-regulation of these neural circuits supports mentalizing, reminiscence and i

253 We modeled a neural circuit that accounts for diverse experimentally-

254 Using the sensory-motor neural circuit that contributes to learning in defensive

255 A new study identifies a neural circuit that controls rejection and shows how it

256 ining genes, fruitless (fru), belongs to the neural circuit that generates male-type aggressive behav

257 tes of AT in NHPs has revealed a distributed neural circuit that is linked to individual differences

258 al key molecular components of a peptidergic neural circuit that supports breathing at a particularly

259 roach to map parasympathetic and sympathetic neural circuits that control heart rate in mice.

260 ibly reconfigure the ongoing dynamics in the neural circuits that control movements.

261 spinal cord is an important component of the neural circuits that control penile reflexes in rats, ci

262 complex, the functional neuroanatomy of the neural circuits that generate expiration is debated.

263 uch remains unknown regarding the underlying neural circuits that govern initial ethanol intake.

264 rly prenatal brain development, particularly neural circuits that later develop specialized roles in

265 ome enduring imprint on our brains, altering neural circuits that mediate behavior and contributing t

266 is an ancient one, developed through shared neural circuits that on one hand teach us how to value t

267 In neuroscience, data-driven models of neural circuits that span multiple scales are increasing

268 Body weight is regulated by interoceptive neural circuits that track energy need, but how the acti

269 ntribute to the maturation and plasticity of neural circuits that ultimately shape behavior.

270 Neural circuits that underlie aggressive behavior are th

271 , and distinct gene profiles are observed in neural circuits that underlie beacon discrimination perf

272 distinct roles these cell types play in the neural circuit, the molecular correlates remain unknown

273 However, without inhibition of the recruited neural circuits, the observer would perform the correspo

274 mics have been observed in various recurrent neural circuits, the role recurrent circuitry plays in i

275 t to directly measure the wiring diagrams of neural circuits, there has long been an interest in esti

276 Control of electrical activity in neural circuits through network training is a grand chal

277 Dopamine powerfully controls neural circuits through neuromodulation.

278 sses light and gravity cues through a simple neural circuit to decide when and how to swim.

279 during which high levels of plasticity allow neural circuits to be tuned for optimal performance.

280 with the physiological output of intestinal neural circuits to maintain gut homeostasis and health.

281 Which neural circuits undergo synaptic changes when an animal

282 al subtype, embedded in both mouse and human neural circuits, undergo remarkably similar activity-dep

283 hese findings provide novel insight into the neural circuit underlying innate predator defense.

284 In addition, we elucidated the neural circuit underlying this avoidance behavior, and w

285 ion effect." We identified three layers of a neural circuit underlying this phenomenon.

286 Although the neural circuits underlying more direct forms of learning

287 We examined neural circuits underlying partially reinforced fear (PR

288 and anxiety symptoms, the identification of neural circuits underlying psychological constructs with

289 his project extends our understanding of the neural circuits underlying resistance to acute social st

290 Progress has been made in understanding the neural circuits underlying the "engram" of threat or fea

291 sex differences in these processes, and the neural circuits underlying them.

292 help catalyze experimental discovery of the neural circuit underpinnings of competitive selection.

293 r GPCRs together help regulate function of a neural circuit, we analyzed the simple egg-laying circui

294 Neural circuits which process sensory information must t

295 sed by a reduction in signal-to-noise in key neural circuits, which could be the result of changes in

296 demonstrates new approaches for training of neural circuits whose electrical activity can be modulat

297 nd when they influence the operations of the neural circuits with which they interact.

298 evelopmental stage, anatomical locus and the neural circuit within which synapses reside.

299 mechanisms by which LLTS affect the central neural circuits within the brain regions that are import

300 ing GABAergic transmission and disinhibiting neural circuits within the neurogenic niche, suggesting