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1 let-7 knock down shortens the cell cycle in neural progenitors.
2 is required for apical nuclear migration in neural progenitors.
3 e differentiation of embryonic stem cells to neural progenitors.
4 n reprogram developing wing discs into brain neural progenitors.
5 of promoting the proliferation of embryonic neural progenitors.
6 rons by knockout of betaII-spectrin in mouse neural progenitors.
7 ients overproduce OLIG2(+) ventral forebrain neural progenitors.
8 embryonic origin and establishment of adult neural progenitors.
9 t, neurons are produced by a diverse pool of neural progenitors.
10 n in mice, by controlling proper division of neural progenitors.
11 g cells, which represent enteric glia and/or neural progenitors.
12 orphogen input to the positional identity of neural progenitors.
13 expression in Drosophila embryonic or larval neural progenitors.
14 ouse embryonic stem cells and differentiated neural progenitors.
15 e used to identify a source of GDNF-targeted neural progenitors.
16 ult stem/progenitor cell, called adult human neural progenitor (AHNP) cells, that we found to be path
17 PEN is dispensable for maintenance of XCI in neural progenitors, although it significantly decreases
18 and D2R signaling on SVZ cell proliferation, neural progenitor and neuronal maturity is differentiall
19 (i) studying their biological role in human neural progenitors and (ii) incorporating TF conditional
21 argets in human dorsal and ventral forebrain neural progenitors and excitatory and inhibitory neurons
22 cell types were identified as proliferating neural progenitors and immature neurons, both of which c
25 intermediate filament expressed strongly in neural progenitors and is thus used widely as a progenit
26 he constitutively active PKM1 isoform, while neural progenitors and medulloblastomas exclusively expr
27 vity, induce ectopic RNA-protein granules in neural progenitors and neurons, and impair translation.
29 ine the need for MCT8-dependent TH uptake in neural progenitors and stress the importance of local TH
30 brate neural tube determines the identity of neural progenitors and the function and physiology of th
31 transition of undifferentiated P19 cells to neural progenitors and their ultimate terminal different
33 esioned site and (b) in the proliferation of neural progenitors, arguing for a neuroprotective role o
34 dentify impaired differentiation of specific neural progenitors as a common mechanism underlying thes
35 Here we identify a brain-region-specific neural progenitor-based signaling pathway dedicated to r
36 treatment had a pro-proliferative effect on neural progenitors, but neuronal integration occurred on
37 Nestin expression is thus not restricted to neural progenitors, but persists for 2-3 d at lower leve
39 ted by fusion of human iPSC-derived cortical neural progenitor cell (iNPC) spheroids, endothelial cel
40 exhibited neurodevelopmental defects due to neural progenitor cell (NPC) apoptosis, which led to red
42 ing cellular functions of LIS1 in regulating neural progenitor cell (NPC) daughter cell separation.
43 this purpose, we adapted a system to induce neural progenitor cell (NPC) development from mouse embr
44 tested the hypothesis whether disturbance of neural progenitor cell (NPC) differentiation into the ol
45 nction between isogenic wild-type and mutant neural progenitor cell (NPC) lines revealed increased ox
46 ssesses a mitotically active, age-depletable neural progenitor cell (NPC) niche, with unique characte
48 cortex development through the regulation of neural progenitor cell (NPC) proliferative and different
50 Science, Chavali et al. (2017) identified a neural progenitor cell (NPC)-specific RNA binding protei
51 estions regarding its role as a regulator of neural progenitor cell cycle progression in cerebellar d
54 oral functional outcome of RAF1 during mouse neural progenitor cell differentiation using an optogene
55 occurs in Down syndrome, is known to affect neural progenitor cell differentiation, while haploinsuf
56 hat complement-derived peptide C3a regulates neural progenitor cell migration and differentiation in
58 critical function in regulation of postnatal neural progenitor cell production in response to Noggin.
60 l module, confirming that these genes reduce neural progenitor cell proliferation and neurite growth.
61 rmone receptor alpha1 is required for normal neural progenitor cell proliferation in human cerebral c
62 receptor signaling is sufficient to increase neural progenitor cell proliferation in the absence of f
63 ver, the effects of nutrient availability on neural progenitor cell proliferation in vivo are poorly
65 de anion scavenger during IH did not prevent neural progenitor cell proliferation, it mitigated the I
68 ration and neurogenesis of adult hippocampal neural progenitor cells (AHNPCs) and in a non-cell auton
69 euronal differentiation of adult hippocampal neural progenitor cells (AHNPCs) following environmental
70 transcellular transmission in differentiated neural progenitor cells (dNPCs) and neuroblastoma SH-SY5
71 ntifying strategies to optimize iPSC-derived neural progenitor cells (hiNPC) for cell transplantation
72 human pluripotent stem cell-derived cortical neural progenitor cells (hNPCs) and found that hippeastr
74 Human induced pluripotent stem cell-derived neural progenitor cells (hNPCs) are a promising cell sou
76 lateral prefrontal cortex and cortical human neural progenitor cells (hNPCs) was determined using imm
79 lanted induced pluripotent stem cell-derived neural progenitor cells (iPS-NPCs) could recapitulate an
80 Using induced pluripotent stem cell-derived neural progenitor cells (iPS-NPCs) expressing the novel
82 ular endothelial cells (PVEC) crosstalk with neural progenitor cells (NPC) promoting mutual prolifera
83 h a mean age of 90.6 years, Nestin(+)Sox2(+) neural progenitor cells (NPCs) and DCX(+) neuroblasts an
84 sed ZIKV infectivity in both human and mouse neural progenitor cells (NPCs) and led to more severe mi
85 to generate induced pluripotent stem cells, neural progenitor cells (NPCs) and neurons from ASD indi
87 ion of murine embryonic stem cells (ESCs) to neural progenitor cells (NPCs) and recruits the Mediator
88 othesized that METH impacts HIV infection of neural progenitor cells (NPCs) by a mechanism encompassi
90 neural differentiation, the HD-iPSC-derived neural progenitor cells (NPCs) demonstrated lower levels
92 d induced pluripotent stem cells (iPSCs) and neural progenitor cells (NPCs) derived from individuals
97 ry behavior and differentiation potential of neural progenitor cells (NPCs) found in the subventricul
98 d how a regenerative program is fulfilled by neural progenitor cells (NPCs) of the spinal cord, we an
99 induced pluripotent stem (iPS) cell-derived neural progenitor cells (NPCs) to repair the FTD-associa
100 ity of uCPP 3D-printed scaffolds loaded with neural progenitor cells (NPCs) to support axon regenerat
103 rains and organoids due to the disruption of neural progenitor cells (NPCs), including outer radial g
104 educes spread and output of ZIKV in infected neural progenitor cells (NPCs), the major cells infected
105 n the collective dynamics of cultured murine neural progenitor cells (NPCs), which are multipotent st
106 roliferation and impaired differentiation of neural progenitor cells (NPCs), which resemble neurodeve
114 DISC1 interactomes within iPSC-derived human neural progenitor cells and astrocytes are able to provi
117 Patient-derived disease models including neural progenitor cells and cerebral organoids showed th
119 markers in young neurons derived from human neural progenitor cells and human induced pluripotent st
120 tes that an increase in the proliferation of neural progenitor cells and hyper-expansion of cortical
121 ex in wild-type and bi-allelic mutant ACTL6B neural progenitor cells and neurons revealed increased g
124 ome in regulating the mechanical features of neural progenitor cells and the size and configuration o
126 ition, the DISC1 interactome in iPSC-derived neural progenitor cells associates in a connected networ
127 zed four distinct types of Tc-foxQ2 positive neural progenitor cells based on differential co-express
129 how differential migration patterns in human neural progenitor cells compared to those of chimpanzees
130 d depression-like behaviors, suggesting that neural progenitor cells contribute to the effects of BMP
131 Parkinson's disease (PD) tissue sources: (a) neural progenitor cells derived from an endogenous adult
133 an counteract DISC1 deficiencies observed in neural progenitor cells derived from induced pluripotent
137 Knl1 deletion, segregation errors in mitotic neural progenitor cells give rise to DNA damage on the m
140 ncreased the number of proliferating Sox2(+) neural progenitor cells in the subgranular zone yet redu
141 uce and control directional axon growth from neural progenitor cells in vitro and host axons in a rat
142 ll markers and Notch target genes in primary neural progenitor cells in vitro Consistent with this, i
143 ctors (SOX10, OLIG2, NKX6.2) in iPSC-derived neural progenitor cells is sufficient to rapidly generat
144 cly available dataset of Zika virus-infected neural progenitor cells is used to illustrate AIDD's cap
146 e been explored, we focus here on the use of neural progenitor cells obtained or derived from differe
147 al that in the embryo, disc1 is expressed in neural progenitor cells of the hypothalamus, a conserved
148 settings, such as in vitro HCMV infection of neural progenitor cells or in vivo murine CMV infection
149 ZIKV causes productive replication, infects neural progenitor cells over mature neurons, decreases b
150 tion after 72 hours, preferentially infected neural progenitor cells over mature neurons, reduced bot
151 t early light-induced OptoRAF1 activation in neural progenitor cells promotes cell proliferation and
153 ta from GBM stem-like cells, astrocytes, and neural progenitor cells that are sensitive or resistant
154 glial progenitor cells (RGPs) are the major neural progenitor cells that generate neurons and glia i
157 nuclear YAP1 (nlsYAP5SA) in ventricular zone neural progenitor cells using conditionally-induced NEX/
158 whether CHD7 promotes gene transcription in neural progenitor cells via changes in chromatin accessi
160 model of spinal cord injury, in which human neural progenitor cells were transplanted at the site of
161 mouse embryogenesis drives proliferation of neural progenitor cells within the ventricular zone and
162 tly increased CNTF and BMP4 transcription in neural progenitor cells, and a neutralizing antibody aga
164 NA levels of Sox1 and Nestin, the markers of neural progenitor cells, and decreased the count of Sox1
165 vival, proliferation, and differentiation of neural progenitor cells, and suggest a basis for its fun
167 proteins at the base of the primary cilia in neural progenitor cells, causing an atypical non-genetic
168 velopment in a cell type-specific manner: In neural progenitor cells, GPR56 regulates cortical lamina
169 n was examined in neurons derived from human neural progenitor cells, human induced pluripotent stem
170 n (H3K4me2) in EPO treated and control fetal neural progenitor cells, identifying 1,150 differentiall
173 add to recent evidence in embryonic stem and neural progenitor cells, suggesting a model whereby deve
174 ll survival-based cDNA expression screens in neural progenitor cells, we identify a genetic variant o
175 ablishing the proper expression signature of neural progenitor cells, while catalytic inactivation of
190 re phenotypically normal, differentiation to neural progenitors cells (NPCs) was severely impaired.
191 e subjected to neonatal stroke and postnatal neural progenitor cultures, and we analyzed Olig1 expres
192 iR-199 or miR-214 expression in iPSC-derived neural progenitors deficient in MeCP2 restored AKT and E
194 ker genes, distinguishing five major groups: neural progenitors, differentiated neurons, glia, undiff
196 r-derived cells showing either a spectrum of neural progenitor-differentiation states or glial and st
198 ion into Hopx(+) quiescent radial glial-like neural progenitors during an early postnatal period.
199 hannels are key regulators of the biology of neural progenitors during development and in adult neuro
201 nes to control the proliferative capacity of neural progenitors, ensuring the generation of correct n
204 mbryonic, early postnatal, and adult dentate neural progenitors further reveal common molecular and e
206 elayed OptoRAF1 activation in differentiated neural progenitor had little effect on glia marker expre
208 x2 homeodomain transcription factor promotes neural progenitor identity in the lateral ganglionic emi
210 absence of BubR1 decreases the proportion of neural progenitors in mitosis, specifically in metaphase
212 rol the proliferation and differentiation of neural progenitors in the adult hippocampal dentate gyru
213 PlexinC1 is selectively expressed in early neural progenitors in the adult mouse DG and mediates th
216 day 11.5 give rise to proliferative Hopx(+) neural progenitors in the primitive dentate region, and
217 altered, 2) the population of proliferating neural progenitors in the SVZ was reduced, whereas the p
218 Depletion of Zfp609 or Nipbl from cortical neural progenitors in vivo is detrimental to neuronal mi
219 The Blbp-Cre driver that targets embryonic neural progenitors induced tumors exhibiting a large-cel
220 opulation of transit-amplifying intermediate neural progenitors (INP) similar to that found in the de
221 multiple transiently amplifying intermediate neural progenitors (INPs) from a single neural stem cell
222 the developmental potential of intermediate neural progenitors (INPs) generated by asymmetrically di
224 euroblasts generate a series of intermediate neural progenitors (INPs) that each produce 4-6 GMCs and
225 n of doublecortin-positive adult hippocampal neural progenitors into functionally mature neurons.
226 ndicate that MCT8-dependent TH uptake in the neural progenitors is essential for early events in cort
227 induced pluripotent stem cells to forebrain neural progenitors is markedly reduced, but mutant proge
228 that the major effect of BubR1 deficiency on neural progenitors is to impair the mitotic checkpoint.
229 fective proliferation and differentiation of neural progenitors is unlikely the single underlying cau
232 cortex is populated by neurons derived from neural progenitors located throughout the embryonic tele
233 unofluorescence for established neuronal and neural progenitor marker proteins and compared the resul
234 xpressed higher levels of key ectodermal and neural progenitor markers and lower levels of markers fo
235 ed self-organization of neuruloids harboring neural progenitors, neural crest, sensory placode and ep
236 tterning mechanisms discovered in Drosophila neural progenitors (neuroblasts) involve progenitor-intr
238 n human pluripotent stem cell (hPSC)-derived neural progenitors (NPs) using a genome-wide CRISPR-Cas9
239 buprofen-treated mice that display increased neural progenitor numbers (Ki67 positive) in the subvent
240 Here, we show that proliferating cortical neural progenitors of human embryonic brains highly expr
242 vivo RNAi vector-based knockdown of MCT8 in neural progenitors of the chicken optic tectum, a layere
244 urther show that MSI1 is highly expressed in neural progenitors of the human embryonic brain and is m
246 rly, 5hmC is enriched in neurons compared to neural progenitors of the ventricular zone in the mouse
247 at the microRNA (miRNA) let-7 accumulates in neural progenitors over time throughout the developing C
248 g to increased cell death, which reduces the neural progenitor pool and severely disrupts brain devel
250 upport a "continuous" model wherein a common neural progenitor population exclusively contributes to
252 egulator PRDM16 is expressed by radial glia, neural progenitors present in both regions; however, its
253 the level and activity of let-7 oscillate as neural progenitors progress through the cell cycle by in
254 hould be intermittent in order to first make neural progenitors proliferate and then, upon discontinu
255 , we evaluated adult neurogenesis, including neural progenitor proliferation and dendrite development
256 sion of mutant DISC1 in astrocytes decreased neural progenitor proliferation and dendrite growth of n
257 UB1B mutation, how BubR1 deficiency disturbs neural progenitor proliferation and neuronal output and
258 he H3K9me2 demethylase PHF2 is essential for neural progenitor proliferation in vitro and for early n
259 ure to rats during the most active period of neural progenitor proliferation induces cytoarchitectura
260 dpoles enter a period of stasis during which neural progenitor proliferation is drastically reduced,
261 he complement activation peptide C5a and the neural progenitor proliferation underpinning formation o
264 ore, compounds 5 and 14 were able to promote neural progenitors proliferation and drive their differe
265 ed with ibuprofen showed increased levels of neural progenitors proliferation and synaptic markers su
266 required for expansion of cerebellar granule neural progenitors, proposed to be cells-of-origin for t
267 s abnormal gene expression in early-stage DS neural progenitors, reduces interneuron production in DS
270 kout offspring show microcephaly and primary neural progenitors require Cep55 and ESCRT for survival
271 und that GOF disrupts mitosis of radial-glia neural progenitors (RGCs), inside-out radial migration o
272 underlying mechanism, demonstrating that LV-neural progenitors secrete a pleiotrophin (PTN)-containi
274 aracterization indicates that most embryonic neural progenitor states are transitory and transcriptio
276 s newly discovered extrinsic cues regulating neural progenitor temporal identity in Drosophila, highl
277 ifferentiate from transcriptionally distinct neural progenitors that are arrayed in discrete domains
278 fferentiation and the proliferative state of neural progenitors through regulation of the cytoskeleto
280 n is both dependent on Cre and restricted to neural progenitors, thus circumventing the aforementione
282 neurosphere-based culture enabled directing neural progenitors to adopt a specific cortical identity
283 demonstrate that nutrient restriction causes neural progenitors to arrest in G2 of the cell cycle wit
285 trajectories reveals that late-stage retinal neural progenitors transcriptionally overlap cell states
287 trocytes generated from regionally specified neural progenitors under the same conditions strongly im
290 t of p75(NTR) from embryonic day 10 (E10) in neural progenitors using a conditional Nestin-Cre p75(NT
291 ch signalling maintains Hh responsiveness of neural progenitors via a Gli-dependent mechanism in the
293 acute hyperglycemia, later proliferation of neural progenitors was significantly decreased by chroni
294 filament protein widely used as a marker of neural progenitors, was recently found to be expressed t
295 mediate filament protein highly expressed in neural progenitors, was recently identified in developin
296 nd preferences for three types of endogenous neural progenitors, we provide evidence for the differen
299 neurogenesis to direct apoptosis in cycling neural progenitors, whereas ATM regulated apoptosis in b
300 human induced pluripotent stem cell-derived neural progenitors, which were subsequently differentiat