ライフサイエンスコーパス: neural-specific

1 ng protein SCG10 (superior cervical ganglia, neural specific 10) was found to directly interact with

2 SCG10 (superior cervical ganglia neural-specific 10 protein) is a neuron specific member

3 Neural-specific ablation of C9orf72 in conditional C9orf

4 A neural-specific activating subunit, p35, of cyclin-depen

5 e present study shows that Cdk5 bound to its neural specific activator p35 not only binds to Munc-18

6 immediate 3' flanking sequence produce full neural specific activity that is down-regulated by GABA

7 The tuba1a gene encodes a neural-specific alpha-tubulin isoform whose expression i

8 ated B(DeltaI)/B(DeltaI) mice by replacing a neural-specific alternative exon with the PGK-Neo casset

9 reveal how coordinated miRNA regulation and neural-specific alternative polyadenylation (APA) of a s

10 r target of the analgesic acetaminophen is a neural-specific, alternatively spliced isoform of cycloo

11 ntify independent and opposing roles for two neural-specific and differentially expressed non-coding

12 partate (NMDA) receptor 2B (NR2B) subunit is neural-specific and differentially regulated.

13 y probe ADARs, harnessing brain organoids as neural specific, and teratomas as pan-tissue development

14 n cells retain their neural fate and express neural-specific antigens.

15 previously available models to further study neural-specific aspects of CS.

16 The NEUROGENINS (NGNs) are neural-specific basic helix-loop-helix (bHLH) transcript

17 MATH1 is a neural-specific basic helix-loop-helix transcription fac

18 c and cDNA mouse and human clones encoding a neural-specific bHLH protein, human BHLHB5 was cloned an

19 on of the Hes5 and Mash1 genes, which encode neural-specific bHLH proteins, decrease and increase, re

20 Mash1, a neural-specific bHLH transcription factor, is essential

21 Neural-specific, but not skeletal muscle-specific, delet

22 Neurogranin/RC3 is a neural-specific Ca(2+)-sensitive calmodulin (CaM)-bindin

23 The type I adenylyl cyclase (I-AC) is a neural-specific, Ca2+-stimulated enzyme that couples int

24 Neurogranin is a neural-specific, calmodulin (CaM)-binding protein that i

25 tion and expression in chromaffin cells of a neural specific Cdk5 activator, p25, led to a strong inc

26 Nectin-like 1 (Necl-1) is a neural-specific cell adhesion molecule that is expressed

27 transcriptomics data to infer and visualize neural-specific cell-cell communication.

28 ciliary network presents a wealth of new and neural-specific ciliary signaling proteins and yields ne

29 the inference, visualization and analysis of neural-specific communication networks among pre-defined

30 By using neural specific conditional mouse mutants, we show that

31 e isomerase-like protein that may bind TH, a neural-specific cytoskeletal protein, and two hypophysio

32 Here we show that neural-specific deletion of FIP200 resulted in cerebella

33 Mice with a neural-specific deletion of paxillin are also postnatal

34 We report that neural-specific deletion of sirtuin 6 (Sirt6) in mice le

35 Here we show that neural-specific deletion of the BTB/POZ zinc-finger tran

36 blasts from the cell cycle and expression of neural-specific differentiation markers.

37 To address this, we created mice with a neural-specific disruption of STAT3 (STAT3(N-/-)).

38 Despite a neural-specific down-regulation of adr-2 during developm

39 emethylation was essential for commissioning neural-specific enhancers in proximity to master neurode

40 transgenic mice that express FAAH under the neural specific enolase promoter.

41 enhancer from the developmentally regulated neural-specific esrrga gene.

42 Therefore, neural-specific exon 5 splicing and depletion of BAK1 pr

43 Splicing of neural-specific exons is differentially regulated in neu

44 s that are necessary and sufficient to drive neural-specific expression during gastrulation in transg

45 own for any vertebrate gene how the onset of neural-specific expression in early gastrula embryos is

46 Neural-specific expression of the mouse regulatory type-

47 to increase TRIM46 proteins, leading to its neural-specific expression.

48 al visual system) is a key mediator of these neural-specific extensions.

49 a calmodulin binding protein thought to be a neural-specific factor involved in learning and memory.

50 of small "Z" exons in Agrin, resulting in a neural-specific form of this extracellular proteoglycan

51 To investigate neural-specific functions of ERK2 in the brain, we used

52 data thus suggest that CSPP1 is involved in neural-specific functions of primary cilia.

53 contains specific recognition sites for two neural-specific GAP-43 mRNA-binding proteins.

54 ional MAPK pathways in NGF induction of this neural specific gene.

55 Interestingly, expression of one neural-specific gene (synaptobrevin), which is normally

56 orly understood small transmembrane proteins neural-specific gene 1 and 2 (Nsg1/NEEP21 and Nsg2/P19).

57 cription factors in CRMs faithfully predicts neural-specific gene activity.

58 oss-of-function mutations in CTNND2 target a neural-specific gene and are associated with the transfo

59 critical role in the activation of anterior neural-specific gene expression and that alkalinization

60 Injected Xski RNA was able to induce neural-specific gene expression directly in ectodermal e

61 First, RT-PCR was used to examine neural-specific gene expression in planar explants in wh

62 hich interruption of BMP signaling activates neural-specific gene expression is not understood.

63 Second, neural-specific gene expression was examined in isolates

64 ha gene could represent the first identified neural-specific gene induced by TR4.

65 re identified and the expression of the most neural-specific gene, Sof-elav1, was characterized durin

66 by directly targeting an extensive array of neural-specific genes as well as genes of developmental

67 le genes, it also precludes the induction of neural-specific genes by regulating the expression of PR

68 ifying complexes to repress transcription of neural-specific genes during early development.

69 Mesodermal and neural-specific genes were not expressed in cultured ani

70 es and an additional 24.4% (11/45) were from neural-specific genes, demonstrating the utility of this

71 inal targets for these signaling pathways in neural-specific genes.

72 on and cell fate, as well as other essential neural-specific genes.

73 differential nascent expression (Bru-Seq) of neural-specific genes.

74 Gli3 binds inertly to previously identified neural-specific Gli enhancers, demonstrating the accessi

75 ugh a non-neural toll-like receptor, linking neural-specific glycan expression to a kinase activity t

76 on of Tollo/Toll-8 into null embryos rescues neural-specific glycan expression.

77 duces a pattern of incompletely defined, but neural specific, glycan expression in the Drosophila emb

78 To explore how loss of GM3 impacts neural-specific glycolipid glycosylation and cell signal

79 However, mechanisms controlling embryonic neural-specific glycosylation are unknown.

80 haracterization of a mutation that abolishes neural-specific glycosylation in the Drosophila embryo d

81 l cells are deficient in PTB, they express a neural-specific homologue of PTB (nPTB).

82 Here we report that neural-specific inactivation of two murine post-transcri

83 Using murine neural-specific inactivation of Xrcc1, a factor that is

84 ins in the CNS, we provide evidence that the neural-specific interpretation of morphogen signaling re

85 paradigm appears to conceptually explain the neural-specific interpretation of pleiotropic signaling

86 two ways through which DLK is coupled to the neural-specific isoform JNK3 to control prodegenerative

87 ase in the immunohistochemical signal of the neural-specific isoform of Neuroglian, which is generate

88 ein) conditional-null allele and showed that neural-specific knockout of nucleostemin predisposes emb

89 ll, Ramos et al. (2015) demonstrate that the neural-specific lncRNA Pnky regulates neuronal different

90 Here, we identify Pinky (Pnky) as a neural-specific lncRNA that regulates neurogenesis from

91 propriate maintenance of Polycomb binding at neural-specific loci over the course of differentiation.

92 , as they are fully abrogated in mice with a neural-specific loss of function of HDAC6.

93 We used antibodies against the neural specific markers Hu C/D, neurofilament, and SV2 t

94 d de novo generation of cells that expressed neural-specific markers and exhibited neuronal morpholog

95 nant-negative GSK3 induces the expression of neural-specific markers and inhibits the expression of B

96 he time taken for the onset of expression of neural-specific markers.

97 ical division and the onset of expression of neural-specific markers.

98 These findings define a neural-specific mechanism of cell death whereby Pin1 cou

99 HuC is a neural-specific member of the Elav family of RNA-binding

100 Munc18-1, a neural-specific member of the Sec1/Munc18 protein family

101 specific RNA-binding proteins comprise three neural specific members called HuD, HuC, and Hel-N1.

102 However, the role of the neural-specific members HuB, HuC, and HuD (ELAVL2-4) in

103 Syntaxin1A, a neural-specific N-ethylmaleimide-sensitive factor attach

104 , C-SRC, to yield the constitutively active, neural-specific N1-SRC kinase.

105 n all Nogo isoforms that can interact with a neural-specific Nogo-66 receptor, the receptor for the a

106 als with mutations in MeCP2 may underlie the neural-specific pathology of RTT.

107 s and substrates contribute to the primarily neural-specific phenotype of OGT-CDG.

108 isms by which MeCP2 dysfunction leads to the neural-specific phenotypes of RTT remain poorly understo

109 d after intracerebroventricular injection in neural-specific POMC-deficient (Pomc(-/-)Tg/+) and globa

110 The same cells express phc2, a neural specific prohormone convertase, which suggests th

111 Drosophila melanogaster neural-specific protein, ELAV, has been shown to regulat

112 s a competition between HuR and the related, neural-specific proteins HuB and HuD.

113 ctor pathways in NIH3T3 fibroblasts for this neural-specific Ras family member.

114 cope variants were preferentially located in neural-specific regulatory regions.

115 We have isolated the gene that encodes the neural-specific RNA binding protein HuD in the mouse (El

116 elav-like neuronal protein 1) gene encodes a neural-specific RNA binding protein that is expressed in

117 the determinants required to recreate proper neural-specific RNA processing seen with the endogenous

118 globin), a partial functional homolog, whose neural-specific role is poorly defined.

119 The vertebrate and neural-specific Ser/Arg (SR)-related protein nSR100/SRRM

120 put as a context-specific determinant of the neural-specific Shh response and differential Gli-bindin

121 attenuation of apoptosis competence through neural-specific splicing of the Bak1 microexon is essent

122 ssed in neural cells and is required for the neural-specific splicing of the c-src N1 exon.

123 g regulator PTBP1 in immature neurons allows neural-specific splicing of the evolutionarily conserved

124 rotein, ELAV, has been shown to regulate the neural-specific splicing of three genes: neuroglian (nrg

125 n mesodermal cells the potential to activate neural-specific target genes upon Shh, retinoid, or bone

126 Alpha1-tubulin expression occurs in a neural-specific, temporally regulated, and regeneration-

127 Thus, XBF-1 is a neural-specific transcription factor that can independen

128 Herein, we discovered that the neural-specific transcription factor, Engrailed 1 (EN1),

129 Wild-type mouse nodes strongly induce the neural-specific transcription factors Sox2 and Sox3 in t

130 factor 1 (NZF-1) is a member of a family of neural-specific transcription factors that contain multi

131 udes the first exon, is sufficient to direct neural-specific transcription.

132 or proper regulation of a Deformed-dependent neural-specific transcriptional enhancer.

133 In addition, two neural-specific transcripts, GAP-43 and SCG-10, are syne

134 Examples include the neural-specific TRK receptors, the VEGF and angiopoietin